PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus KLHL7 KLHL7 21828050 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G KLHL7 AXIN2 19888210 i2d exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G NUP153 KLHL7 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G CUL3 KLHL7 21828050,21145461 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G NR2C2 KLHL7 26496610 biogrid,intact exp G GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP G GP GP G KLHL7 NXF1 22658674 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G RBX1 KLHL7 21828050 biogrid,intact exp G G G G G GP G GP G G G G GP G G G GP G GP G GP GP G G G G G GP G KLHL7 NUP50 26186194 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G UBC KLHL7 21828050 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G KLHL7 BOD1L1 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G KLHL7 MOV10 22658674 biogrid exp G G G G G G G G G G G G G G G G G G G G G G CKAP5 KLHL7 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G FERMT3 KLHL7 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G YWHAZ KLHL7 26496610 biogrid,intact exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G KLHL7 C9orf41 26186194 biogrid exp GP GP G G G GP GP GP GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP BCL6 KLHL7 23023127 pred G G G G G G G G G G G G G GP G G G G G G GP G G G G G G G G KLHL7 RP9 23023127 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP G G GP GP GP GP GP G GP GP G KLHL7 KLHL25 23023127 pred GP GP G G G GP G P GP G GP GP GP GP G GP GP G GP G P GP GP GP GP G GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8IXQ5 anti tag coimmunoprecipitation 21828050 association C 3 Q8IXQ5 anti tag coimmunoprecipitation 21828050 association C 3 Q8IXQ5 anti tag coimmunoprecipitation 21828050 association C 3 Q8IXQ5 anti tag coimmunoprecipitation 21828050 association C 3 Q8IXQ5 anti tag coimmunoprecipitation 21828050 association C 3 Q8IXQ5 anti tag coimmunoprecipitation 21828050 association C 3 Q8IXQ5 anti tag coimmunoprecipitation 21828050 association C 3 Q8IXQ5 A0A024R475 fluorescence microscopy 21828050 colocalization X 2 Q8IXQ5 A0A024R475 fluorescence microscopy 21828050 colocalization X 2 Q8IXQ5 A0A024R475 anti tag coimmunoprecipitation 21828050 physical association X 2 Q8IXQ5 tandem affinity purification 22810585 association C 37 Q8IXQ5 Q8IXQ5 anti tag coimmunoprecipitation 21828050 physical association X 2 Q8IXQ5 Q8IXQ5 anti tag coimmunoprecipitation 21828050 physical association X 2 Q8IXQ5 Q8IXQ5 anti tag coimmunoprecipitation 21828050 physical association X 2 Q8IXQ5 Q8IXQ5 fluorescence microscopy 21828050 colocalization X 2

PPI - HINT Gene A Gene B PMID Method Quality NR2C2 KLHL7 26496610,26496610 0007,0004 HT NUP153 KLHL7 26496610,26496610 0007,0004 HT YWHAZ KLHL7 26496610,26496610 0007,0004 HT CUL3 KLHL7 21828050,21145461,21828050,21828050 0004,0004,0007,0416 LC,HT CKAP5 KLHL7 26496610,26496610 0007,0004 HT FERMT3 KLHL7 26496610,26496610 0007,0004 HT KLHL7 CARNMT1 26186194 0004 HT KLHL7 BOD1L1 26496610,26496610 0007,0004 HT KLHL7 NUP50 26186194 0004 HT NR2C2 KLHL7 26496610,26496610 0007,0004 HT NUP153 KLHL7 26496610,26496610 0007,0004 HT YWHAZ KLHL7 26496610,26496610 0007,0004 HT CUL3 KLHL7 21145461 0004 HT CKAP5 KLHL7 26496610,26496610 0007,0004 HT FERMT3 KLHL7 26496610,26496610 0007,0004 HT KLHL7 CARNMT1 26186194 0004 HT KLHL7 BOD1L1 26496610,26496610 0007,0004 HT KLHL7 NUP50 26186194 0004 HT CUL3 KLHL7 21828050,21828050,21828050 0004,0007,0416 LC UBC KLHL7 21828050 0415 LC CUL3 KLHL7 21828050,21828050,21828050 0004,0007,0416 LC KLHL7 KLHL7 21828050,21828050,21828050 0004,0007,0416 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8IXQ5 Q05322 KLHL7 VP24 0.126 22810585 Q8N4J0 Q8IXQ5 C9ORF41 KLHL7 0.126 26186194 Q9HCE1 Q8IXQ5 MOV10 KLHL7 0.126 22658674 Q8IXQ5 Q8IXQ5 KLHL7 KLHL7 0.236 21828050 Q8IXQ5 P0CG48 KLHL7 UBC 0.309 21828050 Q8IXQ5 P62877 KLHL7 RBX1 0.21 21828050 Q9C0F1 Q8IXQ5 CEP44 KLHL7 0.126 unassigned1312 Q8NFC6 Q8IXQ5 BOD1L1 KLHL7 0.126 26496610 Q8IXQ5 P10071 KLHL7 GLI3 0.126 unassigned1312 Q8IXQ5 Q86UX7 KLHL7 FERMT3 0.126 26496610 Q9JK83 Q8IXQ5 PARD6B KLHL7 0.236 26496610 Q9JLV5 Q8IXQ5 CUL3 KLHL7 0.236 26496610 Q9Z179 Q8IXQ5 SHCBP1 KLHL7 0.236 26496610 Q8IXQ5 P09803 KLHL7 CDH1 0.236 26496610 Q924S7 Q8IXQ5 SPRED2 KLHL7 0.236 26496610 Q8IXQ5 Q3UDE2 KLHL7 TTLL12 0.236 26496610 Q8IXQ5 Q8BGH2 KLHL7 SAMM50 0.236 26496610 Q8IXQ5 Q8BM85 KLHL7 TBCK 0.236 26496610 Q8IXQ5 Q8CCJ3 KLHL7 UFL1 {ECO:0000312|MGI:MGI:1914740} 0.236 26496610 Q9UBU9 Q8IXQ5 NXF1 KLHL7 0.126 22658674 Q9UKX7 Q8IXQ5 NUP50 KLHL7 0.126 26186194 Q8IXQ5 Q13618 KLHL7 CUL3 0.309 21828050,21145461 Q8IXQ5 Q14008 KLHL7 CKAP5 0.126 26496610 Q8IXQ5 P49116 KLHL7 NR2C2 0.126 26496610 Q8IXQ5 P49790 KLHL7 NUP153 0.126 26496610 Q8IXQ5 P63104 KLHL7 YWHAZ 0.126 26496610

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 UFL1 KLHL7 MI:0362 inference MI:0461 interaction database UBC KLHL7 MI:0045 experimental interaction detection MI:0461 interaction database CDH1 KLHL7 MI:0362 inference MI:0461 interaction database NR2C2 KLHL7 MI:0045 experimental interaction detection MI:0461 interaction database NUP153 KLHL7 MI:0045 experimental interaction detection MI:0461 interaction database RBX1 KLHL7 MI:0045 experimental interaction detection MI:0461 interaction database YWHAZ KLHL7 MI:0045 experimental interaction detection MI:0461 interaction database CUL3 KLHL7 MI:0045 experimental interaction detection MI:0461 interaction database CKAP5 KLHL7 MI:0045 experimental interaction detection MI:0461 interaction database TTLL12 KLHL7 MI:0362 inference MI:0461 interaction database SPRED2 KLHL7 MI:0362 inference MI:0461 interaction database FERMT3 KLHL7 MI:0045 experimental interaction detection MI:0461 interaction database KLHL7 CARNMT1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL7 SHCBP1 MI:0362 inference MI:0461 interaction database KLHL7 BOD1L1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL7 TBCK MI:0362 inference MI:0461 interaction database KLHL7 PARD6G MI:0362 inference MI:0461 interaction database KLHL7 PARD6B MI:0362 inference MI:0461 interaction database KLHL7 MOV10 MI:0045 experimental interaction detection MI:0461 interaction database KLHL7 PARD6A MI:0362 inference MI:0461 interaction database KLHL7 NXF1 MI:0045 experimental interaction detection MI:0461 interaction database KLHL7 NUP50 MI:0045 experimental interaction detection MI:0461 interaction database KLHL7 SAMM50 MI:0362 inference MI:0461 interaction database