PTM - dbPAF Gene Name UniProt ID Position Type Species SORBS3; SCAM1 O60504 217 S Homo sapiens(Human) SORBS3; SCAM1 O60504 218 T Homo sapiens(Human) SORBS3; SCAM1 O60504 24 S Homo sapiens(Human) SORBS3; SCAM1 O60504 268 S Homo sapiens(Human) SORBS3; SCAM1 O60504 299 S Homo sapiens(Human) SORBS3; SCAM1 O60504 337 S Homo sapiens(Human) SORBS3; SCAM1 O60504 339 S Homo sapiens(Human) SORBS3; SCAM1 O60504 348 S Homo sapiens(Human) SORBS3; SCAM1 O60504 358 Y Homo sapiens(Human) SORBS3; SCAM1 O60504 361 S Homo sapiens(Human) SORBS3; SCAM1 O60504 362 T Homo sapiens(Human) SORBS3; SCAM1 O60504 366 S Homo sapiens(Human) SORBS3; SCAM1 O60504 368 S Homo sapiens(Human) SORBS3; SCAM1 O60504 373 S Homo sapiens(Human) SORBS3; SCAM1 O60504 395 S Homo sapiens(Human) SORBS3; SCAM1 O60504 408 Y Homo sapiens(Human) SORBS3; SCAM1 O60504 497 T Homo sapiens(Human) SORBS3; SCAM1 O60504 529 T Homo sapiens(Human) SORBS3; SCAM1 O60504 530 S Homo sapiens(Human) SORBS3; SCAM1 O60504 534 T Homo sapiens(Human) SORBS3; SCAM1 O60504 539 S Homo sapiens(Human) SORBS3; SCAM1 O60504 544 S Homo sapiens(Human) SORBS3; SCAM1 O60504 545 S Homo sapiens(Human) SORBS3; SCAM1 O60504 547 S Homo sapiens(Human) SORBS3; SCAM1 O60504 551 S Homo sapiens(Human) SORBS3; SCAM1 O60504 562 T Homo sapiens(Human) SORBS3; SCAM1 O60504 563 S Homo sapiens(Human) SORBS3; SCAM1 O60504 585 T Homo sapiens(Human) SORBS3; SCAM1 O60504 597 S Homo sapiens(Human) SORBS3; SCAM1 O60504 604 T Homo sapiens(Human) SORBS3; SCAM1 O60504 605 S Homo sapiens(Human) SORBS3; SCAM1 O60504 606 S Homo sapiens(Human) SORBS3; SCAM1 O60504 609 T Homo sapiens(Human) SORBS3; SCAM1 O60504 610 S Homo sapiens(Human) SORBS3; SCAM1 O60504 615 T Homo sapiens(Human)

PTM - PhosSNP Gene Name dbSNP ID Gene Mutation AA Mutation Mutation Position Code Peptide Score Modification Type SORBS3; SCAM1 rs34059820 CGC->CAC R->H 203 S RSARHPSSPSALRSP 545 Phosphorylation TypeIII- SORBS3; SCAM1 rs34059820 CGC->CAC R->H 545 S RSARHPSSPSALRSP 545 Phosphorylation TypeIII-

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O60504 K112-ac Acetylation ATWTKDSkRRDkRWV O60504 K116-ac Acetylation KDSkRRDkRWVKYEG O60504 R594-m1 Methylation GPALSHSrGPsHPLD O60504 S13-p Phosphorylation RSLRAGLsLDDFIPG O60504 T64-p Phosphorylation TVCNGGYtPRRDASQ O60504 T80-p Phosphorylation PDPAWYQtWPGPGSK O60504 S217-p Phosphorylation NYRPGAFstVLQPSN O60504 T218-p Phosphorylation YRPGAFstVLQPSNQ O60504 S283-p Phosphorylation ERELAELsAELDKDL O60504 S299-p Phosphorylation AIETRLPsPKssPAP O60504 S302-p Phosphorylation TRLPsPKssPAPRRA O60504 S303-p Phosphorylation RLPsPKssPAPRRAP O60504 S348-p Phosphorylation HKMADGGsPFLGRRD O60504 Y358-p Phosphorylation LGRRDFVyPSstRDP O60504 S361-p Phosphorylation RDFVyPSstRDPsAS O60504 T362-p Phosphorylation DFVyPSstRDPsASN O60504 S366-p Phosphorylation PSstRDPsASNGGGs O60504 S373-p Phosphorylation sASNGGGsPARREEK O60504 S395-p Phosphorylation KFDFQAQsPKELTLQ O60504 Y408-p Phosphorylation LQKGDIVyIHKEVDK O60504 T497-p Phosphorylation NWYEGRItGTGRQGI O60504 T529-p Phosphorylation DDGPQLPtsPRLTAA O60504 S530-p Phosphorylation DGPQLPtsPRLTAAA O60504 S539-p Phosphorylation RLTAAARsARHPssP O60504 S544-p Phosphorylation ARsARHPssPsALRs O60504 S545-p Phosphorylation RsARHPssPsALRsP O60504 S547-p Phosphorylation ARHPssPsALRsPAD O60504 S551-p Phosphorylation ssPsALRsPADPIDL O60504 T562-p Phosphorylation PIDLGGQtsPRRTGF O60504 S563-p Phosphorylation IDLGGQtsPRRTGFS O60504 T585-p Phosphorylation PQTQNLGtPGPALSH O60504 S597-p Phosphorylation LSHSrGPsHPLDLGt O60504 T604-p Phosphorylation sHPLDLGtssPNtsQ O60504 S605-p Phosphorylation HPLDLGtssPNtsQI O60504 S606-p Phosphorylation PLDLGtssPNtsQIH O60504 T609-p Phosphorylation LGtssPNtsQIHWtP O60504 S610-p Phosphorylation GtssPNtsQIHWtPY O60504 T615-p Phosphorylation NtsQIHWtPYRAMYQ

PTM - dbPTM UniProt ID Position Code Type Resources References O60504 217 S Phosphorylation Swiss-Prot 1010711 18691976 O60504 218 T Phosphorylation Swiss-Prot 1010711 18691976 O60504 348 S Phosphorylation Swiss-Prot 1010711 17081983;19369195 O60504 395 S Phosphorylation Swiss-Prot 1010711 18669648;18691976 O60504 529 T Phosphorylation Swiss-Prot 1010711 18187866 O60504 530 S Phosphorylation Swiss-Prot 1010711 15302935;16964243;18187866;18669648;18691976;19369195;19413330;19690332 O60504 545 S Phosphorylation Swiss-Prot 1010711 17081983;18669648;18691976 O60504 551 S Phosphorylation Swiss-Prot 1010711 17081983;18669648 O60504 563 S Phosphorylation Swiss-Prot 1010711 15302935;18220336;18669648;18691976;19369195;19413330;19690332 O60504 348 S Phosphorylation PhosphoELM.10011 17081983 O60504 395 S Phosphorylation PhosphoELM.10011 18669648 O60504 530 S Phosphorylation PhosphoELM.10011 18669648;16964243;17081983 O60504 544 S Phosphorylation PhosphoELM.10011 18669648 O60504 545 S Phosphorylation PhosphoELM.10011 18669648;17081983 O60504 547 S Phosphorylation PhosphoELM.10011 18669648 O60504 551 S Phosphorylation PhosphoELM.10011 18669648 O60504 563 S Phosphorylation PhosphoELM.10011 18669648;18220336 O60504 606 S Phosphorylation PhosphoELM.10011 18669648 O60504 529 T Phosphorylation PhosphoELM.10011 18669648 O60504 562 T Phosphorylation PhosphoELM.10011 18669648 O60504 615 T Phosphorylation PhosphoELM.10011 18669648 O60504 217 S Phosphorylation Phosphositeplus.1010730 18691976 O60504 348 S Phosphorylation Phosphositeplus.1010730 17081983;19362540;19369195;19664995;20068231;20363803;21406692;22115753 O60504 373 S Phosphorylation Phosphositeplus.1010730 20068231;20363803 O60504 395 S Phosphorylation Phosphositeplus.1010730 17446864;18669648;18691976;19276368;19664994;20068231 O60504 530 S Phosphorylation Phosphositeplus.1010730 15302935;16964243;18187866;18669648;18691976;19362540;19369195;19415658;19664994;19664995;19690332;20068231;20562096;21406692;21659604 O60504 544 S Phosphorylation Phosphositeplus.1010730 18669648;21406692 O60504 545 S Phosphorylation Phosphositeplus.1010730 18669648;18691976;19276368;20068231;21406692 O60504 547 S Phosphorylation Phosphositeplus.1010730 18669648;19276368 O60504 551 S Phosphorylation Phosphositeplus.1010730 18669648;19276368;19690332;20068231 O60504 563 S Phosphorylation Phosphositeplus.1010730 15302935;18220336;18491316;18669648;18691976;18847512;19276368;19362540;19369195;19415658;19664994;19664995;19690332;20068231;20166139;20562096;21406692 O60504 606 S Phosphorylation Phosphositeplus.1010730 18669648 O60504 218 T Phosphorylation Phosphositeplus.1010730 18691976 O60504 529 T Phosphorylation Phosphositeplus.1010730 16964243;18187866;18669648;19415658;19664995;20068231 O60504 562 T Phosphorylation Phosphositeplus.1010730 18847512;19276368;19664995;21406692 O60504 24 S Phosphorylation HPRD 9.0 17081983 O60504 217 S Phosphorylation HPRD 9.0 18691976 O60504 268 S Phosphorylation HPRD 9.0 20068231 O60504 348 S Phosphorylation HPRD 9.0 17081983,20068231 O60504 366 S Phosphorylation HPRD 9.0 17081983 O60504 373 S Phosphorylation HPRD 9.0 19651622,20068231 O60504 395 S Phosphorylation HPRD 9.0 18669648,18691976,19664994,20068231 O60504 530 S Phosphorylation HPRD 9.0 15302935,18669648,19413330,19415658,18691976,19664995,16964243,18767875,18452278,20068231 O60504 544 S Phosphorylation HPRD 9.0 17322306,18669648,18767875,20068231 O60504 545 S Phosphorylation HPRD 9.0 17322306,18669648,18691976,19651622,18767875,20068231 O60504 547 S Phosphorylation HPRD 9.0 17081983,18669648 O60504 551 S Phosphorylation HPRD 9.0 17081983 O60504 563 S Phosphorylation HPRD 9.0 15302935 O60504 563 S Phosphorylation HPRD 9.0 17322306 O60504 605 S Phosphorylation HPRD 9.0 17081983,20068231 O60504 606 S Phosphorylation HPRD 9.0 17081983,18669648,20068231 O60504 610 S Phosphorylation HPRD 9.0 20068231 O60504 218 T Phosphorylation HPRD 9.0 18691976 O60504 529 T Phosphorylation HPRD 9.0 17081983,18669648,19415658,18691976,19664995,18767875,20068231 O60504 562 T Phosphorylation HPRD 9.0 17322306 O60504 585 T Phosphorylation HPRD 9.0 20068231 O60504 604 T Phosphorylation HPRD 9.0 17081983,20068231 O60504 609 T Phosphorylation HPRD 9.0 20068231 O60504 615 T Phosphorylation HPRD 9.0 18669648,20068231 O60504 217 S Phosphorylation SysPTM 1.1 18691976 O60504 395 S Phosphorylation SysPTM 1.1 18669648;18691976 O60504 530 S Phosphorylation SysPTM 1.1 15302935;18669648;16964243;18691976 O60504 545 S Phosphorylation SysPTM 1.1 18669648;17081983;18691976 O60504 547 S Phosphorylation SysPTM 1.1 17081983 O60504 551 S Phosphorylation SysPTM 1.1 18669648 O60504 563 S Phosphorylation SysPTM 1.1 15302935;17081983;18669648;18691976 O60504 218 T Phosphorylation SysPTM 1.1 18691976 O60504 529 T Phosphorylation SysPTM 1.1 16964243 O60504 562 T Phosphorylation SysPTM 1.1 17081983

PTM - HPRD Symbol Position Code Type References SORBS3 187 T Phosphorylation 17081983,18669648,19415658,18691976,19664995,18767875,20068231 SORBS3 188 S Phosphorylation 15302935,18669648,19413330,19415658,18691976,19664995,16964243,18767875,18452278,20068231 SORBS3 202 S Phosphorylation 17322306,18669648,18767875,20068231 SORBS3 203 S Phosphorylation 17322306,18669648,18691976,19651622,18767875,20068231 SORBS3 205 S Phosphorylation 18669648 SORBS3 209 S Phosphorylation 17081983 SORBS3 217 S Phosphorylation 18691976 SORBS3 218 T Phosphorylation 18691976 SORBS3 221 S Phosphorylation 15302935 SORBS3 24 S Phosphorylation 17081983 SORBS3 243 T Phosphorylation 20068231 SORBS3 262 T Phosphorylation 17081983,20068231 SORBS3 263 S Phosphorylation 17081983,20068231 SORBS3 264 S Phosphorylation 17081983,18669648,20068231 SORBS3 267 T Phosphorylation 20068231 SORBS3 268 S Phosphorylation 20068231 SORBS3 273 T Phosphorylation 18669648,20068231 SORBS3 31 S Phosphorylation 19651622,20068231 SORBS3 348 S Phosphorylation 17081983,20068231 SORBS3 366 S Phosphorylation 17081983 SORBS3 373 S Phosphorylation 19651622,20068231 SORBS3 395 S Phosphorylation 18669648,18691976,19664994,20068231 SORBS3 529 T Phosphorylation 17081983,18669648,19415658,18691976,19664995,18767875,20068231 SORBS3 53 S Phosphorylation 18669648,18691976,19664994,20068231 SORBS3 530 S Phosphorylation 15302935,18669648,19413330,19415658,18691976,19664995,16964243,18767875,18452278,20068231 SORBS3 544 S Phosphorylation 17322306,18669648,18767875,20068231 SORBS3 545 S Phosphorylation 17322306,18669648,18691976,19651622,18767875,20068231 SORBS3 547 S Phosphorylation 17081983,18669648 SORBS3 551 S Phosphorylation 17081983 SORBS3 562 T Phosphorylation 17322306 SORBS3 563 S Phosphorylation 15302935 SORBS3 563 S Phosphorylation 17322306 SORBS3 585 T Phosphorylation 20068231 SORBS3 6 S Phosphorylation 17081983,20068231 SORBS3 604 T Phosphorylation 17081983,20068231 SORBS3 605 S Phosphorylation 17081983,20068231 SORBS3 606 S Phosphorylation 17081983,18669648,20068231 SORBS3 609 T Phosphorylation 20068231 SORBS3 610 S Phosphorylation 20068231 SORBS3 615 T Phosphorylation 18669648,20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type O60504 615 T 18669648 HTP Phosphorylation O60504 529 T 18669648 HTP Phosphorylation O60504 395 S 18669648 HTP Phosphorylation O60504 530 S 18669648 HTP Phosphorylation O60504 530 S 16964243 HTP Phosphorylation O60504 530 S 17081983 HTP Phosphorylation O60504 544 S 18669648 HTP Phosphorylation O60504 551 S 18669648 HTP Phosphorylation O60504 556 T 18669648 HTP Phosphorylation O60504 547 S 18669648 HTP Phosphorylation O60504 545 S 18669648 HTP Phosphorylation O60504 545 S 17081983 HTP Phosphorylation O60504 348 S 17081983 HTP Phosphorylation O60504 563 S 18669648 HTP Phosphorylation O60504 563 S 18220336 HTP Phosphorylation O60504 562 T 18669648 HTP Phosphorylation O60504 606 S 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs O60504 348 Phosphoserine 23186163;24275569 O60504 395 Phosphoserine 20068231;23186163 O60504 530 Phosphoserine; by MAPK1 16964243;18669648;19690332;20068231;23186163;24275569 O60504 544 Phosphoserine 21406692;23186163 O60504 545 Phosphoserine 20068231;21406692;23186163 O60504 547 Phosphoserine 24275569 O60504 551 Phosphoserine 18669648;20068231;24275569 O60504 563 Phosphoserine 18669648;19690332;20068231;21406692;23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type SORBS3 IPI00419847 S 217 YRPGAFpSTVLQPS phosphorylation SORBS3 IPI00419847 S 348 KMADGGpSPFLGRR phosphorylation SORBS3 IPI00419847 S 373 ASNGGGpSPARREE phosphorylation SORBS3 IPI00419847 S 395 FDFQAQpSPKELTL phosphorylation SORBS3 IPI00419847 S 530 GPQLPTpSPRLTAA phosphorylation SORBS3 IPI00419847 S 544 RSARHPpSSPSALR phosphorylation SORBS3 IPI00419847 S 545 SARHPSpSPSALRS phosphorylation SORBS3 IPI00419847 S 551 SPSALRpSPADPTD phosphorylation SORBS3 IPI00419847 S 563 DLGGQTpSPRRTGF phosphorylation SORBS3 IPI00419847 S 606 LDLGTSpSPNTSQI phosphorylation SORBS3 IPI00419847 S 610 TSSPNTpSQIHWTP phosphorylation SORBS3 IPI00419847 T 218 RPGAFSpTVLQPSN phosphorylation SORBS3 IPI00419847 T 529 DGPQLPpTSPRLTA phosphorylation SORBS3 IPI00419847 T 562 TDLGGQpTSPRRTG phosphorylation SORBS3 IPI00419847 T 585 QTQNLGpTPGPALS phosphorylation SORBS3 IPI00419847 T 609 GTSSPNpTSQIHWT phosphorylation SORBS3 IPI00419847 T 615 TSQIHWpTPYRAMY phosphorylation