PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus BIRC3 RBCK1 23524849 biogrid,intact exp GP G GP G G GP P GP G GP G GP G GP P G GP GP GP GP GP TAB3 RBCK1 17449468 innatedb,biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PML RBCK1 15833741 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TRIM65 RBCK1 22493164 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G HSP90AA1 RBCK1 23912458 biogrid exp GP GP G G G GP G G GP G G G G G G G GP G G G GP G G G G G G GP G UBE2D2 RBCK1 17006537 biogrid exp GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G NR2C2 RBCK1 17449468 biogrid exp G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G UBC RBCK1 17006537,18303026,22139374,20005846,19796170,23986494 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBA52 RBCK1 21455181 dip exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G USP7 RBCK1 23105109 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2K RBCK1 19549727 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G LDLRAD4 RBCK1 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP P G TRAF1 RBCK1 21903422 innatedb,biogrid exp G G G G GP GP G G GP G GP G G GP G G GP G G G G G G G GP G G G DDX58 RBCK1 21292167 biogrid exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G UBE2G1 RBCK1 19549727 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PCGF2 RBCK1 22493164 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UHRF2 RBCK1 22493164 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NR1I2 RBCK1 23160820 biogrid exp G G G G G RBCK1 NOD2 23818254,22607974 biogrid exp P G GP P P P GP P P P P P P P P P GP P BACH1 RBCK1 17682061 hprd,biogrid exp GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G RBCK1 MKRN2 22493164 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G LTBR RBCK1 26186194 biogrid exp GP G G GP P G G G GP G GP GP G GP P G G G GP G GP G GP GP GP GP G OTUD6A RBCK1 23105109 biogrid exp P P P P P P P P P P P P P P P P P P P P P UBE2D3 RBCK1 17006537,17682061,21292167,12629548 biogrid exp GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G APP RBCK1 21832049 biogrid exp G GP G G GP GP G G GP G G G G G G GP GP G GP G GP GP G G GP G G GP G SOCS6 RBCK1 16643902 hprd exp GP GP G P GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP P GP GP G RBCK1 USP21 23105109 biogrid exp GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G NDUFAF3 RBCK1 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RBCK1 USP15 23105109 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TNFAIP3 RBCK1 23105109,23032186 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G PRKCA RBCK1 25118570 biogrid exp G GP G G GP GP G GP GP G GP G G GP G GP GP G GP G GP G G GP GP G GP GP G USP2 RBCK1 23105109 biogrid exp GP G P GP G GP P G GP GP GP GP P GP GP GP G GP P GP GP GP P P GP G PARK2 RBCK1 24722188 biogrid exp P GP G P GP G GP GP G GP P P G P GP GP P G P GP GP GP P GP G RBCK1 ARNT2 24722188 biogrid exp P P G GP G GP G G GP G G GP G G G G GP G G G GP G OTULIN RBCK1 24726327,24726323,23708998 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP P G GP GP GP GP G UBE2S RBCK1 19549727 biogrid,intact exp G G G G G G G G GP G G G GP G G G G G G G G G G G GP G TRIM25 RBCK1 21292167 biogrid exp G GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G PAN2 RBCK1 23105109 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SYCE1 RBCK1 25416956 biogrid,intact exp P P P P P P P P P P GP RBCK1 UCHL5 23105109 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2N RBCK1 19549727,25260751 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G PSMD4 RBCK1 22517668,19796170 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G ESR1 RBCK1 23912458,23042805 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G RBCK1 RNF181 22493164 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G NAA10 RBCK1 25416956 biogrid,intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBA1 RBCK1 25260751 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2U RBCK1 19549727 biogrid,intact exp P P P P P P P P P P P P P P P P P P P P GP NEDD4 RBCK1 19953087 biogrid exp GP GP G GP P G GP GP GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP P G RBCK1 RBCK1 18303026,25416956,16083853 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RBCK1 UBE2D4 19549727 biogrid,intact exp GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G IRF3 RBCK1 18711448 innatedb exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TRIML1 RBCK1 22493164 biogrid,intact exp P P P P P P P P P P P P P P P GP UBE2V1 RBCK1 25260751 intact exp UBE2D1 RBCK1 17006537 biogrid exp GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G OTUB2 RBCK1 23105109 biogrid exp P P P P P P P P GP MAP3K1 RBCK1 25260751 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RBCK1 FKBPL 23912458 biogrid exp P P G GP P P G P P P P GP P P P P G P P GP GP G TSSK3 RBCK1 25416956 biogrid,intact exp P P P P P P P P P P P P P P GP TNF RBCK1 23104095,20005846,25911380,23032186,23955153 biogrid,intact,dip exp G G G G G GP G G GP G G G GP G GP GP G GP G G G G GP G GP G G USP32 RBCK1 23105109 biogrid exp, ortho GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP G G GP G GP GP G PRKCB RBCK1 18303026,17069764,23042805,17121852 biogrid exp, ortho GP GP G G GP GP G G GP G GP G GP GP G G GP GP GP G G GP GP G G GP GP GP G USP49 RBCK1 23105109 biogrid exp, ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G RBCK1 SHARPIN 21455180,24726327,21455181,21709223,23032186 innatedb,biogrid,intact,dip exp, ortho GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP GP G CREBBP RBCK1 15833741, 25402006 hprd,bci exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2L3 RBCK1 17006537,18303026,19549727, 25402006 biogrid,intact exp, ortho, pred GP G G G G GP G GP GP G GP G G G G GP GP G GP G G G GP GP GP G GP GP G RBCK1 IKBKG 21709223,21455180,19675569,21811235,23732909,20098747,23986494,23032186, 25402006 innatedb,biogrid,intact,dip exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF31 RBCK1 24726327,17006537,doi:10.1038/embor.2012.105,19136968,23708998,17069764,22791023,22430200,21455180,doi:10.1038/embor.2012.24,23032187,20005846, 25402006 innatedb,hprd,biogrid,mint,intact,dip exp, ortho, pred P P G G GP GP P P G GP GP GP P GP GP P GP G GP P P GP GP GP P GP RBCK1 TRAF6 17449468, 25402006, 23023127 innatedb,biogrid exp, pred GP GP G G GP G G GP GP G GP GP GP G G GP G GP G G GP GP GP G GP GP GP GP G IREB2 RBCK1 17822790,12629548, 21836163 biogrid,i2d exp, pred GP GP G G G GP G GP GP G GP GP G GP G GP GP G GP G GP GP GP GP GP GP GP GP G TRIM21 RBCK1 22493164, 23023127 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2L6 RBCK1 25416956,19549727, 25402006 biogrid,intact exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G MAP3K7 RBCK1 17449468, 25402006 innatedb,biogrid exp, pred GP GP G G G GP G G GP G G GP GP G G G GP G GP G GP GP G G G G GP GP G RIPK1 RBCK1 17449468, 25402006 innatedb,biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RBCK1 TAB2 17449468, 21836163 innatedb,biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G EYA2 RBCK1 ortho GP P P P G P P GP P P P G P P P P GP GP GP P P P GP GP G PRKCZ RBCK1 ortho G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP P GP GP GP GP EYA1 RBCK1 ortho G G G G IKBKB RBCK1 25402006 ortho, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G CHUK RBCK1 25402006 ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DDX42 RBCK1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RPS16 RBCK1 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TRIM28 RBCK1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ACTG1 RBCK1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HSPA1A, HSPA1B RBCK1 25402006 pred P P P P P P P P P P P P P P P P P P P P P P TXLNA RBCK1 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RPS3 RBCK1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G SQSTM1 RBCK1 25402006 pred GP GP G G GP G G G GP G GP GP GP GP G GP G GP GP G GP GP GP GP GP GP GP GP G BCL10 RBCK1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ELF4 RBCK1 21836163 pred GP GP G G G G GP GP GP GP G G GP GP P G GP GP P GP GP GP GP G RBCK1 CPEB1 21836163 pred P P G P GP G P P G P P P P P GP G P G P P P P P GP GP TNIP2 RBCK1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP GP GP GP G DDB1 RBCK1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TFG RBCK1 25402006 pred G GP G G GP GP G GP GP G GP G G GP G GP GP GP GP G GP GP GP G GP G GP GP G ESYT1 RBCK1 25402006 pred G G G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP G GP GP GP GP G DAP RBCK1 23023127 pred G GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP G GP GP G RPS10 RBCK1 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G RPN1 RBCK1 25402006 pred G GP G G GP GP G GP GP G G GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G SLC25A6 RBCK1 25402006 pred G GP G G GP GP G G G G GP GP G G G GP GP G GP G G G GP G GP G GP GP G RPS5 RBCK1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRAF3IP2 RBCK1 25402006 pred GP GP P P G P GP GP GP GP GP G GP P GP GP G GP GP GP P GP GP GP P G FLNA RBCK1 25402006 pred G G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP G G G G G GP GP G PPP1CC RBCK1 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP GP GP GP G MAFG RBCK1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RBCK1 NCOA3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RBCK1 USP18 25402006 pred GP P G G GP G G G G G P GP P G G G GP G RPS20 RBCK1 25402006 pred P P P P P P P P P P P P P P P P P P P P P BRCA1 RBCK1 25402006 pred P P G GP P P P P P P P GP P P P P P P P P P P GP RPLP0 RBCK1 25402006 pred GP GP G G G GP G G GP G G G GP G G GP GP G GP G GP G GP G GP GP GP GP G SENP7 RBCK1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P GCN1L1 RBCK1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CARD10 RBCK1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RBCK1 TBK1 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRIB3 RBCK1 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ARID3A RBCK1 21836163 pred GP G G G GP GP G G G G GP G GP GP G GP GP G GP G GP GP G GP GP GP GP GP G VIM RBCK1 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G G GP GP GP G G G G G G GP G GP G ECM29 RBCK1 25402006 pred G GP G G G G G G GP G GP GP GP G G GP G GP GP G G GP GP G GP G GP GP G MYO1C RBCK1 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G RBCK1 SENP2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MAFK RBCK1 25402006 pred G G G G GP G G GP GP G G G G G G GP G G GP G GP G G G GP G GP G G RBCK1 TRIM17 21836163 pred P P P P P P P P P P P P P P P P P P GP GNL3 RBCK1 21836163 pred P GP P P P P P P P P G GP P P GP GP GP P P P P P P RBCK1 MALT1 25402006 pred G G GP G G G G G G GP G G G G G G G G G G G G GP G RBCK1 CYLD 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP IRAK1 RBCK1 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G BIRC2 RBCK1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9BYM8 pull down 23955153 - C 8 Q9BYM8 anti bait coimmunoprecipitation 21455180 - C 4 Q9BYM8 anti tag coimmunoprecipitation 21455180 - C 4 Q9BYM8 anti tag coimmunoprecipitation 21455180 - C 3 Q9Y6K9 Q9BYM8 anti tag coimmunoprecipitation 21709223 physical association X 2 Q9Y6K9 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association X 2 Q9Y6K9 Q9BYM8 anti tag coimmunoprecipitation 21709223 physical association X 2 Q9Y6K9 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association X 2 Q9Y6K9 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association X 2 P01375 Q9BYM8 pull down 23955153 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association X 2 Q96EP0 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 21455181 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 24141947 physical association X 2 Q96EP0 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 21455181 physical association X 2 Q96EP0 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 21455181 physical association X 2 Q96EP0 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q96EP0 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association X 2 Q96EP0 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q96EP0 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 21455181 physical association X 2 Q96EP0 Q9BYM8 pull down 21455180 physical association X 2 Q96EP0 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q96EP0 Q9BYM8 pull down 21455180 physical association X 2 Q96EP0 Q9BYM8 pull down 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti tag coimmunoprecipitation 21455181 physical association X 2 Q9H0F6 Q9BYM8 anti tag coimmunoprecipitation 21455181 physical association X 2 Q9H0F6 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 pull down 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti tag coimmunoprecipitation 21455181 physical association X 2 Q9H0F6 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti tag coimmunoprecipitation 21455181 physical association X 2 Q9H0F6 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q9H0F6 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association X 2 Q9BYM8 anti tag coimmunoprecipitation 21709223 - C 3 Q9BYM8 anti bait coimmunoprecipitation 21455180 - C 5 Q9BYM8 P62987 pull down 21455181 direct interaction X 2 Q9BYM8 P62987 pull down 22158122 direct interaction X 2 Q9BYM8 P62987 isothermal titration calorimetry 21455181 direct interaction X 2 Q9BYM8 P62987 pull down 21455181 direct interaction X 2 Q9BYM8 P62987 pull down 21455181 direct interaction X 2 Q9BYM8 P62987 pull down 22158122 direct interaction X 2 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 molecular sieving 21455180 physical association C 3 Q9BYM8 anti tag coimmunoprecipitation 21455181 physical association C 3 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 pull down 21455180 physical association C 3 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 pull down 21455180 physical association C 3 Q9BYM8 anti tag coimmunoprecipitation 21455181 physical association C 3 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 anti tag coimmunoprecipitation 21455181 physical association C 3 Q9BYM8 anti bait coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 anti tag coimmunoprecipitation 24141947 physical association C 3 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 pull down 21455180 physical association C 3 Q9BYM8 molecular sieving 21455180 physical association C 3 Q9BYM8 anti tag coimmunoprecipitation 21455180 physical association C 3 Q9BYM8 anti bait coimmunoprecipitation 21455180 - C 5 Q9BYM8 anti bait coimmunoprecipitation 21455180 - C 6 Q9BYM8 anti bait coimmunoprecipitation 23032186 association C 4 Q9BYM8 anti bait coimmunoprecipitation 23032186 association C 5 Q9BYM8 P0CK53 two hybrid 17446270 physical association X 2 Q9BYM8 Q5VVX9 two hybrid array 19549727 physical association X 2 Q9BYM8 A0A024RA90 two hybrid array 19549727 physical association X 2 Q9BYM8 Q9P0P0 two hybrid array 22493164 physical association X 2 Q9BYM8 P41227 two hybrid prey pooling approach 25416956 physical association X 2 Q9BYM8 A4FU71 two hybrid prey pooling approach 25416956 physical association X 2 Q9BYM8 Q8N0S2 two hybrid prey pooling approach 25416956 physical association X 2 Q9BYM8 P41227 two hybrid array 25416956 physical association X 2 Q9BYM8 A4FU71 two hybrid array 25416956 physical association X 2 Q9BYM8 Q8N0S2 two hybrid array 25416956 physical association X 2 Q9BYM8 P41227 validated two hybrid 25416956 physical association X 2 Q9BYM8 Q8N0S2 validated two hybrid 25416956 physical association X 2 Q9BYM8 A4FU71 validated two hybrid 25416956 physical association X 2 Q9BYM8 ubiquitinase assay 25260751 ubiquitination reaction C 5 Q9BYM8 anti tag coimmunoprecipitation 23032186 association C 6 Q9BYM8 anti tag coimmunoprecipitation 21903422 association C 6 Q9BYM8 anti bait coimmunoprecipitation 21811235 association C 3 Q9Y6K9 Q9BYM8 protein array 20098747 direct interaction X 2 A0A024R1A4 Q9BYM8 two hybrid array 19549727 physical association X 2 P09022 Q9BYM8 pull down 23088713 physical association X 2 P09022 Q9BYM8 bimolecular fluorescence complementation 23088713 physical association X 2 P09022 Q9BYM8 two hybrid 23088713 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 17006537 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 17006537 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 17006537 physical association X 2 Q96EP0 Q9BYM8 molecular sieving 17006537 association X 2 Q96EP0 Q9BYM8 pull down 17006537 direct interaction X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 22430200 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 22430200 physical association X 2 Q96EP0 Q9BYM8 surface plasmon resonance 22430200 direct interaction X 2 Q96EP0 Q9BYM8 surface plasmon resonance 22430200 direct interaction X 2 Q96EP0 Q9BYM8 surface plasmon resonance 22430200 direct interaction X 2 Q96EP0 Q9BYM8 surface plasmon resonance 22430200 direct interaction X 2 Q96EP0 Q9BYM8 surface plasmon resonance 22430200 direct interaction X 2 Q96EP0 Q9BYM8 x-ray crystallography 22430200 direct interaction X 2 Q96EP0 Q9BYM8 nuclear magnetic resonance 22430200 direct interaction X 2 Q96EP0 Q9BYM8 molecular sieving 22430200 direct interaction X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 22430200 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 22430200 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 22430200 physical association X 2 Q96EP0 Q9BYM8 anti tag coimmunoprecipitation 22430200 physical association X 2 Q96EP0 Q9BYM8 isothermal titration calorimetry 22791023 direct interaction X 2 Q9JLY0 Q9BYM8 two hybrid array 16643902 physical association X 2 Q9JLY0 Q9BYM8 anti tag coimmunoprecipitation 16643902 physical association X 2 Q9JLY0 Q9BYM8 anti tag coimmunoprecipitation 16643902 physical association X 2 Q9JLY0 Q9BYM8 anti bait coimmunoprecipitation 16643902 physical association X 2 Q9JLY0 Q9BYM8 two hybrid array 16643902 physical association X 2 O14933 Q9BYM8 two hybrid array 19549727 physical association X 2 O14933 Q9BYM8 two hybrid prey pooling approach 25416956 physical association X 2 O14933 Q9BYM8 two hybrid array 25416956 physical association X 2 O14933 Q9BYM8 validated two hybrid 25416956 physical association X 2 Q4VA12 Q9BYM8 anti tag coimmunoprecipitation 21903422 physical association X 2 Q9BU61 Q9BYM8 two hybrid prey pooling approach 25416956 physical association X 2 Q9BU61 Q9BYM8 two hybrid array 25416956 physical association X 2 Q9BU61 Q9BYM8 validated two hybrid 25416956 physical association X 2 Q9BYM8 anti tag coimmunoprecipitation 23032186 association C 4 Q9BYM8 anti bait coimmunoprecipitation 23032186 association C 4 Q9BYM8 anti tag coimmunoprecipitation 23524849 association C 20 Q9BYM8 pull down 23104095 association C 4 Q9BYM8 P62253 two hybrid array 19549727 physical association X 2 Q9BYM8 P61088 two hybrid array 19549727 physical association X 2 Q9BYM8 A0A024R1V6 two hybrid array 22493164 physical association X 2 Q9BYM8 Q9H000 two hybrid array 22493164 physical association X 2 Q9BYM8 Q96PU4 two hybrid array 22493164 physical association X 2 Q9BYM8 Q6PJ69 two hybrid array 22493164 physical association X 2 Q9BYM8 Q8N9V2 two hybrid array 22493164 physical association X 2 Q9BYM8 Q9BYM8 two hybrid array 25416956 physical association X 2 Q9BYM8 Q96PN8 two hybrid prey pooling approach 25416956 physical association X 2 Q9BYM8 Q96PN8 two hybrid array 25416956 physical association X 2 Q9BYM8 Q96PN8 validated two hybrid 25416956 physical association X 2 P19474 Q9BYM8 two hybrid array 22493164 physical association X 2 Q16763 Q9BYM8 two hybrid array 19549727 physical association X 2 Q7CHB5 Q9BYM8 two hybrid pooling approach 20711500 physical association X 2 Q8XC86 Q9BYM8 two hybrid 25519916 physical association X 2 Q8XC86 Q9BYM8 two hybrid 25519916 physical association X 2 B3KSH4 Q9BYM8 two hybrid array 19549727 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBE2U RBCK1 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101186|BIOGRID_124231 bait|bait prey|prey UBE2G1 RBCK1 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101093|BIOGRID_124227 bait|bait prey|prey APP RBCK1 MI:0096(pull down) 21832049 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_229502 prey bait CREBBP RBCK1 MI:0492(in vitro) 15833741 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_26733 - - UBE2N RBCK1 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101113|BIOGRID_124230 bait|bait prey|prey PAN2 RBCK1 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248235 bait prey UBE2D3 RBCK1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12629548,17682061,21292167 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_117922|BIOGRID_226130|BIOGRID_225907 prey|prey|prey bait|bait|bait UHRF2 RBCK1 MI:0415(enzymatic study)|MI:0397(two hybrid array) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_284020|UniProt_122532 prey|bait bait|prey SOCS6 RBCK1 MI:0493(in vivo)|MI:0493(in vivo) 16643902 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|- MI:0468(hprd)|MI:0468(hprd) HPRD_32045|HPRD_39868 -|- -|- TRIM21 RBCK1 MI:0415(enzymatic study)|MI:0397(two hybrid array) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_284139|UniProt_122494 bait|bait prey|prey UBC RBCK1 MI:0415(enzymatic study)|MI:0401(biochemical)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17006537,18303026,18781797,19796170,21139048,21890473,21906983,21963094,21987572,22053931,22139374,22505724,23000965,23986494 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_163064|BIOGRID_253589|BIOGRID_266930|BIOGRID_176763|BIOGRID_117367|BIOGRID_168874|BIOGRID_223313|BIOGRID_162284|BIOGRID_268061|BIOGRID_201303|BIOGRID_201302|BIOGRID_264386|BIOGRID_188062|BIOGRID_289203|BIOGRID_178204 bait|prey|bait|bait|prey|bait|bait|bait|bait|prey|prey|bait|prey|prey|bait prey|bait|prey|prey|bait|prey|prey|prey|prey|bait|bait|prey|bait|bait|prey FAM105B RBCK1 MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography) 23708998,24726327 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_310384|BIOGRID_282399 bait|bait prey|prey TRIML1 RBCK1 MI:0397(two hybrid array)|MI:0415(enzymatic study) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_122534|BIOGRID_284003 prey|prey bait|bait RBCK1 FKBPL MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 23912458 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_284842|BIOGRID_284843|BIOGRID_284846 prey|bait|prey bait|prey|bait RBCK1 USP21 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248215 prey bait NEDD4 RBCK1 MI:0415(enzymatic study) 19953087 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_164703 bait prey USP2 RBCK1 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248163 bait prey USP32 RBCK1 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248222 bait prey TAB3 RBCK1 MI:0004(affinity chromatography technology) 17449468 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_199348 prey bait RNF31 RBCK1 MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0493(in vivo)|MI:0114(x-ray crystallography)|MI:0007(anti tag coimmunoprecipitation)|MI:0114(x-ray crystallography)|MI:0071(molecular sieving)|MI:0071(molecular sieving)|MI:0096(pull down)|MI:0007(anti tag coimmunoprecipitation)|MI:0071(molecular sieving)|MI:0071(molecular sieving)|MI:0004(affinity chromatography technology)|MI:0071(molecular sieving)|MI:0065(isothermal titration calorimetry)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0401(biochemical)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0401(biochemical)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0007(anti tag coimmunoprecipitation)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0007(anti tag coimmunoprecipitation)|MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography) 17006537,17069764,20005846,22430200,22791023,23032187,23708998,24726327 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|-|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0914(association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|MI:0468(hprd)|(intact)|MI:0471(mint)|(intact)|(intact)|(intact)|(biogrid)|MI:0471(mint)|(intact)|(intact)|(biogrid)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|(intact)|(biogrid)|(intact)|(intact)|(biogrid)|(intact) UniProt_123318|UniProt_123319|HPRD_31264|UniProt_123331|MINT_51680|UniProt_123330|UniProt_88175|UniProt_88174|BIOGRID_218372|MINT_84085|UniProt_88178|UniProt_88177|BIOGRID_200615|UniProt_88176|UniProt_125808|MINT_84082|MINT_84081|MINT_84084|MINT_84083|BIOGRID_253588|UniProt_123329|BIOGRID_199047|BIOGRID_253587|BIOGRID_199048|BIOGRID_199049|BIOGRID_282397|UniProt_123320|MINT_51678|UniProt_123322|UniProt_123321|MINT_51679|MINT_51676|UniProt_123324|UniProt_123323|MINT_51677|UniProt_123326|BIOGRID_141247|UniProt_123325|UniProt_123328|BIOGRID_310373|UniProt_123327 neutral component|prey|-|neutral component|bait|bait|bait|neutral component|bait|bait|bait|prey|bait|bait|prey|neutral component|bait|prey|bait|bait|bait|bait|prey|bait|bait|bait|prey|bait|prey|prey|prey|bait|neutral component|prey|neutral component|prey|bait|prey|bait|bait|prey neutral component|bait|-|neutral component|prey|prey|prey|neutral component|prey|prey|prey|bait|prey|prey|bait|neutral component|prey|bait|prey|prey|prey|prey|bait|prey|prey|prey|bait|prey|bait|bait|bait|prey|neutral component|bait|neutral component|bait|prey|bait|prey|prey|bait TRIM65 RBCK1 MI:0415(enzymatic study)|MI:0397(two hybrid array) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_284089|UniProt_122533 prey|bait bait|prey MAP3K7 RBCK1 MI:0004(affinity chromatography technology) 17449468 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_199349 prey bait TRAF1 RBCK1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_156001|BIOGRID_155838 bait|bait prey|prey NFKBIA RBCK1 MI:0004(affinity chromatography technology) 22605335 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_192125 prey bait NR2C2 RBCK1 MI:0004(affinity chromatography technology) 17449468 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_207249 prey bait PRKCB RBCK1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17069764,17121852,18303026,23042805 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_217661|BIOGRID_200612|BIOGRID_117369|BIOGRID_195843|BIOGRID_195841 prey|bait|bait|prey|bait bait|prey|prey|bait|prey UBE2S RBCK1 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101434|BIOGRID_124570 bait|bait prey|prey NR1I2 RBCK1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 23160820 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_247675|BIOGRID_247676|BIOGRID_247677|BIOGRID_247678 bait|bait|prey|prey prey|prey|bait|bait TNFAIP3 RBCK1 MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 23032186,23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_219126|BIOGRID_248259 bait|bait prey|prey PML RBCK1 MI:0428(imaging technique) 15833741 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_207496 prey bait DDX58 RBCK1 MI:0004(affinity chromatography technology) 21292167 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_158746 bait prey PSMD4 RBCK1 MI:0004(affinity chromatography technology)|MI:0096(pull down) 19796170,22517668 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_188060|BIOGRID_208507 bait|bait prey|prey IREB2 RBCK1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12629548,17822790 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_133979|BIOGRID_200265|BIOGRID_200264|BIOGRID_133980 prey|bait|prey|prey bait|prey|bait|bait OTUD6A RBCK1 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248250 bait prey UBE2K RBCK1 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_124571 bait prey RBCK1 HIP2 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_101198 prey bait RBCK1 NOD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22607974,23818254 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_187980|BIOGRID_282695 prey|prey bait|bait RBCK1 MKRN2 MI:0415(enzymatic study)|MI:0397(two hybrid array) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_283961|UniProt_122530 bait|prey prey|bait RBCK1 SHARPIN MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 23032186,24726327 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(biogrid)|(intact)|(intact) BIOGRID_310386|BIOGRID_219086|UniProt_125826|UniProt_125832 prey|prey|prey|prey bait|bait|bait|prey BIRC3 RBCK1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 23524849 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_130010|BIOGRID_272923 bait|bait prey|prey RBCK1 RNF181 MI:0415(enzymatic study)|MI:0397(two hybrid array) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_284061|UniProt_122531 bait|prey prey|bait TNF RBCK1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 20005846,23032186,23104095 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(biogrid)|(intact)|(intact) BIOGRID_219089|BIOGRID_141246|UniProt_124328|UniProt_125831 bait|bait|bait|bait prey|prey|prey|prey OTUB2 RBCK1 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248243 bait prey RBCK1 UCHL5 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248157 prey bait RBCK1 USP15 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248202 prey bait RBCK1 TRAF6 MI:0004(affinity chromatography technology) 17449468 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_199350 bait prey PCGF2 RBCK1 MI:0397(two hybrid array)|MI:0415(enzymatic study) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_122529|BIOGRID_284051 bait|prey prey|bait RBCK1 IKBKG MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0089(protein array)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation) 20098747,21709223,21811235,23032186,23732909,23986494 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association) (intact)|(intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact) UniProt_125829|UniProt_116441|BIOGRID_289208|BIOGRID_220043|UniProt_105559|BIOGRID_256687|BIOGRID_219082|BIOGRID_123932|BIOGRID_281385|BIOGRID_289207|UniProt_125825 prey|prey|prey|prey|bait|prey|prey|prey|prey|prey|prey bait|bait|bait|bait|prey|bait|bait|bait|bait|bait|bait USP7 RBCK1 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248191 bait prey RBCK1 UBE2D4 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101450|BIOGRID_124569 prey|prey bait|bait USP49 RBCK1 MI:0018(two hybrid) 23105109 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_248234 bait prey TRIM25 RBCK1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21292167 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0403(colocalization) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_158752|BIOGRID_158744|BIOGRID_158757|BIOGRID_158750 prey|bait|prey|bait bait|prey|bait|prey HSP90AA1 RBCK1 MI:0018(two hybrid)|MI:0018(two hybrid) 23912458 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_284852|BIOGRID_284850 bait|prey prey|bait HOXA1 RBCK1 MI:0004(affinity chromatography technology) 23088713 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_249137 prey bait UBE2L3 RBCK1 MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 18303026,19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(biogrid)|(biogrid) UniProt_101100|BIOGRID_225666|BIOGRID_124228 bait|prey|bait prey|bait|prey ESR1 RBCK1 MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 23042805,23912458 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_217660|BIOGRID_284851|BIOGRID_217657|BIOGRID_217658|BIOGRID_217659|BIOGRID_284848 bait|prey|prey|bait|prey|bait prey|bait|bait|prey|bait|prey RBCK1 TAB2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17449468 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_199353|BIOGRID_199347 prey|bait bait|prey RIPK1 RBCK1 MI:0004(affinity chromatography technology) 17449468 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_199351 prey bait UBE2L6 RBCK1 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101124|BIOGRID_124229 bait|bait prey|prey BACH1 RBCK1 MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17682061 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0468(hprd)|(biogrid)|(biogrid) BIOGRID_117921|HPRD_33504|BIOGRID_117918|BIOGRID_117919 prey|-|bait|prey bait|-|prey|bait

PPI - HINT Gene A Gene B PMID Method Quality LDLRAD4 RBCK1 26186194 0004 HT TNF RBCK1 26670046,20005846,23032186,25911380,23032186,23955153,25911380,23104095 0004,0004,0007,0096,0004,0096,0004,0096 LC PRKCB RBCK1 23042805,17069764,17121852 0004,0004,0004 LC UBC RBCK1 23986494,21455181,18303026,21455181,19796170,22158122,20005846,22139374,23986494,22139374,19796170 0096,0096,0004,0065,0004,0096,0096,0096,0415,0114,0096 LC LTBR RBCK1 26186194 0004 HT IREB2 RBCK1 12629548,12629548,17822790,12629548 0415,0018,0004,0004 LC PSMD4 RBCK1 22517668,19796170 0096,0004 LC UBE2D3 RBCK1 12629548,17682061,17006537,21292167 0096,0096,0096,0096 LC UBE2L3 RBCK1 18303026,17006537 0096,0096 LC TRAF1 RBCK1 21903422,25996949,21903422 0096,0004,0004 LC OTULIN RBCK1 26670046,23708998,24726327,24726323 0004,0004,0004,0004 LC RNF31 RBCK1 17006537,22430200,17069764,21455180,23708998,21455180,24726327,22430200,26670046,23032187,26525107,22791023,17006537,22791023,17006537,21455180,26577923,22430200,24141947,22430200,17006537,22430200,22430200,22430200,20005846,17006537,21455180,21455181 0401,0071,0004,0096,0004,0007,0004,0004,0004,0004,0004,0065,0071,0096,0096,0004,0004,0114,0007,0107,0004,0007,0096,0077,0004,0007,0006,0007 LC RBCK1 SHARPIN 26670046,21455181,23032186,21455180,23032186,21455180,21455180,24726327,21455180 0004,0007,0006,0096,0004,0007,0006,0004,0004 LC RBCK1 NOD2 26670046,22607974,23818254 0004,0004,0004 LC RBCK1 Q9UBT1 23042805,23042805,23912458 0004,0096,0004 LC RBCK1 IKBKG 23986494,20098747,20098747,21811235,21709223,21709223,23032186,23032186,21455180,23732909,21455180,21811235 0096,0096,0089,0004,0004,0007,0006,0004,0007,0004,0004,0006 LC LDLRAD4 RBCK1 26186194 0004 HT LTBR RBCK1 26186194 0004 HT TNF RBCK1 26670046,20005846,23032186,25911380,23032186,23955153,25911380,23104095 0004,0004,0007,0096,0004,0096,0004,0096 LC PRKCB RBCK1 23042805,17069764,17121852 0004,0004,0004 LC UBC RBCK1 23986494,21455181,18303026,21455181,19796170,22158122,20005846,22139374,23986494,22139374,19796170 0096,0096,0004,0065,0004,0096,0096,0096,0415,0114,0096 LC IREB2 RBCK1 12629548,12629548,17822790,12629548 0415,0018,0004,0004 LC PSMD4 RBCK1 22517668,19796170 0096,0004 LC UBE2D3 RBCK1 12629548,17682061,17006537,21292167 0096,0096,0096,0096 LC UBE2L3 RBCK1 18303026,17006537 0096,0096 LC TRAF1 RBCK1 21903422,25996949,21903422 0096,0004,0004 LC OTULIN RBCK1 26670046,23708998,24726327,24726323 0004,0004,0004,0004 LC RNF31 RBCK1 17006537,22430200,17069764,21455180,23708998,21455180,24726327,22430200,26670046,23032187,26525107,22791023,17006537,22791023,17006537,21455180,26577923,22430200,24141947,22430200,17006537,22430200,22430200,22430200,20005846,17006537,21455180,21455181 0401,0071,0004,0096,0004,0007,0004,0004,0004,0004,0004,0065,0071,0096,0096,0004,0004,0114,0007,0107,0004,0007,0096,0077,0004,0007,0006,0007 LC RBCK1 SHARPIN 26670046,21455181,23032186,21455180,23032186,21455180,21455180,24726327,21455180 0004,0007,0006,0096,0004,0007,0006,0004,0004 LC RBCK1 NOD2 26670046,22607974,23818254 0004,0004,0004 LC RBCK1 Q9UBT1 23042805,23042805,23912458 0004,0096,0004 LC RBCK1 IKBKG 23986494,20098747,20098747,21811235,21709223,21709223,23032186,23032186,21455180,23732909,21455180,21811235 0096,0096,0089,0004,0004,0007,0006,0004,0007,0004,0004,0006 LC HIP2 RBCK1 19549727 0397 HT SOCS6 RBCK1 16643902 0018 LC BACH1 RBCK1 17682061,17682061 0415,0004 LC UBE2L6 RBCK1 19549727,25416956,25416956,25416956,25416956,19549727 0397,1112,0397,0018,1356,0018 HT PARK2 RBCK1 24722188 0018 HT NR1I2 RBCK1 23160820,23160820,23160820 0096,0004,0018 LC USP2 RBCK1 23105109 0018 LC PRKCB RBCK1 18303026 0415 LC UBC RBCK1 23986494,21455181,21455181,17006537,22139374,23986494,22139374 0096,0096,0065,0415,0096,0415,0114 LC PRKCA RBCK1 25118570,25118570 0004,0415 LC TRIM21 RBCK1 22493164,22493164 0018,0397 HT TNFAIP3 RBCK1 23105109 0018 LC UBA1 RBCK1 25260751 0997 LC NFKBIA RBCK1 22605335 0415 LC PCGF2 RBCK1 22493164,22493164 0018,0397 HT NAA10 RBCK1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT IREB2 RBCK1 12629548,12629548,12629548,16039587 0415,0018,0004,0018 LC UBE2K RBCK1 19549727 0018 HT UBE2N RBCK1 19549727,19549727,25260751 0397,0018,0997 HT,LC UBE2G1 RBCK1 19549727,19549727 0397,0018 HT UBA52 RBCK1 21455181,21455181 0065,0096 LC UBE2L3 RBCK1 19549727,19549727 0397,0018 HT MAP3K1 RBCK1 25260751 0415 LC UBE2V1 RBCK1 25260751 0997 LC TRIM25 RBCK1 21292167,21292167,21292167,21292167 0415,0096,0428,0004 LC UBE2S RBCK1 19549727,19549727 0397,0018 HT PAN2 RBCK1 23105109 0018 LC UBE2U RBCK1 19549727,19549727 0397,0018 HT TRIM65 RBCK1 22493164,22493164 0018,0397 HT USP49 RBCK1 23105109 0018 LC OTUD6A RBCK1 23105109 0018 LC SYCE1 RBCK1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT TRIML1 RBCK1 22493164,22493164 0018,0397 HT USP32 RBCK1 23105109 0018 LC USP7 RBCK1 23105109 0018 LC OTUB2 RBCK1 23105109 0018 LC RNF31 RBCK1 17006537,22430200,22430200,22791023,17006537,22791023,17006537,22430200,22430200,17006537,22430200,22430200,22430200,17006537 0401,0071,0004,0065,0071,0096,0096,0114,0107,0004,0007,0096,0077,0007 LC TSSK3 RBCK1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT UHRF2 RBCK1 22493164,22493164 0018,0397 HT NDUFAF3 RBCK1 25416956,25416956,25416956 1112,0397,1356 HT RBCK1 RBCK1 25416956,18303026,25416956 0397,0415,0018 HT,LC RBCK1 MKRN2 22493164,22493164 0018,0397 HT RBCK1 ARNT2 24722188 0018 HT RBCK1 SMURF1 20804422 0415 LC RBCK1 RNF181 22493164,22493164 0018,0397 HT RBCK1 MALT1 26525107 0415 LC RBCK1 FKBPL 23912458,23912458 0004,0018 LC RBCK1 USP21 23105109 0018 LC RBCK1 UBE2D4 19549727,19549727 0397,0018 HT RBCK1 DKFZP564J0123 25416956 0018 HT RBCK1 USP15 23105109 0018 LC RBCK1 UCHL5 23105109 0018 LC RBCK1 IKBKG 20098747,20098747,19675569 0096,0089,0415 LC RBCK1 HEL-S-71 19549727 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9BYM8 O14867 RBCK1 BACH1 0.569 17682061 Q9BYM8 P61086 RBCK1 UBE2K 0.183 19549727 Q9BYM8 O15165 RBCK1 LDLRAD4 0.126 26186194 Q9HBZ2 Q9BYM8 ARNT2 RBCK1 0.183 24722188 Q9HCE7 Q9BYM8 SMURF1 RBCK1 0.183 20804422 Q9BYM8 O60260 RBCK1 PARK2 0.183 24722188 Q9BYM8 Q8NFA0 RBCK1 USP32 0.183 23105109 Q9Y4E8 Q9BYM8 USP15 RBCK1 0.183 23105109 Q9Y5K5 Q9BYM8 UCHL5 RBCK1 0.183 23105109 Q9BYM8 O75604 RBCK1 USP2 0.183 23105109 Q9BYM8 Q70CQ1 RBCK1 USP49 0.183 23105109 Q9BYM8 Q7CHB5 RBCK1 Q7CHB5 0.126 20711500 Q9BYM8 P0CG48 RBCK1 UBC 0.902 18303026,17006537,20005846,22139374,19796170 Q9BYM8 Q7L8S5 RBCK1 OTUD6A 0.183 23105109 Q9BYM8 P09022 RBCK1 HOXA1 0.376 23088713 Q9BYM8 O95786 RBCK1 DDX58 0.21 21292167 Q9BYM8 Q8N0S2 RBCK1 SYCE1 0.454 25416956 Q9R0Q3 Q9BYM8 TMED2 RBCK1 0.236 26496610 Q9BYM8 Q8TBB1 RBCK1 LNX1 0.236 unassigned1304 Q9BYM8 Q96PN8 RBCK1 TSSK3 0.583 25416956,unassigned1304 Q9BYM8 P09055 RBCK1 ITGB1 0.236 26496610 Q9BYM8 Q96IQ9 RBCK1 ZNF414 0.236 unassigned1304 Q9BYM8 Q99JP4 RBCK1 CDC26 0.236 26496610 Q9BYM8 Q14258 RBCK1 TRIM25 0.671 21292167 Q9BYM8 P05771 RBCK1 PRKCB 0.731 17069764,17121852,18303026,23042805 Q9BYM8 O75469 RBCK1 NR1I2 0.702 23160820 Q9BYM8 Q02930 RBCK1 CREB5 0.236 unassigned1304 Q9BYM8 P31273 RBCK1 HOXC8 0.236 unassigned1304 Q9BYM8 P61088 RBCK1 UBE2N 0.396 19549727,25260751 Q9Y6K9 Q9BYM8 IKBKG RBCK1 0.911 23032186,20098747,21455180,21811235,21709223,23732909,19675569 Q9BYM8 Q6PJ69 RBCK1 TRIM65 0.286 22493164 Q9BYM8 Q63ZY3 RBCK1 KANK2 0.236 unassigned1304 Q9BYM8 Q8N9V2 RBCK1 TRIML1 0.286 22493164 Q9BYM8 Q8IVS8 RBCK1 GLYCTK 0.236 unassigned1304 Q9P0P0 Q9BYM8 RNF181 RBCK1 0.286 22493164 Q9BYM8 Q96PU4 RBCK1 UHRF2 0.286 22493164 Q9H000 Q9BYM8 MKRN2 RBCK1 0.286 22493164 Q9H0I2 Q9BYM8 ENKD1 RBCK1 0.236 unassigned1304 Q9BYM8 Q13489 RBCK1 BIRC3 0.236 23524849 Q9BYM8 P83887 RBCK1 TUBG1 0.236 26496610 Q9BYM8 Q3UX61 RBCK1 NAA11 0.236 26496610 Q9BYM8 H0YKB7 RBCK1 IL16 {ECO:0000313|ENSEMBL:ENSP00000452738} 0.236 unassigned1304 Q9BYM8 Q5W5X9 RBCK1 TTC23 0.236 unassigned1304 Q9BYM8 P48200 RBCK1 IREB2 0.765 12629548,17822790 Q9BYM8 P25786 RBCK1 PSMA1 0.236 unassigned1304 Q9BYM8 Q7TSY8 RBCK1 SGOL2 0.236 26496610 Q9BYM8 O55187 RBCK1 CBX4 0.236 26496610 Q9BYM8 P55036 RBCK1 PSMD4 0.454 19796170,22517668 Q9BYM8 O60336 RBCK1 MAPKBP1 0.236 unassigned1304 Q9BYM8 P68036 RBCK1 UBE2L3 0.772 19549727,unassigned1304,17006537,18303026 Q9BYM8 Q13077 RBCK1 TRAF1 0.436 21903422,25996949 Q9BYM8 P03372 RBCK1 ESR1 0.814 23912458,23042805 Q9HC29 Q9BYM8 NOD2 RBCK1 0.507 26670046,22607974,23818254 Q9BYM8 P21580 RBCK1 TNFAIP3 0.49 23105109,23032186 Q9BYM8 P61077 RBCK1 UBE2D3 0.772 17682061,12629548,17006537,21292167 Q9BYM8 Q9BYM8 RBCK1 RBCK1 0.659 25416956,16083853,18303026 Q9H0F6 Q9BYM8 SHARPIN RBCK1 0.61 26670046,23032186,24726327 Q9BYM8 Q96BN8 RBCK1 OTULIN 0.61 26670046,23708998,24726327,24726323 Q9BYM8 P01375 RBCK1 TNF 0.757 26670046,23032186,25911380,20005846 Q9BYM8 Q96EP0 RBCK1 RNF31 1 26670046,17006537,20005846,26525107,22430200,26577923,17069764,23708998,22791023,24726327,23032187 Q9BYM8 P36941 RBCK1 LTBR 0.126 26186194 Q9BYM8 Q93009 RBCK1 USP7 0.183 23105109 Q9BYM8 P35227 RBCK1 PCGF2 0.286 22493164 Q9BYM8 Q8XC86 RBCK1 ESPB {ECO:0000313|EMBL:AAG58818.1} 0.183 25519916 Q9BYM8 Q96DC9 RBCK1 OTUB2 0.183 23105109 Q9BYM8 Q921I0 RBCK1 ORMDL1 0.126 26496610 Q9BYM8 Q9BU61 RBCK1 NDUFAF3 0.523 25416956 Q9BYM8 B3KSH4 RBCK1 HIP2 0.236 19549727 Q9BYM8 O14933 RBCK1 UBE2L6 0.702 19549727,25416956,unassigned1304 Q9BYM8 O43318 RBCK1 MAP3K7 0.21 17449468 Q9BYM8 P05067 RBCK1 APP 0.183 21832049 Q9BYM8 P07900 RBCK1 HSP90AA1 0.376 23912458 Q9BYM8 P0CK53 RBCK1 P0CK53 0.183 17446270 Q9BYM8 P17252 RBCK1 PRKCA 0.454 25118570 Q9BYM8 P19474 RBCK1 TRIM21 0.286 22493164 Q9BYM8 P22314 RBCK1 UBA1 0.033 25260751 Q9BYM8 P29590 RBCK1 PML 0.126 15833741 Q9BYM8 P41227 RBCK1 NAA10 0.454 25416956 Q9BYM8 P49116 RBCK1 NR2C2 0.21 17449468 Q9BYM8 P51668 RBCK1 UBE2D1 0.309 17006537 Q9BYM8 P62253 RBCK1 UBE2G1 0.376 19549727 Q9BYM8 P62837 RBCK1 UBE2D2 0.309 17006537 Q9BYM8 Q13404 RBCK1 UBE2V1 0.033 25260751 Q9BYM8 Q13546 RBCK1 RIPK1 0.21 17449468 Q9BYM8 Q16763 RBCK1 UBE2S 0.376 19549727 Q9BYM8 Q4VA12 RBCK1 TRAF1 0.236 21903422 Q9BYM8 Q5VVX9 RBCK1 UBE2U 0.286 19549727 Q9BYM8 Q62925 RBCK1 MAP3K1 0.033 25260751 Q9BYM8 Q8N5C8 RBCK1 TAB3 0.21 17449468 Q9JLY0 Q9BYM8 SOCS6 RBCK1 0.787 16643902 Q9NYJ8 Q9BYM8 TAB2 RBCK1 0.376 17449468 Q9UIM3 Q9BYM8 FKBPL RBCK1 0.569 23912458 Q9Y2X8 Q9BYM8 UBE2D4 RBCK1 0.376 19549727 Q9Y4K3 Q9BYM8 TRAF6 RBCK1 0.21 17449468 Q9CQZ0 Q9BYM8 ORMDL2 RBCK1 0.126 26496610 Q9UDY8 Q9BYM8 MALT1 RBCK1 0.309 26525107 Q9UK80 Q9BYM8 USP21 RBCK1 0.183 23105109 Q9BYM8 P46934 RBCK1 NEDD4 0.183 19953087 Q9BYM8 Q13233 RBCK1 MAP3K1 0.183 25260751 Q9BYM8 Q504Q3 RBCK1 PAN2 0.183 23105109

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 EYA2 RBCK1 MI:0362 inference MI:0461 interaction database CBX4 RBCK1 MI:0362 inference MI:0461 interaction database SOCS6 RBCK1 MI:0362 inference MI:0461 interaction database BACH1 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database IKBKB RBCK1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database UBE2L6 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database CHUK RBCK1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database LDLRAD4 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database SIAH2 RBCK1 MI:0362 inference MI:1106 pathways database MAP3K7 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database PARK2 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database NR1I2 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database USP2 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database FBXO21 RBCK1 MI:0362 inference MI:1106 pathways database DDX58 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database TNF RBCK1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ESR1 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database APP RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database ITGB1 RBCK1 MI:0362 inference MI:0461 interaction database PRKCB RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AA1 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database UBB RBCK1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database UBC RBCK1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PRKCA RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database TNFRSF1A RBCK1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database TRIM21 RBCK1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TNFAIP3 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database UBA1 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database TUBG1 RBCK1 MI:0362 inference MI:0461 interaction database PCGF2 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database LTBR RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database CCNF RBCK1 MI:0362 inference MI:1106 pathways database NAA10 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database NEDD4 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database IREB2 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database NR2C2 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2A RBCK1 MI:0362 inference MI:1106 pathways database HOXA1 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D1 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database PSMD4 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database FBXW4 RBCK1 MI:0362 inference MI:1106 pathways database UBE2D3 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2K RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2N RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2G1 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D2 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database RBX1 RBCK1 MI:0362 inference MI:1106 pathways database RPS27A RBCK1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database UBA52 RBCK1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database SKP1 RBCK1 MI:0362 inference MI:1106 pathways database UBE2L3 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database PRKCZ RBCK1 MI:0362 inference MI:0461 interaction database TRAF2 RBCK1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database TRAF1 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database FADD RBCK1 MI:0362 inference MI:0461 interaction database MAP3K1 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database SKP2 RBCK1 MI:0362 inference MI:1106 pathways database UBE2V1 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database BIRC3 RBCK1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database BIRC2 RBCK1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database RIPK1 RBCK1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database CUL1 RBCK1 MI:0362 inference MI:1106 pathways database TRIM25 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database TRIP12 RBCK1 MI:0362 inference MI:1106 pathways database CASP8 RBCK1 MI:0362 inference MI:0461 interaction database TMED2 RBCK1 MI:0362 inference MI:0461 interaction database TRADD RBCK1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database UBE2S RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database LONRF1 RBCK1 MI:0362 inference MI:1106 pathways database PAN2 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database ORMDL2 RBCK1 MI:0362 inference MI:0461 interaction database SGO2 RBCK1 MI:0362 inference MI:0461 interaction database HECTD2 RBCK1 MI:0362 inference MI:1106 pathways database UBE2U RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database FBXO31 RBCK1 MI:0362 inference MI:1106 pathways database FBXW9 RBCK1 MI:0362 inference MI:1106 pathways database FBXW10 RBCK1 MI:0362 inference MI:1106 pathways database RNF213 RBCK1 MI:0362 inference MI:1106 pathways database FBXL22 RBCK1 MI:0362 inference MI:1106 pathways database FBXL19 RBCK1 MI:0362 inference MI:1106 pathways database TRIM65 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database FBXW12 RBCK1 MI:0362 inference MI:1106 pathways database RNF19B RBCK1 MI:0362 inference MI:1106 pathways database USP49 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database OTUD6A RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database RNF144B RBCK1 MI:0362 inference MI:1106 pathways database RBBP6 RBCK1 MI:0362 inference MI:1106 pathways database HUWE1 RBCK1 MI:0362 inference MI:1106 pathways database TRIM69 RBCK1 MI:0362 inference MI:1106 pathways database SIAH1 RBCK1 MI:0362 inference MI:1106 pathways database HERC6 RBCK1 MI:0362 inference MI:1106 pathways database UBR2 RBCK1 MI:0362 inference MI:1106 pathways database SYCE1 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database FBXL14 RBCK1 MI:0362 inference MI:1106 pathways database FBXW8 RBCK1 MI:0362 inference MI:1106 pathways database FBXL16 RBCK1 MI:0362 inference MI:1106 pathways database TAB3 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database TRIML1 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database FBXO15 RBCK1 MI:0362 inference MI:1106 pathways database ZNRF1 RBCK1 MI:0362 inference MI:1106 pathways database FBXL13 RBCK1 MI:0362 inference MI:1106 pathways database FBXO22 RBCK1 MI:0362 inference MI:1106 pathways database USP32 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database ZNRF2 RBCK1 MI:0362 inference MI:1106 pathways database CDC26 RBCK1 MI:0362 inference MI:0461 interaction database FBXO27 RBCK1 MI:0362 inference MI:1106 pathways database FBXO30 RBCK1 MI:0362 inference MI:1106 pathways database RNF217 RBCK1 MI:0362 inference MI:1106 pathways database DTX3L RBCK1 MI:0362 inference MI:1106 pathways database FBXO41 RBCK1 MI:0362 inference MI:1106 pathways database LMO7 RBCK1 MI:0362 inference MI:1106 pathways database MYLIP RBCK1 MI:0362 inference MI:1106 pathways database CREBBP RBCK1 MI:0362 inference MI:0461 interaction database USP7 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database FBXW7 RBCK1 MI:0362 inference MI:1106 pathways database FBXO32 RBCK1 MI:0362 inference MI:1106 pathways database FBXW5 RBCK1 MI:0362 inference MI:1106 pathways database MIB2 RBCK1 MI:0362 inference MI:1106 pathways database SPSB1 RBCK1 MI:0362 inference MI:1106 pathways database OTULIN RBCK1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database FBXL8 RBCK1 MI:0362 inference MI:1106 pathways database OTUB2 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database FBXO17 RBCK1 MI:0362 inference MI:1106 pathways database RNF31 RBCK1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database FBXL20 RBCK1 MI:0362 inference MI:1106 pathways database FBXL18 RBCK1 MI:0362 inference MI:1106 pathways database TSSK3 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database UHRF2 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database NEDD4L RBCK1 MI:0362 inference MI:1106 pathways database EYA1 RBCK1 MI:0362 inference MI:0461 interaction database NAA11 RBCK1 MI:0362 inference MI:0461 interaction database NDUFAF3 RBCK1 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 MKRN2 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 SHARPIN MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database RBCK1 FBXL15 MI:0362 inference MI:1106 pathways database RBCK1 FBXO44 MI:0362 inference MI:1106 pathways database RBCK1 UNKL MI:0362 inference MI:1106 pathways database RBCK1 SMURF2 MI:0362 inference MI:1106 pathways database RBCK1 ARNT2 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 NOD2 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 TRIM36 MI:0362 inference MI:1106 pathways database RBCK1 FBXO6 MI:0362 inference MI:1106 pathways database RBCK1 TUBG2 MI:0362 inference MI:0461 interaction database RBCK1 RNF19A MI:0362 inference MI:1106 pathways database RBCK1 RLIM MI:0362 inference MI:1106 pathways database RBCK1 FBXL12 MI:0362 inference MI:1106 pathways database RBCK1 TAB2 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 RNF181 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 ORMDL1 MI:0362 inference MI:0461 interaction database RBCK1 MALT1 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 FBXO40 MI:0362 inference MI:1106 pathways database RBCK1 HERC5 MI:0362 inference MI:1106 pathways database RBCK1 FKBPL MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 FBXL7 MI:0362 inference MI:1106 pathways database RBCK1 FBXO2 MI:0362 inference MI:1106 pathways database RBCK1 USP21 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 FBXO10 MI:0362 inference MI:1106 pathways database RBCK1 FBXO9 MI:0362 inference MI:1106 pathways database RBCK1 FBXL5 MI:0362 inference MI:1106 pathways database RBCK1 FBXL4 MI:0362 inference MI:1106 pathways database RBCK1 FBXW11 MI:0362 inference MI:1106 pathways database RBCK1 FBXO4 MI:0362 inference MI:1106 pathways database RBCK1 FBXL21 MI:0362 inference MI:1106 pathways database RBCK1 FBXL3 MI:0362 inference MI:1106 pathways database RBCK1 FBXW2 MI:0362 inference MI:1106 pathways database RBCK1 BTRC MI:0362 inference MI:1106 pathways database RBCK1 UBE2D4 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 FBXO7 MI:0362 inference MI:1106 pathways database RBCK1 USP15 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 TRAF6 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 RNF115 MI:0362 inference MI:1106 pathways database RBCK1 RNF114 MI:0362 inference MI:1106 pathways database RBCK1 UCHL5 MI:0045 experimental interaction detection MI:0461 interaction database RBCK1 WSB1 MI:0362 inference MI:1106 pathways database RBCK1 IKBKG MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database