PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus PRPF4 EPS15L1 22863883 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PRKCDBP EPS15L1 19262564 mint,intact exp G G G G G GP G G GP G G G G G G G GP GP G G GP G G G G G G G G NCAPG EPS15L1 22863883 biogrid exp P G GP P GP GP P P P GP G GP P P GP P P G G GP GP GP G EPS15L1 KIAA1107 26496610 biogrid,intact exp GP GP G P GP G P GP G P P P P G P GP GP P G P GP GP GP P P P GP G BIRC6 EPS15L1 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DVL2 EPS15L1 20007894 i2d exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G VCAM1 EPS15L1 22623428 intact exp G G G G G G G G G G GP G G GP G G G G G G G G G G G GP G GP G PLK1 EPS15L1 26496610 biogrid,intact exp P P G G GP P G GP GP P P P GP GP GP GP GP G GP P GP GP GP P P GP MED4 EPS15L1 25281560 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G XPO1 EPS15L1 26673895 biogrid exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EPS15L1 UBQLN1 16159959 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TRAPPC2 EPS15L1 25416956 intact exp P P P P P P P P P P P P P P P P P P P P P NTRK1 EPS15L1 25921289 biogrid exp P P P G P P P P P P P P P P P P P P P ZZEF1 EPS15L1 22863883 biogrid exp G GP G G G G G G GP G G G G G G GP G G G G GP G G G GP G GP GP G EPS15L1 NXF1 22658674 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SPC25 EPS15L1 26186194 biogrid exp P G GP P P P GP P GP P P P MOV10 EPS15L1 22658674 biogrid exp G G G G G G G G G G G G G G G G G G G G G G GNG5 EPS15L1 25416956 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ESR2 EPS15L1 21182203 intact exp GP GP G GP GP G GP GP GP GP GP GP G P GP GP GP G GP P GP GP GP GP GP GP RAC1 EPS15L1 20936779 i2d exp GP GP G G GP G G G GP G G G GP G G GP G G GP G GP GP G GP GP G GP GP G EPS15L1 EPN1 9723620, 25402006 hprd,biogrid exp, ortho, pred GP GP G G G GP G G GP G GP G G GP G GP GP G GP G GP GP GP GP GP G GP GP G ITSN1 EPS15L1 22558309,26344197, 25402006 biogrid exp, ortho, pred G GP G G G GP G GP GP G GP GP GP GP G GP GP G G G GP G GP GP GP G GP GP G STON2 EPS15L1 18200045,11381094, 25402006, 21836163 hprd,biogrid,mint,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NUMB EPS15L1 23211419, 21836163 intact exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP GP GP GP G GBF1 EPS15L1 22863883, 23023127 biogrid exp, pred GP GP G G G GP G GP GP G GP G G GP G GP GP GP GP G GP GP GP GP GP G G GP G ITSN2 EPS15L1 22558309,26344197,20007894,20697350, 25402006, 23023127 biogrid,i2d exp, pred G G G G G GP G G GP G GP GP G G G GP GP G GP G GP GP G G GP G GP GP G AGFG2 EPS15L1 9303539, 21836163 hprd exp, pred GP GP G G GP GP G G G G G G G G G G GP G G G G G GP G G G G G G AGFG1 EPS15L1 10613896, 21836163 hprd exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP G G GP GP GP GP G GRB2 EPS15L1 21706016, 25402006 biogrid,intact exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G AP2M1 EPS15L1 26186194,24189400, 25402006 biogrid,intact exp, pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP G G G GP G GP GP G EPS15L1 EPS15L1 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PEX13 EPS15L1 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G YWHAE EPS15L1 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CYCS EPS15L1 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ORC4 EPS15L1 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G AP1B1 EPS15L1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RPS27A EPS15L1 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SH3GL3 EPS15L1 ortho G G G G GP G G G G G G G G G GP G GP G G G G G G GP GP G UBC EPS15L1 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CLTC EPS15L1 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G CDKL1 EPS15L1 ortho P P P G P P P G P P P P P G G OSTF1 EPS15L1 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP G GP GP GP GP GP G EPS15L1 ARHGAP26 ortho GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP G GP GP G RASGEF1B EPS15L1 ortho P P P P G P P P P P P P P P EED EPS15L1 ortho GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G SLC2A4 EPS15L1 ortho P P P P P P P P P P P CSK EPS15L1 ortho G G G G GP GP G G GP G G G GP GP G GP GP G GP G GP G G G GP GP GP GP G EPS15 EPS15L1 25402006 ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DAB2 EPS15L1 21836163 ortho, pred G GP G G G G G G G G GP G GP G G G G G G G GP G G G G G G G G AP2A2 EPS15L1 25402006 ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G STAM EPS15L1 25402006, 21836163 ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP G GP GP G HGS EPS15L1 25402006 ortho, pred GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP GP GP G GP GP G YWHAB EPS15L1 25402006 ortho, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G AP2A1 EPS15L1 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G KRT35 EPS15L1 21836163 pred G REPS1 EPS15L1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G REPS2 EPS15L1 25402006 pred G G G G GP GP G GP G GP GP GP GP GP GP GP GP G GP GP G P GP P GP P KCNIP2 EPS15L1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G STAM2 EPS15L1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HMHA1 EPS15L1 21836163 pred G G G GP P G P G G GP G G P GP G GP G SEC24A EPS15L1 21836163 pred G GP G G G G G G GP G GP GP GP GP G GP G G GP G GP GP GP G GP GP GP GP G CDC42 EPS15L1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MYO1G EPS15L1 21836163 pred G GP G G GP GP G G GP G GP G GP GP G G GP G G G GP G G G G GP GP GP G VAMP7 EPS15L1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G RFWD2 EPS15L1 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G PPAP2A EPS15L1 21836163 pred G G G G G GP G G GP G GP G G G G GP GP G GP G G GP G G GP G GP G G MIB1 EPS15L1 23023127 pred GP GP G G GP GP G G GP G GP GP G GP G GP GP GP GP G GP GP GP G GP G GP GP G CALN1 EPS15L1 23023127 pred P GP G P GP P P G P P G P GP P P P P P P P P EPS15L1 STON1 25402006 pred G GP GP G GP GP G GP G GP G G GP GP GP G G GP GP G GP GP G GP P G SYT1 EPS15L1 25402006 pred G G G G G GP G G G G G G G G G G GP G G G G G G G G G G G G EPN3 EPS15L1 25402006 pred GP P P G G GP GP P P GP P GP P GP GP GP P GP P ARF4 EPS15L1 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SHC3 EPS15L1 25402006 pred P GP G GP P GP G P P P G P GP P P P P GP P GP P P ALF EPS15L1 21836163 pred HIP1R EPS15L1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G CBL EPS15L1 21836163 pred G GP G G GP GP G G GP G GP G GP GP G G GP GP G G G G G G G GP G GP G SLC2A8 EPS15L1 21836163 pred GP G G G P G G GP P G G G G G G G G G G GP G MAP4K3 EPS15L1 21836163 pred G G G P GP G G GP G GP G GP GP G GP GP G GP G GP G G GP GP G GP GP G PICALM EPS15L1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G COPA EPS15L1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G SYT11 EPS15L1 21836163 pred GP GP G G G GP G G GP G GP G G G G GP GP G G G G G G GP G G G G SNAP91 EPS15L1 21836163 pred G GP G P G GP G G G G RAB1B EPS15L1 21836163 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G EPN2 EPS15L1 25402006 pred P P P P P P P STAB2 EPS15L1 21836163 pred GP GP G G G GP G GP GP G G GP G G P GP G G GP GP G P G GP G G EGFR EPS15L1 25402006 pred GP GP G GP G G GP G GP GP G G G GP GP G G G GP GP G GP GP G GP GP G GAK EPS15L1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G S100A9 EPS15L1 23023127 pred GP G G GP G G G G GP GP G G G G G GP G G G GP G G AP2B1 EPS15L1 21836163 pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G EPS15L1 GGA1 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9UBC2 A0A024R284 two hybrid 16159959 direct interaction X 2 Q9UBC2 A0A024R284 affinity chromatography technology 16159959 physical association X 2 Q9UBC2 P52594-3 two hybrid 10613896 direct interaction X 2 Q9UBC2 A6H8W8 affinity chromatography technology 20697350 physical association X 2 Q9UBC2 biochemical 22863883 colocalization X 2 Q9UBC2 Q9BPX3 biochemical 22863883 colocalization X 2 Q9UBC2 O43149 biochemical 22863883 colocalization X 2 Q9UBC2 Q9D0F1 affinity chromatography technology 20360068 physical association X 2 Q9UBC2 Q6PD56 two hybrid 22558309 direct interaction X 2 Q9UBC2 A6H8W8 two hybrid 22558309 direct interaction X 2 Q9NR09 Q9UBC2 biochemical 22863883 colocalization X 2 Q9UBC2 P0CG48 affinity chromatography technology 22505724 physical association X 2 Q9UBC2 P62993-2 affinity chromatography technology 21706016 physical association X 2 Q9UBC2 P0CG48 affinity chromatography technology 21963094 physical association X 2 Q9UBC2 P0CG48 affinity chromatography technology 23000965 physical association X 2 Q9UBC2 O43172-2 biochemical 22863883 colocalization X 2 Q9UBC2 P0CG48 affinity chromatography technology 24654937 physical association X 2 Q9UBC2 P0CG48 affinity chromatography technology 24816145 physical association X 2 Q9UBC2 P0CG48 affinity chromatography technology 25147182 physical association X 2 Q9UBC2 P63218 two hybrid 25416956 direct interaction X 2 Q9UBC2 Q8WXE9 two hybrid 11381094 direct interaction X 2 Q9UBC2 Q9Y6I3-1 affinity chromatography technology 9723620 physical association X 2 Q9UBC2 P0CG48 affinity chromatography technology 12072436 physical association X 2 Q9UBC2 Q9CQU5 affinity chromatography technology 20360068 physical association X 2 Q9UBC2 P0CG48 affinity chromatography technology 21987572 physical association X 2 Q9UBC2 P0CG48 affinity chromatography technology 21139048 physical association X 2 Q9UBC2 P0CG48 affinity chromatography technology 21890473 physical association X 2 Q9UBC2 P0CG48 affinity chromatography technology 21906983 physical association X 2 Q3UQN2 Q9UBC2 affinity chromatography technology 20448150 physical association X 2 Q9UBC2 P52594-2 in vivo 10613896 - X 2 Q9UBC2 P52594-2 two hybrid 10613896 - X 2 Q9UBC2 P52594-2 two hybrid 10613896 - X 2 Q9UBC2 P52594-2 in vivo 10613896 - X 2 A4D2D6 Q9UBC2 in vitro 9303539 - X 2 A4D2D6 Q9UBC2 in vitro 9303539 - X 2 Q9Y6I3-3 Q9UBC2 in vitro 9723620 - X 2 Q9Y6I3-3 Q9UBC2 in vitro 9723620 - X 2 Q9UBC2 Q8WXE9 two hybrid 11381094 - X 2 Q9UBC2 Q8WXE9 two hybrid 11381094 - X 2 Q9UBC2 anti tag coimmunoprecipitation 19262564 association C 3 Q9UBC2 cross-linking study 22623428 association C 183 Q9UBC2 tandem affinity purification 24189400 association C 24 Q9UBC2 cosedimentation through density gradient 21182203 association C 141 Q9UBC2 tandem affinity purification 20360068 physical association C 35 Q9UBC2 anti tag coimmunoprecipitation 23211419 association C 19 Q9UBC2 anti tag coimmunoprecipitation 23211419 association C 17 Q9UBC2 anti bait coimmunoprecipitation 23211419 association C 12 Q9UBC2 anti bait coimmunoprecipitation 23211419 association C 12 Q9UBC2 Q81Y46 two hybrid pooling approach 20711500 physical association X 2 Q9UBC2 P0DI81 two hybrid prey pooling approach 25416956 physical association X 2 Q9UBC2 P0DI81 two hybrid array 25416956 physical association X 2 Q9UBC2 P0DI81 validated two hybrid 25416956 physical association X 2 Q9UBC2 O88339 far western blotting 9723620 physical association X 2 Q969G5 Q9UBC2 anti tag coimmunoprecipitation 19262564 physical association X 2 Q9UBC2 tandem affinity purification 20360068 physical association C 22 Q9UBC2 pull down 20448150 association C 9 Q9UBC2 anti bait coimmunoprecipitation 23211419 association C 11 Q9UBC2 Q8WXE9 isothermal titration calorimetry 18200045 direct interaction X 2 Q9UBC2 P63218 two hybrid prey pooling approach 25416956 physical association X 2 Q9UBC2 P63218 two hybrid array 25416956 physical association X 2 Q9UBC2 P63218 validated two hybrid 25416956 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBC EPS15L1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12072436,16497223,21139048,21890473,21906983,21963094,21987572,22505724,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_132765|BIOGRID_178350|BIOGRID_163485|BIOGRID_269323|BIOGRID_224738|BIOGRID_172722|BIOGRID_169033|BIOGRID_124704|BIOGRID_265502 prey|bait|bait|bait|bait|bait|bait|bait|bait bait|prey|prey|prey|prey|prey|prey|prey|prey BIRC6 EPS15L1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_298724 prey bait GRB2 EPS15L1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 21706016 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_113996|BIOGRID_257717 bait|bait prey|prey ITSN2 EPS15L1 MI:0018(two hybrid)|MI:0004(affinity chromatography technology) 20697350,22558309 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_185877|BIOGRID_217056 bait|bait prey|prey AGFG1 EPS15L1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0493(in vivo) 10613896 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0799(additive genetic interaction defined by inequality)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_77743|BIOGRID_96164|HPRD_7907 prey|prey|- bait|bait|- ZZEF1 EPS15L1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_305268 prey bait NCAPG EPS15L1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_301314 prey bait PRKCDBP EPS15L1 MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy) 10,19262564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association) MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact) MINT_42199|MINT_72224|UniProt_99856|MINT_42198|MINT_72223|UniProt_99857 bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey PRPF4 EPS15L1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_302307 prey bait ITSN1 EPS15L1 MI:0018(two hybrid) 22558309 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_185818 bait prey AGFG2 EPS15L1 MI:0493(in vivo) 9303539 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_12834 - - EPS15L1 UBQLN1 MI:0018(two hybrid)|MI:0018(two hybrid) 16159959 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_195655|BIOGRID_195654 bait|bait prey|prey STON2 EPS15L1 MI:0416(fluorescence microscopy)|MI:0492(in vitro)|MI:0018(two hybrid)|MI:0416(fluorescence microscopy)|MI:0065(isothermal titration calorimetry) 11381094,18200045 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) MI:0471(mint)|MI:0468(hprd)|(biogrid)|MI:0471(mint)|(intact) MINT_61136|HPRD_15280|BIOGRID_103042|MINT_32288|UniProt_93811 prey|-|bait|prey|prey bait|-|prey|bait|bait NRF1 EPS15L1 MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_294673 bait prey GBF1 EPS15L1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_299676 bait prey EPS15L1 EPN1 MI:0004(affinity chromatography technology)|MI:0493(in vivo) 9723620 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_106954|HPRD_14161 prey|- bait|-

PPI - HINT Gene A Gene B PMID Method Quality ZZEF1 EPS15L1 22863883 0401 HT PRPF4 EPS15L1 22863883 0401 HT UBC EPS15L1 12072436,16497223 0004,0096 LC PLK1 EPS15L1 26496610,26496610,27173435 0007,0004,0676 HT DCAF7 EPS15L1 27173435 0676 HT ITSN1 EPS15L1 26344197 0401 HT GBF1 EPS15L1 22863883 0401 HT AP2M1 EPS15L1 24189400,26186194,24189400 0004,0004,0676 LC,HT NCAPG EPS15L1 22863883 0401 HT SPC25 EPS15L1 26186194 0004 HT BIRC6 EPS15L1 22863883 0401 HT ITSN2 EPS15L1 20697350,26344197 0004,0401 LC,HT EPS15L1 KIAA1107 26496610,26496610 0007,0004 HT ZZEF1 EPS15L1 22863883 0401 HT PRPF4 EPS15L1 22863883 0401 HT PLK1 EPS15L1 26496610,26496610,27173435 0007,0004,0676 HT DCAF7 EPS15L1 27173435 0676 HT ITSN1 EPS15L1 26344197 0401 HT GBF1 EPS15L1 22863883 0401 HT AP2M1 EPS15L1 26186194 0004 HT NCAPG EPS15L1 22863883 0401 HT SPC25 EPS15L1 26186194 0004 HT BIRC6 EPS15L1 22863883 0401 HT ITSN2 EPS15L1 26344197 0401 HT EPS15L1 KIAA1107 26496610,26496610 0007,0004 HT UBC EPS15L1 12072436,16497223 0004,0096 LC AP2M1 EPS15L1 24189400,24189400 0004,0676 LC ITSN2 EPS15L1 20697350 0004 LC ZZEF1 EPS15L1 22863883 0401 LC PRPF4 EPS15L1 22863883 0401 LC TRAPPC2 EPS15L1 25416956,25416956,25416956 1112,0397,1356 HT VCAM1 EPS15L1 22623428 0030 LC AGFG1 EPS15L1 10613896 0018 LC GNG5 EPS15L1 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT ITSN1 EPS15L1 22558309,26344197 0018,0401 HT,LC STON2 EPS15L1 18200045,11381094 0065,0018 LC GBF1 EPS15L1 22863883 0401 LC ESR2 EPS15L1 21182203 0029 HT NCAPG EPS15L1 22863883 0401 LC BIRC6 EPS15L1 22863883 0401 LC ITSN2 EPS15L1 22558309,26344197 0018,0401 HT,LC EPS15L1 UBQLN1 16159959,16159959 0004,0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9UBC2 Q9HBM1 EPS15L1 SPC25 0.126 26186194 Q9UBC2 Q9HCE1 EPS15L1 MOV10 0.126 22658674 Q9UBC2 O60271 EPS15L1 SPAG9 0.126 unassigned1312 Q9UBC2 Q9NPJ6 EPS15L1 MED4 0.126 25281560 Q9Y6I3 Q9UBC2 EPN1 EPS15L1 0.21 9723620 Q9Y6Y0 Q9UBC2 IVNS1ABP EPS15L1 0.126 unassigned1312 Q9Y4E8 Q9UBC2 USP15 EPS15L1 0.126 unassigned1312 Q9UBC2 O88339 EPS15L1 EPN1 0.21 9723620 Q9UBC2 Q6P5F9 EPS15L1 XPO1 0.126 26673895 Q9UBC2 P04629 EPS15L1 NTRK1 0.126 25921289 Q9UBC2 Q9QZS3 EPS15L1 NUMB 0.236 23211419 Q9UMX0 Q9UBC2 UBQLN1 EPS15L1 0.454 16159959 Q9UBC2 F8WE45 EPS15L1 LRRC7 {ECO:0000313|ENSEMBL:ENSP00000394867} 0.236 unassigned1304 Q9UBC2 Q8WXE9 EPS15L1 STON2 0.523 11381094,18200045 Q9UPP5 Q9UBC2 KIAA1107 EPS15L1 0.236 26496610 Q9UBC2 Q969G5 EPS15L1 PRKCDBP 0.376 19262564 Q9UBC2 Q9CQU5 EPS15L1 ZWINT 0.236 20360068 Q9UBC2 Q9D0F1 EPS15L1 NDC80 0.236 20360068 Q9UBC2 A3KGV1 EPS15L1 ODF2 0.236 26496610 Q9UBC2 Q15811 EPS15L1 ITSN1 0.249 22558309,26344197 Q9UBC2 Q3U2S4 EPS15L1 OTUD5 0.236 26496610 Q9UBC2 P35278 EPS15L1 RAB5C 0.236 26496610 Q9UBC2 O14777 EPS15L1 NDC80 0.236 unassigned1304 Q9UBC2 P62993 EPS15L1 GRB2 0.236 21706016 Q9UBC2 P61962 EPS15L1 DCAF7 0.236 27173435,unassigned1312 Q9UBC2 Q96CW1 EPS15L1 AP2M1 0.332 24189400,26186194 Q9UBC2 Q9NZM3 EPS15L1 ITSN2 0.343 22558309,26344197,20697350 Q9UBC2 P0DI81 EPS15L1 TRAPPC2 0.61 25416956,unassigned1304 Q9UBC2 P53350 EPS15L1 PLK1 0.416 27173435,unassigned1312,26496610 Q9UBC2 P63218 EPS15L1 GNG5 0.454 25416956 Q9UBC2 Q92731 EPS15L1 ESR2 0.126 21182203 Q9UBC2 Q92538 EPS15L1 GBF1 0.081 22863883 Q9UBC2 O43149 EPS15L1 ZZEF1 0.081 22863883 Q9UBC2 Q81Y46 EPS15L1 HUTU 0.126 20711500 Q9UBC2 Q9NR09 EPS15L1 BIRC6 0.081 22863883 Q9UKN8 Q9UBC2 GTF3C4 EPS15L1 0.126 unassigned1312 Q9UBU9 Q9UBC2 NXF1 EPS15L1 0.126 22658674 Q9UBC2 P33991 EPS15L1 MCM4 0.126 unassigned1312 Q9UQ88 Q9UBC2 CDK11A EPS15L1 0.126 unassigned1312 Q9UQE7 Q9UBC2 SMC3 EPS15L1 0.126 unassigned1312 Q9UBC2 A3KN83 EPS15L1 SBNO1 0.126 unassigned1312 Q9UBC2 Q14566 EPS15L1 MCM6 0.126 unassigned1312 Q9UBC2 P49736 EPS15L1 MCM2 0.126 unassigned1312 Q9UBC2 Q14683 EPS15L1 SMC1A 0.126 unassigned1312 Q9UBC2 P49757 EPS15L1 NUMB 0.126 23211419 Q9UBC2 Q14C86 EPS15L1 GAPVD1 0.126 unassigned1312 Q9UBC2 Q00613 EPS15L1 HSF1 0.126 unassigned1312 Q9UBC2 Q12955 EPS15L1 ANK3 0.126 unassigned1312 Q9UBC2 P19320 EPS15L1 VCAM1 0.126 22623428 Q9UBC2 Q06945 EPS15L1 SOX4 0.126 unassigned1312 Q9UBC2 Q3UQN2 EPS15L1 FCHO2 0.21 20448150

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 PSD EPS15L1 MI:0362 inference MI:0461 interaction database NDC80 EPS15L1 MI:0362 inference MI:0461 interaction database HGS EPS15L1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database XPO1 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database SPRY2 EPS15L1 MI:0362 inference MI:1106 pathways database SPRY1 EPS15L1 MI:0362 inference MI:1106 pathways database ORC4 EPS15L1 MI:0362 inference MI:0461 interaction database PARK2 EPS15L1 MI:0362 inference MI:0461 interaction database CDC40 EPS15L1 MI:0362 inference MI:0461 interaction database EED EPS15L1 MI:0362 inference MI:0461 interaction database STAM2 EPS15L1 MI:0362 inference MI:1106 pathways database AP2A2 EPS15L1 MI:0362 inference MI:0461 interaction database AGFG2 EPS15L1 MI:0362 inference MI:0461 interaction database EPN2 EPS15L1 MI:0362 inference MI:0461 interaction database ZWINT EPS15L1 MI:0362 inference MI:0461 interaction database AP2A1 EPS15L1 MI:0362 inference MI:0461 interaction database ABL1 EPS15L1 MI:0362 inference MI:0461 interaction database EGFR EPS15L1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database EGF EPS15L1 MI:0362 inference MI:1106 pathways database NTRK1 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database FYN EPS15L1 MI:0362 inference MI:0461 interaction database CLTA EPS15L1 MI:0362 inference MI:0461 interaction database CLTB EPS15L1 MI:0362 inference MI:0461 interaction database UBB EPS15L1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database UBC EPS15L1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TRAPPC2 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database SRC EPS15L1 MI:0362 inference MI:0461 interaction database SLC2A4 EPS15L1 MI:0362 inference MI:0461 interaction database GJA1 EPS15L1 MI:0362 inference MI:0461 interaction database VCAM1 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database CBL EPS15L1 MI:0362 inference MI:1106 pathways database PTPN3 EPS15L1 MI:0362 inference MI:1106 pathways database EPS15 EPS15L1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database NUMB EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database RAB5C EPS15L1 MI:0362 inference MI:0461 interaction database NOVA1 EPS15L1 MI:0362 inference MI:0461 interaction database AGFG1 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database PLK1 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database CLTCL1 EPS15L1 MI:0362 inference MI:0461 interaction database DCAF7 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database RPS27A EPS15L1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database UBA52 EPS15L1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database GRB2 EPS15L1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database AP2B1 EPS15L1 MI:0362 inference MI:0461 interaction database GNG5 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database DAB2 EPS15L1 MI:0362 inference MI:0461 interaction database CYCS EPS15L1 MI:0362 inference MI:0461 interaction database CDKL1 EPS15L1 MI:0362 inference MI:0461 interaction database CLTC EPS15L1 MI:0362 inference MI:0461 interaction database CAV1 EPS15L1 MI:0362 inference MI:0461 interaction database DNM1 EPS15L1 MI:0362 inference MI:0461 interaction database FCHO2 EPS15L1 MI:0362 inference MI:0461 interaction database RASGEF1B EPS15L1 MI:0362 inference MI:0461 interaction database AP1B1 EPS15L1 MI:0362 inference MI:0461 interaction database ITSN1 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database ODF2 EPS15L1 MI:0362 inference MI:0461 interaction database RASGEF1C EPS15L1 MI:0362 inference MI:0461 interaction database RASGEF1A EPS15L1 MI:0362 inference MI:0461 interaction database REPS2 EPS15L1 MI:0362 inference MI:0461 interaction database STON2 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database ESR2 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database STAM EPS15L1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database PRKCDBP EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database SH3KBP1 EPS15L1 MI:0362 inference MI:1106 pathways database AP2M1 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database OTUD5 EPS15L1 MI:0362 inference MI:0461 interaction database SH3GL2 EPS15L1 MI:0362 inference MI:1106 pathways database SGIP1 EPS15L1 MI:0362 inference MI:0461 interaction database EPN3 EPS15L1 MI:0362 inference MI:0461 interaction database SPC25 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database MOV10 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database MED4 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database ITSN2 EPS15L1 MI:0045 experimental interaction detection MI:0461 interaction database EPS15L1 NXF1 MI:0045 experimental interaction detection MI:0461 interaction database EPS15L1 UBQLN1 MI:0045 experimental interaction detection MI:0461 interaction database EPS15L1 ARHGAP26 MI:0362 inference MI:0461 interaction database EPS15L1 NOVA2 MI:0362 inference MI:0461 interaction database EPS15L1 KIAA1107 MI:0045 experimental interaction detection MI:0461 interaction database EPS15L1 EPN1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database EPS15L1 NUMBL MI:0362 inference MI:0461 interaction database