Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 1 51719315 rs6701572 G A rs6701572 6.26E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 A intron GWASdb_drug 1 51709522 rs12728955 T C rs12728955 8.27E-05 Schizophrenia (cytomegalovirus infection interaction) HPOID:0100753 DOID:5419 T intron GWASdb_trait 1 51719315 rs6701572 G A rs6701572 6.26E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 A intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs6701572 1 51719315 51719315 intronic 0.817263 0.0876381624779561 GWAS of prostate cancer rs616055 1 51734386 51734386 intronic 0.572247 0.242416475432556 GWAS of prostate cancer rs12728955 1 51709522 51709522 intronic 0.330676 0.48059732442649206

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000123091.4 RNF11 612598