PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ANAPC15 ANAPC13 26496610 biogrid,intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G TAF4 ANAPC13 26344197 biogrid exp P P P P P P P P P P P P P P P P P P P P ANAPC13 NXF1 22658674 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G ANAPC13 MOV10 22658674 biogrid exp G G G G G G G G G G G G G G G G G G G G G G ANAPC13 ANAPC5 22939629,20360068, 25402006 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G ANAPC13 ANAPC7 22939629,20360068, 25402006 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G CDC27 ANAPC13 21043528,22939629,20360068, 25402006 biogrid,intact exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G CDC20 ANAPC13 20360068, 25402006 intact exp, pred P G GP G GP P P GP G G P GP GP GP ANAPC16 ANAPC13 20360068, 25402006 intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G CDC26 ANAPC13 22939629,20360068, 25402006 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G ANAPC13 CDC23 25416956,22939629,26496610,20360068, 25402006 biogrid,intact exp, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G ANAPC13 ANAPC4 25490258,26083744,22939629,25043029,23078409,20360068, 25402006 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G CDC16 ANAPC13 26344197,22939629,20360068, 25402006 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G ANAPC13 ANAPC1 20360068, 25402006 intact exp, pred P P P P P P P P P P P P P P P P P P P ANAPC13 MAD2L2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G ANAPC13 FBXO5 25402006 pred P P G GP P P GP P P P P GP P G P P P P P GP G P P ANAPC13 ANAPC10 25402006, 21836163 pred GP G G G GP GP G GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP G GP GP G USP33 ANAPC13 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G UBE2S ANAPC13 25402006 pred G G G G G G G G GP G G G GP G G G G G G G G G G G GP G ANAPC13 ANAPC11 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G BUB1B ANAPC13 25402006 pred P P G GP P GP GP P P P GP GP P G P GP P P P GP GP GP G ANAPC13 FZR1 25402006 pred G GP G G G GP G GP GP G GP GP GP G G GP GP G P G G GP G GP GP G GP GP G ANAPC13 ANAPC2 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP G GP GP G CCNA1 ANAPC13 25402006 pred G G G G G G G G G G G G G G G PTTG1 ANAPC13 25402006 pred GP G G G GP G G G GP G G G G GP G GP G G G G GP G G G GP G G GP G UBE2C ANAPC13 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G MAD2L1 ANAPC13 25402006 pred P G G P P GP P P P GP G GP P G P P GP P GP G GP GP SPATC1 ANAPC13 25402006 pred P P P P P P P P P P P P GP P P P GP

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CDC27 ANAPC13 MI:0401(biochemical)|MI:0401(biochemical)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification) 20360068,21043528,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0914(association)|MI:0914(association)|MI:0914(association) (biogrid)|(biogrid)|(intact)|(intact) BIOGRID_232960|BIOGRID_207333|UniProt_170235|UniProt_106544 prey|bait|prey|prey bait|prey|bait|bait CCNB1 ANAPC13 MI:0004(affinity chromatography technology) 20080579 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_146768 prey bait PTTG1 ANAPC13 MI:0004(affinity chromatography technology) 20080579 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_146755 prey bait SIRT1 ANAPC13 MI:0004(affinity chromatography technology) 22318606 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0799(additive genetic interaction defined by inequality) (biogrid) BIOGRID_193184 bait prey CDC16 ANAPC13 MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0401(biochemical)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification) 20360068,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0403(colocalization)|MI:0914(association)|MI:0914(association) (intact)|(intact)|(biogrid)|(intact)|(intact) UniProt_170235|UniProt_170231|BIOGRID_232963|UniProt_106540|UniProt_106544 prey|bait|prey|bait|prey bait|prey|bait|prey|bait UBE2C ANAPC13 MI:0004(affinity chromatography technology) 20080579 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_222931 prey bait ANAPC13 ANAPC4 MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0401(biochemical) 20360068,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0403(colocalization) (intact)|(intact)|(biogrid) UniProt_170235|UniProt_106544|BIOGRID_232950 bait|bait|bait prey|prey|prey ANAPC13 ANAPC7 MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0401(biochemical) 20360068,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0403(colocalization) (intact)|(intact)|(biogrid) UniProt_170235|UniProt_106544|BIOGRID_232974 bait|bait|bait prey|prey|prey ANAPC13 ANAPC5 MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0401(biochemical) 20360068,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0403(colocalization) (intact)|(intact)|(biogrid) UniProt_170235|UniProt_106544|BIOGRID_232971 bait|bait|bait prey|prey|prey ANAPC13 CDC23 MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0401(biochemical) 20360068,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0403(colocalization) (intact)|(intact)|(intact)|(intact)|(biogrid) UniProt_170235|UniProt_106544|UniProt_106541|UniProt_170232|BIOGRID_232972 bait|bait|prey|prey|bait prey|prey|bait|bait|prey CDC26 ANAPC13 MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0401(biochemical)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification) 20360068,22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0403(colocalization)|MI:0914(association)|MI:0914(association) (intact)|(intact)|(biogrid)|(intact)|(intact) UniProt_170235|UniProt_170233|BIOGRID_233863|UniProt_106544|UniProt_106542 prey|bait|prey|prey|bait bait|prey|bait|bait|prey UBE2D1 ANAPC13 MI:0004(affinity chromatography technology) 20080579 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_222944 prey bait NRF1 ANAPC13 MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_296734 bait prey

PPI - HINT Gene A Gene B PMID Method Quality TAF4 ANAPC13 26344197 0401 HT CDC27 ANAPC13 20360068,21043528,22939629 0676,0401,0401 LC,HT ANAPC15 ANAPC13 26496610,26496610 0007,0004 HT CDC16 ANAPC13 26344197,20360068,22939629 0401,0676,0401 HT,LC CDC26 ANAPC13 20360068,22939629 0676,0401 LC,HT ANAPC13 CDC23 26496610,26496610,20360068,22939629 0004,0007,0676,0401 HT,LC ANAPC13 ANAPC7 20360068,22939629 0676,0401 LC,HT ANAPC13 ANAPC5 20360068,22939629 0676,0401 LC,HT ANAPC13 ANAPC4 23078409,25043029,20360068,25490258,26083744,22939629 0401,0401,0676,0004,0401,0401 LC,HT TAF4 ANAPC13 26344197 0401 HT CDC27 ANAPC13 22939629 0401 HT ANAPC15 ANAPC13 26496610,26496610 0007,0004 HT CDC16 ANAPC13 26344197,22939629 0401,0401 HT CDC26 ANAPC13 22939629 0401 HT ANAPC13 CDC23 26496610,26496610,22939629 0004,0007,0401 HT ANAPC13 ANAPC7 22939629 0401 HT ANAPC13 ANAPC5 22939629 0401 HT ANAPC13 ANAPC4 22939629 0401 HT CDC27 ANAPC13 20360068,21043528 0676,0401 LC CDC16 ANAPC13 20360068 0676 LC CDC26 ANAPC13 20360068 0676 LC ANAPC13 CDC23 20360068 0676 LC ANAPC13 ANAPC7 20360068 0676 LC ANAPC13 ANAPC5 20360068 0676 LC ANAPC13 ANAPC4 23078409,25043029,20360068,25490258,26083744 0401,0401,0676,0004,0401 LC TAF4 ANAPC13 26344197 0401 LC PTTG1 ANAPC13 20080579 0415 LC CCNB1 ANAPC13 20080579 0415 LC CDC27 ANAPC13 21043528,22939629 0401,0401 LC CDC16 ANAPC13 26344197,22939629 0401,0401 LC CDC26 ANAPC13 22939629 0401 LC ANAPC13 CDC23 25416956,25416956,25416956,25416956,22939629 0397,1112,0018,1356,0401 HT,LC ANAPC13 ANAPC7 22939629 0401 LC ANAPC13 ANAPC5 22939629 0401 LC ANAPC13 ANAPC4 23078409,25043029,26083744,22939629 0401,0401,0401,0401 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9BS18 P60006 ANAPC13 ANAPC15 0.126 26496610 Q9HCE1 Q9BS18 MOV10 ANAPC13 0.126 22658674 Q9BS18 Q8R034 ANAPC13 ANAPC13 0.126 20360068 Q9BS18 Q86T82 ANAPC13 USP37 0.126 26299517 Q9Z1S0 Q9BS18 BUB1B ANAPC13 0.236 20360068 Q9UJX3 Q9BS18 ANAPC7 ANAPC13 0.236 20360068 Q9BS18 Q13042 ANAPC13 CDC16 0.386 20360068,26344197 Q9UJX4 Q9BS18 ANAPC5 ANAPC13 0.236 20360068 Q9CPV2 Q9BS18 ANAPC16 ANAPC13 0.236 26496610 Q9BS18 Q8BZQ7 ANAPC13 ANAPC2 0.236 26496610 Q9BS18 Q99JP4 ANAPC13 CDC26 0.332 26496610,20360068 Q9UJX2 Q9BS18 CDC23 ANAPC13 0.636 25416956,unassigned1304,20360068,26496610 Q9JJ66 Q9BS18 CDC20 ANAPC13 0.416 26496610,20360068 Q9BS18 Q8BGZ4 ANAPC13 CDC23 0.416 26496610,20360068 Q9BS18 Q8R349 ANAPC13 CDC16 0.416 26496610,20360068 Q9BS18 P30260 ANAPC13 CDC27 0.396 20360068,21043528 Q9BS18 Q96DE5 ANAPC13 ANAPC16 0.236 20360068 Q9BS18 Q8NHZ8 ANAPC13 CDC26 0.332 20360068 Q9H1A4 Q9BS18 ANAPC1 ANAPC13 0.236 20360068 Q9UJX5 Q9BS18 ANAPC4 ANAPC13 0.702 25490258,20360068,26083744,23078409,25043029 Q9UBU9 Q9BS18 NXF1 ANAPC13 0.126 22658674 Q9BS18 Q12834 ANAPC13 CDC20 0.332 20360068

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 PJA2 ANAPC13 MI:0362 inference MI:0461 interaction database MARCH6 ANAPC13 MI:0362 inference MI:0461 interaction database BUB1B ANAPC13 MI:0362 inference MI:0461 interaction database VAMP4 ANAPC13 MI:0362 inference MI:0461 interaction database ITGA2 ANAPC13 MI:0362 inference MI:0461 interaction database MSN ANAPC13 MI:0362 inference MI:0461 interaction database MGAT1 ANAPC13 MI:0362 inference MI:0461 interaction database CDC27 ANAPC13 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database USP11 ANAPC13 MI:0362 inference MI:0461 interaction database KIF11 ANAPC13 MI:0362 inference MI:0461 interaction database ANAPC15 ANAPC13 MI:0045 experimental interaction detection MI:0461 interaction database TPM4 ANAPC13 MI:0362 inference MI:0461 interaction database ATP7A ANAPC13 MI:0362 inference MI:0461 interaction database DMWD ANAPC13 MI:0362 inference MI:0461 interaction database CDC20 ANAPC13 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database CDC16 ANAPC13 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database STX3 ANAPC13 MI:0362 inference MI:0461 interaction database USP37 ANAPC13 MI:0045 experimental interaction detection MI:0461 interaction database ZC3H3 ANAPC13 MI:0362 inference MI:0461 interaction database CDC26 ANAPC13 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC16 ANAPC13 MI:0045 experimental interaction detection MI:0461 interaction database SIPA1 ANAPC13 MI:0362 inference MI:0461 interaction database FYTTD1 ANAPC13 MI:0362 inference MI:0461 interaction database ANAPC13 ARHGAP39 MI:0362 inference MI:0461 interaction database ANAPC13 ANAPC1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC13 MOV10 MI:0045 experimental interaction detection MI:0461 interaction database ANAPC13 ANAPC11 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database ANAPC13 NXF1 MI:0045 experimental interaction detection MI:0461 interaction database ANAPC13 CDC23 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC13 ANAPC7 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC13 ANAPC5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC13 ANAPC4 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC13 ANAPC2 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database ANAPC13 FBXO5 MI:0362 inference MI:0461 interaction database ANAPC13 FZR1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database ANAPC13 ANAPC10 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database