Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change CESC 10 104182625 104182625 + Missense_Mutation SNP G G A TCGA-LP-A7HU-01A-11D-A33O-09 TCGA-LP-A7HU-10A-01D-A33O-09 g.chr10:104182625G>A c.778G>A c.(778-780)Gag>Aag p.E260K COAD 10 104181620 104181620 + Missense_Mutation SNP C C T TCGA-G4-6586-01A-11D-1771-10 TCGA-G4-6586-10A-01D-1771-10 g.chr10:104181620C>T c.284C>T c.(283-285)gCg>gTg p.A95V COAD 10 104182667 104182667 + Missense_Mutation SNP G G A TCGA-D5-6540-01A-11D-1719-10 TCGA-D5-6540-10A-01D-1719-10 g.chr10:104182667G>A c.820G>A c.(820-822)Gac>Aac p.D274N COAD 10 104182675 104182675 + Silent SNP G G A TCGA-CM-6674-01A-11D-1835-10 TCGA-CM-6674-10A-01D-1835-10 g.chr10:104182675G>A c.828G>A c.(826-828)gaG>gaA p.E276E COADREAD 10 104181620 104181620 + Missense_Mutation SNP C C T TCGA-G4-6586-01A-11D-1771-10 TCGA-G4-6586-10A-01D-1771-10 g.chr10:104181620C>T c.284C>T c.(283-285)gCg>gTg p.A95V COADREAD 10 104182667 104182667 + Missense_Mutation SNP G G A TCGA-D5-6540-01A-11D-1719-10 TCGA-D5-6540-10A-01D-1719-10 g.chr10:104182667G>A c.820G>A c.(820-822)Gac>Aac p.D274N COADREAD 10 104182675 104182675 + Silent SNP G G A TCGA-CM-6674-01A-11D-1835-10 TCGA-CM-6674-10A-01D-1835-10 g.chr10:104182675G>A c.828G>A c.(826-828)gaG>gaA p.E276E LUAD 10 104182723 104182723 + Silent SNP C C T TCGA-97-7547-01A-11D-2036-08 TCGA-97-7547-10A-01D-2036-08 g.chr10:104182723C>T c.876C>T c.(874-876)ttC>ttT p.F292F SKCM 10 104181773 104181773 + Missense_Mutation SNP C C T TCGA-EE-A2MS-06A-11D-A197-08 TCGA-EE-A2MS-10A-01D-A199-08 g.chr10:104181773C>T c.437C>T c.(436-438)tCg>tTg p.S146L SKCM 10 104182012 104182012 + Missense_Mutation SNP C C T TCGA-FW-A3R5-06A-11D-A23B-08 TCGA-FW-A3R5-10A-01D-A23B-08 g.chr10:104182012C>T c.676C>T c.(676-678)Ctc>Ttc p.L226F

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 10 104174852 104174852 single base substitution C T upstream_gene_variant BLCA-CN 10 104184872 104184872 single base substitution C T downstream_gene_variant BLCA-US 10 104174879 104174879 single base substitution C T upstream_gene_variant BRCA-EU 10 104174185 104174185 single base substitution C G upstream_gene_variant BRCA-EU 10 104175113 104175113 single base substitution C T upstream_gene_variant BRCA-EU 10 104175156 104175156 single base substitution C G upstream_gene_variant BRCA-EU 10 104175287 104175287 single base substitution T C upstream_gene_variant BRCA-EU 10 104175841 104175841 single base substitution A G upstream_gene_variant BRCA-EU 10 104176197 104176197 deletion of <=200bp G - upstream_gene_variant BRCA-EU 10 104176843 104176843 single base substitution C T upstream_gene_variant BRCA-EU 10 104177470 104177470 single base substitution T C upstream_gene_variant BRCA-EU 10 104179676 104179676 single base substitution T A 5_prime_UTR_variant BRCA-EU 10 104179676 104179676 single base substitution T A exon_variant BRCA-EU 10 104179676 104179676 single base substitution T A intron_variant BRCA-EU 10 104179676 104179676 single base substitution T A upstream_gene_variant BRCA-EU 10 104180133 104180133 single base substitution C T 5_prime_UTR_variant BRCA-EU 10 104180133 104180133 single base substitution C T exon_variant BRCA-EU 10 104180133 104180133 single base substitution C T intron_variant BRCA-EU 10 104180133 104180133 single base substitution C T upstream_gene_variant BRCA-EU 10 104182875 104182875 single base substitution T G 3_prime_UTR_variant BRCA-EU 10 104182875 104182875 single base substitution T G downstream_gene_variant BRCA-EU 10 104183351 104183351 single base substitution G A downstream_gene_variant BRCA-EU 10 104183411 104183411 single base substitution C T downstream_gene_variant BRCA-EU 10 104184020 104184020 single base substitution C T downstream_gene_variant BRCA-EU 10 104185515 104185515 single base substitution C T downstream_gene_variant BRCA-EU 10 104186821 104186821 deletion of <=200bp A - downstream_gene_variant BRCA-EU 10 104186830 104186830 insertion of <=200bp - G downstream_gene_variant BRCA-EU 10 104187202 104187202 single base substitution G A downstream_gene_variant BRCA-FR 10 104182669 104182669 single base substitution C T downstream_gene_variant BRCA-FR 10 104182669 104182669 single base substitution C T synonymous_variant D270D 810C>T BRCA-FR 10 104182669 104182669 single base substitution C T synonymous_variant D274D 822C>T BRCA-FR 10 104183351 104183351 single base substitution G A downstream_gene_variant BRCA-FR 10 104183411 104183411 single base substitution C T downstream_gene_variant BRCA-UK 10 104181253 104181253 single base substitution G A downstream_gene_variant BRCA-UK 10 104181253 104181253 single base substitution G A missense_variant D153N 457G>A BRCA-UK 10 104181253 104181253 single base substitution G A missense_variant D62N 184G>A BRCA-UK 10 104181253 104181253 single base substitution G A missense_variant D66N 196G>A BRCA-US 10 104174725 104174725 single base substitution C A upstream_gene_variant BRCA-US 10 104175780 104175780 insertion of <=200bp - G upstream_gene_variant BRCA-US 10 104184498 104184498 single base substitution C A downstream_gene_variant BTCA-JP 10 104175026 104175026 single base substitution C T upstream_gene_variant BTCA-JP 10 104175781 104175781 deletion of <=200bp G - upstream_gene_variant BTCA-JP 10 104176584 104176584 single base substitution C T upstream_gene_variant BTCA-JP 10 104179375 104179375 single base substitution G C intron_variant BTCA-JP 10 104179375 104179375 single base substitution G C upstream_gene_variant BTCA-JP 10 104180855 104180855 single base substitution A C 5_prime_UTR_variant BTCA-JP 10 104180855 104180855 single base substitution A C downstream_gene_variant BTCA-JP 10 104180855 104180855 single base substitution A C missense_variant K77T 230A>C BTCA-JP 10 104184953 104184953 single base substitution C G downstream_gene_variant CESC-US 10 104174660 104174660 single base substitution C T upstream_gene_variant CESC-US 10 104176175 104176175 single base substitution G T upstream_gene_variant CESC-US 10 104176302 104176302 single base substitution G A upstream_gene_variant CESC-US 10 104176405 104176405 single base substitution C T upstream_gene_variant CESC-US 10 104176486 104176486 single base substitution G A upstream_gene_variant CESC-US 10 104180693 104180693 single base substitution G A 5_prime_UTR_variant CESC-US 10 104180693 104180693 single base substitution G A downstream_gene_variant CESC-US 10 104180693 104180693 single base substitution G A intron_variant CESC-US 10 104182625 104182625 single base substitution G A downstream_gene_variant CESC-US 10 104182625 104182625 single base substitution G A missense_variant E256K 766G>A CESC-US 10 104182625 104182625 single base substitution G A missense_variant E260K 778G>A CESC-US 10 104183034 104183034 single base substitution G A downstream_gene_variant CESC-US 10 104184033 104184033 single base substitution G T downstream_gene_variant CESC-US 10 104184490 104184490 single base substitution G A downstream_gene_variant CLLE-ES 10 104175768 104175768 single base substitution C G upstream_gene_variant COAD-US 10 104174744 104174744 single base substitution G A upstream_gene_variant COAD-US 10 104175781 104175781 deletion of <=200bp G - upstream_gene_variant COAD-US 10 104176197 104176197 deletion of <=200bp G - upstream_gene_variant COAD-US 10 104176203 104176203 deletion of <=200bp C - upstream_gene_variant COAD-US 10 104176782 104176782 single base substitution G A upstream_gene_variant COAD-US 10 104179968 104179968 deletion of <=200bp C - 5_prime_UTR_variant COAD-US 10 104179968 104179968 deletion of <=200bp C - exon_variant COAD-US 10 104179968 104179968 deletion of <=200bp C - frameshift_variant S32 COAD-US 10 104179968 104179968 deletion of <=200bp C - intron_variant COAD-US 10 104179968 104179968 deletion of <=200bp C - upstream_gene_variant COAD-US 10 104181620 104181620 single base substitution C T downstream_gene_variant COAD-US 10 104181620 104181620 single base substitution C T missense_variant A91V 272C>T COAD-US 10 104181620 104181620 single base substitution C T missense_variant A95V 284C>T COAD-US 10 104182667 104182667 single base substitution G A downstream_gene_variant COAD-US 10 104182667 104182667 single base substitution G A missense_variant D270N 808G>A COAD-US 10 104182667 104182667 single base substitution G A missense_variant D274N 820G>A COAD-US 10 104183229 104183229 single base substitution G A downstream_gene_variant COAD-US 10 104184052 104184052 single base substitution G A downstream_gene_variant COAD-US 10 104184081 104184081 single base substitution G A downstream_gene_variant COAD-US 10 104184086 104184086 single base substitution G A downstream_gene_variant COAD-US 10 104184467 104184467 single base substitution C T downstream_gene_variant COCA-CN 10 104176160 104176160 single base substitution G A upstream_gene_variant COCA-CN 10 104180031 104180031 single base substitution T C 5_prime_UTR_variant COCA-CN 10 104180031 104180031 single base substitution T C exon_variant COCA-CN 10 104180031 104180031 single base substitution T C intron_variant COCA-CN 10 104180031 104180031 single base substitution T C missense_variant I53T 158T>C COCA-CN 10 104180031 104180031 single base substitution T C upstream_gene_variant COCA-CN 10 104183385 104183385 single base substitution G A downstream_gene_variant COCA-CN 10 104184080 104184080 single base substitution C T downstream_gene_variant COCA-CN 10 104185186 104185186 single base substitution A C downstream_gene_variant ESAD-UK 10 104174170 104174170 deletion of <=200bp T - upstream_gene_variant ESAD-UK 10 104175496 104175496 single base substitution G A upstream_gene_variant ESAD-UK 10 104176747 104176747 single base substitution A C upstream_gene_variant ESAD-UK 10 104177154 104177154 single base substitution G C upstream_gene_variant ESAD-UK 10 104178071 104178071 single base substitution T C upstream_gene_variant ESAD-UK 10 104178092 104178092 single base substitution G C upstream_gene_variant ESAD-UK 10 104178909 104178909 single base substitution G A upstream_gene_variant ESAD-UK 10 104179471 104179471 single base substitution C A intron_variant ESAD-UK 10 104179471 104179471 single base substitution C A upstream_gene_variant ESAD-UK 10 104180785 104180785 single base substitution G A 5_prime_UTR_variant ESAD-UK 10 104180785 104180785 single base substitution G A downstream_gene_variant ESAD-UK 10 104180785 104180785 single base substitution G A intron_variant ESAD-UK 10 104182613 104182613 single base substitution C T downstream_gene_variant ESAD-UK 10 104182613 104182613 single base substitution C T missense_variant H252Y 754C>T ESAD-UK 10 104182613 104182613 single base substitution C T missense_variant H256Y 766C>T ESAD-UK 10 104187351 104187351 single base substitution G A downstream_gene_variant KIRC-US 10 104184284 104184284 single base substitution T A downstream_gene_variant KIRP-US 10 104176443 104176443 single base substitution G C upstream_gene_variant KIRP-US 10 104182716 104182716 insertion of <=200bp - G downstream_gene_variant KIRP-US 10 104182716 104182716 insertion of <=200bp - G frameshift_variant A286G? KIRP-US 10 104182716 104182716 insertion of <=200bp - G frameshift_variant A290G? KIRP-US 10 104184514 104184514 single base substitution C T downstream_gene_variant LAML-KR 10 104184953 104184953 single base substitution C G downstream_gene_variant LGG-US 10 104184887 104184887 single base substitution G A downstream_gene_variant LICA-FR 10 104174840 104174840 single base substitution C A upstream_gene_variant LICA-FR 10 104176197 104176197 deletion of <=200bp G - upstream_gene_variant LICA-FR 10 104181185 104181185 single base substitution G A downstream_gene_variant LICA-FR 10 104181185 104181185 single base substitution G A missense_variant R130Q 389G>A LICA-FR 10 104181185 104181185 single base substitution G A missense_variant R39Q 116G>A LICA-FR 10 104181185 104181185 single base substitution G A missense_variant R43Q 128G>A LINC-JP 10 104174817 104174817 single base substitution C T upstream_gene_variant LINC-JP 10 104181128 104181128 single base substitution G A downstream_gene_variant LINC-JP 10 104181128 104181128 single base substitution G A stop_gained W111* 332G>A LINC-JP 10 104181128 104181128 single base substitution G A stop_gained W20* 59G>A LINC-JP 10 104181128 104181128 single base substitution G A stop_gained W24* 71G>A LINC-JP 10 104183025 104183025 single base substitution T C downstream_gene_variant LINC-JP 10 104185491 104185491 single base substitution G A downstream_gene_variant LIRI-JP 10 104174959 104174959 insertion of <=200bp - G upstream_gene_variant LIRI-JP 10 104175944 104175944 single base substitution G T upstream_gene_variant LIRI-JP 10 104179106 104179106 single base substitution G A 5_prime_UTR_variant LIRI-JP 10 104179106 104179106 single base substitution G A exon_variant LIRI-JP 10 104179106 104179106 single base substitution G A upstream_gene_variant LIRI-JP 10 104183827 104183827 insertion of <=200bp - C downstream_gene_variant LIRI-JP 10 104186885 104186885 single base substitution T C downstream_gene_variant LIRI-JP 10 104186908 104186908 single base substitution C T downstream_gene_variant LUSC-KR 10 104178050 104178050 single base substitution A T upstream_gene_variant LUSC-KR 10 104178153 104178153 single base substitution C A upstream_gene_variant LUSC-KR 10 104181308 104181308 single base substitution C T downstream_gene_variant LUSC-KR 10 104181308 104181308 single base substitution C T intron_variant LUSC-US 10 104174911 104174911 single base substitution C A upstream_gene_variant LUSC-US 10 104176612 104176612 single base substitution G A upstream_gene_variant LUSC-US 10 104176760 104176760 single base substitution G A upstream_gene_variant MALY-DE 10 104174310 104174310 single base substitution C A upstream_gene_variant MALY-DE 10 104176263 104176263 deletion of <=200bp G - upstream_gene_variant MALY-DE 10 104178067 104178067 single base substitution T A upstream_gene_variant MALY-DE 10 104181018 104181018 single base substitution C T downstream_gene_variant MALY-DE 10 104181018 104181018 single base substitution C T intron_variant MALY-DE 10 104187154 104187154 single base substitution C T downstream_gene_variant MELA-AU 10 104174168 104174168 single base substitution C T upstream_gene_variant MELA-AU 10 104174339 104174339 single base substitution G A upstream_gene_variant MELA-AU 10 104174591 104174591 single base substitution C T upstream_gene_variant MELA-AU 10 104174684 104174684 single base substitution C T upstream_gene_variant MELA-AU 10 104174790 104174790 single base substitution C T upstream_gene_variant MELA-AU 10 104174820 104174820 single base substitution C T upstream_gene_variant MELA-AU 10 104175142 104175142 single base substitution G C upstream_gene_variant MELA-AU 10 104175196 104175196 single base substitution G A upstream_gene_variant MELA-AU 10 104175300 104175300 single base substitution A G upstream_gene_variant MELA-AU 10 104175352 104175352 single base substitution C T upstream_gene_variant MELA-AU 10 104175560 104175560 single base substitution C T upstream_gene_variant MELA-AU 10 104175561 104175561 single base substitution C T upstream_gene_variant MELA-AU 10 104175675 104175675 single base substitution C T upstream_gene_variant MELA-AU 10 104175751 104175751 single base substitution C T upstream_gene_variant MELA-AU 10 104175845 104175845 single base substitution G A upstream_gene_variant MELA-AU 10 104175863 104175863 single base substitution G A upstream_gene_variant MELA-AU 10 104175891 104175891 single base substitution G A upstream_gene_variant MELA-AU 10 104175928 104175928 single base substitution G A upstream_gene_variant MELA-AU 10 104175948 104175948 single base substitution G A upstream_gene_variant MELA-AU 10 104176046 104176046 single base substitution G A upstream_gene_variant MELA-AU 10 104176151 104176151 single base substitution G A upstream_gene_variant MELA-AU 10 104176252 104176253 multiple base substitution (>=2bp and <=200bp) GG AA upstream_gene_variant MELA-AU 10 104176285 104176285 single base substitution G A upstream_gene_variant MELA-AU 10 104176327 104176327 single base substitution C T upstream_gene_variant MELA-AU 10 104176395 104176395 single base substitution G A upstream_gene_variant MELA-AU 10 104176661 104176661 single base substitution G A upstream_gene_variant MELA-AU 10 104176717 104176717 single base substitution G A upstream_gene_variant MELA-AU 10 104176743 104176743 single base substitution G A upstream_gene_variant MELA-AU 10 104176746 104176746 single base substitution G A upstream_gene_variant MELA-AU 10 104176867 104176867 single base substitution C T upstream_gene_variant MELA-AU 10 104176890 104176890 single base substitution G A upstream_gene_variant MELA-AU 10 104177224 104177224 single base substitution G A upstream_gene_variant MELA-AU 10 104177230 104177230 single base substitution G A upstream_gene_variant MELA-AU 10 104177840 104177840 single base substitution A G upstream_gene_variant MELA-AU 10 104177848 104177848 single base substitution G A upstream_gene_variant MELA-AU 10 104178226 104178226 single base substitution G A upstream_gene_variant MELA-AU 10 104178259 104178259 single base substitution C T upstream_gene_variant MELA-AU 10 104178810 104178810 single base substitution C T upstream_gene_variant MELA-AU 10 104179099 104179099 single base substitution G A 5_prime_UTR_variant MELA-AU 10 104179099 104179099 single base substitution G A exon_variant MELA-AU 10 104179099 104179099 single base substitution G A upstream_gene_variant MELA-AU 10 104179345 104179345 single base substitution G A intron_variant MELA-AU 10 104179345 104179345 single base substitution G A upstream_gene_variant MELA-AU 10 104179348 104179348 single base substitution G A intron_variant MELA-AU 10 104179348 104179348 single base substitution G A upstream_gene_variant MELA-AU 10 104179431 104179432 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 10 104179431 104179432 multiple base substitution (>=2bp and <=200bp) GG AA upstream_gene_variant MELA-AU 10 104179452 104179452 single base substitution G A intron_variant MELA-AU 10 104179452 104179452 single base substitution G A upstream_gene_variant MELA-AU 10 104179853 104179853 single base substitution G A 5_prime_UTR_variant MELA-AU 10 104179853 104179853 single base substitution G A exon_variant MELA-AU 10 104179853 104179853 single base substitution G A intron_variant MELA-AU 10 104179853 104179853 single base substitution G A upstream_gene_variant MELA-AU 10 104180735 104180735 single base substitution G A 5_prime_UTR_variant MELA-AU 10 104180735 104180735 single base substitution G A downstream_gene_variant MELA-AU 10 104180735 104180735 single base substitution G A intron_variant MELA-AU 10 104180769 104180769 single base substitution C T 5_prime_UTR_premature_start_codon_gain_variant MELA-AU 10 104180769 104180769 single base substitution C T downstream_gene_variant MELA-AU 10 104180769 104180769 single base substitution C T intron_variant MELA-AU 10 104180912 104180912 single base substitution G A downstream_gene_variant MELA-AU 10 104180912 104180912 single base substitution G A missense_variant G5E 14G>A MELA-AU 10 104180912 104180912 single base substitution G A missense_variant G96E 287G>A MELA-AU 10 104180912 104180912 single base substitution G A missense_variant G9E 26G>A MELA-AU 10 104180956 104180956 single base substitution G A downstream_gene_variant MELA-AU 10 104180956 104180956 single base substitution G A intron_variant MELA-AU 10 104181463 104181463 single base substitution G A downstream_gene_variant MELA-AU 10 104181463 104181463 single base substitution G A intron_variant MELA-AU 10 104182344 104182344 single base substitution C T downstream_gene_variant MELA-AU 10 104182344 104182344 single base substitution C T intron_variant MELA-AU 10 104182469 104182469 single base substitution C T downstream_gene_variant MELA-AU 10 104182469 104182469 single base substitution C T intron_variant MELA-AU 10 104182931 104182931 single base substitution G A downstream_gene_variant MELA-AU 10 104183444 104183444 single base substitution C T downstream_gene_variant MELA-AU 10 104183644 104183644 single base substitution C T downstream_gene_variant MELA-AU 10 104184969 104184969 single base substitution G A downstream_gene_variant MELA-AU 10 104185958 104185958 single base substitution C G downstream_gene_variant MELA-AU 10 104186639 104186639 single base substitution G A downstream_gene_variant MELA-AU 10 104186829 104186829 single base substitution A G downstream_gene_variant MELA-AU 10 104187084 104187084 single base substitution C G downstream_gene_variant MELA-AU 10 104187350 104187350 single base substitution C T downstream_gene_variant ORCA-IN 10 104177840 104177840 single base substitution A G upstream_gene_variant ORCA-IN 10 104181853 104181853 single base substitution C A downstream_gene_variant ORCA-IN 10 104181853 104181853 single base substitution C A missense_variant L169I 505C>A ORCA-IN 10 104181853 104181853 single base substitution C A missense_variant L173I 517C>A ORCA-IN 10 104183570 104183570 single base substitution G A downstream_gene_variant ORCA-IN 10 104184147 104184147 single base substitution G T downstream_gene_variant OV-AU 10 104176273 104176273 single base substitution G A upstream_gene_variant OV-AU 10 104182086 104182086 single base substitution C T downstream_gene_variant OV-AU 10 104182086 104182086 single base substitution C T intron_variant OV-US 10 104176573 104176573 insertion of <=200bp - G upstream_gene_variant PACA-AU 10 104175923 104175923 single base substitution T A upstream_gene_variant PACA-AU 10 104177838 104177838 single base substitution A G upstream_gene_variant PACA-AU 10 104178660 104178660 single base substitution C T upstream_gene_variant PACA-AU 10 104183173 104183173 single base substitution G A downstream_gene_variant PACA-AU 10 104183213 104183213 single base substitution G A downstream_gene_variant PACA-AU 10 104183553 104183553 insertion of <=200bp - A downstream_gene_variant PACA-CA 10 104174455 104174455 single base substitution G A upstream_gene_variant PACA-CA 10 104175854 104175854 single base substitution C T upstream_gene_variant PACA-CA 10 104180169 104180169 single base substitution T C 5_prime_UTR_variant PACA-CA 10 104180169 104180169 single base substitution T C exon_variant PACA-CA 10 104180169 104180169 single base substitution T C intron_variant PACA-CA 10 104180169 104180169 single base substitution T C upstream_gene_variant PACA-CA 10 104181279 104181279 single base substitution G A downstream_gene_variant PACA-CA 10 104181279 104181279 single base substitution G A intron_variant PACA-CA 10 104186829 104186829 single base substitution A G downstream_gene_variant PBCA-DE 10 104176203 104176203 insertion of <=200bp - C upstream_gene_variant PBCA-DE 10 104176509 104176509 single base substitution G A upstream_gene_variant PBCA-DE 10 104177927 104177928 deletion of <=200bp AC - upstream_gene_variant PRAD-UK 10 104174107 104174107 single base substitution C T upstream_gene_variant PRAD-UK 10 104176038 104176038 single base substitution A T upstream_gene_variant PRAD-US 10 104176689 104176689 deletion of <=200bp G - upstream_gene_variant READ-US 10 104176584 104176584 single base substitution C T upstream_gene_variant READ-US 10 104180897 104180897 single base substitution C T 5_prime_UTR_premature_start_codon_gain_variant READ-US 10 104180897 104180897 single base substitution C T downstream_gene_variant READ-US 10 104180897 104180897 single base substitution C T missense_variant P4L 11C>T READ-US 10 104180897 104180897 single base substitution C T missense_variant P91L 272C>T READ-US 10 104183302 104183302 single base substitution C T downstream_gene_variant RECA-EU 10 104180322 104180322 single base substitution C T 5_prime_UTR_premature_start_codon_gain_variant RECA-EU 10 104180322 104180322 single base substitution C T downstream_gene_variant RECA-EU 10 104180322 104180322 single base substitution C T intron_variant RECA-EU 10 104180322 104180322 single base substitution C T upstream_gene_variant RECA-EU 10 104183288 104183288 single base substitution C T downstream_gene_variant SKCA-BR 10 104176320 104176320 single base substitution A G upstream_gene_variant SKCA-BR 10 104177396 104177396 single base substitution G A upstream_gene_variant SKCA-BR 10 104184213 104184213 single base substitution G A downstream_gene_variant SKCM-US 10 104174648 104174648 single base substitution C T upstream_gene_variant SKCM-US 10 104174684 104174684 single base substitution C T upstream_gene_variant SKCM-US 10 104174701 104174701 single base substitution C T upstream_gene_variant SKCM-US 10 104174841 104174841 single base substitution G A upstream_gene_variant SKCM-US 10 104174892 104174892 single base substitution G A upstream_gene_variant SKCM-US 10 104175780 104175780 insertion of <=200bp - G upstream_gene_variant SKCM-US 10 104175790 104175790 single base substitution C T upstream_gene_variant SKCM-US 10 104175794 104175794 single base substitution G A upstream_gene_variant SKCM-US 10 104175826 104175826 single base substitution G A upstream_gene_variant SKCM-US 10 104175860 104175860 single base substitution G A upstream_gene_variant SKCM-US 10 104175863 104175863 single base substitution G A upstream_gene_variant SKCM-US 10 104175873 104175873 single base substitution C T upstream_gene_variant SKCM-US 10 104176151 104176151 single base substitution G A upstream_gene_variant SKCM-US 10 104176224 104176224 single base substitution G A upstream_gene_variant SKCM-US 10 104176318 104176318 single base substitution G A upstream_gene_variant SKCM-US 10 104176327 104176327 single base substitution C T upstream_gene_variant SKCM-US 10 104176434 104176434 single base substitution C T upstream_gene_variant SKCM-US 10 104176438 104176438 single base substitution G A upstream_gene_variant SKCM-US 10 104176550 104176550 single base substitution G T upstream_gene_variant SKCM-US 10 104176661 104176661 single base substitution G A upstream_gene_variant SKCM-US 10 104176737 104176737 single base substitution C T upstream_gene_variant SKCM-US 10 104176757 104176757 single base substitution G A upstream_gene_variant SKCM-US 10 104181773 104181773 single base substitution C T downstream_gene_variant SKCM-US 10 104181773 104181773 single base substitution C T missense_variant S142L 425C>T SKCM-US 10 104181773 104181773 single base substitution C T missense_variant S146L 437C>T SKCM-US 10 104182012 104182012 single base substitution C T downstream_gene_variant SKCM-US 10 104182012 104182012 single base substitution C T missense_variant L222F 664C>T SKCM-US 10 104182012 104182012 single base substitution C T missense_variant L226F 676C>T SKCM-US 10 104183554 104183554 single base substitution C T downstream_gene_variant SKCM-US 10 104184490 104184490 single base substitution G A downstream_gene_variant STAD-US 10 104173948 104173948 single base substitution C A upstream_gene_variant STAD-US 10 104174761 104174761 single base substitution G A upstream_gene_variant STAD-US 10 104174786 104174786 single base substitution T C upstream_gene_variant STAD-US 10 104174959 104174959 deletion of <=200bp G - upstream_gene_variant STAD-US 10 104174959 104174959 insertion of <=200bp - G upstream_gene_variant STAD-US 10 104175781 104175781 deletion of <=200bp G - upstream_gene_variant STAD-US 10 104176197 104176197 deletion of <=200bp G - upstream_gene_variant STAD-US 10 104176654 104176654 single base substitution G A upstream_gene_variant STAD-US 10 104176728 104176728 single base substitution C T upstream_gene_variant STAD-US 10 104176760 104176760 single base substitution G A upstream_gene_variant STAD-US 10 104181683 104181683 single base substitution T C downstream_gene_variant STAD-US 10 104181683 104181683 single base substitution T C missense_variant L112P 335T>C STAD-US 10 104181683 104181683 single base substitution T C missense_variant L116P 347T>C STAD-US 10 104182697 104182697 single base substitution G T downstream_gene_variant STAD-US 10 104182697 104182697 single base substitution G T missense_variant V280L 838G>T STAD-US 10 104182697 104182697 single base substitution G T missense_variant V284L 850G>T STAD-US 10 104183602 104183602 single base substitution G A downstream_gene_variant STAD-US 10 104184490 104184490 single base substitution G A downstream_gene_variant STAD-US 10 104184490 104184490 single base substitution G T downstream_gene_variant UCEC-US 10 104174837 104174837 single base substitution C A upstream_gene_variant UCEC-US 10 104176356 104176356 single base substitution C T upstream_gene_variant UCEC-US 10 104176398 104176398 single base substitution G C upstream_gene_variant UCEC-US 10 104176485 104176485 single base substitution C T upstream_gene_variant UCEC-US 10 104183215 104183215 single base substitution G T downstream_gene_variant UCEC-US 10 104183256 104183256 single base substitution C A downstream_gene_variant UCEC-US 10 104183283 104183283 single base substitution G A downstream_gene_variant UCEC-US 10 104183288 104183288 single base substitution C G downstream_gene_variant UCEC-US 10 104183303 104183303 single base substitution G T downstream_gene_variant UCEC-US 10 104183425 104183425 single base substitution C T downstream_gene_variant UCEC-US 10 104183456 104183456 single base substitution G A downstream_gene_variant UCEC-US 10 104184080 104184080 single base substitution C T downstream_gene_variant UCEC-US 10 104184459 104184459 single base substitution C A downstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand TCGA-G4-6586-01 COSM1345480 c.545C>T p.A182V Substitution - Missense 10:102421863-102421863 + SCC-25 COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + UM-SCC-11B COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + TCGA-A6-5661-01 COSM3685969 c.95delC p.H34fs*87 Deletion - Frameshift 10:102420211-102420211 + SCC-9 COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + WSU-HN13 COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + T2389 COSM4683865 c.1019G>A p.R340Q Substitution - Missense 10:102422848-102422848 + OSCC-GB_00610111 COSM4886788 c.778C>A p.L260I Substitution - Missense 10:102422096-102422096 + TCGA-LP-A7HU-01 COSM4825725 c.1039G>A p.E347K Substitution - Missense 10:102422868-102422868 + PD1768a COSM30513 c.304G>A p.G102R Substitution - Missense 10:102421172-102421172 + 93VU147T COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + BD173T COSM5500486 c.230A>C p.K77T Substitution - Missense 10:102421098-102421098 + TCGA-EE-A2MS-06 COSM3433774 c.698C>T p.S233L Substitution - Missense 10:102422016-102422016 + UM-SCC-4 COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + WSU-HN8 COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + CAL33 COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + TCGA-FW-A3R5-06 COSM3866401 c.937C>T p.L313F Substitution - Missense 10:102422255-102422255 + UM-SCC-2 COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + T1772 COSM4683864 c.970G>A p.V324I Substitution - Missense 10:102422288-102422288 + HCC171T COSM3665456 c.332G>A p.W111* Substitution - Nonsense 10:102421371-102421371 + MO_1176 COSM5564593 c.737G>T p.R246L Substitution - Missense 10:102422055-102422055 + CHC793T COSM4801343 c.389G>A p.R130Q Substitution - Missense 10:102421428-102421428 + UD-SCC-2 COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + CSCC-20-T COSM4445968 c.16C>T p.R6C Substitution - Missense 10:102420132-102420132 + NOKSI COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + WSU-HN12 COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + UM-SCC-47 COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + TCGA-D5-6540-01 COSM1345481 c.1081G>A p.D361N Substitution - Missense 10:102422910-102422910 + RH30SJ_ COSM2059303 c.593C>T p.A198V Substitution - Missense 10:102421911-102421911 + BHY COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + TCGA-G5-6233-01 COSM3414639 c.272C>T p.P91L Substitution - Missense 10:102421140-102421140 + BICR_22 COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + CHC793T COSM4801343 c.389G>A p.R130Q Substitution - Missense 10:102421428-102421428 + TCGA-HU-A4H3-01 COSM4011265 c.608T>C p.L203P Substitution - Missense 10:102421926-102421926 + WSU-HN6 COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + CSCC-31-T COSM4511774 c.348C>T p.L116L Substitution - coding silent 10:102421387-102421387 + Pat_44_B COSM5836154 c.394delC p.Q132fs*83 Deletion - Frameshift 10:102421433-102421433 + SC_9032 COSM5551640 c.714C>G p.D238E Substitution - Missense 10:102422032-102422032 + ESO-0019 COSM1252231 c.1105G>A p.A369T Substitution - Missense 10:102422934-102422934 + sysucc-311T COSM5477072 c.158T>C p.I53T Substitution - Missense 10:102420274-102420274 + TCGA-D7-A4YY-01 COSM4011266 c.1111G>T p.V371L Substitution - Missense 10:102422940-102422940 + HCC171 COSM3665456 c.332G>A p.W111* Substitution - Nonsense 10:102421371-102421371 + UM-SCC-17B COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 + CAL27 COSM4591596 c.1147G>T p.V383F Substitution - Missense 10:102422976-102422976 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.380081 10q24.32 610287

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer C T IntronicSNV . c.53+79C>T 10 104181018 DLBCL C T Missense p.S146L c.437C>T 10 104181773 CM G A Missense p.A282T c.844G>A 10 104182691 ESCA