PTM - CPLM Gene Name UniProt ID Type Position Code MARK1; KIAA1477; MARK Q9P0L2 Ubiquitination 783 K

PTM - dbPAF Gene Name UniProt ID Position Type Species MARK1; KIAA1477; MARK Q9P0L2 19 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 20 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 208 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 215 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 219 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 333 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 36 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 380 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 383 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 393 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 394 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 399 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 400 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 403 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 423 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 444 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 46 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 463 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 465 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 468 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 470 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 475 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 485 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 49 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 494 Y Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 498 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 5 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 504 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 505 Y Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 523 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 524 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 556 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 573 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 580 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 581 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 588 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 590 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 593 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 595 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 596 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 598 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 612 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 613 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 624 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 633 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 635 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 648 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 649 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 65 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 650 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 679 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 681 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 699 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 708 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 709 T Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 710 S Homo sapiens(Human) MARK1; KIAA1477; MARK Q9P0L2 711 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9P0L2 R646-m1 Methylation GAFAHARrGtsTGII Q9P0L2 T5-p Phosphorylation ___MSARtPLPTVNE Q9P0L2 S36-p Phosphorylation IQPTKSSsRQNIPRC Q9P0L2 S46-p Phosphorylation NIPRCRNsITSATDE Q9P0L2 T65-p Phosphorylation GNYRLQKtIGKGNFA Q9P0L2 T215-p Phosphorylation TVGNKLDtFCGsPPY Q9P0L2 S219-p Phosphorylation KLDtFCGsPPYAAPE Q9P0L2 S382-p Phosphorylation FEGGESLsSGNLCQR Q9P0L2 S393-p Phosphorylation LCQRSRPsSDLNNsT Q9P0L2 S399-p Phosphorylation PsSDLNNsTLQsPAH Q9P0L2 S403-p Phosphorylation LNNsTLQsPAHLKVQ Q9P0L2 S414-p Phosphorylation LKVQRSIsANQKQRR Q9P0L2 S423-p Phosphorylation NQKQRRFsDHAGPSI Q9P0L2 S444-p Phosphorylation TKRPQANsVESEQKE Q9P0L2 S463-p Phosphorylation DVARKLGsTTVGsKs Q9P0L2 S468-p Phosphorylation LGsTTVGsKsEMTAs Q9P0L2 S470-p Phosphorylation sTTVGsKsEMTAsPL Q9P0L2 S475-p Phosphorylation sKsEMTAsPLVGPER Q9P0L2 Y494-p Phosphorylation TIPSNNVySGGsMAR Q9P0L2 S498-p Phosphorylation NNVySGGsMARRNty Q9P0L2 T504-p Phosphorylation GsMARRNtyVCERTT Q9P0L2 Y505-p Phosphorylation sMARRNtyVCERTTD Q9P0L2 S524-p Phosphorylation LQNGKDSsLTEMSVS Q9P0L2 S554-p Phosphorylation ARPRHQKsMsTSGHP Q9P0L2 S556-p Phosphorylation PRHQKsMsTSGHPIK Q9P0L2 S573-p Phosphorylation LPTIKDGsEAYRPGt Q9P0L2 T580-p Phosphorylation sEAYRPGttQRVPAA Q9P0L2 T581-p Phosphorylation EAYRPGttQRVPAAs Q9P0L2 S588-p Phosphorylation tQRVPAAsPsAHsIs Q9P0L2 S590-p Phosphorylation RVPAAsPsAHsIstA Q9P0L2 S593-p Phosphorylation AAsPsAHsIstAtPD Q9P0L2 S595-p Phosphorylation sPsAHsIstAtPDRT Q9P0L2 T596-p Phosphorylation PsAHsIstAtPDRTR Q9P0L2 T598-p Phosphorylation AHsIstAtPDRTRFP Q9P0L2 S612-p Phosphorylation PRGSSSRstFHGEQL Q9P0L2 T613-p Phosphorylation RGSSSRstFHGEQLR Q9P0L2 S624-p Phosphorylation EQLRERRsVAYNGPP Q9P0L2 S633-p Phosphorylation AYNGPPAsPSHETGA Q9P0L2 T648-p Phosphorylation FAHARrGtsTGIISK Q9P0L2 S649-p Phosphorylation AHARrGtsTGIISKI Q9P0L2 S679-p Phosphorylation GRTDTSRsTsGEPKE Q9P0L2 S681-p Phosphorylation TDTSRsTsGEPKERD Q9P0L2 S699-p Phosphorylation GKDSKPRsLRFTWSM Q9P0L2 T708-p Phosphorylation RFTWSMKttssMDPN Q9P0L2 T709-p Phosphorylation FTWSMKttssMDPND Q9P0L2 S710-p Phosphorylation TWSMKttssMDPNDM Q9P0L2 S711-p Phosphorylation WSMKttssMDPNDMM Q9P0L2 S766-p Phosphorylation VCKLPRLsLNGVRFK Q9P0L2 S787-p Phosphorylation IAFkNIAsKIANELK Q9P0L2 K783-ub Ubiquitination SGTSIAFkNIAsKIA

PTM - dbPTM UniProt ID Position Code Type Resources References Q9P0L2 5 T Phosphorylation Swiss-Prot 1010711 18691976 Q9P0L2 46 S Phosphorylation Swiss-Prot 1010711 18691976 Q9P0L2 215 T Phosphorylation Swiss-Prot 1010711 14976552;18691976 Q9P0L2 219 S Phosphorylation Swiss-Prot 1010711 18691976 Q9P0L2 403 S Phosphorylation Swiss-Prot 1010711 18691976 Q9P0L2 423 S Phosphorylation Swiss-Prot 1010711 18691976 Q9P0L2 463 S Phosphorylation Swiss-Prot 1010711 19369195 Q9P0L2 468 S Phosphorylation Swiss-Prot 1010711 19369195 Q9P0L2 470 S Phosphorylation Swiss-Prot 1010711 19369195 Q9P0L2 475 S Phosphorylation Swiss-Prot 1010711 18691976;19369195 Q9P0L2 588 S Phosphorylation Swiss-Prot 1010711 18220336;18669648;18691976;19369195 Q9P0L2 596 T Phosphorylation Swiss-Prot 1010711 18669648 Q9P0L2 633 S Phosphorylation Swiss-Prot 1010711 18691976;19369195 Q9P0L2 649 S Phosphorylation Swiss-Prot 1010711 17192257 Q9P0L2 588 S Phosphorylation PhosphoELM.10011 18669648;18220336 Q9P0L2 590 S Phosphorylation PhosphoELM.10011 18220336 Q9P0L2 612 S Phosphorylation PhosphoELM.10011 18220336 Q9P0L2 649 S Phosphorylation PhosphoELM.10011 17192257 Q9P0L2 596 T Phosphorylation PhosphoELM.10011 18669648 Q9P0L2 598 T Phosphorylation PhosphoELM.10011 18220336 Q9P0L2 215 T Phosphorylation PhosphoELM.10011 14976552 Q9P0L2 219 S Phosphorylation Phosphositeplus.1010730 18669648;18691976;19664994 Q9P0L2 393 S Phosphorylation Phosphositeplus.1010730 20736484 Q9P0L2 399 S Phosphorylation Phosphositeplus.1010730 18691976 Q9P0L2 403 S Phosphorylation Phosphositeplus.1010730 18691976 Q9P0L2 423 S Phosphorylation Phosphositeplus.1010730 18691976 Q9P0L2 46 S Phosphorylation Phosphositeplus.1010730 18691976 Q9P0L2 463 S Phosphorylation Phosphositeplus.1010730 19369195 Q9P0L2 468 S Phosphorylation Phosphositeplus.1010730 19369195 Q9P0L2 470 S Phosphorylation Phosphositeplus.1010730 19369195 Q9P0L2 475 S Phosphorylation Phosphositeplus.1010730 18691976;19369195 Q9P0L2 588 S Phosphorylation Phosphositeplus.1010730 18220336;18669648;18691976;19276368;19369195 Q9P0L2 590 S Phosphorylation Phosphositeplus.1010730 18220336 Q9P0L2 595 S Phosphorylation Phosphositeplus.1010730 19276368 Q9P0L2 612 S Phosphorylation Phosphositeplus.1010730 18220336;19276368 Q9P0L2 633 S Phosphorylation Phosphositeplus.1010730 18691976;19369195 Q9P0L2 649 S Phosphorylation Phosphositeplus.1010730 17192257 Q9P0L2 215 T Phosphorylation Phosphositeplus.1010730 14976552;17192257;18691976;19276368;19362540;19369195;19664994;21406692;21659604 Q9P0L2 5 T Phosphorylation Phosphositeplus.1010730 18691976 Q9P0L2 504 T Phosphorylation Phosphositeplus.1010730 20736484 Q9P0L2 596 T Phosphorylation Phosphositeplus.1010730 18669648 Q9P0L2 598 T Phosphorylation Phosphositeplus.1010730 18220336 Q9P0L2 494 Y Phosphorylation Phosphositeplus.1010730 18083107 Q9P0L2 46 S Phosphorylation HPRD 9.0 18691976 Q9P0L2 219 S Phosphorylation HPRD 9.0 14976552,18691976 Q9P0L2 393 S Phosphorylation HPRD 9.0 18691976 Q9P0L2 399 S Phosphorylation HPRD 9.0 18691976 Q9P0L2 403 S Phosphorylation HPRD 9.0 18691976 Q9P0L2 423 S Phosphorylation HPRD 9.0 18691976 Q9P0L2 475 S Phosphorylation HPRD 9.0 18691976 Q9P0L2 588 S Phosphorylation HPRD 9.0 18669648,18691976 Q9P0L2 633 S Phosphorylation HPRD 9.0 18691976 Q9P0L2 5 T Phosphorylation HPRD 9.0 18691976 Q9P0L2 215 T Phosphorylation HPRD 9.0 14976552,14517247,18691976 Q9P0L2 400 T Phosphorylation HPRD 9.0 18691976 Q9P0L2 596 T Phosphorylation HPRD 9.0 18669648 Q9P0L2 648 T Phosphorylation HPRD 9.0 18691976 Q9P0L2 219 S Phosphorylation (STK11) HPRD 9.0 14976552,18691976 Q9P0L2 215 T Phosphorylation (STK11) HPRD 9.0 14976552,14517247,18691976 Q9P0L2 215 T Phosphorylation (TAOK1) HPRD 9.0 14976552,14517247,18691976 Q9P0L2 46 S Phosphorylation SysPTM 1.1 18691976 Q9P0L2 219 S Phosphorylation SysPTM 1.1 18691976 Q9P0L2 403 S Phosphorylation SysPTM 1.1 18691976 Q9P0L2 423 S Phosphorylation SysPTM 1.1 18691976 Q9P0L2 475 S Phosphorylation SysPTM 1.1 18691976 Q9P0L2 588 S Phosphorylation SysPTM 1.1 18669648;18691976 Q9P0L2 633 S Phosphorylation SysPTM 1.1 18691976 Q9P0L2 5 T Phosphorylation SysPTM 1.1 18691976 Q9P0L2 215 T Phosphorylation SysPTM 1.1 18691976 Q9P0L2 596 T Phosphorylation SysPTM 1.1 18669648

PTM - HPRD Symbol Position Code Type References MARK1 215 T Phosphorylation 14976552,14517247,18691976 MARK1 219 S Phosphorylation 14976552,18691976 MARK1 393 S Phosphorylation 18691976 MARK1 399 S Phosphorylation 18691976 MARK1 400 T Phosphorylation 18691976 MARK1 403 S Phosphorylation 18691976 MARK1 423 S Phosphorylation 18691976 MARK1 46 S Phosphorylation 18691976 MARK1 475 S Phosphorylation 18691976 MARK1 5 T Phosphorylation 18691976 MARK1 588 S Phosphorylation 18669648,18691976 MARK1 596 T Phosphorylation 18669648 MARK1 633 S Phosphorylation 18691976 MARK1 648 T Phosphorylation 18691976

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9P0L2 215 T 14976552 LKB1 LTP Phosphorylation Q9P0L2 612 S 18220336 HTP Phosphorylation Q9P0L2 598 T 18220336 HTP Phosphorylation Q9P0L2 649 S 17192257 HTP Phosphorylation Q9P0L2 596 T 18669648 HTP Phosphorylation Q9P0L2 590 S 18220336 HTP Phosphorylation Q9P0L2 588 S 18669648 HTP Phosphorylation Q9P0L2 588 S 18220336 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9P0L2 5 Phosphothreonine 18691976 Q9P0L2 208 Phosphothreonine 17573348 Q9P0L2 215 Phosphothreonine; by LKB1 and TAOK1 14976552 Q9P0L2 403 Phosphoserine 18691976 Q9P0L2 588 Phosphoserine 18669648

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type MARK1 IPI00185037 S 399 SSDLNNpSTLQSPA phosphorylation MARK1 IPI00185037 S 403 NNSTLQpSPAHLKV phosphorylation MARK1 IPI00185037 S 423 QKQRRFpSDHAGPS phosphorylation MARK1 IPI00185037 S 46 IPRCRNpSITSATD phosphorylation MARK1 IPI00185037 S 463 VARKLGpSTTVGSK phosphorylation MARK1 IPI00185037 S 468 GSTTVGpSKSEMTA phosphorylation MARK1 IPI00185037 S 470 TTVGSKpSEMTASP phosphorylation MARK1 IPI00185037 S 475 KSEMTApSPLVGPE phosphorylation MARK1 IPI00185037 S 588 QRVPAApSPSAHSI phosphorylation MARK1 IPI00185037 S 633 YNGPPApSPSHETG phosphorylation MARK1 IPI00185037 T 5 __MSARpTPLPTVN phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 4139 110309 - K Ubiquitination 21890473 4139 110309 - K Ubiquitination 23000965

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID MARK1 Homo sapiens (Human) 768 "768,GTSIAFKNIASKI" 768:21890473 MARK1 Homo sapiens (Human) 783 "783,GTSIAFKNIASKI" 783:21890473 MARK1 Homo sapiens (Human) 768 "768,GTSIAFKNIASKI" 768:21890473 MARK1 Homo sapiens (Human) 783 "783,GTSIAFKNIASKI" 783:21890473 MARK1 Homo sapiens (Human) 746 "746,GTSIAFKNIASKI" 746:21890473