| Disease associated variation - GWASdb |
| Chr | Pos | SNP ID(dbSNP 142) | Ref | Alt | Ori SNP ID | P-value | Drug Name | Drug Anno | GWAS Trait | HPO ID | DO ID | AA | Type | Trait or Drug |
|---|
| 10 | 80923862 | rs1749824 | C | A | rs1749824 | 8.91E-05 | ALDOSTERONE | BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN | Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) | HPOID:0011025 | DOID:10763 | G | intron | GWASdb_drug |
| 10 | 80834685 | rs4980022 | C | T | rs4980022 | 4.95E-04 | | | Smoking initiation | HPOID:0000707 | DOID:0050742 | C | intron | GWASdb_trait |
| 10 | 80841148 | rs704010 | T | C | rs704010 | 4.00E-09 | | | Breast cancer | HPOID:0003002 | DOID:1612 | G | intron | GWASdb_trait |
| 10 | 80841148 | rs704010 | T | C | rs704010 | 7.00E-22 | | | Breast cancer | HPOID:0003002 | DOID:1612 | G | intron | GWASdb_trait |
| 10 | 80843548 | rs4980027 | C | A | rs4980027 | 7.51E-04 | | | Response to TNF antagonist treatment | HPOID:0001370 | DOID:7148 | C | intron | GWASdb_trait |
| 10 | 80845411 | rs1250009 | G | A | rs1250009 | 1.60E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | T | intron | GWASdb_trait |
| 10 | 80846608 | rs1250005 | T | C | rs1250005 | 1.60E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | G | intron | GWASdb_trait |
| 10 | 80846814 | rs1250003 | C | T | rs1250003 | 1.60E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | A | intron | GWASdb_trait |
| 10 | 80849336 | rs1250000 | A | G | rs1250000 | 1.80E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | C | intron | GWASdb_trait |
| 10 | 80851257 | rs719338 | G | T | rs719338 | 2.10E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | A | intron | GWASdb_trait |
| 10 | 80852602 | rs873823 | G | A | rs873823 | 4.40E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | T | intron | GWASdb_trait |
| 10 | 80853508 | rs1250013 | C | T | rs1250013 | 3.56E-04 | | | Amyotrophic lateral sclerosis (sporadic) | HPOID:0007354 | DOID:332 | G | intron | GWASdb_trait |
| 10 | 80855423 | rs10762844 | G | A | rs10762844 | 8.50E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | A | intron | GWASdb_trait |
| 10 | 80855650 | rs11002811 | G | A | rs11002811 | 2.60E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | G | intron | GWASdb_trait |
| 10 | 80857533 | rs11002813 | C | T | rs11002813 | 3.40E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | C | intron | GWASdb_trait |
| 10 | 80857533 | rs11002813 | C | T | rs11002813 | 6.76E-04 | | | Smoking cessation | HPOID:0000707 | DOID:0050742 | C | intron | GWASdb_trait |
| 10 | 80858473 | rs11002814 | G | A | rs11002814 | 3.30E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | G | intron | GWASdb_trait |
| 10 | 80858592 | rs11002816 | G | A | rs11002816 | 3.30E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | G | intron | GWASdb_trait |
| 10 | 80872483 | rs11002824 | C | G | rs11002824 | 4.00E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | C | intron | GWASdb_trait |
| 10 | 80873443 | rs16936863 | T | G | rs16936863 | 4.00E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | G | intron | GWASdb_trait |
| 10 | 80873608 | rs17557872 | A | G | rs17557872 | 3.90E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | G | intron | GWASdb_trait |
| 10 | 80873883 | rs11002825 | C | A | rs11002825 | 4.00E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | C | intron | GWASdb_trait |
| 10 | 80874092 | rs11002826 | G | A | rs11002826 | 3.90E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | G | intron | GWASdb_trait |
| 10 | 80878219 | rs4336976 | T | C | rs4336976 | 4.18E-04 | | | Type 2 diabetes | HPOID:0005978 | DOID:9352 | C | intron | GWASdb_trait |
| 10 | 80880435 | rs11002832 | C | G | rs11002832 | 5.10E-04 | | | Type 2 diabetes | HPOID:0005978 | DOID:9352 | C | intron | GWASdb_trait |
| 10 | 80880900 | rs11002835 | C | A | rs11002835 | 7.78E-04 | | | Type 2 diabetes | HPOID:0005978 | DOID:9352 | C | intron | GWASdb_trait |
| 10 | 80916381 | rs780153 | C | G | rs780153 | 7.60E-06 | | | Urinary metabolites | HPOID:0000079 | DOID:557 | C | intron | GWASdb_trait |
| 10 | 80918572 | rs779932 | G | A | rs779932 | 1.50E-06 | | | Urinary metabolites | HPOID:0000079 | DOID:557 | C | intron | GWASdb_trait |
| 10 | 80919442 | rs749821 | G | T | rs749821 | 1.43E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | C | intron | GWASdb_trait |
| 10 | 80919442 | rs749821 | G | T | rs749821 | 0.000436 | | | fMRI brain tests in schizophrenia | HPOID:0100753 | DOID:5419 | C | intron | GWASdb_trait |
| 10 | 80920370 | rs4980038 | A | G | rs4980038 | 0.000436 | | | fMRI brain tests in schizophrenia | HPOID:0100753 | DOID:5419 | A | intron | GWASdb_trait |
| 10 | 80921864 | rs697241 | A | G | rs697241 | 1.90E-05 | | | Urinary metabolites | HPOID:0000079 | DOID:557 | C | UTR-5 | GWASdb_trait |
| 10 | 80923862 | rs1749824 | C | A | rs1749824 | 8.10E-05 | | | End-stage renal disease | HPOID:0003774 | DOID:783 | G | intron | GWASdb_trait |
| 10 | 80923862 | rs1749824 | C | A | rs1749824 | 6.50E-13 | | | Meningococcal disease | HPOID:0001287 | DOID:9931 | G | intron | GWASdb_trait |
| 10 | 80923862 | rs1749824 | C | A | rs1749824 | 8.91E-05 | | | Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) | HPOID:0011025 | DOID:10763 | G | intron | GWASdb_trait |
| 10 | 80925577 | rs7916441 | G | C | rs7916441 | 6.00E-10 | | | Height | HPOID:0000002 | NA | G | intron | GWASdb_trait |
| 10 | 80927651 | rs703992 | C | G | rs703992 | 7.00E-07 | | | Urinary metabolites | HPOID:0000079 | DOID:557 | C | intron | GWASdb_trait |
| 10 | 80928793 | rs1815314 | G | A | rs1815314 | 2.20E-05 | | | Urinary metabolites | HPOID:0000079 | DOID:557 | G | intron | GWASdb_trait |
| 10 | 80929130 | rs703991 | G | A | rs703991 | 1.80E-05 | | | Urinary metabolites | HPOID:0000079 | DOID:557 | T | intron | GWASdb_trait |
| 10 | 80931240 | rs703989 | T | A | rs703989 | 8.74E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | T | intron | GWASdb_trait |
| 10 | 80931240 | rs703989 | T | A | rs703989 | 3.40E-06 | | | Urinary metabolites | HPOID:0000079 | DOID:557 | T | intron | GWASdb_trait |
| 10 | 80931481 | rs780151 | G | A | rs780151 | 2.00E-09 | | | Height | HPOID:0000002 | NA | C | intron | GWASdb_trait |
| 10 | 80931481 | rs780151 | G | A | rs780151 | 3.86E-05 | | | Weight | HPOID:0004323 | DOID:9970 | C | intron | GWASdb_trait |
| 10 | 80932607 | rs10824726 | T | G | rs10824726 | 8.16E-05 | | | Osteoarthritis (knee and hip) | HPOID:0002758 | DOID:8398 | G | intron | GWASdb_trait |
| 10 | 80932607 | rs10824726 | T | G | rs10824726 | 8.35E-06 | | | Osteoarthritis (knee and hip) | HPOID:0002758 | DOID:8398 | G | intron | GWASdb_trait |
| 10 | 80934948 | rs780149 | G | C | rs780149 | 9.00E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | G | intron | GWASdb_trait |
| 10 | 80935083 | rs780148 | G | C | rs780148 | 5.67E-05 | | | Multiple complex diseases | HPOID:0000118 | NA | G | intron | GWASdb_trait |
| 10 | 80935083 | rs780148 | G | C | rs780148 | 4.66E-05 | | | Bipolar disorder | HPOID:0007302 | DOID:3312 | G | intron | GWASdb_trait |
| 10 | 80942620 | rs810517 | C | T | rs810517 | 1.79E-05 | | | Multiple complex diseases | HPOID:0000118 | NA | A | intron | GWASdb_trait |
| 10 | 80942631 | rs12571751 | A | G | rs12571751 | 0.00000064 | | | Type 2 diabetes (males) | HPOID:0005978 | DOID:9352 | G | intron | GWASdb_trait |
| 10 | 80942631 | rs12571751 | A | G | rs12571751 | 0.0000012 | | | Type 2 diabetes (females) | HPOID:0005978 | DOID:9352 | G | intron | GWASdb_trait |
| 10 | 80942631 | rs12571751 | A | G | rs12571751 | 1.00E-10 | | | Type 2 diabetes | HPOID:0005978 | DOID:9352 | G | intron | GWASdb_trait |
| 10 | 80942631 | rs12571751 | A | G | rs12571751 | 2.00E-10 | | | Type 2 diabetes | HPOID:0005978 | DOID:9352 | G | intron | GWASdb_trait |
| 10 | 80942721 | rs703982 | A | G | rs703982 | 2.72E-05 | | | Multiple complex diseases | HPOID:0000118 | NA | T | intron | GWASdb_trait |
| 10 | 80944095 | rs703979 | T | C | rs703979 | 1.27E-04 | | | Osteoarthritis (knee and hip) | HPOID:0002758 | DOID:8398 | G | intron | GWASdb_trait |
| 10 | 80944095 | rs703979 | T | C | rs703979 | 1.68E-06 | | | Osteoarthritis (knee and hip) | HPOID:0002758 | DOID:8398 | G | intron | GWASdb_trait |
| 10 | 80944095 | rs703979 | T | C | rs703979 | 2.15E-04 | | | Osteoarthritis (knee and hip) | HPOID:0002758 | DOID:8398 | G | intron | GWASdb_trait |
| 10 | 80944095 | rs703979 | T | C | rs703979 | 3.92E-04 | | | Osteoarthritis (knee and hip) | HPOID:0002758 | DOID:8398 | G | intron | GWASdb_trait |
| 10 | 80952826 | rs703972 | G | C | rs703972 | 1.72E-04 | | | Attention deficit hyperactivity disorder | HPOID:0007018 | DOID:1094 | C | intron | GWASdb_trait |
| 10 | 80953136 | rs703970 | A | C | rs703970 | 5.00E-06 | | | Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) | HPOID:0000729|HPOID:0007018|HPOID:0007302|HPOID:0100753 | DOID:0060041|DOID:1094|DOID:3312|DOID:1470|DOID:5419 | C | intron | GWASdb_trait |
| 10 | 80953393 | rs703969 | G | C | rs703969 | 6.09E-05 | | | Serum metabolites | HPOID:0011111 | NA | G | intron | GWASdb_trait |
| 10 | 80955067 | rs703965 | C | T | rs703965 | 8.00E-06 | | | Bipolar disorder | HPOID:0007302 | DOID:3312 | G | intron | GWASdb_trait |
| 10 | 80959973 | rs10128264 | T | C | rs10128264 | 1.00E-06 | | | Response to methotrexate in juvenile idiopathic arthritis | HPOID:0005681 | DOID:676 | C | intron | GWASdb_trait |
| 10 | 80960828 | rs2802369 | C | A | rs2802369 | 7.00E-06 | | | Response to methotrexate in juvenile idiopathic arthritis | HPOID:0005681 | DOID:676 | G | intron | GWASdb_trait |
| 10 | 80962411 | rs2490275 | C | T | rs2490275 | 1.53E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | T | intron | GWASdb_trait |
| 10 | 80965109 | rs942794 | T | C | rs942794 | 1.06E-05 | | | Response to methotrexate in juvenile idiopathic arthritis | HPOID:0005681 | DOID:676 | C | intron | GWASdb_trait |
| 10 | 80966678 | rs745417 | C | T | rs745417 | 1.97E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | T | intron | GWASdb_trait |
| 10 | 80983786 | rs1250590 | C | A | rs1250590 | 0.000641686 | | | Hypertension (early onset hypertension) | HPOID:0000822 | DOID:10763 | G | intron | GWASdb_trait |
| 10 | 80986678 | rs1250592 | A | G | rs1250592 | 5.85E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | C | intron | GWASdb_trait |
| 10 | 81011589 | rs11002892 | C | T | rs11002892 | 3.50E-05 | | | Lipoprotein-associated phospholipase A2 activity and mass | HPOID:0010979 | DOID:3393 | A | intron | GWASdb_trait |
| 10 | 81015896 | rs11593576 | C | T | rs11593576 | 8.00E-07 | | | Vitiligo | HPOID:0001045 | DOID:12306 | C | intron | GWASdb_trait |
| 10 | 81032532 | rs1250546 | A | G | rs1250546 | 3.00E-18 | | | Inflammatory bowel disease | HPOID:0004386 | DOID:0050589 | C | intron | GWASdb_trait |
| 10 | 81032532 | rs1250546 | A | G | rs1250546 | 0.00000068 | | | Psoriasis | HPOID:0003765 | DOID:8893 | C | intron | GWASdb_trait |
| 10 | 81032885 | rs1250544 | G | A | rs1250544 | 7.00E-14 | | | Crohn's disease and psoriasis | HPOID:0100280 | DOID:8778|DOID:8893 | C | intron | GWASdb_trait |
| 10 | 81034670 | rs1250542 | G | A | rs1250542 | 4.00E-07 | | | Multiple sclerosis | HPOID:0000096|HPOID:0001967|HPOID:0009741|HPOID:0008664|HPOID:0001150|HPOID:0005450|HPOID:0005652|HPOID:0005686|HPOID:0005789|HPOID:0100923|HPOID:0100925|HPOID:0006623|HPOID:0100861|HPOID:0002694|HPOID:0004979|HPOID:0003881|HPOID:0003991|HPOID:0003854|HPOID:0003933|HPOID:0004030|HPOID:0100899|HPOID:0002634 | DOID:2377 | C | intron | GWASdb_trait |
| 10 | 81034913 | rs1250541 | G | C | rs1250541 | 1.07E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | G | intron | GWASdb_trait |
| 10 | 81036007 | rs1250540 | A | G | rs1250540 | 2.00E-06 | | | Multiple sclerosis | HPOID:0000096|HPOID:0001967|HPOID:0009741|HPOID:0008664|HPOID:0001150|HPOID:0005450|HPOID:0005652|HPOID:0005686|HPOID:0005789|HPOID:0100923|HPOID:0100925|HPOID:0006623|HPOID:0100861|HPOID:0002694|HPOID:0004979|HPOID:0003881|HPOID:0003991|HPOID:0003854|HPOID:0003933|HPOID:0004030|HPOID:0100899|HPOID:0002634 | DOID:2377 | T | intron | GWASdb_trait |
| 10 | 81036007 | rs1250540 | A | G | rs1250540 | 3.90E-04 | | | Multiple sclerosis | HPOID:0000096|HPOID:0001967|HPOID:0009741|HPOID:0008664|HPOID:0001150|HPOID:0005450|HPOID:0005652|HPOID:0005686|HPOID:0005789|HPOID:0100923|HPOID:0100925|HPOID:0006623|HPOID:0100861|HPOID:0002694|HPOID:0004979|HPOID:0003881|HPOID:0003991|HPOID:0003854|HPOID:0003933|HPOID:0004030|HPOID:0100899|HPOID:0002634 | DOID:2377 | T | intron | GWASdb_trait |
| 10 | 81037800 | rs1250538 | G | T | rs1250538 | 1.32E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | C | intron | GWASdb_trait |
| 10 | 81043707 | rs1892497 | C | T | rs1892497 | 5.42E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | C | intron | GWASdb_trait |
| 10 | 81047342 | rs1250564 | A | C | rs1250564 | 2.25E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | T | intron | GWASdb_trait |
| 10 | 81055626 | rs12355688 | C | T | rs12355688 | 6.00E-06 | | | Breast cancer | HPOID:0003002 | DOID:1612 | C | intron | GWASdb_trait |
| 10 | 81057833 | rs7905321 | G | A | rs7905321 | 5.73E-04 | | | Response to alcohol consumption (flushing response) | HPOID:0000707 | DOID:1574|DOID:0050741 | A,G | intron | GWASdb_trait |
| 10 | 81058027 | rs1250552 | A | G | rs1250552 | 7.34E-05 | | | Cognitive test performance | HPOID:0100543 | DOID:1561 | C | intron | GWASdb_trait |
| 10 | 81058027 | rs1250552 | A | G | rs1250552 | 9.00E-10 | | | Celiac disease | HPOID:0001438 | DOID:10608 | C | intron | GWASdb_trait |
| 10 | 81058027 | rs1250552 | A | G | rs1250552 | 9.00E-10 | | | Asthma | HPOID:0002099 | DOID:2841 | C | intron | GWASdb_trait |
| 10 | 81058027 | rs1250552 | A | G | rs1250552 | 9.09E-10 | | | Celiac disease and Rheumatoid arthritis | HPOID:0001438|HPOID:0001370 | DOID:10608|DOID:7148 | C | intron | GWASdb_trait |
| 10 | 81058027 | rs1250552 | A | G | rs1250552 | 8.00E-17 | | | Celiac disease | HPOID:0001438 | DOID:10608 | C | intron | GWASdb_trait |
| 10 | 81058027 | rs1250552 | A | G | rs1250552 | 9.09E-10 | | | Multiple sclerosis | HPOID:0000096|HPOID:0001967|HPOID:0009741|HPOID:0008664|HPOID:0001150|HPOID:0005450|HPOID:0005652|HPOID:0005686|HPOID:0005789|HPOID:0100923|HPOID:0100925|HPOID:0006623|HPOID:0100861|HPOID:0002694|HPOID:0004979|HPOID:0003881|HPOID:0003991|HPOID:0003854|HPOID:0003933|HPOID:0004030|HPOID:0100899|HPOID:0002634 | DOID:2377 | C | intron | GWASdb_trait |
| 10 | 81058027 | rs1250552 | A | G | rs1250552 | 3.13E-06 | | | Osteoarthritis | HPOID:0002758 | DOID:8398 | C | intron | GWASdb_trait |
| 10 | 81060005 | rs4246943 | G | A | rs4246943 | 3.21E-04 | | | Multiple complex diseases | HPOID:0000118 | NA | G | intron | GWASdb_trait |
| 10 | 81060317 | rs1250550 | C | A | rs1250550 | 6.00E-09 | | | Inflammatory bowel disease (early onset) | HPOID:0004386 | DOID:0050589 | G | intron | GWASdb_trait |
| 10 | 81060317 | rs1250550 | C | A | rs1250550 | 1.00E-30 | | | Crohn's disease | HPOID:0100280 | DOID:8778 | G | intron | GWASdb_trait |
| 10 | 81060317 | rs1250550 | C | A | rs1250550 | 6.00E-09 | | | Multiple sclerosis | HPOID:0000096|HPOID:0001967|HPOID:0009741|HPOID:0008664|HPOID:0001150|HPOID:0005450|HPOID:0005652|HPOID:0005686|HPOID:0005789|HPOID:0100923|HPOID:0100925|HPOID:0006623|HPOID:0100861|HPOID:0002694|HPOID:0004979|HPOID:0003881|HPOID:0003991|HPOID:0003854|HPOID:0003933|HPOID:0004030|HPOID:0100899|HPOID:0002634 | DOID:2377 | G | intron | GWASdb_trait |
| 10 | 81060317 | rs1250550 | C | A | rs1250550 | 6.00E-09 | | | Multiple sclerosis | HPOID:0000096|HPOID:0001967|HPOID:0009741|HPOID:0008664|HPOID:0001150|HPOID:0005450|HPOID:0005652|HPOID:0005686|HPOID:0005789|HPOID:0100923|HPOID:0100925|HPOID:0006623|HPOID:0100861|HPOID:0002694|HPOID:0004979|HPOID:0003881|HPOID:0003991|HPOID:0003854|HPOID:0003933|HPOID:0004030|HPOID:0100899|HPOID:0002634 | DOID:2377 | G | intron | GWASdb_trait |