PTM - CPLM Gene Name UniProt ID Type Position Code RNF2; BAP1; DING; HIPI3; RING1B Q99496 Acetylation 249 K RNF2; BAP1; DING; HIPI3; RING1B Q99496 Ubiquitination 149 K RNF2; BAP1; DING; HIPI3; RING1B Q99496 Ubiquitination 249 K RNF2; BAP1; DING; HIPI3; RING1B Q99496 Ubiquitination 261 K RNF2; BAP1; DING; HIPI3; RING1B Q99496 Ubiquitination 320 K RNF2; BAP1; DING; HIPI3; RING1B Q99496 Ubiquitination 323 K

PTM - dbPAF Gene Name UniProt ID Position Type Species RNF2; BAP1; DING; HIPI3; RING1B Q99496 116 S Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 120 Y Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 143 S Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 168 S Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 176 S Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 183 S Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 186 S Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 199 T Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 2 S Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 200 S Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 203 S Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 247 Y Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 260 S Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 262 Y Homo sapiens(Human) RNF2; BAP1; DING; HIPI3; RING1B Q99496 41 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q99496 K249-ac Acetylation SAQTRyIkTSGNATV Q99496 S2-p Phosphorylation ______MsQAVQTNG Q99496 S41-p Phosphorylation DGLEIVVsPRSLHSE Q99496 S99-p Phosphorylation KKLVSKRsLRPDPNF Q99496 S116-p Phosphorylation LISKIYPsRDEyEAH Q99496 Y120-p Phosphorylation IYPsRDEyEAHQERV Q99496 S143-p Phosphorylation NQQALSHsIEEGLkI Q99496 S168-p Phosphorylation KQQIENGsGAEDNGD Q99496 S200-p Phosphorylation SNKRTKTsDDSGLEL Q99496 Y247-p Phosphorylation DDSAQTRyIkTSGNA Q99496 S260-p Phosphorylation NATVDHLskyLAVRL Q99496 Y262-p Phosphorylation TVDHLskyLAVRLAL Q99496 K323-sm Sumoylation EKYWKVNkPMELYYA Q99496 K65-ub Ubiquitination LKNTMTTkECLHRFC Q99496 K149-ub Ubiquitination HsIEEGLkIQAMNRL Q99496 K249-ub Ubiquitination SAQTRyIkTSGNATV Q99496 K261-ub Ubiquitination ATVDHLskyLAVRLA Q99496 K323-ub Ubiquitination EKYWKVNkPMELYYA

PTM - dbPTM UniProt ID Position Code Type Resources References Q99496 168 S Phosphorylation Swiss-Prot 1010711 17081983;19413330 Q99496 203 S Phosphorylation Swiss-Prot 1010711 19007248 Q99496 149 K Ubiquitylation Phosphositeplus.1010730 21890473 Q99496 249 K Ubiquitylation Phosphositeplus.1010730 21890473 Q99496 261 K Ubiquitylation Phosphositeplus.1010730 21890473 Q99496 323 K Ubiquitylation Phosphositeplus.1010730 21890473 Q99496 249 K Acetylation Phosphositeplus.1010730 20167786 Q99496 143 S Phosphorylation Phosphositeplus.1010730 20068231;21406692 Q99496 2 S Phosphorylation Phosphositeplus.1010730 19405034;19691289 Q99496 41 S Phosphorylation Phosphositeplus.1010730 19405034;21659604 Q99496 2 S Acetylation HPRD 9.0 19413330 Q99496 2 S Phosphorylation HPRD 9.0 19007248,19691289 Q99496 143 S Phosphorylation HPRD 9.0 20068231 Q99496 168 S Phosphorylation HPRD 9.0 17081983,19413330 Q99496 203 S Phosphorylation HPRD 9.0 19007248 Q99496 168 S Phosphorylation SysPTM 1.1 17081983

PTM - HPRD Symbol Position Code Type References RNF2 143 S Phosphorylation 20068231 RNF2 168 S Phosphorylation 17081983,19413330 RNF2 2 S Acetylation 19413330 RNF2 2 S Phosphorylation 19007248,19691289 RNF2 203 S Phosphorylation 19007248

PTM - UniProt UniProt ID Position Type PMIDs Q99496 2 N-acetylserine 19413330 Q99496 143 Phosphoserine 23186163 Q99496 168 Phosphoserine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type RNF2 IPI00026993 S 143 QQALSHpSIEEGLK phosphorylation RNF2 IPI00026993 S 168 QQIENGpSGAEDNG phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 6045 111972 - K Ubiquitination 17157253 6045 111972 - K Ubiquitination 20800574 6045 111972 - K Ubiquitination 21139048 6045 111972 - K Ubiquitination 21890473 6045 111972 - K Ubiquitination 22910419 6045 111972 - K FAT10ylation 22797925 6045 111972 - K Ubiquitination 23000965 6045 111972 - K Ubiquitination 23671107 6045 111972 - K Ubiquitination 24634510 6045 111972 - K Neddylation 24634510

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID BAP1 Homo sapiens (Human) 139; 630 "139,NAPELAKAHNSHA; 630,GEKYSPKELLALL" 139:21890473; 630:21890473 RNF2 Homo sapiens (Human) 251; 248; 189; 177 "251,KYWKVNKPMELYY; 248,VSEKYWKVNKPME; 189,TVDHLSKYLAVRL; 177,AQTRYIKTSGNAT" 251:21890473; 248:21890473; 189:21890473; 177:21890473 RNF2 Homo sapiens (Human) 323; 320; 249; 261; 149 "323,KYWKVNKPMELYY; 320,VSEKYWKVNKPME; 249,AQTRYIKTSGNAT; 261,TVDHLSKYLAVRL; 149,SIEEGLKIQAMNR" 323:21890473; 320:21890473; 249:21890473; 261:21890473; 149:21890473 BAP1 Homo sapiens (Human) 60 "60,NAPELAKAHNSHA" 60:21890473 BAP1 Homo sapiens (Human) 139; 630 "139,NAPELAKAHNSHA; 630,GEKYSPKELLALL" 139:21890473; 630:21890473