PTM - CPLM Gene Name UniProt ID Type Position Code UCHL5; UCH37; AD-019; CGI-70 Q9Y5K5 Acetylation 158 K UCHL5; UCH37; AD-019; CGI-70 Q9Y5K5 Ubiquitination 154 K UCHL5; UCH37; AD-019; CGI-70 Q9Y5K5 Ubiquitination 158 K UCHL5; UCH37; AD-019; CGI-70 Q9Y5K5 Ubiquitination 234 K UCHL5; UCH37; AD-019; CGI-70 Q9Y5K5 Ubiquitination 315 K UCHL5; UCH37; AD-019; CGI-70 Q9Y5K5 Ubiquitination 126 K UCHL5; UCH37; AD-019; CGI-70 Q9Y5K5 Ubiquitination 210 K UCHL5; UCH37; AD-019; CGI-70 Q9Y5K5 Ubiquitination 277 K

PTM - dbPAF Gene Name UniProt ID Position Type Species UCHL5; UCH37; AD-019; CGI-70 Q9Y5K5 120 S Homo sapiens(Human) UCHL5; UCH37; AD-019; CGI-70 Q9Y5K5 142 S Homo sapiens(Human) UCHL5; UCH37; AD-019; CGI-70 Q9Y5K5 19 T Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9Y5K5 K158-ac Acetylation FDTkTSAkEEDAFHF Q9Y5K5 K228-ac Acetylation MAIVSDrkMIYEQkI Q9Y5K5 R227-m1 Methylation LMAIVSDrkMIYEQk Q9Y5K5 S120-p Phosphorylation EFKEFSQsFDAAMkG Q9Y5K5 S142-p Phosphorylation VIRQVHNsFARQQMF Q9Y5K5 S255-p Phosphorylation MDTDQGNsMLSAIQS Q9Y5K5 K45-ub Ubiquitination LEPENFEkLkPVHGL Q9Y5K5 K47-ub Ubiquitination PENFEkLkPVHGLIF Q9Y5K5 K57-ub Ubiquitination HGLIFLFkWQPGEEP Q9Y5K5 K126-ub Ubiquitination QsFDAAMkGLALSNS Q9Y5K5 K154-ub Ubiquitination QMFEFDTkTSAkEED Q9Y5K5 K158-ub Ubiquitination FDTkTSAkEEDAFHF Q9Y5K5 K206-ub Ubiquitination AVRPVIEkRIQkYSE Q9Y5K5 K210-ub Ubiquitination VIEkRIQkYSEGEIR Q9Y5K5 K234-ub Ubiquitination rkMIYEQkIAELQRQ Q9Y5K5 K277-ub Ubiquitination LIEEEVQkLkRYkIE Q9Y5K5 K279-ub Ubiquitination EEEVQkLkRYkIENI Q9Y5K5 K282-ub Ubiquitination VQkLkRYkIENIRRK Q9Y5K5 K301-ub Ubiquitination PFIMELLkTLAEHQQ Q9Y5K5 K315-ub Ubiquitination QLIPLVEkAkEKQNA Q9Y5K5 K317-ub Ubiquitination IPLVEkAkEKQNAKK

PTM - dbPTM UniProt ID Position Code Type Resources References Q9Y5K5 158 K Acetylation Swiss-Prot 1010711 19608861 Q9Y5K5 126 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9Y5K5 154 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9Y5K5 158 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9Y5K5 210 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9Y5K5 234 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9Y5K5 277 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9Y5K5 315 K Ubiquitylation Phosphositeplus.1010730 21906983 Q9Y5K5 158 K Acetylation Phosphositeplus.1010730 19608861 Q9Y5K5 158 K Acetylation HPRD 9.0 19608861

PTM - HPRD Symbol Position Code Type References UCHL5 158 K Acetylation 19608861

PTM - UniProt UniProt ID Position Type PMIDs Q9Y5K5 158 N6-acetyllysine 19608861

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type UCHL5 IPI00219512 K 158 DTKTSAaKEEDAFH acetylation UCHL5 IPI00219512 T 19 SDPGVFpTELIKGF phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 51377 119509 - K Ubiquitination 22118674 51377 119509 - K Ubiquitination 18781797 51377 119509 - K Ubiquitination 21987572 51377 119509 - K Ubiquitination 21963094 51377 119509 - K Ubiquitination 21139048 51377 119509 - K Ubiquitination 21890473 51377 119509 - K Ubiquitination 21906983 51377 119509 - K Sumoylation 19471022 51377 119509 - K Ubiquitination 22505724 51377 119509 - K Ubiquitination 22053931 51377 119509 - K Ubiquitination 24654937 51377 119509 - K Ubiquitination 24816145 51377 119509 - K Ubiquitination 24811749 51377 119509 - K Ubiquitination 25147182 51377 119509 - K Ubiquitination 24743594

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID UCHL5 Homo sapiens (Human) 154; 234; 158; 276; 126; 314; 210 "154,MFEFDTKTSAKEE; 234,KMIYEQKIAELQR; 158,DTKTSAKEEDAFH; 276,IEEEVQKLKRYKI; 126,SFDAAMKGLALSN; 314,LIPLVEKAKEKQN; 210,IEKRIQKYSEGEI" "154:21890473,21906983; 234:21890473,21906983; 158:21890473,21906983; 276:21906983; 126:21906983; 314:21890473,21906983; 210:21906983" UCHL5 Homo sapiens (Human) 154; 234; 158; 276; 126; 210 "154,MFEFDTKTSAKEE; 234,KMIYEQKIAELQR; 158,DTKTSAKEEDAFH; 276,IEEEVQKLKRYKI; 126,SFDAAMKGLALSN; 210,IEKRIQKYSEGEI" "154:21890473,21906983; 234:21890473,21906983; 158:21890473,21906983; 276:21906983; 126:21906983; 210:21906983" UCHL5 Homo sapiens (Human) 154; 234; 158; 277; 126; 315; 210 "154,MFEFDTKTSAKEE; 234,KMIYEQKIAELQR; 158,DTKTSAKEEDAFH; 277,IEEEVQKLKRYKI; 126,SFDAAMKGLALSN; 315,LIPLVEKAKEKQN; 210,IEKRIQKYSEGEI" "154:21890473,21906983; 234:21890473,21906983; 158:21890473,21906983; 277:21906983; 126:21906983; 315:21890473,21906983; 210:21906983" UCHL5 Homo sapiens (Human) 154; 234; 158; 276; 126; 210 "154,MFEFDTKTSAKEE; 234,KMIYEQKIAELQR; 158,DTKTSAKEEDAFH; 276,IEEEVQKLKRYKI; 126,SFDAAMKGLALSN; 210,IEKRIQKYSEGEI" "154:21890473,21906983; 234:21890473,21906983; 158:21890473,21906983; 276:21906983; 126:21906983; 210:21906983" UCHL5 Homo sapiens (Human) 154; 234; 158; 314 "154,MFEFDTKTSAKEE; 234,KMIYEQKIAELQR; 158,DTKTSAKEEDAFH; 314,LIPLVEKAKEKQN" 154:21890473; 234:21890473; 158:21890473; 314:21890473 UCHL5 Homo sapiens (Human) 144; 148; 224 "144,MFEFDTKTSAKEE; 148,DTKTSAKEEDAFH; 224,KMIYEQKIAELQR" 144:21890473; 148:21890473; 224:21890473 UCHL5 Homo sapiens (Human) 154; 234; 158 "154,MFEFDTKTSAKEE; 234,KMIYEQKIAELQR; 158,DTKTSAKEEDAFH" 154:21890473; 234:21890473; 158:21890473 UCHL5 Homo sapiens (Human) 154; 234; 158; 315 "154,MFEFDTKTSAKEE; 234,KMIYEQKIAELQR; 158,DTKTSAKEEDAFH; 315,LIPLVEKAKEKQN" 154:21890473; 234:21890473; 158:21890473; 315:21890473 UCHL5 Homo sapiens (Human) 154; 341; 158; 261; 126; 303 "154,MFEFDTKTSAKEE; 341,LIPLVEKAKEKQN; 158,DTKTSAKEEDAFH; 261,KMIYEQKIAELQR; 126,SFDAAMKGLALSN; 303,IEEEVQKLKRYKI" "154:21906983,21890473; 341:21906983,21890473; 158:21906983,21890473; 261:21906983,21890473; 126:21906983; 303:21906983" UCHL5 Homo sapiens (Human) 144; 148; 224 "144,MFEFDTKTSAKEE; 148,DTKTSAKEEDAFH; 224,KMIYEQKIAELQR" 144:21890473; 148:21890473; 224:21890473 UCHL5 Homo sapiens (Human) 170; 273; 138; 354; 166; 316 "170,DTKTSAKEEDAFH; 273,KMIYEQKIAELQR; 138,SFDAAMKGLALSN; 354,LIPLVEKAKEKQN; 166,MFEFDTKTSAKEE; 316,IEEEVQKLKRYKI" "170:21906983,21890473; 273:21906983,21890473; 138:21906983; 354:21906983,21890473; 166:21906983,21890473; 316:21906983" UCHL5 Homo sapiens (Human) 117; 201; 145; 149; 225 "117,SFDAAMKGLALSN; 201,IEKRIQKYSEGEI; 145,MFEFDTKTSAKEE; 149,DTKTSAKEEDAFH; 225,KMIYEQKIAELQR" "117:21906983; 201:21906983; 145:21906983,21890473; 149:21906983,21890473; 225:21906983,21890473" UCHL5 Homo sapiens (Human) 17 "17,KMIYEQKIAELQR" 17:21890473 UCHL5 Homo sapiens (Human) 10; 14; 90 "10,MFEFDTKTSAKEE; 14,DTKTSAKEEDAFH; 90,KMIYEQKIAELQR" 10:21890473; 14:21890473; 90:21890473 UCHL5 Homo sapiens (Human) 23 "23,KMIYEQKIAELQR" 23:21890473 UCHL5 Homo sapiens (Human) 17 "17,KMIYEQKIAELQR" 153:21906983; 110:21906983 UCHL5 Homo sapiens (Human) 66; 133; 14; 90 "66,IEKRIQKYSEGEI; 133,IEEEVQKLKRYKI; 14,DTKTSAKEEDAFH; 90,KMIYEQKIAELQR" 66:21906983; 133:21906983; 14:21906983; 90:21906983 UCHL5 Homo sapiens (Human) 23 "23,KMIYEQKIAELQR" 152:21906983; 110:21906983