PTM - CPLM Gene Name UniProt ID Type Position Code RNF114; ZNF228; ZNF313 Q9Y508 Acetylation 102 K RNF114; ZNF228; ZNF313 Q9Y508 Acetylation 112 K RNF114; ZNF228; ZNF313 Q9Y508 Ubiquitination 126 K RNF114; ZNF228; ZNF313 Q9Y508 Ubiquitination 122 K RNF114; ZNF228; ZNF313 Q9Y508 Ubiquitination 96 K RNF114; ZNF228; ZNF313 Q9Y508 Ubiquitination 102 K RNF114; ZNF228; ZNF313 Q9Y508 Ubiquitination 112 K RNF114; ZNF228; ZNF313 Q9Y508 Ubiquitination 161 K RNF114; ZNF228; ZNF313 Q9Y508 Ubiquitination 38 K RNF114; ZNF228; ZNF313 Q9Y508 Ubiquitination 169 K RNF114; ZNF228; ZNF313 Q9Y508 Ubiquitination 61 K RNF114; ZNF228; ZNF313 Q9Y508 Ubiquitination 149 K RNF114; ZNF228; ZNF313 Q9Y508 Ubiquitination 58 K

PTM - dbPAF Gene Name UniProt ID Position Type Species RNF114; ZNF228; ZNF313 Q9Y508 113 Y Homo sapiens(Human) RNF114; ZNF228; ZNF313 Q9Y508 116 Y Homo sapiens(Human) RNF114; ZNF228; ZNF313 Q9Y508 165 S Homo sapiens(Human) RNF114; ZNF228; ZNF313 Q9Y508 186 Y Homo sapiens(Human) RNF114; ZNF228; ZNF313 Q9Y508 202 S Homo sapiens(Human) RNF114; ZNF228; ZNF313 Q9Y508 203 Y Homo sapiens(Human) RNF114; ZNF228; ZNF313 Q9Y508 209 Y Homo sapiens(Human) RNF114; ZNF228; ZNF313 Q9Y508 224 S Homo sapiens(Human)

PTM - PhosSNP Gene Name dbSNP ID Gene Mutation AA Mutation Mutation Position Code Peptide Score Modification Type RNF114; ZNF228; ZNF313 rs11550501 CGC->TGC R->C 186 Y MPWGDPNYRSANFRE 186 Phosphorylation TypeIII- RNF114; ZNF228; ZNF313 rs41303809 CGC->CAC R->H 186 Y MPWGDPNYRSANFRE 186 Phosphorylation TypeIII-

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9Y508 K102-ac Acetylation RkNFFLSkIRSHVAT Q9Y508 K112-ac Acetylation SHVATCskYQNyIME Q9Y508 S111-p Phosphorylation RSHVATCskYQNyIM Q9Y508 Y116-p Phosphorylation TCskYQNyIMEGVkA Q9Y508 S129-p Phosphorylation kATIkDAsLQPRNVP Q9Y508 Y186-p Phosphorylation MPWGDPNyRSANFRE Q9Y508 S202-p Phosphorylation IQRRHRFsyDTFVdy Q9Y508 Y203-p Phosphorylation QRRHRFsyDTFVdyD Q9Y508 Y209-p Phosphorylation syDTFVdyDVDEEDM Q9Y508 K102-sm Sumoylation RkNFFLSkIRSHVAT Q9Y508 K126-sm Sumoylation EGVkATIkDAsLQPR Q9Y508 K96-ub Ubiquitination TSCHGCRkNFFLSkI Q9Y508 K102-ub Ubiquitination RkNFFLSkIRSHVAT Q9Y508 K112-ub Ubiquitination SHVATCskYQNyIME Q9Y508 K122-ub Ubiquitination NyIMEGVkATIkDAs Q9Y508 K126-ub Ubiquitination EGVkATIkDAsLQPR Q9Y508 K161-ub Ubiquitination EGLVEHCkLFHSTDT Q9Y508 K169-ub Ubiquitination LFHSTDTkSVVCPIC

PTM - dbPTM UniProt ID Position Code Type Resources References Q9Y508 102 K Acetylation Swiss-Prot 1010711 19608861 Q9Y508 112 K Acetylation Swiss-Prot 1010711 19608861 Q9Y508 208 D Caspase Phosphositeplus.1010730 18724940 Q9Y508 102 K Ubiquitylation Phosphositeplus.1010730 21890473 Q9Y508 112 K Ubiquitylation Phosphositeplus.1010730 21890473 Q9Y508 122 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9Y508 126 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 Q9Y508 161 K Ubiquitylation Phosphositeplus.1010730 21890473 Q9Y508 96 K Ubiquitylation Phosphositeplus.1010730 21890473 Q9Y508 102 K Acetylation Phosphositeplus.1010730 19608861 Q9Y508 112 K Acetylation Phosphositeplus.1010730 19608861 Q9Y508 186 Y Phosphorylation Phosphositeplus.1010730 18180459 Q9Y508 102 K Acetylation HPRD 9.0 19608861 Q9Y508 112 K Acetylation HPRD 9.0 19608861 Q9Y508 113 Y Phosphorylation SysPTM 1.1 18785766 Q9Y508 116 Y Phosphorylation SysPTM 1.1 18785766

PTM - HPRD Symbol Position Code Type References RNF114 102 K Acetylation 19608861 RNF114 112 K Acetylation 19608861

PTM - UniProt UniProt ID Position Type PMIDs Q9Y508 102 N6-acetyllysine 19608861 Q9Y508 112 N6-acetyllysine 19608861

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 55905 120991 - K Ubiquitination 21987572 55905 120991 - K Ubiquitination 21139048 55905 120991 - K Ubiquitination 21890473 55905 120991 - K Ubiquitination 21906983 55905 120991 - K Ubiquitination 22505724 55905 120991 - K Ubiquitination 21963094 55905 120991 - K Ubiquitination 23000965 55905 120991 - K Sumoylation 25027693 55905 120991 - K Ubiquitination 25015289 55905 120991 - K Ubiquitination 25165885

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID RNF114 Homo sapiens (Human) 89 "89,GLVEHCKLFHSTD" 89:21890473 RNF114 Homo sapiens (Human) 126; 122 "126,GVKATIKDASLQP; 122,YIMEGVKATIKDA" 126:21139048; 122:21139048 RNF114 Homo sapiens (Human) 102; 96; 112; 126; 161; 122 "102,KNFFLSKIRSHVA; 96,SCHGCRKNFFLSK; 112,HVATCSKYQNYIM; 126,GVKATIKDASLQP; 161,GLVEHCKLFHSTD; 122,YIMEGVKATIKDA" 102:21890473; 96:21890473; 112:21890473; 126:21890473; 161:21890473; 122:21890473 RNF114 Homo sapiens (Human) 102; 96; 112; 126; 161; 122 "102,KNFFLSKIRSHVA; 96,SCHGCRKNFFLSK; 112,HVATCSKYQNYIM; 126,GVKATIKDASLQP; 161,GLVEHCKLFHSTD; 122,YIMEGVKATIKDA" "102:21890473; 96:21890473; 112:21890473; 126:21890473,21906983; 161:21890473; 122:21890473,21906983" RNF114 Homo sapiens (Human) 102; 96; 112; 126; 161; 122 "102,KNFFLSKIRSHVA; 96,SCHGCRKNFFLSK; 112,HVATCSKYQNYIM; 126,GVKATIKDASLQP; 161,GLVEHCKLFHSTD; 122,YIMEGVKATIKDA" "102:21890473; 96:21890473; 112:21890473; 126:21890473,21906983; 161:21890473; 122:21890473,21906983"