PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CORO1A TRAF7 26186194 biogrid exp G G G G GP G G G G G G G G G GP G G G G G G G G TRAF7 IFT57 26186194 biogrid exp GP GP G G G GP G GP GP G GP P GP G G GP GP G G G G G GP GP GP G GP GP G FAM175B TRAF7 26186194 biogrid exp GP GP G G G GP G G GP G GP G GP G G GP GP G G G G G GP G GP G GP GP G ODF2 TRAF7 26638075 biogrid,intact exp P P P P P GP OIP5 TRAF7 26186194 biogrid exp GP G G G P GP P GP G G GP G GP GP GP TRAF7 LCA5 26638075 biogrid,intact exp G G G G G GP G GP GP G GP G G G G GP GP G G G G G G G GP G GP G G CCDC67 TRAF7 26186194 biogrid exp P P P P P P P P P P G G P P P P GP RIPK4 TRAF7 21903422 innatedb,biogrid exp G P P GP G GP GP GP G G P G G G G G G G GP GP TRAF7 TRAF7 14743216 hprd,i2d,intact exp GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 RALYL 26186194 biogrid exp GP G GP G P G GP GP G G TRAF7 RGCC 26186194 biogrid exp GP GP G G G GP G GP GP G GP P GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 CLEC11A 26186194 biogrid exp GP G G G G GP G G GP G GP GP GP G G GP GP G G G G G GP GP G GP GP G TRAF7 LIME1 26186194 biogrid exp P P P P P P P P P P P P P P TRAF7 DTNBP1 26186194 biogrid exp GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G SP6 TRAF7 26186194 biogrid exp GP GP G G P P GP P P GP G G P P G G G G GP GP P G P P G TRAF7 MAP3K2 26496610, 25402006 biogrid,intact exp, pred G GP G G G GP G GP GP G GP GP G G G GP GP G G G G G GP GP GP G GP GP G UBE2D2 TRAF7 19549727, 23023127 biogrid,intact exp, pred GP G G G G GP G G GP G GP GP GP G G G GP G G G G G G GP G G GP GP G UBE2D1 TRAF7 19549727, 23023127 biogrid,intact exp, pred GP G G G G GP G G GP G GP GP GP G G G GP G G G G G G GP G G GP GP G TRAF7 MAP3K3 14743216,15001576, 25402006, 21836163 hprd,biogrid,mint,intact exp, pred G G G G G GP G GP G G GP G GP G G GP GP G G G G G G G GP G GP G G UBE2K TRAF7 19549727, 23023127 biogrid,intact exp, pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 UBE2D4 19549727, 23023127 biogrid,intact exp, pred GP G G G G GP G G GP G GP GP GP G G G GP G G G G G G GP G G GP GP G TRAF7 FBXW11 25900982, 21836163 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2L6 TRAF7 19549727, 23023127 biogrid,intact exp, pred GP GP G G G GP G G GP G GP GP GP G G GP GP G G G G G GP G GP G GP GP G UBE2L3 TRAF7 19549727, 23023127 biogrid,intact exp, pred GP G G G G GP G GP GP G GP G G G G GP GP G G G G G GP GP GP G GP GP G TRAF7 CYLD 16230348, 21836163 hprd exp, pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G GP GP GP G GP GP TRAF7 TRAF6 16230348, 25402006, 23023127 hprd exp, pred GP GP G G G G G GP GP G GP GP GP G G GP G G G G G G GP G GP G GP GP G YWHAE TRAF7 ortho GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G MYB TRAF7 21836163 ortho, pred P P G G P P GP P P GP G G GP P G G GP P GP GP P G UBE4A TRAF7 23023127, 21836163 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G UBE2E1 TRAF7 23023127 pred GP GP G G G GP G G GP G GP G G G G GP GP G G G G G G GP GP G GP GP G UBE2B TRAF7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF7 FEM1B 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G WWP2 TRAF7 21836163 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G DGKI TRAF7 23023127 pred G G G P G G GP UBE2H TRAF7 23023127 pred GP GP G G G GP G GP G G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G PPP5C TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G SCO2 TRAF7 25402006 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G G G G G GP G GP G GP GP G TRAF7 AKAP8L 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G RGS19 TRAF7 23023127 pred GP GP G G G GP G G GP G GP GP GP G G G GP G G G G G GP GP G G GP GP G TRAF7 ZDHHC13 23023127 pred G G G G G G G G G G G GP G G G G G G G G G G G G G GP GP G UBE2N TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 RNF31 23023127 pred P P G G G GP P P G GP GP GP GP GP G G G P GP GP G P GP TRAF7 STUB1 25402006, 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G RGS9 TRAF7 23023127 pred G G G G G G G G TRAF7 UBE2T 23023127 pred G G G GP G GP P P GP GP G G GP P GP G AR TRAF7 23023127 pred GP G G G G G G G G G G G G G G G G G G G G G G G GP G TRAF7 RLIM 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRIM21 TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 IKBKG 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF7 RQCD1 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 UBE2F 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 CPVL 25402006 pred G G G G G G G GP G G GP G GP G G G G G G G G G G G G G G GP G PKN1 TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 RNF5 23023127 pred GP GP G G G GP G G GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 MIB1 21836163 pred GP GP G G G GP G G GP G GP GP G G G GP GP G G G G G GP G GP G GP GP G TRAF7 PFDN2 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G RNF20 TRAF7 21836163 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G CUL4A TRAF7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GADD45G TRAF7 23023127 pred GP G G G P G GP GP G G G G G G P G G G G G G GP G G GP G PFDN1 TRAF7 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 UBE2R2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G GP G G TRAF7 PDRG1 25402006 pred G GP G G G GP G GP GP G GP G GP G G GP GP G G G G G G GP GP G GP GP G ST13 TRAF7 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G UBE2V2 TRAF7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G IKBKB TRAF7 25402006 pred GP GP G G G GP G G GP G GP G GP G G GP GP G G G G G GP G GP G GP GP G TRAF7 RNF2 23023127 pred P P P GP P P P P P P P P P PHGDH TRAF7 25402006 pred GP G G G G GP G G GP G GP GP GP G G GP GP G G G G G GP G GP G GP GP G RHOC TRAF7 23023127 pred P G P G P P G TRAF7 UACA 25402006 pred G GP G G G GP G G GP G GP G G G G GP GP G G G G G GP G GP G GP GP G TRAF7 ST13P4 25402006 pred TRAF7 ASAP3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G GP GP G DCAF10 TRAF7 23023127 pred G G G G G GP G GP G G G G GP G G G GP G G G G G G GP G G GP G G DBN1 TRAF7 25402006 pred G G G G G GP G G GP G GP G G G G GP G G G G GP G G G GP GP G YWHAQ TRAF7 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP G GP G GP GP G TRAF7 WDR53 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G GP GP GP G GP GP ILK TRAF7 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G G G G G GP GP GP G GP GP G XPOT TRAF7 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G G GP GP G G GP G TRAF7 BIRC7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G GP GP GP G GP GP G PFDN6 TRAF7 25402006 pred GP GP G G G GP G GP GP G GP G G G G GP GP G G G G G GP GP GP G GP GP G GNAI2 TRAF7 25402006, 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G LGALS7, LGALS7B TRAF7 25402006 pred P TRAF7 FANCL 21836163 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G VBP1 TRAF7 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 DNAJC7 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 CAND1 23023127 pred G GP G G G G G G GP G GP GP G G G GP G G G G G G GP GP GP G G GP G TRAF7 DNAJB4 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G AXIN1 TRAF7 23023127 pred GP GP G G GP G P GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 WWP1 21836163 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G UBE2S TRAF7 23023127 pred G G G G G G G G GP G G G G G G G G G G G G G G G GP G S100A7 TRAF7 25402006 pred GP G TGFB1I1 TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 CORO1C 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 RNF115 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DLG1 TRAF7 25402006 pred GP GP G G G GP G G GP G GP G GP G G GP GP G G G G G GP G GP G GP GP G CAPZB TRAF7 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 RNF144B 23023127, 21836163 pred G GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G G G GP G G GP G TRAF7 MAP4K1 23023127 pred G G G G G G G G G G GP G G G G G GP G G G G TRAF7 LYST 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF7 BAG5 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TGFB1 TRAF7 23023127 pred G G G G G G G G G G G G G G G GP G G G G G G G GP G GP G G PRKD3 TRAF7 23023127 pred G GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 TUBB6 25402006 pred GP GP G G G GP G G GP G GP GP GP G G GP GP G G G G G GP G GP G GP GP G NEDD4 TRAF7 23023127 pred GP GP G G P G GP GP GP G GP G G GP GP G G G G G GP GP GP G GP P G TRAF7 DNAJA3 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G UBE2I TRAF7 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G G G G G GP G GP G GP GP G CUL4B TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP G G G GP GP G G G G G GP GP GP G GP GP G CDKN2A TRAF7 23023127 pred G GP G G G GP G G G G G G GP G G G GP G G G G G G G G G GP G G UBE2G2 TRAF7 23023127 pred GP GP G G G GP G G GP G GP GP GP G G GP GP G G G G G G G GP G GP GP G GNAI3 TRAF7 23023127 pred G GP G G G GP G GP GP G G G GP G G GP GP G G G G G G G GP G GP GP G CUL1 TRAF7 23023127 pred GP G G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 PPP1R27 23023127 pred GP G G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 MAP3K5 25402006 pred G GP G G G GP G G GP G GP G GP G G G GP G G G G G G G G G GP GP G DCAF8 TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G YWHAB TRAF7 25402006 pred GP GP G G G GP G G GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G CDC20 TRAF7 23023127 pred P G G G GP P GP G G P GP GP GP PYGM TRAF7 25402006 pred G G GP G G GP G P P G G G GP G G G GP GP G G GP G RNF4 TRAF7 23023127 pred GP G G G G GP G GP GP G GP G G G G G GP G G G G G GP GP G G GP GP G GNAQ TRAF7 23023127 pred GP GP G G G GP G G GP G GP GP G G G GP GP G G G G G G G GP G GP GP G TAB1 TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G GP GP GP G GP GP G TRAF7 VAV3 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G CDKN2C TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G GP GP GP G GP GP G TRAF7 DTX3L 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 RNF7 23023127 pred GP GP G G G GP G G GP G GP GP G G G GP GP G G G G G G G GP G GP GP G RING1 TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G UBE2G1 TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G SQSTM1 TRAF7 23023127 pred GP GP G G G G G G GP G GP GP GP G G GP G G G G G G GP GP GP G GP GP G TRAF7 ZDHHC17 23023127 pred G GP G G G GP G G GP G GP GP GP G G GP GP G G G G G GP G GP G GP GP G LRP1 TRAF7 23023127 pred G G G G G GP G G G G G GP GP G G G GP G G G G G G G G G G GP G TRAF7 SMURF2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CAPZA1 TRAF7 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G UBE2V1 TRAF7 23023127 pred TRAF7 CUL5 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G LYN TRAF7 23023127 pred GP G G G G GP G G GP G G G GP G G GP GP G G G G G GP GP G GP G G GNA13 TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G CD74 TRAF7 23023127 pred GP GP G G G GP G G GP G GP GP GP G G GP GP G G G G G GP G GP G GP GP G UBL4A TRAF7 25402006 pred GP GP G G G GP G G GP G GP G G G G G GP G G G G G G G G G GP P G TRAF7 MLST8 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 LNX1 21836163 pred GP G G GP G GP GP G GP GP GP G G GP GP G G G G G GP G GP GP GP TRAF7 NUDC 25402006 pred GP GP G G G GP G G GP G GP GP GP G G GP GP G G G G G GP G GP G GP GP G NOTCH2 TRAF7 23023127 pred G GP G G G G G G GP G G G G G G G G G G G G G G G G G GP G G ERCC8 TRAF7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RHOH TRAF7 23023127 pred GP P G G P P GP P GP GP G G GP P G G GP GP G GP P G TRAF7 BARD1 23023127 pred P G G P P GP P P P G G GP P G G P GP P G GP GP G RAG1 TRAF7 23023127 pred MAP2K5 TRAF7 25402006 pred GP GP G G G GP G GP GP G GP P GP G G GP GP G G G GP GP GP G GP GP G CSF2 TRAF7 23023127 pred G G G G G G G G TRAF7 MYLIP 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF7 PJA1 21836163 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G G G G G GP GP GP G GP GP G EIF3I TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 WWC1 23023127 pred GP GP G G G GP G G GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 DDB2 23023127 pred GP GP G G G GP G G GP G GP GP GP G G GP GP G G G G G GP GP G GP GP G UBOX5 TRAF7 23023127 pred GP GP G G G GP G GP P G G G GP G G P GP G G G G G GP P GP G GP G G TUBB3 TRAF7 25402006 pred GP GP G G G GP G G GP G GP GP GP G G GP GP G G G G G GP G GP G GP GP G TRAF7 RNF25 21836163 pred P G P P P P P P P P P P G P P RIPK1 TRAF7 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G RFWD3 TRAF7 23023127 pred G G G G G G G G G G G G G G G G G G SEC16A TRAF7 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 TFG 25402006, 23023127 pred G GP G G G GP G GP GP G GP G G G G GP GP G G G G G GP G GP G GP GP G TRAF7 CHFR 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GNAT1 TRAF7 23023127 pred TRAF7 ASB6 23023127 pred GP GP G G G GP G P GP G GP P GP G G GP GP G G G G G GP P GP G GP GP G UBE2M TRAF7 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 FZR1 23023127 pred G GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP G GP GP G UBE2A TRAF7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF151 TRAF7 23023127 pred P G G G GP GP GP GP G G GP G G GP G G GP TRAF7 BRAP 21836163 pred P P G G P GP P P P P G GP P G G GP GP GP P GP UBE2NL TRAF7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRAF7 UBE2E2 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G BIRC2 TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G DCAF12 TRAF7 23023127 pred G G G G G GP G G GP G G G GP G G GP GP G G G G G GP GP GP G GP G G SORBS3 TRAF7 23023127 pred G G G G G GP G GP GP G GP GP G G G GP GP G G G G G GP GP GP G GP G G TRAF7 RPS27L 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GADD45B TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G RGS3 TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 SMURF1 23023127 pred G GP G G G GP G G GP G GP G GP G G G GP G G G G G G G G G G GP G GNB2L1 TRAF7 23023127 pred P P P P P P P P P P P P TRAF7 UBE2E3 23023127 pred GP GP G G G GP G G GP G GP G G G G GP GP G G G G G G GP GP G GP GP G CDKN2B TRAF7 23023127 pred GP P GP P P G G GP G GP G CDC34 TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G GNB2 TRAF7 23023127 pred G GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP G GP G GP GP G BRCA1 TRAF7 23023127 pred P P G G P P P P P P GP P P P P P GP TRAF7 RNF135 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 PIH1D1 25402006 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G MID1 TRAF7 23023127 pred G G G GP G GP GP G GP G G G G GP GP G G G G G G GP GP G GP GP G ITGB3 TRAF7 23023127 pred GP G G G G GP G GP G G GP G GP G G G GP G G G G G G G G G GP G TRAF7 PFDN4 25402006 pred GP GP G G G GP G G GP G GP G GP G G GP GP G G G G G G GP GP G GP GP G TRAF7 TRIM11 21836163 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP P GP G GP GP G MYO1B TRAF7 25402006 pred GP G G G G GP G G GP G GP GP GP G G GP GP G G G G G GP G GP G GP GP G TRAF7 ANAPC11 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G G G G G GP GP GP G GP GP G UBE2D3 TRAF7 23023127 pred GP G G G G GP G G GP G GP GP GP G G G GP G G G G G G GP G G GP GP G UBE2C TRAF7 23023127 pred GP GP G G G GP G GP GP G GP GP GP G G GP GP G G G G G GP GP GP G GP GP G TRAF7 LRSAM1 21836163 pred P GP G GP G P GP G GP GP P G P GP G G G G P P P G P P G TRAF7 SCIN 25402006 pred P G P G GP GP GP G G GP GP BMI1 TRAF7 23023127 pred P P P P P P P P P P P P P P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q6Q0C0 - 14743216 - C 15 Q6Q0C0 - 14743216 - C 16 Q6Q0C0 Q6Q0C0 - 14743216 - X 2 Q6Q0C0 A0A087WW00 two hybrid 19549727 direct interaction X 2 Q6Q0C0 A0A024R1A4 two hybrid 19549727 direct interaction X 2 Q6Q0C0 P61086 two hybrid 19549727 direct interaction X 2 Q6Q0C0 Q99759 affinity chromatography technology 15001576 physical association X 2 Q6Q0C0 P0CG48 affinity chromatography technology 21963094 physical association X 2 Q6Q0C0 P0CG48 affinity chromatography technology 23000965 physical association X 2 Q6Q0C0 Q99759 affinity chromatography technology 14743216 physical association X 2 Q6Q0C0 O14933-2 two hybrid 19549727 direct interaction X 2 Q6Q0C0 P62837 two hybrid 19549727 direct interaction X 2 Q6Q0C0 A0A024RA90 two hybrid 19549727 direct interaction X 2 Q6Q0C0 affinity chromatography technology 21903422 physical association X 2 Q6Q0C0 pull down 21903422 direct interaction X 2 Q6Q0C0 P0CG48 affinity chromatography technology 21139048 physical association X 2 Q6Q0C0 P0CG48 affinity chromatography technology 21890473 physical association X 2 Q6Q0C0 P0CG48 affinity chromatography technology 21906983 physical association X 2 Q6Q0C0 tandem affinity purification 14743216 association C 16 Q8N2W9 Q6Q0C0 coimmunoprecipitation 15251447 physical association X 2 Q6Q0C0 Q6Q0C0 anti tag coimmunoprecipitation 14743216 physical association X 2 Q6Q0C0 A0A024R1A4 two hybrid array 19549727 physical association X 2 Q6Q0C0 Q81ZE0 two hybrid pooling approach 20711500 physical association X 2 Q6Q0C0 Q9ERK0 anti tag coimmunoprecipitation 21903422 physical association X 2 Q6Q0C0 Q9ERK0 anti tag coimmunoprecipitation 21903422 physical association X 2 O14933 Q6Q0C0 two hybrid array 19549727 physical association X 2 Q6Q0C0 Q99759 tandem affinity purification 14743216 physical association X 2 Q6Q0C0 Q99759 anti tag coimmunoprecipitation 14743216 physical association X 2 Q6Q0C0 Q99759 imaging technique 14743216 colocalization X 2 Q6Q0C0 Q99759 coimmunoprecipitation 15001576 physical association X 2 Q6Q0C0 B3KSH4 two hybrid array 19549727 physical association X 2 Q6Q0C0 A0A024QZJ2 two hybrid array 19549727 physical association X 2 Q6Q0C0 P62837 two hybrid array 19549727 physical association X 2 Q6Q0C0 A0A024RA90 two hybrid array 19549727 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBE2D1 TRAF7 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101241|BIOGRID_124284 bait|bait prey|prey TRAF7 PIAS4 MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation) 15251447 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0471(mint) UniProt_79232|MINT_55526|MINT_58321 prey|prey|prey bait|bait|bait TRAF7 MAP3K3 MI:0019(coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 14743216,15001576 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association) (intact)|MI:0471(mint)|(intact)|(biogrid)|(biogrid)|(intact)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(intact)|MI:0471(mint) UniProt_74333|MINT_86730|UniProt_74381|BIOGRID_83650|BIOGRID_214514|UniProt_75939|MINT_53892|HPRD_20207|MINT_53167|UniProt_74383|MINT_87506 bait|prey|bait|prey|bait|prey|prey|-|prey|neutral component|prey prey|bait|prey|bait|prey|bait|bait|-|bait|neutral component|bait TRAF7 HIP2 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_101209 prey bait RIPK4 TRAF7 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21903422 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_155727|BIOGRID_155969 bait|bait prey|prey UBE2D2 TRAF7 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101263|BIOGRID_124285 bait|bait prey|prey UBE2L3 TRAF7 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124287|UniProt_101382 bait|bait prey|prey TRAF7 TRAF6 MI:0493(in vivo) 16230348 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25595 - - TRAF7 UBE2D4 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_101463|BIOGRID_124286 prey|prey bait|bait CSNK1E TRAF7 MI:0004(affinity chromatography technology) 23455922 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_277264 bait prey UBC TRAF7 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21139048,21890473,21906983,21963094,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_264184|BIOGRID_180606|BIOGRID_171459|BIOGRID_176145|BIOGRID_267855 bait|bait|bait|bait|bait prey|prey|prey|prey|prey UBE2K TRAF7 MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_124288 bait prey UBE2L6 TRAF7 MI:0018(two hybrid)|MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124038|UniProt_101128 bait|bait prey|prey TRAF7 CYLD MI:0493(in vivo) 16230348 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25742 - -

PPI - HINT Gene A Gene B PMID Method Quality OIP5 TRAF7 26186194 0004 HT CORO1A TRAF7 26186194 0004 HT CCDC67 TRAF7 26186194 0004 HT FAM175B TRAF7 26186194 0004 HT SP6 TRAF7 26186194 0004 HT ODF2 TRAF7 26638075,26638075 1314,1313 HT TRAF7 TRAF7 14743216,14743216,14743216 0045,0007,0019 HT TRAF7 RALYL 26186194 0004 HT TRAF7 LCA5 26638075,26638075 0004,0007 HT TRAF7 DTNBP1 26186194 0004 HT TRAF7 MAP3K3 14743216,14743216,14743216,15001576,15001576,14743216,14743216 0428,0007,0019,0004,0019,0004,0676 HT,LC TRAF7 LIME1 26186194 0004 HT TRAF7 RGCC 26186194 0004 HT TRAF7 IFT57 26186194 0004 HT TRAF7 CLEC11A 26186194 0004 HT TRAF7 MAP3K2 26496610,26496610 0007,0004 HT OIP5 TRAF7 26186194 0004 HT CORO1A TRAF7 26186194 0004 HT CCDC67 TRAF7 26186194 0004 HT FAM175B TRAF7 26186194 0004 HT SP6 TRAF7 26186194 0004 HT ODF2 TRAF7 26638075,26638075 1314,1313 HT TRAF7 TRAF7 14743216,14743216,14743216 0045,0007,0019 HT TRAF7 RALYL 26186194 0004 HT TRAF7 LCA5 26638075,26638075 0004,0007 HT TRAF7 DTNBP1 26186194 0004 HT TRAF7 MAP3K3 14743216,14743216,14743216,14743216,14743216 0428,0007,0019,0004,0676 HT TRAF7 LIME1 26186194 0004 HT TRAF7 RGCC 26186194 0004 HT TRAF7 IFT57 26186194 0004 HT TRAF7 CLEC11A 26186194 0004 HT TRAF7 MAP3K2 26496610,26496610 0007,0004 HT TRAF7 MAP3K3 15001576,15001576 0004,0019 LC HIP2 TRAF7 19549727 0397 HT UBE2L6 TRAF7 19549727,19549727 0397,0018 HT UBE2D1 TRAF7 19549727,19549727 0397,0018 HT UBE2K TRAF7 19549727 0018 HT UBE2D2 TRAF7 19549727,19549727 0397,0018 HT UBE2L3 TRAF7 19549727,19549727 0397,0018 HT TRAF7 TRAF7 14743216,14743216,14743216 0045,0007,0019 LC TRAF7 PIAS4 15251447 0019 LC TRAF7 MAP3K3 14743216,14743216,14743216,15001576,15001576,14743216,14743216 0428,0007,0019,0004,0019,0004,0676 LC TRAF7 UBE2D4 19549727,19549727 0397,0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q6Q0C0 B3KSH4 TRAF7 HIP2 0.126 19549727 Q6Q0C0 P61086 TRAF7 UBE2K 0.183 19549727 Q6Q0C0 O43482 TRAF7 OIP5 0.126 26186194 Q6Q0C0 Q05D60 TRAF7 CCDC67 0.126 26186194 Q9H4X1 Q6Q0C0 RGCC TRAF7 0.126 26186194 Q9NWB7 Q6Q0C0 IFT57 TRAF7 0.126 26186194 Q9H400 Q6Q0C0 LIME1 TRAF7 0.126 26186194 Q9Y240 Q6Q0C0 CLEC11A TRAF7 0.126 26186194 Q6Q0C0 P68036 TRAF7 UBE2L3 0.376 19549727 Q6Q0C0 Q6Q0C0 TRAF7 TRAF7 0.155 14743216 Q81ZE0 Q6Q0C0 AMPS TRAF7 0.126 20711500 Q9Y2X8 Q6Q0C0 UBE2D4 TRAF7 0.376 19549727 Q86SE5 Q6Q0C0 RALYL TRAF7 0.126 26186194 Q9Y2U5 Q6Q0C0 MAP3K2 TRAF7 0.236 26496610 Q6Q0C0 Q5BJF6 TRAF7 ODF2 0.236 26638075 Q6Q0C0 P51668 TRAF7 UBE2D1 0.286 19549727 Q6Q0C0 O14933 TRAF7 UBE2L6 0.286 19549727 Q6Q0C0 P62837 TRAF7 UBE2D2 0.286 19549727 Q86VQ0 Q6Q0C0 LCA5 TRAF7 0.236 26638075 Q6Q0C0 P31146 TRAF7 CORO1A 0.126 26186194 Q96EV8 Q6Q0C0 DTNBP1 TRAF7 0.126 26186194 Q99759 Q6Q0C0 MAP3K3 TRAF7 0.617 14743216,15001576 Q9ERK0 Q6Q0C0 RIPK4 TRAF7 0.236 21903422 Q9UKB1 Q6Q0C0 FBXW11 TRAF7 0.126 25900982 Q6Q0C0 Q15018 TRAF7 FAM175B 0.126 26186194 Q6Q0C0 Q01860 TRAF7 POU5F1 0.126 26687479 Q6Q0C0 Q3SY56 TRAF7 SP6 0.126 26186194

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 UBE2L6 TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database OIP5 TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database UBC TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database MYB TRAF7 MI:0362 inference MI:0461 interaction database TAF1 TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database CORO1A TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D1 TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database RIPK4 TRAF7 MI:0362 inference MI:0461 interaction database UBE2K TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D2 TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database UBE2L3 TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database POU5F1 TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database CCDC67 TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database FAM175B TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database SP6 TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database ODF2 TRAF7 MI:0045 experimental interaction detection MI:0461 interaction database TRAF7 RALYL MI:0045 experimental interaction detection MI:0461 interaction database TRAF7 LCA5 MI:0045 experimental interaction detection MI:0461 interaction database TRAF7 UBE2E3 MI:0362 inference MI:0461 interaction database TRAF7 DTNBP1 MI:0045 experimental interaction detection MI:0461 interaction database TRAF7 MAP3K3 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TRAF7 LIME1 MI:0045 experimental interaction detection MI:0461 interaction database TRAF7 RGCC MI:0045 experimental interaction detection MI:0461 interaction database TRAF7 IFT57 MI:0045 experimental interaction detection MI:0461 interaction database TRAF7 FBXW11 MI:0045 experimental interaction detection MI:0461 interaction database TRAF7 CLEC11A MI:0045 experimental interaction detection MI:0461 interaction database TRAF7 MAP3K2 MI:0045 experimental interaction detection MI:0461 interaction database TRAF7 UBE2D4 MI:0045 experimental interaction detection MI:0461 interaction database