PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RNF8 RNF8 11322894,22980979,22266820 biogrid,intact exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 MAD1L1 25416956 biogrid,intact exp GP P G GP G P P P G G G G GP GP P G G P G GP G P GP RNF8 BCL10 24732096 biogrid exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 CEP44 16189514 hprd,biogrid,mint,intact exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 RPSA 22814251 biogrid exp GP GP P GP P P G P P G P G P G P P P G RNF8 CCDC85B 16189514 hprd,biogrid,mint,intact exp GP GP G G G GP G G GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 TMEM79 25416956,21516116 biogrid,intact exp GP P G G G G G RNF8 XRCC5 22266820 biogrid,dip exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 UBA52 22266820 dip exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G WASL RNF8 25416956,21516116 biogrid,mint,intact exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 JMJD1C 24240613 biogrid,dip exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 SEPT3 25416956 biogrid,intact exp G G G G G GP G G G G G G GP G P G G G G G G G RBFOX2 RNF8 25416956 biogrid,intact exp G GP G G G GP G G GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 MDM2 22493164 biogrid,intact exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 TNF 24980434 biogrid exp G G G G G GP G G GP G G G G G GP GP G GP G G G G GP G GP G G RNF8 MGMT 16226712 biogrid exp GP GP G G G GP G G GP G GP G G G G GP GP G GP G G GP G GP G GP GP G RNF8 SEPT7 23442799 biogrid exp GP GP G G G GP G G GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 YEATS4 22068108 biogrid exp G G G G G G G G G G G G G G G G RNF8 CHD4 doi:10.1038/emboj.2012.104,22531782 biogrid,mint,intact exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 MCPH1 18001825 intact exp GP P G G P P GP P G P P P G P GP GP P RNF8 TNFRSF1A 24980434 biogrid exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 EXOSC2 15231747 hprd,biogrid,i2d,intact exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 UBE2W 19549727 biogrid,intact exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 WRAP53 25512560 biogrid exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 USP16 25305019 biogrid exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G G G GP G GP GP G RNF8 HIST2H2BE 22980979 biogrid exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 PCNA 22980979,18948756 biogrid exp GP GP G G G G G G GP G GP G G G G GP G G GP G G G GP G GP G GP GP G RNF8 HOMEZ 25416956 biogrid,intact exp P P P P P P GP G G P G P P RNF8 PNMA2 25416956,21516116 biogrid,mint,intact exp G GP G G G GP G GP GP G GP G G G GP GP G GP G G P GP GP GP G RNF8 VCP 25416956 biogrid,intact exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 ORC2 18001825 intact exp G G G G G GP G G GP G GP G G G G GP GP G G G G GP G GP G GP GP G RNF8 HERC2 25305019,22508508,22814251,20023648 biogrid exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 UBC 25909880,22266820 biogrid exp GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G KDM4A RNF8 22373579 biogrid exp GP GP G G G GP G GP GP G GP G G G G GP GP G G G G G G G GP G GP GP G RNF8 SEPT8 23442799 biogrid exp G P G GP G GP G P GP GP P G G GP GP P RNF8 HIST2H2AC 22980979 biogrid exp, ortho P P P P P P P P P P P P P RNF8 UBE2N 21911360,19549727,20023648,25909880,23255131,16215985,18678647,22589545,22814251,24732096, 23023127, 21836163 biogrid,intact exp, ortho, pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 RXRA 14981089, 25402006, 21836163 hprd,biogrid exp, pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 TP53BP1 20016603,18001825, 25402006 biogrid,intact exp, pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 ATM 18001825, 25402006 intact exp, pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 MDC1 18001825,25512560,24240613,18006705,18001824, 25402006 hprd,biogrid,intact,dip exp, pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 RAD50 23115235, 25402006 biogrid exp, pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP RNF8 BRCA1 18001825, 25402006, 23023127 intact exp, pred P P G G P P P P GP P P P P P GP RNF8 UBE2E2 11322894,21911360,20023648, 23023127 hprd,biogrid exp, pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 BLM 23708797, 25402006 biogrid exp, pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 UBE2D3 18948756,22373579, 23023127 biogrid exp, pred GP G G G G GP G G GP G GP G G G G G GP G GP G G G G G G G GP GP G RNF8 UBE2E3 11322894, 21836163 hprd,biogrid exp, pred GP GP G G G GP G G GP G GP G G G G GP GP G G G G G G G GP G GP GP G NBN RNF8 18001825,23115235, 25402006 biogrid,intact exp, pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 H2AFX 22980979,18001825,18001824, 25402006, 23023127, 21836163 biogrid,intact exp, pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 UBE2D1 11322894,22266820, 23023127 biogrid exp, pred GP G G G G GP G G GP G GP G G G G G GP G GP G G G G G G G GP GP G RNF8 UBE2D2 19690564, 23023127 intact exp, pred GP G G G G GP G G GP G GP G G G G G GP G GP G G G G G G G GP GP G RNF8 MRE11A 23115235, 25402006 biogrid exp, pred GP P G G P P GP P G G G GP P G P G G P P G GP GP RNF8 UBE2V2 22589545, 23023127 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 UBE2E1 11322894, 23023127, 21836163 hprd,biogrid exp, pred GP GP G G G GP G G GP G GP G G G G GP GP G G G G G G G GP G GP GP G RNF8 CHEK2 22266820, 25402006 biogrid,dip exp, pred GP GP G G P G P GP P GP P G GP G GP P GP GP G RNF8 HIST1H2BJ ortho P P P P P P P P P P P P P TPP1 RNF8 ortho G GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 UBE2V1 23023127 ortho, pred RNF8 BRPF3 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 RLIM 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 RAG1 23023127 pred RNF8 CHD6 23023127 pred G G G G G GP G GP GP G G G G G G G GP G G G G G G G G G G G G RNF8 E2F1 25402006 pred P GP G G G GP G GP GP G GP G G G GP GP G GP G GP GP GP GP G TRIM24 RNF8 25402006 pred G G G G G G G G GP G G G G G G GP G G G G G G GP G GP G GP GP G RNF8 RNF135 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 SP1 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 BIRC7 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G GP G GP G GP GP G RNF8 SMARCA4 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 TDP1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 XIAP 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 RNF7 23023127 pred GP GP G G G GP G G GP G GP G G G G GP GP G GP G G G G G GP G GP GP G RNF8 CBX8 23023127 pred P P P P P P P P P P P P P HNRNPR RNF8 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 PLG 23023127 pred P P G G P P RNF8 UBE2A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 UBE2R2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G G RNF8 FBXO31 23023127 pred GP GP G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 BRE 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 WHSC1L1 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 CD2AP 23023127 pred GP GP G G P G G GP GP G G G G GP GP G GP G G G GP G GP G GP GP RNF8 CHFR 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 UBE2D4 23023127 pred GP G G G G GP G G GP G GP G G G G G GP G GP G G G G G G G GP GP G NR1I2 RNF8 25402006 pred G G G G G RNF8 RBBP8 25402006 pred GP GP G G G GP G G GP G GP G G G G GP GP G GP G G G G G GP G GP GP G RNF8 SMAD3 25402006 pred GP GP G G G GP G G G G G G G G G G GP G GP G G G G G G G G G G RNF8 NR4A1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF103 RNF8 23023127 pred G GP G G G GP G G GP G GP G G G G GP GP G GP G G G G G GP G GP GP G RNF8 NCOA2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 HUWE1 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 PRKCG 23023127 pred G G G G G GP G G G G G G G GP G G G G G G G G RNF8 PAXIP1 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 IFI16 25402006 pred G G G G G GP G G GP G GP G G G G G GP G G G G G G G G G G G G RNF8 CSF2 23023127 pred G G G G G G G G RNF8 NR1I3 25402006 pred P P P P GP G P P G G P G P P GP G RNF8 RNF220 23023127 pred G GP G G G GP G G GP G GP G G G G G GP G GP G G G GP G G G GP G G RNF8 TRIM21 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 FGF19 23023127 pred P P P P P P P P P P P P P RNF8 RNF2 23023127 pred P P P GP P P P P P P P RNF8 CALM1, CALM2, CALM3 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G ADAP1 RNF8 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G CLOCK RNF8 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 VPS4A 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G UBE2C RNF8 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 NR1H2 25402006 pred GP GP G G G GP G G GP G GP G G G G GP GP G GP G G G G G GP G GP GP G RNF8 POLR2A 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G EREG RNF8 23023127 pred P G G P P P P P P G P P P P P RNF8 BMI1 23023127 pred P P P P P P P P P P P P P RNF8 THRB 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 NPAS2 25402006 pred GP GP G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 CUL4A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J 25402006 pred P GP G G P GP P P P P P G GP G P G P P RNF8 KAT2A 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G G G GP G GP GP G RNF8 UBE2G2 23023127 pred GP GP G G G GP G G GP G GP G G G G GP GP G GP G G G G G GP G GP GP G RNF8 ESR1 25402006 pred GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G KLK8 RNF8 23023127 pred GP G G G G G G G G G GP G G G G G G G G G G G G G G G G G RNF8 RPS3 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 BRCC3 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 TP53 25402006 pred G G G G G G G G G G G G G G G GP G G G G G G G G GP G G GP G NCOR1 RNF8 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 CETN1 23023127 pred GP GP G G G GP G G GP G GP G G G GP GP G GP G G GP G GP G GP GP G RNF8 TDRD1 23023127 pred P P P P P P P P P P P P GP RNF8 CHD7 23023127 pred GP G G G G GP G G GP G GP G G G G GP GP G GP G G G G G GP G GP GP G PIAS1 RNF8 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 SLX1A, SLX1B 23023127 pred P P P P P P P P P P P P P RNF8 NLRP2 25402006 pred P P G P G P GP G GP G G G GP GP G GP G G G GP GP G GP GP RNF8 BRIP1 25402006 pred P G G P P GP P GP P P P P P GP RNF8 RARA 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 BARD1 25402006 pred P G G P P GP P G G GP P G P G P G P G GP GP G RNF8 RNF168 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 PIAS4 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G RNF8 SH3RF1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 NCOA3 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 FAM175A 25402006 pred G GP G G G G G G GP G G G G G G GP G G G G G G G G GP G GP GP G RNF8 PRKCB 23023127 pred GP GP G G G GP G G GP G GP G G G G G GP G GP G G G GP G G G GP GP G RNF8 BRD8 25402006 pred P P G G P P P P P P GP P P P GP RNF8 NASP 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 NR1H3 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 UBE2B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FGF10 RNF8 23023127 pred P P P P P P P P GP P P P P RNF8 IL2 23023127 pred P P P P P P P P P P P RNF8 SHC1 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 PPP5C 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 ARAP1 23023127 pred GP GP G G G GP G G GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 PCGF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 TRIM17 23023127 pred P P P P P P P P P P P P GP RNF8 UIMC1 25402006 pred G G G G G G G GP GP G GP G G G G GP G G G G G G G G GP G GP GP G RNF8 SKAP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 NONO 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 UBE2F 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 25402006 pred P P P P P P P P P P P P P RNF8 RING1 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 TRRAP 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 RNF151 23023127 pred P G G G GP GP GP GP G G GP G G G G G GP RNF8 RAD51 25402006 pred P P G G P G P GP P G GP GP G GP G P GP GP GP RNF8 RARB 25402006 pred GP G G G G GP G G GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 RARG 25402006 pred GP GP G G G GP G GP GP G GP G G G G P GP G P G G G GP G P G GP GP G RNF8 THRA 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 BAZ1B 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 NR1H4 25402006 pred P GP P P GP GP G G GP P G GP G GP G GP P P RNF8 GLI1 23023127 pred GP G G G P G G GP P G GP GP G P G GP GP GP G RNF8 STUB1 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 UBOX5 23023127 pred GP GP G G G GP G GP P G G G G G G P GP G G G G G GP GP G GP G G RNF8 NR4A2 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G GP G GP G GP P G RNF8 CREBBP 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 USP28 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 RNF115 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 TTC3 23023127 pred P P P P P RNF8 BRAP 25402006 pred P P G G P GP P P G GP P P G G GP G GP P GP RNF8 UBE4A 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 MED1 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 UBE2H 23023127 pred GP GP G G G GP G GP G G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 PLEKHA1 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G RNF8 TRAF6 23023127 pred GP GP G G G G G GP GP G GP G G G G GP G G G G G G GP G GP G GP GP G RNF8 DTX3L 23023127 pred GP GP G G G GP G GP GP G GP G G G G GP GP G G G G G GP G GP G GP GP G RNF8 RAD18 25402006, 23023127 pred P P P G P P G P G P RNF8 PPARA 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G RNF8 TOP2A 25402006 pred P P G G GP G GP G GP G GP GP RNF8 NHLRC1 23023127 pred RNF8 TOPBP1 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q13868 O76064 - 15231747 - X 2 Q16777 O76064 enzymatic study 21706008 direct interaction X 2 Q16777 O76064 enzymatic study 22980979 direct interaction X 2 A0A024R2P0 O76064 two hybrid 22814251 direct interaction X 2 A0A024R2P0 O76064 affinity chromatography technology 22814251 physical association X 2 A0A024R2P0 O76064 affinity chromatography technology 22814251 physical association X 2 A0A024R2P0 O76064 imaging technique 22814251 colocalization X 2 O95619 O76064 two hybrid 22068108 direct interaction X 2 O95619 O76064 two hybrid 22068108 direct interaction X 2 P16104 O76064 enzymatic study 22980979 direct interaction X 2 Q12888 O76064 imaging technique 20016603 colocalization X 2 A0A087WW00 O76064 pull down 11322894 direct interaction X 2 A0A087WW00 O76064 pull down 22266820 direct interaction X 2 Q13868 O76064 two hybrid 15231747 direct interaction X 2 O00401 O76064 two hybrid 25416956 direct interaction X 2 Q9UH03-2 O76064 two hybrid 25416956 direct interaction X 2 F1D8Q5 O76064 two hybrid 14981089 direct interaction X 2 F1D8Q5 O76064 pull down 14981089 direct interaction X 2 F1D8Q5 O76064 fluorescent resonance energy transfer 14981089 direct interaction X 2 O95714 O76064 two hybrid 22814251 direct interaction X 2 O95714 O76064 affinity chromatography technology 25305019 physical association X 2 O95714 O76064 affinity chromatography technology 20023648 physical association X 2 O95714 O76064 affinity chromatography technology 20023648 physical association X 2 O95714 O76064 affinity chromatography technology 20023648 physical association X 2 O95714 O76064 affinity chromatography technology 22508508 physical association X 2 B4DEE8 O76064 affinity chromatography technology 16226712 physical association X 2 Q14839 O76064 affinity chromatography technology 22531782 physical association X 2 Q14839 O76064 affinity chromatography technology 22531782 physical association X 2 Q14839 O76064 pull down 22531782 direct interaction X 2 Q00987 O76064 two hybrid 22493164 direct interaction X 2 O76064 affinity chromatography technology 23442799 physical association X 2 P55854 O76064 affinity chromatography technology 25391492 physical association X 2 O95999 O76064 affinity chromatography technology 24732096 physical association X 2 Q9Y5T5-5 O76064 affinity chromatography technology 25305019 physical association X 2 Q9Y5T5-5 O76064 affinity chromatography technology 25305019 physical association X 2 Q14676 O76064 affinity chromatography technology 24240613 physical association X 2 Q14676 O76064 pull down 18001825 direct interaction X 2 Q14676 O76064 affinity chromatography technology 18001824 physical association X 2 Q14676 O76064 affinity chromatography technology 18001824 physical association X 2 Q14676 O76064 pull down 18006705 direct interaction X 2 Q14676 O76064 affinity chromatography technology 18006705 physical association X 2 Q15652-3 O76064 pull down 24240613 direct interaction X 2 Q15652-3 O76064 affinity chromatography technology 24240613 physical association X 2 P55072 O76064 two hybrid 25416956 direct interaction X 2 O76064 O76064 enzymatic study 22266820 direct interaction X 2 O76064 A0A024R2Q2 pull down 11322894 direct interaction X 2 O76064 A0A024R2K3 pull down 11322894 direct interaction X 2 O76064 Q13404 pull down 21706008 direct interaction X 2 O76064 Q92878 affinity chromatography technology 23115235 physical association X 2 O76064 affinity chromatography technology 23115235 physical association X 2 O76064 affinity chromatography technology 23442799 physical association X 2 O76064 two hybrid 25416956 direct interaction X 2 O76064 Q8IX15 two hybrid 25416956 direct interaction X 2 O76064 A0A024R2Q2 two hybrid 11322894 direct interaction X 2 O76064 A0A024R2K3 two hybrid 11322894 direct interaction X 2 O76064 O76064 enzymatic study 11322894 direct interaction X 2 O76064 A0A024R2Q2 affinity chromatography technology 20023648 physical association X 2 O76064 A0A024R2Q2 affinity chromatography technology 21911360 physical association X 2 O76064 A0A024R2Q2 affinity chromatography technology 21911360 physical association X 2 Q15834 O76064 two hybrid 16189514 direct interaction X 2 P61077-3 O76064 pull down 22373579 direct interaction X 2 P61077-3 O76064 pull down 18948756 direct interaction X 2 G8HBH2 O76064 affinity chromatography technology 22405594 physical association X 2 G8HBH2 O76064 unspecified method 22405594 direct interaction X 2 G8HBH2 O76064 affinity chromatography technology 20075863 physical association X 2 G8HBH2 O76064 enzymatic study 20075863 direct interaction X 2 Q9UL42 O76064 two hybrid 25416956 direct interaction X 2 Q9C0F1 O76064 two hybrid 16189514 direct interaction X 2 P01375 O76064 affinity chromatography technology 24980434 physical association X 2 Q9BSE2 O76064 two hybrid 25416956 direct interaction X 2 O60934 O76064 affinity chromatography technology 23115235 physical association X 2 O60934 O76064 enzymatic study 23115235 direct interaction X 2 Q16778 O76064 enzymatic study 21706008 direct interaction X 2 Q16778 O76064 enzymatic study 22980979 direct interaction X 2 Q969T4 O76064 pull down 11322894 direct interaction X 2 Q969T4 O76064 two hybrid 11322894 direct interaction X 2 O75164 O76064 enzymatic study 22373579 direct interaction X 2 A0M8W4 O76064 pull down 22589545 direct interaction X 2 P0CG48 O76064 affinity chromatography technology 20656690 physical association X 2 P0CG48 O76064 affinity chromatography technology 16215985 physical association X 2 P0CG48 O76064 affinity chromatography technology 24634510 physical association X 2 P0CG48 O76064 enzymatic study 22266820 direct interaction X 2 P0CG48 O76064 affinity chromatography technology 22266820 physical association X 2 P0CG48 O76064 affinity chromatography technology 21911360 physical association X 2 P0CG48 O76064 affinity chromatography technology 21139048 physical association X 2 P0CG48 O76064 affinity chromatography technology 21906983 physical association X 2 P13010 O76064 affinity chromatography technology 22266820 physical association X 2 P61088 O76064 pull down 22589545 direct interaction X 2 P61088 O76064 two hybrid 16215985 direct interaction X 2 P61088 O76064 affinity chromatography technology 16215985 physical association X 2 P61088 O76064 two hybrid 18678647 direct interaction X 2 P61088 O76064 pull down 21706008 direct interaction X 2 P61088 O76064 affinity chromatography technology 23255131 physical association X 2 P61088 O76064 two hybrid 22814251 direct interaction X 2 P61088 O76064 affinity chromatography technology 24732096 physical association X 2 P61088 O76064 two hybrid 19549727 direct interaction X 2 P61088 O76064 affinity chromatography technology 20023648 physical association X 2 P61088 O76064 affinity chromatography technology 21911360 physical association X 2 P61088 O76064 affinity chromatography technology 21911360 physical association X 2 P12004 O76064 enzymatic study 18948756 direct interaction X 2 P12004 O76064 affinity chromatography technology 18948756 physical association X 2 P12004 O76064 enzymatic study 22980979 direct interaction X 2 O76064 affinity chromatography technology 22266820 physical association X 2 O76064 enzymatic study 22266820 direct interaction X 2 O76064 Q15843 affinity chromatography technology 24634510 physical association X 2 O76064 O43251-9 two hybrid 25416956 direct interaction X 2 O76064 Q96FI0 two hybrid 19549727 direct interaction X 2 P19438 O76064 affinity chromatography technology 24980434 physical association X 2 P19438 O76064 affinity chromatography technology 24980434 physical association X 2 P54132 O76064 enzymatic study 23708797 direct interaction X 2 Q14676 O76064 anti bait coimmunoprecipitation 24240613 physical association X 2 Q14676 O76064 anti tag coimmunoprecipitation 24240613 physical association X 2 O96017 O76064 pull down 22266820 physical association X 2 Q15652 O76064 anti bait coimmunoprecipitation 24240613 physical association X 2 Q15652 O76064 pull down 24240613 physical association X 2 P13010 O76064 pull down 22266820 physical association X 2 O76064 P62987 pull down 22266820 physical association X 2 O76064 fluorescence microscopy 20075863 colocalization C 3 P16104 O76064 confocal microscopy 18001824 colocalization X 2 P16104 O76064 fluorescence microscopy 18001825 colocalization X 2 P16104 O76064 fluorescence microscopy 18001825 colocalization X 2 Q12888 O76064 fluorescence microscopy 18001825 colocalization X 2 Q12888 O76064 fluorescence microscopy 18001825 colocalization X 2 Q8IX15-3 O76064 two hybrid prey pooling approach 25416956 physical association X 2 Q8IX15-3 O76064 two hybrid array 25416956 physical association X 2 Q8IX15-3 O76064 validated two hybrid 25416956 physical association X 2 Q13868 O76064 two hybrid 15231747 physical association X 2 O00401 O76064 two hybrid 21516116 physical association X 2 O00401 O76064 two hybrid prey pooling approach 25416956 physical association X 2 O00401 O76064 two hybrid array 25416956 physical association X 2 O00401 O76064 validated two hybrid 25416956 physical association X 2 Q9UH03 O76064 two hybrid prey pooling approach 25416956 physical association X 2 Q9UH03 O76064 two hybrid array 25416956 physical association X 2 Q9UH03 O76064 validated two hybrid 25416956 physical association X 2 Q9Y6D9 O76064 two hybrid prey pooling approach 25416956 physical association X 2 Q9Y6D9 O76064 two hybrid array 25416956 physical association X 2 Q9Y6D9 O76064 validated two hybrid 25416956 physical association X 2 Q14839 O76064 anti tag coimmunoprecipitation 22531782 physical association X 2 Q00987 O76064 two hybrid array 22493164 physical association X 2 Q14676 O76064 anti tag coimmunoprecipitation 18001824 physical association X 2 Q14676 O76064 anti tag coimmunoprecipitation 18001824 physical association X 2 Q14676 O76064 anti tag coimmunoprecipitation 18001824 physical association X 2 Q14676 O76064 anti bait coimmunoprecipitation 18001824 physical association X 2 Q14676 O76064 confocal microscopy 18001824 colocalization X 2 Q14676 O76064 pull down 18001825 physical association X 2 Q14676 O76064 fluorescence microscopy 18001825 colocalization X 2 Q14676 O76064 pull down 18001825 physical association X 2 Q14676 O76064 pull down 18001825 physical association X 2 Q14676 O76064 pull down 18001825 physical association X 2 Q14676 O76064 isothermal titration calorimetry 18001825 direct interaction X 2 P55072 O76064 two hybrid prey pooling approach 25416956 physical association X 2 P55072 O76064 two hybrid array 25416956 physical association X 2 P55072 O76064 validated two hybrid 25416956 physical association X 2 O43251 O76064 two hybrid prey pooling approach 25416956 physical association X 2 O43251 O76064 two hybrid array 25416956 physical association X 2 O43251 O76064 validated two hybrid 25416956 physical association X 2 O76064 P62837 two hybrid array 19690564 physical association X 2 O76064 O76064 x ray scattering 22980979 direct interaction Y 1 Q15834 O76064 two hybrid pooling approach 16189514 physical association X 2 Q8NEM0 O76064 fluorescence microscopy 18001825 colocalization X 2 P08393 O76064 tandem affinity purification 20075863 physical association X 2 P08393 O76064 fluorescence microscopy 20075863 colocalization X 2 P38398 O76064 fluorescence microscopy 18001825 colocalization X 2 P38398 O76064 fluorescence microscopy 18001825 colocalization X 2 Q9UL42 O76064 two hybrid 21516116 physical association X 2 Q9UL42 O76064 two hybrid prey pooling approach 25416956 physical association X 2 Q9UL42 O76064 two hybrid array 25416956 physical association X 2 Q9UL42 O76064 validated two hybrid 25416956 physical association X 2 Q9C0F1 O76064 two hybrid pooling approach 16189514 physical association X 2 Q9BSE2 O76064 two hybrid prey pooling approach 25416956 physical association X 2 Q9BSE2 O76064 two hybrid array 25416956 physical association X 2 Q9BSE2 O76064 validated two hybrid 25416956 physical association X 2 O60934 O76064 fluorescence microscopy 18001825 colocalization X 2 A0A024R3C7 O76064 fluorescence microscopy 18001825 colocalization X 2 Q7CJX4 O76064 two hybrid pooling approach 20711500 physical association X 2 P61088 O76064 two hybrid array 19549727 physical association X 2 P27661 O76064 fluorescence microscopy 18001825 colocalization X 2 O76064 A0A024R411 anti bait coimmunoprecipitation 18001825 physical association X 2 Q96B02 O76064 two hybrid array 19549727 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B RNF8 MRE11A MI:0004(affinity chromatography technology) 23115235 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_248520 prey bait RNF8 RPSA MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 22814251 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_260529|BIOGRID_260534|BIOGRID_260533|BIOGRID_260532 bait|prey|bait|prey prey|bait|prey|bait RNF8 RXRA MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0493(in vivo)|MI:0018(two hybrid) 14981089 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|-|MI:0407(direct interaction) (biogrid)|(biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_86937|BIOGRID_86936|HPRD_2719|BIOGRID_86935 prey|prey|-|prey bait|bait|-|bait RNF8 CHEK2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22266820 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_192509|BIOGRID_192508 bait|bait prey|prey RNF8 UBE2D2 MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_102713 prey bait NBN RNF8 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0416(fluorescence microscopy) 18001825,23115235 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization) (biogrid)|(biogrid)|(intact) BIOGRID_248523|BIOGRID_248521|UniProt_93669 prey|bait|neutral component bait|prey|neutral component RNF8 YEATS4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22068108 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_194073|BIOGRID_194076 prey|bait bait|prey RNF8 HERC2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 20023648,22508508,22814251 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_148171|BIOGRID_148173|BIOGRID_148172|BIOGRID_184786|BIOGRID_260531 bait|prey|bait|bait|bait prey|bait|prey|prey|prey RNF8 UBE2E1 MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid) 11322894 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0407(direct interaction) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_11721|BIOGRID_92733|BIOGRID_221447 -|prey|bait -|bait|prey RNF8 UBE2D3 MI:0004(affinity chromatography technology)|MI:0415(enzymatic study) 18948756,22373579 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_225640|BIOGRID_225664 bait|bait prey|prey RNF8 UBE2N MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 16215985,18678647,19549727,20023648,21706008,21911360,22589545,22814251,23255131 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact) BIOGRID_225681|BIOGRID_260530|BIOGRID_154336|BIOGRID_194168|BIOGRID_248136|BIOGRID_188052|BIOGRID_124214|BIOGRID_194173|BIOGRID_208285|BIOGRID_148176|BIOGRID_154337|UniProt_101111 bait|bait|prey|prey|prey|bait|prey|prey|bait|prey|bait|prey prey|prey|bait|bait|bait|prey|bait|bait|prey|bait|prey|bait RNF8 UBE2D1 MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 11322894,22266820 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_225662|BIOGRID_221446 bait|bait prey|prey RNF8 CHFR MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21706008 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0794(synthetic genetic interaction defined by inequality)|MI:0799(additive genetic interaction defined by inequality) (biogrid)|(biogrid) BIOGRID_194859|BIOGRID_194858 prey|prey bait|bait RNF8 UBE2E2 MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology) 11322894,20023648,21911360 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) HPRD_14430|BIOGRID_154340|BIOGRID_148177|BIOGRID_221444|BIOGRID_92731|BIOGRID_154339 -|prey|prey|bait|prey|bait -|bait|bait|prey|bait|prey RNF8 MDC1 MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0416(fluorescence microscopy)|MI:0663(confocal microscopy)|MI:0663(confocal microscopy)|MI:0415(enzymatic study)|MI:0096(pull down)|MI:0416(fluorescence microscopy)|MI:0492(in vitro)|MI:0416(fluorescence microscopy)|MI:0415(enzymatic study)|MI:0416(fluorescence microscopy)|MI:0004(affinity chromatography technology)|MI:0663(confocal microscopy)|MI:0416(fluorescence microscopy)|MI:0663(confocal microscopy)|MI:0663(confocal microscopy)|MI:0416(fluorescence microscopy) 18001824,18001825,18006705,24240613 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(intact)|(intact)|(intact)|(biogrid)|(biogrid)|(intact)|MI:0468(hprd)|(intact)|(biogrid)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact) BIOGRID_136258|BIOGRID_136259|UniProt_93681|UniProt_92898|UniProt_92899|BIOGRID_140819|BIOGRID_297176|UniProt_93677|HPRD_33297|UniProt_93678|BIOGRID_140820|UniProt_93679|BIOGRID_136260|UniProt_92903|UniProt_93668|UniProt_92901|UniProt_92900|UniProt_93676 bait|bait|neutral component|bait|prey|bait|bait|bait|-|prey|prey|bait|prey|neutral component|neutral component|bait|prey|bait prey|prey|neutral component|prey|bait|prey|prey|prey|-|bait|bait|prey|bait|neutral component|neutral component|prey|bait|prey RNF8 CHD4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 22531782 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(intact) BIOGRID_184700|BIOGRID_184702|BIOGRID_184701|UniProt_124130 bait|prey|prey|bait prey|bait|bait|prey RNF8 UBE2E3 MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid) 11322894 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0407(direct interaction) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_12912|BIOGRID_92735|BIOGRID_221445 -|prey|bait -|bait|prey RNF8 UBE2W MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101167|BIOGRID_124215 prey|prey bait|bait RNF8 BLM MI:0415(enzymatic study) 23708797 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_281277 bait prey RNF8 EXOSC2 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231747 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0407(direct interaction) (intact)|MI:0468(hprd)|(biogrid) UniProt_76761|HPRD_10533|BIOGRID_289853 prey|-|prey bait|-|bait RNF8 UBE2V1 MI:0004(affinity chromatography technology) 21706008 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_225682 bait prey RNF8 ORC2 MI:0416(fluorescence microscopy) 18001825 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_93674 bait prey RNF8 ATM MI:0416(fluorescence microscopy) 18001825 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (intact) UniProt_93672 neutral component neutral component WASL RNF8 MI:0018(two hybrid) 21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_114704 prey bait RNF8 TP53BP1 MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0428(imaging technique)|MI:0416(fluorescence microscopy) 18001825,20016603,20075863 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization) (intact)|(intact)|(biogrid)|(intact) UniProt_93670|UniProt_103918|BIOGRID_126122|UniProt_93687 neutral component|neutral component|prey|neutral component neutral component|neutral component|bait|neutral component RNF8 BRCA1 MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy) 18001825 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0403(colocalization) (intact)|(intact) UniProt_93671|UniProt_93688 neutral component|neutral component neutral component|neutral component RNF8 NRF1 MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_294605 prey bait RNF8 HIST2H2BE MI:0415(enzymatic study)|MI:0004(affinity chromatography technology) 21706008,22980979 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_252424|BIOGRID_194863 bait|bait prey|prey RNF8 HIST2H2AC MI:0004(affinity chromatography technology)|MI:0415(enzymatic study) 21706008,22980979 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_194862|BIOGRID_252420 bait|bait prey|prey RNF8 PNMA2 MI:0018(two hybrid) 21516116 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_114948 bait prey RNF8 SEPT7 MI:0004(affinity chromatography technology) 23442799 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_271908 prey bait RNF8 MCPH1 MI:0416(fluorescence microscopy) 18001825 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (intact) UniProt_93673 neutral component neutral component RNF8 UBB MI:0004(affinity chromatography technology) 22266820 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_192506 bait prey RNF8 UBC MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16215985,20656690,21139048,21906983,21911360 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_172240|BIOGRID_194174|BIOGRID_193819|BIOGRID_181336|BIOGRID_154338 prey|bait|prey|prey|bait bait|prey|bait|bait|prey RNF8 UBE2V2 MI:0096(pull down) 22589545 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_188053 bait prey RNF8 CCDC85B MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(intact)|(biogrid) MINT_67946|HPRD_23663|MINT_38717|UniProt_153061|BIOGRID_80221 bait|-|bait|unspecified role|bait prey|-|prey|unspecified role|prey RNF8 JMJD1C MI:0096(pull down)|MI:0096(pull down) 24240613 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_297174|BIOGRID_297172 bait|bait prey|prey RNF8 MGMT MI:0004(affinity chromatography technology) 16226712 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_131660 prey bait RNF8 H2AFX MI:0416(fluorescence microscopy)|MI:0663(confocal microscopy)|MI:0415(enzymatic study)|MI:0416(fluorescence microscopy) 18001824,18001825,22980979 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0403(colocalization) (intact)|(intact)|(biogrid)|(intact) UniProt_93683|UniProt_92889|BIOGRID_252422|UniProt_93667 neutral component|neutral component|bait|neutral component neutral component|neutral component|prey|neutral component RNF8 RAD50 MI:0004(affinity chromatography technology) 23115235 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_248519 prey bait RNF8 PCNA MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0415(enzymatic study) 18948756,22980979 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_192586|BIOGRID_192585|BIOGRID_252423 bait|bait|bait prey|prey|prey RNF8 CEP44 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0468(hprd)|MI:0471(mint)|MI:0471(mint)|(intact) BIOGRID_79039|HPRD_23662|MINT_66442|MINT_37261|UniProt_151890 bait|-|bait|bait|unspecified role prey|-|prey|prey|unspecified role RNF8 SEPT8 MI:0004(affinity chromatography technology) 23442799 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_271910 prey bait RNF8 XRCC5 MI:0004(affinity chromatography technology) 22266820 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_192504 bait prey RNF8 MDM2 MI:0415(enzymatic study)|MI:0397(two hybrid array) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_283959|UniProt_122473 prey|bait bait|prey KDM4A RNF8 MI:0004(affinity chromatography technology) 22373579 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_185359 prey bait

PPI - HINT Gene A Gene B PMID Method Quality NBN RNF8 23115235,26869104,26869104,23115235 0004,0007,0004,0415 LC RNF8 HERC2 20023648,22508508,25305019 0004,0004,0004 LC RNF8 UBC 22266820,20656690,22266820,16215985,21911360 0415,0004,0096,0004,0004 LC RNF8 UBE2D1 22266820,11322894 0096,0096 LC RNF8 UBE2D3 18948756,23233665,22373579 0096,0096,0096 LC RNF8 UBE2N 20023648,21911360,16215985,22589545,16215985 0004,0004,0004,0096,0018 LC RNF8 MDC1 18001825,18006705,18001825,24240613,18001825,18001824,24240613,24240613,18006705,18001824,18001824,18001824,26734725,25512560 0096,0004,0065,0004,0416,0663,0006,0007,0096,0004,0007,0006,0428,0004 LC RNF8 UBE2E2 21911360,20023648,11322894,11322894 0004,0004,0096,0018 LC RNF8 WRAP53 26734725,26734725,25512560 0428,0004,0004 LC RNF8 HEL-S-71 25909880,20023648,23255131,24732096,16215985,22589545,16215985,21911360,26285145 0096,0004,0004,0004,0004,0096,0018,0004,0096 LC NBN RNF8 23115235,26869104,26869104,23115235 0004,0007,0004,0415 LC RNF8 HERC2 20023648,22508508,25305019 0004,0004,0004 LC RNF8 UBC 22266820,20656690,22266820,16215985,21911360 0415,0004,0096,0004,0004 LC RNF8 UBE2D1 22266820,11322894 0096,0096 LC RNF8 UBE2D3 18948756,23233665,22373579 0096,0096,0096 LC RNF8 UBE2N 20023648,21911360,16215985,22589545,16215985 0004,0004,0004,0096,0018 LC RNF8 MDC1 18001825,18006705,18001825,24240613,18001825,18001824,24240613,24240613,18006705,18001824,18001824,18001824,26734725,25512560 0096,0004,0065,0004,0416,0663,0006,0007,0096,0004,0007,0006,0428,0004 LC RNF8 UBE2E2 21911360,20023648,11322894,11322894 0004,0004,0096,0018 LC RNF8 WRAP53 26734725,26734725,25512560 0428,0004,0004 LC RNF8 HEL-S-71 25909880,20023648,23255131,24732096,16215985,22589545,16215985,21911360,26285145 0096,0004,0004,0004,0004,0096,0018,0004,0096 LC NR2B1 RNF8 14981089,14981089,14981089 0018,0055,0096 LC WASL RNF8 25416956,25416956,25416956,21516116,25416956 1112,0397,0018,0018,1356 HT RBFOX2 RNF8 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT NBN RNF8 18001825,23115235,23115235 0416,0004,0415 LC KDM4A RNF8 22373579 0415 LC RNF8 RNF8 22980979,22980979,22266820,11322894 0114,0826,0415,0415 LC RNF8 YEATS4 22068108 0018 LC RNF8 HERC2 22814251 0018 LC RNF8 CHEK2 22266820,22266820,22266820 0096,0415,0004 LC RNF8 RPSA 22814251,22814251,22814251 0004,0018,0428 LC RNF8 UBB 22266820 0415 LC RNF8 UBC 22266820,22266820,25909880,26285145 0415,0096,0415,0415 LC RNF8 PCNA 18948756,22980979,18948756 0415,0415,0004 LC RNF8 H2AFX 18001825,22980979,26507658 0416,0415,0415 LC RNF8 RXRA 14981089,14981089,14981089 0018,0055,0096 LC RNF8 BRCA1 18001825 0416 LC RNF8 UBE2E1 11322894,11322894 0096,0018 LC RNF8 BLM 23708797,23708797 0096,0415 LC RNF8 UBE2N 19549727,19549727,16215985,16215985 0397,0018,0004,0018 HT,LC RNF8 UBE2D2 19690564 0397 HT RNF8 MDM2 22493164,22493164 0018,0397 HT RNF8 TP53BP1 18001825 0416 LC RNF8 ATM 18001825 0416 LC RNF8 EXOSC2 15231747 0018 HT RNF8 MDC1 18001825,18001825,18001825 0096,0065,0416 LC RNF8 CCDC85B 16189514,16189514 0398,0018 HT RNF8 HIST2H2AC 21706008,22980979 0415,0415 LC RNF8 HIST2H2BE 21706008,22980979 0415,0415 LC RNF8 HOMEZ 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT RNF8 MCPH1 18001825 0416 LC RNF8 UBE2E3 11322894,11322894 0096,0018 LC RNF8 UBE2W 19549727,19549727 0397,0018 HT RNF8 UBE2E2 11322894,11322894 0096,0018 LC RNF8 TMEM79 25416956,25416956,25416956,21516116,25416956 1112,0397,0018,0018,1356 HT RNF8 CEP44 16189514,16189514 0398,0018 HT RNF8 POLD4 23233665 0415 LC RNF8 SEPT3 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT RNF8 PNMA2 25416956,25416956,25416956,21516116,25416956 1112,0397,0018,0018,1356 HT RNF8 MAD1L1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT RNF8 HEL-S-71 18678647,22814251,19549727,16215985,16215985 0018,0018,0018,0004,0018 LC,HT RNF8 HEL-S-70 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q53TS8 O76064 ALS2CR11 RNF8 0.236 unassigned1304 Q8IX15 O76064 HOMEZ RNF8 0.454 25416956 P16455 O76064 MGMT RNF8 0.126 16226712 Q9Y5T5 O76064 USP16 RNF8 0.376 25305019 Q9Y5V3 O76064 MAGED1 RNF8 0.569 27035619 O76064 O75164 RNF8 KDM4A 0.309 22373579 O95619 O76064 YEATS4 RNF8 0.523 22068108 O95999 O76064 BCL10 RNF8 0.21 24732096 P13010 O76064 XRCC5 RNF8 0.21 22266820 Q14839 O76064 CHD4 RNF8 0.659 22531782 Q15819 O76064 UBE2V2 RNF8 0.309 22589545 Q16777 O76064 HIST2H2AC RNF8 0.309 22980979 Q16778 O76064 HIST2H2BE RNF8 0.309 22980979 Q7CJX4 O76064 PROP11 RNF8 0.126 20711500 Q8NEM0 O76064 MCPH1 RNF8 0.126 18001825 Q99728 O76064 BARD1 RNF8 0.21 27035619 Q9BSE2 O76064 TMEM79 RNF8 0.659 25416956,21516116,unassigned1304 Q9BUR4 O76064 WRAP53 RNF8 0.569 25512560,26734725 Q9HCU8 O76064 POLD4 RNF8 0.309 23233665 V9HW80 O76064 HEL-S-70 {ECO:0000313|EMBL:ACI46044.1} RNF8 0.332 25416956 P01375 O76064 TNF RNF8 0.21 24980434 O95714 O76064 HERC2 RNF8 0.731 22814251,22508508,25305019,20023648 Q8IZU0 O76064 FAM9B RNF8 0.236 unassigned1304 P08393 O76064 ICP0 RNF8 0.78 20075863,22405594 Q9UL40 O76064 ZNF346 RNF8 0.236 unassigned1304 Q9UL42 O76064 PNMA2 RNF8 0.722 21516116,25416956,unassigned1304 Q9Y3C0 O76064 CCDC53 RNF8 0.236 unassigned1304 P08865 O76064 RPSA RNF8 0.623 22814251 Q96D09 O76064 GPRASP2 RNF8 0.236 unassigned1304 Q96DT7 O76064 ZBTB10 RNF8 0.236 unassigned1304 Q96IT1 O76064 ZNF496 RNF8 0.236 unassigned1304 P16104 O76064 H2AFX RNF8 0.636 18001825,22980979,26507658,18001824 Q15025 O76064 TNIP1 RNF8 0.236 unassigned1304 O76064 A1L4K1 RNF8 FSD2 0.236 unassigned1304 Q12888 O76064 TP53BP1 RNF8 0.236 18001825,20016603 Q00987 O76064 MDM2 RNF8 0.286 22493164 Q5T7B8 O76064 KIF24 RNF8 0.236 unassigned1304 Q6P2H3 O76064 CEP85 RNF8 0.236 unassigned1304 O76064 O43251 RNF8 RBFOX2 0.583 25416956,unassigned1304 P49761 O76064 CLK3 RNF8 0.236 unassigned1304 O95208 O76064 EPN2 RNF8 0.236 unassigned1304 O76064 O60934 RNF8 NBN 0.702 18001825,23115235,26869104 O76064 O75558 RNF8 STX11 0.236 unassigned1304 P60410 O76064 KRTAP10-8 RNF8 0.236 unassigned1304 Q9P1Z2 O76064 CALCOCO1 RNF8 0.236 unassigned1304 Q9NRD5 O76064 PICK1 RNF8 0.236 unassigned1304 P28482 O76064 MAPK1 RNF8 0.236 unassigned1304 O96017 O76064 CHEK2 RNF8 0.454 22266820 P50570 O76064 DNM2 RNF8 0.236 unassigned1304 P49585 O76064 PCYT1A RNF8 0.236 unassigned1304 P49760 O76064 CLK2 RNF8 0.236 unassigned1304 P51668 O76064 UBE2D1 RNF8 0.523 11322894,22266820 P54132 O76064 BLM RNF8 0.523 23708797 Q99986 O76064 VRK1 RNF8 0.376 26869104 P61968 O76064 LMO4 RNF8 0.236 unassigned1304 Q96LR5 O76064 UBE2E2 RNF8 0.765 11322894,21911360,20023648 Q15652 O76064 JMJD1C RNF8 0.454 24240613 Q9Y2J4 O76064 AMOTL2 RNF8 0.236 unassigned1304 Q9UH03 O76064 SEPT3 RNF8 0.583 25416956,unassigned1304 O76064 O00401 RNF8 WASL 0.722 21516116,25416956,unassigned1304 P12004 O76064 PCNA RNF8 0.623 22980979,18948756 P0CG48 O76064 UBC RNF8 0.671 25909880,26285145,22266820 P61077 O76064 UBE2D3 RNF8 0.671 23233665,22373579,18948756 P19793 O76064 RXRA RNF8 0.671 14981089 O76064 O76064 RNF8 RNF8 0.787 11322894,22980979,22266820,unassigned1304 Q14676 O76064 MDC1 RNF8 0.974 18001825,18006705,25512560,26734725,18001824,24240613 Q9Y6D9 O76064 MAD1L1 RNF8 0.583 25416956,unassigned1304 P61088 O76064 UBE2N RNF8 0.984 26285145,19549727,22814251,23255131,21911360,24732096,25909880,22589545,16215985,18678647,20023648 Q92878 O76064 RAD50 RNF8 0.21 23115235 Q92599 O76064 SEPT8 RNF8 0.21 23442799 Q969T4 O76064 UBE2E3 RNF8 0.523 11322894 Q96B02 O76064 UBE2W RNF8 0.286 19549727 P38398 O76064 BRCA1 RNF8 0.236 18001825 Q9C0F1 O76064 CEP44 RNF8 0.454 16189514,unassigned1304 P27661 O76064 H2AFX RNF8 0.126 18001825 P62837 O76064 UBE2D2 RNF8 0.236 19690564 Q13868 O76064 EXOSC2 RNF8 0.332 15231747 Q14134 O76064 TRIM29 RNF8 0.569 26381412 Q13315 O76064 ATM RNF8 0.126 18001825 P49959 O76064 MRE11A RNF8 0.21 23115235 P19438 O76064 TNFRSF1A RNF8 0.376 24980434 P51965 O76064 UBE2E1 RNF8 0.523 11322894 Q13416 O76064 ORC2 RNF8 0.21 18001825 Q15834 O76064 CCDC85B RNF8 0.286 16189514 Q16181 O76064 SEPT7 RNF8 0.21 23442799 P55072 O76064 VCP RNF8 0.183 25416956

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 WASL RNF8 MI:0045 experimental interaction detection MI:0461 interaction database TPP1 RNF8 MI:0362 inference MI:0461 interaction database RBFOX2 RNF8 MI:0045 experimental interaction detection MI:0461 interaction database HIST1H2BK RNF8 MI:0362 inference MI:0461 interaction database NBN RNF8 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database KDM4A RNF8 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RNF8 KDM4B MI:0362 inference MI:1106 pathways database RNF8 YEATS4 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 HERC2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RNF8 BCL10 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 CHEK2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RNF8 WHSC1 MI:0362 inference MI:1106 pathways database RNF8 TNF MI:0045 experimental interaction detection MI:0461 interaction database RNF8 HIST1H2AB MI:0362 inference MI:0461 interaction database RNF8 HIST1H2BJ MI:0362 inference MI:0461 interaction database RNF8 ERCC1 MI:0362 inference MI:0461 interaction database RNF8 RPSA MI:0045 experimental interaction detection MI:0461 interaction database RNF8 H2AFZ MI:0362 inference MI:0461 interaction database RNF8 HIST1H2AG MI:0362 inference MI:0461 interaction database RNF8 UBB MI:0362 inference MI:0461,MI:1106 interaction database,pathways database RNF8 UBC MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RNF8 PCNA MI:0045 experimental interaction detection MI:0461 interaction database RNF8 TPR MI:0362 inference MI:0461 interaction database RNF8 XRCC6 MI:0362 inference MI:1106 pathways database RNF8 XRCC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RNF8 H2AFX MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RNF8 MGMT MI:0045 experimental interaction detection MI:0461 interaction database RNF8 TNFRSF1A MI:0045 experimental interaction detection MI:0461 interaction database RNF8 RXRA MI:0045 experimental interaction detection MI:0461 interaction database RNF8 HIST1H2AD MI:0362 inference MI:0461 interaction database RNF8 HIST1H2BO MI:0362 inference MI:0461 interaction database RNF8 HIST1H2BB MI:0362 inference MI:0461 interaction database RNF8 BRCA1 MI:0362 inference MI:1106 pathways database RNF8 BRCC3 MI:0362 inference MI:1106 pathways database RNF8 MRE11A MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RNF8 UBE2D1 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 UBE2E1 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 PPP5C MI:0362 inference MI:1106 pathways database RNF8 BLM MI:0045 experimental interaction detection MI:0461 interaction database RNF8 VCP MI:0045 experimental interaction detection MI:0461 interaction database RNF8 SUMO3 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 HIST1H2BD MI:0362 inference MI:0461 interaction database RNF8 UBE2D3 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 UBE2N MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RNF8 SUMO2 MI:0362 inference MI:1106 pathways database RNF8 HIST1H4A MI:0362 inference MI:1106 pathways database RNF8 HIST1H2BC MI:0362 inference MI:0461 interaction database RNF8 UBE2D2 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 RPS27A MI:0362 inference MI:0461,MI:1106 interaction database,pathways database RNF8 UBA52 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database RNF8 SUMO1 MI:0362 inference MI:1106 pathways database RNF8 UBE2I MI:0362 inference MI:1106 pathways database RNF8 RNF4 MI:0362 inference MI:1106 pathways database RNF8 MDM2 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 TP53BP1 MI:0362 inference MI:1106 pathways database RNF8 ATM MI:0362 inference MI:1106 pathways database RNF8 UBE2V1 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 ORC2 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 EXOSC2 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 TRIM29 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 MDC1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RNF8 CHD4 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 JMJD1C MI:0045 experimental interaction detection MI:0461 interaction database RNF8 UBE2V2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RNF8 CCDC85B MI:0045 experimental interaction detection MI:0461 interaction database RNF8 NEDD8 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 SEPT7 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 HIST3H3 MI:0362 inference MI:1106 pathways database RNF8 HIST2H2AC MI:0045 experimental interaction detection MI:0461 interaction database RNF8 HIST2H2BE MI:0045 experimental interaction detection MI:0461 interaction database RNF8 UBE2NL MI:0362 inference MI:0461 interaction database RNF8 RIF1 MI:0362 inference MI:1106 pathways database RNF8 HIST2H2AA3 MI:0362 inference MI:0461 interaction database RNF8 FAM175A MI:0362 inference MI:1106 pathways database RNF8 PAXIP1 MI:0362 inference MI:1106 pathways database RNF8 HIST3H2A MI:0362 inference MI:0461 interaction database RNF8 HIST2H2AB MI:0362 inference MI:0461 interaction database RNF8 HOMEZ MI:0045 experimental interaction detection MI:0461 interaction database RNF8 RNF168 MI:0362 inference MI:1106 pathways database RNF8 HIST3H2BB MI:0362 inference MI:0461 interaction database RNF8 PIAS4 MI:0362 inference MI:1106 pathways database RNF8 SEPT8 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 RAD50 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RNF8 ERCC4 MI:0362 inference MI:0461 interaction database RNF8 KAT5 MI:0362 inference MI:1106 pathways database RNF8 HIST1H2AC MI:0362 inference MI:0461 interaction database RNF8 HIST1H2BH MI:0362 inference MI:0461 interaction database RNF8 UBE2E3 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 HIST1H2BA MI:0362 inference MI:0461 interaction database RNF8 ACD MI:0362 inference MI:0461 interaction database RNF8 UBE2W MI:0045 experimental interaction detection MI:0461 interaction database RNF8 HIST1H2AH MI:0362 inference MI:0461 interaction database RNF8 UBE2E2 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 HIST1H2AA MI:0362 inference MI:0461 interaction database RNF8 UIMC1 MI:0362 inference MI:1106 pathways database RNF8 DCLRE1C MI:0362 inference MI:1106 pathways database RNF8 BARD1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RNF8 HIST1H2BN MI:0362 inference MI:0461 interaction database RNF8 HIST1H2AJ MI:0362 inference MI:0461 interaction database RNF8 HIST1H2BM MI:0362 inference MI:0461 interaction database RNF8 HIST1H2BL MI:0362 inference MI:0461 interaction database RNF8 VRK1 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 TMEM79 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 H2AFJ MI:0362 inference MI:0461 interaction database RNF8 WRAP53 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 CEP44 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 BABAM1 MI:0362 inference MI:1106 pathways database RNF8 BRE MI:0362 inference MI:1106 pathways database RNF8 SEPT3 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 PNMA2 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 PRPF19 MI:0362 inference MI:0461 interaction database RNF8 RUVBL2 MI:0362 inference MI:0461 interaction database RNF8 USP16 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 MAGED1 MI:0045 experimental interaction detection MI:0461 interaction database RNF8 MAD1L1 MI:0045 experimental interaction detection MI:0461 interaction database