Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 19 14071333 14071334 + Frame_Shift_Ins INS - - G TCGA-OR-A5K5-01A-11D-A29I-10 TCGA-OR-A5K5-10A-01D-A29L-10 g.chr19:14071333_14071334insG c.1688_1689insG c.(1687-1692)ctggtgfs p.V564fs BLCA 19 14065241 14065241 + Silent SNP C C G TCGA-FD-A6TA-01A-12D-A339-08 TCGA-FD-A6TA-10A-21D-A339-08 g.chr19:14065241C>G c.222C>G c.(220-222)ctC>ctG p.L74L BLCA 19 14065247 14065247 + Silent SNP A A C TCGA-GC-A3RC-01A-11D-A22Z-08 TCGA-GC-A3RC-10B-01D-A22Z-08 g.chr19:14065247A>C c.228A>C c.(226-228)gcA>gcC p.A76A BLCA 19 14066749 14066749 + Missense_Mutation SNP A A G TCGA-XF-A9T0-01A-11D-A391-08 TCGA-XF-A9T0-10A-01D-A394-08 g.chr19:14066749A>G c.392A>G c.(391-393)gAc>gGc p.D131G BLCA 19 14066959 14066959 + Silent SNP C C T TCGA-4Z-AA7M-01A-11D-A391-08 TCGA-4Z-AA7M-10A-01D-A394-08 g.chr19:14066959C>T c.498C>T c.(496-498)ctC>ctT p.L166L BLCA 19 14069917 14069918 + Frame_Shift_Ins INS - - C TCGA-ZF-AA4W-01A-12D-A38G-08 TCGA-ZF-AA4W-10A-01D-A38J-08 g.chr19:14069917_14069918insC c.845_846insC c.(844-849)agccccfs p.SP282fs BLCA 19 14070171 14070171 + Missense_Mutation SNP G G C TCGA-ZF-AA53-01A-11D-A391-08 TCGA-ZF-AA53-10A-01D-A394-08 g.chr19:14070171G>C c.1099G>C c.(1099-1101)Gag>Cag p.E367Q BLCA 19 14070852 14070852 + Silent SNP C C T TCGA-DK-A1AA-01A-11D-A13W-08 TCGA-DK-A1AA-10A-01D-A13W-08 g.chr19:14070852C>T c.1497C>T c.(1495-1497)ttC>ttT p.F499F BRCA 19 14069901 14069902 + Frame_Shift_Ins INS - - GG TCGA-AN-A03X-01A-21W-A019-09 TCGA-AN-A03X-10A-01W-A021-09 g.chr19:14069901_14069902insGG c.829_830insGG c.(829-831)cccfs p.P277fs COAD 19 14067175 14067175 + Missense_Mutation SNP G G A TCGA-A6-6780-01A-11D-1835-10 TCGA-A6-6780-10A-01D-1835-10 g.chr19:14067175G>A c.625G>A c.(625-627)Gca>Aca p.A209T COAD 19 14069917 14069918 + Frame_Shift_Ins INS - - C TCGA-AA-3672-01A-01W-0900-09 TCGA-AA-3672-10A-01W-0900-09 g.chr19:14069917_14069918insC c.845_846insC c.(844-849)agccccfs p.SP282fs COAD 19 14070284 14070284 + Silent SNP G G A TCGA-CM-4743-01A-01D-1719-10 TCGA-CM-4743-10A-01D-1719-10 g.chr19:14070284G>A c.1212G>A c.(1210-1212)ccG>ccA p.P404P COADREAD 19 14067175 14067175 + Missense_Mutation SNP G G A TCGA-A6-6780-01A-11D-1835-10 TCGA-A6-6780-10A-01D-1835-10 g.chr19:14067175G>A c.625G>A c.(625-627)Gca>Aca p.A209T COADREAD 19 14069917 14069918 + Frame_Shift_Ins INS - - C TCGA-AA-3672-01A-01W-0900-09 TCGA-AA-3672-10A-01W-0900-09 g.chr19:14069917_14069918insC c.845_846insC c.(844-849)agccccfs p.SP282fs COADREAD 19 14070284 14070284 + Silent SNP G G A TCGA-CM-4743-01A-01D-1719-10 TCGA-CM-4743-10A-01D-1719-10 g.chr19:14070284G>A c.1212G>A c.(1210-1212)ccG>ccA p.P404P DLBC 19 14066772 14066772 + Missense_Mutation SNP T T C TCGA-G8-6324-01A-11D-2210-10 TCGA-G8-6324-10A-01D-2210-10 g.chr19:14066772T>C c.415T>C c.(415-417)Tac>Cac p.Y139H ESCA 19 14066943 14066943 + Missense_Mutation SNP C C T TCGA-VR-A8EO-01A-11D-A36J-09 TCGA-VR-A8EO-10A-01D-A36M-09 g.chr19:14066943C>T c.482C>T c.(481-483)tCg>tTg p.S161L ESCA 19 14070191 14070191 + Frame_Shift_Del DEL C C - TCGA-L5-A8NM-01A-11D-A37C-09 TCGA-L5-A8NM-11A-12D-A37F-09 g.chr19:14070191delC c.1119delC c.(1117-1119)agcfs p.S373fs GBM 19 14065391 14065391 + Missense_Mutation SNP G G A TCGA-19-1790-01B-01D-1353-08 TCGA-19-1790-10B-01D-1353-08 g.chr19:14065391G>A c.284G>A c.(283-285)aGc>aAc p.S95N GBM 19 14071180 14071180 + Silent SNP G G C TCGA-76-6664-01A-11D-1845-08 TCGA-76-6664-10A-01D-1845-08 g.chr19:14071180G>C c.1608G>C c.(1606-1608)ctG>ctC p.L536L GBMLGG 19 14065391 14065391 + Missense_Mutation SNP G G A TCGA-19-1790-01B-01D-1353-08 TCGA-19-1790-10B-01D-1353-08 g.chr19:14065391G>A c.284G>A c.(283-285)aGc>aAc p.S95N GBMLGG 19 14066828 14066828 + Missense_Mutation SNP C C G TCGA-VM-A8CE-01A-11D-A36O-08 TCGA-VM-A8CE-10A-01D-A367-08 g.chr19:14066828C>G c.471C>G c.(469-471)ttC>ttG p.F157L GBMLGG 19 14071180 14071180 + Silent SNP G G C TCGA-76-6664-01A-11D-1845-08 TCGA-76-6664-10A-01D-1845-08 g.chr19:14071180G>C c.1608G>C c.(1606-1608)ctG>ctC p.L536L HNSC 19 14065187 14065187 + Missense_Mutation SNP G G C TCGA-QK-A8Z8-01A-11D-A391-08 TCGA-QK-A8Z8-10A-01D-A394-08 g.chr19:14065187G>C c.168G>C c.(166-168)aaG>aaC p.K56N HNSC 19 14067054 14067054 + Missense_Mutation SNP A A G TCGA-UF-A71D-01A-12D-A34J-08 TCGA-UF-A71D-10B-01D-A34M-08 g.chr19:14067054A>G c.593A>G c.(592-594)gAt>gGt p.D198G HNSC 19 14069867 14069867 + Silent SNP T T C TCGA-CR-7380-01A-11D-2012-08 TCGA-CR-7380-10A-01D-2013-08 g.chr19:14069867T>C c.795T>C c.(793-795)agT>agC p.S265S HNSC 19 14069909 14069909 + Silent SNP G G A TCGA-CV-5439-01A-01D-1683-08 TCGA-CV-5439-11B-01D-1683-08 g.chr19:14069909G>A c.837G>A c.(835-837)gcG>gcA p.A279A HNSC 19 14070284 14070284 + Silent SNP G G A TCGA-CV-7095-01A-21D-2012-08 TCGA-CV-7095-10A-01D-2013-08 g.chr19:14070284G>A c.1212G>A c.(1210-1212)ccG>ccA p.P404P HNSC 19 14070848 14070848 + Missense_Mutation SNP C C T TCGA-D6-6516-01A-11D-1870-08 TCGA-D6-6516-10A-01D-1870-08 g.chr19:14070848C>T c.1493C>T c.(1492-1494)gCc>gTc p.A498V HNSC 19 14070849 14070849 + Silent SNP C C T TCGA-D6-6516-01A-11D-1870-08 TCGA-D6-6516-10A-01D-1870-08 g.chr19:14070849C>T c.1494C>T c.(1492-1494)gcC>gcT p.A498A HNSC 19 14070879 14070879 + Silent SNP C C T TCGA-CQ-6224-01A-11D-1912-08 TCGA-CQ-6224-10A-01D-1912-08 g.chr19:14070879C>T c.1524C>T c.(1522-1524)ctC>ctT p.L508L HNSC 19 14071164 14071164 + Missense_Mutation SNP T T C TCGA-F7-A624-01A-22D-A30E-08 TCGA-F7-A624-10A-01D-A30H-08 g.chr19:14071164T>C c.1592T>C c.(1591-1593)gTc>gCc p.V531A KIPAN 19 14070072 14070072 + Missense_Mutation SNP G G A TCGA-HE-A5NI-01A-11D-A26P-10 TCGA-HE-A5NI-10A-01D-A26P-10 g.chr19:14070072G>A c.1000G>A c.(1000-1002)Gcc>Acc p.A334T KIRP 19 14070072 14070072 + Missense_Mutation SNP G G A TCGA-HE-A5NI-01A-11D-A26P-10 TCGA-HE-A5NI-10A-01D-A26P-10 g.chr19:14070072G>A c.1000G>A c.(1000-1002)Gcc>Acc p.A334T LGG 19 14066828 14066828 + Missense_Mutation SNP C C G TCGA-VM-A8CE-01A-11D-A36O-08 TCGA-VM-A8CE-10A-01D-A367-08 g.chr19:14066828C>G c.471C>G c.(469-471)ttC>ttG p.F157L LIHC 19 14070706 14070706 + Splice_Site SNP A A G TCGA-CC-A3MA-01A-11D-A20W-10 TCGA-CC-A3MA-10A-01D-A20W-10 g.chr19:14070706A>G c.1439A>G c.(1438-1440)gAg>gGg p.E480G LIHC 19 14071164 14071164 + Missense_Mutation SNP T T C TCGA-FV-A2QR-01A-11D-A20W-10 TCGA-FV-A2QR-11A-11D-A20W-10 g.chr19:14071164T>C c.1592T>C c.(1591-1593)gTc>gCc p.V531A LUAD 19 14065430 14065430 + Missense_Mutation SNP A A G TCGA-49-6761-01A-31D-1945-08 TCGA-49-6761-11A-01D-1945-08 g.chr19:14065430A>G c.323A>G c.(322-324)cAt>cGt p.H108R LUAD 19 14070103 14070103 + Missense_Mutation SNP C C A TCGA-55-7726-01A-11D-2167-08 TCGA-55-7726-10A-01D-2167-08 g.chr19:14070103C>A c.1031C>A c.(1030-1032)cCt>cAt p.P344H LUAD 19 14070233 14070233 + Silent SNP C C G TCGA-55-7994-01A-11D-2184-08 TCGA-55-7994-10A-01D-2184-08 g.chr19:14070233C>G c.1161C>G c.(1159-1161)gtC>gtG p.V387V LUSC 19 14065389 14065389 + Silent SNP C C G TCGA-33-4586-01A-01D-1441-08 TCGA-33-4586-11A-01D-1441-08 g.chr19:14065389C>G c.282C>G c.(280-282)acC>acG p.T94T LUSC 19 14069902 14069902 + Missense_Mutation SNP C C T TCGA-18-3412-01A-01D-0983-08 TCGA-18-3412-11A-01D-0983-08 g.chr19:14069902C>T c.830C>T c.(829-831)cCc>cTc p.P277L LUSC 19 14069908 14069908 + Missense_Mutation SNP C C T TCGA-60-2712-01A-01D-1522-08 TCGA-60-2712-11A-01D-1522-08 g.chr19:14069908C>T c.836C>T c.(835-837)gCg>gTg p.A279V LUSC 19 14070631 14070631 + Missense_Mutation SNP A A G TCGA-39-5019-01A-01D-1817-08 TCGA-39-5019-11A-01D-1817-08 g.chr19:14070631A>G c.1364A>G c.(1363-1365)aAt>aGt p.N455S OV 19 14070608 14070608 + Silent SNP A A G TCGA-10-0930-01A-02W-0421-09 TCGA-10-0930-11A-01W-0977-09 g.chr19:14070608A>G c.1341A>G c.(1339-1341)acA>acG p.T447T PAAD 19 14067054 14067054 + Missense_Mutation SNP A A G TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr19:14067054A>G c.593A>G c.(592-594)gAt>gGt p.D198G PAAD 19 14069989 14069989 + Missense_Mutation SNP G G A TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr19:14069989G>A c.917G>A c.(916-918)cGt>cAt p.R306H PAAD 19 14071137 14071137 + Missense_Mutation SNP A A G TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr19:14071137A>G c.1565A>G c.(1564-1566)gAc>gGc p.D522G PRAD 19 14070278 14070278 + Silent SNP G G A TCGA-XK-AAIW-01A-11D-A41K-08 TCGA-XK-AAIW-10A-01D-A41N-08 g.chr19:14070278G>A c.1206G>A c.(1204-1206)acG>acA p.T402T PRAD 19 14070466 14070466 + Missense_Mutation SNP G G A TCGA-EJ-7782-01A-11D-2114-08 TCGA-EJ-7782-10A-01D-2114-08 g.chr19:14070466G>A c.1292G>A c.(1291-1293)cGg>cAg p.R431Q PRAD 19 14070696 14070696 + Missense_Mutation SNP G G A TCGA-XK-AAIW-01A-11D-A41K-08 TCGA-XK-AAIW-10A-01D-A41N-08 g.chr19:14070696G>A c.1429G>A c.(1429-1431)Gtc>Atc p.V477I SKCM 19 14067018 14067018 + Missense_Mutation SNP C C T TCGA-RP-A693-06A-13D-A30X-08 TCGA-RP-A693-10A-01D-A30X-08 g.chr19:14067018C>T c.557C>T c.(556-558)gCc>gTc p.A186V SKCM 19 14069995 14069995 + Missense_Mutation SNP C C T TCGA-RP-A695-06A-11D-A30X-08 TCGA-RP-A695-10A-01D-A30X-08 g.chr19:14069995C>T c.923C>T c.(922-924)tCt>tTt p.S308F SKCM 19 14070065 14070065 + Silent SNP C C T TCGA-DA-A1IA-06A-11D-A196-08 TCGA-DA-A1IA-10A-01D-A198-08 g.chr19:14070065C>T c.993C>T c.(991-993)gcC>gcT p.A331A SKCM 19 14071304 14071304 + Silent SNP G G A TCGA-GN-A266-06A-11D-A197-08 TCGA-GN-A266-10A-01D-A199-08 g.chr19:14071304G>A c.1659G>A c.(1657-1659)aaG>aaA p.K553K

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-US 19 14065247 14065247 single base substitution A C 3_prime_UTR_variant BLCA-US 19 14065247 14065247 single base substitution A C splice_region_variant BLCA-US 19 14065247 14065247 single base substitution A C upstream_gene_variant BLCA-US 19 14070852 14070852 single base substitution C T downstream_gene_variant BLCA-US 19 14070852 14070852 single base substitution C T exon_variant BLCA-US 19 14070852 14070852 single base substitution C T synonymous_variant F499F 1497C>T BLCA-US 19 14070852 14070852 single base substitution C T synonymous_variant F99F 297C>T BLCA-US 19 14076445 14076445 single base substitution G A downstream_gene_variant BRCA-EU 19 14059287 14059287 single base substitution G A upstream_gene_variant BRCA-EU 19 14059525 14059525 single base substitution G C upstream_gene_variant BRCA-EU 19 14060246 14060246 single base substitution G C upstream_gene_variant BRCA-EU 19 14060476 14060476 single base substitution C A upstream_gene_variant BRCA-EU 19 14061178 14061178 single base substitution C T upstream_gene_variant BRCA-EU 19 14061272 14061272 single base substitution G A upstream_gene_variant BRCA-EU 19 14061606 14061606 single base substitution C T upstream_gene_variant BRCA-EU 19 14062122 14062122 deletion of <=200bp A - upstream_gene_variant BRCA-EU 19 14062507 14062507 single base substitution G A upstream_gene_variant BRCA-EU 19 14062538 14062538 single base substitution C T upstream_gene_variant BRCA-EU 19 14062664 14062664 single base substitution C T upstream_gene_variant BRCA-EU 19 14064018 14064018 single base substitution C T 3_prime_UTR_variant BRCA-EU 19 14064018 14064018 single base substitution C T intron_variant BRCA-EU 19 14064018 14064018 single base substitution C T upstream_gene_variant BRCA-EU 19 14064249 14064249 single base substitution G C intron_variant BRCA-EU 19 14064249 14064249 single base substitution G C upstream_gene_variant BRCA-EU 19 14064294 14064294 single base substitution C T intron_variant BRCA-EU 19 14064294 14064294 single base substitution C T upstream_gene_variant BRCA-EU 19 14064522 14064522 single base substitution C T intron_variant BRCA-EU 19 14064522 14064522 single base substitution C T upstream_gene_variant BRCA-EU 19 14065161 14065161 single base substitution C G 3_prime_UTR_variant BRCA-EU 19 14065161 14065161 single base substitution C G missense_variant Q48E 142C>G BRCA-EU 19 14065161 14065161 single base substitution C G upstream_gene_variant BRCA-EU 19 14065691 14065691 single base substitution G T downstream_gene_variant BRCA-EU 19 14065691 14065691 single base substitution G T intron_variant BRCA-EU 19 14065691 14065691 single base substitution G T upstream_gene_variant BRCA-EU 19 14066475 14066475 single base substitution G C downstream_gene_variant BRCA-EU 19 14066475 14066475 single base substitution G C intron_variant BRCA-EU 19 14066475 14066475 single base substitution G C upstream_gene_variant BRCA-EU 19 14067787 14067787 single base substitution C G downstream_gene_variant BRCA-EU 19 14067787 14067787 single base substitution C G intron_variant BRCA-EU 19 14067787 14067787 single base substitution C G upstream_gene_variant BRCA-EU 19 14067975 14067975 single base substitution C T downstream_gene_variant BRCA-EU 19 14067975 14067975 single base substitution C T intron_variant BRCA-EU 19 14067975 14067975 single base substitution C T upstream_gene_variant BRCA-EU 19 14068187 14068187 single base substitution C T downstream_gene_variant BRCA-EU 19 14068187 14068187 single base substitution C T intron_variant BRCA-EU 19 14068187 14068187 single base substitution C T upstream_gene_variant BRCA-EU 19 14068767 14068767 single base substitution G T downstream_gene_variant BRCA-EU 19 14068767 14068767 single base substitution G T intron_variant BRCA-EU 19 14068767 14068767 single base substitution G T upstream_gene_variant BRCA-EU 19 14069221 14069221 single base substitution G A downstream_gene_variant BRCA-EU 19 14069221 14069221 single base substitution G A intron_variant BRCA-EU 19 14069221 14069221 single base substitution G A upstream_gene_variant BRCA-EU 19 14070351 14070351 single base substitution C A intron_variant BRCA-EU 19 14070351 14070351 single base substitution C A upstream_gene_variant BRCA-EU 19 14071402 14071402 single base substitution G A downstream_gene_variant BRCA-EU 19 14071402 14071402 single base substitution G A intron_variant BRCA-EU 19 14072438 14072438 single base substitution T G downstream_gene_variant BRCA-EU 19 14073642 14073642 single base substitution G T downstream_gene_variant BRCA-EU 19 14073708 14073708 single base substitution C T downstream_gene_variant BRCA-EU 19 14074644 14074644 insertion of <=200bp - CCCGC downstream_gene_variant BRCA-EU 19 14076699 14076699 single base substitution C G downstream_gene_variant BRCA-EU 19 14076825 14076825 single base substitution G C downstream_gene_variant BRCA-FR 19 14061606 14061606 single base substitution C T upstream_gene_variant BRCA-FR 19 14062538 14062538 single base substitution C T upstream_gene_variant BRCA-FR 19 14062664 14062664 single base substitution C T upstream_gene_variant BRCA-FR 19 14066475 14066475 single base substitution G C downstream_gene_variant BRCA-FR 19 14066475 14066475 single base substitution G C intron_variant BRCA-FR 19 14066475 14066475 single base substitution G C upstream_gene_variant BRCA-FR 19 14067787 14067787 single base substitution C G downstream_gene_variant BRCA-FR 19 14067787 14067787 single base substitution C G intron_variant BRCA-FR 19 14067787 14067787 single base substitution C G upstream_gene_variant BRCA-FR 19 14067975 14067975 single base substitution C T downstream_gene_variant BRCA-FR 19 14067975 14067975 single base substitution C T intron_variant BRCA-FR 19 14067975 14067975 single base substitution C T upstream_gene_variant BRCA-FR 19 14068187 14068187 single base substitution C T downstream_gene_variant BRCA-FR 19 14068187 14068187 single base substitution C T intron_variant BRCA-FR 19 14068187 14068187 single base substitution C T upstream_gene_variant BRCA-FR 19 14073642 14073642 single base substitution G T downstream_gene_variant BRCA-FR 19 14074669 14074669 single base substitution C T downstream_gene_variant BRCA-UK 19 14062214 14062214 single base substitution G A upstream_gene_variant BRCA-US 19 14069901 14069901 insertion of <=200bp - GG downstream_gene_variant BRCA-US 19 14069901 14069901 insertion of <=200bp - GG frameshift_variant P277G? BRCA-US 19 14069901 14069901 insertion of <=200bp - GG frameshift_variant P53G? BRCA-US 19 14069901 14069901 insertion of <=200bp - GG upstream_gene_variant BRCA-US 19 14073674 14073674 single base substitution C A downstream_gene_variant BRCA-US 19 14074007 14074009 deletion of <=200bp TCG - downstream_gene_variant BRCA-US 19 14074749 14074749 single base substitution G A downstream_gene_variant BRCA-US 19 14076329 14076329 single base substitution C G downstream_gene_variant BRCA-US 19 14076542 14076542 single base substitution A C downstream_gene_variant BTCA-JP 19 14063877 14063877 single base substitution A T exon_variant BTCA-JP 19 14063877 14063877 single base substitution A T intron_variant BTCA-JP 19 14063877 14063877 single base substitution A T upstream_gene_variant BTCA-JP 19 14066802 14066802 single base substitution G A downstream_gene_variant BTCA-JP 19 14066802 14066802 single base substitution G A missense_variant A149T 445G>A BTCA-JP 19 14066802 14066802 single base substitution G A upstream_gene_variant BTCA-JP 19 14074011 14074011 single base substitution C T downstream_gene_variant BTCA-JP 19 14076280 14076280 single base substitution T C downstream_gene_variant CESC-US 19 14073659 14073659 single base substitution C T downstream_gene_variant CESC-US 19 14073987 14073987 single base substitution C T downstream_gene_variant CESC-US 19 14074708 14074708 single base substitution G A downstream_gene_variant CLLE-ES 19 14065196 14065196 single base substitution C T 3_prime_UTR_variant CLLE-ES 19 14065196 14065196 single base substitution C T synonymous_variant P59P 177C>T CLLE-ES 19 14065196 14065196 single base substitution C T upstream_gene_variant CLLE-ES 19 14067063 14067063 single base substitution G A downstream_gene_variant CLLE-ES 19 14067063 14067063 single base substitution G A missense_variant R201Q 602G>A CLLE-ES 19 14067063 14067063 single base substitution G A upstream_gene_variant CLLE-ES 19 14069428 14069428 single base substitution G A downstream_gene_variant CLLE-ES 19 14069428 14069428 single base substitution G A intron_variant CLLE-ES 19 14069428 14069428 single base substitution G A upstream_gene_variant COAD-US 19 14067013 14067013 single base substitution C T downstream_gene_variant COAD-US 19 14067013 14067013 single base substitution C T synonymous_variant T184T 552C>T COAD-US 19 14067013 14067013 single base substitution C T upstream_gene_variant COAD-US 19 14070176 14070176 single base substitution G A downstream_gene_variant COAD-US 19 14070176 14070176 single base substitution G A synonymous_variant T144T 432G>A COAD-US 19 14070176 14070176 single base substitution G A synonymous_variant T368T 1104G>A COAD-US 19 14070176 14070176 single base substitution G A upstream_gene_variant COAD-US 19 14070284 14070284 single base substitution G A synonymous_variant P180P 540G>A COAD-US 19 14070284 14070284 single base substitution G A synonymous_variant P404P 1212G>A COAD-US 19 14070284 14070284 single base substitution G A upstream_gene_variant COAD-US 19 14076470 14076470 single base substitution A G downstream_gene_variant COCA-CN 19 14065408 14065408 single base substitution G A downstream_gene_variant COCA-CN 19 14065408 14065408 single base substitution G A missense_variant D101N 301G>A COCA-CN 19 14065408 14065408 single base substitution G A upstream_gene_variant COCA-CN 19 14066737 14066737 single base substitution G T downstream_gene_variant COCA-CN 19 14066737 14066737 single base substitution G T missense_variant R127L 380G>T COCA-CN 19 14066737 14066737 single base substitution G T upstream_gene_variant COCA-CN 19 14067250 14067250 single base substitution G A downstream_gene_variant COCA-CN 19 14067250 14067250 single base substitution G A missense_variant A10T 28G>A COCA-CN 19 14067250 14067250 single base substitution G A missense_variant A234T 700G>A COCA-CN 19 14067250 14067250 single base substitution G A upstream_gene_variant COCA-CN 19 14074651 14074651 single base substitution C T downstream_gene_variant COCA-CN 19 14074797 14074797 single base substitution G A downstream_gene_variant COCA-CN 19 14074805 14074805 single base substitution G A downstream_gene_variant ESAD-UK 19 14058949 14058949 single base substitution A C upstream_gene_variant ESAD-UK 19 14058951 14058951 single base substitution A T upstream_gene_variant ESAD-UK 19 14059823 14059823 single base substitution G A upstream_gene_variant ESAD-UK 19 14060434 14060434 insertion of <=200bp - T upstream_gene_variant ESAD-UK 19 14064928 14064928 single base substitution G A intron_variant ESAD-UK 19 14064928 14064928 single base substitution G A upstream_gene_variant ESAD-UK 19 14066366 14066366 single base substitution G T downstream_gene_variant ESAD-UK 19 14066366 14066366 single base substitution G T intron_variant ESAD-UK 19 14066366 14066366 single base substitution G T upstream_gene_variant ESAD-UK 19 14069983 14069983 single base substitution C T downstream_gene_variant ESAD-UK 19 14069983 14069983 single base substitution C T missense_variant P304L 911C>T ESAD-UK 19 14069983 14069983 single base substitution C T missense_variant P80L 239C>T ESAD-UK 19 14069983 14069983 single base substitution C T upstream_gene_variant ESAD-UK 19 14070138 14070138 single base substitution C T downstream_gene_variant ESAD-UK 19 14070138 14070138 single base substitution C T missense_variant R132C 394C>T ESAD-UK 19 14070138 14070138 single base substitution C T missense_variant R356C 1066C>T ESAD-UK 19 14070138 14070138 single base substitution C T upstream_gene_variant ESAD-UK 19 14073606 14073606 single base substitution G A downstream_gene_variant ESAD-UK 19 14073774 14073774 single base substitution C T downstream_gene_variant ESAD-UK 19 14074171 14074171 single base substitution C T downstream_gene_variant ESAD-UK 19 14075783 14075783 single base substitution C T downstream_gene_variant GBM-US 19 14065391 14065391 single base substitution G A downstream_gene_variant GBM-US 19 14065391 14065391 single base substitution G A missense_variant S95N 284G>A GBM-US 19 14065391 14065391 single base substitution G A upstream_gene_variant GBM-US 19 14071180 14071180 single base substitution G C downstream_gene_variant GBM-US 19 14071180 14071180 single base substitution G C exon_variant GBM-US 19 14071180 14071180 single base substitution G C synonymous_variant L136L 408G>C GBM-US 19 14071180 14071180 single base substitution G C synonymous_variant L536L 1608G>C KIRP-US 19 14070072 14070072 single base substitution G A downstream_gene_variant KIRP-US 19 14070072 14070072 single base substitution G A missense_variant A110T 328G>A KIRP-US 19 14070072 14070072 single base substitution G A missense_variant A334T 1000G>A KIRP-US 19 14070072 14070072 single base substitution G A upstream_gene_variant LAML-KR 19 14065341 14065341 single base substitution T C downstream_gene_variant LAML-KR 19 14065341 14065341 single base substitution T C synonymous_variant H78H 234T>C LAML-KR 19 14065341 14065341 single base substitution T C upstream_gene_variant LICA-CN 19 14070586 14070586 single base substitution A C exon_variant LICA-CN 19 14070586 14070586 single base substitution A C missense_variant Y247S 740A>C LICA-CN 19 14070586 14070586 single base substitution A C missense_variant Y40S 119A>C LICA-CN 19 14070586 14070586 single base substitution A C missense_variant Y440S 1319A>C LICA-CN 19 14070586 14070586 single base substitution A C upstream_gene_variant LICA-CN 19 14071389 14071389 single base substitution A G downstream_gene_variant LICA-CN 19 14071389 14071389 single base substitution A G exon_variant LICA-CN 19 14071389 14071389 single base substitution A G missense_variant K182E 544A>G LICA-CN 19 14071389 14071389 single base substitution A G missense_variant K582E 1744A>G LICA-FR 19 14059766 14059766 single base substitution A G upstream_gene_variant LICA-FR 19 14076490 14076490 single base substitution C A downstream_gene_variant LIRI-JP 19 14058944 14058944 single base substitution C T upstream_gene_variant LIRI-JP 19 14062766 14062766 single base substitution C G upstream_gene_variant LIRI-JP 19 14066902 14066902 single base substitution C T downstream_gene_variant LIRI-JP 19 14066902 14066902 single base substitution C T intron_variant LIRI-JP 19 14066902 14066902 single base substitution C T upstream_gene_variant LIRI-JP 19 14067866 14067866 single base substitution C T downstream_gene_variant LIRI-JP 19 14067866 14067866 single base substitution C T intron_variant LIRI-JP 19 14067866 14067866 single base substitution C T upstream_gene_variant LIRI-JP 19 14069261 14069262 deletion of <=200bp TG - downstream_gene_variant LIRI-JP 19 14069261 14069262 deletion of <=200bp TG - intron_variant LIRI-JP 19 14069261 14069262 deletion of <=200bp TG - upstream_gene_variant LIRI-JP 19 14069650 14069650 single base substitution G A downstream_gene_variant LIRI-JP 19 14069650 14069650 single base substitution G A intron_variant LIRI-JP 19 14069650 14069650 single base substitution G A upstream_gene_variant LUSC-KR 19 14063344 14063344 single base substitution C A exon_variant LUSC-KR 19 14063344 14063344 single base substitution C A stop_gained S7* 20C>A LUSC-KR 19 14063344 14063344 single base substitution C A upstream_gene_variant LUSC-KR 19 14063792 14063792 single base substitution C A intron_variant LUSC-KR 19 14063792 14063792 single base substitution C A upstream_gene_variant LUSC-KR 19 14074676 14074676 single base substitution G A downstream_gene_variant LUSC-US 19 14065389 14065389 single base substitution C G downstream_gene_variant LUSC-US 19 14065389 14065389 single base substitution C G synonymous_variant T94T 282C>G LUSC-US 19 14065389 14065389 single base substitution C G upstream_gene_variant LUSC-US 19 14069902 14069902 single base substitution C T downstream_gene_variant LUSC-US 19 14069902 14069902 single base substitution C T missense_variant P277L 830C>T LUSC-US 19 14069902 14069902 single base substitution C T missense_variant P53L 158C>T LUSC-US 19 14069902 14069902 single base substitution C T upstream_gene_variant LUSC-US 19 14069908 14069908 single base substitution C T downstream_gene_variant LUSC-US 19 14069908 14069908 single base substitution C T missense_variant A279V 836C>T LUSC-US 19 14069908 14069908 single base substitution C T missense_variant A55V 164C>T LUSC-US 19 14069908 14069908 single base substitution C T upstream_gene_variant LUSC-US 19 14070631 14070631 single base substitution A G exon_variant LUSC-US 19 14070631 14070631 single base substitution A G missense_variant N262S 785A>G LUSC-US 19 14070631 14070631 single base substitution A G missense_variant N455S 1364A>G LUSC-US 19 14070631 14070631 single base substitution A G missense_variant N55S 164A>G LUSC-US 19 14070631 14070631 single base substitution A G upstream_gene_variant MALY-DE 19 14064417 14064417 single base substitution G C intron_variant MALY-DE 19 14064417 14064417 single base substitution G C upstream_gene_variant MALY-DE 19 14076117 14076117 single base substitution C T downstream_gene_variant MELA-AU 19 14058617 14058617 single base substitution G A upstream_gene_variant MELA-AU 19 14058890 14058890 single base substitution G A upstream_gene_variant MELA-AU 19 14058982 14058982 single base substitution G A upstream_gene_variant MELA-AU 19 14059097 14059097 single base substitution C T upstream_gene_variant MELA-AU 19 14059455 14059455 single base substitution C T upstream_gene_variant MELA-AU 19 14059735 14059735 insertion of <=200bp - A upstream_gene_variant MELA-AU 19 14060241 14060241 single base substitution C T upstream_gene_variant MELA-AU 19 14061207 14061207 single base substitution C T upstream_gene_variant MELA-AU 19 14061220 14061220 single base substitution G A upstream_gene_variant MELA-AU 19 14061395 14061396 multiple base substitution (>=2bp and <=200bp) CC TT upstream_gene_variant MELA-AU 19 14061771 14061771 single base substitution C T upstream_gene_variant MELA-AU 19 14061779 14061779 single base substitution T G upstream_gene_variant MELA-AU 19 14061889 14061889 single base substitution T G upstream_gene_variant MELA-AU 19 14061963 14061963 single base substitution A G upstream_gene_variant MELA-AU 19 14062039 14062039 single base substitution C T upstream_gene_variant MELA-AU 19 14062172 14062172 single base substitution G A upstream_gene_variant MELA-AU 19 14062351 14062351 single base substitution T C upstream_gene_variant MELA-AU 19 14062382 14062382 single base substitution C T upstream_gene_variant MELA-AU 19 14063001 14063001 single base substitution G A upstream_gene_variant MELA-AU 19 14063006 14063006 single base substitution C T upstream_gene_variant MELA-AU 19 14063210 14063210 single base substitution G A upstream_gene_variant MELA-AU 19 14063225 14063225 single base substitution C T upstream_gene_variant MELA-AU 19 14063275 14063275 single base substitution G A upstream_gene_variant MELA-AU 19 14063276 14063276 single base substitution G A upstream_gene_variant MELA-AU 19 14063282 14063282 single base substitution G A upstream_gene_variant MELA-AU 19 14064627 14064627 single base substitution T A intron_variant MELA-AU 19 14064627 14064627 single base substitution T A upstream_gene_variant MELA-AU 19 14064858 14064858 single base substitution C T intron_variant MELA-AU 19 14064858 14064858 single base substitution C T upstream_gene_variant MELA-AU 19 14065901 14065901 single base substitution G A downstream_gene_variant MELA-AU 19 14065901 14065901 single base substitution G A intron_variant MELA-AU 19 14065901 14065901 single base substitution G A upstream_gene_variant MELA-AU 19 14066858 14066858 single base substitution G A downstream_gene_variant MELA-AU 19 14066858 14066858 single base substitution G A intron_variant MELA-AU 19 14066858 14066858 single base substitution G A upstream_gene_variant MELA-AU 19 14068991 14068991 single base substitution C T downstream_gene_variant MELA-AU 19 14068991 14068991 single base substitution C T intron_variant MELA-AU 19 14068991 14068991 single base substitution C T upstream_gene_variant MELA-AU 19 14071230 14071230 single base substitution A G downstream_gene_variant MELA-AU 19 14071230 14071230 single base substitution A G exon_variant MELA-AU 19 14071230 14071230 single base substitution A G intron_variant MELA-AU 19 14071460 14071460 single base substitution C T downstream_gene_variant MELA-AU 19 14071460 14071460 single base substitution C T intron_variant MELA-AU 19 14072508 14072508 single base substitution G A downstream_gene_variant MELA-AU 19 14073940 14073940 single base substitution C T downstream_gene_variant MELA-AU 19 14074404 14074404 single base substitution C T downstream_gene_variant MELA-AU 19 14074855 14074855 single base substitution G A downstream_gene_variant MELA-AU 19 14075468 14075468 single base substitution A T downstream_gene_variant MELA-AU 19 14076956 14076956 single base substitution G A downstream_gene_variant ORCA-IN 19 14061997 14061997 single base substitution C T upstream_gene_variant ORCA-IN 19 14066730 14066730 single base substitution C A downstream_gene_variant ORCA-IN 19 14066730 14066730 single base substitution C A missense_variant Q125K 373C>A ORCA-IN 19 14066730 14066730 single base substitution C A upstream_gene_variant ORCA-IN 19 14069908 14069908 single base substitution C T downstream_gene_variant ORCA-IN 19 14069908 14069908 single base substitution C T missense_variant A279V 836C>T ORCA-IN 19 14069908 14069908 single base substitution C T missense_variant A55V 164C>T ORCA-IN 19 14069908 14069908 single base substitution C T upstream_gene_variant ORCA-IN 19 14075213 14075214 deletion of <=200bp TA - downstream_gene_variant OV-AU 19 14061194 14061194 single base substitution C A upstream_gene_variant OV-AU 19 14061487 14061487 single base substitution T G upstream_gene_variant OV-AU 19 14064374 14064374 single base substitution C G intron_variant OV-AU 19 14064374 14064374 single base substitution C G upstream_gene_variant OV-AU 19 14074562 14074562 single base substitution G C downstream_gene_variant OV-US 19 14070608 14070608 single base substitution A G exon_variant OV-US 19 14070608 14070608 single base substitution A G synonymous_variant T254T 762A>G OV-US 19 14070608 14070608 single base substitution A G synonymous_variant T447T 1341A>G OV-US 19 14070608 14070608 single base substitution A G synonymous_variant T47T 141A>G OV-US 19 14070608 14070608 single base substitution A G upstream_gene_variant PACA-AU 19 14060498 14060498 insertion of <=200bp - T upstream_gene_variant PACA-AU 19 14071351 14071351 single base substitution G T downstream_gene_variant PACA-AU 19 14071351 14071351 single base substitution G T exon_variant PACA-AU 19 14071351 14071351 single base substitution G T missense_variant G169V 506G>T PACA-AU 19 14071351 14071351 single base substitution G T missense_variant G569V 1706G>T PACA-AU 19 14074813 14074813 single base substitution C T downstream_gene_variant PACA-AU 19 14075628 14075628 single base substitution G C downstream_gene_variant PACA-CA 19 14059939 14059939 deletion of <=200bp T - upstream_gene_variant PACA-CA 19 14063256 14063256 single base substitution A G upstream_gene_variant PACA-CA 19 14067112 14067112 deletion of <=200bp C - downstream_gene_variant PACA-CA 19 14067112 14067112 deletion of <=200bp C - intron_variant PACA-CA 19 14067112 14067112 deletion of <=200bp C - upstream_gene_variant PACA-CA 19 14072119 14072119 single base substitution C G 3_prime_UTR_variant PACA-CA 19 14072119 14072119 single base substitution C G downstream_gene_variant PACA-CA 19 14072119 14072119 single base substitution C G exon_variant PACA-CA 19 14076281 14076281 single base substitution C T downstream_gene_variant PACA-CA 19 14076405 14076405 single base substitution G A downstream_gene_variant PAEN-AU 19 14071406 14071406 single base substitution A C downstream_gene_variant PAEN-AU 19 14071406 14071406 single base substitution A C intron_variant PAEN-AU 19 14073777 14073777 single base substitution C T downstream_gene_variant PAEN-IT 19 14071646 14071646 single base substitution C G downstream_gene_variant PAEN-IT 19 14071646 14071646 single base substitution C G intron_variant PRAD-CA 19 14059597 14059597 single base substitution A T upstream_gene_variant PRAD-CA 19 14062095 14062095 single base substitution A C upstream_gene_variant PRAD-CA 19 14064615 14064615 single base substitution G C intron_variant PRAD-CA 19 14064615 14064615 single base substitution G C upstream_gene_variant PRAD-UK 19 14059385 14059385 single base substitution C T upstream_gene_variant PRAD-UK 19 14069157 14069157 single base substitution G A downstream_gene_variant PRAD-UK 19 14069157 14069157 single base substitution G A intron_variant PRAD-UK 19 14069157 14069157 single base substitution G A upstream_gene_variant PRAD-US 19 14070466 14070466 single base substitution G A exon_variant PRAD-US 19 14070466 14070466 single base substitution G A missense_variant R207Q 620G>A PRAD-US 19 14070466 14070466 single base substitution G A missense_variant R31Q 92G>A PRAD-US 19 14070466 14070466 single base substitution G A missense_variant R431Q 1292G>A PRAD-US 19 14070466 14070466 single base substitution G A upstream_gene_variant READ-US 19 14063376 14063376 single base substitution G A exon_variant READ-US 19 14063376 14063376 single base substitution G A missense_variant G18S 52G>A READ-US 19 14063376 14063376 single base substitution G A upstream_gene_variant READ-US 19 14070805 14070805 single base substitution G T downstream_gene_variant READ-US 19 14070805 14070805 single base substitution G T exon_variant READ-US 19 14070805 14070805 single base substitution G T stop_gained E484* 1450G>T READ-US 19 14070805 14070805 single base substitution G T stop_gained E84* 250G>T RECA-EU 19 14059688 14059688 single base substitution G A upstream_gene_variant RECA-EU 19 14067595 14067595 single base substitution T C downstream_gene_variant RECA-EU 19 14067595 14067595 single base substitution T C intron_variant RECA-EU 19 14067595 14067595 single base substitution T C upstream_gene_variant SKCA-BR 19 14059179 14059180 deletion of <=200bp AT - upstream_gene_variant SKCA-BR 19 14059267 14059267 single base substitution A C upstream_gene_variant SKCA-BR 19 14059772 14059772 single base substitution C T upstream_gene_variant SKCA-BR 19 14060897 14060897 single base substitution G A upstream_gene_variant SKCA-BR 19 14061028 14061028 single base substitution G A upstream_gene_variant SKCA-BR 19 14063697 14063697 single base substitution T G intron_variant SKCA-BR 19 14063697 14063697 single base substitution T G upstream_gene_variant SKCA-BR 19 14063703 14063703 single base substitution C G intron_variant SKCA-BR 19 14063703 14063703 single base substitution C G upstream_gene_variant SKCA-BR 19 14064923 14064923 single base substitution A C intron_variant SKCA-BR 19 14064923 14064923 single base substitution A C upstream_gene_variant SKCA-BR 19 14070915 14070916 deletion of <=200bp AG - downstream_gene_variant SKCA-BR 19 14070915 14070916 deletion of <=200bp AG - exon_variant SKCA-BR 19 14070915 14070916 deletion of <=200bp AG - intron_variant SKCA-BR 19 14070922 14070922 single base substitution C T downstream_gene_variant SKCA-BR 19 14070922 14070922 single base substitution C T exon_variant SKCA-BR 19 14070922 14070922 single base substitution C T intron_variant SKCA-BR 19 14072813 14072813 single base substitution T G downstream_gene_variant SKCA-BR 19 14074148 14074148 single base substitution T C downstream_gene_variant SKCA-BR 19 14076943 14076943 single base substitution A G downstream_gene_variant SKCA-BR 19 14077001 14077001 single base substitution A C downstream_gene_variant SKCM-US 19 14067018 14067018 single base substitution C T downstream_gene_variant SKCM-US 19 14067018 14067018 single base substitution C T missense_variant A186V 557C>T SKCM-US 19 14067018 14067018 single base substitution C T upstream_gene_variant SKCM-US 19 14069995 14069995 single base substitution C T downstream_gene_variant SKCM-US 19 14069995 14069995 single base substitution C T missense_variant S308F 923C>T SKCM-US 19 14069995 14069995 single base substitution C T missense_variant S84F 251C>T SKCM-US 19 14069995 14069995 single base substitution C T upstream_gene_variant SKCM-US 19 14070065 14070065 single base substitution C T downstream_gene_variant SKCM-US 19 14070065 14070065 single base substitution C T synonymous_variant A107A 321C>T SKCM-US 19 14070065 14070065 single base substitution C T synonymous_variant A331A 993C>T SKCM-US 19 14070065 14070065 single base substitution C T upstream_gene_variant SKCM-US 19 14071304 14071304 single base substitution G A downstream_gene_variant SKCM-US 19 14071304 14071304 single base substitution G A exon_variant SKCM-US 19 14071304 14071304 single base substitution G A synonymous_variant K153K 459G>A SKCM-US 19 14071304 14071304 single base substitution G A synonymous_variant K553K 1659G>A SKCM-US 19 14074027 14074027 single base substitution G A downstream_gene_variant STAD-US 19 14067019 14067019 single base substitution C T downstream_gene_variant STAD-US 19 14067019 14067019 single base substitution C T synonymous_variant A186A 558C>T STAD-US 19 14067019 14067019 single base substitution C T upstream_gene_variant STAD-US 19 14067214 14067214 single base substitution T C downstream_gene_variant STAD-US 19 14067214 14067214 single base substitution T C missense_variant Y222H 664T>C STAD-US 19 14067214 14067214 single base substitution T C upstream_gene_variant STAD-US 19 14069937 14069937 single base substitution C T downstream_gene_variant STAD-US 19 14069937 14069937 single base substitution C T missense_variant P289S 865C>T STAD-US 19 14069937 14069937 single base substitution C T missense_variant P65S 193C>T STAD-US 19 14069937 14069937 single base substitution C T upstream_gene_variant STAD-US 19 14070014 14070014 single base substitution G A downstream_gene_variant STAD-US 19 14070014 14070014 single base substitution G A synonymous_variant S314S 942G>A STAD-US 19 14070014 14070014 single base substitution G A synonymous_variant S90S 270G>A STAD-US 19 14070014 14070014 single base substitution G A upstream_gene_variant STAD-US 19 14074062 14074062 single base substitution G A downstream_gene_variant THCA-SA 19 14072734 14072734 single base substitution G A downstream_gene_variant THCA-SA 19 14074441 14074441 single base substitution C T downstream_gene_variant UCEC-US 19 14065241 14065241 single base substitution C A 3_prime_UTR_variant UCEC-US 19 14065241 14065241 single base substitution C A synonymous_variant L74L 222C>A UCEC-US 19 14065241 14065241 single base substitution C A upstream_gene_variant UCEC-US 19 14065247 14065247 single base substitution A G 3_prime_UTR_variant UCEC-US 19 14065247 14065247 single base substitution A G splice_region_variant UCEC-US 19 14065247 14065247 single base substitution A G upstream_gene_variant UCEC-US 19 14067218 14067218 single base substitution A T downstream_gene_variant UCEC-US 19 14067218 14067218 single base substitution A T missense_variant Q223L 668A>T UCEC-US 19 14067218 14067218 single base substitution A T upstream_gene_variant UCEC-US 19 14071290 14071290 single base substitution A G downstream_gene_variant UCEC-US 19 14071290 14071290 single base substitution A G exon_variant UCEC-US 19 14071290 14071290 single base substitution A G missense_variant S149G 445A>G UCEC-US 19 14071290 14071290 single base substitution A G missense_variant S549G 1645A>G UCEC-US 19 14074059 14074059 single base substitution G A downstream_gene_variant UCEC-US 19 14074787 14074787 single base substitution C T downstream_gene_variant UCEC-US 19 14076300 14076300 single base substitution G A downstream_gene_variant UCEC-US 19 14076450 14076450 single base substitution G A downstream_gene_variant UCEC-US 19 14076525 14076525 single base substitution C T downstream_gene_variant UCEC-US 19 14076532 14076532 single base substitution G A downstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand TCGA-10-0930-01 COSM118748 c.1341A>G p.T447T Substitution - coding silent 19:13959796-13959796 + sysucc-880T COSM5462804 c.700G>A p.A234T Substitution - Missense 19:13956438-13956438 + 082T COSM1730898 c.565C>T p.P189S Substitution - Missense 19:13956214-13956214 + OSCC-GB_00980111 COSM4882167 c.373C>A p.Q125K Substitution - Missense 19:13955918-13955918 + TCGA-D1-A103-01 COSM991779 c.1645A>G p.S549G Substitution - Missense 19:13960478-13960478 + TCGA-DA-A1IA-06 COSM3529276 c.993C>T p.A331A Substitution - coding silent 19:13959253-13959253 + CN-AML-CR-16-Dx COSM5427986 c.234T>C p.H78H Substitution - coding silent 19:13954529-13954529 + ESO-887 COSM1249733 c.799T>C p.C267R Substitution - Missense 19:13959059-13959059 + 61 COSM5741463 c.574C>T p.R192C Substitution - Missense 19:13956223-13956223 + H358 COSM1194108 c.724G>C p.V242L Substitution - Missense 19:13956462-13956462 + Case1d COSM1717093 c.639G>A p.R213R Substitution - coding silent 19:13956377-13956377 + TARGET-30-PANWRR COSM1284417 c.1525C>T p.R509* Substitution - Nonsense 19:13960068-13960068 + SJBALL263_D COSM3281433 c.762C>T p.C254C Substitution - coding silent 19:13956500-13956500 + TCGA-A6-5661-01 COSM5088928 c.973G>A p.A325T Substitution - Missense 19:13959233-13959233 + NCI-H747 COSM4647073 c.1714G>A p.V572I Substitution - Missense 19:13960547-13960547 + MedB-1 COSM5620624 c.1486C>T p.L496F Substitution - Missense 19:13960029-13960029 + PT52 COSM5940845 c.701C>T p.A234V Substitution - Missense 19:13956439-13956439 + QC2-39-T2 COSM5655848 c.1467C>T p.L489L Substitution - coding silent 19:13960010-13960010 + TCGA-DK-A1AA-01 COSM1304079 c.1497C>T p.F499F Substitution - coding silent 19:13960040-13960040 + ESO-135 COSM1249732 c.262C>T p.R88C Substitution - Missense 19:13954557-13954557 + TCGA-NH-A5IV-01 COSM5183085 c.1526+8C>T p.? Unknown 19:13960077-13960077 + TCGA-CD-A487-01 COSM4074731 c.865C>T p.P289S Substitution - Missense 19:13959125-13959125 + Br27P COSM40830 c.1771G>A p.D591N Substitution - Missense 19:13960963-13960963 + LS411 COSM3281413 c.290G>A p.S97N Substitution - Missense 19:13954585-13954585 + I2L-P23-Tumor-Organoid COSM5365286 c.1780C>T p.R594* Substitution - Nonsense 19:13960972-13960972 + 8035633 COSM3388632 c.1706G>T p.G569V Substitution - Missense 19:13960539-13960539 + TCGA-AD-6895-01 COSM3692407 c.552C>T p.T184T Substitution - coding silent 19:13956201-13956201 + BD104T COSM3281423 c.445G>A p.A149T Substitution - Missense 19:13955990-13955990 + IPMN21 COSM248840 c.1517G>A p.G506D Substitution - Missense 19:13960060-13960060 + CSCC-42-T COSM4519369 c.1006G>A p.G336S Substitution - Missense 19:13959266-13959266 + Hs-578-T COSM1680730 c.1273C>T p.R425C Substitution - Missense 19:13959635-13959635 + GCT28 COSM4278473 c.1438G>A p.E480K Substitution - Missense 19:13959893-13959893 + TCGA-76-6664-01 COSM3403825 c.1608G>C p.L536L Substitution - coding silent 19:13960368-13960368 + HCC007T COSM5809004 c.1319A>C p.Y440S Substitution - Missense 19:13959774-13959774 + TCGA-BR-8360-01 COSM4074729 c.558C>T p.A186A Substitution - coding silent 19:13956207-13956207 + TCGA-CK-4951-01 COSM5149972 c.100G>A p.E34K Substitution - Missense 19:13952612-13952612 + LIM1899 COSM4640188 c.1699A>G p.S567G Substitution - Missense 19:13960532-13960532 + PT44 COSM5927011 c.388C>T p.Q130* Substitution - Nonsense 19:13955933-13955933 + Pat_30_A COSM5854788 c.694C>T p.Q232* Substitution - Nonsense 19:13956432-13956432 + TCGA-33-4586-01 COSM709822 c.282C>G p.T94T Substitution - coding silent 19:13954577-13954577 + 134-08-01TD COSM5419303 c.177C>T p.P59P Substitution - coding silent 19:13954384-13954384 + TCGA-WS-AB45-01 COSM5190440 c.1640T>A p.V547D Substitution - Missense 19:13960473-13960473 + CSCC-54-T COSM4458352 c.1082C>T p.P361L Substitution - Missense 19:13959342-13959342 + OSCC-GB_01160111 COSM709820 c.836C>T p.A279V Substitution - Missense 19:13959096-13959096 + TCGA-CM-4743-01 COSM1390883 c.1212G>A p.P404P Substitution - coding silent 19:13959472-13959472 + TCGA-F5-6814-01 COSM3422455 c.1450G>T p.E484* Substitution - Nonsense 19:13959993-13959993 + 443 COSM4434761 c.1297C>T p.R433W Substitution - Missense 19:13959659-13959659 + T3090 COSM4074732 c.942G>A p.S314S Substitution - coding silent 19:13959202-13959202 + Pat_59_A COSM5854789 c.988C>T p.R330W Substitution - Missense 19:13959248-13959248 + PT45 COSM5927844 c.818A>G p.H273R Substitution - Missense 19:13959078-13959078 + OST204PT COSM1732306 c.1157A>T p.Y386F Substitution - Missense 19:13959417-13959417 + CSCC-56-T COSM4516171 c.1649_1650CC>TT p.S550F Substitution - Missense 19:13960482-13960483 + S02248 COSM5679554 c.1422T>C p.Y474Y Substitution - coding silent 19:13959877-13959877 + TCGA-GC-A3RC-01 COSM3796701 c.228A>C p.A76A Substitution - coding silent 19:13954435-13954435 + T3091 COSM4676356 c.1219+1G>A p.? Unknown 19:13959480-13959480 + PTC-54C COSM4131265 c.1691T>G p.V564G Substitution - Missense 19:13960524-13960524 + TCGA-CK-4951-01 COSM5149973 c.1196G>A p.G399E Substitution - Missense 19:13959456-13959456 + TCGA-AA-3672-01 COSM292739 c.845_846insC p.E285fs*1 Insertion - Frameshift 19:13959105-13959106 + TCGA-RP-A695-06 COSM4897139 c.923C>T p.S308F Substitution - Missense 19:13959183-13959183 + TCGA-18-3412-01 COSM709821 c.830C>T p.P277L Substitution - Missense 19:13959090-13959090 + CSCC-30-T COSM4490828 c.369C>T p.V123V Substitution - coding silent 19:13955914-13955914 + HCC066T COSM5821294 c.1744A>G p.K582E Substitution - Missense 19:13960577-13960577 + TCGA-AN-A03X-01 COSM5833639 c.829_830insGG p.P277fs*87 Insertion - Frameshift 19:13959089-13959090 + T3182 COSM4676352 c.232C>A p.H78N Substitution - Missense 19:13954527-13954527 + 587278 COSM1203060 c.722A>G p.Q241R Substitution - Missense 19:13956460-13956460 + I2L-P23-Tumor-Biopsy COSM5365286 c.1780C>T p.R594* Substitution - Nonsense 19:13960972-13960972 + TCGA-AP-A0LM-01 COSM991776 c.222C>A p.L74L Substitution - coding silent 19:13954429-13954429 + CSCC-29-T COSM4507596 c.750C>T p.S250S Substitution - coding silent 19:13956488-13956488 + sysucc-1397T COSM5474073 c.380G>T p.R127L Substitution - Missense 19:13955925-13955925 + TCGA-B5-A121-01 COSM991778 c.668A>T p.Q223L Substitution - Missense 19:13956406-13956406 + 2492730 COSM5728284 c.987C>T p.R329R Substitution - coding silent 19:13959247-13959247 + TCGA-19-1790-01 COSM3403824 c.284G>A p.S95N Substitution - Missense 19:13954579-13954579 + SA106 COSM214481 c.196_198delAAG p.K66delK Deletion - In frame 19:13954403-13954405 + TCGA-EJ-7782-01 COSM3783187 c.1292G>A p.R431Q Substitution - Missense 19:13959654-13959654 + TCGA-RP-A693-06 COSM4895519 c.557C>T p.A186V Substitution - Missense 19:13956206-13956206 + Pat_06_A COSM5854790 c.1678A>G p.M560V Substitution - Missense 19:13960511-13960511 + 37M COSM5583422 c.1755C>T p.S585S Substitution - coding silent 19:13960947-13960947 + CSCC-27-T COSM4491394 c.379C>T p.R127W Substitution - Missense 19:13955924-13955924 + PD11393a COSM5794256 c.1747+10G>A p.? Unknown 19:13960590-13960590 + TCGA-GN-A266-06 COSM3529277 c.1659G>A p.K553K Substitution - coding silent 19:13960492-13960492 + GCT27 COSM5749605 c.1394G>C p.G465A Substitution - Missense 19:13959849-13959849 + CSCC-10-T COSM4469949 c.162C>T p.F54F Substitution - coding silent 19:13954369-13954369 + PD11753a COSM5776567 c.142C>G p.Q48E Substitution - Missense 19:13954349-13954349 + TCGA-39-5019-01 COSM709819 c.1364A>G p.N455S Substitution - Missense 19:13959819-13959819 + CSCC-55-T COSM4517553 c.369_370CC>TT p.R124W Substitution - Missense 19:13955914-13955915 + T3056 COSM4676355 c.699C>T p.P233P Substitution - coding silent 19:13956437-13956437 + GCT28 COSM3281452 c.1439A>G p.E480G Substitution - Missense 19:13959894-13959894 + TCGA-CK-5916-01 COSM1243196 c.1104G>A p.T368T Substitution - coding silent 19:13959364-13959364 + CSCC-38-T COSM4469060 c.157C>T p.L53F Substitution - Missense 19:13954364-13954364 + LUAD-S01345 COSM396999 c.1018G>A p.E340K Substitution - Missense 19:13959278-13959278 + TCGA-BR-6452-01 COSM4074730 c.664T>C p.Y222H Substitution - Missense 19:13956402-13956402 + TCGA-D1-A17M-01 COSM991777 c.228A>G p.A76A Substitution - coding silent 19:13954435-13954435 + T3118 COSM4676353 c.379C>A p.R127R Substitution - coding silent 19:13955924-13955924 + TCGA-HE-A5NI-01 COSM4414176 c.1000G>A p.A334T Substitution - Missense 19:13959260-13959260 + ESO-081 COSM1243196 c.1104G>A p.T368T Substitution - coding silent 19:13959364-13959364 + YUKAT COSM3281453 c.1440G>A p.E480E Substitution - coding silent 19:13959895-13959895 + TCGA-HU-A4GU-01 COSM4074732 c.942G>A p.S314S Substitution - coding silent 19:13959202-13959202 + ESCC_18 COSM5626090 c.1650C>T p.S550S Substitution - coding silent 19:13960483-13960483 + TCGA-AH-6644-01 COSM3422454 c.52G>A p.G18S Substitution - Missense 19:13952564-13952564 + 585208 COSM325120 c.1556T>A p.V519E Substitution - Missense 19:13960316-13960316 + TCGA-60-2712-01 COSM709820 c.836C>T p.A279V Substitution - Missense 19:13959096-13959096 + I2L-P19Ta-Tumor-Biopsy COSM5365068 c.837G>A p.A279A Substitution - coding silent 19:13959097-13959097 + 523-02-5TD COSM5418270 c.602G>A p.R201Q Substitution - Missense 19:13956251-13956251 + T3262 COSM4676354 c.629A>G p.Q210R Substitution - Missense 19:13956367-13956367 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.443627;Hs.443636 19p13.12

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A G Missense p.N455S c.1364A>G 19 14070631 LUSC A G Synonymous p.A76A c.228A>G 19 14065247 UCEC A G Synonymous p.T447T c.1341A>G 19 14070608 OV A T Missense p.Q223L c.668A>T 19 14067218 UCEC C G Synonymous p.T94T c.282C>G 19 14065389 LUSC C T Missense p.A279V c.836C>T 19 14069908 LUSC C T Missense p.P277L c.830C>T 19 14069902 LUSC C T Missense p.R88C c.262C>T 19 14065369 ESCA C T Nonsense p.R509* c.1525C>T 19 14070880 NB C T Synonymous p.A331A c.993C>T 19 14070065 CM C T Synonymous p.F499F c.1497C>T 19 14070852 BLCA C T Synonymous p.L508L c.1524C>T 19 14070879 HNSC G A Missense p.R201Q c.602G>A 19 14067063 CLL G A Missense p.S95N c.284G>A 19 14065391 GBM G A Synonymous p.A279A c.837G>A 19 14069909 HNSC G A Synonymous p.P404P c.1212G>A 19 14070284 HNSC G C Synonymous p.L536L c.1608G>C 19 14071180 GBM T A Missense p.V519E c.1556T>A 19 14071128 SCLC T C Missense p.C267R c.799T>C 19 14069871 ESCA T C Synonymous p.S265S c.795T>C 19 14069867 HNSC