PTM - CPLM Gene Name UniProt ID Type Position Code KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 101 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 1121 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 40 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 776 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 370 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 377 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 1023 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 307 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 459 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 682 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 235 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 1092 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 91 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 657 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 1114 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 996 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 205 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 45 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 1442 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 82 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 935 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 550 K KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 Ubiquitination 687 K

PTM - dbPAF Gene Name UniProt ID Position Type Species KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 1257 T Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 1327 Y Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 1333 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 1340 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 1356 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 1358 T Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 1359 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 1484 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 1485 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 239 Y Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 285 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 287 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 299 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 301 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 317 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 553 T Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 751 Y Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 799 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 849 T Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 896 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 897 S Homo sapiens(Human) KDM5C; DXS1272E; JARID1C; SMCX; XE169 P41229 946 T Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA P41229 K205-ac Acetylation RQSVQPSkFNSYGRR P41229 K1087-ac Acetylation SWREKASkTFLKKNS P41229 K1241-ac Acetylation AWWEWDTkFLCPLCM P41229 T66-p Phosphorylation EVDNFRFtPRIQRLN P41229 Y239-p Phosphorylation ELKKLQIyGAGPKMM P41229 S287-p Phosphorylation DVKVESTsPkTFLES P41229 S299-p Phosphorylation LESKEELsHsPEPCt P41229 S301-p Phosphorylation SKEELsHsPEPCtKM P41229 T306-p Phosphorylation sHsPEPCtKMTMRLR P41229 S317-p Phosphorylation MRLRRNHsNAQFIES P41229 S799-p Phosphorylation EELRALEsEARERRF P41229 T849-p Phosphorylation RVAGLQMtLTELRAF P41229 S897-p Phosphorylation ALASLPSsPGLLQSL P41229 T946-p Phosphorylation APSARRGtLAVMRGL P41229 T1257-p Phosphorylation SRRPRLEtILALLVA P41229 Y1327-p Phosphorylation RPEEPPNyPAAPAsD P41229 S1333-p Phosphorylation NyPAAPAsDPLREGs P41229 S1340-p Phosphorylation sDPLREGsGKDMPKV P41229 S1356-p Phosphorylation GLLENGDsVtsPEKV P41229 T1358-p Phosphorylation LENGDsVtsPEKVAP P41229 S1359-p Phosphorylation ENGDsVtsPEKVAPE P41229 K33-sm Sumoylation DPLGYIAkIRPIAEK P41229 K191-sm Sumoylation EEKDKEYkPHSIPLR P41229 K91-ub Ubiquitination NYLDQIAkFWEIQGS P41229 K101-ub Ubiquitination EIQGSSLkIPNVERR P41229 K289-ub Ubiquitination KVESTsPkTFLESKE P41229 K459-ub Ubiquitination GFPVSDSkRHLTPEE P41229 K1121-ub Ubiquitination KRSRWMEkELGLYKS P41229 K1151-ub Ubiquitination GSVIVAFkEGEQkEK P41229 K1156-ub Ubiquitination AFkEGEQkEKEGILQ

PTM - dbPTM UniProt ID Position Code Type Resources References P41229 317 S Phosphorylation Swiss-Prot 1010711 17081983;18669648 P41229 1359 S Phosphorylation Swiss-Prot 1010711 15302935;16964243;19690332 P41229 317 S Phosphorylation PhosphoELM.10011 18669648;17081983 P41229 897 S Phosphorylation PhosphoELM.10011 18669648 P41229 1359 S Phosphorylation PhosphoELM.10011 16964243;15302935 P41229 1121 K Ubiquitylation Phosphositeplus.1010730 21890473 P41229 1356 S Phosphorylation Phosphositeplus.1010730 19664994 P41229 1359 S Phosphorylation Phosphositeplus.1010730 15302935;16964243;19664994;19690332;20068231;21406692;22115753 P41229 317 S Phosphorylation Phosphositeplus.1010730 18669648;20363803 P41229 1358 T Phosphorylation Phosphositeplus.1010730 19690332;21659604 P41229 301 S Phosphorylation HPRD 9.0 18767875 P41229 317 S Phosphorylation HPRD 9.0 17081983,18669648,19651622,20068231 P41229 896 S Phosphorylation HPRD 9.0 20068231 P41229 897 S Phosphorylation HPRD 9.0 18669648 P41229 1356 S Phosphorylation HPRD 9.0 19664994 P41229 1359 S Phosphorylation HPRD 9.0 17322306,19413330,19651622,19664994,16964243,18767875,18452278,20068231 P41229 1358 T Phosphorylation HPRD 9.0 19651622 P41229 317 S Phosphorylation SysPTM 1.1 17081983;18669648 P41229 1359 S Phosphorylation SysPTM 1.1 15302935;16964243

PTM - HPRD Symbol Position Code Type References KDM5C 1356 S Phosphorylation 19664994 KDM5C 1358 T Phosphorylation 19651622 KDM5C 1359 S Phosphorylation 17322306,19413330,19651622,19664994,16964243,18767875,18452278,20068231 KDM5C 301 S Phosphorylation 18767875 KDM5C 317 S Phosphorylation 17081983,18669648,19651622,20068231 KDM5C 896 S Phosphorylation 20068231 KDM5C 897 S Phosphorylation 18669648

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type P41229 897 S 18669648 HTP Phosphorylation P41229 317 S 18669648 HTP Phosphorylation P41229 317 S 17081983 HTP Phosphorylation P41229 1359 S 16964243 HTP Phosphorylation P41229 1359 S 15302935 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs P41229 287 Phosphoserine 23186163 P41229 301 Phosphoserine 23186163 P41229 317 Phosphoserine 18669648;23186163 P41229 897 Phosphoserine 23186163 P41229 1359 Phosphoserine 16964243;19690332;20068231;21406692;23186163

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 8242 113870 - K Ubiquitination 21139048 8242 113870 - K Ubiquitination 21890473 8242 113870 - K Sumoylation 21252943 8242 113870 - K Ubiquitination 21963094

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID KDM5C Homo sapiens (Human) 101; 1120 "101,IQGSSLKIPNVER; 1120,RSRWMEKELGLYK" 101:21890473; 1120:21890473 KDM5C Homo sapiens (Human) 1080 "1080,RSRWMEKELGLYK" 1080:21890473 KDM5C Homo sapiens (Human) 1080 "1080,RSRWMEKELGLYK" 1080:21890473 KDM5C Homo sapiens (Human) 101; 1121 "101,IQGSSLKIPNVER; 1121,RSRWMEKELGLYK" 101:21890473; 1121:21890473 KDM5C Homo sapiens (Human) 101; 1121 "101,IQGSSLKIPNVER; 1121,RSRWMEKELGLYK" 101:21890473; 1121:21890473 KDM5C Homo sapiens (Human) 101; 1121 "101,IQGSSLKIPNVER; 1121,RSRWMEKELGLYK" 101:21890473; 1121:21890473