PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus DCAF10 AGO1 24778252 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DCAF10 PPP2R2C 26186194 biogrid exp G G G G GP G G G G G GP G G G P G P G G TRUB2 DCAF10 26186194 biogrid exp G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G TCEA2 DCAF10 16169070 hprd,i2d,intact exp G G G GP G GP G G G G GP G G G GP G G G G G GP G G GP G G DCAF10 JRKL 26496610 biogrid,intact exp G G G G G GP G G G G G G GP G G G GP G G G G G G G G G GP G G GNAZ DCAF10 26186194 biogrid exp G G G G G GP G GP G G G G G G G G GP G G G G G G G G G GP G G DCAF10 SNX11 26186194 biogrid exp G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G SRPK2 DCAF10 26167880 biogrid exp G G G G G GP G G G G G G G G G G GP G G G G G G GP G G G G G DIRAS3 DCAF10 26186194 biogrid exp G G GP GP G G P G GP G G G G P G GP DCAF10 COPS7A 26496610 biogrid,intact exp G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 COPS6 19295130 biogrid exp G G G G G GP G GP G G G G GP G G G GP G G G G G G G G G GP G G EIF3I DCAF10 26186194 biogrid exp G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 SCRN2 26186194 biogrid exp G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 ACTR8 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DCAF10 SLX4 19596235 biogrid,intact exp G G G GP P G P G G G GP G G P G DCAF10 HDAC7 26186194 biogrid exp G G G G G GP G GP G G G G G G G G GP G G G G G G G G G GP G G DCAF10 DDA1 19295130, 25402006 biogrid exp, pred G G G G G GP G GP G G G G GP G G GP G G G G G GP G G GP G G DDB1 DCAF10 16949367,16964240, 25402006, 23023127 biogrid exp, pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G CUL4A DCAF10 21145461,16964240, 25402006 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CUL4B DCAF10 26496610, 25402006 biogrid,intact exp, pred G G G G G GP G GP G G G G G G G G GP G G G G G G GP G G GP G G DCAF10 WDTC1 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 DTL 25402006 pred G G P G P G P G P G G G G DCAF10 DDB2 25402006 pred G G G G G GP G G G G G G GP G G G GP G G G G G G G G GP G G UBXN7 DCAF10 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G CDC20 DCAF10 23023127 pred G G G G G G G G GP G DCAF10 DCAF8 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 DCAF11 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DCAF7 DCAF10 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G UBXN1 DCAF10 25402006 pred G G G G G GP G G G G G G GP G G G GP G G G G G G GP G G GP G G DCAF6 DCAF10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAP3K1 DCAF10 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 DCAF16 25402006 pred G G G G G GP G G G G G G G G G G GP G G G G G G G G G GP G G DCAF10 TRAF7 23023127 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 DCAF4 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G G G G GP G G DCAF10 RFWD2 25402006 pred G G G G G GP G G G G G G G G G G GP G G G G G G G G G GP G G RBX1 DCAF10 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G G G G G G G ERCC8 DCAF10 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DCAF10 DCAF13 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 DDIT4 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G TLE2 DCAF10 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 DCAF12 25402006 pred G G G G G GP G G G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 MAP3K3 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G G G G GP G G DCAF10 VPRBP 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G G G G GP G G DCAF10 AMBRA1 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G GP G G GP G G DCAF17 DCAF10 25402006 pred G GP G G G G G GP G G G G G GP G DCAF10 COPS5 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 PHIP 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 DCAF5 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G G G G GP G G DCAF10 TRPC4AP 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G G G G GP G G DCAF10 COPS7B 25402006 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 RFWD3 23023127 pred G G G G G G G G G G G G G G G G G G ARNT DCAF10 23023127 pred G G G G G GP G G G G G G GP G G G GP G G G G G G GP G G GP G G DCAF10 DET1 25402006 pred G G G G G GP G G G G G G GP G G G GP G G G G G G GP G G GP G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q5QP82 B2RBV7 affinity chromatography technology 21145461 physical association X 2 Q5QP82 Q7L5N1 affinity chromatography technology 19295130 physical association X 2 Q5QP82 P0CG48 affinity chromatography technology 22505724 physical association X 2 Q5QP82 P0CG48 affinity chromatography technology 21963094 physical association X 2 Q5QP82 P0CG48 affinity chromatography technology 23000965 physical association X 2 Q5QP82 P0CG48 affinity chromatography technology 25147182 physical association X 2 Q5QP82 Q16531 affinity chromatography technology 16964240 physical association X 2 Q5QP82 B2RBV7 affinity chromatography technology 16964240 physical association X 2 Q5QP82 Q16531 affinity chromatography technology 16949367 physical association X 2 Q5QP82 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 Q5QP82 P0CG48 affinity chromatography technology 21139048 physical association X 2 Q5QP82 P0CG48 affinity chromatography technology 21890473 physical association X 2 Q5QP82 Q9BW61 affinity chromatography technology 19295130 physical association X 2 Q5QP82 Q9UL18 affinity chromatography technology 24778252 physical association X 2 Q5QP82 Q8IY92 affinity chromatography technology 19596235 physical association X 2 Q5QP82 Q15560-2 two hybrid 16169070 - X 2 Q5QP82 Q15560-2 two hybrid 16169070 - X 2 Q5QP82 anti tag coimmunoprecipitation 19596235 association C 24 Q5QP82 tandem affinity purification 20360068 physical association C 32 Q5QP82 Q15560 two hybrid pooling approach 16169070 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B TCEA2 DCAF10 MI:0492(in vitro)|MI:0007(anti tag coimmunoprecipitation) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(intact) HPRD_30187|UniProt_156607 -|bait -|prey DCAF10 COPS6 MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221797 prey bait CUL4A DCAF10 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16964240,21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_202978|BIOGRID_122528 bait|bait prey|prey UBC DCAF10 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21139048,21890473,21963094,22505724,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_176485|BIOGRID_225146|BIOGRID_263786|BIOGRID_267441|BIOGRID_171619 bait|bait|bait|bait|bait prey|prey|prey|prey|prey DCAF10 DDA1 MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221656 prey bait DDB1 DCAF10 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16949367,16964240 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_122852|BIOGRID_122501 bait|bait prey|prey DCAF10 SLX4 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 19596235 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_120892|UniProt_100544 prey|prey bait|bait

PPI - HINT Gene A Gene B PMID Method Quality DIRAS3 DCAF10 26186194 0004 HT TRUB2 DCAF10 26186194 0004 HT GNAZ DCAF10 26186194 0004 HT CUL4A DCAF10 16964240,21145461 0004,0004 LC,HT CUL4B DCAF10 26496610,26496610 0007,0004 HT DDB1 DCAF10 16949367,16964240 0004,0004 LC DCAF10 EIF3S2 26186194 0004 HT DCAF10 HDAC7 26186194 0004 HT DCAF10 SCRN2 26186194 0004 HT DCAF10 ACTR8 26186194 0004 HT DCAF10 COPS7A 26496610,26496610 0007,0004 HT DCAF10 PPP2R2C 26186194 0004 HT DCAF10 JRKL 26496610,26496610 0007,0004 HT DCAF10 SNX11 26186194 0004 HT DIRAS3 DCAF10 26186194 0004 HT TRUB2 DCAF10 26186194 0004 HT GNAZ DCAF10 26186194 0004 HT CUL4A DCAF10 21145461 0004 HT CUL4B DCAF10 26496610,26496610 0007,0004 HT DCAF10 EIF3S2 26186194 0004 HT DCAF10 HDAC7 26186194 0004 HT DCAF10 SCRN2 26186194 0004 HT DCAF10 ACTR8 26186194 0004 HT DCAF10 COPS7A 26496610,26496610 0007,0004 HT DCAF10 PPP2R2C 26186194 0004 HT DCAF10 JRKL 26496610,26496610 0007,0004 HT DCAF10 SNX11 26186194 0004 HT CUL4A DCAF10 16964240 0004 LC DDB1 DCAF10 16949367,16964240 0004,0004 LC CCP110 DCAF10 18694559 0018 LC SRPK2 DCAF10 26167880 0415 LC TCEA2 DCAF10 16169070,16169070 0018,0398 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9H981 Q5QP82 ACTR8 DCAF10 0.126 26186194 Q9Y5W9 Q5QP82 SNX11 DCAF10 0.126 26186194 Q9Y2T4 Q5QP82 PPP2R2C DCAF10 0.126 26186194 Q7L5N1 Q5QP82 COPS6 DCAF10 0.126 19295130 Q5QP82 O95661 DCAF10 DIRAS3 0.126 26186194 Q5QP82 O95900 DCAF10 TRUB2 0.126 26186194 Q9Y4A0 Q5QP82 JRKL DCAF10 0.236 26496610 Q9UBW8 Q5QP82 COPS7A DCAF10 0.236 26496610 Q5QP82 Q13619 DCAF10 CUL4A 0.236 16964240,21145461 Q5QP82 Q13620 DCAF10 CUL4B 0.236 26496610 Q9D9Z5 Q5QP82 DDA1 DCAF10 0.236 26496610 Q5QP82 Q16531 DCAF10 DDB1 0.236 16949367,16964240 Q5QP82 Q3TCH7 DCAF10 CUL4A 0.236 26496610 Q5QP82 P62700 DCAF10 YPEL5 0.236 26496610 Q8IY92 Q5QP82 SLX4 DCAF10 0.332 19596235 Q5QP82 Q3U1J4 DCAF10 DDB1 0.416 26496610,20360068 Q8WUI4 Q5QP82 HDAC7 DCAF10 0.126 26186194 Q96FV2 Q5QP82 SCRN2 DCAF10 0.126 26186194 Q9BW61 Q5QP82 DDA1 DCAF10 0.126 19295130 Q9UL18 Q5QP82 AGO1 DCAF10 0.126 24778252 Q5QP82 P78362 DCAF10 SRPK2 0.183 26167880 Q5QP82 P19086 DCAF10 GNAZ 0.126 26186194 Q5QP82 Q13347 DCAF10 EIF3I 0.126 26186194 Q5QP82 Q15560 DCAF10 TCEA2 0.126 16169070

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 CCP110 DCAF10 MI:0045 experimental interaction detection MI:0461 interaction database DIRAS3 DCAF10 MI:0045 experimental interaction detection MI:0461 interaction database TRUB2 DCAF10 MI:0045 experimental interaction detection MI:0461 interaction database PAK4 DCAF10 MI:0362 inference MI:0461 interaction database UBC DCAF10 MI:0045 experimental interaction detection MI:0461 interaction database GNAZ DCAF10 MI:0045 experimental interaction detection MI:0461 interaction database PLK1 DCAF10 MI:0362 inference MI:0461 interaction database YPEL5 DCAF10 MI:0362 inference MI:0461 interaction database SRPK2 DCAF10 MI:0045 experimental interaction detection MI:0461 interaction database EIF3I DCAF10 MI:0045 experimental interaction detection MI:0461 interaction database CUL4A DCAF10 MI:0045 experimental interaction detection MI:0461 interaction database CUL4B DCAF10 MI:0045 experimental interaction detection MI:0461 interaction database TCEA2 DCAF10 MI:0045 experimental interaction detection MI:0461 interaction database DDB1 DCAF10 MI:0045 experimental interaction detection MI:0461 interaction database DCAF10 COPS6 MI:0045 experimental interaction detection MI:0461 interaction database DCAF10 SLX4 MI:0045 experimental interaction detection MI:0461 interaction database DCAF10 HDAC7 MI:0045 experimental interaction detection MI:0461 interaction database DCAF10 SCRN2 MI:0045 experimental interaction detection MI:0461 interaction database DCAF10 DDA1 MI:0045 experimental interaction detection MI:0461 interaction database DCAF10 ACTR8 MI:0045 experimental interaction detection MI:0461 interaction database DCAF10 PAK7 MI:0362 inference MI:0461 interaction database DCAF10 COPS7A MI:0045 experimental interaction detection MI:0461 interaction database DCAF10 AGO1 MI:0045 experimental interaction detection MI:0461 interaction database DCAF10 PPP2R2C MI:0045 experimental interaction detection MI:0461 interaction database DCAF10 JRKL MI:0045 experimental interaction detection MI:0461 interaction database DCAF10 SNX11 MI:0045 experimental interaction detection MI:0461 interaction database