PTM - CPLM Gene Name UniProt ID Type Position Code BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 36 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 40 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 126 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 226 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 233 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 416 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 425 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 537 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 340 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 305 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 610 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 490 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 94 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 410 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 516 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 102 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 19 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 38 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 441 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 497 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 546 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 446 K BIRC2; API1; MIHB; RNF48 Q13490 Ubiquitination 448 K

PTM - dbPAF Gene Name UniProt ID Position Type Species BIRC2; API1; MIHB; RNF48 Q13490 123 S Homo sapiens(Human) BIRC2; API1; MIHB; RNF48 Q13490 124 T Homo sapiens(Human) BIRC2; API1; MIHB; RNF48 Q13490 125 S Homo sapiens(Human) BIRC2; API1; MIHB; RNF48 Q13490 134 S Homo sapiens(Human) BIRC2; API1; MIHB; RNF48 Q13490 138 S Homo sapiens(Human) BIRC2; API1; MIHB; RNF48 Q13490 140 S Homo sapiens(Human) BIRC2; API1; MIHB; RNF48 Q13490 147 S Homo sapiens(Human) BIRC2; API1; MIHB; RNF48 Q13490 152 S Homo sapiens(Human) BIRC2; API1; MIHB; RNF48 Q13490 157 S Homo sapiens(Human) BIRC2; API1; MIHB; RNF48 Q13490 177 Y Homo sapiens(Human) BIRC2; API1; MIHB; RNF48 Q13490 98 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q13490 S98-p Phosphorylation DNWKLGDsPIQKHKQ Q13490 S140-p Phosphorylation NSFAHSLsPTLEHSs Q13490 S147-p Phosphorylation sPTLEHSsLFSGSYS Q13490 S157-p Phosphorylation SGSYSSLsPNPLNSR Q13490 Y177-p Phosphorylation SSSRTNPySYAMSTE Q13490 S253-p Phosphorylation NCPFLENsLETLRFS Q13490 S554-p Phosphorylation YIPTEDVsGLsLEEQ Q13490 S557-p Phosphorylation TEDVsGLsLEEQLRR Q13490 S580-p Phosphorylation VCMDKEVsVVFIPCG Q13490 K19-ub Ubiquitination GPSYQNIkSIMEDST Q13490 K36-ub Ubiquitination SDWTNSNkQKMkYDF Q13490 K40-ub Ubiquitination NSNkQKMkYDFSCEL Q13490 K126-ub Ubiquitination ASLGSTSkNTSPMRN Q13490 K226-ub Ubiquitination ACFACGGkLSNWEPk Q13490 K233-ub Ubiquitination kLSNWEPkDDAMSEH Q13490 K305-ub Ubiquitination VGRNDDVkCFCCDGG Q13490 K340-ub Ubiquitination CEFLIRMkGQEFVDE Q13490 K410-ub Ubiquitination GFNRDLVkQTVQSkI Q13490 K416-ub Ubiquitination VkQTVQSkILTTGEN Q13490 K425-ub Ubiquitination LTTGENYkTVNDIVS Q13490 K441-ub Ubiquitination LLNAEDEkREEEkEk Q13490 K446-ub Ubiquitination DEkREEEkEkQAEEM Q13490 K448-ub Ubiquitination kREEEkEkQAEEMAS Q13490 K537-ub Ubiquitination EIDSTLYkNLFVDKN Q13490 K546-ub Ubiquitination LFVDKNMkYIPTEDV

PTM - dbPTM UniProt ID Position Code Type Resources References Q13490 140 S Phosphorylation PhosphoELM.10011 18669648 Q13490 147 S Phosphorylation PhosphoELM.10011 18669648 Q13490 157 S Phosphorylation PhosphoELM.10011 18669648 Q13490 126 K Ubiquitylation Phosphositeplus.1010730 21890473 Q13490 19 K Ubiquitylation Phosphositeplus.1010730 20972266 Q13490 226 K Ubiquitylation Phosphositeplus.1010730 21890473 Q13490 233 K Ubiquitylation Phosphositeplus.1010730 20972266;21890473;21906983 Q13490 340 K Ubiquitylation Phosphositeplus.1010730 21906983 Q13490 36 K Ubiquitylation Phosphositeplus.1010730 21890473 Q13490 40 K Ubiquitylation Phosphositeplus.1010730 21890473 Q13490 410 K Ubiquitylation Phosphositeplus.1010730 21906983 Q13490 416 K Ubiquitylation Phosphositeplus.1010730 21890473 Q13490 425 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q13490 441 K Ubiquitylation Phosphositeplus.1010730 20972266;21906983 Q13490 446 K Ubiquitylation Phosphositeplus.1010730 21906983 Q13490 448 K Ubiquitylation Phosphositeplus.1010730 21906983 Q13490 537 K Ubiquitylation Phosphositeplus.1010730 21890473 Q13490 140 S Phosphorylation Phosphositeplus.1010730 18669648 Q13490 157 S Phosphorylation Phosphositeplus.1010730 18669648 Q13490 140 S Phosphorylation HPRD 9.0 18669648 Q13490 147 S Phosphorylation HPRD 9.0 18669648 Q13490 157 S Phosphorylation HPRD 9.0 18669648

PTM - HPRD Symbol Position Code Type References BIRC2 140 S Phosphorylation 18669648 BIRC2 147 S Phosphorylation 18669648 BIRC2 157 S Phosphorylation 18669648

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q13490 140 S 18669648 HTP Phosphorylation Q13490 157 S 18669648 HTP Phosphorylation Q13490 147 S 18669648 HTP Phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 329 106826 - K Ubiquitination 18570872 329 106826 - K Ubiquitination 18239673 329 106826 - K Ubiquitination 18230607 329 106826 - K Ubiquitination 16510124 329 106826 - K Ubiquitination 12525502 329 106826 - K Ubiquitination 21113135 329 106826 - K Ubiquitination 22212761 329 106826 - K Ubiquitination 21987572 329 106826 - K Ubiquitination 20972266 329 106826 - K Ubiquitination 21817100 329 106826 - K Ubiquitination 21139048 329 106826 - K Ubiquitination 21890473 329 106826 - K Ubiquitination 21906983 329 106826 - K Ubiquitination 15078891 329 106826 - K Ubiquitination 22505724 329 106826 - K Ubiquitination 21963094 329 106826 - K Ubiquitination 23000965 329 106826 - K Ubiquitination 23524849 329 106826 - K Ubiquitination 25147182 329 106826 - K Ubiquitination 25361076

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID BIRC2 Homo sapiens (Human) 425; 36; 233; 126; 416; 40; 537; 226 "425,TTGENYKTVNDIV; 36,DWTNSNKQKMKYD; 233,LSNWEPKDDAMSE; 126,SLGSTSKNTSPMR; 416,KQTVQSKILTTGE; 40,SNKQKMKYDFSCE; 537,IDSTLYKNLFVDK; 226,CFACGGKLSNWEP" 425:21890473; 36:21890473; 233:21890473; 126:21890473; 416:21890473; 40:21890473; 537:21890473; 226:21890473 BIRC2 Homo sapiens (Human) 410; 425; 441; 19; 340; 36; 233; 446; 126; 416; 537; 226; 448 "410,FNRDLVKQTVQSK; 425,TTGENYKTVNDIV; 441,LNAEDEKREEEKE; 19,PSYQNIKSIMEDS; 340,EFLIRMKGQEFVD; 36,DWTNSNKQKMKYD; 233,LSNWEPKDDAMSE; 446,EKREEEKEKQAEE; 126,SLGSTSKNTSPMR; 416,KQTVQSKILTTGE; 537,IDSTLYKNLFVDK; 226,CFACGGKLSNWEP; 448,REEEKEKQAEEMA" "410:21906983; 425:21890473,21906983; 441:20972266,21906983; 19:20972266; 340:21906983; 36:21890473; 233:20972266,21890473,21906983; 446:21906983; 126:21890473; 416:21890473; 537:21890473; 226:21890473; 448:21906983" BIRC2 Homo sapiens (Human) 425; 36; 233; 126; 416; 40; 537; 226 "425,TTGENYKTVNDIV; 36,DWTNSNKQKMKYD; 233,LSNWEPKDDAMSE; 126,SLGSTSKNTSPMR; 416,KQTVQSKILTTGE; 40,SNKQKMKYDFSCE; 537,IDSTLYKNLFVDK; 226,CFACGGKLSNWEP" 425:21890473; 36:21890473; 233:21890473; 126:21890473; 416:21890473; 40:21890473; 537:21890473; 226:21890473 BIRC2 Homo sapiens (Human) 425; 36; 233; 126; 416; 40; 537; 226 "425,TTGENYKTVNDIV; 36,DWTNSNKQKMKYD; 233,LSNWEPKDDAMSE; 126,SLGSTSKNTSPMR; 416,KQTVQSKILTTGE; 40,SNKQKMKYDFSCE; 537,IDSTLYKNLFVDK; 226,CFACGGKLSNWEP" 425:21890473; 36:21890473; 233:21890473; 126:21890473; 416:21890473; 40:21890473; 537:21890473; 226:21890473