PTM - CPLM Gene Name UniProt ID Type Position Code LATS1; WARTS O95835 Ubiquitination 1005 K LATS1; WARTS O95835 Ubiquitination 688 K LATS1; WARTS O95835 Ubiquitination 860 K

PTM - dbPAF Gene Name UniProt ID Position Type Species LATS1; WARTS O95835 1012 T Homo sapiens(Human) LATS1; WARTS O95835 1049 S Homo sapiens(Human) LATS1; WARTS O95835 1060 T Homo sapiens(Human) LATS1; WARTS O95835 1076 Y Homo sapiens(Human) LATS1; WARTS O95835 1079 T Homo sapiens(Human) LATS1; WARTS O95835 1104 S Homo sapiens(Human) LATS1; WARTS O95835 1107 S Homo sapiens(Human) LATS1; WARTS O95835 1111 S Homo sapiens(Human) LATS1; WARTS O95835 143 Y Homo sapiens(Human) LATS1; WARTS O95835 17 T Homo sapiens(Human) LATS1; WARTS O95835 171 S Homo sapiens(Human) LATS1; WARTS O95835 177 S Homo sapiens(Human) LATS1; WARTS O95835 181 S Homo sapiens(Human) LATS1; WARTS O95835 204 S Homo sapiens(Human) LATS1; WARTS O95835 23 Y Homo sapiens(Human) LATS1; WARTS O95835 244 S Homo sapiens(Human) LATS1; WARTS O95835 246 T Homo sapiens(Human) LATS1; WARTS O95835 255 T Homo sapiens(Human) LATS1; WARTS O95835 26 S Homo sapiens(Human) LATS1; WARTS O95835 261 T Homo sapiens(Human) LATS1; WARTS O95835 262 T Homo sapiens(Human) LATS1; WARTS O95835 27 S Homo sapiens(Human) LATS1; WARTS O95835 277 Y Homo sapiens(Human) LATS1; WARTS O95835 278 S Homo sapiens(Human) LATS1; WARTS O95835 283 Y Homo sapiens(Human) LATS1; WARTS O95835 289 S Homo sapiens(Human) LATS1; WARTS O95835 334 S Homo sapiens(Human) LATS1; WARTS O95835 335 S Homo sapiens(Human) LATS1; WARTS O95835 336 S Homo sapiens(Human) LATS1; WARTS O95835 394 S Homo sapiens(Human) LATS1; WARTS O95835 42 S Homo sapiens(Human) LATS1; WARTS O95835 462 S Homo sapiens(Human) LATS1; WARTS O95835 464 S Homo sapiens(Human) LATS1; WARTS O95835 490 T Homo sapiens(Human) LATS1; WARTS O95835 573 Y Homo sapiens(Human) LATS1; WARTS O95835 575 S Homo sapiens(Human) LATS1; WARTS O95835 580 S Homo sapiens(Human) LATS1; WARTS O95835 611 T Homo sapiens(Human) LATS1; WARTS O95835 612 T Homo sapiens(Human) LATS1; WARTS O95835 613 S Homo sapiens(Human) LATS1; WARTS O95835 616 T Homo sapiens(Human) LATS1; WARTS O95835 633 S Homo sapiens(Human) LATS1; WARTS O95835 635 S Homo sapiens(Human) LATS1; WARTS O95835 674 S Homo sapiens(Human) LATS1; WARTS O95835 792 S Homo sapiens(Human) LATS1; WARTS O95835 864 S Homo sapiens(Human) LATS1; WARTS O95835 872 S Homo sapiens(Human) LATS1; WARTS O95835 909 S Homo sapiens(Human) LATS1; WARTS O95835 967 T Homo sapiens(Human)

PTM - PhosSNP Gene Name dbSNP ID Gene Mutation AA Mutation Mutation Position Code Peptide Score Modification Type LATS1; WARTS rs56149740 CCA->CAA P->Q 244 S PPPPQVRSVTPPPPP 244 Phosphorylation TypeIII-

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O95835 R243-m1 Methylation PPPPPQVrsVtPPPP O95835 R252-m1 Methylation VtPPPPPrGQtPPPr O95835 R259-m1 Methylation rGQtPPPrGttPPPP O95835 K275-m1 Methylation WEPNSQTkRysGNME O95835 T17-p Phosphorylation YRQMRPKtFPASNyT O95835 Y23-p Phosphorylation KtFPASNyTVssRQM O95835 S26-p Phosphorylation PASNyTVssRQMLQE O95835 S27-p Phosphorylation ASNyTVssRQMLQEI O95835 S37-p Phosphorylation MLQEIREsLRNLsKP O95835 S42-p Phosphorylation REsLRNLsKPSDAAK O95835 S84-p Phosphorylation ALQEIRNsLLPFANE O95835 Y143-p Phosphorylation EFISKMSyQDPRREQ O95835 S171-p Phosphorylation KPGNVQQsVNRKQsW O95835 S177-p Phosphorylation QsVNRKQsWKGsKES O95835 S181-p Phosphorylation RKQsWKGsKESLVPQ O95835 S244-p Phosphorylation PPPPQVrsVtPPPPP O95835 T246-p Phosphorylation PPQVrsVtPPPPPrG O95835 T255-p Phosphorylation PPPPrGQtPPPrGtt O95835 T261-p Phosphorylation QtPPPrGttPPPPSW O95835 T262-p Phosphorylation tPPPrGttPPPPSWE O95835 Y277-p Phosphorylation PNSQTkRysGNMEyV O95835 S278-p Phosphorylation NSQTkRysGNMEyVI O95835 Y283-p Phosphorylation RysGNMEyVISRISP O95835 S336-p Phosphorylation PIIMQSSsKFNFPSG O95835 S462-p Phosphorylation QPNIPVRsNsFNNPL O95835 S464-p Phosphorylation NIPVRsNsFNNPLGN O95835 T490-p Phosphorylation ATTVTAItPAPIQQP O95835 S580-p Phosphorylation YESISKPsKEDQPSL O95835 S596-p Phosphorylation KEDESEKsYENVDSG O95835 T612-p Phosphorylation KEKKQITtsPItVRK O95835 S613-p Phosphorylation EKKQITtsPItVRKN O95835 T616-p Phosphorylation QITtsPItVRKNKKD O95835 S633-p Phosphorylation RRESRIQsYsPQAFK O95835 S635-p Phosphorylation ESRIQsYsPQAFKFF O95835 S674-p Phosphorylation EMMRVGLsQDAQDQM O95835 S792-p Phosphorylation IPGGDMMsLLIRMGI O95835 S864-p Phosphorylation HDSKYYQsGDHPRQD O95835 S872-p Phosphorylation GDHPRQDsMDFSNEW O95835 S909-p Phosphorylation HQRCLAHsLVGTPNY O95835 T967-p Phosphorylation MKVINWQtSLHIPPQ O95835 S982-p Phosphorylation AKLSPEAsDLIIKLC O95835 T1012-p Phosphorylation KAHPFFKtIDFSSDL O95835 S1049-p Phosphorylation VDPDKLWsDDNEEEN O95835 T1060-p Phosphorylation EEENVNDtLNGWYKN O95835 Y1076-p Phosphorylation KHPEHAFyEFtFRRF O95835 T1079-p Phosphorylation EHAFyEFtFRRFFDD O95835 S1107-p Phosphorylation EYINSQGsEQQsDED O95835 S1111-p Phosphorylation SQGsEQQsDEDDQNT O95835 K751-sm Sumoylation RNQVAHVkAERDILA O95835 K830-sm Sumoylation GFIHRDIkPDNILID

PTM - dbPTM UniProt ID Position Code Type Resources References O95835 181 S Phosphorylation Swiss-Prot 1010711 19369195 O95835 244 S Phosphorylation Swiss-Prot 1010711 15302935;19413330 O95835 246 T Phosphorylation Swiss-Prot 1010711 18669648;18691976;19369195;19413330 O95835 261 T Phosphorylation Swiss-Prot 1010711 19369195 O95835 277 Y Phosphorylation Swiss-Prot 1010711 17053785 O95835 278 S Phosphorylation Swiss-Prot 1010711 18669648 O95835 462 S Phosphorylation Swiss-Prot 1010711 19369195 O95835 464 S Phosphorylation Swiss-Prot 1010711 18669648;18691976;19369195;19413330;19690332;19927127 O95835 612 T Phosphorylation Swiss-Prot 1010711 19369195 O95835 613 S Phosphorylation Swiss-Prot 1010711 18691976;19369195 O95835 674 S Phosphorylation Swiss-Prot 1010711 17525332 O95835 909 S Phosphorylation Swiss-Prot 1010711 15688006 O95835 1079 T Phosphorylation Swiss-Prot 1010711 15688006 O95835 244 S Phosphorylation PhosphoELM.10011 15302935 O95835 278 S Phosphorylation PhosphoELM.10011 18669648;18220336 O95835 464 S Phosphorylation PhosphoELM.10011 18669648;15302935 O95835 633 S Phosphorylation PhosphoELM.10011 15688006 O95835 674 S Phosphorylation PhosphoELM.10011 17525332 O95835 909 S Phosphorylation PhosphoELM.10011 15688006 O95835 1111 S Phosphorylation PhosphoELM.10011 15688006 O95835 613 S Phosphorylation PhosphoELM.10011 15688006;12372621 O95835 246 T Phosphorylation PhosphoELM.10011 18669648 O95835 1079 T Phosphorylation PhosphoELM.10011 15688006 O95835 1049 S Phosphorylation Phosphositeplus.1010730 15688006 O95835 1111 S Phosphorylation Phosphositeplus.1010730 15688006 O95835 177 S Phosphorylation Phosphositeplus.1010730 20363803 O95835 181 S Phosphorylation Phosphositeplus.1010730 19369195;20363803 O95835 244 S Phosphorylation Phosphositeplus.1010730 15302935 O95835 278 S Phosphorylation Phosphositeplus.1010730 17494752;18220336;18669648;19690332 O95835 464 S Phosphorylation Phosphositeplus.1010730 14729942;15144186;18669648;18691976;19369195;19690332;19927127;20363803;21659604;22115753 O95835 613 S Phosphorylation Phosphositeplus.1010730 12372621;15688006;18691976;19276368;19369195;20363803;21659604 O95835 633 S Phosphorylation Phosphositeplus.1010730 15688006 O95835 674 S Phosphorylation Phosphositeplus.1010730 15688006;17525332 O95835 872 S Phosphorylation Phosphositeplus.1010730 15688006 O95835 909 S Phosphorylation Phosphositeplus.1010730 15688006;18328708;21666719 O95835 1012 T Phosphorylation Phosphositeplus.1010730 15688006 O95835 1060 T Phosphorylation Phosphositeplus.1010730 15688006 O95835 1079 T Phosphorylation Phosphositeplus.1010730 15688006;18328708 O95835 17 T Phosphorylation Phosphositeplus.1010730 20736484 O95835 246 T Phosphorylation Phosphositeplus.1010730 18669648;18691976;19369195;19664995;20363803;21659604 O95835 255 T Phosphorylation Phosphositeplus.1010730 20363803 O95835 490 T Phosphorylation Phosphositeplus.1010730 12372621 O95835 612 T Phosphorylation Phosphositeplus.1010730 19276368 O95835 967 T Phosphorylation Phosphositeplus.1010730 15688006 O95835 277 Y Phosphorylation Phosphositeplus.1010730 17053785;19690332 O95835 283 Y Phosphorylation Phosphositeplus.1010730 18180459;20007894;21403953;21447384 O95835 244 S Phosphorylation HPRD 9.0 19413330 O95835 278 S Phosphorylation HPRD 9.0 18669648 O95835 334 S Phosphorylation HPRD 9.0 17322306 O95835 335 S Phosphorylation HPRD 9.0 17322306 O95835 462 S Phosphorylation HPRD 9.0 18691976,19651622,18452278 O95835 464 S Phosphorylation HPRD 9.0 17322306,18669648,19413330,18691976,19651622 O95835 613 S Phosphorylation HPRD 9.0 12372621,18691976 O95835 674 S Phosphorylation HPRD 9.0 17525332 O95835 1111 S Phosphorylation HPRD 9.0 18691976 O95835 246 T Phosphorylation HPRD 9.0 18669648,19413330,18691976,19664995 O95835 261 T Phosphorylation HPRD 9.0 18691976 O95835 611 T Phosphorylation HPRD 9.0 18691976 O95835 613 S Phosphorylation (CDK1) HPRD 9.0 12372621,18691976 O95835 490 T Phosphorylation (CDK1) HPRD 9.0 12372621 O95835 278 S Phosphorylation SysPTM 1.1 17494752;18669648 O95835 464 S Phosphorylation SysPTM 1.1 18669648;18691976 O95835 613 S Phosphorylation SysPTM 1.1 18691976 O95835 246 T Phosphorylation SysPTM 1.1 18669648;18691976

PTM - HPRD Symbol Position Code Type References LATS1 1111 S Phosphorylation 18691976 LATS1 244 S Phosphorylation 19413330 LATS1 246 T Phosphorylation 18669648,19413330,18691976,19664995 LATS1 261 T Phosphorylation 18691976 LATS1 278 S Phosphorylation 18669648 LATS1 334 S Phosphorylation 17322306 LATS1 335 S Phosphorylation 17322306 LATS1 462 S Phosphorylation 18691976,19651622,18452278 LATS1 464 S Phosphorylation 17322306,18669648,19413330,18691976,19651622 LATS1 490 T Phosphorylation 12372621 LATS1 611 T Phosphorylation 18691976 LATS1 613 S Phosphorylation 12372621,18691976 LATS1 674 S Phosphorylation 17525332

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type O95835 909 S 15688006 LTP Phosphorylation O95835 464 S 18669648 HTP Phosphorylation O95835 464 S 15302935 HTP Phosphorylation O95835 1079 T 15688006 LTP Phosphorylation O95835 674 S 17525332 HTP Phosphorylation O95835 278 S 18669648 HTP Phosphorylation O95835 278 S 18220336 HTP Phosphorylation O95835 633 S 15688006 LTP Phosphorylation O95835 613 S 15688006 LTP Phosphorylation O95835 613 S 12372621 CDK1 LTP Phosphorylation O95835 1111 S 15688006 LTP Phosphorylation O95835 246 T 18669648 HTP Phosphorylation O95835 244 S 15302935 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs O95835 246 Phosphothreonine 18669648;23186163 O95835 278 Phosphoserine 18669648 O95835 464 Phosphoserine; by NUAK1 and NUAK2 18669648;23186163;19927127 O95835 613 Phosphoserine 23186163 O95835 674 Phosphoserine 17525332 O95835 909 Phosphoserine; by STK3/MST2 15688006 O95835 1079 Phosphothreonine; by STK3/MST2 15688006;28087714

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type LATS1 IPI00005858 S 181 KQSWKGpSKESLVP phosphorylation LATS1 IPI00005858 S 464 IPVRSNpSFNNPLG phosphorylation LATS1 IPI00005858 S 613 KKQITTpSPITVRK phosphorylation LATS1 IPI00005858 T 246 PQVRSVpTPPPPPR phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 9113 114563 - K Ubiquitination 21212414 9113 114563 - K Ubiquitination 21139048