Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 6 150048189 150048189 + Silent SNP C C T TCGA-G2-A2EF-01A-12D-A18F-08 TCGA-G2-A2EF-10A-01D-A18F-08 g.chr6:150048189C>T c.1059G>A c.(1057-1059)gtG>gtA p.V353V BLCA 6 150057633 150057633 + Missense_Mutation SNP G G C TCGA-ZF-A9R7-01A-11D-A38G-08 TCGA-ZF-A9R7-10A-01D-A38J-08 g.chr6:150057633G>C c.764C>G c.(763-765)tCt>tGt p.S255C BLCA 6 150057650 150057650 + Silent SNP T T C TCGA-DK-AA6X-01A-12D-A42E-08 TCGA-DK-AA6X-10A-01D-A42H-08 g.chr6:150057650T>C c.747A>G c.(745-747)caA>caG p.Q249Q BLCA 6 150059906 150059906 + Missense_Mutation SNP C C G TCGA-FD-A3SO-01A-11D-A22Z-08 TCGA-FD-A3SO-10A-01D-A22Z-08 g.chr6:150059906C>G c.511G>C c.(511-513)Gat>Cat p.D171H BLCA 6 150063558 150063558 + Missense_Mutation SNP C C G TCGA-XF-A9T5-01A-11D-A42E-08 TCGA-XF-A9T5-10A-01D-A42H-08 g.chr6:150063558C>G c.470G>C c.(469-471)aGa>aCa p.R157T BLCA 6 150067104 150067104 + Missense_Mutation SNP C C G TCGA-CF-A1HS-01A-11D-A13W-08 TCGA-CF-A1HS-10A-01D-A13W-08 g.chr6:150067104C>G c.215G>C c.(214-216)aGa>aCa p.R72T BLCA 6 150067551 150067551 + Missense_Mutation SNP C C G TCGA-4Z-AA7M-01A-11D-A391-08 TCGA-4Z-AA7M-10A-01D-A394-08 g.chr6:150067551C>G c.81G>C c.(79-81)caG>caC p.Q27H BRCA 6 150052790 150052790 + Missense_Mutation SNP G G A TCGA-D8-A1J8-01A-11D-A13L-09 TCGA-D8-A1J8-10A-01D-A13O-09 g.chr6:150052790G>A c.872C>T c.(871-873)gCt>gTt p.A291V BRCA 6 150059887 150059887 + Missense_Mutation SNP G G C TCGA-A7-A5ZV-01A-11D-A28B-09 TCGA-A7-A5ZV-10A-01D-A28E-09 g.chr6:150059887G>C c.530C>G c.(529-531)gCt>gGt p.A177G BRCA 6 150067514 150067514 + Nonsense_Mutation SNP C C A TCGA-AC-A23H-01A-11D-A159-09 TCGA-AC-A23H-11A-12D-A17G-09 g.chr6:150067514C>A c.118G>T c.(118-120)Gag>Tag p.E40* COAD 6 150048312 150048313 + Frame_Shift_Ins INS - - A TCGA-G4-6588-01A-11D-1771-10 TCGA-G4-6588-10A-01D-1771-10 g.chr6:150048312_150048313insA c.935_936insT c.(934-936)ttgfs p.L312fs COAD 6 150063595 150063595 + Missense_Mutation SNP C C T TCGA-AA-3516-01A-02W-0833-10 TCGA-AA-3516-10A-01W-0833-10 g.chr6:150063595C>T c.433G>A c.(433-435)Gtt>Att p.V145I COAD 6 150063668 150063668 + Nonsense_Mutation SNP G G T TCGA-AD-6964-01A-11D-1924-10 TCGA-AD-6964-10A-01D-1924-10 g.chr6:150063668G>T c.360C>A c.(358-360)taC>taA p.Y120* COAD 6 150067178 150067179 + Missense_Mutation DNP CC CC AA TCGA-AA-3941-01A-01W-0995-10 TCGA-AA-3941-10A-01W-0995-10 g.chr6:150067178_150067179CC>AA c.140_141GG>TT c.(139-141)tGG>tTT p.W47F COADREAD 6 150048312 150048313 + Frame_Shift_Ins INS - - A TCGA-G4-6588-01A-11D-1771-10 TCGA-G4-6588-10A-01D-1771-10 g.chr6:150048312_150048313insA c.935_936insT c.(934-936)ttgfs p.L312fs COADREAD 6 150063595 150063595 + Missense_Mutation SNP C C T TCGA-AA-3516-01A-02W-0833-10 TCGA-AA-3516-10A-01W-0833-10 g.chr6:150063595C>T c.433G>A c.(433-435)Gtt>Att p.V145I COADREAD 6 150063650 150063650 + Missense_Mutation SNP A A T TCGA-AH-6544-01A-11D-1826-10 TCGA-AH-6544-10A-01D-1826-10 g.chr6:150063650A>T c.378T>A c.(376-378)agT>agA p.S126R COADREAD 6 150063668 150063668 + Nonsense_Mutation SNP G G T TCGA-AD-6964-01A-11D-1924-10 TCGA-AD-6964-10A-01D-1924-10 g.chr6:150063668G>T c.360C>A c.(358-360)taC>taA p.Y120* COADREAD 6 150067178 150067179 + Missense_Mutation DNP CC CC AA TCGA-AA-3941-01A-01W-0995-10 TCGA-AA-3941-10A-01W-0995-10 g.chr6:150067178_150067179CC>AA c.140_141GG>TT c.(139-141)tGG>tTT p.W47F ESCA 6 150052823 150052823 + Missense_Mutation SNP C C T TCGA-L5-A891-01A-11D-A36J-09 TCGA-L5-A891-11A-21D-A36M-09 g.chr6:150052823C>T c.839G>A c.(838-840)tGc>tAc p.C280Y GBMLGG 6 150059820 150059820 + Missense_Mutation SNP A A C TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr6:150059820A>C c.597T>G c.(595-597)gaT>gaG p.D199E HNSC 6 150052833 150052833 + Missense_Mutation SNP G G C TCGA-CR-6472-01A-11D-1870-08 TCGA-CR-6472-10A-01D-1870-08 g.chr6:150052833G>C c.829C>G c.(829-831)Ctt>Gtt p.L277V HNSC 6 150063646 150063646 + Missense_Mutation SNP A A G TCGA-F7-A624-01A-22D-A30E-08 TCGA-F7-A624-10A-01D-A30H-08 g.chr6:150063646A>G c.382T>C c.(382-384)Tcc>Ccc p.S128P KIPAN 6 150059828 150059828 + Frame_Shift_Del DEL T T - TCGA-SX-A71U-01A-12D-A33Q-10 TCGA-SX-A71U-10A-01D-A33Q-10 g.chr6:150059828delT c.589delA c.(589-591)atafs p.I197fs KIRP 6 150059828 150059828 + Frame_Shift_Del DEL T T - TCGA-SX-A71U-01A-12D-A33Q-10 TCGA-SX-A71U-10A-01D-A33Q-10 g.chr6:150059828delT c.589delA c.(589-591)atafs p.I197fs LGG 6 150059820 150059820 + Missense_Mutation SNP A A C TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr6:150059820A>C c.597T>G c.(595-597)gaT>gaG p.D199E LIHC 6 150059861 150059861 + Missense_Mutation SNP T T C TCGA-DD-A3A1-01A-11D-A20W-10 TCGA-DD-A3A1-11A-11D-A20W-10 g.chr6:150059861T>C c.556A>G c.(556-558)Att>Gtt p.I186V LIHC 6 150067096 150067096 + Missense_Mutation SNP C C T TCGA-ES-A2HS-01A-11D-A183-10 TCGA-ES-A2HS-11A-11D-A183-10 g.chr6:150067096C>T c.223G>A c.(223-225)Ggt>Agt p.G75S LUAD 6 150048227 150048227 + Missense_Mutation SNP C C G TCGA-78-7539-01A-11D-2063-08 TCGA-78-7539-10A-01D-2063-08 g.chr6:150048227C>G c.1021G>C c.(1021-1023)Gaa>Caa p.E341Q LUAD 6 150057671 150057671 + Missense_Mutation SNP C C A TCGA-05-4433-01A-22D-1855-08 TCGA-05-4433-10A-01D-1855-08 g.chr6:150057671C>A c.726G>T c.(724-726)ttG>ttT p.L242F LUAD 6 150057682 150057682 + Missense_Mutation SNP C C G TCGA-55-7907-01A-11D-2167-08 TCGA-55-7907-10A-01D-2167-08 g.chr6:150057682C>G c.715G>C c.(715-717)Gat>Cat p.D239H LUAD 6 150064774 150064774 + Splice_Site SNP C C G TCGA-17-Z031-01A-01W-0746-08 TCGA-17-Z031-11A-01W-0746-08 g.chr6:150064774C>G c.321G>C c.(319-321)caG>caC p.Q107H LUAD 6 150064778 150064778 + Missense_Mutation SNP T T A TCGA-05-4389-01A-01D-1265-08 TCGA-05-4389-10A-01D-1265-08 g.chr6:150064778T>A c.317A>T c.(316-318)aAc>aTc p.N106I LUAD 6 150064827 150064827 + Missense_Mutation SNP C C T TCGA-73-7499-01A-11D-2184-08 TCGA-73-7499-10A-01D-2184-08 g.chr6:150064827C>T c.268G>A c.(268-270)Gct>Act p.A90T LUAD 6 150067624 150067624 + Missense_Mutation SNP T T C TCGA-55-8506-01A-11D-2393-08 TCGA-55-8506-10A-01D-2393-08 g.chr6:150067624T>C c.8A>G c.(7-9)gAa>gGa p.E3G LUSC 6 150067096 150067096 + Missense_Mutation SNP C C A TCGA-18-3410-01A-01D-0983-08 TCGA-18-3410-11A-01D-0983-08 g.chr6:150067096C>A c.223G>T c.(223-225)Ggt>Tgt p.G75C PRAD 6 150048281 150048281 + Missense_Mutation SNP G G A TCGA-EJ-5519-01A-01D-1576-08 TCGA-EJ-5519-10A-01D-1577-08 g.chr6:150048281G>A c.967C>T c.(967-969)Cac>Tac p.H323Y PRAD 6 150067084 150067084 + Missense_Mutation SNP C C A TCGA-ZG-A9L4-01A-11D-A41K-08 TCGA-ZG-A9L4-10A-01D-A41N-08 g.chr6:150067084C>A c.235G>T c.(235-237)Gat>Tat p.D79Y READ 6 150063650 150063650 + Missense_Mutation SNP A A T TCGA-AH-6544-01A-11D-1826-10 TCGA-AH-6544-10A-01D-1826-10 g.chr6:150063650A>T c.378T>A c.(376-378)agT>agA p.S126R SKCM 6 150057737 150057737 + Silent SNP G G A TCGA-EE-A3AA-06A-11D-A196-08 TCGA-EE-A3AA-10A-01D-A198-08 g.chr6:150057737G>A c.660C>T c.(658-660)ctC>ctT p.L220L SKCM 6 150059891 150059891 + Missense_Mutation SNP G G A TCGA-D3-A3C7-06A-11D-A196-08 TCGA-D3-A3C7-10A-01D-A198-08 g.chr6:150059891G>A c.526C>T c.(526-528)Cat>Tat p.H176Y

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-US 6 150048189 150048189 single base substitution C T 3_prime_UTR_variant BLCA-US 6 150048189 150048189 single base substitution C T downstream_gene_variant BLCA-US 6 150048189 150048189 single base substitution C T synonymous_variant V257V 771G>A BLCA-US 6 150048189 150048189 single base substitution C T synonymous_variant V353V 1059G>A BLCA-US 6 150059906 150059906 single base substitution C G downstream_gene_variant BLCA-US 6 150059906 150059906 single base substitution C G exon_variant BLCA-US 6 150059906 150059906 single base substitution C G intron_variant BLCA-US 6 150059906 150059906 single base substitution C G missense_variant D171H 511G>C BLCA-US 6 150059906 150059906 single base substitution C G missense_variant D178H 532G>C BLCA-US 6 150067104 150067104 single base substitution C G exon_variant BLCA-US 6 150067104 150067104 single base substitution C G missense_variant R133T 398G>C BLCA-US 6 150067104 150067104 single base substitution C G missense_variant R72T 215G>C BLCA-US 6 150067104 150067104 single base substitution C G missense_variant R79T 236G>C BRCA-EU 6 150041820 150041820 single base substitution A G downstream_gene_variant BRCA-EU 6 150045193 150045193 single base substitution G T downstream_gene_variant BRCA-EU 6 150047056 150047056 single base substitution T C 3_prime_UTR_variant BRCA-EU 6 150047056 150047056 single base substitution T C downstream_gene_variant BRCA-EU 6 150047056 150047056 single base substitution T C intron_variant BRCA-EU 6 150050397 150050397 single base substitution G T downstream_gene_variant BRCA-EU 6 150050397 150050397 single base substitution G T intron_variant BRCA-EU 6 150051214 150051214 single base substitution C T downstream_gene_variant BRCA-EU 6 150051214 150051214 single base substitution C T intron_variant BRCA-EU 6 150051504 150051504 single base substitution C A downstream_gene_variant BRCA-EU 6 150051504 150051504 single base substitution C A intron_variant BRCA-EU 6 150051585 150051585 single base substitution C G downstream_gene_variant BRCA-EU 6 150051585 150051585 single base substitution C G intron_variant BRCA-EU 6 150051852 150051852 single base substitution A G downstream_gene_variant BRCA-EU 6 150051852 150051852 single base substitution A G intron_variant BRCA-EU 6 150053575 150053575 single base substitution C G intron_variant BRCA-EU 6 150054034 150054034 deletion of <=200bp A - intron_variant BRCA-EU 6 150055145 150055145 single base substitution C A downstream_gene_variant BRCA-EU 6 150055145 150055145 single base substitution C A intron_variant BRCA-EU 6 150056019 150056019 single base substitution C G downstream_gene_variant BRCA-EU 6 150056019 150056019 single base substitution C G intron_variant BRCA-EU 6 150056074 150056074 deletion of <=200bp A - downstream_gene_variant BRCA-EU 6 150056074 150056074 deletion of <=200bp A - intron_variant BRCA-EU 6 150057031 150057031 single base substitution C G downstream_gene_variant BRCA-EU 6 150057031 150057031 single base substitution C G intron_variant BRCA-EU 6 150057415 150057415 deletion of <=200bp A - downstream_gene_variant BRCA-EU 6 150057415 150057415 deletion of <=200bp A - intron_variant BRCA-EU 6 150057780 150057780 single base substitution A C downstream_gene_variant BRCA-EU 6 150057780 150057780 single base substitution A C intron_variant BRCA-EU 6 150057941 150057941 single base substitution C T downstream_gene_variant BRCA-EU 6 150057941 150057941 single base substitution C T intron_variant BRCA-EU 6 150058042 150058042 single base substitution C G downstream_gene_variant BRCA-EU 6 150058042 150058042 single base substitution C G intron_variant BRCA-EU 6 150058118 150058118 single base substitution C T downstream_gene_variant BRCA-EU 6 150058118 150058118 single base substitution C T intron_variant BRCA-EU 6 150058121 150058121 deletion of <=200bp T - downstream_gene_variant BRCA-EU 6 150058121 150058121 deletion of <=200bp T - intron_variant BRCA-EU 6 150058876 150058876 single base substitution C A downstream_gene_variant BRCA-EU 6 150058876 150058876 single base substitution C A intron_variant BRCA-EU 6 150059148 150059148 insertion of <=200bp - A downstream_gene_variant BRCA-EU 6 150059148 150059148 insertion of <=200bp - A intron_variant BRCA-EU 6 150059956 150059956 deletion of <=200bp T - downstream_gene_variant BRCA-EU 6 150059956 150059956 deletion of <=200bp T - intron_variant BRCA-EU 6 150060337 150060337 single base substitution C T downstream_gene_variant BRCA-EU 6 150060337 150060337 single base substitution C T intron_variant BRCA-EU 6 150063119 150063119 single base substitution T C downstream_gene_variant BRCA-EU 6 150063119 150063119 single base substitution T C intron_variant BRCA-EU 6 150063668 150063668 single base substitution G A downstream_gene_variant BRCA-EU 6 150063668 150063668 single base substitution G A exon_variant BRCA-EU 6 150063668 150063668 single base substitution G A intron_variant BRCA-EU 6 150063668 150063668 single base substitution G A synonymous_variant Y120Y 360C>T BRCA-EU 6 150063668 150063668 single base substitution G A synonymous_variant Y127Y 381C>T BRCA-EU 6 150063668 150063668 single base substitution G A synonymous_variant Y181Y 543C>T BRCA-EU 6 150065050 150065050 deletion of <=200bp T - intron_variant BRCA-EU 6 150067859 150067859 single base substitution G C intron_variant BRCA-EU 6 150067859 150067859 single base substitution G C upstream_gene_variant BRCA-EU 6 150068167 150068167 single base substitution C G intron_variant BRCA-EU 6 150068167 150068167 single base substitution C G upstream_gene_variant BRCA-EU 6 150069040 150069040 insertion of <=200bp - T intron_variant BRCA-EU 6 150069040 150069040 insertion of <=200bp - T upstream_gene_variant BRCA-EU 6 150069347 150069347 single base substitution G C intron_variant BRCA-EU 6 150069347 150069347 single base substitution G C upstream_gene_variant BRCA-EU 6 150069920 150069920 single base substitution G T intron_variant BRCA-EU 6 150069920 150069920 single base substitution G T upstream_gene_variant BRCA-EU 6 150070119 150070119 single base substitution G A intron_variant BRCA-EU 6 150070119 150070119 single base substitution G A upstream_gene_variant BRCA-EU 6 150072533 150072533 single base substitution C T upstream_gene_variant BRCA-EU 6 150072743 150072743 single base substitution G C upstream_gene_variant BRCA-EU 6 150075311 150075311 single base substitution A G upstream_gene_variant BRCA-FR 6 150045193 150045193 single base substitution G T downstream_gene_variant BRCA-FR 6 150068167 150068167 single base substitution C G intron_variant BRCA-FR 6 150068167 150068167 single base substitution C G upstream_gene_variant BRCA-FR 6 150070119 150070119 single base substitution G A intron_variant BRCA-FR 6 150070119 150070119 single base substitution G A upstream_gene_variant BRCA-FR 6 150072743 150072743 single base substitution G C upstream_gene_variant BRCA-US 6 150052790 150052790 single base substitution G A 3_prime_UTR_variant BRCA-US 6 150052790 150052790 single base substitution G A missense_variant A195V 584C>T BRCA-US 6 150052790 150052790 single base substitution G A missense_variant A291V 872C>T BRCA-US 6 150059887 150059887 single base substitution G C downstream_gene_variant BRCA-US 6 150059887 150059887 single base substitution G C exon_variant BRCA-US 6 150059887 150059887 single base substitution G C intron_variant BRCA-US 6 150059887 150059887 single base substitution G C missense_variant A177G 530C>G BRCA-US 6 150067514 150067514 single base substitution C A intron_variant BRCA-US 6 150067514 150067514 single base substitution C A splice_region_variant BRCA-US 6 150067514 150067514 single base substitution C A stop_gained E101* 301G>T BRCA-US 6 150067514 150067514 single base substitution C A stop_gained E40* 118G>T BRCA-US 6 150067641 150067641 single base substitution G A 5_prime_UTR_premature_start_codon_gain_variant BRCA-US 6 150067641 150067641 single base substitution G A intron_variant BRCA-US 6 150067641 150067641 single base substitution G A synonymous_variant A58A 174C>T BTCA-JP 6 150067135 150067135 single base substitution C T exon_variant BTCA-JP 6 150067135 150067135 single base substitution C T missense_variant E123K 367G>A BTCA-JP 6 150067135 150067135 single base substitution C T missense_variant E62K 184G>A BTCA-JP 6 150067135 150067135 single base substitution C T missense_variant E69K 205G>A CESC-US 6 150067800 150067800 single base substitution G A intron_variant CESC-US 6 150067800 150067800 single base substitution G A synonymous_variant L5L 15C>T CESC-US 6 150067800 150067800 single base substitution G A upstream_gene_variant CLLE-ES 6 150066392 150066392 single base substitution C T intron_variant COAD-US 6 150048312 150048312 insertion of <=200bp - A 3_prime_UTR_variant COAD-US 6 150048312 150048312 insertion of <=200bp - A downstream_gene_variant COAD-US 6 150048312 150048312 insertion of <=200bp - A frameshift_variant L216L? COAD-US 6 150048312 150048312 insertion of <=200bp - A frameshift_variant L312L? COAD-US 6 150063668 150063668 single base substitution G T downstream_gene_variant COAD-US 6 150063668 150063668 single base substitution G T exon_variant COAD-US 6 150063668 150063668 single base substitution G T intron_variant COAD-US 6 150063668 150063668 single base substitution G T stop_gained Y120* 360C>A COAD-US 6 150063668 150063668 single base substitution G T stop_gained Y127* 381C>A COAD-US 6 150063668 150063668 single base substitution G T stop_gained Y181* 543C>A COCA-CN 6 150054816 150054816 single base substitution A G intron_variant COCA-CN 6 150054982 150054982 single base substitution C T downstream_gene_variant COCA-CN 6 150054982 150054982 single base substitution C T intron_variant COCA-CN 6 150057883 150057883 single base substitution G A downstream_gene_variant COCA-CN 6 150057883 150057883 single base substitution G A intron_variant COCA-CN 6 150063495 150063495 single base substitution G A downstream_gene_variant COCA-CN 6 150063495 150063495 single base substitution G A intron_variant COCA-CN 6 150065487 150065487 single base substitution T C intron_variant COCA-CN 6 150072672 150072672 single base substitution C G upstream_gene_variant EOPC-DE 6 150047801 150047801 single base substitution A G 3_prime_UTR_variant EOPC-DE 6 150047801 150047801 single base substitution A G downstream_gene_variant ESAD-UK 6 150045480 150045480 single base substitution T C 3_prime_UTR_variant ESAD-UK 6 150045480 150045480 single base substitution T C downstream_gene_variant ESAD-UK 6 150051517 150051517 single base substitution T G downstream_gene_variant ESAD-UK 6 150051517 150051517 single base substitution T G intron_variant ESAD-UK 6 150059882 150059882 single base substitution T A downstream_gene_variant ESAD-UK 6 150059882 150059882 single base substitution T A exon_variant ESAD-UK 6 150059882 150059882 single base substitution T A intron_variant ESAD-UK 6 150059882 150059882 single base substitution T A missense_variant T179S 535A>T ESAD-UK 6 150059976 150059976 single base substitution T A downstream_gene_variant ESAD-UK 6 150059976 150059976 single base substitution T A intron_variant ESAD-UK 6 150062319 150062319 insertion of <=200bp - T downstream_gene_variant ESAD-UK 6 150062319 150062319 insertion of <=200bp - T intron_variant ESAD-UK 6 150063390 150063390 single base substitution G A downstream_gene_variant ESAD-UK 6 150063390 150063390 single base substitution G A intron_variant ESAD-UK 6 150063787 150063787 single base substitution T C downstream_gene_variant ESAD-UK 6 150063787 150063787 single base substitution T C intron_variant ESAD-UK 6 150064175 150064175 single base substitution G A downstream_gene_variant ESAD-UK 6 150064175 150064175 single base substitution G A intron_variant ESAD-UK 6 150067551 150067551 single base substitution C T exon_variant ESAD-UK 6 150067551 150067551 single base substitution C T intron_variant ESAD-UK 6 150067551 150067551 single base substitution C T synonymous_variant Q27Q 81G>A ESAD-UK 6 150067551 150067551 single base substitution C T synonymous_variant Q88Q 264G>A ESAD-UK 6 150067584 150067584 single base substitution G C exon_variant ESAD-UK 6 150067584 150067584 single base substitution G C intron_variant ESAD-UK 6 150067584 150067584 single base substitution G C synonymous_variant T16T 48C>G ESAD-UK 6 150067584 150067584 single base substitution G C synonymous_variant T77T 231C>G ESAD-UK 6 150067987 150067987 single base substitution A T intron_variant ESAD-UK 6 150067987 150067987 single base substitution A T upstream_gene_variant ESAD-UK 6 150068149 150068149 single base substitution T C intron_variant ESAD-UK 6 150068149 150068149 single base substitution T C upstream_gene_variant ESAD-UK 6 150069397 150069397 single base substitution A G intron_variant ESAD-UK 6 150069397 150069397 single base substitution A G upstream_gene_variant ESAD-UK 6 150070738 150070738 single base substitution C T exon_variant ESAD-UK 6 150070738 150070738 single base substitution C T upstream_gene_variant ESAD-UK 6 150070989 150070989 single base substitution C T upstream_gene_variant ESAD-UK 6 150071506 150071506 single base substitution C T upstream_gene_variant ESAD-UK 6 150071942 150071942 single base substitution A T upstream_gene_variant ESAD-UK 6 150072745 150072745 single base substitution G T upstream_gene_variant ESCA-CN 6 150067547 150067547 single base substitution C G exon_variant ESCA-CN 6 150067547 150067547 single base substitution C G intron_variant ESCA-CN 6 150067547 150067547 single base substitution C G missense_variant A29P 85G>C ESCA-CN 6 150067547 150067547 single base substitution C G missense_variant A90P 268G>C LAML-KR 6 150059702 150059702 single base substitution C A downstream_gene_variant LAML-KR 6 150059702 150059702 single base substitution C A intron_variant LICA-FR 6 150045328 150045328 single base substitution A T downstream_gene_variant LINC-JP 6 150057784 150057784 single base substitution C G downstream_gene_variant LINC-JP 6 150057784 150057784 single base substitution C G intron_variant LINC-JP 6 150059956 150059956 deletion of <=200bp T - downstream_gene_variant LINC-JP 6 150059956 150059956 deletion of <=200bp T - intron_variant LINC-JP 6 150059962 150059962 single base substitution T C downstream_gene_variant LINC-JP 6 150059962 150059962 single base substitution T C intron_variant LINC-JP 6 150064756 150064756 single base substitution C A downstream_gene_variant LINC-JP 6 150064756 150064756 single base substitution C A intron_variant LINC-JP 6 150064920 150064920 single base substitution T A intron_variant LIRI-JP 6 150041075 150041075 single base substitution T C downstream_gene_variant LIRI-JP 6 150045653 150045660 deletion of <=200bp TAAAGTTG - 3_prime_UTR_variant LIRI-JP 6 150045653 150045660 deletion of <=200bp TAAAGTTG - downstream_gene_variant LIRI-JP 6 150046333 150046333 single base substitution C T 3_prime_UTR_variant LIRI-JP 6 150046333 150046333 single base substitution C T downstream_gene_variant LIRI-JP 6 150046333 150046333 single base substitution C T intron_variant LIRI-JP 6 150047125 150047125 single base substitution T C 3_prime_UTR_variant LIRI-JP 6 150047125 150047125 single base substitution T C downstream_gene_variant LIRI-JP 6 150047125 150047125 single base substitution T C intron_variant LIRI-JP 6 150048600 150048600 single base substitution C G downstream_gene_variant LIRI-JP 6 150048600 150048600 single base substitution C G intron_variant LIRI-JP 6 150048827 150048827 single base substitution T C downstream_gene_variant LIRI-JP 6 150048827 150048827 single base substitution T C intron_variant LIRI-JP 6 150049105 150049105 single base substitution C G downstream_gene_variant LIRI-JP 6 150049105 150049105 single base substitution C G intron_variant LIRI-JP 6 150050806 150050806 single base substitution A T downstream_gene_variant LIRI-JP 6 150050806 150050806 single base substitution A T intron_variant LIRI-JP 6 150052111 150052112 deletion of <=200bp AC - downstream_gene_variant LIRI-JP 6 150052111 150052112 deletion of <=200bp AC - intron_variant LIRI-JP 6 150054399 150054399 single base substitution T G intron_variant LIRI-JP 6 150055907 150055907 single base substitution C T downstream_gene_variant LIRI-JP 6 150055907 150055907 single base substitution C T intron_variant LIRI-JP 6 150056182 150056182 single base substitution G C downstream_gene_variant LIRI-JP 6 150056182 150056182 single base substitution G C intron_variant LIRI-JP 6 150056351 150056351 single base substitution G T downstream_gene_variant LIRI-JP 6 150056351 150056351 single base substitution G T intron_variant LIRI-JP 6 150057339 150057339 single base substitution G T downstream_gene_variant LIRI-JP 6 150057339 150057339 single base substitution G T intron_variant LIRI-JP 6 150057568 150057568 single base substitution T C downstream_gene_variant LIRI-JP 6 150057568 150057568 single base substitution T C intron_variant LIRI-JP 6 150058301 150058301 single base substitution T G downstream_gene_variant LIRI-JP 6 150058301 150058301 single base substitution T G intron_variant LIRI-JP 6 150059613 150059613 single base substitution T C downstream_gene_variant LIRI-JP 6 150059613 150059613 single base substitution T C intron_variant LIRI-JP 6 150062330 150062330 single base substitution C G downstream_gene_variant LIRI-JP 6 150062330 150062330 single base substitution C G intron_variant LIRI-JP 6 150064606 150064606 single base substitution C T downstream_gene_variant LIRI-JP 6 150064606 150064606 single base substitution C T intron_variant LIRI-JP 6 150066598 150066598 single base substitution T G intron_variant LIRI-JP 6 150066732 150066732 single base substitution A C intron_variant LIRI-JP 6 150068918 150068918 single base substitution C T intron_variant LIRI-JP 6 150068918 150068918 single base substitution C T upstream_gene_variant LIRI-JP 6 150069109 150069109 single base substitution G A intron_variant LIRI-JP 6 150069109 150069109 single base substitution G A upstream_gene_variant LIRI-JP 6 150069279 150069279 single base substitution G A intron_variant LIRI-JP 6 150069279 150069279 single base substitution G A upstream_gene_variant LIRI-JP 6 150069583 150069583 single base substitution G T intron_variant LIRI-JP 6 150069583 150069583 single base substitution G T upstream_gene_variant LUSC-KR 6 150047197 150047197 single base substitution T G 3_prime_UTR_variant LUSC-KR 6 150047197 150047197 single base substitution T G downstream_gene_variant LUSC-KR 6 150047197 150047197 single base substitution T G intron_variant LUSC-KR 6 150063938 150063938 single base substitution G T downstream_gene_variant LUSC-KR 6 150063938 150063938 single base substitution G T intron_variant LUSC-KR 6 150064705 150064705 single base substitution C A downstream_gene_variant LUSC-KR 6 150064705 150064705 single base substitution C A intron_variant LUSC-KR 6 150067500 150067500 single base substitution C A intron_variant LUSC-KR 6 150069727 150069727 single base substitution T C intron_variant LUSC-KR 6 150069727 150069727 single base substitution T C upstream_gene_variant LUSC-KR 6 150074052 150074052 single base substitution C G upstream_gene_variant LUSC-KR 6 150074779 150074779 single base substitution T C upstream_gene_variant LUSC-US 6 150067096 150067096 single base substitution C A exon_variant LUSC-US 6 150067096 150067096 single base substitution C A missense_variant G136C 406G>T LUSC-US 6 150067096 150067096 single base substitution C A missense_variant G75C 223G>T LUSC-US 6 150067096 150067096 single base substitution C A missense_variant G82C 244G>T MALY-DE 6 150067090 150067090 single base substitution C A exon_variant MALY-DE 6 150067090 150067090 single base substitution C A missense_variant V138L 412G>T MALY-DE 6 150067090 150067090 single base substitution C A missense_variant V77L 229G>T MALY-DE 6 150067090 150067090 single base substitution C A missense_variant V84L 250G>T MALY-DE 6 150068146 150068146 single base substitution G C intron_variant MALY-DE 6 150068146 150068146 single base substitution G C upstream_gene_variant MELA-AU 6 150040868 150040868 single base substitution C A downstream_gene_variant MELA-AU 6 150041500 150041500 single base substitution G A downstream_gene_variant MELA-AU 6 150042513 150042513 single base substitution C T downstream_gene_variant MELA-AU 6 150043319 150043319 single base substitution C A downstream_gene_variant MELA-AU 6 150043814 150043814 single base substitution C T downstream_gene_variant MELA-AU 6 150043935 150043935 single base substitution G A downstream_gene_variant MELA-AU 6 150044112 150044112 single base substitution C T downstream_gene_variant MELA-AU 6 150044675 150044675 single base substitution A G downstream_gene_variant MELA-AU 6 150045332 150045332 single base substitution G A downstream_gene_variant MELA-AU 6 150045858 150045858 single base substitution T G 3_prime_UTR_variant MELA-AU 6 150045858 150045858 single base substitution T G downstream_gene_variant MELA-AU 6 150045858 150045858 single base substitution T G intron_variant MELA-AU 6 150046273 150046273 single base substitution G A 3_prime_UTR_variant MELA-AU 6 150046273 150046273 single base substitution G A downstream_gene_variant MELA-AU 6 150046273 150046273 single base substitution G A intron_variant MELA-AU 6 150046764 150046764 single base substitution C T 3_prime_UTR_variant MELA-AU 6 150046764 150046764 single base substitution C T downstream_gene_variant MELA-AU 6 150046764 150046764 single base substitution C T intron_variant MELA-AU 6 150047011 150047011 single base substitution G A 3_prime_UTR_variant MELA-AU 6 150047011 150047011 single base substitution G A downstream_gene_variant MELA-AU 6 150047011 150047011 single base substitution G A intron_variant MELA-AU 6 150047626 150047626 single base substitution G A 3_prime_UTR_variant MELA-AU 6 150047626 150047626 single base substitution G A downstream_gene_variant MELA-AU 6 150047705 150047705 single base substitution G A 3_prime_UTR_variant MELA-AU 6 150047705 150047705 single base substitution G A downstream_gene_variant MELA-AU 6 150048674 150048674 single base substitution A T downstream_gene_variant MELA-AU 6 150048674 150048674 single base substitution A T intron_variant MELA-AU 6 150049132 150049132 single base substitution G A downstream_gene_variant MELA-AU 6 150049132 150049132 single base substitution G A intron_variant MELA-AU 6 150049504 150049504 single base substitution G A downstream_gene_variant MELA-AU 6 150049504 150049504 single base substitution G A intron_variant MELA-AU 6 150049504 150049504 single base substitution G T downstream_gene_variant MELA-AU 6 150049504 150049504 single base substitution G T intron_variant MELA-AU 6 150051219 150051219 single base substitution C T downstream_gene_variant MELA-AU 6 150051219 150051219 single base substitution C T intron_variant MELA-AU 6 150052161 150052161 single base substitution G A downstream_gene_variant MELA-AU 6 150052161 150052161 single base substitution G A intron_variant MELA-AU 6 150052464 150052464 single base substitution G A downstream_gene_variant MELA-AU 6 150052464 150052464 single base substitution G A intron_variant MELA-AU 6 150052700 150052700 single base substitution A G 3_prime_UTR_variant MELA-AU 6 150052700 150052700 single base substitution A G downstream_gene_variant MELA-AU 6 150052700 150052700 single base substitution A G intron_variant MELA-AU 6 150052703 150052703 single base substitution A T 3_prime_UTR_variant MELA-AU 6 150052703 150052703 single base substitution A T intron_variant MELA-AU 6 150053334 150053334 single base substitution A T intron_variant MELA-AU 6 150053957 150053957 single base substitution G A intron_variant MELA-AU 6 150054661 150054661 single base substitution A C intron_variant MELA-AU 6 150054939 150054939 single base substitution C T downstream_gene_variant MELA-AU 6 150054939 150054939 single base substitution C T intron_variant MELA-AU 6 150054994 150054994 single base substitution C T downstream_gene_variant MELA-AU 6 150054994 150054994 single base substitution C T intron_variant MELA-AU 6 150055095 150055095 single base substitution G A downstream_gene_variant MELA-AU 6 150055095 150055095 single base substitution G A intron_variant MELA-AU 6 150056039 150056039 single base substitution G A downstream_gene_variant MELA-AU 6 150056039 150056039 single base substitution G A intron_variant MELA-AU 6 150056326 150056326 single base substitution G A downstream_gene_variant MELA-AU 6 150056326 150056326 single base substitution G A intron_variant MELA-AU 6 150057540 150057540 single base substitution G A downstream_gene_variant MELA-AU 6 150057540 150057540 single base substitution G A intron_variant MELA-AU 6 150057737 150057737 single base substitution G A 3_prime_UTR_variant MELA-AU 6 150057737 150057737 single base substitution G A downstream_gene_variant MELA-AU 6 150057737 150057737 single base substitution G A exon_variant MELA-AU 6 150057737 150057737 single base substitution G A intron_variant MELA-AU 6 150057737 150057737 single base substitution G A missense_variant S236F 707C>T MELA-AU 6 150057737 150057737 single base substitution G A synonymous_variant L220L 660C>T MELA-AU 6 150059078 150059078 single base substitution C T downstream_gene_variant MELA-AU 6 150059078 150059078 single base substitution C T intron_variant MELA-AU 6 150060556 150060556 single base substitution G A downstream_gene_variant MELA-AU 6 150060556 150060556 single base substitution G A intron_variant MELA-AU 6 150061526 150061526 single base substitution G A downstream_gene_variant MELA-AU 6 150061526 150061526 single base substitution G A intron_variant MELA-AU 6 150061800 150061800 single base substitution G A downstream_gene_variant MELA-AU 6 150061800 150061800 single base substitution G A intron_variant MELA-AU 6 150061831 150061831 single base substitution T A downstream_gene_variant MELA-AU 6 150061831 150061831 single base substitution T A intron_variant MELA-AU 6 150061865 150061865 single base substitution T G downstream_gene_variant MELA-AU 6 150061865 150061865 single base substitution T G intron_variant MELA-AU 6 150062123 150062123 single base substitution C T downstream_gene_variant MELA-AU 6 150062123 150062123 single base substitution C T intron_variant MELA-AU 6 150062371 150062371 single base substitution G A downstream_gene_variant MELA-AU 6 150062371 150062371 single base substitution G A intron_variant MELA-AU 6 150063368 150063368 single base substitution G A downstream_gene_variant MELA-AU 6 150063368 150063368 single base substitution G A intron_variant MELA-AU 6 150063560 150063560 single base substitution G A downstream_gene_variant MELA-AU 6 150063560 150063560 single base substitution G A exon_variant MELA-AU 6 150063560 150063560 single base substitution G A intron_variant MELA-AU 6 150063560 150063560 single base substitution G A synonymous_variant F156F 468C>T MELA-AU 6 150063560 150063560 single base substitution G A synonymous_variant F163F 489C>T MELA-AU 6 150063560 150063560 single base substitution G A synonymous_variant F217F 651C>T MELA-AU 6 150065748 150065748 single base substitution T A intron_variant MELA-AU 6 150066926 150066926 single base substitution G A intron_variant MELA-AU 6 150067148 150067148 single base substitution A T exon_variant MELA-AU 6 150067148 150067148 single base substitution A T synonymous_variant S118S 354T>A MELA-AU 6 150067148 150067148 single base substitution A T synonymous_variant S57S 171T>A MELA-AU 6 150067148 150067148 single base substitution A T synonymous_variant S64S 192T>A MELA-AU 6 150067696 150067696 single base substitution C T 5_prime_UTR_variant MELA-AU 6 150067696 150067696 single base substitution C T intron_variant MELA-AU 6 150067696 150067696 single base substitution C T missense_variant R40K 119G>A MELA-AU 6 150067696 150067696 single base substitution C T upstream_gene_variant MELA-AU 6 150074921 150074921 single base substitution C T upstream_gene_variant ORCA-IN 6 150042097 150042097 single base substitution G A downstream_gene_variant ORCA-IN 6 150054293 150054293 single base substitution G A intron_variant ORCA-IN 6 150054404 150054404 single base substitution C A intron_variant OV-AU 6 150041565 150041565 single base substitution T A downstream_gene_variant OV-AU 6 150066190 150066190 single base substitution G A intron_variant PACA-AU 6 150047330 150047330 single base substitution T G 3_prime_UTR_variant PACA-AU 6 150047330 150047330 single base substitution T G downstream_gene_variant PACA-AU 6 150047330 150047330 single base substitution T G intron_variant PACA-AU 6 150050316 150050316 single base substitution A G downstream_gene_variant PACA-AU 6 150050316 150050316 single base substitution A G intron_variant PACA-AU 6 150063075 150063075 single base substitution A T downstream_gene_variant PACA-AU 6 150063075 150063075 single base substitution A T intron_variant PACA-AU 6 150064705 150064705 single base substitution C T downstream_gene_variant PACA-AU 6 150064705 150064705 single base substitution C T intron_variant PACA-AU 6 150067882 150067882 single base substitution C G intron_variant PACA-AU 6 150067882 150067882 single base substitution C G upstream_gene_variant PACA-AU 6 150070844 150070844 single base substitution G T upstream_gene_variant PACA-AU 6 150071868 150071868 single base substitution C G upstream_gene_variant PACA-CA 6 150042679 150042679 single base substitution C T downstream_gene_variant PACA-CA 6 150043581 150043581 single base substitution G C downstream_gene_variant PACA-CA 6 150043836 150043836 single base substitution A C downstream_gene_variant PACA-CA 6 150048208 150048208 single base substitution G A 3_prime_UTR_variant PACA-CA 6 150048208 150048208 single base substitution G A downstream_gene_variant PACA-CA 6 150048208 150048208 single base substitution G A missense_variant P251L 752C>T PACA-CA 6 150048208 150048208 single base substitution G A missense_variant P347L 1040C>T PACA-CA 6 150052159 150052159 single base substitution T G downstream_gene_variant PACA-CA 6 150052159 150052159 single base substitution T G intron_variant PACA-CA 6 150053328 150053328 single base substitution A G intron_variant PACA-CA 6 150058334 150058334 single base substitution C T downstream_gene_variant PACA-CA 6 150058334 150058334 single base substitution C T intron_variant PACA-CA 6 150058827 150058827 single base substitution G C downstream_gene_variant PACA-CA 6 150058827 150058827 single base substitution G C intron_variant PACA-CA 6 150060186 150060186 single base substitution G T downstream_gene_variant PACA-CA 6 150060186 150060186 single base substitution G T intron_variant PACA-CA 6 150060848 150060848 single base substitution C T downstream_gene_variant PACA-CA 6 150060848 150060848 single base substitution C T intron_variant PACA-CA 6 150064219 150064219 single base substitution T C downstream_gene_variant PACA-CA 6 150064219 150064219 single base substitution T C intron_variant PACA-CA 6 150064461 150064461 single base substitution C T downstream_gene_variant PACA-CA 6 150064461 150064461 single base substitution C T intron_variant PACA-CA 6 150064560 150064560 single base substitution C A downstream_gene_variant PACA-CA 6 150064560 150064560 single base substitution C A intron_variant PACA-CA 6 150067652 150067652 single base substitution G A 5_prime_UTR_variant PACA-CA 6 150067652 150067652 single base substitution G A intron_variant PACA-CA 6 150067652 150067652 single base substitution G A missense_variant P55S 163C>T PACA-CA 6 150068221 150068221 single base substitution T C intron_variant PACA-CA 6 150068221 150068221 single base substitution T C upstream_gene_variant PACA-CA 6 150069464 150069464 insertion of <=200bp - A intron_variant PACA-CA 6 150069464 150069464 insertion of <=200bp - A upstream_gene_variant PACA-CA 6 150072163 150072163 deletion of <=200bp T - upstream_gene_variant PACA-CA 6 150073418 150073418 single base substitution C T upstream_gene_variant PACA-CA 6 150073987 150073987 single base substitution A T upstream_gene_variant PACA-CA 6 150074486 150074486 single base substitution G T upstream_gene_variant PAEN-AU 6 150052680 150052680 single base substitution T C 3_prime_UTR_variant PAEN-AU 6 150052680 150052680 single base substitution T C downstream_gene_variant PAEN-AU 6 150052680 150052680 single base substitution T C intron_variant PAEN-AU 6 150065314 150065314 single base substitution C T intron_variant PAEN-IT 6 150060108 150060108 single base substitution C A downstream_gene_variant PAEN-IT 6 150060108 150060108 single base substitution C A intron_variant PAEN-IT 6 150062884 150062884 single base substitution G A downstream_gene_variant PAEN-IT 6 150062884 150062884 single base substitution G A intron_variant PAEN-IT 6 150063596 150063596 single base substitution G T downstream_gene_variant PAEN-IT 6 150063596 150063596 single base substitution G T exon_variant PAEN-IT 6 150063596 150063596 single base substitution G T intron_variant PAEN-IT 6 150063596 150063596 single base substitution G T synonymous_variant I144I 432C>A PAEN-IT 6 150063596 150063596 single base substitution G T synonymous_variant I151I 453C>A PAEN-IT 6 150063596 150063596 single base substitution G T synonymous_variant I205I 615C>A PBCA-DE 6 150064564 150064564 single base substitution T A downstream_gene_variant PBCA-DE 6 150064564 150064564 single base substitution T A intron_variant PBCA-DE 6 150068005 150068005 single base substitution G A intron_variant PBCA-DE 6 150068005 150068005 single base substitution G A upstream_gene_variant PRAD-CA 6 150069074 150069074 single base substitution A C intron_variant PRAD-CA 6 150069074 150069074 single base substitution A C upstream_gene_variant PRAD-CA 6 150071049 150071049 single base substitution A G upstream_gene_variant PRAD-UK 6 150051402 150051402 single base substitution C G downstream_gene_variant PRAD-UK 6 150051402 150051402 single base substitution C G intron_variant PRAD-UK 6 150052390 150052390 single base substitution A C downstream_gene_variant PRAD-UK 6 150052390 150052390 single base substitution A C intron_variant PRAD-UK 6 150062484 150062494 deletion of <=200bp ATTTTTAGTAG - downstream_gene_variant PRAD-UK 6 150062484 150062494 deletion of <=200bp ATTTTTAGTAG - intron_variant PRAD-UK 6 150064221 150064221 single base substitution A C downstream_gene_variant PRAD-UK 6 150064221 150064221 single base substitution A C intron_variant PRAD-UK 6 150067655 150067655 single base substitution C T 5_prime_UTR_variant PRAD-UK 6 150067655 150067655 single base substitution C T intron_variant PRAD-UK 6 150067655 150067655 single base substitution C T missense_variant V54I 160G>A PRAD-UK 6 150073150 150073150 single base substitution C T upstream_gene_variant PRAD-US 6 150048281 150048281 single base substitution G A 3_prime_UTR_variant PRAD-US 6 150048281 150048281 single base substitution G A downstream_gene_variant PRAD-US 6 150048281 150048281 single base substitution G A missense_variant H227Y 679C>T PRAD-US 6 150048281 150048281 single base substitution G A missense_variant H323Y 967C>T READ-US 6 150059872 150059872 single base substitution C T 3_prime_UTR_variant READ-US 6 150059872 150059872 single base substitution C T downstream_gene_variant READ-US 6 150059872 150059872 single base substitution C T intron_variant READ-US 6 150059872 150059872 single base substitution C T missense_variant R182Q 545G>A READ-US 6 150063650 150063650 single base substitution A T downstream_gene_variant READ-US 6 150063650 150063650 single base substitution A T exon_variant READ-US 6 150063650 150063650 single base substitution A T intron_variant READ-US 6 150063650 150063650 single base substitution A T missense_variant S126R 378T>A READ-US 6 150063650 150063650 single base substitution A T missense_variant S133R 399T>A READ-US 6 150063650 150063650 single base substitution A T missense_variant S187R 561T>A RECA-EU 6 150042716 150042716 single base substitution G T downstream_gene_variant RECA-EU 6 150050611 150050611 single base substitution A C downstream_gene_variant RECA-EU 6 150050611 150050611 single base substitution A C intron_variant SKCA-BR 6 150043855 150043855 single base substitution G A downstream_gene_variant SKCA-BR 6 150045493 150045494 deletion of <=200bp TG - 3_prime_UTR_variant SKCA-BR 6 150045493 150045494 deletion of <=200bp TG - downstream_gene_variant SKCA-BR 6 150051785 150051785 single base substitution G A downstream_gene_variant SKCA-BR 6 150051785 150051785 single base substitution G A intron_variant SKCA-BR 6 150052077 150052077 insertion of <=200bp - CA downstream_gene_variant SKCA-BR 6 150052077 150052077 insertion of <=200bp - CA intron_variant SKCA-BR 6 150053742 150053742 single base substitution G A intron_variant SKCA-BR 6 150061856 150061856 single base substitution G A downstream_gene_variant SKCA-BR 6 150061856 150061856 single base substitution G A intron_variant SKCA-BR 6 150064899 150064899 single base substitution G A intron_variant SKCA-BR 6 150066102 150066102 single base substitution C T intron_variant SKCA-BR 6 150070577 150070577 single base substitution A C exon_variant SKCA-BR 6 150070577 150070577 single base substitution A C upstream_gene_variant SKCA-BR 6 150071025 150071025 single base substitution A G upstream_gene_variant SKCA-BR 6 150072678 150072678 single base substitution C A upstream_gene_variant SKCM-US 6 150057737 150057737 single base substitution G A 3_prime_UTR_variant SKCM-US 6 150057737 150057737 single base substitution G A downstream_gene_variant SKCM-US 6 150057737 150057737 single base substitution G A exon_variant SKCM-US 6 150057737 150057737 single base substitution G A intron_variant SKCM-US 6 150057737 150057737 single base substitution G A missense_variant S236F 707C>T SKCM-US 6 150057737 150057737 single base substitution G A synonymous_variant L220L 660C>T SKCM-US 6 150059891 150059891 single base substitution G A downstream_gene_variant SKCM-US 6 150059891 150059891 single base substitution G A exon_variant SKCM-US 6 150059891 150059891 single base substitution G A intron_variant SKCM-US 6 150059891 150059891 single base substitution G A missense_variant H176Y 526C>T STAD-US 6 150048162 150048162 single base substitution A T 3_prime_UTR_variant STAD-US 6 150048162 150048162 single base substitution A T downstream_gene_variant STAD-US 6 150048162 150048162 single base substitution A T stop_gained C266* 798T>A STAD-US 6 150048162 150048162 single base substitution A T stop_gained C362* 1086T>A STAD-US 6 150048223 150048223 single base substitution A G 3_prime_UTR_variant STAD-US 6 150048223 150048223 single base substitution A G downstream_gene_variant STAD-US 6 150048223 150048223 single base substitution A G missense_variant I246T 737T>C STAD-US 6 150048223 150048223 single base substitution A G missense_variant I342T 1025T>C STAD-US 6 150067127 150067127 single base substitution G A exon_variant STAD-US 6 150067127 150067127 single base substitution G A synonymous_variant D125D 375C>T STAD-US 6 150067127 150067127 single base substitution G A synonymous_variant D64D 192C>T STAD-US 6 150067127 150067127 single base substitution G A synonymous_variant D71D 213C>T STAD-US 6 150071036 150071036 single base substitution C T upstream_gene_variant THCA-SA 6 150067675 150067675 single base substitution A G 5_prime_UTR_variant THCA-SA 6 150067675 150067675 single base substitution A G intron_variant THCA-SA 6 150067675 150067675 single base substitution A G missense_variant V47A 140T>C THCA-SA 6 150067675 150067675 single base substitution A G upstream_gene_variant UCEC-US 6 150048232 150048232 single base substitution C T 3_prime_UTR_variant UCEC-US 6 150048232 150048232 single base substitution C T downstream_gene_variant UCEC-US 6 150048232 150048232 single base substitution C T missense_variant R243Q 728G>A UCEC-US 6 150048232 150048232 single base substitution C T missense_variant R339Q 1016G>A UCEC-US 6 150063573 150063573 single base substitution C T downstream_gene_variant UCEC-US 6 150063573 150063573 single base substitution C T exon_variant UCEC-US 6 150063573 150063573 single base substitution C T intron_variant UCEC-US 6 150063573 150063573 single base substitution C T missense_variant R152Q 455G>A UCEC-US 6 150063573 150063573 single base substitution C T missense_variant R159Q 476G>A UCEC-US 6 150063573 150063573 single base substitution C T missense_variant R213Q 638G>A UCEC-US 6 150063596 150063596 single base substitution G A downstream_gene_variant UCEC-US 6 150063596 150063596 single base substitution G A exon_variant UCEC-US 6 150063596 150063596 single base substitution G A intron_variant UCEC-US 6 150063596 150063596 single base substitution G A synonymous_variant I144I 432C>T UCEC-US 6 150063596 150063596 single base substitution G A synonymous_variant I151I 453C>T UCEC-US 6 150063596 150063596 single base substitution G A synonymous_variant I205I 615C>T

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand TCGA-G2-A2EF-01 COSM1311661 c.1059G>A p.V353V Substitution - coding silent 6:149727053-149727053 - tumor_4107137 COSM3357962 c.229G>T p.V77L Substitution - Missense 6:149745954-149745954 - pfg060T COSM4762515 c.709G>A p.G237S Substitution - Missense 6:149736552-149736552 - TCGA-CG-4466-01 COSM3859050 c.1086T>A p.C362* Substitution - Nonsense 6:149727026-149727026 - 85 COSM5011691 c.67C>A p.P23T Substitution - Missense 6:149746429-149746429 - SNU-C2B COSM3018868 c.115A>G p.N39D Substitution - Missense 6:149746381-149746381 - HN_0-046 COSM124890 c.623C>G p.S208C Substitution - Missense 6:149738658-149738658 - TCGA-A7-A5ZV-01 COSM3829282 c.530C>G p.A177G Substitution - Missense 6:149738751-149738751 - CSCC-15-T COSM4514250 c.969C>G p.H323Q Substitution - Missense 6:149727143-149727143 - TCGA-EE-A3AA-06 COSM3621406 c.660C>T p.L220L Substitution - coding silent 6:149736601-149736601 - 021T COSM1727992 c.751A>T p.T251S Substitution - Missense 6:149736510-149736510 - PTC-14C COSM740635 c.223G>T p.G75C Substitution - Missense 6:149745960-149745960 - LC_C9 COSM1187177 c.1045A>T p.R349W Substitution - Missense 6:149727067-149727067 - PDA_045 COSM5000459 c.529G>T p.A177S Substitution - Missense 6:149738752-149738752 - ESCC-243T COSM3941551 c.85G>C p.A29P Substitution - Missense 6:149746411-149746411 - 587376 COSM1218111 c.12T>G p.I4M Substitution - Missense 6:149746484-149746484 - PET100T COSM4963616 c.432C>A p.I144I Substitution - coding silent 6:149742460-149742460 - TCGA-BS-A0UF-01 COSM1074468 c.1016G>A p.R339Q Substitution - Missense 6:149727096-149727096 - TCGA-18-3410-01 COSM740635 c.223G>T p.G75C Substitution - Missense 6:149745960-149745960 - 273T COSM1727368 c.502+1G>A p.? Unknown 6:149742389-149742389 - pfg057T COSM4762514 c.944G>A p.S315N Substitution - Missense 6:149727168-149727168 - PCSI_0090_Pa_P COSM3381459 c.1040C>T p.P347L Substitution - Missense 6:149727072-149727072 - Pat_44_B COSM5869500 c.787G>A p.E263K Substitution - Missense 6:149736474-149736474 - TCGA-AA-3941-01 COSM301449 c.140_141GG>TT p.W47>? Complex 6:149746042-149746043 - TCGA-AH-6544-01 COSM1568015 c.378T>A p.S126R Substitution - Missense 6:149742514-149742514 - Gp2D COSM4628493 c.837C>T p.T279T Substitution - coding silent 6:149731689-149731689 - TCGA-BR-8591-01 COSM3859052 c.192C>T p.D64D Substitution - coding silent 6:149745991-149745991 - S02360 COSM5696249 c.794G>A p.W265* Substitution - Nonsense 6:149731732-149731732 - 227_T COSM3948152 c.253C>G p.Q85E Substitution - Missense 6:149743706-149743706 - TCGA-G4-6588-01 COSM1441142 c.935_936insT p.L312fs*4 Insertion - Frameshift 6:149727176-149727177 - I2L-P25-Tumor-Organoid COSM5357547 c.639-1G>A p.? Unknown 6:149736623-149736623 - PR-09-5702 COSM246143 c.858C>T p.L286L Substitution - coding silent 6:149731668-149731668 - CSCC-11-T COSM4553601 c.595G>T p.D199Y Substitution - Missense 6:149738686-149738686 - 3N05-VS-3T05 COSM4978811 c.278C>T p.S93L Substitution - Missense 6:149743681-149743681 - LP6007520-DNA_A01 COSM4413167 c.81G>A p.Q27Q Substitution - coding silent 6:149746415-149746415 - PT34 COSM5943744 c.717delT p.D239fs*4 Deletion - Frameshift 6:149736544-149736544 - 587376 COSM1218110 c.173A>G p.D58G Substitution - Missense 6:149746010-149746010 - LP6005334-DNA_A04 COSM4412198 c.535A>T p.T179S Substitution - Missense 6:149738746-149738746 - PR-06-1749 COSM246142 c.345G>T p.W115C Substitution - Missense 6:149742547-149742547 - Pat_45_B COSM5869499 c.938C>T p.S313F Substitution - Missense 6:149727174-149727174 - TCGA-AC-A23H-01 COSM3829283 c.118G>T p.E40* Substitution - Nonsense 6:149746378-149746378 - SA223 COSM212513 c.1091T>C p.V364A Substitution - Missense 6:149727021-149727021 - 585265 COSM322150 c.49C>T p.R17C Substitution - Missense 6:149746447-149746447 - 2521262 COSM5891940 c.379C>T p.P127S Substitution - Missense 6:149742513-149742513 - HCC2998 COSM1672834 c.1139C>T p.S380L Substitution - Missense 6:149726973-149726973 - T2963 COSM4708780 c.600C>T p.F200F Substitution - coding silent 6:149738681-149738681 - 108 COSM5016855 c.96C>G p.F32L Substitution - Missense 6:149746400-149746400 - ITNET_0100_T COSM4963616 c.432C>A p.I144I Substitution - coding silent 6:149742460-149742460 - T3724 COSM4708781 c.501A>G p.I167M Substitution - Missense 6:149742391-149742391 - TCGA-FD-A3SO-01 COSM3777185 c.511G>C p.D171H Substitution - Missense 6:149738770-149738770 - 66 COSM5743159 c.1030A>G p.S344G Substitution - Missense 6:149727082-149727082 - PR-00-1165 COSM246141 c.236A>G p.D79G Substitution - Missense 6:149745947-149745947 - 1N62-VS-1T62 COSM4977919 c.343T>A p.W115R Substitution - Missense 6:149742549-149742549 - PCSI_0090_Pa_X COSM3381459 c.1040C>T p.P347L Substitution - Missense 6:149727072-149727072 - BD174T COSM5521350 c.184G>A p.E62K Substitution - Missense 6:149745999-149745999 - SWE-2A COSM1178207 c.656C>A p.P219Q Substitution - Missense 6:149736605-149736605 - TCGA-CF-A1HS-01 COSM421034 c.215G>C p.R72T Substitution - Missense 6:149745968-149745968 - TCGA-B5-A11E-01 COSM1074470 c.432C>T p.I144I Substitution - coding silent 6:149742460-149742460 - HN22PT COSM98188 c.386A>G p.Y129C Substitution - Missense 6:149742506-149742506 - TCGA-EI-6917-01 COSM3430105 c.545G>A p.R182Q Substitution - Missense 6:149738736-149738736 - TCGA-EJ-5519-01 COSM1132018 c.967C>T p.H323Y Substitution - Missense 6:149727145-149727145 - TCGA-AX-A05Z-01 COSM1074469 c.455G>A p.R152Q Substitution - Missense 6:149742437-149742437 - TCGA-D8-A1J8-01 COSM3829281 c.872C>T p.A291V Substitution - Missense 6:149731654-149731654 - TCGA-D3-A3C7-06 COSM3621408 c.526C>T p.H176Y Substitution - Missense 6:149738755-149738755 - TCGA-BR-8372-01 COSM3859051 c.1025T>C p.I342T Substitution - Missense 6:149727087-149727087 - TCGA-AD-6964-01 COSM1441143 c.360C>A p.Y120* Substitution - Nonsense 6:149742532-149742532 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.510375 6q25.1 608141

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C IntronicSNV . c.913+11T>G 6 150052738 CLL A G Missense p.V364A c.1091T>C 6 150048157 BRCA A T Nonsense p.C362* c.1086T>A 6 150048162 STAD C A Missense p.G75C c.223G>T 6 150067096 LUSC C A Missense p.L242F c.726G>T 6 150057671 LUAD C A Missense p.M264I c.792G>T 6 150052870 HNSC C A Synonymous p.P23P c.69G>T 6 150067563 STAD CC AA Missense p.W47F c.140_141delinsTT 6 150067178 COREAD C G Missense p.D79H c.235G>C 6 150067084 BRCA C G Missense p.R72T c.215G>C 6 150067104 BLCA C T 5-UTRSNV . c.1-68G>A 6 150067699 CM C T Synonymous p.V353V c.1059G>A 6 150048189 BLCA G A 5-UTRSNV . c.1-10C>T 6 150067641 BRCA G A Missense p.H176Y c.526C>T 6 150059891 CM G A Missense p.H323Y c.967C>T 6 150048281 PRAD G A Missense p.R17C c.49C>T 6 150067583 SCLC G A Missense p.T179I c.536C>T 6 150059881 CM G A Synonymous p.L220L c.660C>T 6 150057737 CM G C Missense p.L277V c.829C>G 6 150052833 HNSC G C Missense p.S208C c.623C>G 6 150059794 HNSC TAAAGTTG - 3-UTRDeletion . c.1140+2449_1140+2456delAACTTTAT 6 150045652 HC T A Missense p.N106I c.317A>T 6 150064778 LUAD T C Missense p.T235A c.703A>G 6 150057694 LUAD