PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBE2D1 TRIM45 21143188 biogrid exp G G G G G GP G G G G G G GP GP G G GP G G G GP G G GP G G G G G UBE2E1 TRIM45 21143188 biogrid exp G GP G G G GP G G G G G G G GP G G GP G G G GP G G GP G G G G G UBE2D2 TRIM45 21143188 biogrid exp G G G G G GP G G G G G G GP GP G G GP G G G GP G G GP G G G G G TRIM45 TRIM45 24681954 biogrid exp G GP G G G GP G GP G G G G GP GP G G GP G G G GP G G GP G G G G G UBE2E3 TRIM45 21143188 biogrid exp G GP G G G GP G G G G G G G GP G G GP G G G GP G G GP G G G G G UBE2D3 TRIM45 21143188 biogrid exp G G G G G GP G G G G G G GP GP G G GP G G G GP G G GP G G G G G GABARAPL2 TRIM45 20562859 intact exp G GP G G G GP G GP G G G G G G G G GP G G G G G G G G G G G G GNB2L1 TRIM45 24681954 biogrid exp P P P P P P ELAVL1 TRIM45 19322201 biogrid exp G GP G G G GP G GP G G G G GP GP G G GP G G G GP G G GP G G G G G UBE2B TRIM45 24681954 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM45 UBE2D4 21143188 biogrid exp G G G G G GP G G G G G G GP GP G G GP G G G GP G G GP G G G G G UBE2E2 TRIM45 21143188 biogrid exp G GP G G G GP G GP G G G G GP GP G G GP G G G GP G G GP G G G G G TRIM45 INO80 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FLNC TRIM45 23023127 pred G GP G G G GP G GP G G G G GP G G G GP G G G GP G G GP G G G G G FLNA TRIM45 23023127 pred G G G G G GP G G G G G G GP GP G G GP G G G GP G G G G G G G G TNC TRIM45 23023127 pred G GP G G G GP G G G G G G G G G GP G GP G G G G G G G G KDELC2 TRIM45 23023127 pred G GP G G G GP G G G G G G G G G G GP G G G GP G G G G G G G G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBE2E3 TRIM45 MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_194312 prey bait TRIM45 UBE2D4 MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_194309 bait prey UBE2B TRIM45 MI:0004(affinity chromatography technology) 24681954 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_310350 prey bait UBE2D1 TRIM45 MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_194306 prey bait ELAVL1 TRIM45 MI:0096(pull down) 19322201 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_187694 bait prey UBE2E2 TRIM45 MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_194311 prey bait UBC TRIM45 MI:0004(affinity chromatography technology) 17370265 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_161307 bait prey UBE2E1 TRIM45 MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_194310 prey bait GNB2L1 TRIM45 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 24681954 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0403(colocalization) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_310255|BIOGRID_310256|BIOGRID_310257|BIOGRID_310258 prey|bait|prey|prey bait|prey|bait|bait UBE2D3 TRIM45 MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_194308 prey bait UBE2D2 TRIM45 MI:0018(two hybrid) 21143188 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_194307 prey bait

PPI - HINT Gene A Gene B PMID Method Quality GABARAPL2 TRIM45 20562859 0007 HT GABARAPL2 TRIM45 20562859 0007 HT UBE2D1 TRIM45 21143188 0018 LC UBE2E1 TRIM45 21143188 0018 LC UBE2D3 TRIM45 21143188 0018 LC UBE2D2 TRIM45 21143188 0018 LC UBE2E3 TRIM45 21143188 0018 LC UBE2E2 TRIM45 21143188 0018 LC TRIM45 TRIM45 24681954 0415 LC TRIM45 UBE2D4 21143188 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9H8W5 P51668 TRIM45 UBE2D1 0.183 21143188 Q9H8W5 P51965 TRIM45 UBE2E1 0.183 21143188 Q9H8W5 P61077 TRIM45 UBE2D3 0.183 21143188 Q9H8W5 P62837 TRIM45 UBE2D2 0.183 21143188 Q9H8W5 P63146 TRIM45 UBE2B 0.309 24681954 Q9H8W5 Q969T4 TRIM45 UBE2E3 0.183 21143188 Q9H8W5 Q96LR5 TRIM45 UBE2E2 0.183 21143188 Q9H8W5 Q9H8W5 TRIM45 TRIM45 0.332 24681954 Q9Y2X8 Q9H8W5 UBE2D4 TRIM45 0.183 21143188 Q9UBB9 Q9H8W5 TFIP11 TRIM45 0.236 unassigned1304 Q9H8W5 Q96E35 TRIM45 ZMYND19 0.236 unassigned1304 Q9H8W5 A4D127 TRIM45 MEOX2 {ECO:0000313|EMBL:EAL24289.1} 0.236 unassigned1304 Q9H8W5 Q86VP1 TRIM45 TAX1BP1 0.236 unassigned1304 Q9H8W5 P60520 TRIM45 GABARAPL2 0.332 unassigned1304,20562859 Q9H8W5 P63244 TRIM45 GNB2L1 0.623 24681954 Q9H8W5 Q15717 TRIM45 ELAVL1 0.126 19322201

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 UBC TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database TAF1 TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database HNF4A TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D1 TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E1 TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database GABARAPL2 TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D3 TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D2 TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database UBE2B TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database RACK1 TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database ELAVL1 TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E2 TRIM45 MI:0045 experimental interaction detection MI:0461 interaction database TRIM45 INO80 MI:0362 inference MI:0461 interaction database TRIM45 UBE2D4 MI:0045 experimental interaction detection MI:0461 interaction database