PTM - CPLM Gene Name UniProt ID Type Position Code IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 Acetylation 458 K IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 Ubiquitination 79 K

PTM - dbPAF Gene Name UniProt ID Position Type Species IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 13 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 135 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 2 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 203 T Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 215 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 218 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 219 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 224 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 227 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 313 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 334 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 336 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 337 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 338 T Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 388 Y Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 397 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 519 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 540 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 547 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 553 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 610 T Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 611 T Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 622 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 633 T Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 636 T Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 639 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 657 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 658 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 659 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 662 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 665 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 69 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 7 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 705 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 8 S Homo sapiens(Human) IRF2BPL; C14orf4; EAP1; KIAA1865; My039 Q9H1B7 9 S Homo sapiens(Human)

PTM - PhosSNP Gene Name dbSNP ID Gene Mutation AA Mutation Mutation Position Code Peptide Score Modification Type IRF2BPL; C14orf4; EAP1; KIAA1865; My039 rs28692724 AGC->AAC S->N 658 S ASARRNSSSPVSPAS 658 Phosphorylation TypeI- IRF2BPL; C14orf4; EAP1; KIAA1865; My039 rs61991638 AGC->AAC S->N 658 S ASARRNSSSPVSPAS 658 Phosphorylation TypeI- IRF2BPL; C14orf4; EAP1; KIAA1865; My039 rs12886014 CCG->TCG P->S 547 S SLRKRKASPEPPDSA 547 Phosphorylation TypeIII- IRF2BPL; C14orf4; EAP1; KIAA1865; My039 rs12886014 CCG->TCG P->S 553 S ASPEPPDSAEGALKL 553 Phosphorylation TypeIII- IRF2BPL; C14orf4; EAP1; KIAA1865; My039 rs28692724 AGC->AAC S->N 657 S TASARRNSSSPVSPA 657 Phosphorylation TypeIII- IRF2BPL; C14orf4; EAP1; KIAA1865; My039 rs28692724 AGC->AAC S->N 659 S SARRNSSSPVSPASV 659 Phosphorylation TypeIII- IRF2BPL; C14orf4; EAP1; KIAA1865; My039 rs28692724 AGC->AAC S->N 662 S RNSSSPVSPASVPGQ 662 Phosphorylation TypeIII- IRF2BPL; C14orf4; EAP1; KIAA1865; My039 rs61991638 AGC->AAC S->N 657 S TASARRNSSSPVSPA 657 Phosphorylation TypeIII- IRF2BPL; C14orf4; EAP1; KIAA1865; My039 rs61991638 AGC->AAC S->N 659 S SARRNSSSPVSPASV 659 Phosphorylation TypeIII- IRF2BPL; C14orf4; EAP1; KIAA1865; My039 rs61991638 AGC->AAC S->N 662 S RNSSSPVSPASVPGQ 662 Phosphorylation TypeIII-

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9H1B7 K458-ac Acetylation RGLSSGFkYLEYEKK Q9H1B7 R170-m1 Methylation AAVEQRSrFEYPPPP Q9H1B7 S2-p Phosphorylation ______MsAAQVsss Q9H1B7 S7-p Phosphorylation _MsAAQVsssRRQsC Q9H1B7 S8-p Phosphorylation MsAAQVsssRRQsCY Q9H1B7 S9-p Phosphorylation sAAQVsssRRQsCYL Q9H1B7 S13-p Phosphorylation VsssRRQsCYLCDLP Q9H1B7 S69-p Phosphorylation GCFQDGRsPGPPPPV Q9H1B7 S135-p Phosphorylation LNHVdGSsKPAVLAA Q9H1B7 S152-p Phosphorylation GLERYGLsAAAAAAA Q9H1B7 S215-p Phosphorylation PPELNRQsPNssSAA Q9H1B7 S218-p Phosphorylation LNRQsPNssSAAAsV Q9H1B7 S219-p Phosphorylation NRQsPNssSAAAsVA Q9H1B7 S224-p Phosphorylation NssSAAAsVAsRRGT Q9H1B7 S227-p Phosphorylation SAAAsVAsRRGTHGG Q9H1B7 T286-p Phosphorylation LGSRGPPtPAPPGAP Q9H1B7 S334-p Phosphorylation AGGKRPGsVsstDQE Q9H1B7 S336-p Phosphorylation GKRPGsVsstDQERE Q9H1B7 S337-p Phosphorylation KRPGsVsstDQEREL Q9H1B7 T338-p Phosphorylation RPGsVsstDQERELK Q9H1B7 Y388-p Phosphorylation TLAGCTPyEVRFKKD Q9H1B7 S397-p Phosphorylation VRFKKDHsLLGRVFA Q9H1B7 S519-p Phosphorylation VSLSRAPsAPPGtGA Q9H1B7 T524-p Phosphorylation APsAPPGtGALPPAA Q9H1B7 S540-p Phosphorylation SGRGAAAsLRKRKAs Q9H1B7 S547-p Phosphorylation sLRKRKAsPEPPDsA Q9H1B7 S553-p Phosphorylation AsPEPPDsAEGALKL Q9H1B7 T610-p Phosphorylation LGPHSNRttPPESAP Q9H1B7 T611-p Phosphorylation GPHSNRttPPESAPQ Q9H1B7 S622-p Phosphorylation SAPQNGPsPMAALMS Q9H1B7 S639-p Phosphorylation DTLGTAHsPKDGSSV Q9H1B7 S657-p Phosphorylation TASARRNsssPVsPA Q9H1B7 S658-p Phosphorylation ASARRNsssPVsPAs Q9H1B7 S659-p Phosphorylation SARRNsssPVsPAsV Q9H1B7 S662-p Phosphorylation RNsssPVsPAsVPGQ Q9H1B7 S665-p Phosphorylation ssPVsPAsVPGQRRL Q9H1B7 S705-p Phosphorylation HPQNIPDsPMANSGP Q9H1B7 K458-sm Sumoylation RGLSSGFkYLEYEKK Q9H1B7 K79-ub Ubiquitination PPPPVGVkTVALSAK Q9H1B7 K373-ub Ubiquitination EEWASKPkMVRDTLL Q9H1B7 K748-ub Ubiquitination PCSRESIkAQGATGE

PTM - dbPTM UniProt ID Position Code Type Resources References Q9H1B7 69 S Phosphorylation Swiss-Prot 1010711 18669648;19690332 Q9H1B7 547 S Phosphorylation Swiss-Prot 1010711 17081983;17287340;18187866;18669648;19413330;19690332 Q9H1B7 657 S Phosphorylation Swiss-Prot 1010711 15302935;18220336;18669648;19690332 Q9H1B7 658 S Phosphorylation Swiss-Prot 1010711 18220336;18669648 Q9H1B7 659 S Phosphorylation Swiss-Prot 1010711 15302935;18187866;18220336;18669648;19413330;19690332 Q9H1B7 662 S Phosphorylation Swiss-Prot 1010711 15302935;18220336;18669648;19413330;19690332 Q9H1B7 665 S Phosphorylation Swiss-Prot 1010711 19413330 Q9H1B7 69 S Phosphorylation PhosphoELM.10011 18669648 Q9H1B7 215 S Phosphorylation PhosphoELM.10011 18669648 Q9H1B7 224 S Phosphorylation PhosphoELM.10011 18669648 Q9H1B7 313 S Phosphorylation PhosphoELM.10011 15302935 Q9H1B7 334 S Phosphorylation PhosphoELM.10011 15302935 Q9H1B7 547 S Phosphorylation PhosphoELM.10011 18669648;17081983 Q9H1B7 553 S Phosphorylation PhosphoELM.10011 17081983 Q9H1B7 657 S Phosphorylation PhosphoELM.10011 18669648;18220336;17081983;15302935 Q9H1B7 658 S Phosphorylation PhosphoELM.10011 18669648;18220336 Q9H1B7 659 S Phosphorylation PhosphoELM.10011 18669648;18220336;17081983;15302935 Q9H1B7 662 S Phosphorylation PhosphoELM.10011 18669648;18220336;17081983;15302935 Q9H1B7 665 S Phosphorylation PhosphoELM.10011 18669648 Q9H1B7 338 T Phosphorylation PhosphoELM.10011 15302935 Q9H1B7 132 D Caspase Phosphositeplus.1010730 18722006 Q9H1B7 2 S Phosphorylation Phosphositeplus.1010730 21406692 Q9H1B7 215 S Phosphorylation Phosphositeplus.1010730 18669648;19362540 Q9H1B7 224 S Phosphorylation Phosphositeplus.1010730 20044836 Q9H1B7 227 S Phosphorylation Phosphositeplus.1010730 20044836 Q9H1B7 334 S Phosphorylation Phosphositeplus.1010730 15302935;18707149;20363803 Q9H1B7 337 S Phosphorylation Phosphositeplus.1010730 20363803 Q9H1B7 540 S Phosphorylation Phosphositeplus.1010730 21406692 Q9H1B7 547 S Phosphorylation Phosphositeplus.1010730 17287340;18187866;18669648;18707149;19276368;19362540;19664995;19690332;20044836;20068231;20166139;20363803;20815410;21406692 Q9H1B7 553 S Phosphorylation Phosphositeplus.1010730 19276368;19362540 Q9H1B7 639 S Phosphorylation Phosphositeplus.1010730 19690332;22115753 Q9H1B7 657 S Phosphorylation Phosphositeplus.1010730 15302935;16964243;18220336;18669648;19276368;19415658;19690332;20044836;20166139;20736484;21659604;22115753 Q9H1B7 658 S Phosphorylation Phosphositeplus.1010730 16964243;18220336;18669648;19664995;19690332;20068231;20166139;20736484;21406692 Q9H1B7 659 S Phosphorylation Phosphositeplus.1010730 15302935;16964243;18187866;18220336;18669648;19276368;19362540;19415658;19664994;19664995;19690332;20044836;20068231;20164059;20166139;20736484;21406692;22115753 Q9H1B7 662 S Phosphorylation Phosphositeplus.1010730 15302935;16964243;18220336;18669648;19276368;19664995;19690332;20164059;20363803;20736484;21406692;22115753 Q9H1B7 665 S Phosphorylation Phosphositeplus.1010730 22115753 Q9H1B7 69 S Phosphorylation Phosphositeplus.1010730 18669648;19690332;20363803;21406692 Q9H1B7 7 S Phosphorylation Phosphositeplus.1010730 21406692 Q9H1B7 8 S Phosphorylation Phosphositeplus.1010730 21406692 Q9H1B7 9 S Phosphorylation Phosphositeplus.1010730 21406692 Q9H1B7 338 T Phosphorylation Phosphositeplus.1010730 15302935 Q9H1B7 69 S Phosphorylation HPRD 9.0 18669648 Q9H1B7 215 S Phosphorylation HPRD 9.0 18669648,20068231 Q9H1B7 224 S Phosphorylation HPRD 9.0 18669648 Q9H1B7 334 S Phosphorylation HPRD 9.0 19651622 Q9H1B7 547 S Phosphorylation HPRD 9.0 17322306,18669648,19413330,17287340,19664995,18212344,19651622,18707149,18452278,18767875,20166139,20068231 Q9H1B7 553 S Phosphorylation HPRD 9.0 17081983,20068231 Q9H1B7 639 S Phosphorylation HPRD 9.0 18452278 Q9H1B7 657 S Phosphorylation HPRD 9.0 15302935,18669648,19415658,19651622,18452278,20166139,20068231 Q9H1B7 658 S Phosphorylation HPRD 9.0 17081983,18669648,19664995,19651622,18452278,20166139,20068231 Q9H1B7 659 S Phosphorylation HPRD 9.0 15345747,15302935,18669648,19413330,19415658,19664995,19651622,19664994,18452278,20166139,20068231 Q9H1B7 662 S Phosphorylation HPRD 9.0 15302935,18669648,19413330,19664995,19651622,16964243,18452278 Q9H1B7 665 S Phosphorylation HPRD 9.0 17081983,18669648,19413330,19651622 Q9H1B7 338 T Phosphorylation HPRD 9.0 19651622 Q9H1B7 610 T Phosphorylation HPRD 9.0 18452278 Q9H1B7 611 T Phosphorylation HPRD 9.0 18452278 Q9H1B7 69 S Phosphorylation SysPTM 1.1 18669648 Q9H1B7 334 S Phosphorylation SysPTM 1.1 18707149 Q9H1B7 547 S Phosphorylation SysPTM 1.1 18707149;17081983;18669648;18212344 Q9H1B7 553 S Phosphorylation SysPTM 1.1 17081983 Q9H1B7 657 S Phosphorylation SysPTM 1.1 15302935;17081983;16964243;18669648 Q9H1B7 658 S Phosphorylation SysPTM 1.1 17081983;16964243;18669648 Q9H1B7 659 S Phosphorylation SysPTM 1.1 15302935;17081983;16964243;18669648 Q9H1B7 662 S Phosphorylation SysPTM 1.1 15302935;17081983;16964243;18669648 Q9H1B7 665 S Phosphorylation SysPTM 1.1 17081983

PTM - HPRD Symbol Position Code Type References C14orf4 215 S Phosphorylation 18669648,20068231 C14orf4 224 S Phosphorylation 18669648 C14orf4 334 S Phosphorylation 19651622 C14orf4 338 T Phosphorylation 19651622 C14orf4 547 S Phosphorylation 17322306,18669648,19413330,17287340,19664995,18212344,19651622,18707149,18452278,18767875,20166139,20068231 C14orf4 553 S Phosphorylation 17081983,20068231 C14orf4 610 T Phosphorylation 18452278 C14orf4 611 T Phosphorylation 18452278 C14orf4 639 S Phosphorylation 18452278 C14orf4 657 S Phosphorylation 15302935,18669648,19415658,19651622,18452278,20166139,20068231 C14orf4 658 S Phosphorylation 17081983,18669648,19664995,19651622,18452278,20166139,20068231 C14orf4 659 S Phosphorylation 15345747,15302935,18669648,19413330,19415658,19664995,19651622,19664994,18452278,20166139,20068231 C14orf4 662 S Phosphorylation 15302935,18669648,19413330,19664995,19651622,16964243,18452278 C14orf4 665 S Phosphorylation 17081983,18669648,19413330,19651622 C14orf4 69 S Phosphorylation 18669648

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9H1B7 215 S 18669648 HTP Phosphorylation Q9H1B7 338 T 15302935 HTP Phosphorylation Q9H1B7 662 S 18669648 HTP Phosphorylation Q9H1B7 662 S 18220336 HTP Phosphorylation Q9H1B7 662 S 17081983 HTP Phosphorylation Q9H1B7 662 S 15302935 HTP Phosphorylation Q9H1B7 659 S 18669648 HTP Phosphorylation Q9H1B7 659 S 18220336 HTP Phosphorylation Q9H1B7 659 S 17081983 HTP Phosphorylation Q9H1B7 659 S 15302935 HTP Phosphorylation Q9H1B7 547 S 18669648 HTP Phosphorylation Q9H1B7 547 S 17081983 HTP Phosphorylation Q9H1B7 224 S 18669648 HTP Phosphorylation Q9H1B7 658 S 18669648 HTP Phosphorylation Q9H1B7 658 S 18220336 HTP Phosphorylation Q9H1B7 69 S 18669648 HTP Phosphorylation Q9H1B7 657 S 18669648 HTP Phosphorylation Q9H1B7 657 S 18220336 HTP Phosphorylation Q9H1B7 657 S 17081983 HTP Phosphorylation Q9H1B7 657 S 15302935 HTP Phosphorylation Q9H1B7 334 S 15302935 HTP Phosphorylation Q9H1B7 553 S 17081983 HTP Phosphorylation Q9H1B7 665 S 18669648 HTP Phosphorylation Q9H1B7 313 S 15302935 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9H1B7 69 Phosphoserine 23186163 Q9H1B7 215 Phosphoserine 24275569 Q9H1B7 519 Phosphoserine 23186163;24275569 Q9H1B7 547 Phosphoserine 18669648;19690332;21406692;23186163;24275569 Q9H1B7 639 Phosphoserine 23186163 Q9H1B7 657 Phosphoserine 18669648;19690332;23186163;24275569 Q9H1B7 658 Phosphoserine 18669648 Q9H1B7 659 Phosphoserine 18669648;19690332;21406692;23186163;24275569 Q9H1B7 662 Phosphoserine 16964243;18220336;18669648;19690332;21406692;23186163;24275569

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 64207 122101 - K Sumoylation 21693764 64207 122101 - K Ubiquitination 21139048 64207 122101 - K Sumoylation 19471022 64207 122101 - K Sumoylation 21252943 64207 122101 - K Ubiquitination 23000965