PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus IL2 BACH2 18769450 intact exp P P P P P P P P P P P P P P P P P P P BACH2 MAFF 26186194,23661758 biogrid exp G P G G GP GP G G GP G GP GP GP G GP GP GP G G P GP GP G GP GP GP P G COPS6 BACH2 21145461 biogrid exp GP P G G GP GP G GP GP G GP G GP GP G GP GP GP GP G P GP GP G GP GP GP P G BACH2 MAFB i2d exp GP P G G GP GP G G GP G GP G GP GP G G GP G GP G P GP G GP G GP GP P G ARRB1 BACH2 17620599 biogrid,intact exp GP G G GP GP G G GP G GP G GP G G GP GP G GP G P GP GP G GP GP GP P G DDIT3 BACH2 23661758 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G BACH2 NCOR2 17383980 biogrid exp GP P G G GP GP G GP GP G GP G GP G G GP GP GP GP G P GP GP G GP GP GP P G BACH2 PATZ1 10669750 hprd,biogrid exp, ortho GP P G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G BCL6 BACH2 18256039, 23023127 biogrid exp, ortho, pred G G G GP G G G G G G G G GP G G G G G G P G G G G GP G G MAFK BACH2 8887638, 25402006 hprd,i2d exp, ortho, pred G G G GP G G GP GP G G G G G G GP G G GP G P G G G GP G GP G MAFG BACH2 23661758, 25402006 biogrid,i2d exp, ortho, pred GP P G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G BACH2 BATF3 23661758, 25402006 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G FOSL2 BACH2 26186194, 25402006 biogrid exp, pred GP P G G GP GP G G GP GP G GP GP G GP GP G G G P GP GP G GP G GP G BACH2 NFE2L3 23661758, 25402006 biogrid exp, pred GP G G G P G G G G G G G G G P P G GP G G GP P G ATF7 BACH2 25402006 i2d exp, pred GP G G GP G G G G G G G G GP G G G G G G G G G G G G P G JUN BACH2 25402006 i2d exp, pred GP P G G G GP G G GP G GP G GP G G GP GP G G G P G GP G GP G GP G NFE2L1 BACH2 23661758, 25402006, 21836163 biogrid exp, pred GP P G G GP GP G GP GP G GP G GP GP G GP GP GP GP G P GP GP GP GP GP GP P G BACH2 BACH2 ortho GP P G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G BCL6B BACH2 ortho GP P G G G G G GP GP G GP G G G G GP G G G G G G G GP G GP P G ZBTB16 BACH2 23023127 ortho, pred G P G G G GP G G GP G G G GP G G GP GP G GP G GP GP G GP G G P G PLCG2 BACH2 25402006 ortho, pred G P G G GP GP G GP GP G GP G GP GP G GP GP GP G G P G G GP GP GP GP P G HMOX2 BACH2 21836163 pred GP P G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G BACH2 ACTR6 21836163 pred GP P G G GP GP G GP GP G GP GP GP GP G GP GP G GP G P GP GP GP GP G GP P G TPTE BACH2 21836163 pred PPP1CB BACH2 21836163 pred GP P G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G JDP2 BACH2 25402006 pred GP P G G GP GP G G GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G BATF BACH2 25402006 pred G G G G G G G G G G G G G G G G PRDM1 BACH2 21836163 pred GP P G G G G GP GP G G G G G G GP G G GP G P G G GP GP G GP G BTBD17 BACH2 23023127 pred P P P P P P BACH2 KLHL25 23023127 pred GP P G G G GP G P GP G GP GP GP GP G GP GP G GP G P GP GP GP GP GP GP P G CENPB BACH2 21836163 pred GP P G G G GP G GP GP G GP GP GP GP G GP GP GP GP G P GP G G GP GP GP P G BACH2 ZBTB26 23023127 pred GP P G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G ZNF131 BACH2 23023127 pred P P P P P P P P P P P P P P P P P P P P P P CBX1 BACH2 21836163 pred GP P G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G NFE2 BACH2 25402006 pred P P G GP P P P P P P P P P P P P P P P P G P P SYCP2 BACH2 21836163 pred SLX4 BACH2 23023127 pred P P G G GP GP P P G P P GP G GP GP P G P P P GP P P ZBTB5 BACH2 23023127 pred GP P G G G GP G GP GP G GP GP GP G G GP GP GP GP G P GP GP GP GP GP GP P G BACH2 ONECUT1 21836163 pred P G P GP P P P G P GP G BACH2 KLHL28 23023127 pred G G G G G G G G G GP GP G G G G G G GP G P G G G G G G G FOSB BACH2 25402006 pred GP P G G P G G GP GP GP GP GP G P GP GP G P G GP GP P GP GP P G KLHL34 BACH2 23023127 pred P P P GP GP P P P P P GP GP P P P P P GP GP P P P KLHL17 BACH2 23023127 pred P G G G G GP G P GP GP G G GP G G G GP GP G GP P G BACH2 DSN1 21836163 pred GP P G G GP P G GP GP GP GP P GP G GP P GP P P GP GP P GP GP GP P ATF2 BACH2 25402006 pred GP P G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP G GP GP GP P G JUND BACH2 25402006 pred GP P G G GP GP G G GP G GP GP GP GP G GP GP GP GP G P GP GP G GP GP GP P G USP14 BACH2 21836163 pred GP P G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G CBX5 BACH2 21836163 pred GP P G G GP GP G G GP G GP G GP GP G GP GP GP GP G P GP GP G GP GP GP P G MAF BACH2 21836163 pred GP P G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G CREB5 BACH2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G ZWINT BACH2 21836163 pred GP P G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G NSL1 BACH2 21836163 pred GP P G G GP GP G GP GP G GP G GP GP G GP GP GP GP G P GP GP GP GP GP GP P G HDAC4 BACH2 21836163 pred GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G BACH1 BACH2 25402006, 23023127 pred GP P G G GP GP G G GP G GP G GP GP G GP GP G GP G P GP GP GP GP GP GP P G BACH2 ATF5 25402006 pred GP P G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G NFE2L2 BACH2 25402006 pred GP P G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G VHL BACH2 23023127 pred G G G G G G G G G GP GP GP G G G G G P G GP GP G G G G P G ATF3 BACH2 25402006 pred GP P G G GP GP G G GP G GP GP GP G G GP GP G GP G P GP GP G GP G GP P G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P17544-6 Q9BYV9 - 12805554 - X 2 Q9BYV9 - 12805554 - X 2 A0A024R804 Q9BYV9 - 12805554 - X 2 Q9Y5Q3 Q9BYV9 - 12805554 - X 2 A0A024R8X1 Q9BYV9 - 12805554 - X 2 Q9BYV9 P05412 - 12805554 - X 2 Q9ULX9 Q9BYV9 fluorescent resonance energy transfer 23661758 direct interaction X 2 Q9ULX9 Q9BYV9 fluorescent resonance energy transfer 23661758 direct interaction X 2 Q14494 Q9BYV9 fluorescent resonance energy transfer 23661758 direct interaction X 2 P35638 Q9BYV9 fluorescent resonance energy transfer 23661758 direct interaction X 2 A0A024R1M5 Q9BYV9 two hybrid 10669750 direct interaction X 2 P0CG48 Q9BYV9 affinity chromatography technology 15060166 physical association X 2 P0CG48 Q9BYV9 pull down 19850743 direct interaction X 2 Q9BYV9 Q9Y4A8 fluorescent resonance energy transfer 23661758 direct interaction X 2 A0A024R3Z2 Q9BYV9 affinity chromatography technology 15060166 physical association X 2 A0A024R3Z2 Q9BYV9 affinity chromatography technology 15060166 physical association X 2 A0A024R8X1 Q9BYV9 fluorescent resonance energy transfer 23661758 direct interaction X 2 A0A024R8X1 Q9BYV9 fluorescent resonance energy transfer 23661758 direct interaction X 2 Q7L5N1 Q9BYV9 affinity chromatography technology 21145461 physical association X 2 Q9NR55 Q9BYV9 fluorescent resonance energy transfer 23661758 direct interaction X 2 P41182 Q9BYV9 affinity chromatography technology 18256039 physical association X 2 P41182 Q9BYV9 affinity chromatography technology 18256039 physical association X 2 P49407-2 Q9BYV9 affinity chromatography technology 17620599 physical association X 2 Q9BYV9 C9JE98 imaging technique 17383980 colocalization X 2 A0A024R804 Q9BYV9 two hybrid 8887638 - X 2 A0A024R804 Q9BYV9 in vitro 8887638 - X 2 A0A024R804 Q9BYV9 in vitro 8887638 - X 2 A0A024R804 Q9BYV9 two hybrid 8887638 - X 2 Q9HBE1-4 Q9BYV9 two hybrid 10669750 - X 2 Q9HBE1-4 Q9BYV9 in vivo 10669750 - X 2 Q9HBE1-4 Q9BYV9 in vivo 10669750 - X 2 Q9HBE1-4 Q9BYV9 two hybrid 10669750 - X 2 Q8D169 Q9BYV9 two hybrid pooling approach 20711500 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B BACH2 BATF3 MI:0055(fluorescent resonance energy transfer) 23661758 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_283355 prey bait UBC BACH2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15060166,19850743 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_208505|BIOGRID_149182 prey|bait bait|prey DDIT3 BACH2 MI:0055(fluorescent resonance energy transfer) 23661758 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_283524 bait prey BCL6 BACH2 MI:0004(affinity chromatography technology) 18256039 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_118905 prey bait SUMO1 BACH2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15060166 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_208503|BIOGRID_208504 prey|bait bait|prey BACH2 MAFF MI:0055(fluorescent resonance energy transfer)|MI:0055(fluorescent resonance energy transfer) 23661758 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_283343|BIOGRID_283303 prey|bait bait|prey ARRB1 BACH2 MI:0004(affinity chromatography technology) 17620599 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_188389 bait prey MAFG BACH2 MI:0055(fluorescent resonance energy transfer)|MI:0055(fluorescent resonance energy transfer) 23661758 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_283335|BIOGRID_283302 bait|prey prey|bait BACH2 NCOR2 MI:0428(imaging technique) 17383980 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_137244 prey bait BACH2 NFE2L3 MI:0055(fluorescent resonance energy transfer) 23661758 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_283306 prey bait COPS6 BACH2 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_205756 bait prey NFE2L1 BACH2 MI:0055(fluorescent resonance energy transfer) 23661758 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_283317 bait prey BACH2 PATZ1 MI:0018(two hybrid)|MI:0018(two hybrid) 10669750 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_116954|HPRD_13574 bait|- prey|- MAFK BACH2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 17046816,8887638 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_118645|BIOGRID_118646|HPRD_6527 bait|bait|- prey|prey|-

PPI - HINT Gene A Gene B PMID Method Quality FOSL2 BACH2 26186194 0004 HT COPS6 BACH2 21145461 0004 HT BACH2 MAFF 26186194 0004 HT FOSL2 BACH2 26186194 0004 HT COPS6 BACH2 21145461 0004 HT BACH2 MAFF 26186194 0004 HT MAFG BACH2 23661758,12805554 0055,0008 LC,HT MAFK BACH2 8887638,12805554 0018,0008 LC,HT JUN BACH2 12805554 0008 HT DDIT3 BACH2 23661758 0055 LC CREB5 BACH2 12805554 0008 HT FLJ00380 BACH2 23661758 0055 LC BACH2 PATZ1 10669750 0018 LC BACH2 BATF3 23661758 0055 LC BACH2 MAFF 23661758 0055 LC BACH2 NFE2L3 23661758 0055 LC BACH2 MAFB 12805554 0008 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9BYV9 Q8D169 BACH2 SBCC 0.126 20711500 Q9Y618 Q9BYV9 NCOR2 BACH2 0.126 17383980 Q9Y4A8 Q9BYV9 NFE2L3 BACH2 0.183 23661758 Q9BYV9 Q7L5N1 BACH2 COPS6 0.126 21145461 Q9P127 Q9BYV9 LUZP4 BACH2 0.236 unassigned1304 Q9HC52 Q9BYV9 CBX8 BACH2 0.236 unassigned1304 Q9NP66 Q9BYV9 HMG20A BACH2 0.236 unassigned1304 Q9NR55 Q9BYV9 BATF3 BACH2 0.236 unassigned1304 Q9UBR2 Q9BYV9 CTSZ BACH2 0.236 unassigned1304 Q9UBU9 Q9BYV9 NXF1 BACH2 0.236 unassigned1304 Q9UH92 Q9BYV9 MLX BACH2 0.236 unassigned1304 Q9BYV9 Q8N715 BACH2 CCDC185 0.236 unassigned1304 Q9BYV9 Q8NB12 BACH2 SMYD1 0.236 unassigned1304 Q9BYV9 Q92993 BACH2 KAT5 0.236 unassigned1304 Q9BYV9 Q8TBE0 BACH2 BAHD1 0.236 unassigned1304 Q9BYV9 Q96EZ8 BACH2 MCRS1 0.236 unassigned1304 Q9BYV9 Q14241 BACH2 TCEB3 0.236 unassigned1304 Q9BYV9 Q9BUZ4 BACH2 TRAF4 0.236 unassigned1304 Q9BYV9 Q9BUL9 BACH2 RPP25 0.236 unassigned1304 Q9BYV9 Q9BWG6 BACH2 SCNM1 0.236 unassigned1304 Q9BYV9 Q9BXS5 BACH2 AP1M1 0.236 unassigned1304 Q9NRE2 Q9BYV9 TSHZ2 BACH2 0.236 unassigned1304 Q9BYV9 A0A0C4DFQ2 BACH2 ZBTB34 {ECO:0000313|ENSEMBL:ENSP00000317534} 0.236 unassigned1304 Q9BYV9 Q15560 BACH2 TCEA2 0.236 unassigned1304 Q9BYV9 D6RBD3 BACH2 ANKRD55 {ECO:0000313|ENSEMBL:ENSP00000424230} 0.236 unassigned1304 Q9BYV9 Q15973 BACH2 ZNF124 0.236 unassigned1304 Q9BYV9 Q3B820 BACH2 FAM161A 0.236 unassigned1304 Q9BYV9 Q3KQV3 BACH2 ZNF792 0.236 unassigned1304 Q9BYV9 Q6IPU0 BACH2 CENPP 0.236 unassigned1304 Q9BYV9 Q6NT52 BACH2 CGB2 0.236 unassigned1304 Q9BYV9 Q5T655 BACH2 CCDC147 0.236 unassigned1304 Q9BYV9 Q6NX45 BACH2 ZNF774 0.236 unassigned1304 Q9BYV9 O43167 BACH2 ZBTB24 0.236 unassigned1304 Q9BYV9 Q6UWV6 BACH2 ENPP7 0.236 unassigned1304 Q9BYV9 P49407 BACH2 ARRB1 0.236 17620599 Q9BYV9 Q6ZSG2 BACH2 FAM196A 0.236 unassigned1304 Q9BYV9 P32969 BACH2 RPL9P9 0.236 unassigned1304 Q9BYV9 Q7Z4V0 BACH2 ZNF438 0.236 unassigned1304 Q9BYV9 O95363 BACH2 FARS2 0.236 unassigned1304 Q9BYV9 O60675 BACH2 MAFK 0.236 unassigned1304 Q9BYV9 O75386 BACH2 TULP3 0.236 unassigned1304 Q9BYV9 O75387 BACH2 SLC43A1 0.236 unassigned1304 Q9BYV9 Q8IWZ5 BACH2 TRIM42 0.236 unassigned1304 Q9BYV9 P62195 BACH2 PSMC5 0.236 unassigned1304 Q9BYV9 P15408 BACH2 FOSL2 0.332 unassigned1304,26186194 Q9BYV9 O15525 BACH2 MAFG 0.49 23661758,unassigned1304 Q9BYV9 P41182 BACH2 BCL6 0.376 18256039 Q9HBE1 Q9BYV9 PATZ1 BACH2 0.309 10669750 Q9ULX9 Q9BYV9 MAFF BACH2 0.416 23661758,26186194 Q9BYV9 P35638 BACH2 DDIT3 0.183 23661758 Q9BYV9 Q14494 BACH2 NFE2L1 0.183 23661758

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 MAFG BACH2 MI:0045 experimental interaction detection MI:0461 interaction database MAFK BACH2 MI:0045 experimental interaction detection MI:0461 interaction database JUN BACH2 MI:0045 experimental interaction detection MI:0461 interaction database UBC BACH2 MI:0045 experimental interaction detection MI:0461 interaction database FOSL2 BACH2 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 BACH2 MI:0362 inference MI:0461 interaction database ATF7 BACH2 MI:0045 experimental interaction detection MI:0461 interaction database DDIT3 BACH2 MI:0045 experimental interaction detection MI:0461 interaction database BCL6 BACH2 MI:0045 experimental interaction detection MI:0461 interaction database ARRB1 BACH2 MI:0045 experimental interaction detection MI:0461 interaction database NOVA1 BACH2 MI:0362 inference MI:0461 interaction database IL2 BACH2 MI:0045 experimental interaction detection MI:0461 interaction database SUMO1 BACH2 MI:0045 experimental interaction detection MI:0461 interaction database CREB5 BACH2 MI:0045 experimental interaction detection MI:0461 interaction database ZBTB16 BACH2 MI:0362 inference MI:0461 interaction database NFE2L1 BACH2 MI:0045 experimental interaction detection MI:0461 interaction database COPS6 BACH2 MI:0045 experimental interaction detection MI:0461 interaction database BCL6B BACH2 MI:0362 inference MI:0461 interaction database BACH2 PATZ1 MI:0045 experimental interaction detection MI:0461 interaction database BACH2 BATF3 MI:0045 experimental interaction detection MI:0461 interaction database BACH2 MAFF MI:0045 experimental interaction detection MI:0461 interaction database BACH2 NOVA2 MI:0362 inference MI:0461 interaction database BACH2 NFE2L3 MI:0045 experimental interaction detection MI:0461 interaction database BACH2 MAFB MI:0045 experimental interaction detection MI:0461 interaction database