Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 19 1993163 1993163 + Silent SNP C C T TCGA-OR-A5JF-01A-11D-A29I-10 TCGA-OR-A5JF-10A-01D-A29L-10 g.chr19:1993163C>T c.540G>A c.(538-540)tcG>tcA p.S180S BLCA 19 1986490 1986490 + Silent SNP G G C TCGA-HQ-A5NE-01A-12D-A289-08 TCGA-HQ-A5NE-10A-01D-A289-08 g.chr19:1986490G>C c.1575C>G c.(1573-1575)acC>acG p.T525T BLCA 19 1986587 1986587 + Missense_Mutation SNP G G A TCGA-DK-AA71-01A-31D-A391-08 TCGA-DK-AA71-10A-01D-A394-08 g.chr19:1986587G>A c.1478C>T c.(1477-1479)aCg>aTg p.T493M BLCA 19 1986969 1986969 + Missense_Mutation SNP G G C TCGA-DK-A6B2-01A-11D-A30E-08 TCGA-DK-A6B2-10A-01D-A30H-08 g.chr19:1986969G>C c.1276C>G c.(1276-1278)Cac>Gac p.H426D BLCA 19 1990104 1990104 + Missense_Mutation SNP C C A TCGA-4Z-AA7O-01A-31D-A391-08 TCGA-4Z-AA7O-10A-01D-A394-08 g.chr19:1990104C>A c.887G>T c.(886-888)cGg>cTg p.R296L BLCA 19 1993151 1993151 + Missense_Mutation SNP C C G TCGA-DK-A3IU-01A-11D-A20D-08 TCGA-DK-A3IU-10A-01D-A20D-08 g.chr19:1993151C>G c.552G>C c.(550-552)caG>caC p.Q184H BLCA 19 2015370 2015370 + Missense_Mutation SNP G G T TCGA-DK-A3IT-01A-31D-A20D-08 TCGA-DK-A3IT-10A-01D-A20D-08 g.chr19:2015370G>T c.333C>A c.(331-333)ttC>ttA p.F111L BLCA 19 2015432 2015432 + Nonsense_Mutation SNP C C A TCGA-GD-A6C6-01A-21D-A31L-08 TCGA-GD-A6C6-10A-01D-A31J-08 g.chr19:2015432C>A c.271G>T c.(271-273)Gag>Tag p.E91* COAD 19 1987553 1987553 + Missense_Mutation SNP C C T TCGA-A6-6781-01A-22D-1924-10 TCGA-A6-6781-10A-01D-1924-10 g.chr19:1987553C>T c.1127G>A c.(1126-1128)cGc>cAc p.R376H COAD 19 1987553 1987553 + Missense_Mutation SNP C C T TCGA-G4-6317-01A-11D-1719-10 TCGA-G4-6317-10A-01D-1720-10 g.chr19:1987553C>T c.1127G>A c.(1126-1128)cGc>cAc p.R376H COAD 19 1987636 1987636 + Missense_Mutation SNP G G T TCGA-G4-6628-01A-11D-1835-10 TCGA-G4-6628-10A-01D-1835-10 g.chr19:1987636G>T c.1044C>A c.(1042-1044)caC>caA p.H348Q COAD 19 1990031 1990031 + Silent SNP C C T TCGA-AA-3947-01A-01W-0995-10 TCGA-AA-3947-10A-01W-0995-10 g.chr19:1990031C>T c.960G>A c.(958-960)ccG>ccA p.P320P COAD 19 1990741 1990741 + Silent SNP C C T TCGA-CM-5861-01A-01D-1650-10 TCGA-CM-5861-10A-01D-1650-10 g.chr19:1990741C>T c.765G>A c.(763-765)gcG>gcA p.A255A COAD 19 1997458 1997458 + Missense_Mutation SNP C C T TCGA-DM-A1HB-01A-21D-A183-10 TCGA-DM-A1HB-10A-01D-A183-10 g.chr19:1997458C>T c.412G>A c.(412-414)Gtg>Atg p.V138M COADREAD 19 1987553 1987553 + Missense_Mutation SNP C C T TCGA-A6-6781-01A-22D-1924-10 TCGA-A6-6781-10A-01D-1924-10 g.chr19:1987553C>T c.1127G>A c.(1126-1128)cGc>cAc p.R376H COADREAD 19 1987553 1987553 + Missense_Mutation SNP C C T TCGA-G4-6317-01A-11D-1719-10 TCGA-G4-6317-10A-01D-1720-10 g.chr19:1987553C>T c.1127G>A c.(1126-1128)cGc>cAc p.R376H COADREAD 19 1987636 1987636 + Missense_Mutation SNP G G T TCGA-G4-6628-01A-11D-1835-10 TCGA-G4-6628-10A-01D-1835-10 g.chr19:1987636G>T c.1044C>A c.(1042-1044)caC>caA p.H348Q COADREAD 19 1990031 1990031 + Silent SNP C C T TCGA-AA-3947-01A-01W-0995-10 TCGA-AA-3947-10A-01W-0995-10 g.chr19:1990031C>T c.960G>A c.(958-960)ccG>ccA p.P320P COADREAD 19 1990741 1990741 + Silent SNP C C T TCGA-CM-5861-01A-01D-1650-10 TCGA-CM-5861-10A-01D-1650-10 g.chr19:1990741C>T c.765G>A c.(763-765)gcG>gcA p.A255A COADREAD 19 1997458 1997458 + Missense_Mutation SNP C C T TCGA-DM-A1HB-01A-21D-A183-10 TCGA-DM-A1HB-10A-01D-A183-10 g.chr19:1997458C>T c.412G>A c.(412-414)Gtg>Atg p.V138M ESCA 19 1990135 1990135 + Missense_Mutation SNP C C T TCGA-L5-A8NE-01A-11D-A37C-09 TCGA-L5-A8NE-11A-11D-A37F-09 g.chr19:1990135C>T c.856G>A c.(856-858)Gtt>Att p.V286I GBMLGG 19 1987539 1987539 + Missense_Mutation SNP C C T TCGA-DU-A5TY-01A-11D-A289-08 TCGA-DU-A5TY-10A-01D-A289-08 g.chr19:1987539C>T c.1141G>A c.(1141-1143)Gag>Aag p.E381K GBMLGG 19 1987624 1987624 + Missense_Mutation SNP G G T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr19:1987624G>T c.1056C>A c.(1054-1056)aaC>aaA p.N352K HNSC 19 1986864 1986864 + Missense_Mutation SNP G G A TCGA-F7-A624-01A-22D-A30E-08 TCGA-F7-A624-10A-01D-A30H-08 g.chr19:1986864G>A c.1381C>T c.(1381-1383)Ccc>Tcc p.P461S HNSC 19 1987221 1987221 + Missense_Mutation SNP C C T TCGA-D6-6516-01A-11D-1870-08 TCGA-D6-6516-10A-01D-1870-08 g.chr19:1987221C>T c.1213G>A c.(1213-1215)Gga>Aga p.G405R HNSC 19 1990034 1990034 + Silent SNP G G A TCGA-TN-A7HL-01A-11D-A34J-08 TCGA-TN-A7HL-10A-01D-A34M-08 g.chr19:1990034G>A c.957C>T c.(955-957)ttC>ttT p.F319F HNSC 19 1993106 1993106 + Silent SNP C C T TCGA-CV-7432-01A-11D-2129-08 TCGA-CV-7432-10A-01D-2129-08 g.chr19:1993106C>T c.597G>A c.(595-597)aaG>aaA p.K199K HNSC 19 1993166 1993166 + Nonsense_Mutation SNP G G C TCGA-CN-6994-01A-11D-1912-08 TCGA-CN-6994-10A-01D-1912-08 g.chr19:1993166G>C c.537C>G c.(535-537)taC>taG p.Y179* KIPAN 19 1986502 1986502 + Silent SNP G G A TCGA-CZ-4854-01A-01D-1373-10 TCGA-CZ-4854-11A-01D-1373-10 g.chr19:1986502G>A c.1563C>T c.(1561-1563)gtC>gtT p.V521V KIPAN 19 1986877 1986877 + Silent SNP C C G TCGA-BQ-5877-01A-11D-1589-08 TCGA-BQ-5877-11A-01D-1589-08 g.chr19:1986877C>G c.1368G>C c.(1366-1368)ccG>ccC p.P456P KIPAN 19 1993133 1993133 + Silent SNP C C T TCGA-BP-4967-01A-01D-1462-08 TCGA-BP-4967-11A-01D-1462-08 g.chr19:1993133C>T c.570G>A c.(568-570)gtG>gtA p.V190V KIRC 19 1986502 1986502 + Silent SNP G G A TCGA-CZ-4854-01A-01D-1373-10 TCGA-CZ-4854-11A-01D-1373-10 g.chr19:1986502G>A c.1563C>T c.(1561-1563)gtC>gtT p.V521V KIRC 19 1993133 1993133 + Silent SNP C C T TCGA-BP-4967-01A-01D-1462-08 TCGA-BP-4967-11A-01D-1462-08 g.chr19:1993133C>T c.570G>A c.(568-570)gtG>gtA p.V190V KIRP 19 1986877 1986877 + Silent SNP C C G TCGA-BQ-5877-01A-11D-1589-08 TCGA-BQ-5877-11A-01D-1589-08 g.chr19:1986877C>G c.1368G>C c.(1366-1368)ccG>ccC p.P456P LGG 19 1987539 1987539 + Missense_Mutation SNP C C T TCGA-DU-A5TY-01A-11D-A289-08 TCGA-DU-A5TY-10A-01D-A289-08 g.chr19:1987539C>T c.1141G>A c.(1141-1143)Gag>Aag p.E381K LGG 19 1987624 1987624 + Missense_Mutation SNP G G T TCGA-DU-6392-01A-11D-1705-08 TCGA-DU-6392-10A-01D-1705-08 g.chr19:1987624G>T c.1056C>A c.(1054-1056)aaC>aaA p.N352K LUAD 19 1986642 1986642 + Missense_Mutation SNP C C T TCGA-50-6592-01A-11D-1753-08 TCGA-50-6592-11A-01D-1753-08 g.chr19:1986642C>T c.1423G>A c.(1423-1425)Gac>Aac p.D475N LUAD 19 1987200 1987200 + Missense_Mutation SNP T T G TCGA-95-7567-01A-11D-2063-08 TCGA-95-7567-10A-01D-2063-08 g.chr19:1987200T>G c.1234A>C c.(1234-1236)Atc>Ctc p.I412L OV 19 1997416 1997416 + Missense_Mutation SNP C C T TCGA-13-1506-01A-01W-0549-09 TCGA-13-1506-10A-01W-0550-09 g.chr19:1997416C>T c.454G>A c.(454-456)Ggg>Agg p.G152R PAAD 19 1986857 1986857 + Missense_Mutation SNP A A G TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr19:1986857A>G c.1388T>C c.(1387-1389)gTc>gCc p.V463A PAAD 19 1990071 1990071 + Missense_Mutation SNP C C T TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr19:1990071C>T c.920G>A c.(919-921)cGg>cAg p.R307Q PRAD 19 1986928 1986928 + Silent SNP G G A TCGA-EJ-A46F-01A-31D-A257-08 TCGA-EJ-A46F-10A-01D-A25A-08 g.chr19:1986928G>A c.1317C>T c.(1315-1317)ggC>ggT p.G439G PRAD 19 1987589 1987589 + Missense_Mutation SNP C C T TCGA-XK-AAIW-01A-11D-A41K-08 TCGA-XK-AAIW-10A-01D-A41N-08 g.chr19:1987589C>T c.1091G>A c.(1090-1092)cGc>cAc p.R364H PRAD 19 1990006 1990006 + Missense_Mutation SNP C C T TCGA-XK-AAIW-01A-11D-A41K-08 TCGA-XK-AAIW-10A-01D-A41N-08 g.chr19:1990006C>T c.985G>A c.(985-987)Gca>Aca p.A329T SKCM 19 1986899 1986899 + Missense_Mutation SNP A A C TCGA-D3-A3MV-06A-11D-A21A-08 TCGA-D3-A3MV-10A-01D-A21A-08 g.chr19:1986899A>C c.1346T>G c.(1345-1347)tTc>tGc p.F449C SKCM 19 1997393 1997393 + Silent SNP C C T TCGA-D9-A149-06A-11D-A196-08 TCGA-D9-A149-10A-01D-A198-08 g.chr19:1997393C>T c.477G>A c.(475-477)acG>acA p.T159T

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-US 19 1993151 1993151 single base substitution C G 3_prime_UTR_variant BLCA-US 19 1993151 1993151 single base substitution C G downstream_gene_variant BLCA-US 19 1993151 1993151 single base substitution C G exon_variant BLCA-US 19 1993151 1993151 single base substitution C G missense_variant Q184H 552G>C BLCA-US 19 1993151 1993151 single base substitution C G missense_variant Q35H 105G>C BLCA-US 19 1993151 1993151 single base substitution C G upstream_gene_variant BOCA-FR 19 1986287 1986287 single base substitution G A 3_prime_UTR_variant BOCA-FR 19 1986287 1986287 single base substitution G A downstream_gene_variant BOCA-FR 19 1986287 1986287 single base substitution G A exon_variant BRCA-EU 19 1980858 1980858 single base substitution C T downstream_gene_variant BRCA-EU 19 1981005 1981005 single base substitution G T downstream_gene_variant BRCA-EU 19 1982160 1982160 single base substitution G A downstream_gene_variant BRCA-EU 19 1985143 1985143 single base substitution A T downstream_gene_variant BRCA-EU 19 1985808 1985808 single base substitution T C 3_prime_UTR_variant BRCA-EU 19 1985808 1985808 single base substitution T C downstream_gene_variant BRCA-EU 19 1985808 1985808 single base substitution T C exon_variant BRCA-EU 19 1986676 1986676 single base substitution C G downstream_gene_variant BRCA-EU 19 1986676 1986676 single base substitution C G intron_variant BRCA-EU 19 1986896 1986896 single base substitution C T downstream_gene_variant BRCA-EU 19 1986896 1986896 single base substitution C T exon_variant BRCA-EU 19 1986896 1986896 single base substitution C T missense_variant R450H 1349G>A BRCA-EU 19 1988177 1988177 single base substitution C T downstream_gene_variant BRCA-EU 19 1988177 1988177 single base substitution C T exon_variant BRCA-EU 19 1988177 1988177 single base substitution C T intron_variant BRCA-EU 19 1988462 1988462 single base substitution G A downstream_gene_variant BRCA-EU 19 1988462 1988462 single base substitution G A exon_variant BRCA-EU 19 1988462 1988462 single base substitution G A intron_variant BRCA-EU 19 1988522 1988522 single base substitution G A downstream_gene_variant BRCA-EU 19 1988522 1988522 single base substitution G A exon_variant BRCA-EU 19 1988522 1988522 single base substitution G A intron_variant BRCA-EU 19 1988605 1988605 single base substitution C T downstream_gene_variant BRCA-EU 19 1988605 1988605 single base substitution C T intron_variant BRCA-EU 19 1988605 1988605 single base substitution C T upstream_gene_variant BRCA-EU 19 1988821 1988821 single base substitution C T downstream_gene_variant BRCA-EU 19 1988821 1988821 single base substitution C T intron_variant BRCA-EU 19 1988821 1988821 single base substitution C T upstream_gene_variant BRCA-EU 19 1988861 1988861 single base substitution C G downstream_gene_variant BRCA-EU 19 1988861 1988861 single base substitution C G intron_variant BRCA-EU 19 1988861 1988861 single base substitution C G upstream_gene_variant BRCA-EU 19 1988963 1988963 single base substitution G C downstream_gene_variant BRCA-EU 19 1988963 1988963 single base substitution G C intron_variant BRCA-EU 19 1988963 1988963 single base substitution G C upstream_gene_variant BRCA-EU 19 1989309 1989309 single base substitution G C downstream_gene_variant BRCA-EU 19 1989309 1989309 single base substitution G C intron_variant BRCA-EU 19 1989309 1989309 single base substitution G C upstream_gene_variant BRCA-EU 19 1990440 1990440 single base substitution C G downstream_gene_variant BRCA-EU 19 1990440 1990440 single base substitution C G intron_variant BRCA-EU 19 1990440 1990440 single base substitution C G upstream_gene_variant BRCA-EU 19 1990897 1990897 single base substitution G A downstream_gene_variant BRCA-EU 19 1990897 1990897 single base substitution G A exon_variant BRCA-EU 19 1990897 1990897 single base substitution G A intron_variant BRCA-EU 19 1990897 1990897 single base substitution G A upstream_gene_variant BRCA-EU 19 1991123 1991123 single base substitution G A downstream_gene_variant BRCA-EU 19 1991123 1991123 single base substitution G A exon_variant BRCA-EU 19 1991123 1991123 single base substitution G A intron_variant BRCA-EU 19 1991123 1991123 single base substitution G A upstream_gene_variant BRCA-EU 19 1991385 1991385 single base substitution C T downstream_gene_variant BRCA-EU 19 1991385 1991385 single base substitution C T intron_variant BRCA-EU 19 1991385 1991385 single base substitution C T upstream_gene_variant BRCA-EU 19 1992270 1992270 deletion of <=200bp T - downstream_gene_variant BRCA-EU 19 1992270 1992270 deletion of <=200bp T - intron_variant BRCA-EU 19 1992270 1992270 deletion of <=200bp T - upstream_gene_variant BRCA-EU 19 1993056 1993058 deletion of <=200bp TTC - 3_prime_UTR_variant BRCA-EU 19 1993056 1993058 deletion of <=200bp TTC - disruptive_inframe_deletion KN215N BRCA-EU 19 1993056 1993058 deletion of <=200bp TTC - disruptive_inframe_deletion KN66N BRCA-EU 19 1993056 1993058 deletion of <=200bp TTC - downstream_gene_variant BRCA-EU 19 1993056 1993058 deletion of <=200bp TTC - upstream_gene_variant BRCA-EU 19 1994426 1994426 single base substitution G C downstream_gene_variant BRCA-EU 19 1994426 1994426 single base substitution G C intron_variant BRCA-EU 19 1994426 1994426 single base substitution G C upstream_gene_variant BRCA-EU 19 1994428 1994428 single base substitution A G downstream_gene_variant BRCA-EU 19 1994428 1994428 single base substitution A G intron_variant BRCA-EU 19 1994428 1994428 single base substitution A G upstream_gene_variant BRCA-EU 19 1996027 1996027 single base substitution A G downstream_gene_variant BRCA-EU 19 1996027 1996027 single base substitution A G intron_variant BRCA-EU 19 1996027 1996027 single base substitution A G upstream_gene_variant BRCA-EU 19 1996333 1996333 insertion of <=200bp - A downstream_gene_variant BRCA-EU 19 1996333 1996333 insertion of <=200bp - A intron_variant BRCA-EU 19 1996866 1996866 single base substitution G A downstream_gene_variant BRCA-EU 19 1996866 1996866 single base substitution G A intron_variant BRCA-EU 19 1996995 1996995 single base substitution A G downstream_gene_variant BRCA-EU 19 1996995 1996995 single base substitution A G intron_variant BRCA-EU 19 1997721 1997721 single base substitution C T intron_variant BRCA-EU 19 1997721 1997721 single base substitution C T upstream_gene_variant BRCA-EU 19 1998436 1998436 single base substitution G A intron_variant BRCA-EU 19 1998436 1998436 single base substitution G A upstream_gene_variant BRCA-EU 19 2000073 2000073 single base substitution G T intron_variant BRCA-EU 19 2000073 2000073 single base substitution G T upstream_gene_variant BRCA-EU 19 2005258 2005258 single base substitution G T intron_variant BRCA-EU 19 2006101 2006101 single base substitution A C intron_variant BRCA-EU 19 2007250 2007250 insertion of <=200bp - A intron_variant BRCA-EU 19 2007934 2007934 single base substitution G T intron_variant BRCA-EU 19 2008449 2008449 single base substitution C G intron_variant BRCA-EU 19 2010151 2010151 deletion of <=200bp A - intron_variant BRCA-EU 19 2011091 2011091 single base substitution G A intron_variant BRCA-EU 19 2011711 2011711 single base substitution C T intron_variant BRCA-EU 19 2014465 2014465 single base substitution G T intron_variant BRCA-EU 19 2016414 2016414 single base substitution C G intron_variant BRCA-EU 19 2016414 2016414 single base substitution C G upstream_gene_variant BRCA-EU 19 2016853 2016853 single base substitution C T intron_variant BRCA-EU 19 2016853 2016853 single base substitution C T upstream_gene_variant BRCA-EU 19 2018059 2018059 single base substitution T A intron_variant BRCA-EU 19 2018059 2018059 single base substitution T A upstream_gene_variant BRCA-EU 19 2019764 2019764 single base substitution A G intron_variant BRCA-EU 19 2019764 2019764 single base substitution A G upstream_gene_variant BRCA-EU 19 2019840 2019840 single base substitution T G intron_variant BRCA-EU 19 2019840 2019840 single base substitution T G upstream_gene_variant BRCA-EU 19 2020473 2020473 single base substitution T A intron_variant BRCA-EU 19 2020473 2020473 single base substitution T A upstream_gene_variant BRCA-EU 19 2022390 2022390 single base substitution G C intron_variant BRCA-EU 19 2022761 2022761 single base substitution C A intron_variant BRCA-EU 19 2022961 2022961 single base substitution G A intron_variant BRCA-EU 19 2023083 2023083 single base substitution G C intron_variant BRCA-EU 19 2023303 2023303 single base substitution C G intron_variant BRCA-EU 19 2023762 2023762 single base substitution G T intron_variant BRCA-EU 19 2025403 2025403 single base substitution C A intron_variant BRCA-EU 19 2025590 2025590 single base substitution G C intron_variant BRCA-EU 19 2026418 2026418 single base substitution G A intron_variant BRCA-EU 19 2026846 2026846 insertion of <=200bp - G intron_variant BRCA-EU 19 2027566 2027566 single base substitution A G intron_variant BRCA-EU 19 2030249 2030249 single base substitution T G intron_variant BRCA-EU 19 2030367 2030367 single base substitution G A intron_variant BRCA-EU 19 2031875 2031875 single base substitution G A intron_variant BRCA-EU 19 2032773 2032773 single base substitution C T intron_variant BRCA-EU 19 2034692 2034692 single base substitution C G intron_variant BRCA-EU 19 2035892 2035892 single base substitution A G upstream_gene_variant BRCA-EU 19 2035915 2035915 single base substitution G A upstream_gene_variant BRCA-EU 19 2036560 2036562 deletion of <=200bp AAG - upstream_gene_variant BRCA-EU 19 2038247 2038247 deletion of <=200bp T - upstream_gene_variant BRCA-EU 19 2038247 2038247 insertion of <=200bp - T upstream_gene_variant BRCA-EU 19 2038941 2038941 single base substitution A G upstream_gene_variant BRCA-EU 19 2038992 2038992 single base substitution G T upstream_gene_variant BRCA-FR 19 1980858 1980858 single base substitution C T downstream_gene_variant BRCA-FR 19 1988522 1988522 single base substitution G A downstream_gene_variant BRCA-FR 19 1988522 1988522 single base substitution G A exon_variant BRCA-FR 19 1988522 1988522 single base substitution G A intron_variant BRCA-FR 19 2016853 2016853 single base substitution C T intron_variant BRCA-FR 19 2016853 2016853 single base substitution C T upstream_gene_variant BRCA-FR 19 2020186 2020186 single base substitution G A intron_variant BRCA-FR 19 2020186 2020186 single base substitution G A upstream_gene_variant BRCA-FR 19 2035915 2035915 single base substitution G A upstream_gene_variant BRCA-KR 19 2039690 2039690 single base substitution G T upstream_gene_variant BRCA-UK 19 1988605 1988605 single base substitution C T downstream_gene_variant BRCA-UK 19 1988605 1988605 single base substitution C T intron_variant BRCA-UK 19 1988605 1988605 single base substitution C T upstream_gene_variant BRCA-UK 19 1989153 1989153 single base substitution G A downstream_gene_variant BRCA-UK 19 1989153 1989153 single base substitution G A intron_variant BRCA-UK 19 1989153 1989153 single base substitution G A upstream_gene_variant BRCA-UK 19 2023762 2023762 single base substitution G T intron_variant BRCA-UK 19 2030249 2030249 single base substitution T G intron_variant BRCA-UK 19 2032486 2032486 single base substitution C T intron_variant BRCA-UK 19 2032645 2032645 single base substitution A T intron_variant BRCA-US 19 2039659 2039659 deletion of <=200bp C - upstream_gene_variant BTCA-JP 19 1980473 1980473 deletion of <=200bp A - downstream_gene_variant BTCA-JP 19 1993128 1993128 single base substitution G A 3_prime_UTR_variant BTCA-JP 19 1993128 1993128 single base substitution G A downstream_gene_variant BTCA-JP 19 1993128 1993128 single base substitution G A exon_variant BTCA-JP 19 1993128 1993128 single base substitution G A missense_variant T192I 575C>T BTCA-JP 19 1993128 1993128 single base substitution G A missense_variant T43I 128C>T BTCA-JP 19 1993128 1993128 single base substitution G A upstream_gene_variant BTCA-JP 19 1993257 1993257 single base substitution G A downstream_gene_variant BTCA-JP 19 1993257 1993257 single base substitution G A intron_variant BTCA-JP 19 1993257 1993257 single base substitution G A upstream_gene_variant BTCA-JP 19 2037834 2037834 single base substitution G A upstream_gene_variant CLLE-ES 19 1987742 1987742 single base substitution C A downstream_gene_variant CLLE-ES 19 1987742 1987742 single base substitution C A exon_variant CLLE-ES 19 1987742 1987742 single base substitution C A intron_variant CLLE-ES 19 2019694 2019694 single base substitution G C intron_variant CLLE-ES 19 2019694 2019694 single base substitution G C upstream_gene_variant CLLE-ES 19 2034619 2034619 single base substitution G A intron_variant COAD-US 19 1987553 1987553 single base substitution C T downstream_gene_variant COAD-US 19 1987553 1987553 single base substitution C T exon_variant COAD-US 19 1987553 1987553 single base substitution C T missense_variant R287H 860G>A COAD-US 19 1987553 1987553 single base substitution C T missense_variant R376H 1127G>A COAD-US 19 1987636 1987636 single base substitution G T downstream_gene_variant COAD-US 19 1987636 1987636 single base substitution G T exon_variant COAD-US 19 1987636 1987636 single base substitution G T missense_variant H259Q 777C>A COAD-US 19 1987636 1987636 single base substitution G T missense_variant H348Q 1044C>A COAD-US 19 1990741 1990741 single base substitution C T 3_prime_UTR_variant COAD-US 19 1990741 1990741 single base substitution C T downstream_gene_variant COAD-US 19 1990741 1990741 single base substitution C T exon_variant COAD-US 19 1990741 1990741 single base substitution C T synonymous_variant A166A 498G>A COAD-US 19 1990741 1990741 single base substitution C T synonymous_variant A255A 765G>A COAD-US 19 1990741 1990741 single base substitution C T upstream_gene_variant COAD-US 19 1997363 1997363 single base substitution A G 3_prime_UTR_variant COAD-US 19 1997363 1997363 single base substitution A G exon_variant COAD-US 19 1997363 1997363 single base substitution A G synonymous_variant A169A 507T>C COAD-US 19 1997363 1997363 single base substitution A G synonymous_variant A20A 60T>C COAD-US 19 1997441 1997441 single base substitution G A 3_prime_UTR_variant COAD-US 19 1997441 1997441 single base substitution G A exon_variant COAD-US 19 1997441 1997441 single base substitution G A synonymous_variant S143S 429C>T COAD-US 19 1997441 1997441 single base substitution G A upstream_gene_variant COCA-CN 19 1980454 1980454 single base substitution T G downstream_gene_variant COCA-CN 19 1986449 1986449 single base substitution A G 3_prime_UTR_variant COCA-CN 19 1986449 1986449 single base substitution A G downstream_gene_variant COCA-CN 19 1986449 1986449 single base substitution A G exon_variant COCA-CN 19 1986825 1986825 single base substitution G A downstream_gene_variant COCA-CN 19 1986825 1986825 single base substitution G A splice_region_variant COCA-CN 19 1987386 1987386 single base substitution G A downstream_gene_variant COCA-CN 19 1987386 1987386 single base substitution G A exon_variant COCA-CN 19 1987386 1987386 single base substitution G A intron_variant COCA-CN 19 1987578 1987578 single base substitution G A downstream_gene_variant COCA-CN 19 1987578 1987578 single base substitution G A exon_variant COCA-CN 19 1987578 1987578 single base substitution G A missense_variant R279C 835C>T COCA-CN 19 1987578 1987578 single base substitution G A missense_variant R368C 1102C>T COCA-CN 19 1990129 1990129 single base substitution G A 3_prime_UTR_variant COCA-CN 19 1990129 1990129 single base substitution G A downstream_gene_variant COCA-CN 19 1990129 1990129 single base substitution G A exon_variant COCA-CN 19 1990129 1990129 single base substitution G A missense_variant R199C 595C>T COCA-CN 19 1990129 1990129 single base substitution G A missense_variant R288C 862C>T COCA-CN 19 1990129 1990129 single base substitution G A upstream_gene_variant COCA-CN 19 2037047 2037047 single base substitution A G upstream_gene_variant COCA-CN 19 2037842 2037842 single base substitution A C upstream_gene_variant EOPC-DE 19 2010640 2010640 single base substitution A C intron_variant EOPC-DE 19 2025470 2025470 single base substitution C T intron_variant EOPC-DE 19 2031043 2031043 single base substitution G A intron_variant ESAD-UK 19 1986596 1986596 single base substitution G A downstream_gene_variant ESAD-UK 19 1986596 1986596 single base substitution G A exon_variant ESAD-UK 19 1986596 1986596 single base substitution G A missense_variant S490L 1469C>T ESAD-UK 19 1988771 1988771 single base substitution C A downstream_gene_variant ESAD-UK 19 1988771 1988771 single base substitution C A intron_variant ESAD-UK 19 1988771 1988771 single base substitution C A upstream_gene_variant ESAD-UK 19 1988914 1988914 single base substitution T C downstream_gene_variant ESAD-UK 19 1988914 1988914 single base substitution T C intron_variant ESAD-UK 19 1988914 1988914 single base substitution T C upstream_gene_variant ESAD-UK 19 1991773 1991773 single base substitution C T downstream_gene_variant ESAD-UK 19 1991773 1991773 single base substitution C T intron_variant ESAD-UK 19 1991773 1991773 single base substitution C T upstream_gene_variant ESAD-UK 19 1993307 1993307 single base substitution C G downstream_gene_variant ESAD-UK 19 1993307 1993307 single base substitution C G intron_variant ESAD-UK 19 1993307 1993307 single base substitution C G upstream_gene_variant ESAD-UK 19 1996461 1996461 single base substitution C G downstream_gene_variant ESAD-UK 19 1996461 1996461 single base substitution C G intron_variant ESAD-UK 19 1996478 1996478 deletion of <=200bp T - downstream_gene_variant ESAD-UK 19 1996478 1996478 deletion of <=200bp T - intron_variant ESAD-UK 19 1996997 1996997 single base substitution T C downstream_gene_variant ESAD-UK 19 1996997 1996997 single base substitution T C intron_variant ESAD-UK 19 1997052 1997052 single base substitution G C downstream_gene_variant ESAD-UK 19 1997052 1997052 single base substitution G C intron_variant ESAD-UK 19 1997831 1997831 single base substitution G A intron_variant ESAD-UK 19 1997831 1997831 single base substitution G A upstream_gene_variant ESAD-UK 19 1998863 1998863 single base substitution G A intron_variant ESAD-UK 19 1998863 1998863 single base substitution G A upstream_gene_variant ESAD-UK 19 1998948 1998948 single base substitution G A intron_variant ESAD-UK 19 1998948 1998948 single base substitution G A upstream_gene_variant ESAD-UK 19 1999457 1999457 single base substitution G T intron_variant ESAD-UK 19 1999457 1999457 single base substitution G T upstream_gene_variant ESAD-UK 19 2000192 2000192 deletion of <=200bp C - intron_variant ESAD-UK 19 2000192 2000192 deletion of <=200bp C - upstream_gene_variant ESAD-UK 19 2000219 2000219 single base substitution G T intron_variant ESAD-UK 19 2000219 2000219 single base substitution G T upstream_gene_variant ESAD-UK 19 2001825 2001825 single base substitution C G intron_variant ESAD-UK 19 2001825 2001825 single base substitution C G upstream_gene_variant ESAD-UK 19 2005744 2005744 single base substitution G A intron_variant ESAD-UK 19 2009580 2009580 single base substitution G A intron_variant ESAD-UK 19 2010514 2010514 single base substitution G A intron_variant ESAD-UK 19 2012717 2012717 deletion of <=200bp C - intron_variant ESAD-UK 19 2014809 2014809 single base substitution C A intron_variant ESAD-UK 19 2017156 2017156 single base substitution A C intron_variant ESAD-UK 19 2017156 2017156 single base substitution A C upstream_gene_variant ESAD-UK 19 2018267 2018267 single base substitution G T intron_variant ESAD-UK 19 2018267 2018267 single base substitution G T upstream_gene_variant ESAD-UK 19 2023586 2023586 single base substitution G A intron_variant ESAD-UK 19 2026334 2026334 single base substitution C G intron_variant ESAD-UK 19 2029882 2029882 single base substitution G A intron_variant ESAD-UK 19 2036659 2036659 single base substitution C T upstream_gene_variant ESAD-UK 19 2037842 2037842 single base substitution A C upstream_gene_variant ESAD-UK 19 2039676 2039676 single base substitution G A upstream_gene_variant ESCA-CN 19 1986876 1986876 single base substitution C T downstream_gene_variant ESCA-CN 19 1986876 1986876 single base substitution C T exon_variant ESCA-CN 19 1986876 1986876 single base substitution C T missense_variant V457M 1369G>A ESCA-CN 19 1997363 1997363 single base substitution A G 3_prime_UTR_variant ESCA-CN 19 1997363 1997363 single base substitution A G exon_variant ESCA-CN 19 1997363 1997363 single base substitution A G synonymous_variant A169A 507T>C ESCA-CN 19 1997363 1997363 single base substitution A G synonymous_variant A20A 60T>C KIRC-US 19 1986502 1986502 single base substitution G A downstream_gene_variant KIRC-US 19 1986502 1986502 single base substitution G A exon_variant KIRC-US 19 1986502 1986502 single base substitution G A synonymous_variant V521V 1563C>T KIRC-US 19 1993133 1993133 single base substitution C T 3_prime_UTR_variant KIRC-US 19 1993133 1993133 single base substitution C T downstream_gene_variant KIRC-US 19 1993133 1993133 single base substitution C T exon_variant KIRC-US 19 1993133 1993133 single base substitution C T synonymous_variant V190V 570G>A KIRC-US 19 1993133 1993133 single base substitution C T synonymous_variant V41V 123G>A KIRC-US 19 1993133 1993133 single base substitution C T upstream_gene_variant KIRP-US 19 1986877 1986877 single base substitution C G downstream_gene_variant KIRP-US 19 1986877 1986877 single base substitution C G exon_variant KIRP-US 19 1986877 1986877 single base substitution C G synonymous_variant P456P 1368G>C KIRP-US 19 1986958 1986958 single base substitution G A downstream_gene_variant KIRP-US 19 1986958 1986958 single base substitution G A exon_variant KIRP-US 19 1986958 1986958 single base substitution G A synonymous_variant S429S 1287C>T KIRP-US 19 2015365 2015365 deletion of <=200bp T - exon_variant KIRP-US 19 2015365 2015365 deletion of <=200bp T - frameshift_variant N113 KIRP-US 19 2015365 2015365 deletion of <=200bp T - intron_variant LAML-KR 19 1983888 1983888 single base substitution A G downstream_gene_variant LAML-KR 19 1987279 1987279 single base substitution C T downstream_gene_variant LAML-KR 19 1987279 1987279 single base substitution C T exon_variant LAML-KR 19 1987279 1987279 single base substitution C T intron_variant LAML-KR 19 1995503 1995503 single base substitution G C downstream_gene_variant LAML-KR 19 1995503 1995503 single base substitution G C intron_variant LAML-KR 19 1995503 1995503 single base substitution G C upstream_gene_variant LAML-KR 19 2031343 2031343 single base substitution G A intron_variant LAML-KR 19 2031345 2031345 single base substitution A G intron_variant LGG-US 19 1987539 1987539 single base substitution C T downstream_gene_variant LGG-US 19 1987539 1987539 single base substitution C T exon_variant LGG-US 19 1987539 1987539 single base substitution C T missense_variant E292K 874G>A LGG-US 19 1987539 1987539 single base substitution C T missense_variant E381K 1141G>A LGG-US 19 2039675 2039675 single base substitution C T upstream_gene_variant LICA-CN 19 1986906 1986906 single base substitution T A downstream_gene_variant LICA-CN 19 1986906 1986906 single base substitution T A exon_variant LICA-CN 19 1986906 1986906 single base substitution T A missense_variant S447C 1339A>T LICA-FR 19 1990820 1990820 single base substitution G T downstream_gene_variant LICA-FR 19 1990820 1990820 single base substitution G T exon_variant LICA-FR 19 1990820 1990820 single base substitution G T missense_variant A140E 419C>A LICA-FR 19 1990820 1990820 single base substitution G T missense_variant A229E 686C>A LICA-FR 19 1990820 1990820 single base substitution G T splice_region_variant LICA-FR 19 1990820 1990820 single base substitution G T upstream_gene_variant LICA-FR 19 1999361 1999361 single base substitution T G intron_variant LICA-FR 19 1999361 1999361 single base substitution T G upstream_gene_variant LICA-FR 19 2034682 2034682 single base substitution T A intron_variant LICA-FR 19 2039145 2039145 single base substitution T C upstream_gene_variant LIHC-US 19 1997425 1997425 single base substitution T C 3_prime_UTR_variant LIHC-US 19 1997425 1997425 single base substitution T C exon_variant LIHC-US 19 1997425 1997425 single base substitution T C missense_variant M149V 445A>G LIHC-US 19 1997425 1997425 single base substitution T C upstream_gene_variant LINC-JP 19 1987398 1987398 single base substitution A G downstream_gene_variant LINC-JP 19 1987398 1987398 single base substitution A G exon_variant LINC-JP 19 1987398 1987398 single base substitution A G intron_variant LINC-JP 19 1999361 1999361 single base substitution T G intron_variant LINC-JP 19 1999361 1999361 single base substitution T G upstream_gene_variant LINC-JP 19 2025056 2025058 deletion of <=200bp TTG - intron_variant LINC-JP 19 2026060 2026060 single base substitution G A intron_variant LINC-JP 19 2026830 2026830 single base substitution G A intron_variant LINC-JP 19 2033158 2033158 single base substitution A T intron_variant LINC-JP 19 2034607 2034607 single base substitution G A intron_variant LINC-JP 19 2036845 2036845 single base substitution T C upstream_gene_variant LINC-JP 19 2037904 2037904 single base substitution G A upstream_gene_variant LIRI-JP 19 1983941 1983941 single base substitution A G downstream_gene_variant LIRI-JP 19 1989611 1989611 single base substitution A T downstream_gene_variant LIRI-JP 19 1989611 1989611 single base substitution A T intron_variant LIRI-JP 19 1989611 1989611 single base substitution A T upstream_gene_variant LIRI-JP 19 1991564 1991564 single base substitution G A downstream_gene_variant LIRI-JP 19 1991564 1991564 single base substitution G A intron_variant LIRI-JP 19 1991564 1991564 single base substitution G A upstream_gene_variant LIRI-JP 19 1997757 1997757 single base substitution A G intron_variant LIRI-JP 19 1997757 1997757 single base substitution A G upstream_gene_variant LIRI-JP 19 2002928 2002928 single base substitution A G intron_variant LIRI-JP 19 2008872 2008872 single base substitution A C intron_variant LIRI-JP 19 2008892 2008892 single base substitution A C intron_variant LIRI-JP 19 2011115 2011115 single base substitution G A intron_variant LIRI-JP 19 2011412 2011412 single base substitution A G intron_variant LIRI-JP 19 2016850 2016850 single base substitution T A intron_variant LIRI-JP 19 2016850 2016850 single base substitution T A upstream_gene_variant LIRI-JP 19 2016976 2016976 single base substitution C T intron_variant LIRI-JP 19 2016976 2016976 single base substitution C T upstream_gene_variant LIRI-JP 19 2017040 2017040 single base substitution G T intron_variant LIRI-JP 19 2017040 2017040 single base substitution G T splice_region_variant LIRI-JP 19 2017040 2017040 single base substitution G T upstream_gene_variant LIRI-JP 19 2017210 2017210 single base substitution G A exon_variant LIRI-JP 19 2017210 2017210 single base substitution G A upstream_gene_variant LIRI-JP 19 2019776 2019776 single base substitution A C intron_variant LIRI-JP 19 2019776 2019776 single base substitution A C upstream_gene_variant LIRI-JP 19 2021652 2021652 single base substitution C A intron_variant LIRI-JP 19 2022251 2022251 single base substitution T C intron_variant LIRI-JP 19 2022583 2022583 single base substitution T C intron_variant LIRI-JP 19 2022851 2022851 single base substitution G T intron_variant LIRI-JP 19 2024537 2024537 single base substitution A C intron_variant LIRI-JP 19 2025556 2025556 single base substitution C G intron_variant LIRI-JP 19 2026279 2026279 single base substitution T C intron_variant LIRI-JP 19 2028033 2028033 single base substitution G C intron_variant LIRI-JP 19 2033325 2033325 single base substitution G T intron_variant LIRI-JP 19 2033634 2033634 single base substitution C A intron_variant LUSC-KR 19 1985573 1985573 single base substitution T G 3_prime_UTR_variant LUSC-KR 19 1985573 1985573 single base substitution T G downstream_gene_variant LUSC-KR 19 1985573 1985573 single base substitution T G exon_variant LUSC-KR 19 1986455 1986455 single base substitution A G 3_prime_UTR_variant LUSC-KR 19 1986455 1986455 single base substitution A G downstream_gene_variant LUSC-KR 19 1986455 1986455 single base substitution A G exon_variant LUSC-KR 19 1995397 1995397 single base substitution C T downstream_gene_variant LUSC-KR 19 1995397 1995397 single base substitution C T intron_variant LUSC-KR 19 1995397 1995397 single base substitution C T upstream_gene_variant LUSC-KR 19 1997363 1997363 single base substitution A G 3_prime_UTR_variant LUSC-KR 19 1997363 1997363 single base substitution A G exon_variant LUSC-KR 19 1997363 1997363 single base substitution A G synonymous_variant A169A 507T>C LUSC-KR 19 1997363 1997363 single base substitution A G synonymous_variant A20A 60T>C LUSC-KR 19 2000525 2000525 single base substitution C G intron_variant LUSC-KR 19 2000525 2000525 single base substitution C G upstream_gene_variant LUSC-KR 19 2001760 2001760 single base substitution G A intron_variant LUSC-KR 19 2001760 2001760 single base substitution G A upstream_gene_variant LUSC-KR 19 2007855 2007855 single base substitution T C intron_variant LUSC-KR 19 2009896 2009896 single base substitution T G intron_variant LUSC-KR 19 2010637 2010637 single base substitution C T intron_variant LUSC-KR 19 2012127 2012127 single base substitution A C intron_variant LUSC-KR 19 2013411 2013411 single base substitution G T intron_variant LUSC-KR 19 2016702 2016702 single base substitution G A intron_variant LUSC-KR 19 2016702 2016702 single base substitution G A upstream_gene_variant LUSC-KR 19 2017543 2017543 single base substitution G C intron_variant LUSC-KR 19 2017543 2017543 single base substitution G C upstream_gene_variant LUSC-KR 19 2017856 2017856 single base substitution C T intron_variant LUSC-KR 19 2017856 2017856 single base substitution C T upstream_gene_variant LUSC-KR 19 2019111 2019111 single base substitution C T intron_variant LUSC-KR 19 2019111 2019111 single base substitution C T upstream_gene_variant LUSC-KR 19 2020147 2020147 single base substitution C A intron_variant LUSC-KR 19 2020147 2020147 single base substitution C A upstream_gene_variant LUSC-KR 19 2023166 2023166 single base substitution C T intron_variant LUSC-KR 19 2024783 2024783 single base substitution C T intron_variant LUSC-KR 19 2025171 2025171 single base substitution C A intron_variant LUSC-KR 19 2026388 2026388 single base substitution C A intron_variant LUSC-KR 19 2027894 2027894 single base substitution G A intron_variant LUSC-KR 19 2030782 2030782 single base substitution C A intron_variant LUSC-KR 19 2034898 2034898 single base substitution C T upstream_gene_variant LUSC-KR 19 2037023 2037023 single base substitution G C upstream_gene_variant LUSC-KR 19 2038661 2038661 single base substitution G C upstream_gene_variant MALY-DE 19 1984586 1984586 single base substitution G A downstream_gene_variant MALY-DE 19 1986553 1986553 single base substitution C T downstream_gene_variant MALY-DE 19 1986553 1986553 single base substitution C T exon_variant MALY-DE 19 1986553 1986553 single base substitution C T synonymous_variant A504A 1512G>A MALY-DE 19 1988177 1988177 single base substitution C T downstream_gene_variant MALY-DE 19 1988177 1988177 single base substitution C T exon_variant MALY-DE 19 1988177 1988177 single base substitution C T intron_variant MALY-DE 19 1991385 1991385 single base substitution C T downstream_gene_variant MALY-DE 19 1991385 1991385 single base substitution C T intron_variant MALY-DE 19 1991385 1991385 single base substitution C T upstream_gene_variant MALY-DE 19 1994755 1994755 single base substitution C G downstream_gene_variant MALY-DE 19 1994755 1994755 single base substitution C G intron_variant MALY-DE 19 1994755 1994755 single base substitution C G upstream_gene_variant MALY-DE 19 2002248 2002249 deletion of <=200bp TG - intron_variant MALY-DE 19 2002248 2002249 deletion of <=200bp TG - upstream_gene_variant MALY-DE 19 2005791 2005791 single base substitution A G intron_variant MALY-DE 19 2013128 2013128 single base substitution A G intron_variant MALY-DE 19 2013157 2013157 single base substitution A T intron_variant MALY-DE 19 2019771 2019771 single base substitution T C intron_variant MALY-DE 19 2019771 2019771 single base substitution T C upstream_gene_variant MALY-DE 19 2027116 2027132 deletion of <=200bp CACACACACCAGACACA - intron_variant MALY-DE 19 2027798 2027798 single base substitution A C intron_variant MALY-DE 19 2029488 2029511 deletion of <=200bp CTTAGTTTGTTACTAAGTTTGTTA - intron_variant MALY-DE 19 2032602 2032602 single base substitution A G intron_variant MALY-DE 19 2034664 2034664 single base substitution A G intron_variant MALY-DE 19 2036388 2036388 single base substitution A C upstream_gene_variant MALY-DE 19 2037014 2037014 insertion of <=200bp - T upstream_gene_variant MALY-DE 19 2037842 2037842 single base substitution A C upstream_gene_variant MALY-DE 19 2038601 2038601 single base substitution G A upstream_gene_variant MELA-AU 19 1980632 1980632 single base substitution T C downstream_gene_variant MELA-AU 19 1980953 1980953 single base substitution C G downstream_gene_variant MELA-AU 19 1981697 1981697 single base substitution C T downstream_gene_variant MELA-AU 19 1981848 1981848 single base substitution C T downstream_gene_variant MELA-AU 19 1982046 1982046 single base substitution C T downstream_gene_variant MELA-AU 19 1982052 1982052 single base substitution C T downstream_gene_variant MELA-AU 19 1982063 1982063 single base substitution C T downstream_gene_variant MELA-AU 19 1982117 1982117 single base substitution C T downstream_gene_variant MELA-AU 19 1982492 1982492 single base substitution A G downstream_gene_variant MELA-AU 19 1984938 1984939 multiple base substitution (>=2bp and <=200bp) CC TT downstream_gene_variant MELA-AU 19 1986460 1986460 single base substitution G A 3_prime_UTR_variant MELA-AU 19 1986460 1986460 single base substitution G A downstream_gene_variant MELA-AU 19 1986460 1986460 single base substitution G A exon_variant MELA-AU 19 1986511 1986511 single base substitution G A downstream_gene_variant MELA-AU 19 1986511 1986511 single base substitution G A exon_variant MELA-AU 19 1986511 1986511 single base substitution G A synonymous_variant I518I 1554C>T MELA-AU 19 1987026 1987026 single base substitution G A downstream_gene_variant MELA-AU 19 1987026 1987026 single base substitution G A intron_variant MELA-AU 19 1987899 1987899 single base substitution C T downstream_gene_variant MELA-AU 19 1987899 1987899 single base substitution C T exon_variant MELA-AU 19 1987899 1987899 single base substitution C T intron_variant MELA-AU 19 1988248 1988248 single base substitution G A downstream_gene_variant MELA-AU 19 1988248 1988248 single base substitution G A exon_variant MELA-AU 19 1988248 1988248 single base substitution G A intron_variant MELA-AU 19 1989592 1989592 single base substitution G A downstream_gene_variant MELA-AU 19 1989592 1989592 single base substitution G A intron_variant MELA-AU 19 1989592 1989592 single base substitution G A upstream_gene_variant MELA-AU 19 1990473 1990473 single base substitution G A downstream_gene_variant MELA-AU 19 1990473 1990473 single base substitution G A intron_variant MELA-AU 19 1990473 1990473 single base substitution G A upstream_gene_variant MELA-AU 19 1990549 1990549 single base substitution G A downstream_gene_variant MELA-AU 19 1990549 1990549 single base substitution G A intron_variant MELA-AU 19 1990549 1990549 single base substitution G A upstream_gene_variant MELA-AU 19 1990626 1990626 deletion of <=200bp C - downstream_gene_variant MELA-AU 19 1990626 1990626 deletion of <=200bp C - intron_variant MELA-AU 19 1990626 1990626 deletion of <=200bp C - upstream_gene_variant MELA-AU 19 1991532 1991532 single base substitution G A downstream_gene_variant MELA-AU 19 1991532 1991532 single base substitution G A intron_variant MELA-AU 19 1991532 1991532 single base substitution G A upstream_gene_variant MELA-AU 19 1992757 1992757 single base substitution G A downstream_gene_variant MELA-AU 19 1992757 1992757 single base substitution G A intron_variant MELA-AU 19 1992757 1992757 single base substitution G A upstream_gene_variant MELA-AU 19 1993531 1993531 single base substitution G A downstream_gene_variant MELA-AU 19 1993531 1993531 single base substitution G A intron_variant MELA-AU 19 1993531 1993531 single base substitution G A upstream_gene_variant MELA-AU 19 1993629 1993629 single base substitution G A downstream_gene_variant MELA-AU 19 1993629 1993629 single base substitution G A intron_variant MELA-AU 19 1993629 1993629 single base substitution G A upstream_gene_variant MELA-AU 19 1995235 1995235 single base substitution G A downstream_gene_variant MELA-AU 19 1995235 1995235 single base substitution G A intron_variant MELA-AU 19 1995235 1995235 single base substitution G A upstream_gene_variant MELA-AU 19 1995406 1995406 single base substitution G A downstream_gene_variant MELA-AU 19 1995406 1995406 single base substitution G A intron_variant MELA-AU 19 1995406 1995406 single base substitution G A upstream_gene_variant MELA-AU 19 1996354 1996354 single base substitution G A downstream_gene_variant MELA-AU 19 1996354 1996354 single base substitution G A intron_variant MELA-AU 19 1997105 1997105 single base substitution G A downstream_gene_variant MELA-AU 19 1997105 1997105 single base substitution G A intron_variant MELA-AU 19 1997166 1997166 single base substitution G A downstream_gene_variant MELA-AU 19 1997166 1997166 single base substitution G A intron_variant MELA-AU 19 1997459 1997459 single base substitution G A 3_prime_UTR_variant MELA-AU 19 1997459 1997459 single base substitution G A exon_variant MELA-AU 19 1997459 1997459 single base substitution G A synonymous_variant F137F 411C>T MELA-AU 19 1997459 1997459 single base substitution G A upstream_gene_variant MELA-AU 19 1997466 1997466 single base substitution G A intron_variant MELA-AU 19 1997466 1997466 single base substitution G A splice_region_variant MELA-AU 19 1997466 1997466 single base substitution G A upstream_gene_variant MELA-AU 19 1998001 1998001 single base substitution T A intron_variant MELA-AU 19 1998001 1998001 single base substitution T A upstream_gene_variant MELA-AU 19 1998276 1998276 single base substitution G A intron_variant MELA-AU 19 1998276 1998276 single base substitution G A upstream_gene_variant MELA-AU 19 1998289 1998289 single base substitution G A intron_variant MELA-AU 19 1998289 1998289 single base substitution G A upstream_gene_variant MELA-AU 19 1998537 1998537 single base substitution C A intron_variant MELA-AU 19 1998537 1998537 single base substitution C A upstream_gene_variant MELA-AU 19 1998771 1998771 single base substitution G A intron_variant MELA-AU 19 1998771 1998771 single base substitution G A upstream_gene_variant MELA-AU 19 2000342 2000342 single base substitution G A intron_variant MELA-AU 19 2000342 2000342 single base substitution G A upstream_gene_variant MELA-AU 19 2000893 2000893 single base substitution G A intron_variant MELA-AU 19 2000893 2000893 single base substitution G A upstream_gene_variant MELA-AU 19 2001853 2001853 single base substitution C T intron_variant MELA-AU 19 2001853 2001853 single base substitution C T upstream_gene_variant MELA-AU 19 2002568 2002568 single base substitution G A intron_variant MELA-AU 19 2003084 2003084 single base substitution G A intron_variant MELA-AU 19 2003208 2003208 single base substitution C A intron_variant MELA-AU 19 2003500 2003500 single base substitution G A intron_variant MELA-AU 19 2003697 2003697 single base substitution G A intron_variant MELA-AU 19 2003842 2003842 single base substitution C T intron_variant MELA-AU 19 2003848 2003849 multiple base substitution (>=2bp and <=200bp) GG TA intron_variant MELA-AU 19 2003863 2003863 single base substitution G A intron_variant MELA-AU 19 2004138 2004138 single base substitution A G intron_variant MELA-AU 19 2004286 2004286 single base substitution A G intron_variant MELA-AU 19 2005540 2005540 single base substitution G A intron_variant MELA-AU 19 2006344 2006344 single base substitution A T intron_variant MELA-AU 19 2006591 2006591 single base substitution A C intron_variant MELA-AU 19 2007938 2007938 single base substitution G A intron_variant MELA-AU 19 2009590 2009590 single base substitution G A intron_variant MELA-AU 19 2010077 2010077 single base substitution G A intron_variant MELA-AU 19 2010165 2010165 single base substitution G A intron_variant MELA-AU 19 2010355 2010356 multiple base substitution (>=2bp and <=200bp) CC AT intron_variant MELA-AU 19 2011781 2011781 single base substitution G A intron_variant MELA-AU 19 2012066 2012066 single base substitution G A intron_variant MELA-AU 19 2013716 2013716 single base substitution C T 3_prime_UTR_variant MELA-AU 19 2013716 2013716 single base substitution C T intron_variant MELA-AU 19 2013825 2013825 single base substitution G A 3_prime_UTR_variant MELA-AU 19 2013825 2013825 single base substitution G A intron_variant MELA-AU 19 2013995 2013995 single base substitution G A intron_variant MELA-AU 19 2014530 2014530 single base substitution G A intron_variant MELA-AU 19 2014606 2014606 single base substitution G A intron_variant MELA-AU 19 2016338 2016338 single base substitution C T intron_variant MELA-AU 19 2016338 2016338 single base substitution C T upstream_gene_variant MELA-AU 19 2016388 2016388 single base substitution C T intron_variant MELA-AU 19 2016388 2016388 single base substitution C T upstream_gene_variant MELA-AU 19 2016725 2016725 single base substitution C T intron_variant MELA-AU 19 2016725 2016725 single base substitution C T upstream_gene_variant MELA-AU 19 2017003 2017003 single base substitution C T intron_variant MELA-AU 19 2017003 2017003 single base substitution C T upstream_gene_variant MELA-AU 19 2017344 2017344 single base substitution G A intron_variant MELA-AU 19 2017344 2017344 single base substitution G A upstream_gene_variant MELA-AU 19 2017433 2017433 single base substitution T A intron_variant MELA-AU 19 2017433 2017433 single base substitution T A upstream_gene_variant MELA-AU 19 2017933 2017933 single base substitution C T intron_variant MELA-AU 19 2017933 2017933 single base substitution C T upstream_gene_variant MELA-AU 19 2018282 2018282 single base substitution G A intron_variant MELA-AU 19 2018282 2018282 single base substitution G A upstream_gene_variant MELA-AU 19 2018364 2018364 single base substitution C T intron_variant MELA-AU 19 2018364 2018364 single base substitution C T upstream_gene_variant MELA-AU 19 2018429 2018429 single base substitution G A intron_variant MELA-AU 19 2018429 2018429 single base substitution G A upstream_gene_variant MELA-AU 19 2018585 2018585 single base substitution C A intron_variant MELA-AU 19 2018585 2018585 single base substitution C A upstream_gene_variant MELA-AU 19 2018634 2018634 single base substitution C T intron_variant MELA-AU 19 2018634 2018634 single base substitution C T upstream_gene_variant MELA-AU 19 2018658 2018658 single base substitution G A intron_variant MELA-AU 19 2018658 2018658 single base substitution G A upstream_gene_variant MELA-AU 19 2019032 2019032 single base substitution C T intron_variant MELA-AU 19 2019032 2019032 single base substitution C T upstream_gene_variant MELA-AU 19 2019530 2019530 single base substitution G A intron_variant MELA-AU 19 2019530 2019530 single base substitution G A upstream_gene_variant MELA-AU 19 2019797 2019797 single base substitution C T intron_variant MELA-AU 19 2019797 2019797 single base substitution C T upstream_gene_variant MELA-AU 19 2020247 2020247 single base substitution C T intron_variant MELA-AU 19 2020247 2020247 single base substitution C T upstream_gene_variant MELA-AU 19 2020682 2020682 single base substitution C T intron_variant MELA-AU 19 2020682 2020682 single base substitution C T upstream_gene_variant MELA-AU 19 2020920 2020920 single base substitution C T intron_variant MELA-AU 19 2020932 2020932 single base substitution C T intron_variant MELA-AU 19 2021114 2021114 single base substitution G A intron_variant MELA-AU 19 2021374 2021374 single base substitution C T intron_variant MELA-AU 19 2021756 2021756 single base substitution C T intron_variant MELA-AU 19 2021902 2021902 single base substitution C T intron_variant MELA-AU 19 2022128 2022128 single base substitution G A intron_variant MELA-AU 19 2022168 2022168 single base substitution G A intron_variant MELA-AU 19 2022319 2022319 single base substitution G A intron_variant MELA-AU 19 2022550 2022550 single base substitution C T intron_variant MELA-AU 19 2022688 2022688 single base substitution C T intron_variant MELA-AU 19 2022720 2022720 single base substitution C T intron_variant MELA-AU 19 2023324 2023324 single base substitution C T intron_variant MELA-AU 19 2023464 2023464 single base substitution C T intron_variant MELA-AU 19 2023703 2023703 single base substitution G A intron_variant MELA-AU 19 2023956 2023956 single base substitution C T intron_variant MELA-AU 19 2024718 2024718 single base substitution G A intron_variant MELA-AU 19 2025138 2025138 single base substitution G A intron_variant MELA-AU 19 2025423 2025423 single base substitution C T intron_variant MELA-AU 19 2025957 2025957 single base substitution G A intron_variant MELA-AU 19 2026498 2026498 single base substitution G A intron_variant MELA-AU 19 2027720 2027720 single base substitution G A intron_variant MELA-AU 19 2028033 2028033 single base substitution G A intron_variant MELA-AU 19 2028084 2028084 single base substitution G A intron_variant MELA-AU 19 2028283 2028283 single base substitution G C intron_variant MELA-AU 19 2028388 2028388 single base substitution G A intron_variant MELA-AU 19 2028415 2028415 single base substitution G A intron_variant MELA-AU 19 2028678 2028678 single base substitution C T intron_variant MELA-AU 19 2029102 2029102 single base substitution C T intron_variant MELA-AU 19 2030194 2030194 single base substitution G A intron_variant MELA-AU 19 2030314 2030314 single base substitution G A intron_variant MELA-AU 19 2030706 2030706 single base substitution T C intron_variant MELA-AU 19 2030749 2030749 single base substitution C T intron_variant MELA-AU 19 2030944 2030944 single base substitution C T intron_variant MELA-AU 19 2030994 2030994 single base substitution G A intron_variant MELA-AU 19 2031301 2031301 single base substitution C T intron_variant MELA-AU 19 2031525 2031525 single base substitution G A intron_variant MELA-AU 19 2031983 2031983 single base substitution C T intron_variant MELA-AU 19 2032395 2032395 single base substitution C T intron_variant MELA-AU 19 2033359 2033359 single base substitution G A intron_variant MELA-AU 19 2033757 2033757 single base substitution G A intron_variant MELA-AU 19 2033815 2033815 single base substitution G A intron_variant MELA-AU 19 2034048 2034048 single base substitution C T intron_variant MELA-AU 19 2034348 2034348 single base substitution G A intron_variant MELA-AU 19 2035102 2035102 single base substitution C T upstream_gene_variant MELA-AU 19 2035172 2035172 single base substitution C T upstream_gene_variant MELA-AU 19 2035184 2035185 multiple base substitution (>=2bp and <=200bp) CC TT upstream_gene_variant MELA-AU 19 2035218 2035218 single base substitution C T upstream_gene_variant MELA-AU 19 2035298 2035298 single base substitution G C upstream_gene_variant MELA-AU 19 2035905 2035905 single base substitution C T upstream_gene_variant MELA-AU 19 2036353 2036353 single base substitution C T upstream_gene_variant MELA-AU 19 2036370 2036370 single base substitution G A upstream_gene_variant MELA-AU 19 2036904 2036904 single base substitution C T upstream_gene_variant MELA-AU 19 2038307 2038307 single base substitution G A upstream_gene_variant MELA-AU 19 2038374 2038374 single base substitution A G upstream_gene_variant MELA-AU 19 2038522 2038522 single base substitution G A upstream_gene_variant MELA-AU 19 2038722 2038722 single base substitution G A upstream_gene_variant ORCA-IN 19 2000223 2000223 single base substitution C T intron_variant ORCA-IN 19 2000223 2000223 single base substitution C T upstream_gene_variant ORCA-IN 19 2019154 2019154 single base substitution G A intron_variant ORCA-IN 19 2019154 2019154 single base substitution G A upstream_gene_variant ORCA-IN 19 2031502 2031502 single base substitution G C intron_variant OV-AU 19 1987929 1987929 single base substitution C G downstream_gene_variant OV-AU 19 1987929 1987929 single base substitution C G exon_variant OV-AU 19 1987929 1987929 single base substitution C G intron_variant OV-AU 19 1998109 1998109 single base substitution C T intron_variant OV-AU 19 1998109 1998109 single base substitution C T upstream_gene_variant OV-AU 19 2004310 2004310 single base substitution T A intron_variant OV-AU 19 2004943 2004943 single base substitution C T intron_variant OV-AU 19 2006682 2006682 single base substitution T C intron_variant OV-AU 19 2007312 2007312 single base substitution G C intron_variant OV-AU 19 2008387 2008387 single base substitution C T intron_variant OV-AU 19 2012181 2012181 single base substitution T C intron_variant OV-AU 19 2013613 2013613 single base substitution G A 3_prime_UTR_variant OV-AU 19 2013613 2013613 single base substitution G A intron_variant OV-AU 19 2021197 2021197 single base substitution G C intron_variant OV-AU 19 2032193 2032193 single base substitution A G intron_variant OV-AU 19 2033625 2033625 single base substitution T A intron_variant OV-AU 19 2035263 2035263 single base substitution T A upstream_gene_variant OV-AU 19 2038248 2038248 single base substitution T A upstream_gene_variant OV-US 19 1997416 1997416 single base substitution C T 3_prime_UTR_variant OV-US 19 1997416 1997416 single base substitution C T exon_variant OV-US 19 1997416 1997416 single base substitution C T missense_variant G152R 454G>A OV-US 19 1997416 1997416 single base substitution C T missense_variant G3R 7G>A PACA-AU 19 1982509 1982509 single base substitution G T downstream_gene_variant PACA-AU 19 1984545 1984545 single base substitution C G downstream_gene_variant PACA-AU 19 1985586 1985586 single base substitution G A 3_prime_UTR_variant PACA-AU 19 1985586 1985586 single base substitution G A downstream_gene_variant PACA-AU 19 1985586 1985586 single base substitution G A exon_variant PACA-AU 19 1986962 1986962 deletion of <=200bp T - downstream_gene_variant PACA-AU 19 1986962 1986962 deletion of <=200bp T - exon_variant PACA-AU 19 1986962 1986962 deletion of <=200bp T - frameshift_variant D428 PACA-AU 19 1991925 1991926 multiple base substitution (>=2bp and <=200bp) TC CT downstream_gene_variant PACA-AU 19 1991925 1991926 multiple base substitution (>=2bp and <=200bp) TC CT intron_variant PACA-AU 19 1991925 1991926 multiple base substitution (>=2bp and <=200bp) TC CT missense_variant E123R 367GA>AG PACA-AU 19 1991925 1991926 multiple base substitution (>=2bp and <=200bp) TC CT upstream_gene_variant PACA-AU 19 1997268 1997268 single base substitution C T downstream_gene_variant PACA-AU 19 1997268 1997268 single base substitution C T intron_variant PACA-AU 19 1997497 1997497 single base substitution G A intron_variant PACA-AU 19 1997497 1997497 single base substitution G A upstream_gene_variant PACA-AU 19 2003150 2003150 single base substitution G A intron_variant PACA-AU 19 2003302 2003302 single base substitution C A intron_variant PACA-AU 19 2011277 2011277 single base substitution A C intron_variant PACA-AU 19 2011473 2011473 single base substitution C A intron_variant PACA-AU 19 2011474 2011474 single base substitution A G intron_variant PACA-AU 19 2012738 2012738 single base substitution A C intron_variant PACA-AU 19 2013153 2013153 single base substitution C T intron_variant PACA-AU 19 2016676 2016676 single base substitution C T intron_variant PACA-AU 19 2016676 2016676 single base substitution C T upstream_gene_variant PACA-AU 19 2027154 2027154 single base substitution C T intron_variant PACA-AU 19 2027407 2027407 single base substitution C T intron_variant PACA-AU 19 2028039 2028039 single base substitution C T intron_variant PACA-AU 19 2030976 2030976 single base substitution C T intron_variant PACA-AU 19 2032853 2032853 single base substitution G T intron_variant PACA-AU 19 2037842 2037842 single base substitution A C upstream_gene_variant PACA-AU 19 2038221 2038221 single base substitution G T upstream_gene_variant PACA-CA 19 1980638 1980638 single base substitution C T downstream_gene_variant PACA-CA 19 1986408 1986408 deletion of <=200bp G - 3_prime_UTR_variant PACA-CA 19 1986408 1986408 deletion of <=200bp G - downstream_gene_variant PACA-CA 19 1986408 1986408 deletion of <=200bp G - exon_variant PACA-CA 19 1992515 1992515 single base substitution A T downstream_gene_variant PACA-CA 19 1992515 1992515 single base substitution A T intron_variant PACA-CA 19 1992515 1992515 single base substitution A T upstream_gene_variant PACA-CA 19 1998436 1998436 single base substitution G A intron_variant PACA-CA 19 1998436 1998436 single base substitution G A upstream_gene_variant PACA-CA 19 2003095 2003095 single base substitution C T intron_variant PACA-CA 19 2003839 2003839 single base substitution A G intron_variant PACA-CA 19 2009220 2009220 single base substitution C T intron_variant PACA-CA 19 2010006 2010006 single base substitution C G intron_variant PACA-CA 19 2017976 2017976 single base substitution C T intron_variant PACA-CA 19 2017976 2017976 single base substitution C T upstream_gene_variant PACA-CA 19 2020086 2020086 single base substitution C T intron_variant PACA-CA 19 2020086 2020086 single base substitution C T upstream_gene_variant PACA-CA 19 2026559 2026559 single base substitution G T intron_variant PACA-CA 19 2028362 2028362 single base substitution G A intron_variant PACA-CA 19 2028756 2028756 single base substitution G C exon_variant PACA-CA 19 2028756 2028756 single base substitution G C intron_variant PACA-CA 19 2031913 2031913 single base substitution G T intron_variant PACA-CA 19 2032107 2032107 single base substitution A C intron_variant PACA-CA 19 2034379 2034379 single base substitution G A intron_variant PACA-CA 19 2035331 2035331 single base substitution T C upstream_gene_variant PACA-CA 19 2035895 2035895 single base substitution C T upstream_gene_variant PACA-CA 19 2037842 2037842 single base substitution A C upstream_gene_variant PACA-CA 19 2039272 2039272 single base substitution G A upstream_gene_variant PACA-CA 19 2039625 2039625 single base substitution C T upstream_gene_variant PAEN-AU 19 1985741 1985741 single base substitution T G 3_prime_UTR_variant PAEN-AU 19 1985741 1985741 single base substitution T G downstream_gene_variant PAEN-AU 19 1985741 1985741 single base substitution T G exon_variant PAEN-AU 19 1999580 1999580 single base substitution G A intron_variant PAEN-AU 19 1999580 1999580 single base substitution G A upstream_gene_variant PAEN-AU 19 2013221 2013221 single base substitution A C intron_variant PAEN-AU 19 2014563 2014563 single base substitution T G intron_variant PAEN-IT 19 2023273 2023273 single base substitution G T intron_variant PBCA-DE 19 1983263 1983263 single base substitution C T downstream_gene_variant PBCA-DE 19 1988147 1988147 single base substitution C T downstream_gene_variant PBCA-DE 19 1988147 1988147 single base substitution C T exon_variant PBCA-DE 19 1988147 1988147 single base substitution C T intron_variant PBCA-DE 19 1994068 1994068 insertion of <=200bp - CA downstream_gene_variant PBCA-DE 19 1994068 1994068 insertion of <=200bp - CA intron_variant PBCA-DE 19 1994068 1994068 insertion of <=200bp - CA upstream_gene_variant PBCA-DE 19 1995788 1995788 single base substitution A G downstream_gene_variant PBCA-DE 19 1995788 1995788 single base substitution A G intron_variant PBCA-DE 19 1995788 1995788 single base substitution A G upstream_gene_variant PBCA-DE 19 2001080 2001080 single base substitution C T intron_variant PBCA-DE 19 2001080 2001080 single base substitution C T upstream_gene_variant PBCA-DE 19 2004815 2004815 deletion of <=200bp A - intron_variant PBCA-DE 19 2016826 2016826 single base substitution C G intron_variant PBCA-DE 19 2016826 2016826 single base substitution C G upstream_gene_variant PBCA-DE 19 2018076 2018076 deletion of <=200bp C - intron_variant PBCA-DE 19 2018076 2018076 deletion of <=200bp C - upstream_gene_variant PBCA-DE 19 2021735 2021735 single base substitution G A intron_variant PBCA-DE 19 2027496 2027497 deletion of <=200bp AG - intron_variant PBCA-DE 19 2031474 2031475 deletion of <=200bp CA - intron_variant PBCA-DE 19 2032065 2032065 single base substitution T A intron_variant PBCA-DE 19 2036470 2036470 single base substitution G T upstream_gene_variant PBCA-DE 19 2037146 2037147 deletion of <=200bp CA - upstream_gene_variant PBCA-DE 19 2037842 2037842 single base substitution A C upstream_gene_variant PRAD-CA 19 1991926 1991926 single base substitution C T downstream_gene_variant PRAD-CA 19 1991926 1991926 single base substitution C T intron_variant PRAD-CA 19 1991926 1991926 single base substitution C T missense_variant E123K 367G>A PRAD-CA 19 1991926 1991926 single base substitution C T upstream_gene_variant PRAD-CA 19 1993257 1993257 single base substitution G A downstream_gene_variant PRAD-CA 19 1993257 1993257 single base substitution G A intron_variant PRAD-CA 19 1993257 1993257 single base substitution G A upstream_gene_variant PRAD-CA 19 1996489 1996489 single base substitution G T downstream_gene_variant PRAD-CA 19 1996489 1996489 single base substitution G T intron_variant PRAD-CA 19 1996491 1996491 single base substitution T C downstream_gene_variant PRAD-CA 19 1996491 1996491 single base substitution T C intron_variant PRAD-CA 19 2011412 2011412 single base substitution A G intron_variant PRAD-CA 19 2017038 2017038 single base substitution T C intron_variant PRAD-CA 19 2017038 2017038 single base substitution T C splice_region_variant PRAD-CA 19 2017038 2017038 single base substitution T C upstream_gene_variant PRAD-CA 19 2022456 2022456 single base substitution T C intron_variant PRAD-CA 19 2033965 2033965 single base substitution C T intron_variant PRAD-UK 19 1984318 1984318 single base substitution C T downstream_gene_variant PRAD-UK 19 1987900 1987900 single base substitution C T downstream_gene_variant PRAD-UK 19 1987900 1987900 single base substitution C T exon_variant PRAD-UK 19 1987900 1987900 single base substitution C T intron_variant PRAD-UK 19 2012300 2012300 single base substitution C T intron_variant PRAD-UK 19 2019127 2019127 single base substitution G A intron_variant PRAD-UK 19 2019127 2019127 single base substitution G A upstream_gene_variant PRAD-UK 19 2019927 2019927 single base substitution C A intron_variant PRAD-UK 19 2019927 2019927 single base substitution C A upstream_gene_variant PRAD-UK 19 2024095 2024095 single base substitution G T intron_variant PRAD-UK 19 2025136 2025136 single base substitution A C intron_variant PRAD-UK 19 2026200 2026200 single base substitution C T intron_variant PRAD-UK 19 2031176 2031176 single base substitution G T intron_variant PRAD-US 19 1986928 1986928 single base substitution G A downstream_gene_variant PRAD-US 19 1986928 1986928 single base substitution G A exon_variant PRAD-US 19 1986928 1986928 single base substitution G A synonymous_variant G439G 1317C>T READ-US 19 1987687 1987687 single base substitution G A downstream_gene_variant READ-US 19 1987687 1987687 single base substitution G A exon_variant READ-US 19 1987687 1987687 single base substitution G A synonymous_variant P242P 726C>T READ-US 19 1987687 1987687 single base substitution G A synonymous_variant P331P 993C>T RECA-EU 19 1988359 1988359 single base substitution C T downstream_gene_variant RECA-EU 19 1988359 1988359 single base substitution C T exon_variant RECA-EU 19 1988359 1988359 single base substitution C T intron_variant RECA-EU 19 2002893 2002893 single base substitution A G intron_variant RECA-EU 19 2004029 2004029 single base substitution T C intron_variant RECA-EU 19 2006505 2006505 single base substitution C A intron_variant RECA-EU 19 2024567 2024567 single base substitution G A intron_variant SKCA-BR 19 1980497 1980497 single base substitution A C downstream_gene_variant SKCA-BR 19 1983001 1983001 single base substitution T G downstream_gene_variant SKCA-BR 19 1984619 1984619 single base substitution A C downstream_gene_variant SKCA-BR 19 1989812 1989812 single base substitution A G downstream_gene_variant SKCA-BR 19 1989812 1989812 single base substitution A G exon_variant SKCA-BR 19 1989812 1989812 single base substitution A G intron_variant SKCA-BR 19 1989812 1989812 single base substitution A G upstream_gene_variant SKCA-BR 19 1989921 1989921 single base substitution G A downstream_gene_variant SKCA-BR 19 1989921 1989921 single base substitution G A exon_variant SKCA-BR 19 1989921 1989921 single base substitution G A intron_variant SKCA-BR 19 1989921 1989921 single base substitution G A upstream_gene_variant SKCA-BR 19 1989936 1989936 single base substitution G A downstream_gene_variant SKCA-BR 19 1989936 1989936 single base substitution G A exon_variant SKCA-BR 19 1989936 1989936 single base substitution G A intron_variant SKCA-BR 19 1989936 1989936 single base substitution G A upstream_gene_variant SKCA-BR 19 1990654 1990654 single base substitution T C downstream_gene_variant SKCA-BR 19 1990654 1990654 single base substitution T C intron_variant SKCA-BR 19 1990654 1990654 single base substitution T C upstream_gene_variant SKCA-BR 19 1995146 1995146 single base substitution T C downstream_gene_variant SKCA-BR 19 1995146 1995146 single base substitution T C intron_variant SKCA-BR 19 1995146 1995146 single base substitution T C upstream_gene_variant SKCA-BR 19 1995639 1995639 insertion of <=200bp - AT downstream_gene_variant SKCA-BR 19 1995639 1995639 insertion of <=200bp - AT intron_variant SKCA-BR 19 1995639 1995639 insertion of <=200bp - AT upstream_gene_variant SKCA-BR 19 1998228 1998228 single base substitution G T intron_variant SKCA-BR 19 1998228 1998228 single base substitution G T upstream_gene_variant SKCA-BR 19 1998814 1998814 single base substitution G A intron_variant SKCA-BR 19 1998814 1998814 single base substitution G A upstream_gene_variant SKCA-BR 19 1999361 1999361 single base substitution T G intron_variant SKCA-BR 19 1999361 1999361 single base substitution T G upstream_gene_variant SKCA-BR 19 2000780 2000780 single base substitution G A intron_variant SKCA-BR 19 2000780 2000780 single base substitution G A upstream_gene_variant SKCA-BR 19 2002372 2002372 single base substitution G A intron_variant SKCA-BR 19 2002372 2002372 single base substitution G A upstream_gene_variant SKCA-BR 19 2005780 2005781 deletion of <=200bp CA - intron_variant SKCA-BR 19 2006557 2006557 single base substitution G A intron_variant SKCA-BR 19 2006991 2006991 single base substitution G A intron_variant SKCA-BR 19 2007706 2007706 single base substitution T C intron_variant SKCA-BR 19 2008456 2008456 single base substitution C A intron_variant SKCA-BR 19 2008588 2008588 insertion of <=200bp - CT intron_variant SKCA-BR 19 2012382 2012382 single base substitution C T intron_variant SKCA-BR 19 2015283 2015283 single base substitution T G intron_variant SKCA-BR 19 2016875 2016875 single base substitution G A intron_variant SKCA-BR 19 2016875 2016875 single base substitution G A upstream_gene_variant SKCA-BR 19 2017815 2017816 deletion of <=200bp TA - intron_variant SKCA-BR 19 2017815 2017816 deletion of <=200bp TA - upstream_gene_variant SKCA-BR 19 2017958 2017958 single base substitution G A intron_variant SKCA-BR 19 2017958 2017958 single base substitution G A upstream_gene_variant SKCA-BR 19 2018695 2018695 single base substitution C T intron_variant SKCA-BR 19 2018695 2018695 single base substitution C T upstream_gene_variant SKCA-BR 19 2019159 2019159 single base substitution G A intron_variant SKCA-BR 19 2019159 2019159 single base substitution G A upstream_gene_variant SKCA-BR 19 2019647 2019647 insertion of <=200bp - TTTGC intron_variant SKCA-BR 19 2019647 2019647 insertion of <=200bp - TTTGC upstream_gene_variant SKCA-BR 19 2020866 2020866 single base substitution G A intron_variant SKCA-BR 19 2022840 2022840 single base substitution C T intron_variant SKCA-BR 19 2022856 2022856 single base substitution C T intron_variant SKCA-BR 19 2024862 2024862 single base substitution A G intron_variant SKCA-BR 19 2025820 2025820 single base substitution C T intron_variant SKCA-BR 19 2026105 2026105 insertion of <=200bp - CT intron_variant SKCA-BR 19 2030792 2030792 single base substitution A C intron_variant SKCA-BR 19 2032310 2032310 single base substitution C T intron_variant SKCA-BR 19 2034210 2034210 single base substitution T G intron_variant SKCA-BR 19 2034991 2034991 single base substitution C T upstream_gene_variant SKCA-BR 19 2035945 2035945 single base substitution C T upstream_gene_variant SKCA-BR 19 2039273 2039273 single base substitution G A upstream_gene_variant SKCA-BR 19 2039427 2039427 single base substitution G A upstream_gene_variant SKCM-US 19 1986899 1986899 single base substitution A C downstream_gene_variant SKCM-US 19 1986899 1986899 single base substitution A C exon_variant SKCM-US 19 1986899 1986899 single base substitution A C missense_variant F449C 1346T>G SKCM-US 19 1997393 1997393 single base substitution C T 3_prime_UTR_variant SKCM-US 19 1997393 1997393 single base substitution C T exon_variant SKCM-US 19 1997393 1997393 single base substitution C T synonymous_variant T10T 30G>A SKCM-US 19 1997393 1997393 single base substitution C T synonymous_variant T159T 477G>A STAD-US 19 1986508 1986508 deletion of <=200bp G - downstream_gene_variant STAD-US 19 1986508 1986508 deletion of <=200bp G - exon_variant STAD-US 19 1986508 1986508 deletion of <=200bp G - frameshift_variant P519 STAD-US 19 1990129 1990129 single base substitution G A 3_prime_UTR_variant STAD-US 19 1990129 1990129 single base substitution G A downstream_gene_variant STAD-US 19 1990129 1990129 single base substitution G A exon_variant STAD-US 19 1990129 1990129 single base substitution G A missense_variant R199C 595C>T STAD-US 19 1990129 1990129 single base substitution G A missense_variant R288C 862C>T STAD-US 19 1990129 1990129 single base substitution G A upstream_gene_variant STAD-US 19 1993114 1993114 single base substitution C A 3_prime_UTR_variant STAD-US 19 1993114 1993114 single base substitution C A downstream_gene_variant STAD-US 19 1993114 1993114 single base substitution C A exon_variant STAD-US 19 1993114 1993114 single base substitution C A missense_variant A197S 589G>T STAD-US 19 1993114 1993114 single base substitution C A missense_variant A48S 142G>T STAD-US 19 1993114 1993114 single base substitution C A upstream_gene_variant STAD-US 19 1993130 1993130 single base substitution C T 3_prime_UTR_variant STAD-US 19 1993130 1993130 single base substitution C T downstream_gene_variant STAD-US 19 1993130 1993130 single base substitution C T exon_variant STAD-US 19 1993130 1993130 single base substitution C T missense_variant M191I 573G>A STAD-US 19 1993130 1993130 single base substitution C T missense_variant M42I 126G>A STAD-US 19 1993130 1993130 single base substitution C T upstream_gene_variant STAD-US 19 2039737 2039737 single base substitution C T upstream_gene_variant THCA-US 19 1987243 1987243 single base substitution G A downstream_gene_variant THCA-US 19 1987243 1987243 single base substitution G A exon_variant THCA-US 19 1987243 1987243 single base substitution G A synonymous_variant V308V 924C>T THCA-US 19 1987243 1987243 single base substitution G A synonymous_variant V397V 1191C>T UCEC-US 19 1986553 1986553 single base substitution C T downstream_gene_variant UCEC-US 19 1986553 1986553 single base substitution C T exon_variant UCEC-US 19 1986553 1986553 single base substitution C T synonymous_variant A504A 1512G>A UCEC-US 19 1987252 1987252 single base substitution C T downstream_gene_variant UCEC-US 19 1987252 1987252 single base substitution C T exon_variant UCEC-US 19 1987252 1987252 single base substitution C T splice_region_variant UCEC-US 19 1987554 1987554 single base substitution G A downstream_gene_variant UCEC-US 19 1987554 1987554 single base substitution G A exon_variant UCEC-US 19 1987554 1987554 single base substitution G A missense_variant R287C 859C>T UCEC-US 19 1987554 1987554 single base substitution G A missense_variant R376C 1126C>T UCEC-US 19 1990752 1990752 single base substitution C T 3_prime_UTR_variant UCEC-US 19 1990752 1990752 single base substitution C T downstream_gene_variant UCEC-US 19 1990752 1990752 single base substitution C T exon_variant UCEC-US 19 1990752 1990752 single base substitution C T missense_variant A163T 487G>A UCEC-US 19 1990752 1990752 single base substitution C T missense_variant A252T 754G>A UCEC-US 19 1990752 1990752 single base substitution C T upstream_gene_variant UCEC-US 19 1990753 1990753 single base substitution G A 3_prime_UTR_variant UCEC-US 19 1990753 1990753 single base substitution G A downstream_gene_variant UCEC-US 19 1990753 1990753 single base substitution G A exon_variant UCEC-US 19 1990753 1990753 single base substitution G A synonymous_variant D162D 486C>T UCEC-US 19 1990753 1990753 single base substitution G A synonymous_variant D251D 753C>T UCEC-US 19 1990753 1990753 single base substitution G A upstream_gene_variant UCEC-US 19 1990818 1990818 single base substitution G A 3_prime_UTR_variant UCEC-US 19 1990818 1990818 single base substitution G A downstream_gene_variant UCEC-US 19 1990818 1990818 single base substitution G A exon_variant UCEC-US 19 1990818 1990818 single base substitution G A stop_gained R141* 421C>T UCEC-US 19 1990818 1990818 single base substitution G A stop_gained R230* 688C>T UCEC-US 19 1990818 1990818 single base substitution G A upstream_gene_variant UCEC-US 19 1997427 1997427 single base substitution G A 3_prime_UTR_variant UCEC-US 19 1997427 1997427 single base substitution G A exon_variant UCEC-US 19 1997427 1997427 single base substitution G A missense_variant A148V 443C>T UCEC-US 19 1997427 1997427 single base substitution G A upstream_gene_variant UCEC-US 19 2037757 2037757 single base substitution G A upstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand 1960034 COSM1644257 c.1067G>A p.R356Q Substitution - Missense 19:1987614-1987614 - PT46 COSM5929852 c.1348C>T p.R450C Substitution - Missense 19:1986898-1986898 - CHC2127T COSM4952891 c.686C>A p.A229E Substitution - Missense 19:1990821-1990821 - MOLT-4 COSM1680480 c.946C>A p.L316I Substitution - Missense 19:1990046-1990046 - Pat_30_A COSM5855169 c.751G>A p.D251N Substitution - Missense 19:1990756-1990756 - TCGA-AP-A0LM-01 COSM993437 c.688C>T p.R230* Substitution - Nonsense 19:1990819-1990819 - T3306 COSM4666338 c.1117A>T p.S373C Substitution - Missense 19:1987564-1987564 - 2492700 COSM5715406 c.1088C>T p.P363L Substitution - Missense 19:1987593-1987593 - TCGA-A6-6781-01 COSM1391816 c.1127G>A p.R376H Substitution - Missense 19:1987554-1987554 - TCGA-EI-6882-01 COSM3422569 c.993C>T p.P331P Substitution - coding silent 19:1987688-1987688 - TCGA-EP-A26S-01 COSM4913576 c.445A>G p.M149V Substitution - Missense 19:1997426-1997426 - I2L-P19Ta-Tumor-Organoid COSM5364950 c.1513G>A p.A505T Substitution - Missense 19:1986553-1986553 - TCGA-DU-A5TY-01 COSM3970859 c.1141G>A p.E381K Substitution - Missense 19:1987540-1987540 - 2492703 COSM5715406 c.1088C>T p.P363L Substitution - Missense 19:1987593-1987593 - C008 COSM5522209 c.966G>A p.M322I Substitution - Missense 19:1990026-1990026 - YUPAT COSM1711586 c.973G>A p.E325K Substitution - Missense 19:1990019-1990019 - TCGA-P4-A5ED-01 COSM3989857 c.1287C>T p.S429S Substitution - coding silent 19:1986959-1986959 - CHC2127T COSM4952891 c.686C>A p.A229E Substitution - Missense 19:1990821-1990821 - T2458 COSM4666337 c.1478C>T p.T493M Substitution - Missense 19:1986588-1986588 - TCGA-BR-8363-01 COSM4076038 c.862C>T p.R288C Substitution - Missense 19:1990130-1990130 - BD236T COSM5519569 c.575C>T p.T192I Substitution - Missense 19:1993129-1993129 - ESO-1145 COSM1246294 c.1308C>T p.N436N Substitution - coding silent 19:1986938-1986938 - TCGA-D1-A15X-01 COSM993436 c.753C>T p.D251D Substitution - coding silent 19:1990754-1990754 - RKO COSM4648237 c.1040T>C p.L347P Substitution - Missense 19:1987641-1987641 - NB-0462 COSM1283691 c.1109delA p.K370fs*51 Deletion - Frameshift 19:1987572-1987572 - ESCC-038T COSM3937955 c.1369G>A p.V457M Substitution - Missense 19:1986877-1986877 - TCGA-AP-A0LD-01 COSM993426 c.1206C>T p.F402F Substitution - coding silent 19:1987229-1987229 - TCGA-B5-A11E-01 COSM993435 c.754G>A p.A252T Substitution - Missense 19:1990753-1990753 - TCGA-AM-5821-01 COSM3756528 c.507T>C p.A169A Substitution - coding silent 19:1997364-1997364 - 12T COSM108542 c.1077C>T p.F359F Substitution - coding silent 19:1987604-1987604 - HCC080T COSM5810532 c.1339A>T p.S447C Substitution - Missense 19:1986907-1986907 - ESO-536 COSM1246296 c.1410G>A p.T470T Substitution - coding silent 19:1986836-1986836 - TCGA-CZ-4854-01 COSM3101829 c.1563C>T p.V521V Substitution - coding silent 19:1986503-1986503 - 587284 COSM993435 c.754G>A p.A252T Substitution - Missense 19:1990753-1990753 - sysucc-1317T COSM4076038 c.862C>T p.R288C Substitution - Missense 19:1990130-1990130 - TCGA-13-1506-01 COSM73868 c.454G>A p.G152R Substitution - Missense 19:1997417-1997417 - TCGA-B5-A0JR-01 COSM993424 c.1429C>T p.H477Y Substitution - Missense 19:1986637-1986637 - ESO-159 COSM1246295 c.1031G>T p.S344I Substitution - Missense 19:1987650-1987650 - TCGA-DK-A3IU-01 COSM3796852 c.552G>C p.Q184H Substitution - Missense 19:1993152-1993152 - QC2-34-T2 COSM5654994 c.785A>T p.D262V Substitution - Missense 19:1990722-1990722 - TCGA-D9-A149-06 COSM369164 c.477G>A p.T159T Substitution - coding silent 19:1997394-1997394 - C91 COSM4444660 c.1313C>T p.T438M Substitution - Missense 19:1986933-1986933 - 35M COSM5580364 c.510C>T p.A170A Substitution - coding silent 19:1997361-1997361 - CRC-02T COSM5454703 c.1102C>T p.R368C Substitution - Missense 19:1987579-1987579 - Pat_45_A COSM5855170 c.430G>A p.A144T Substitution - Missense 19:1997441-1997441 - SJHGG034_D COSM4970277 c.1239C>T p.H413H Substitution - coding silent 19:1987196-1987196 - T2225 COSM4666341 c.495C>T p.D165D Substitution - coding silent 19:1997376-1997376 - 201 COSM3720995 c.1447C>T p.L483L Substitution - coding silent 19:1986619-1986619 - T31 COSM3756528 c.507T>C p.A169A Substitution - coding silent 19:1997364-1997364 - GC8_T COSM148453 c.685-4C>T p.? Unknown 19:1990826-1990826 - TCGA-AP-A0LE-01 COSM993427 c.1182G>A p.R394R Substitution - coding silent 19:1987253-1987253 - TCGA-G4-6628-01 COSM1391817 c.1044C>A p.H348Q Substitution - Missense 19:1987637-1987637 - SNUH_G16_S1 COSM3756528 c.507T>C p.A169A Substitution - coding silent 19:1997364-1997364 - PD11752a COSM5802393 c.645_647delGAA p.K215delK Deletion - In frame 19:1993057-1993059 - MO_1015 COSM5558991 c.674T>A p.L225Q Substitution - Missense 19:1993030-1993030 - TCGA-BS-A0UV-01 COSM993428 c.1126C>T p.R376C Substitution - Missense 19:1987555-1987555 - SH-85592 COSM5018110 c.1207G>T p.V403L Substitution - Missense 19:1987228-1987228 - TCGA-AP-A059-01 COSM993423 c.1512G>A p.A504A Substitution - coding silent 19:1986554-1986554 - TCGA-BJ-A45J-01 COSM3371232 c.1191C>T p.V397V Substitution - coding silent 19:1987244-1987244 - TCGA-D1-A0ZS-01 COSM993438 c.443C>T p.A148V Substitution - Missense 19:1997428-1997428 - I2L-P19Ta-Tumor-Biopsy COSM5364950 c.1513G>A p.A505T Substitution - Missense 19:1986553-1986553 - T3190 COSM1246294 c.1308C>T p.N436N Substitution - coding silent 19:1986938-1986938 - ZZUFHECRKL-G060T COSM3756528 c.507T>C p.A169A Substitution - coding silent 19:1997364-1997364 - sysucc-1370T COSM3101836 c.1416+4C>T p.? Unknown 19:1986826-1986826 - TCGA-BP-4967-01 COSM474409 c.570G>A p.V190V Substitution - coding silent 19:1993134-1993134 - T578 COSM4666340 c.735C>T p.I245I Substitution - coding silent 19:1990772-1990772 - TCGA-BQ-5877-01 COSM3989856 c.1368G>C p.P456P Substitution - coding silent 19:1986878-1986878 - TCGA-D1-A177-01 COSM993425 c.1212G>T p.V404V Substitution - coding silent 19:1987223-1987223 - TCGA-D3-A3MV-06 COSM3531168 c.1346T>G p.F449C Substitution - Missense 19:1986900-1986900 - TCGA-G4-6317-01 COSM1391816 c.1127G>A p.R376H Substitution - Missense 19:1987554-1987554 - PD4255a COSM5774494 c.1349G>A p.R450H Substitution - Missense 19:1986897-1986897 - ACA34 COSM5961651 c.653G>C p.R218P Substitution - Missense 19:1993051-1993051 - TCGA-CK-5916-01 COSM3692555 c.429C>T p.S143S Substitution - coding silent 19:1997442-1997442 - TCGA-EJ-A46F-01 COSM3783211 c.1317C>T p.G439G Substitution - coding silent 19:1986929-1986929 - LUAD-NYU1096 COSM369164 c.477G>A p.T159T Substitution - coding silent 19:1997394-1997394 - MOLT-4 COSM1680479 c.1436G>A p.G479D Substitution - Missense 19:1986630-1986630 - 2492702 COSM5715406 c.1088C>T p.P363L Substitution - Missense 19:1987593-1987593 - TCGA-HU-A4GX-01 COSM4076045 c.589G>T p.A197S Substitution - Missense 19:1993115-1993115 - TCGA-CM-5861-01 COSM1391818 c.765G>A p.A255A Substitution - coding silent 19:1990742-1990742 - TCGA-HU-A4GQ-01 COSM4076038 c.862C>T p.R288C Substitution - Missense 19:1990130-1990130 - T3092 COSM4666339 c.1085G>A p.R362Q Substitution - Missense 19:1987596-1987596 - 2492701 COSM5715406 c.1088C>T p.P363L Substitution - Missense 19:1987593-1987593 - YUKAT COSM5389187 c.1444G>A p.G482S Substitution - Missense 19:1986622-1986622 - 46M COSM5587307 c.527+1G>T p.? Unknown 19:1997343-1997343 - TCGA-BR-8487-01 COSM4076046 c.573G>A p.M191I Substitution - Missense 19:1993131-1993131 - pfg068T COSM4748611 c.994G>A p.A332T Substitution - Missense 19:1987687-1987687 - 19 COSM5747958 c.467C>T p.T156I Substitution - Missense 19:1997404-1997404 - GC_297_T-GC_297_N COSM4772720 c.1435G>A p.G479S Substitution - Missense 19:1986631-1986631 - YUROC COSM5389188 c.1282G>A p.D428N Substitution - Missense 19:1986964-1986964 - ESCC_29 COSM5627493 c.851A>T p.N284I Substitution - Missense 19:1990141-1990141 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.465543 19p13.3 608531 1517406|dbSNP|BC000564|C/T|non-coding||1807|Validated; 1517406|dbSNP|BC008035|C/T|non-coding||1801|Validated

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C Missense p.F449C c.1346T>G 19 1986899 CM A G Missense p.L483P c.1448T>C 19 1986617 STAD C G Missense p.Q184H c.552G>C 19 1993151 BLCA C T Missense p.D475N c.1423G>A 19 1986642 LUAD C T Missense p.G152R c.454G>A 19 1997416 OV C T Missense p.G439S c.1315G>A 19 1986930 CM C T Synonymous p.E341E c.1023G>A 19 1987657 CM C T Synonymous p.K199K c.597G>A 19 1993106 HNSC C T Synonymous p.R394R c.1182G>A 19 1987252 UCEC C T Synonymous p.T193T c.579G>A 19 1993124 STAD C T Synonymous p.T470T c.1410G>A 19 1986835 ESCA C T Synonymous p.V190V c.570G>A 19 1993133 RCCC G A Missense p.A148V c.443C>T 19 1997427 UCEC G A Synonymous p.G439G c.1317C>T 19 1986928 PRAD G A Synonymous p.N436N c.1308C>T 19 1986937 ESCA G A Synonymous p.V521V c.1563C>T 19 1986502 RCCC G C Nonsense p.Y179* c.537C>G 19 1993166 HNSC G T IntronicSNV . c.408-7099C>A 19 2004561 PIA G T Synonymous p.P168P c.504C>A 19 1997366 LUAD T - Frameshift p.K370Rfs*51 c.1109delA 19 1987571 NB - TG 3-UTRInsertion . c.1575+129_1575+130insCA 19 1986360 ESCA