PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus MAP3K10 SMAD4 bci exp P P P P P P P P P P P P P P P P P P P MAP3K10 RANBP9 20936779 i2d exp P P P P P P P P P P P P P P P P P P P P P YWHAE MAP3K10 9427749 hprd,biogrid exp P P P P P P P P P P P P P P P P P P P P P HGS MAP3K10 19019082 biogrid exp P P P P P P P P P P P P P P P P P P ALDH3A2 MAP3K10 20936779 i2d exp P P P P P P P P P P P P P P P P P P P P P DNM1L MAP3K10 9742220 hprd,bci exp P P P P P P P P P P P P P P P P P P P P P MAP3K10 PCGF3 20936779 i2d exp P P P P P P P P P P P P P P P P P P P P P MAP3K10 NEUROD1 12881483 biogrid exp P P P P P P TF MAP3K10 20936779 i2d exp P P P P P P P P MAP3K10 MAPK14 11278395 biogrid exp P P P P P P P P P P P P P P P P P P P P MAP3K10 KIFAP3 9427749 hprd,biogrid,bci exp P P P P P P P P P P P P P P P P P P P P P MAPK1 MAP3K10 11278395 innatedb,biogrid exp P P P P P P P P P P P P P P P P P P P P P COPS2 MAP3K10 15062575 biogrid exp P P P P P P P P P P P P P P P P P P P P MAP3K10 ZMYM2 20936779 i2d exp P P P P P P P P P P P P P P P P P P P MAP3K10 RACGAP1 9427749 hprd exp P P P P P P P P P P MAP3K10 DAXX bci exp P P P P P P P P P P P P P P P P P P P P P MAP3K10 CDK12 bci exp P P P P P P P P P P P P P P P P P P P P P CEACAM1 MAP3K10 11850617 hprd,bci exp P P P P P P P P P FAM13A MAP3K10 20936779 i2d exp P P P P P P P P P P P P P P P P P P P P MAP3K10 KIF26A 20936779 i2d exp P P P P P P P MAP3K10 TTN bci exp P P P P P P P P P P P P P TUBB MAP3K10 9629920 hprd,bci exp P P P P P P P P P P P P P P P P P P P P P HPCA MAP3K10 9427749 biogrid exp P P P P P P P P RAC2 MAP3K10 bci exp P P P P P P P P P P P MAP3K10 LARP6 20936779 i2d exp P P P P P P P P P P P P P P P P P P P P P HNRNPK MAP3K10 20936779 i2d exp P P P P P P P P P P P P P P P P P P P P P PHB MAP3K10 9629920 hprd,bci exp P P P P P P P P P P P P P P P P P P P P P SPTBN2 MAP3K10 20936779 i2d exp P P P P P P P P P P P P P P IRAK1 MAP3K10 bci exp P P P P P P P P P P P P P P P P P P P P MAP3K10 SMG1 bci exp P P P P P P P P P P P P P P P P P P NEFL MAP3K10 20936779 i2d exp MAP3K10 DNM1 9742220 biogrid exp P P P P P GARS MAP3K10 21988832 biogrid,intact exp P P P P P P P P P P P P P P P P P P P P P MAP3K10 DAPK2 bci exp MAP3K10 MAP3K10 20936779,11278395, 23023127 innatedb,biogrid,i2d exp, pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 PRKCZ 20936779, 23023127 i2d exp, pred P P P P P P P P P P P P P P P P P P MAP2K4 MAP3K10 9182538, 23023127, 21836163 hprd,biogrid,bci exp, pred P P P P P P P P P P P MAP3K10 CNKSR1 15753034, 21836163 hprd,i2d,bci exp, pred P P P P P P P P P P P P P P P P P P P MAP3K10 MAP4K1 25402006, 23023127 bci exp, pred P P P P P IGF1R MAP3K10 23023127 bci exp, pred P P P P P P P P P P P P P P P P MAP3K10 SH3RF1 14504284, 23023127 hprd exp, pred RAC1 MAP3K10 9427749, 21836163 biogrid,bci exp, pred P P P P P P P P P P P P MAP3K10 CAMKK2 23023127 bci exp, pred P P P P P P P P P P P P P P P P P P P P MAPK8 MAP3K10 23023127, 21836163 bci exp, pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 KIF3A 9427749, 21836163 hprd,biogrid,bci exp, pred P P P P P P P P HTT MAP3K10 10801775, 25402006 hprd,biogrid,bci exp, pred P P P P P P P P P P P P P P P P P P P MAP3K10 MAP3K12 25402006, 23023127 bci exp, pred P P P P P P P P P P P P P P P P P MAPK9 MAP3K10 11278395, 23023127 innatedb,biogrid exp, pred P P P P P P P P P P P P P P P P P P MAP3K10 TNK1 23023127 bci exp, pred P P P P P P P P P P P P P P P P P P CDC42 MAP3K10 9427749, 25402006 hprd,biogrid,bci exp, pred P P P P P P P P P P P P P P P P P P P P P ABL2 MAP3K10 20936779, 23023127 biogrid,i2d,intact exp, pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 MAP3K11 25402006, 23023127 bci exp, pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 MAP3K5 23023127 bci exp, pred P P P P P P P P P P P P P KIF3B MAP3K10 9427749, 21836163 hprd,bci exp, pred P P P P P P P P P P P P P P P P MAP3K10 MAP4K5 23023127 bci exp, pred P P P P P P P P P P CLTC MAP3K10 12105200, 21836163 hprd,biogrid,bci exp, pred P P P P P P P P P P P P P P P P P P P MAP3K10 PKN1 23023127 bci exp, pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 MAPK8IP1 10490659, 23023127 hprd,biogrid exp, pred P P P P P P P P P P P P P P P P P P P P MAP3K10 KIF17 9427749, 21836163 biogrid exp, pred P P P P P P P P P P P P P P P P P P P P AKT1 MAP3K10 25402006, 23023127 bci exp, pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 PPP1R13B 20936779, 23023127 i2d exp, pred P P P P P P P P P P P P P P P P P P P P P DLG4 MAP3K10 11152698, 23023127 hprd,biogrid exp, pred P P MAP3K10 MAPK8IP2 10490659, 25402006, 23023127 hprd,biogrid,bci exp, pred P P P P P P P P P P P P P P P P P P P MAP3K9 MAP3K10 25402006, 23023127 bci exp, pred P P P P P P P P P P P P P P P P P P P MAP3K10 MLK4 20936779, 25402006, 23023127 biogrid,i2d,intact exp, pred P P P P P P P P P P P P P P P P P MAP3K10 TAOK3 23023127 bci exp, pred P P P P P P P P P P P P P P P P P P P P MAP3K10 PAK1 23023127 bci exp, pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 MIA3 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 RCHY1 23023127 pred P P P P P P P P P P P SH2D1A MAP3K10 23023127 pred MAP3K10 PAK7 23023127 pred P P P P P P P P P P P P P P MAP3K10 EIF5A2 23023127 pred P P P P P P P P P P P P P P P P P P P P P STK25 MAP3K10 23023127 pred P P P P P P P P P P P P P MAP3K10 TTBK2 23023127 pred P P P P P P P P P P P P P P P P SORBS2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P VAV1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 MINK1 23023127 pred P P P P P P P P P P P P P P P P MAP3K10 TIAM1 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 FGD4 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 PAK6 23023127 pred P P P P P P P P P P P P P P P RASGRP1 MAP3K10 23023127 pred CACNB4 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 ARHGEF4 23023127 pred P P P P P P P P P P P P P PDLIM1 MAP3K10 21836163 pred P P P P P P P P P P P P P P P P P P P MAP3K10 MIA2 23023127 pred P P P P P P P P P P P P P P MAP3K10 NCF4 23023127 pred P P P P MAP3K10 NCF4 23023127 pred P P P P MAP3K10 SQSTM1 23023127 pred P P P P P P P P P P P P P P P P P P UBE2K MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P P P P P EPHA5 MAP3K10 23023127 pred MATK MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 ARHGEF6 23023127 pred P P P P P P P P P P P P MAP3K10 STAC3 23023127 pred MAP3K10 RUSC1 23023127 pred P P P P P P P P P P P P P P P P P P P PHF20L1 MAP3K10 23023127 pred P P P P P P P P P P P P PIK3R2 MAP3K10 25402006, 23023127 pred MAP3K10 MAPK8IP3 21836163 pred P P P P P P P P P P P P P P P P P P P P P PTPN4 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P RGS14 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 PLK2 23023127 pred P P P P P P P P P P P P P P P P P P P P P BZRAP1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P P2RY4 MAP3K10 25402006 pred P P P P P P P P P P P P P P P HCLS1 MAP3K10 23023127 pred P P P P P P PDGFRA MAP3K10 23023127 pred P P P P P P P MAP3K10 MAP3K1 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 EPHA7 23023127 pred P P P P P P P P P P P P P P P P P P P DNASE1 MAP3K10 25402006 pred P P P P P P MAP3K10 ZAK 25402006, 23023127 pred P P P P P P P P P P P P P P P DVL1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MTSS1 MAP3K10 25402006 pred MAP3K10 MAP3K4 25402006, 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 NOXO1 23023127 pred MAP3K10 CUZD1 21836163 pred EGFR MAP3K10 23023127 pred P P P P P P P P P P P P P P ARHGEF11 MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 RYR2 23023127 pred P P P P P P P P PARK2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P MAP3K10 BAG1 23023127 pred P P P P P P P P P P P P P P P P P P P P P RASGRF2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 DOK4 23023127 pred P P P P P P P P P P P P P P P P P P MAP3K10 TMUB2 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 SH3GLB1 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 DLG3 23023127 pred P P P P P P PAK3 MAP3K10 25402006, 23023127 pred P P P P VAV2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P MCF2L MAP3K10 25402006 pred P P P P P P P P P P P P P P P MAP3K10 BMPER 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 ABI2 23023127 pred SOCS7 MAP3K10 23023127 pred MAP3K10 ITK 23023127 pred MAP3K10 CCRN4L 25402006 pred P P P P P P P P P P MAP3K10 HIPK3 23023127 pred P P P P P P P P P P P P P P P P P P P P RIMBP2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 RGL3 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 RUSC2 23023127 pred P P P P P P P P P P P P P P P P P P P P P DCLK1 MAP3K10 23023127 pred P P P P P P P P P P P MAP3K10 BAIAP2L1 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 PIWIL2 25402006 pred MAP3K10 DVL3 23023127 pred P P P P P P P P P P P P P P P P P P P P P PDPK1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P MAP3K10 UBXN11 23023127 pred P P P P P P P P P P P P P P P P P MAP3K10 ABI3 23023127 pred P P P P P P P P P P P P NCR2 MAP3K10 25402006 pred P MAP3K10 PRKCQ 23023127 pred MAP3K10 SH3GL2 23023127 pred P P CDC42EP1 MAP3K10 25402006 pred P P P P P P P P P P P P P P P P BCAR1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P ACVR1B MAP3K10 23023127 pred P P P P P P P P P P P MAP3K10 STAM 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 MYO15A 23023127 pred P P P P P P P P P P P P MAP3K10 NCKIPSD 25402006 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 UBQLN2 23023127 pred P P P P P P P P P P P P P P P P P P P P P FXR2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P TCERG1 MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P P MAP3K10 RASD2 23023127 pred P P P P P P P P P P P P P P ACRV1 MAP3K10 25402006 pred P MAP3K10 SPRED3 23023127 pred MAP3K10 ARHGEF26 21836163 pred P P P P P P P P P P P P PLA2G6 MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P P P MAP3K10 PACSIN3 23023127 pred P P P P P P P P P P P P P P P P P P MAP3K10 SH3GLB2 23023127 pred P P P P P P P P P P MAP3K10 FMR1 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 PACSIN1 23023127 pred P P P P MAP3K10 AHI1 23023127 pred P P P P P P P P P P P P P P P P P MAP3K10 SNX18 23023127 pred P P P P P P P P P P P P P P P P P MAP3K10 SH2D3C 23023127 pred P P P P P P P P P MAP3K10 ITSN2 23023127 pred P P P P P P P P P P P MAP3K10 CNKSR2 23023127 pred P P P P P P P P P P P P P P P P P P MAP3K10 AKTIP 23023127 pred P P P P P P P P P P P P P P P P P P P P P FLT3 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P AXIN1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P F12 MAP3K10 23023127 pred P P P P P P MAP3K10 EPB41L4B 23023127 pred P P P P P P P P P P P P P P P P P P P P DVL2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 UBL4B 23023127 pred P P P P P P P P P P P P P P P P P P P FGF9 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 UBASH3B 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 SRGAP1 23023127 pred P P P P P P P P P SRGAP2 MAP3K10 23023127 pred CX3CL1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 MAPK6 25402006 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 STK31 23023127 pred P P P P P P P P P P P MAP3K10 OSTF1 23023127 pred P P P P P P P P P P P P P P P P P P P P PRKCG MAP3K10 23023127 pred P P MAP3K10 COL4A3BP 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 ALS2CL 25402006 pred P P P P P P P P P P P P P P P P P P P P P HNF4A MAP3K10 25402006 pred P P P P P P P P P P CSNK1G2 MAP3K10 23023127 pred P P P P MAP3K10 CAMK2B 23023127 pred P P P P P P CSH2 MAP3K10 25402006 pred ULK1 MAP3K10 23023127 pred FRK MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P ADRBK2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P YES1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 A1CF 25402006 pred P P P P P P P P P P KALRN MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P ARHGEF37 MAP3K10 23023127 pred P P P P P P P P P P P P P SORBS3 MAP3K10 23023127 pred P P P P P P P P P P P P P MAP3K10 ARHGEF7 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 SNX9 23023127 pred P P P P P P P P P P P P P P P P P P P P P UBASH3A MAP3K10 23023127 pred P P P P P IKBKAP MAP3K10 25402006 pred P P P P P P P P P P P P P MAP3K10 PTK2B 23023127 pred P P P P P P P P P P P P P P P ACTL6B MAP3K10 25402006 pred P P P P P P P P MAP3K10 BIRC7 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 PSD3 23023127 pred AKT2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 MPP7 23023127 pred P P P P P P P P P P P P P P P P P P P P P CBS MAP3K10 25402006 pred P P P OPHN1 MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 SCN10A 25402006 pred MAP3K10 PPP1R13L 23023127 pred P P P P P P P P P P P P P P P P P P ALPI MAP3K10 25402006 pred P P P P P P GDF9 MAP3K10 25402006 pred MAP3K10 GRK1 23023127 pred MAP3K10 AGAP3 23023127 pred P P P P P P P P P P P P P P P P P P MAP3K10 ASH1L 23023127 pred P P P P P P P P P P P P SH3D21 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 SLA2 23023127 pred NEBL MAP3K10 23023127 pred P P P P P P P P P P P P MAP3K10 FARP1 23023127 pred P P P P P TRIO MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P SH3PXD2B MAP3K10 23023127 pred P P P P P P P P P P P P P MAP3K10 DNMT3B 23023127 pred P P P P P P P P P P P P P P P P P P P P P FYN MAP3K10 23023127 pred P P P P P P P P P MAP3K10 OBSCN 23023127 pred P P P P P P P P P P P P P P P P P P P P P GPR12 MAP3K10 25402006 pred P P P P SASH3 MAP3K10 23023127 pred P P P P P P P P P P P P MAP3K10 DLG2 23023127 pred P P P P P P P P P P PFN2 MAP3K10 25402006 pred P P P P P P P P P P P P P P P P MAP3K10 ASAP1 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 MIB2 23023127 pred P P P P P P P P P P P P P P P P P P P P SYK MAP3K10 23023127 pred P P P P P P P P P P P P P MAP3K10 TDRKH 23023127 pred P P P P P P P P P P P P P P P P P P P P P TUB MAP3K10 25402006 pred P P P P P HAP1 MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P P P P SOCS5 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 CDKL2 23023127 pred P P P P P P P P P P P P P P P P MAP3K10 MTA3 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP2K1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 TRIB1 23023127 pred MAP3K10 SUMO4 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 SKAP1 23023127 pred P P P P SUMO2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P PRKAR2B MAP3K10 23023127 pred P P P P P P P P P P P P P ZAP70 MAP3K10 23023127 pred P P P PRKCB MAP3K10 23023127 pred P P P P P P P P P P P P P P P MAP3K10 HIPK2 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 RAPGEFL1 23023127 pred P P P P P P P P P P P P MAP3K10 ACVR1C 23023127 pred P P P P P P P P P P MAP3K10 PLEKHA1 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 MPP2 23023127 pred P P P P P P MAP3K10 CLIP4 23023127 pred P P P P P P P P P P P P MAP3K10 CTTN 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 SRMS 23023127 pred P P P P P P P P P P P P P P P P P P P P P UBC MAP3K10 23023127 pred NCK1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 STAC 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 MAPK11 25402006 pred P P P P P P P P P P P P P P P P P P P P P AP2A1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P SBF1 MAP3K10 23023127 pred BIN1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K13 MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P P P CDC42EP2 MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P MAP3K10 DBNL 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 ARHGEF16 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 STMN3 23023127 pred P P P P P P MAP3K10 MAP3K3 25402006, 23023127 pred P P P P P P P P P P P P MAP3K10 LMTK2 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 FAF1 23023127 pred P P P P P P P P P P P P P P P P P P P P EFS MAP3K10 23023127 pred P P P P P P P P P P P UBE2N MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 UBLCP1 23023127 pred P P P P P P P P P P P P P P P P P P P FGF12 MAP3K10 23023127 pred MAP3K10 ITPK1 25402006 pred P P P P P P P P P P P MAP3K10 MAP3K2 25402006, 23023127 pred P P P P P P P P P P P P P P P MAP3K10 EPS8L3 23023127 pred P P P P P P P P P P P P MAP3K6 MAP3K10 25402006, 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 DGKB 23023127 pred UBL4A MAP3K10 23023127 pred P P P P P P P P P MAP3K10 NPTN 23023127 pred P P P P P P P P P P AMPH MAP3K10 23023127 pred P P P MAP3K10 PIN1 23023127 pred P P P P P P P P P P MAP3K10 ABI1 23023127 pred P P P P P P P P P P P P P P P P P P P P P SUMO1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 PRKCD 23023127 pred P P P P P P P P P P P P P P P P P P P P P RHOG MAP3K10 21836163 pred P P P P P P P P P MAP3K10 LRP11 23023127 pred ARHGAP4 MAP3K10 23023127 pred P P P P PIK3CA MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 CD2AP 23023127 pred P P P P P P P P P P P P P P P P P P NF2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P CACNB3 MAP3K10 23023127 pred MAP3K10 SAMSN1 23023127 pred P P P P P P P P P P P P P P P P P P P SHC1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P ABL1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 NGEF 23023127 pred P P P P P P P P P P P P P P P P P P P P FCHSD2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P HCK MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P PLCG2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P MAP3K10 UBQLN1 23023127 pred P P P P P P P P P P P P P P P P P P P P P CRKL MAP3K10 23023127 pred P P P P P P P P P P P P P DGKE MAP3K10 23023127 pred P P P P P P P P P P P P P P P MAP3K10 UBL7 23023127 pred P P P P P P P P P P P P P P P P P P P P SEMA7A MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P P P MAP3K10 MAP1LC3A 23023127 pred P P P P P P P P MAP3K10 DPF1 23023127 pred P P P P P P P GRB2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P ACVR2A MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 DOK6 23023127 pred P P P P P P P P P P P P P SPTBN1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 MAP4K2 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 STUB1 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 SH3YL1 23023127 pred P P P P P P P P P P P P P P P BAG6 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P DGKQ MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P RIMBP3C MAP3K10 23023127 pred P P P P MAP3K7 MAP3K10 25402006, 23023127 pred P P P P P P P P P P P KIT MAP3K10 23023127 pred P P P P P DFFA MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P UCHL1 MAP3K10 23023127 pred P P P P P MAP3K10 NOXA1 23023127 pred P P P P P P P P P P P P P P P SASH1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P MAP3K10 MYO1E 23023127 pred P P P P P P P P P P P P P P P P P MAP3K10 HERPUD1 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 DGKH 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 AKAP1 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 IKBKE 25402006 pred ALPP MAP3K10 25402006 pred P MAP3K10 VRK1 23023127 pred P P P P P P P P P P P P P P P MAP3K10 SH3RF2 23023127 pred P P P P P P P P P P P P P P P GRAP2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P MAP3K10 HOMER1 23023127 pred P P P MAP3K10 MAPK15 25402006 pred P P P P P P P P P P P P P P P P P P P MAP3K10 SGSM3 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 RGL1 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 EPS8L2 23023127 pred P P P P P P P P P P P P P P P P P P TEK MAP3K10 23023127 pred P P P P P P P P P P P P P P PSD MAP3K10 23023127 pred P P P P P RAD23B MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P ZEB2 MAP3K10 23023127 pred P P P P P P P P P MAP3K10 BTK 23023127 pred P P P P MAP3K8 MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 CIDEC 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 DCTN1 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 ITSN1 23023127 pred P P P P P P P P P P P P P P P P MAP3K10 RAPGEF4 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 NSFL1C 23023127 pred P P P P P P P P P P P P P P P P P P P P MAPK10 MAP3K10 25402006, 23023127 pred P P P P MAP3K10 ARHGAP26 23023127 pred P P P P P P P P P P P P P P P P P PTPN3 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 NELL1 23023127 pred P P P P P P P P P P P P P P P P P P APBA1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 DNMBP 23023127 pred P P P P P P P P P P P P MAP3K10 ITCH 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 PRKAA1 23023127 pred P P P P P P P P P P P P P P P P P P P P P PKIA MAP3K10 23023127 pred P P P P P P P P P P P P P P P P SMNDC1 MAP3K10 23023127 pred MAP3K10 NKX3-1 25402006 pred P P P P P P P P P P P P P P P P P P P MAP3K10 GRIN1 25402006 pred P P P P P P P P P P P P P P P P P P MPP1 MAP3K10 23023127 pred P P P P P P P P P P P P P FER MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 GABARAPL1 23023127 pred P P P P P P P P P P P P P P P P P ARAF MAP3K10 25402006, 23023127 pred PAK4 MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 PTK2 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 RIMBP3 23023127 pred ARHGEF9 MAP3K10 23023127 pred P P P P P P P P P P P P P P NCK2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P RAD23A MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P CIDEA MAP3K10 23023127 pred MAP3K10 SH3RF3 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 WDR17 23023127 pred P P P P P P SRGAP3 MAP3K10 23023127 pred P P P P P P P PRMT2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P MAP3K10 TMUB1 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 MAP3K15 25402006 pred P P P P P P P P P P P P P P P P P P P P DRD5 MAP3K10 25402006 pred P P P P P P CRYBB3 MAP3K10 25402006 pred P P P P P P P P P P P P P MAP3K10 FCHSD1 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 NEUROD2 25402006 pred P MAP3K10 STAC2 23023127 pred P P P P P P P P P P P P P P P P P P LYN MAP3K10 23023127 pred P P P P P P P P P P P P P P MAP3K10 SH3PXD2A 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 PRPF19 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 RPS6KC1 23023127 pred P P P P P P P P P P P P P P P P MAP3K10 C10orf35 23023127 pred P P P P P P P P P SKI MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P RASA1 MAP3K10 23023127 pred P P P P P P APBB1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P MAP3K10 VAV3 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 UBXN2B 23023127 pred P P P P P P P P P P MAP3K10 TRIP10 23023127 pred SUMO3 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 GFRA4 25402006 pred MAP3K10 BAIAP2 23023127 pred P P P P P P P P P P P P P P P P P P P P P USP14 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 EPB41L5 23023127 pred P P P P P P P P P P P P SLIT2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P CDK5 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 SORBS1 23023127 pred P P P P P P P P P P P P P P P P P P P MAP3K10 JAG2 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 CUL3 23023127 pred P P P P P P P P P P P P P P P P P P P P P BRAF MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 SH2D5 23023127 pred P P P P P P P P P P P P P P P P P P P P GABARAPL2 MAP3K10 23023127 pred P P P P P P P P P P P P P RIMBP3B MAP3K10 23023127 pred FYB MAP3K10 23023127 pred P P P CRK MAP3K10 23023127 pred P P P P P P P P P P P P MAP3K10 GIT1 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 ARHGEF19 23023127 pred PRKAR1B MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAPK4 MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 CLIP3 23023127 pred P P P P P P P P P P P P P P P P P P PRKCI MAP3K10 23023127 pred P P P P P P P P P P P P P MAP3K10 MYO15B 23023127 pred MAP3K10 PTPLAD1 23023127 pred P P P P P P P P P P P P P P P P P ARHGAP32 MAP3K10 25402006 pred P P P P P P P P P P P P P P P MAP3K10 BAIAP2L2 23023127 pred P P P P P P P P P P P P P P P P P P P P TEC MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P IQGAP1 MAP3K10 25402006 pred P P P P P P P P P P P P P P P P P P P P JAK2 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P PIK3R1 MAP3K10 25402006, 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 TNFRSF11A 23023127 pred P P P P P P P P P P P P P P P P MAP3K10 TAOK2 23023127 pred P P P P P P P P P P P P P MAP3K10 VRK3 23023127 pred P P P P P P P P P P P P P P P P P P P P MAP3K10 SH3KBP1 23023127 pred P P P P P P MAP3K10 PLCE1 23023127 pred P P P P P P P P P P P P P P P P P P P P P HRAS MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P MAP3K10 UHRF2 23023127 pred P P P P P P P P P P P P P P P P P P P P P ERBB2 MAP3K10 23023127 pred P P P P P P P RAC3 MAP3K10 21836163 pred P P P P P P P P P P P P P P P P P CBX6 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P MAP2K6 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P SOCS1 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P P P P LCK MAP3K10 23023127 pred P P P MAP3K10 LIMS2 23023127 pred P P P P P P MAP3K10 BRSK1 23023127 pred P P P P P P P SOCS3 MAP3K10 23023127 pred P P P P P P P P P P P P P P P P P P MAP3K10 WWC1 23023127 pred P P P P P P P P P P P P P P P P P MAP3K10 CAMKK1 23023127 pred P P P P P P P P P P P P P P P P P P P P P CRYBB1 MAP3K10 25402006 pred MAP3K10 RNF41 23023127 pred P P P P P P P P P P P P P P P P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q02779 - 10801775 - X 2 P45985 Q02779 enzymatic study 9182538 direct interaction X 2 Q02779 Q02779 enzymatic study 11278395 direct interaction X 2 Q02779 P28482-2 enzymatic study 11278395 direct interaction X 2 Q02779 P41250 two hybrid 21988832 direct interaction X 2 Q02779 A0A024RAE4 two hybrid 9427749 direct interaction X 2 Q02779 A0A024RAE4 pull down 9427749 direct interaction X 2 Q02779 A0A0A0MRS8 two hybrid 9427749 direct interaction X 2 Q02779 Q92845-3 two hybrid 9427749 direct interaction X 2 Q02779 P62258 affinity chromatography technology 9427749 physical association X 2 Q02779 Q13387-4 affinity chromatography technology 10490659 physical association X 2 Q02779 Q13387-4 pull down 10490659 direct interaction X 2 Q02779 Q00610 affinity chromatography technology 12105200 physical association X 2 Q02779 B7Z647 affinity chromatography technology 11152698 physical association X 2 Q02779 P42684-2 two hybrid 20936779 direct interaction X 2 Q9UQF2 Q02779 affinity chromatography technology 10490659 physical association X 2 Q9UQF2 Q02779 pull down 10490659 direct interaction X 2 Q02779 P61201-2 two hybrid 15062575 direct interaction X 2 Q02779 P61201-2 pull down 15062575 direct interaction X 2 Q02779 P61201-2 enzymatic study 15062575 direct interaction X 2 Q02779 P45984-2 enzymatic study 11278395 direct interaction X 2 Q02779 Q16539-4 enzymatic study 11278395 direct interaction X 2 Q02779 two hybrid 12881483 direct interaction X 2 Q02779 affinity chromatography technology 12881483 physical association X 2 Q02779 enzymatic study 12881483 direct interaction X 2 Q02779 A4D2P0 pull down 9427749 direct interaction X 2 Q02779 Q9Y496 two hybrid 9427749 direct interaction X 2 Q02779 P84074 affinity chromatography technology 9427749 physical association X 2 Q02779 Q9Y496 affinity chromatography technology 9427749 physical association X 2 Q02779 P42858 affinity chromatography technology 10801775 physical association X 2 Q02779 P42858 affinity chromatography technology 10801775 physical association X 2 Q02779 Q05193 pull down 9742220 direct interaction X 2 Q02779 O14964 pull down 19019082 direct interaction X 2 Q02779 Q5TCX8 two hybrid 20936779 direct interaction X 2 P78352-3 Q02779 in vitro 11152698 - X 2 P78352-3 Q02779 in vitro 11152698 - X 2 P45985 Q02779 in vitro 9182538 - X 2 P45985 Q02779 in vitro 9182538 - X 2 Q02779 A0A024RAE4 in vitro 9427749 - X 2 Q02779 Q00610 in vitro 12105200 - X 2 Q02779 in vivo 10801775 - X 2 Q02779 in vitro 10801775 - X 2 Q02779 A8K401 in vitro 9629920 - X 2 Q02779 A8K401 in vitro 9629920 - X 2 Q02779 O00429-4 in vivo 9742220 - X 2 Q02779 P62258 two hybrid 9427749 - X 2 Q02779 Q7Z6J0 in vitro 14504284 - X 2 Q02779 A0A024RAE4 in vitro 9427749 - X 2 Q02779 Q00610 in vitro 12105200 - X 2 Q02779 E9PBB9 in vivo 10490659 - X 2 Q02779 Q13387-4 in vivo 10490659 - X 2 Q02779 in vitro 10801775 - X 2 Q02779 in vivo 10801775 - X 2 Q02779 Q92845 in vivo 9427749 - X 2 Q02779 Q92845 two hybrid 9427749 - X 2 Q02779 Q92845 in vivo 9427749 - X 2 Q02779 Q92845 two hybrid 9427749 - X 2 Q02779 O00429-4 in vivo 9742220 - X 2 Q02779 E9PBB9 in vivo 10490659 - X 2 Q02779 P62258 two hybrid 9427749 - X 2 Q02779 Q13387-4 in vivo 10490659 - X 2 Q02779 Q7Z6J0 in vitro 14504284 - X 2 O15066 Q02779 two hybrid 9427749 - X 2 O15066 Q02779 in vitro 9427749 - X 2 O15066 Q02779 two hybrid 9427749 - X 2 O15066 Q02779 in vitro 9427749 - X 2 Q02779 P13688-8 in vivo 11850617 - X 2 Q02779 P13688-8 in vitro 11850617 - X 2 Q02779 P07437 in vitro 9629920 - X 2 Q02779 Q9Y496 in vivo 9427749 - X 2 Q02779 Q9Y496 two hybrid 9427749 - X 2 Q02779 Q9Y496 in vitro 9427749 - X 2 Q02779 A0A024R136 in vitro 9427749 - X 2 Q02779 P13688-8 in vitro 11850617 - X 2 Q02779 P13688-8 in vivo 11850617 - X 2 Q02779 Q53GM7 in vivo 15753034 - X 2 Q02779 P07437 in vitro 9629920 - X 2 Q02779 Q9Y496 two hybrid 9427749 - X 2 Q02779 Q9Y496 in vitro 9427749 - X 2 Q02779 Q9Y496 in vivo 9427749 - X 2 Q02779 A0A024R136 in vitro 9427749 - X 2 Q02779 Q53GM7 in vivo 15753034 - X 2 Q02779 P42684 two hybrid pooling approach 20936779 physical association X 2 Q02779 P41250 two hybrid array 21988832 physical association X 2 Q02779 Q5TCX8 two hybrid pooling approach 20936779 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B HPCA MAP3K10 MI:0018(two hybrid) 9427749 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_97975 prey bait COPS2 MAP3K10 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15062575 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_209938|BIOGRID_209936|BIOGRID_209937 prey|bait|bait bait|prey|prey MAP3K10 SH3RF1 MI:0493(in vivo) 14504284 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_6352 - - GARS MAP3K10 MI:0397(two hybrid array)|MI:0004(affinity chromatography technology) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_117108|BIOGRID_287357 unspecified role|bait unspecified role|prey CDC42 MAP3K10 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro) 9427749 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_97956|BIOGRID_97963|HPRD_17225 bait|prey|- prey|bait|- MAP2K4 MAP3K10 MI:0415(enzymatic study)|MI:0492(in vitro) 9182538 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_109016|HPRD_6344 prey|- bait|- RAC1 MAP3K10 MI:0018(two hybrid) 9427749 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_97962 prey bait ABL2 MAP3K10 MI:0096(pull down)|MI:0018(two hybrid) 20936779 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_110521|BIOGRID_126614 prey|prey bait|bait MAP3K10 KIFAP3 MI:0492(in vitro)|MI:0018(two hybrid) 9427749 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_6345|BIOGRID_97968 -|bait -|prey MAP3K10 MAPK8IP2 MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology) 10490659 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0407(direct interaction) (biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_99203|HPRD_33159|BIOGRID_99209 bait|-|bait prey|-|prey MAP3K10 NEUROD1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 12881483 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_88589|BIOGRID_88593|BIOGRID_88591 prey|bait|prey bait|prey|bait MAPK9 MAP3K10 MI:0415(enzymatic study) 11278395 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_270811 bait prey rbcL MAP3K10 MI:0018(two hybrid) 9427749 taxid:85345() taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_97973 prey bait MAP3K10 DNM1 MI:0096(pull down) 9742220 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_103695 bait prey PHB MAP3K10 MI:0492(in vitro) 9629920 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_1264 - - MAP3K10 MAPK14 MI:0415(enzymatic study) 11278395 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_270814 prey bait CLTC MAP3K10 MI:0004(affinity chromatography technology)|MI:0492(in vitro) 12105200 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_106912|HPRD_19865 prey|- bait|- YWHAE MAP3K10 MI:0492(in vitro)|MI:0018(two hybrid) 9427749 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_6351|BIOGRID_97974 -|prey -|bait MAP3K10 KIF3A MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro) 9427749 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_97976|BIOGRID_97967|HPRD_6349 prey|bait|- bait|prey|- MAP3K10 KIF17 MI:0018(two hybrid) 9427749 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_97966 bait prey HGS MAP3K10 MI:0096(pull down) 19019082 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_116265 bait prey TUBB MAP3K10 MI:0492(in vitro) 9629920 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_4396 - - KIF3B MAP3K10 MI:0492(in vitro) 9427749 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_6347 - - MAP3K10 RACGAP1 MI:0492(in vitro) 9427749 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_6350 - - DNM1L MAP3K10 MI:0493(in vivo) 9742220 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_6348 - - MAP3K10 MLK4 MI:0018(two hybrid)|MI:0096(pull down) 20936779 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_127192|UniProt_110522 bait|bait prey|prey MAP3K10 CNKSR1 MI:0493(in vivo) 15753034 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_17574 - - CEACAM1 MAP3K10 MI:0492(in vitro) 11850617 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_7324 - - DLG4 MAP3K10 MI:0004(affinity chromatography technology)|MI:0492(in vitro) 11152698 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_109017|HPRD_6346 bait|- prey|- HTT MAP3K10 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 10801775 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_98753|BIOGRID_98754|HPRD_35891 bait|prey|- prey|bait|- MAPK1 MAP3K10 MI:0415(enzymatic study) 11278395 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_270813 bait prey MAP3K10 MAPK8IP1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 10490659 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_99202|BIOGRID_99208|HPRD_33156 bait|bait|- prey|prey|-

PPI - HINT Gene A Gene B PMID Method Quality KIF3B MAP3K10 9427749 0018 LC MAPK1 MAP3K10 11278395,11278395 0415,0423 LC GARS MAP3K10 21988832,21988832 0397,0018 HT ABL2 MAP3K10 20936779,20936779 0398,0018 HT MAPK9 MAP3K10 11278395,11278395 0415,0423 LC MAP2K4 MAP3K10 9182538 0415 LC CDC42 MAP3K10 9427749,9427749 0096,0018 LC YWHAE MAP3K10 9427749,9427749 0018,0004 LC RAC1 MAP3K10 9427749,9427749 0096,0018 LC MAP3K10 MAP3K10 PDB_2RF0,11278395,11278395 0114,0415,0424 LC MAP3K10 NEUROD1 12881483,12881483,12881483 0018,0004,0415 LC MAP3K10 MAPK14 11278395 0415 LC MAP3K10 Q59EL2 15062575,15062575,15062575 0096,0415,0018 LC MAP3K10 MLK4 20936779,20936779 0398,0018 HT MAP3K10 KIFAP3 9427749,9427749 0018,0004 LC MAP3K10 CNKSR1 15753034 0019 LC MAP3K10 SMURF1 20804422 0415 LC MAP3K10 KIF17 9427749 0018 LC MAP3K10 KIF3A 9427749,9427749 0018,0004 LC MAP3K10 HEL2 9427749,9427749 0018,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q02779 O14964 MAP3K10 HGS 0.309 19019082 Q9HCE7 Q02779 SMURF1 MAP3K10 0.183 20804422 Q02779 P42684 MAP3K10 ABL2 0.286 20936779 Q5TCX8 Q02779 MLK4 MAP3K10 0.286 20936779 Q13387 Q02779 MAPK8IP2 MAP3K10 0.454 10490659 Q9UQF2 Q02779 MAPK8IP1 MAP3K10 0.454 10490659 Q92845 Q02779 KIFAP3 MAP3K10 0.454 9427749 Q02779 P41250 MAP3K10 GARS 0.286 21988832 Q02779 P28482 MAP3K10 MAPK1 0.309 11278395 Q02779 P45984 MAP3K10 MAPK9 0.309 11278395 Q02779 P78352 MAP3K10 DLG4 0.21 11152698 Q02779 P42858 MAP3K10 HTT 0.376 10801775 Q02779 P63000 MAP3K10 RAC1 0.523 9427749 Q02779 P45985 MAP3K10 MAP2K4 0.309 9182538 Q02779 P60953 MAP3K10 CDC42 0.523 9427749 Q02779 P61201 MAP3K10 COPS2 0.671 15062575 Q02779 P62258 MAP3K10 YWHAE 0.21 9427749 Q02779 P84074 MAP3K10 HPCA 0.21 9427749 Q02779 Q00610 MAP3K10 CLTC 0.21 12105200 Q02779 Q02779 MAP3K10 MAP3K10 0.332 11278395 Q05193 Q02779 DNM1 MAP3K10 0.309 9742220 Q13562 Q02779 NEUROD1 MAP3K10 0.623 12881483 Q9P2E2 Q02779 KIF17 MAP3K10 0.309 9427749 Q9Y496 Q02779 KIF3A MAP3K10 0.454 9427749 Q16539 Q02779 MAPK14 MAP3K10 0.309 11278395

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 HGS MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database MAPK1 MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database GARS MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database ABL2 MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database HTT MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database MAPK9 MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database MAP2K4 MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database CDC42 MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database COPS2 MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database YWHAE MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database RAC1 MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database DLG4 MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database HPCA MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database CLTC MAP3K10 MI:0045 experimental interaction detection MI:0461 interaction database MAP3K10 DNM1 MI:0045 experimental interaction detection MI:0461 interaction database MAP3K10 MAPK8IP2 MI:0045 experimental interaction detection MI:0461 interaction database MAP3K10 NEUROD1 MI:0045 experimental interaction detection MI:0461 interaction database MAP3K10 MAPK14 MI:0045 experimental interaction detection MI:0461 interaction database MAP3K10 MLK4 MI:0045 experimental interaction detection MI:0461 interaction database MAP3K10 KIFAP3 MI:0045 experimental interaction detection MI:0461 interaction database MAP3K10 CNKSR1 MI:0045 experimental interaction detection MI:0461 interaction database MAP3K10 KIF17 MI:0045 experimental interaction detection MI:0461 interaction database MAP3K10 MAPK8IP1 MI:0045 experimental interaction detection MI:0461 interaction database MAP3K10 KIF3A MI:0045 experimental interaction detection MI:0461 interaction database