PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus BCAR3 PDLIM2 25640309 biogrid,intact exp G G G P GP G G GP G GP G GP GP G GP GP G P G GP G G GP GP G GP GP G APC PDLIM2 25640309 biogrid,intact exp G G G G GP GP G G GP G GP G GP GP G GP GP G GP G P G G GP GP GP GP GP RAF1 PDLIM2 25640309 biogrid,intact exp G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP GP GP GP G FGFR4 PDLIM2 25640309 biogrid,intact exp G P P GP GP G GP GP GP P G GP P GP GP GP GP P ACD PDLIM2 21044950 biogrid,intact exp G G G G G GP G G GP G GP G GP GP G GP GP G GP G P G G GP GP GP GP GP G PDLIM2 UBE2E2 15963787 biogrid exp G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP GP GP GP G TGFB1 PDLIM2 25640309 biogrid,intact exp G G G G GP G G G G G G G G G G GP G G G G GP G G GP GP GP G G FGFR2 PDLIM2 25640309 biogrid,intact exp G G G P GP GP G GP G GP P G GP GP G GP G GP G G P GP P GP GP G PDLIM2 POT1 21044950 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G AURKA PDLIM2 25640309 biogrid,intact exp G GP P G G G G GP G P G P G G G G GP BAG4 PDLIM2 25640309 biogrid,intact exp G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP GP GP GP G PDLIM2 PDLIM2 15963787 biogrid exp, ortho G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP GP GP GP G STAT4 PDLIM2 15963787, 25402006 biogrid exp, ortho, pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G G GP GP GP GP G MYH9 PDLIM2 ortho G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP G GP GP G PRKCA PDLIM2 ortho G G G G GP GP G G GP G GP G G GP G GP GP G GP G GP G G GP GP G GP GP G YWHAH PDLIM2 ortho G G G G GP GP G G GP G GP G GP G G GP GP G GP G GP G G GP GP GP GP GP G YWHAE PDLIM2 ortho G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP GP GP GP G STAT1 PDLIM2 ortho G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G G GP GP G GP G UBE2D1 PDLIM2 ortho G G G G GP GP G G GP G GP G GP GP G G GP G GP G GP G G GP G GP GP GP G FLNA PDLIM2 21836163 ortho, pred G G G G GP GP G G GP G GP G GP GP G G GP G GP G GP G G G G G GP GP G ACTN4 PDLIM2 25402006, 21836163 ortho, pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP GP GP GP G ACTN1 PDLIM2 21836163 ortho, pred G G G G GP GP G G G G G G GP GP G G GP G G G GP G G GP G GP G G G PARD3 PDLIM2 23023127 pred G G G G GP GP G G GP G GP G GP G G GP GP G GP G GP G G G GP GP GP GP G PDLIM2 RAPGEF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PTPN13 PDLIM2 23023127 pred G G G P GP G G GP G GP GP GP G GP GP G GP G P G G GP GP GP GP G CAPZA2 PDLIM2 21836163 pred G G G G GP GP G G GP G G G GP GP G GP GP G GP G GP G G G GP GP GP GP G LNX1 PDLIM2 23023127 pred G G G GP G G GP G GP G GP GP G GP GP G GP G GP G G G GP P GP GP PDLIM2 TJP2 23023127 pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP G GP GP G PDLIM2 ANKRD2 21836163 pred G GP GP G PDLIM2 PDZRN3 23023127 pred G G G GP G G GP G GP GP GP G GP GP G P GP G G GP GP P GP GP G INADL PDLIM2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G PDLIM2 DFNB31 23023127 pred G G G GP G G GP G GP P GP G GP GP G P G P G G P GP G GP GP G TJP3 PDLIM2 23023127 pred P GP GP G GP G GP P P GP G GP GP GP PDLIM2 MAGI1 23023127 pred G G G G G G G G GP G GP G GP G G GP G G GP G G G G G GP G GP G G PARD3B PDLIM2 23023127 pred G G G GP G G GP G GP G GP G G GP GP G GP G GP G G GP GP G GP G G PDLIM1 PDLIM2 21836163 pred G G G G GP GP G G GP G GP G GP GP G GP GP G G G GP G G G GP GP GP GP G NEB PDLIM2 21836163 pred G P G G G G P G G G G G GP G P G PDZK1P1, PDZK1P2 PDLIM2 23023127 pred DLG4 PDLIM2 23023127 pred G GP G G G G GP G G G G G G G G LNX2 PDLIM2 23023127 pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP GP GP GP G PDLIM5 PDLIM2 23023127 pred G G P P G G GP GP G GP GP G GP P G P G GP G G GP GP GP GP P G RGS3 PDLIM2 23023127 pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP GP GP GP G PDLIM2 MAGIX 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G MLLT4 PDLIM2 23023127 pred G G G G GP GP G G GP G GP G GP G G GP GP G GP G GP G G GP GP G GP GP G DLG3 PDLIM2 23023127 pred G G G G G GP G G G G GP G G G G G GP G G G GP G G G G G GP GP G RADIL PDLIM2 23023127 pred G G G GP G G GP G P G GP G GP GP G GP G P G G GP GP GP G PALLD PDLIM2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DLG5 PDLIM2 23023127 pred G G G GP G G G G G G G G G G GP G G G G G G G G G G G G PDLIM2 MYOT 21836163 pred G G G G G G G G GP G G GRASP PDLIM2 23023127 pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G GP GP GP GP GP G MPDZ PDLIM2 23023127 pred G G G P GP G G GP G GP G GP GP G GP GP G P G GP G G GP GP G GP GP G CSRP3 PDLIM2 21836163 pred G GP G P MAGI2 PDLIM2 23023127 pred G G G P GP G G GP G GP G GP G G G GP G GP G P G G GP G GP G GP G FBP2 PDLIM2 21836163 pred P P P P P P P P P P GP GP P P P SYNJ2BP PDLIM2 23023127 pred G G G G G GP G G GP G GP G GP G G GP GP G GP G GP G G G GP G GP GP G PDLIM2 PPP1R9A 23023127 pred G G G P GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP GP GP GP G PDLIM2 PDZD7 23023127 pred G G G G G G G G G G G G G G G G G G G SLC9A3R2 PDLIM2 23023127 pred P P G GP GP G G GP P P G GP GP PDZD8 PDLIM2 23023127 pred G G G G G GP G G GP G GP G GP G G GP GP G GP G GP G G G GP GP GP GP G OBSL1 PDLIM2 21836163 pred G G G GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP GP GP GP G PDLIM2 SHANK1 23023127 pred G P P P P P P P P GP P P P P P LDB3 PDLIM2 21836163 pred G G G G G G G G GP G G G G G G G GP G G GP G G GP G FRMPD2 PDLIM2 23023127 pred P P P P P P P P P PDLIM2 MYOZ2 21836163 pred G G GP G PDZD11 PDLIM2 23023127 pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP GP GP GP G PTPN4 PDLIM2 23023127 pred G G G G G GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP G GP GP G SCRIB PDLIM2 23023127 pred G G G G G G G G GP G GP G GP G G GP G G GP G GP G G G GP G GP GP G PDLIM4 PDLIM2 23023127 pred G G G P GP G G GP G GP GP G G GP GP G GP G G G G G GP GP GP G G TCAP PDLIM2 21836163 pred G G G G GP G G PDLIM2 LRRC7 23023127 pred G P GP P G P P P P GP P P P P P P P PDLIM2 GRIP2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAST4 PDLIM2 23023127 pred G G G G G GP G G G G G G G G G GP GP G GP G GP G G G GP G GP GP G PDZD2 PDLIM2 23023127 pred G G G GP G G G G GP GP G GP GP G G G G G GP GP GP GP G ARHGEF11 PDLIM2 23023127 pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP GP GP GP G PDLIM2 GOPC 23023127 pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP GP GP GP G SHROOM3 PDLIM2 23023127 pred G G GP G G GP G GP G GP G GP GP GP G G G G GP G GP P G FRMPD2B PDLIM2 23023127 pred PDLIM2 MYO6 21836163 pred G G G GP G G GP G GP G GP G G GP GP G GP G GP G G P GP G GP GP NEBL PDLIM2 21836163 pred G G G G G G G G GP G GP G GP GP G GP G G GP G G G G G GP P GP G G PDLIM2 GRIP1 23023127 pred G P GP G GP G GP P P G P GP P G GP G G P P GP GP P STK35 PDLIM2 21836163 pred G G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP G GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q96JY6 Q04206 affinity chromatography technology 17468759 physical association X 2 Q9NUX5-2 Q96JY6 two hybrid 21044950 direct interaction X 2 Q96AP0-2 Q96JY6 two hybrid 21044950 direct interaction X 2 P0CG48 Q96JY6 affinity chromatography technology 21139048 physical association X 2 P21802 Q96JY6 two hybrid array 25640309 physical association X 2 O14965 Q96JY6 two hybrid array 25640309 physical association X 2 O95429 Q96JY6 two hybrid array 25640309 physical association X 2 P25054 Q96JY6 two hybrid array 25640309 physical association X 2 O75815 Q96JY6 two hybrid array 25640309 physical association X 2 P22455 Q96JY6 two hybrid array 25640309 physical association X 2 L7RRS6 Q96JY6 two hybrid array 25640309 physical association X 2 P01137 Q96JY6 two hybrid array 25640309 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B RELA PDLIM2 MI:0004(affinity chromatography technology) 17468759 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_121721 prey bait ACD PDLIM2 MI:0018(two hybrid) 21044950 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_198477 bait prey PDLIM2 POT1 MI:0018(two hybrid) 21044950 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_198594 prey bait UBC PDLIM2 MI:0004(affinity chromatography technology) 21139048 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_167877 bait prey

PPI - HINT Gene A Gene B PMID Method Quality AURKA PDLIM2 25640309,25640309 0018,0397 HT BCAR3 PDLIM2 25640309,25640309 0018,0397 HT BAG4 PDLIM2 25640309,25640309 0018,0397 HT TGFB1 PDLIM2 25640309,25640309 0018,0397 HT RAF1 PDLIM2 25640309,25640309 0018,0397 HT FGFR2 PDLIM2 25640309,25640309 0018,0397 HT FGFR4 PDLIM2 25640309,25640309 0018,0397 HT APC PDLIM2 25640309,25640309 0018,0397 HT ACD PDLIM2 21044950,21044950,21044950 0809,0018,0096 HT PDLIM2 PDLIM2 15963787 0415 LC PDLIM2 POT1 21044950,21044950 0809,0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9NUX5 Q96JY6 POT1 PDLIM2 0.183 21044950 Q96JY6 Q96AP0 PDLIM2 ACD 0.183 21044950 Q96JY6 O14965 PDLIM2 AURKA 0.286 25640309 Q96JY6 O75815 PDLIM2 BCAR3 0.286 25640309 Q96JY6 O95429 PDLIM2 BAG4 0.286 25640309 Q96JY6 P01137 PDLIM2 TGFB1 0.126 25640309 Q96JY6 P04049 PDLIM2 RAF1 0.126 25640309 Q96JY6 P21802 PDLIM2 FGFR2 0.126 25640309 Q96JY6 P22455 PDLIM2 FGFR4 0.126 25640309 Q96JY6 P25054 PDLIM2 APC 0.286 25640309 Q96JY6 Q14765 PDLIM2 STAT4 0.21 15963787 Q96JY6 Q96JY6 PDLIM2 PDLIM2 0.332 15963787 Q96LR5 Q96JY6 UBE2E2 PDLIM2 0.309 15963787

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 AURKA PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database ACTN4 PDLIM2 MI:0362 inference MI:0461 interaction database FLNB PDLIM2 MI:0362 inference MI:0461 interaction database BCAR3 PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database BAG4 PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database MYC PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database TGFB1 PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database RAF1 PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database UBC PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database ACTN1 PDLIM2 MI:0362 inference MI:0461 interaction database PRKCA PDLIM2 MI:0362 inference MI:0461 interaction database FLNA PDLIM2 MI:0362 inference MI:0461 interaction database TAF1 PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database FGFR2 PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database FGFR4 PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database APC PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database MYH9 PDLIM2 MI:0362 inference MI:0461 interaction database ACTN2 PDLIM2 MI:0362 inference MI:0461 interaction database STAT1 PDLIM2 MI:0362 inference MI:0461 interaction database UBE2D1 PDLIM2 MI:0362 inference MI:0461 interaction database UBE2E1 PDLIM2 MI:0362 inference MI:0461 interaction database YWHAG PDLIM2 MI:0362 inference MI:0461 interaction database UBE2D2 PDLIM2 MI:0362 inference MI:0461 interaction database RELA PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database YWHAH PDLIM2 MI:0362 inference MI:0461 interaction database STAT4 PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 PDLIM2 MI:0362 inference MI:0461 interaction database ACD PDLIM2 MI:0045 experimental interaction detection MI:0461 interaction database PDLIM2 UBE2E2 MI:0045 experimental interaction detection MI:0461 interaction database PDLIM2 POT1 MI:0045 experimental interaction detection MI:0461 interaction database PDLIM2 MYO6 MI:0362 inference MI:0461 interaction database