PTM - CPLM Gene Name UniProt ID Type Position Code ARPC1B; ARC41 O15143 Acetylation 44 K ARPC1B; ARC41 O15143 Acetylation 82 K ARPC1B; ARC41 O15143 Acetylation 174 K ARPC1B; ARC41 O15143 Ubiquitination 82 K ARPC1B; ARC41 O15143 Ubiquitination 110 K ARPC1B; ARC41 O15143 Ubiquitination 18 K ARPC1B; ARC41 O15143 Ubiquitination 174 K ARPC1B; ARC41 O15143 Ubiquitination 341 K ARPC1B; ARC41 O15143 Ubiquitination 326 K ARPC1B; ARC41 O15143 Ubiquitination 308 K ARPC1B; ARC41 O15143 Ubiquitination 289 K ARPC1B; ARC41 O15143 Ubiquitination 367 K ARPC1B; ARC41 O15143 Ubiquitination 37 K ARPC1B; ARC41 O15143 Ubiquitination 49 K ARPC1B; ARC41 O15143 Ubiquitination 87 K ARPC1B; ARC41 O15143 Ubiquitination 339 K ARPC1B; ARC41 O15143 Ubiquitination 360 K ARPC1B; ARC41 O15143 Ubiquitination 370 K ARPC1B; ARC41 O15143 Ubiquitination 372 K

PTM - dbPAF Gene Name UniProt ID Position Type Species ARPC1B; ARC41 O15143 170 S Homo sapiens(Human) ARPC1B; ARC41 O15143 172 Y Homo sapiens(Human) ARPC1B; ARC41 O15143 21 T Homo sapiens(Human) ARPC1B; ARC41 O15143 297 T Homo sapiens(Human) ARPC1B; ARC41 O15143 310 S Homo sapiens(Human) ARPC1B; ARC41 O15143 311 S Homo sapiens(Human) ARPC1B; ARC41 O15143 315 T Homo sapiens(Human) ARPC1B; ARC41 O15143 328 S Homo sapiens(Human) ARPC1B; ARC41 O15143 330 S Homo sapiens(Human) ARPC1B; ARC41 O15143 336 S Homo sapiens(Human) ARPC1B; ARC41 O15143 35 Y Homo sapiens(Human) ARPC1B; ARC41 O15143 355 S Homo sapiens(Human) ARPC1B; ARC41 O15143 361 S Homo sapiens(Human) ARPC1B; ARC41 O15143 364 S Homo sapiens(Human) ARPC1B; ARC41 O15143 89 T Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O15143 K18-ac Acetylation ISCHAWNkDRtQIAI O15143 K37-ac Acetylation HEVHIyEkSGAkWTk O15143 K41-ac Acetylation IyEkSGAkWTkVHEL O15143 K44-ac Acetylation kSGAkWTkVHELKEH O15143 K82-ac Acetylation NAyVWTLkGRTWKPT O15143 K174-ac Acetylation RIFsAyIkEVEERPA O15143 K326-m1 Methylation AGLDsLHkNsVSQIS O15143 T21-p Phosphorylation HAWNkDRtQIAICPN O15143 Y35-p Phosphorylation NNHEVHIyEkSGAkW O15143 Y77-p Phosphorylation CGTDRNAyVWTLkGR O15143 S170-p Phosphorylation DFKCRIFsAyIkEVE O15143 Y172-p Phosphorylation KCRIFsAyIkEVEER O15143 T183-p Phosphorylation VEERPAPtPWGsKMP O15143 S187-p Phosphorylation PAPtPWGsKMPFGEL O15143 T297-p Phosphorylation QSSQRGLtARERFQN O15143 S310-p Phosphorylation QNLDKkAssEGGtAA O15143 S311-p Phosphorylation NLDKkAssEGGtAAG O15143 T315-p Phosphorylation kAssEGGtAAGAGLD O15143 S323-p Phosphorylation AAGAGLDsLHkNsVS O15143 S328-p Phosphorylation LDsLHkNsVSQISVL O15143 S336-p Phosphorylation VSQISVLsGGKAKCS O15143 S355-p Phosphorylation TGMDGGMsIWDVKsL O15143 S361-p Phosphorylation MsIWDVKsLESALkD O15143 K18-ub Ubiquitination ISCHAWNkDRtQIAI O15143 K44-ub Ubiquitination kSGAkWTkVHELKEH O15143 K82-ub Ubiquitination NAyVWTLkGRTWKPT O15143 K110-ub Ubiquitination RWAPNENkFAVGSGS O15143 K138-ub Ubiquitination WWVCKHIkKPIRSTV O15143 K289-ub Ubiquitination GGRLDVPkQSSQRGL O15143 K308-ub Ubiquitination RFQNLDKkAssEGGt O15143 K367-ub Ubiquitination KsLESALkDLKIK__

PTM - dbPTM UniProt ID Position Code Type Resources References O15143 2 A Acetylation Swiss-Prot 1010711 19413330 O15143 44 K Acetylation Swiss-Prot 1010711 19608861 O15143 82 K Acetylation Swiss-Prot 1010711 19608861 O15143 310 S Phosphorylation Swiss-Prot 1010711 17287340 O15143 310 S Phosphorylation PhosphoELM.10011 17287340 O15143 315 T Phosphorylation PhosphoELM.10011 17081983 O15143 110 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 O15143 82 K Ubiquitylation Phosphositeplus.1010730 21890473 O15143 44 K Acetylation Phosphositeplus.1010730 19608861 O15143 82 K Acetylation Phosphositeplus.1010730 19608861 O15143 170 S Phosphorylation Phosphositeplus.1010730 20068231;20736484;21406692 O15143 310 S Phosphorylation Phosphositeplus.1010730 17287340 O15143 311 S Phosphorylation Phosphositeplus.1010730 18707149 O15143 355 S Phosphorylation Phosphositeplus.1010730 20068230 O15143 21 T Phosphorylation Phosphositeplus.1010730 14749719;20603326 O15143 297 T Phosphorylation Phosphositeplus.1010730 20068230 O15143 172 Y Phosphorylation Phosphositeplus.1010730 20068231;21406692 O15143 44 K Acetylation HPRD 9.0 19608861 O15143 82 K Acetylation HPRD 9.0 19608861 O15143 170 S Phosphorylation HPRD 9.0 19651622,20068231 O15143 310 S Phosphorylation HPRD 9.0 17081983,17287340,20068231 O15143 311 S Phosphorylation HPRD 9.0 18707149 O15143 328 S Phosphorylation HPRD 9.0 20068231 O15143 330 S Phosphorylation HPRD 9.0 20068231 O15143 336 S Phosphorylation HPRD 9.0 20068231 O15143 89 T Phosphorylation HPRD 9.0 20068231 O15143 315 T Phosphorylation HPRD 9.0 17081983 O15143 172 Y Phosphorylation HPRD 9.0 19651622,20068231 O15143 21 T Phosphorylation (PAK1) HPRD 9.0 14749719 O15143 310 S Phosphorylation SysPTM 1.1 17081983 O15143 311 S Phosphorylation SysPTM 1.1 18707149 O15143 315 T Phosphorylation SysPTM 1.1 17081983

PTM - HPRD Symbol Position Code Type References ARPC1B 170 S Phosphorylation 19651622,20068231 ARPC1B 172 Y Phosphorylation 19651622,20068231 ARPC1B 21 T Phosphorylation 14749719 ARPC1B 310 S Phosphorylation 17081983,17287340,20068231 ARPC1B 311 S Phosphorylation 18707149 ARPC1B 315 T Phosphorylation 17081983 ARPC1B 328 S Phosphorylation 20068231 ARPC1B 330 S Phosphorylation 20068231 ARPC1B 336 S Phosphorylation 20068231 ARPC1B 44 K Acetylation 19608861 ARPC1B 82 K Acetylation 19608861 ARPC1B 89 T Phosphorylation 20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type O15143 315 T 17081983 HTP Phosphorylation O15143 310 S 17287340 HTP Phosphorylation

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type ARPC1B IPI00005160 K 43 SGAKWTaKVHELKE acetylation ARPC1B IPI00005160 K 81 AYVWTLaKGRTWKP acetylation ARPC1B IPI00005160 S 169 FKCRIFpSAYIKEV phosphorylation ARPC1B IPI00005160 S 309 NLDKKApSSEGGTA phosphorylation ARPC1B IPI00005160 T 314 ASSEGGpTAAGAGL phosphorylation ARPC1B IPI00005160 Y 171 CRIFSApYIKEVEE phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 10095 115402 - K Ubiquitination 21139048 10095 115402 - K Ubiquitination 21890473 10095 115402 - K Ubiquitination 21906983 10095 115402 - K Ubiquitination 23000965 10095 115402 - K Ubiquitination 24654937 10095 115402 - K Neddylation 24654937 10095 115402 - K Sumoylation 24654937 10095 115402 - K Ubiquitination 24816145 10095 115402 - K Sumoylation 25027693

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID ARPC1B Homo sapiens (Human) 82 "82,AYVWTLKGRTWKP" 82:21890473 ARPC1B Homo sapiens (Human) 40; 243 "40,QKDGVWKPTLVIL; 243,SKLDIPKQSIQRN" 40:21890473; 243:21890473 ARPC1B Homo sapiens (Human) 82; 110 "82,AYVWTLKGRTWKP; 110,WAPNENKFAVGSG" "82:21890473; 110:21906983,21890473" ARPC1B Homo sapiens (Human) 82 "82,AYVWTLKGRTWKP" 82:21890473 ARPC1B Homo sapiens (Human) 110 "110,WAPNENKFAVGSG" 110:21906983 ARPC1B Homo sapiens (Human) 82; 110 "82,AYVWTLKGRTWKP; 110,WAPNENKFAVGSG" "82:21890473; 110:21906983,21890473" ARPC1B Homo sapiens (Human) 82; 110 "82,AYVWTLKGRTWKP; 110,WAPNENKFAVGSG" "82:21890473; 110:21890473,21906983" ARPC1B Homo sapiens (Human) 82; 110 "82,AYVWTLKGRTWKP; 110,WAPNENKFAVGSG" 82:21890473; 110:21890473 ARPC1B Homo sapiens (Human) 82; 110 "82,AYVWTLKGRTWKP; 110,WAPNENKFAVGSG" 82:21890473; 110:21890473 ARPC1B Homo sapiens (Human) 82; 110 "82,AYVWTLKGRTWKP; 110,WAPNENKFAVGSG" "82:21890473; 110:21906983,21890473"