PTM - CPLM Gene Name UniProt ID Type Position Code LLGL1; DLG4; HUGL; HUGL1 Q15334 Ubiquitination 19 K LLGL1; DLG4; HUGL; HUGL1 Q15334 Ubiquitination 27 K LLGL1; DLG4; HUGL; HUGL1 Q15334 Ubiquitination 293 K LLGL1; DLG4; HUGL; HUGL1 Q15334 Ubiquitination 1046 K LLGL1; DLG4; HUGL; HUGL1 Q15334 Ubiquitination 17 K LLGL1; DLG4; HUGL; HUGL1 Q15334 Ubiquitination 848 K LLGL1; DLG4; HUGL; HUGL1 Q15334 Ubiquitination 502 K LLGL1; DLG4; HUGL; HUGL1 Q15334 Ubiquitination 519 K LLGL1; DLG4; HUGL; HUGL1 Q15334 Ubiquitination 684 K LLGL1; DLG4; HUGL; HUGL1 Q15334 Ubiquitination 569 K LLGL1; DLG4; HUGL; HUGL1 Q15334 Ubiquitination 906 K LLGL1; DLG4; HUGL; HUGL1 Q15334 Ubiquitination 780 K LLGL1; DLG4; HUGL; HUGL1 Q15334 Ubiquitination 59 K

PTM - dbPAF Gene Name UniProt ID Position Type Species LLGL1; DLG4; HUGL; HUGL1 Q15334 1040 S Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 1041 S Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 420 S Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 488 S Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 509 Y Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 510 S Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 567 T Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 655 S Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 659 S Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 663 S Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 670 S Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 704 T Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 936 S Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 961 S Homo sapiens(Human) LLGL1; DLG4; HUGL; HUGL1 Q15334 967 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q15334 K657-m1 Methylation LSRVKsLkKsLRQsF Q15334 S488-p Phosphorylation TDCEHADsLAQAAED Q15334 Y509-p Phosphorylation kVGCFDPysDDPRLG Q15334 S510-p Phosphorylation VGCFDPysDDPRLGV Q15334 T526-p Phosphorylation kVALCKYtAQMVVAG Q15334 S553-p Phosphorylation VPVEQAVsVAIIDLL Q15334 T567-p Phosphorylation LQDREGFtWkGHERL Q15334 S655-p Phosphorylation GPLSRVKsLkKsLRQ Q15334 S659-p Phosphorylation RVKsLkKsLRQsFRR Q15334 S663-p Phosphorylation LkKsLRQsFRRIRKs Q15334 S670-p Phosphorylation sFRRIRKsRVSGKKR Q15334 T704-p Phosphorylation CPHDVEMtPVQRRIE Q15334 S961-p Phosphorylation PRDATQAsYRIREsP Q15334 S967-p Phosphorylation AsYRIREsPKLSQAN Q15334 S1040-p Phosphorylation DVKDFLGsSEEsEkN Q15334 S1044-p Phosphorylation FLGsSEEsEkNLRNL Q15334 K17-ub Ubiquitination GADPQREkLkQELFA Q15334 K19-ub Ubiquitination DPQREkLkQELFAFN Q15334 K27-ub Ubiquitination QELFAFNkTVEHGFP Q15334 K59-ub Ubiquitination GTRSGAVkIYGAPGV Q15334 K293-ub Ubiquitination FPCKAINkILWRNCE Q15334 K502-ub Ubiquitination DDWPPFRkVGCFDPy Q15334 K519-ub Ubiquitination DPRLGVQkVALCKYt Q15334 K569-ub Ubiquitination DREGFtWkGHERLSP Q15334 K906-ub Ubiquitination VHYSCIRkEDISGIA Q15334 K1046-ub Ubiquitination GsSEEsEkNLRNLAE

PTM - dbPTM UniProt ID Position Code Type Resources References Q15334 509 Y Phosphorylation Swiss-Prot 1010711 18083107 Q15334 663 S Phosphorylation Swiss-Prot 1010711 12725730 Q15334 704 T Phosphorylation Swiss-Prot 1010711 18691976 Q15334 19 K Ubiquitylation Phosphositeplus.1010730 21890473 Q15334 27 K Ubiquitylation Phosphositeplus.1010730 21890473 Q15334 293 K Ubiquitylation Phosphositeplus.1010730 21890473 Q15334 659 S Phosphorylation Phosphositeplus.1010730 20363803;21406692 Q15334 663 S Phosphorylation Phosphositeplus.1010730 20363803;21406692 Q15334 967 S Phosphorylation Phosphositeplus.1010730 21406692 Q15334 704 T Phosphorylation Phosphositeplus.1010730 18691976 Q15334 509 Y Phosphorylation Phosphositeplus.1010730 18083107;18180459;20090780;20736484 Q15334 936 S Phosphorylation SysPTM 1.1 17322306

PTM - UniProt UniProt ID Position Type PMIDs Q15334 663 Phosphoserine 12725730

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type LLGL1 IPI00105532 T 704 PHDVEMpTPVQRRI phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 3996 110183 - K Ubiquitination 20829363 3996 110183 - K Ubiquitination 21139048 3996 110183 - K Ubiquitination 21890473 3996 110183 - K Ubiquitination 21963094 3996 110183 - K Ubiquitination 23000965

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID LLGL1 Homo sapiens (Human) 19; 293; 27 "19,PQREKLKQELFAF; 293,PCKAINKILWRNC; 27,ELFAFNKTVEHGF" 19:21890473; 293:21890473; 27:21890473 LLGL1 Homo sapiens (Human) 19; 293; 27 "19,PQREKLKQELFAF; 293,PCKAINKILWRNC; 27,ELFAFNKTVEHGF" 19:21890473; 293:21890473; 27:21890473