PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus AMBRA1 NUDC 25036637 intact exp GP GP G G GP GP G G GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G RPTOR AMBRA1 23524951 biogrid,dip exp GP GP G P GP G P P G P GP P G G P GP P G GP GP GP GP P G P GP G PRAMEF5 AMBRA1 26186194 biogrid exp PSMB2 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G NES AMBRA1 26496610 biogrid,intact exp G G G GP G GP GP G GP G G G G G GP G G G G G GP G G G G G PSMB5 AMBRA1 25499913 biogrid exp G GP G G G GP G G GP G GP G G G G G GP G P G G G GP G G G GP GP G UBL4A AMBRA1 25499913 biogrid exp GP GP G G G GP G G GP G GP G G G G G GP G P G GP G G G G G GP P G AMBRA1 PSMD13 25499913 biogrid exp GP GP G G GP GP G GP GP G GP G GP G G GP GP G P G GP GP GP GP GP G GP GP G TUBB3 AMBRA1 25499913 biogrid exp GP GP G G GP GP G G GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G CCDC132 AMBRA1 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP STIP1 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G LRRC29 AMBRA1 26186194 biogrid exp P P P G GP UBC AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G AMBRA1 FBXW11 25515538 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSMC5 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G PSMD12 AMBRA1 25499913 biogrid exp GP GP G G G GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G HSPA8 AMBRA1 25499913 biogrid exp P P P P P P P P P P P P P P GABARAP AMBRA1 25215947 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAP1B AMBRA1 20562859 biogrid,intact exp G GP G G G GP G G GP G GP G G G G G GP G P G GP GP G G G G G GP G USP50 AMBRA1 19615732 biogrid,intact exp P P P P P P P P P P P P P P P P P P PSMC4 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G PSMA4 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G TCEB2 AMBRA1 25499913 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G CAMKMT AMBRA1 26186194 biogrid exp G G G G G G G G G G G G G G G G G PSMD3 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G BECN1P1 AMBRA1 23954414 intact exp F12 AMBRA1 26186194 biogrid exp G G G G P G P GP G G G G G G P G GP G G G P G HSPA5 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G DYNC1I1 AMBRA1 20921139 biogrid exp GP G G G G GP G G GP G GP G G G G G GP G P G G G GP GP G G GP G G CUL7 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G PSMD6 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G BAG2 AMBRA1 25499913 biogrid exp GP GP G P GP G GP GP G GP G GP GP GP G P G GP GP GP GP GP GP G AMBRA1 STUB1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G AMBRA1 AMBRA1 20562859 intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G AMBRA1 CISH 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G ULK1 AMBRA1 20921139,23524951 biogrid,dip exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G AMBRA1 ATG3 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G PSMA2 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G CCT4 AMBRA1 25499913 biogrid exp GP GP G G G GP G G GP G GP G G G G G GP G G GP G G G G G GP GP G ACTN1 AMBRA1 25499913 biogrid exp G G G G GP GP G G G G G GP GP G G G GP G G GP G GP GP G G G G G GPS1 AMBRA1 25499913 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF2 AMBRA1 24980959 biogrid exp P P P P GP P P P P P P P P P P P AMBRA1 LRRC42 26186194 biogrid exp G GP G G G GP G GP GP G GP GP G G G GP GP G P G GP GP GP GP GP GP GP G MTOR AMBRA1 23524951 biogrid exp G GP G G G GP G G G G G G GP G G G GP G G G GP G G G G GP G G PSMA7 AMBRA1 25499913 biogrid exp G GP G G G GP G G GP G GP GP G G G GP GP G P G GP G G G GP G GP GP G TBC1D22A AMBRA1 26186194 biogrid exp GP GP G G G GP G GP GP G GP G G G G G GP G P G GP G GP G G G G GP G AMBRA1 BAG5 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G NEDD8 AMBRA1 21145461 innatedb exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G PSMC2 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G CCT2 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G G GP GP G G GP GP G P G GP GP G G GP G GP GP G AMBRA1 TRAF6 25499913,23524951 biogrid,dip exp GP GP G G GP G G GP GP G GP GP GP G G GP G G G GP GP GP G GP G GP GP G PSMA5 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G CCT8 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G UBE2D3 AMBRA1 23974797 biogrid exp GP G G G GP GP G G GP G GP GP GP G G G GP G P G GP GP G GP G G GP GP G HSP90AA1 AMBRA1 25499913 biogrid exp GP GP G G G GP G G GP G G G G G G G GP G G GP G G G G G G GP G ATG13 AMBRA1 23524951 biogrid,dip exp GP G G G G GP G GP GP G GP G GP G G GP GP G P G GP G G G GP G GP GP G RFPL4B AMBRA1 26186194 biogrid exp P P P P P P P P P P P P PSMD8 AMBRA1 25499913 biogrid exp GP GP G G G GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G PSMB3 AMBRA1 25499913 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSMA6 AMBRA1 25499913 biogrid exp P P P P P P P P P P P P P P P P P P PSMA3 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G COPS5 AMBRA1 21145461 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G AMBRA1 SUGT1 25499913 biogrid exp G G G G G G G GP GP G GP G G G G GP G G P G G G G GP GP G GP GP G PSMC1 AMBRA1 25499913 biogrid exp GP GP G G GP GP G G GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G PSMC6 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G DNAJB1 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G AMBRA1 ASB8 26186194,24337577 biogrid exp GP GP G G GP GP G GP G G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G COPS8 AMBRA1 25499913 biogrid exp G G G G G GP G GP G G G G GP G G G GP G G G G G G G G G GP G PSMD2 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G WDR1 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G DDA1 AMBRA1 25499913,19295130,20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G GP GP G P G GP GP GP GP GP G GP GP G HSPD1 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G PSMA1 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G HPS1 AMBRA1 26186194 biogrid exp GP GP G G GP GP G GP GP G GP G GP G G GP GP G P G GP GP GP GP GP G GP GP G AMBRA1 TRIM10 26186194 biogrid exp G G G G G G G G G G G G G G GP G G G G G G GP GP GP GP G CCT3 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G PSMC3 AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G AMBRA1 ATG4B 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G PSMD10 AMBRA1 25499913 biogrid exp GP G G G G GP G G GP G G G GP G G GP GP G P G GP GP GP G GP G GP GP G TUBA1A AMBRA1 25499913 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G DYNLL1 AMBRA1 20921139 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G PARK2 AMBRA1 24879156,21753002 biogrid exp, ortho P GP G P GP G GP GP G GP P P G P GP G P G P GP GP GP P GP G PIK3C3 AMBRA1 20417604,20921139, 25402006, 21836163 innatedb,biogrid exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G P GP G P G GP GP GP GP GP G GP GP G BECN1 AMBRA1 24587252,20417604,20562859,17589504,20711182,25499913,21358617,20921139,23954414,23974797, 25402006 innatedb,hprd,biogrid,mint,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G CUL4A AMBRA1 25499913,19295130,16949367,21145461, 25402006 innatedb,biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G DDB1 AMBRA1 25499913,20562859,16949367, 25402006 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G BCL2 AMBRA1 21358617, 25402006 biogrid,mint,intact exp, pred G G G G GP GP G G GP G GP G G G G G GP G G GP GP G G G G G G G CUL4B AMBRA1 25499913,16949367, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP G G G GP GP G P G GP GP GP GP GP G GP GP G RPGRIP1L AMBRA1 ortho P P P P P P P P P P P G P G P P P P P GP G AMBRA1 AFG3L2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G DCAF6 AMBRA1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G AMBRA1 VPRBP 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G PINK1 AMBRA1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SEH1L AMBRA1 25402006 pred G GP G G GP GP G G GP G G G GP G G GP GP G P G GP GP G G GP G GP GP G ATG16L1 AMBRA1 23023127 pred GP G GP GP G G GP GP G G G GP G G G G G G G G G WDTC1 AMBRA1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G NRBF2 AMBRA1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP G G GP GP G GP GP G PIK3R4 AMBRA1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G SLC27A4 AMBRA1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G SQSTM1 AMBRA1 25402006, 23023127 pred GP GP G G GP G G G GP G GP GP GP G G GP G G P G GP GP GP GP GP G GP GP G ERCC8 AMBRA1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G AMBRA1 MAP1LC3A 23023127 pred G GP G G G GP G G GP G G GP G G G GP GP G P G G G G G GP G G GP G KIAA0226 AMBRA1 25402006 pred GP G G G GP G G G G G G G G G G G G G G G GP G G G G G GP G TLE2 AMBRA1 25402006 pred G GP G G G GP G GP GP G GP G GP G G GP GP G P G GP GP G GP GP G GP GP G RB1CC1 AMBRA1 23023127 pred G GP G G G GP G G GP G GP G GP G G GP GP G P G GP GP GP G GP G GP GP G NBR1 AMBRA1 25402006, 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G DCAF5 AMBRA1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G DDB2 AMBRA1 25402006 pred GP GP G G GP GP G G GP G GP GP GP G G GP GP G P G GP G GP GP G GP GP G DCAF12 AMBRA1 25402006 pred G G G G GP GP G G GP G G G GP G G GP GP G P G G G GP GP GP G GP G G AMBRA1 COPS7B 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G DCAF8 AMBRA1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G PHIP AMBRA1 25402006 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G P G GP GP GP GP GP G GP GP G AMBRA1 KIAA0226L 25402006 pred GP GP G G G GP G P GP G P GP GP G G GP GP G P G GP P GP GP G GP GP G AMBRA1 UVRAG 25402006 pred G G G G G GP G GP G G GP G GP G G G GP G G GP G G G G G GP GP G WDR17 AMBRA1 23023127 pred G GP G P P G P GP P G P ATG14 AMBRA1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G DCAF4 AMBRA1 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G P G GP GP GP G GP G GP GP G PAFAH1B2 AMBRA1 23023127 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP G P G GP GP GP G GP G GP GP G RAB24 AMBRA1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G AMBRA1 DTL 25402006 pred P P G GP P G P P G P G P P P P G G G GP DCAF10 AMBRA1 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G GP G G GP G G AMBRA1 DDIT4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G ATG16L2 AMBRA1 23023127 pred GP G G G G GP G GP GP G GP G G G G G GP G P G GP G G G G G GP GP G RGS19 AMBRA1 23023127 pred GP GP G G GP GP G G GP G GP GP GP G G G GP G P G GP GP GP GP G G GP GP G TRPC4AP AMBRA1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP G GP G GP G GP GP G DCAF11 AMBRA1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G P G GP GP GP GP GP G GP GP G TECPR2 AMBRA1 23023127 pred GP GP G G GP GP G GP G G GP GP GP G G GP GP G P G GP GP G GP GP G GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9C0C7 anti bait coimmunoprecipitation 23524951 - C 3 Q9C0C7 anti tag coimmunoprecipitation 23524951 - C 3 Q8N122 Q9C0C7 anti tag coimmunoprecipitation 23524951 physical association X 2 Q9C0C7 Q9Y4K3 anti tag coimmunoprecipitation 23524951 physical association X 2 Q9C0C7 Q9Y4K3 anti tag coimmunoprecipitation 23524951 physical association X 2 Q9C0C7 anti tag coimmunoprecipitation 23524951 - C 3 Q9C0C7 anti bait coimmunoprecipitation 23524951 physical association X 2 Q9C0C7 anti tag coimmunoprecipitation 23524951 physical association X 2 Q9C0C7 anti tag coimmunoprecipitation 23524951 physical association X 2 Q9C0C7 anti bait coimmunoprecipitation 23524951 physical association X 2 Q9C0C7 anti bait coimmunoprecipitation 23524951 physical association X 2 Q9C0C7 anti tag coimmunoprecipitation 23524951 physical association X 2 Q9C0C7 O75143 anti tag coimmunoprecipitation 23524951 physical association X 2 Q9C0C7 anti tag coimmunoprecipitation 20562859 physical association C 7 Q9C0C7 anti tag coimmunoprecipitation 20562859 physical association C 7 Q9C0C7 anti tag coimmunoprecipitation 19615732 physical association C 22 Q9C0C7 anti tag coimmunoprecipitation 23954414 association C 5 Q9C0C7 anti tag coimmunoprecipitation 20562859 physical association C 42 Q9C0C7 anti tag coimmunoprecipitation 22190034 association C 18 Q9C0C7 anti tag coimmunoprecipitation 23954414 association C 6 Q9C0C7 anti tag coimmunoprecipitation 20562859 physical association C 24 Q9C0C7 tandem affinity purification 20360068 physical association C 32 Q9C0C7 anti bait coimmunoprecipitation 21358617 association C 3 Q9C0C7 tandem affinity purification 20360068 physical association C 12 Q9C0C7 anti bait coimmunoprecipitation 23974797 association C 5 Q7CGH9 Q9C0C7 two hybrid pooling approach 20711500 physical association X 2 A0A024R2B3 Q9C0C7 anti tag coimmunoprecipitation 21358617 physical association X 2 A0A024R2B3 Q9C0C7 fluorescence microscopy 21358617 colocalization X 2 A0A024R2B3 Q9C0C7 anti bait coimmunoprecipitation 21358617 physical association X 2 A0A024R2B3 Q9C0C7 fluorescent resonance energy transfer 21358617 physical association X 2 A0A024R2B3 Q9C0C7 cross-linking study 21358617 covalent binding X 2 A0A024R2B3 Q9C0C7 fluorescence microscopy 21358617 colocalization X 2 A0A024R2B3 Q9C0C7 anti bait coimmunoprecipitation 21358617 physical association X 2 A0A024R2B3 Q9C0C7 anti tag coimmunoprecipitation 21358617 physical association X 2 A0A024R2B3 Q9C0C7 anti bait coimmunoprecipitation 21358617 physical association X 2 Q8ZIE7 Q9C0C7 two hybrid pooling approach 20711500 physical association X 2 P12504 Q9C0C7 pull down 22190034 physical association X 2 Q7CJF3 Q9C0C7 two hybrid pooling approach 20711500 physical association X 2 Q9Y266 Q9C0C7 luminescence based mammalian interactome mapping 25036637 physical association X 2 Q9C0C7 anti tag coimmunoprecipitation 22190034 association C 16 Q9C0C7 pull down 22190034 association C 12 Q9C0C7 anti tag coimmunoprecipitation 23954414 association C 5 Q9C0C7 pull down 22190034 association C 11 Q81VT8 Q9C0C7 two hybrid pooling approach 20711500 physical association X 2 A0A024R1X5 Q9C0C7 anti bait coimmunoprecipitation 21358617 physical association X 2 A0A024R1X5 Q9C0C7 anti tag coimmunoprecipitation 21358617 physical association X 2 A0A024R1X5 Q9C0C7 anti tag coimmunoprecipitation 21358617 physical association X 2 A0A024R1X5 Q9C0C7 anti bait coimmunoprecipitation 23974797 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBE2D3 AMBRA1 MI:0004(affinity chromatography technology) 23974797 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_289528 prey bait USP50 AMBRA1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 19615732 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_100681|BIOGRID_120540 bait|bait prey|prey CD302 AMBRA1 MI:0004(affinity chromatography technology) 20921139 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_212227 bait prey AMBRA1 DDA1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19295130,20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(biogrid)|(biogrid) UniProt_106944|BIOGRID_221654|BIOGRID_124980|BIOGRID_125163 bait|prey|bait|prey prey|bait|prey|bait MTOR AMBRA1 MI:0004(affinity chromatography technology) 23524951 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_281067 bait prey AMBRA1 SLC25A10 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20921139 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_212232|BIOGRID_212228 prey|prey bait|bait UBC AMBRA1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12938929,16196087,21139048,21890473,21906983,21963094,21987572,22053931,22505724,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_142722|BIOGRID_174216|BIOGRID_170074|BIOGRID_266801|BIOGRID_166279|BIOGRID_167102|BIOGRID_162805|BIOGRID_270018|BIOGRID_179337|BIOGRID_224564 bait|bait|bait|bait|bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey|prey|prey|prey|prey ATG13 AMBRA1 MI:0004(affinity chromatography technology) 23524951 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_281059 bait prey RPTOR AMBRA1 MI:0004(affinity chromatography technology) 23524951 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_281068 bait prey CUL4A AMBRA1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16949367,19295130,21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_221320|BIOGRID_202935|BIOGRID_122891 bait|bait|prey prey|prey|bait BCL2 AMBRA1 MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0004(affinity chromatography technology)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0004(affinity chromatography technology)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy) 21358617 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0195(covalent binding)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(intact)|(intact)|(biogrid)|(intact)|(intact) UniProt_113289|UniProt_113290|UniProt_113291|UniProt_113302|UniProt_113299|UniProt_113298|BIOGRID_213240|UniProt_113297|UniProt_113300|BIOGRID_213238|UniProt_113292|UniProt_113295 neutral component|prey|prey|prey|prey|neutral component|prey|prey|neutral component|bait|bait|prey neutral component|bait|bait|bait|bait|neutral component|bait|bait|neutral component|prey|prey|bait AMBRA1 ASB8 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309736 prey bait UBD AMBRA1 MI:0004(affinity chromatography technology) 22797925 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_226410 bait prey CUL4B AMBRA1 MI:0004(affinity chromatography technology) 16949367 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_122907 prey bait BECN1 AMBRA1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0416(fluorescence microscopy)|MI:0004(affinity chromatography technology)|MI:0416(fluorescence microscopy)|MI:0493(in vivo)|MI:0416(fluorescence microscopy)|MI:0004(affinity chromatography technology)|MI:0416(fluorescence microscopy)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 17589504,20562859,21358617,23954414,23974797 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid)|(intact)|MI:0468(hprd)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(intact) BIOGRID_289527|BIOGRID_289529|BIOGRID_125061|UniProt_113296|BIOGRID_289530|UniProt_113301|HPRD_32326|UniProt_113293|BIOGRID_213241|UniProt_113295|UniProt_106951|UniProt_131029|UniProt_176881 prey|bait|bait|bait|bait|bait|-|bait|bait|prey|prey|bait|bait bait|prey|prey|prey|prey|prey|-|prey|prey|bait|prey|prey|prey AMBRA1 ATG4B MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_106944|BIOGRID_124979 bait|bait prey|prey AMBRA1 TRAF6 MI:0004(affinity chromatography technology) 23524951 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_281064 prey bait COPS5 AMBRA1 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_205046 bait prey MAP1B AMBRA1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_106944|BIOGRID_124977 prey|prey prey|bait AMBRA1 ATG3 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124978|UniProt_106944 bait|prey prey|prey ULK1 AMBRA1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20921139,23524951 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_281056|BIOGRID_281055|BIOGRID_212230 bait|prey|bait prey|bait|prey PARK2 AMBRA1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21753002 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_141842|BIOGRID_141843|BIOGRID_141844 prey|bait|bait bait|prey|prey DDB1 AMBRA1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16949367,20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(biogrid)|(biogrid) UniProt_106944|BIOGRID_122874|BIOGRID_124976|BIOGRID_122845 prey|prey|prey|bait prey|bait|bait|prey

PPI - HINT Gene A Gene B PMID Method Quality PARK2 AMBRA1 21753002,24879156 0004,0004 LC UBC AMBRA1 12938929,21963094,25499913 0096,0004,0004 LC MAP1B AMBRA1 20562859,20562859 0007,0004 HT NES AMBRA1 26496610 0007 HT DCAF7 AMBRA1 27173435 0676 HT DYNLL1 AMBRA1 27173435 0676 HT CUL4A AMBRA1 21145461,16949367,25499913,19295130,16949367,25499913 0004,0096,0415,0004,0004,0004 HT,LC CUL4B AMBRA1 16949367,16949367,25499913,25499913 0004,0096,0415,0004 LC BECN1 AMBRA1 21358617,21358617,20562859,20562859,23974797,23954414 0006,0007,0007,0004,0006,0007 LC,HT DDB1 AMBRA1 16949367,20562859,16949367,20562859,25499913 0004,0007,0096,0004,0004 LC,HT PRAMEF5 AMBRA1 26186194 0004 HT RFPL4B AMBRA1 26186194 0004 HT USP50 AMBRA1 19615732,19615732 0004,0007 HT CAMKMT AMBRA1 26186194 0004 HT Q8IZZ5 AMBRA1 26186194 0004 HT TBC1D22A AMBRA1 26186194 0004 HT LRRC29 AMBRA1 26186194 0004 HT HPS1 AMBRA1 26186194 0004 HT COPS5 AMBRA1 21145461 0004 HT DYNLL2 AMBRA1 27173435 0676 HT VPS50 AMBRA1 26186194 0004 HT DDA1 AMBRA1 20562859,20562859,19295130,25499913 0007,0004,0004,0004 HT,LC AMBRA1 AMBRA1 20562859 0007 HT AMBRA1 Q9H6U9 26496610 0004 HT AMBRA1 ASB8 24337577,26186194 0004,0004 LC,HT AMBRA1 CISH 26186194 0004 HT AMBRA1 ATG3 20562859,20562859 0007,0004 HT AMBRA1 TRIM10 26186194 0004 HT AMBRA1 TRAF6 23524951,23524951,25499913 0007,0004,0004 LC AMBRA1 ATG4B 20562859,20562859 0007,0004 HT AMBRA1 LRRC42 26186194 0004 HT AMBRA1 W0FFG4 20711182,23974797,21358617,23974797,24587252,20562859,23974797,20921139,20711182,25499913 0055,0415,0004,0004,0004,0004,0096,0004,0004,0004 LC,HT MAP1B AMBRA1 20562859,20562859 0007,0004 HT NES AMBRA1 26496610 0007 HT DCAF7 AMBRA1 27173435 0676 HT DYNLL1 AMBRA1 27173435 0676 HT CUL4A AMBRA1 21145461 0004 HT BECN1 AMBRA1 20562859,20562859 0007,0004 HT DDB1 AMBRA1 20562859,20562859 0007,0004 HT PRAMEF5 AMBRA1 26186194 0004 HT RFPL4B AMBRA1 26186194 0004 HT USP50 AMBRA1 19615732,19615732 0004,0007 HT CAMKMT AMBRA1 26186194 0004 HT Q8IZZ5 AMBRA1 26186194 0004 HT TBC1D22A AMBRA1 26186194 0004 HT LRRC29 AMBRA1 26186194 0004 HT HPS1 AMBRA1 26186194 0004 HT COPS5 AMBRA1 21145461 0004 HT DYNLL2 AMBRA1 27173435 0676 HT VPS50 AMBRA1 26186194 0004 HT DDA1 AMBRA1 20562859,20562859 0007,0004 HT AMBRA1 AMBRA1 20562859 0007 HT AMBRA1 Q9H6U9 26496610 0004 HT AMBRA1 ASB8 26186194 0004 HT AMBRA1 CISH 26186194 0004 HT AMBRA1 ATG3 20562859,20562859 0007,0004 HT AMBRA1 TRIM10 26186194 0004 HT AMBRA1 ATG4B 20562859,20562859 0007,0004 HT AMBRA1 LRRC42 26186194 0004 HT AMBRA1 W0FFG4 20562859 0004 HT PARK2 AMBRA1 21753002,24879156 0004,0004 LC UBC AMBRA1 12938929,21963094,25499913 0096,0004,0004 LC CUL4A AMBRA1 16949367,25499913,19295130,16949367,25499913 0096,0415,0004,0004,0004 LC CUL4B AMBRA1 16949367,16949367,25499913,25499913 0004,0096,0415,0004 LC BECN1 AMBRA1 21358617,21358617,23974797,23954414 0006,0007,0006,0007 LC DDB1 AMBRA1 16949367,16949367,25499913 0004,0096,0004 LC DDA1 AMBRA1 19295130,25499913 0004,0004 LC AMBRA1 ASB8 24337577 0004 LC AMBRA1 TRAF6 23524951,23524951,25499913 0007,0004,0004 LC AMBRA1 W0FFG4 20711182,23974797,21358617,23974797,24587252,23974797,20921139,20711182,25499913 0055,0415,0004,0004,0004,0096,0004,0004,0004 LC ULK1 AMBRA1 20921139 0415 LC BCL2 AMBRA1 21358617,21358617,21358617,21358617,21358617,21358617 0030,0004,0006,0007,0416,0055 LC MTOR AMBRA1 23524951 0415 LC PPP2CA AMBRA1 25438055,25438055 0004,0018 LC CUL4A AMBRA1 25499913,25499913 0415,0004 LC CUL4B AMBRA1 25499913,25499913 0415,0004 LC BECN1 AMBRA1 17589504 0018 LC DNCL1 AMBRA1 20921139,20921139 0018,0004 LC RNF2 AMBRA1 24980959,24980959,24980959,24980959 0415,0096,0004,0018 LC AMBRA1 NUDC 25036637 0729 HT AMBRA1 W0FFG4 20711182,23974797,23974797,23974797,20711182 0055,0415,0004,0096,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9C0C7 P57078 AMBRA1 RIPK4 0.126 26972000 Q9C0C7 B4URF5 AMBRA1 PB1 {ECO:0000313|EMBL:ACF54606.1} 0.126 unassigned1333 Q9C0C7 A1A4Y4 AMBRA1 IRGM 0.21 25891078 Q9C0C7 Q5TYX0 AMBRA1 PRAMEF5 {ECO:0000312|HGNC:HGNC:27995} 0.126 26186194 Q9C0C7 Q8N122 AMBRA1 RPTOR 0.21 23524951 Q9NSE2 Q9C0C7 CISH AMBRA1 0.126 26186194 Q9C0C7 O75143 AMBRA1 ATG13 0.21 23524951 Q9Y266 Q9C0C7 NUDC AMBRA1 0.126 25036637 Q9Y546 Q9C0C7 LRRC42 AMBRA1 0.126 26186194 Q9C0C7 Q6ZWI9 AMBRA1 RFPL4B 0.126 26186194 Q9C0C7 Q7CJF3 AMBRA1 LIGA 0.126 20711500 Q9C0C7 P0DM65 AMBRA1 BECN2 0.21 23954414 Q9C0C7 Q7Z624 AMBRA1 CAMKMT 0.126 26186194 Q9C0C7 P00748 AMBRA1 F12 0.126 26186194 Q9C0C7 P01106 AMBRA1 MYC 0.21 25438055 Q9C0C7 P03428 AMBRA1 PB2 0.126 unassigned1333 Q9C0C7 P03431 AMBRA1 PB1 0.126 unassigned1333 Q9Z1Z0 Q9C0C7 USO1 AMBRA1 0.236 26496610 Q9Y4K3 Q9C0C7 TRAF6 AMBRA1 0.309 23524951,25499913 Q9H765 Q9C0C7 ASB8 AMBRA1 0.236 24337577,26186194 Q9C0C7 Q8K1R7 AMBRA1 NEK9 0.236 20360068 Q9C0C7 P46821 AMBRA1 MAP1B 0.236 20562859 Q9C0C7 P63167 AMBRA1 DYNLL1 0.583 20921139,27173435,unassigned1312 Q9C0C7 Q13619 AMBRA1 CUL4A 0.523 25499913,21145461,16949367,19295130 Q9NT62 Q9C0C7 ATG3 AMBRA1 0.236 20562859 Q9Y4P1 Q9C0C7 ATG4B AMBRA1 0.236 20562859 Q9D9Z5 Q9C0C7 DDA1 AMBRA1 0.236 26496610 Q9C0C7 P48681 AMBRA1 NES 0.236 26496610 Q9C0C7 Q70EL3 AMBRA1 USP50 0.236 19615732 Q9C0C7 P63168 AMBRA1 DYNLL1 0.236 20360068 Q9C0C7 P12504 AMBRA1 VIF 0.332 22190034 Q9C0C7 Q9BW61 AMBRA1 DDA1 0.554 20562859,25499913,19295130 Q9C0C7 Q3U1J4 AMBRA1 DDB1 0.416 26496610,20360068 Q9C0C7 Q14457 AMBRA1 BECN1 0.987 20921139,25499913,21358617,20711182,23974797,23954414,24587252,20562859 Q9C0C7 Q99496 AMBRA1 RNF2 0.74 24980959 Q9C0C7 P10415 AMBRA1 BCL2 0.888 21358617 Q9C0C7 Q92902 AMBRA1 HPS1 0.126 26186194 Q9C0C7 Q92905 AMBRA1 COPS5 0.126 21145461 Q9C0C7 Q8WUA7 AMBRA1 TBC1D22A 0.126 26186194 Q9C0C7 P30153 AMBRA1 PPP2R1A 0.376 25438055 Q9C0C7 Q8WV35 AMBRA1 LRRC29 0.126 26186194 Q9C0C7 Q8ZIE7 AMBRA1 DDL 0.126 20711500 Q9C0C7 Q96FJ2 AMBRA1 DYNLL2 0.236 27173435,unassigned1312 Q9C0C7 Q96JG6 AMBRA1 CCDC132 0.126 26186194 Q9C0C7 O00232 AMBRA1 PSMD12 0.126 25499913 Q9C0C7 O14818 AMBRA1 PSMA7 0.126 25499913 Q9C0C7 O43242 AMBRA1 PSMD3 0.126 25499913 Q9C0C7 O60260 AMBRA1 PARK2 0.507 21753002,24879156 Q9C0C7 O75083 AMBRA1 WDR1 0.126 25499913 Q9C0C7 O75385 AMBRA1 ULK1 0.569 20921139,23524951 Q9C0C7 O75832 AMBRA1 PSMD10 0.126 25499913 Q9C0C7 O95166 AMBRA1 GABARAP 0.21 25215947 Q9C0C7 O95816 AMBRA1 BAG2 0.126 25499913 Q9C0C7 P07900 AMBRA1 HSP90AA1 0.126 25499913 Q9C0C7 P0CG48 AMBRA1 UBC 0.126 25499913 Q9C0C7 P10809 AMBRA1 HSPD1 0.126 25499913 Q9C0C7 P11021 AMBRA1 HSPA5 0.126 25499913 Q9C0C7 P11142 AMBRA1 HSPA8 0.126 25499913 Q9C0C7 P11441 AMBRA1 UBL4A 0.126 25499913 Q9C0C7 P12814 AMBRA1 ACTN1 0.126 25499913 Q9C0C7 P17980 AMBRA1 PSMC3 0.126 25499913 Q9C0C7 P25685 AMBRA1 DNAJB1 0.126 25499913 Q9C0C7 P25786 AMBRA1 PSMA1 0.126 25499913 Q9C0C7 P25787 AMBRA1 PSMA2 0.126 25499913 Q9C0C7 P25788 AMBRA1 PSMA3 0.126 25499913 Q9C0C7 P25789 AMBRA1 PSMA4 0.126 25499913 Q9C0C7 P28066 AMBRA1 PSMA5 0.126 25499913 Q9C0C7 P28074 AMBRA1 PSMB5 0.126 25499913 Q9C0C7 P31948 AMBRA1 STIP1 0.126 25499913 Q9C0C7 P35998 AMBRA1 PSMC2 0.126 25499913 Q9C0C7 P43686 AMBRA1 PSMC4 0.126 25499913 Q9C0C7 P48556 AMBRA1 PSMD8 0.126 25499913 Q9C0C7 P49368 AMBRA1 CCT3 0.126 25499913 Q9C0C7 P49720 AMBRA1 PSMB3 0.126 25499913 Q9C0C7 P49721 AMBRA1 PSMB2 0.126 25499913 Q9C0C7 P50990 AMBRA1 CCT8 0.126 25499913 Q9C0C7 P50991 AMBRA1 CCT4 0.126 25499913 Q9C0C7 P60900 AMBRA1 PSMA6 0.126 25499913 Q9C0C7 P61077 AMBRA1 UBE2D3 0.309 23974797 Q9C0C7 P61962 AMBRA1 DCAF7 0.236 27173435,unassigned1312 Q9C0C7 P62191 AMBRA1 PSMC1 0.126 25499913 Q9C0C7 P62195 AMBRA1 PSMC5 0.126 25499913 Q9C0C7 P62333 AMBRA1 PSMC6 0.126 25499913 Q9C0C7 P67775 AMBRA1 PPP2CA 0.569 25438055 Q9C0C7 P78371 AMBRA1 CCT2 0.126 25499913 Q9C0C7 Q13098 AMBRA1 GPS1 0.126 25499913 Q9C0C7 Q13200 AMBRA1 PSMD2 0.126 25499913 Q9C0C7 Q13509 AMBRA1 TUBB3 0.126 25499913 Q9C0C7 Q14999 AMBRA1 CUL7 0.126 25499913 Q9C0C7 Q15008 AMBRA1 PSMD6 0.126 25499913 Q9C0C7 Q15370 AMBRA1 TCEB2 0.126 25499913 Q9C0C7 Q71U36 AMBRA1 TUBA1A 0.126 25499913 Q9C0C7 Q7CGH9 AMBRA1 PARC 0.126 20711500 Q9C0C7 Q81VT8 AMBRA1 RPOB 0.126 20711500 Q9C0C7 Q8NEB9 AMBRA1 PIK3C3 0.21 20921139 Q9C0C7 Q99627 AMBRA1 COPS8 0.126 25499913 Q9C0C7 Q9C0C7 AMBRA1 AMBRA1 0.155 20562859 Q9UL15 Q9C0C7 BAG5 AMBRA1 0.126 25499913 Q9UNE7 Q9C0C7 STUB1 AMBRA1 0.126 25499913 Q9UNM6 Q9C0C7 PSMD13 AMBRA1 0.126 25499913 Q9Y2Z0 Q9C0C7 SUGT1 AMBRA1 0.126 25499913 Q9UDY6 Q9C0C7 TRIM10 AMBRA1 0.126 26186194 Q9UKB1 Q9C0C7 FBXW11 AMBRA1 0.126 25515538 Q9C0C7 B4URF7 AMBRA1 PB2 {ECO:0000256|RULEBASE:RU361246, ECO:0000313|EMBL:ACF54608.1} 0.126 unassigned1333 Q9C0C7 P69720 AMBRA1 VIF 0.126 22190034 Q9C0C7 C5E526 AMBRA1 PB1 {ECO:0000313|EMBL:ACQ84475.1} 0.126 unassigned1333 Q9C0C7 C5E527 AMBRA1 PB2 {ECO:0000256|RULEBASE:RU361246, ECO:0000313|EMBL:ACQ84476.1} 0.126 unassigned1333 Q9C0C7 Q13620 AMBRA1 CUL4B 0.376 25499913,16949367 Q9C0C7 P69721 AMBRA1 VIF 0.126 22190034 Q9C0C7 P69722 AMBRA1 VIF 0.126 22190034 Q9C0C7 P69723 AMBRA1 VIF 0.126 22190034 Q9C0C7 P42345 AMBRA1 MTOR 0.309 23524951 Q9C0C7 Q16531 AMBRA1 DDB1 0.49 20562859,25499913,16949367 Q9C0C7 A8MW95 AMBRA1 BECN1P1 0.21 23954414 Q9C0C7 O14576 AMBRA1 DYNC1I1 0.21 20921139

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 IRGM AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database BECN2 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMD12 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database DYNC1I1 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMA7 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database UBD AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMD3 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PRKAB2 AMBRA1 MI:0362 inference MI:1106 pathways database PARK2 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database USO1 AMBRA1 MI:0362 inference MI:0461 interaction database WDR1 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database ATG13 AMBRA1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ULK1 AMBRA1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PSMD10 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database GABARAP AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database BAG2 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database F12 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database MYC AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AA1 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database UBC AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database BCL2 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database HSPD1 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database HSPA5 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database HSPA8 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database UBL4A AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database ACTN1 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMC3 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database DNAJB1 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMA1 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMA2 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMA3 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMA4 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMA5 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMB5 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PPP2R1A AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database STIP1 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMC2 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database MTOR AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMC4 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database MAP1B AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMD8 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database NES AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database CCT3 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMB3 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMB2 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database CCT8 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database CCT4 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PRKAG1 AMBRA1 MI:0362 inference MI:1106 pathways database PRKAA2 AMBRA1 MI:0362 inference MI:1106 pathways database PSMA6 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D3 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database DCAF7 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMC1 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMC5 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMC6 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database RBX1 AMBRA1 MI:0362 inference MI:0461 interaction database DYNLL1 AMBRA1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PPP2CA AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database CCT2 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database GPS1 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PRKAA1 AMBRA1 MI:0362 inference MI:1106 pathways database PSMD2 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database TUBB3 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database CUL4A AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database CUL4B AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database BECN1 AMBRA1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database CUL7 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PSMD6 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database TCEB2 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database DDB1 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PRAMEF5 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database RPGRIP1L AMBRA1 MI:0362 inference MI:0461 interaction database ATG14 AMBRA1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database RFPL4B AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database USP50 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database TUBA1A AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database CAMKMT AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database RPTOR AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PIK3C3 AMBRA1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database NEK9 AMBRA1 MI:0362 inference MI:0461 interaction database RB1CC1 AMBRA1 MI:0362 inference MI:1106 pathways database TBC1D22A AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database LRRC29 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database SPRYD4 AMBRA1 MI:0362 inference MI:0461 interaction database RUBCN AMBRA1 MI:0362 inference MI:0461 interaction database HPS1 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database COPS5 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database DYNLL2 AMBRA1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database VPS50 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database RNF2 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database PIK3R4 AMBRA1 MI:0362 inference MI:1106 pathways database COPS8 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database ATG101 AMBRA1 MI:0362 inference MI:1106 pathways database DDA1 AMBRA1 MI:0045 experimental interaction detection MI:0461 interaction database AMBRA1 ASB8 MI:0045 experimental interaction detection MI:0461 interaction database AMBRA1 CISH MI:0045 experimental interaction detection MI:0461 interaction database AMBRA1 ATG3 MI:0045 experimental interaction detection MI:0461 interaction database AMBRA1 UVRAG MI:0362 inference MI:0461 interaction database AMBRA1 TRIM10 MI:0045 experimental interaction detection MI:0461 interaction database AMBRA1 PRKAG3 MI:0362 inference MI:1106 pathways database AMBRA1 PRKAG2 MI:0362 inference MI:1106 pathways database AMBRA1 FBXW11 MI:0045 experimental interaction detection MI:0461 interaction database AMBRA1 BAG5 MI:0045 experimental interaction detection MI:0461 interaction database AMBRA1 STUB1 MI:0045 experimental interaction detection MI:0461 interaction database AMBRA1 PSMD13 MI:0045 experimental interaction detection MI:0461 interaction database AMBRA1 NUDC MI:0045 experimental interaction detection MI:0461 interaction database AMBRA1 SUGT1 MI:0045 experimental interaction detection MI:0461 interaction database AMBRA1 PRKAB1 MI:0362 inference MI:1106 pathways database AMBRA1 TRAF6 MI:0045 experimental interaction detection MI:0461 interaction database AMBRA1 ATG4B MI:0045 experimental interaction detection MI:0461 interaction database AMBRA1 LRRC42 MI:0045 experimental interaction detection MI:0461 interaction database