Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BLCA 9 77732450 77732450 + Missense_Mutation SNP C C T TCGA-DK-A1AC-01A-11D-A13W-08 TCGA-DK-A1AC-10A-01D-A13W-08 g.chr9:77732450C>T c.65C>T c.(64-66)aCg>aTg p.T22M COAD 9 77755830 77755830 + Frame_Shift_Del DEL A A - TCGA-A6-5665-01A-01D-1650-10 TCGA-A6-5665-10A-01D-1650-10 g.chr9:77755830delA c.568delA c.(568-570)aaafs p.K192fs COADREAD 9 77755830 77755830 + Frame_Shift_Del DEL A A - TCGA-A6-5665-01A-01D-1650-10 TCGA-A6-5665-10A-01D-1650-10 g.chr9:77755830delA c.568delA c.(568-570)aaafs p.K192fs ESCA 9 77742518 77742518 + Missense_Mutation SNP A A G TCGA-LN-A8I0-01A-11D-A36J-09 TCGA-LN-A8I0-10A-01D-A36M-09 g.chr9:77742518A>G c.115A>G c.(115-117)Atc>Gtc p.I39V ESCA 9 77745557 77745557 + Splice_Site SNP G G T TCGA-VR-A8EU-01A-11D-A36J-09 TCGA-VR-A8EU-10A-01D-A36M-09 g.chr9:77745557G>T c.196G>T c.(196-198)Gtg>Ttg p.V66L ESCA 9 77748217 77748217 + Missense_Mutation SNP G G T TCGA-2H-A9GF-01A-11D-A37C-09 TCGA-2H-A9GF-11A-11D-A37F-09 g.chr9:77748217G>T c.258G>T c.(256-258)ttG>ttT p.L86F GBMLGG 9 77752522 77752522 + Silent SNP T T G TCGA-FG-5965-01B-11D-1893-08 TCGA-FG-5965-10A-01D-1893-08 g.chr9:77752522T>G c.477T>G c.(475-477)ctT>ctG p.L159L HNSC 9 77755829 77755829 + Silent SNP G G A TCGA-CV-A6JM-01A-11D-A31L-08 TCGA-CV-A6JM-10A-01D-A31J-08 g.chr9:77755829G>A c.567G>A c.(565-567)ctG>ctA p.L189L LGG 9 77752522 77752522 + Silent SNP T T G TCGA-FG-5965-01B-11D-1893-08 TCGA-FG-5965-10A-01D-1893-08 g.chr9:77752522T>G c.477T>G c.(475-477)ctT>ctG p.L159L LUAD 9 77732461 77732461 + Nonsense_Mutation SNP A A T TCGA-17-Z055-01A-01W-0747-08 TCGA-17-Z055-11A-01W-0747-08 g.chr9:77732461A>T c.76A>T c.(76-78)Aga>Tga p.R26* LUAD 9 77745523 77745523 + Silent SNP C C T TCGA-55-7907-01A-11D-2167-08 TCGA-55-7907-10A-01D-2167-08 g.chr9:77745523C>T c.162C>T c.(160-162)tcC>tcT p.S54S PAAD 9 77752511 77752511 + Missense_Mutation SNP G G A TCGA-IB-A5SO-01A-11D-A32N-08 TCGA-IB-A5SO-10A-01D-A32N-08 g.chr9:77752511G>A c.466G>A c.(466-468)Gtc>Atc p.V156I

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-US 9 77732450 77732450 single base substitution C T missense_variant T22M 65C>T BOCA-FR 9 77717719 77717719 single base substitution A G intron_variant BRCA-EU 9 77700023 77700023 single base substitution A G upstream_gene_variant BRCA-EU 9 77700301 77700301 single base substitution A G upstream_gene_variant BRCA-EU 9 77700758 77700758 single base substitution C T upstream_gene_variant BRCA-EU 9 77701815 77701815 single base substitution C T upstream_gene_variant BRCA-EU 9 77701929 77701929 single base substitution C T upstream_gene_variant BRCA-EU 9 77702144 77702144 single base substitution C A upstream_gene_variant BRCA-EU 9 77702765 77702765 single base substitution C T upstream_gene_variant BRCA-EU 9 77703252 77703252 single base substitution C G upstream_gene_variant BRCA-EU 9 77703456 77703456 single base substitution C A upstream_gene_variant BRCA-EU 9 77706058 77706058 single base substitution G T intron_variant BRCA-EU 9 77706748 77706748 single base substitution C A intron_variant BRCA-EU 9 77707788 77707788 single base substitution C T intron_variant BRCA-EU 9 77708422 77708422 insertion of <=200bp - T intron_variant BRCA-EU 9 77709881 77709881 single base substitution G A intron_variant BRCA-EU 9 77710100 77710100 single base substitution C A intron_variant BRCA-EU 9 77710815 77710815 single base substitution T C intron_variant BRCA-EU 9 77711801 77711801 single base substitution T C intron_variant BRCA-EU 9 77712274 77712274 single base substitution C A intron_variant BRCA-EU 9 77712300 77712300 single base substitution T C intron_variant BRCA-EU 9 77712535 77712535 single base substitution C A intron_variant BRCA-EU 9 77712622 77712622 single base substitution C T intron_variant BRCA-EU 9 77714061 77714061 single base substitution C T intron_variant BRCA-EU 9 77714614 77714614 single base substitution G C intron_variant BRCA-EU 9 77716070 77716070 single base substitution C G intron_variant BRCA-EU 9 77717240 77717240 single base substitution G A intron_variant BRCA-EU 9 77719078 77719078 single base substitution C T intron_variant BRCA-EU 9 77719100 77719100 single base substitution C T intron_variant BRCA-EU 9 77719286 77719317 multiple base substitution (>=2bp and <=200bp) CTGTCTTTACAAAAAAATTTTTGAAAAGTTAG CACTACTA intron_variant BRCA-EU 9 77719940 77719940 single base substitution C T intron_variant BRCA-EU 9 77725371 77725371 single base substitution A T intron_variant BRCA-EU 9 77725475 77725475 single base substitution C T intron_variant BRCA-EU 9 77725922 77725922 single base substitution A G intron_variant BRCA-EU 9 77726565 77726565 single base substitution A C intron_variant BRCA-EU 9 77727500 77727500 single base substitution C T intron_variant BRCA-EU 9 77728225 77728225 single base substitution G A intron_variant BRCA-EU 9 77728755 77728755 single base substitution T C intron_variant BRCA-EU 9 77729533 77729533 single base substitution A G intron_variant BRCA-EU 9 77730118 77730118 single base substitution A T intron_variant BRCA-EU 9 77730402 77730402 single base substitution C T intron_variant BRCA-EU 9 77730840 77730840 single base substitution C T intron_variant BRCA-EU 9 77731107 77731107 single base substitution G C intron_variant BRCA-EU 9 77733588 77733588 single base substitution C T intron_variant BRCA-EU 9 77734302 77734302 single base substitution C T intron_variant BRCA-EU 9 77735191 77735191 single base substitution G C intron_variant BRCA-EU 9 77736098 77736098 single base substitution G A intron_variant BRCA-EU 9 77740704 77740704 single base substitution G T intron_variant BRCA-EU 9 77740708 77740708 single base substitution A G intron_variant BRCA-EU 9 77741326 77741326 single base substitution G A intron_variant BRCA-EU 9 77742565 77742565 single base substitution C G intron_variant BRCA-EU 9 77742705 77742705 single base substitution A G intron_variant BRCA-EU 9 77743901 77743901 single base substitution G C intron_variant BRCA-EU 9 77745833 77745833 deletion of <=200bp T - intron_variant BRCA-EU 9 77745833 77745833 insertion of <=200bp - T intron_variant BRCA-EU 9 77746617 77746617 single base substitution T C intron_variant BRCA-EU 9 77747725 77747725 single base substitution G C intron_variant BRCA-EU 9 77749895 77749895 single base substitution A G intron_variant BRCA-EU 9 77750692 77750692 single base substitution C A intron_variant BRCA-EU 9 77751131 77751131 single base substitution C T intron_variant BRCA-EU 9 77751154 77751154 single base substitution C T intron_variant BRCA-EU 9 77751566 77751566 single base substitution C A intron_variant BRCA-EU 9 77751970 77751970 single base substitution C T intron_variant BRCA-EU 9 77754146 77754146 insertion of <=200bp - CGCCATGTTA intron_variant BRCA-EU 9 77754348 77754348 insertion of <=200bp - T intron_variant BRCA-EU 9 77755638 77755638 single base substitution A T intron_variant BRCA-EU 9 77756893 77756893 single base substitution G T intron_variant BRCA-EU 9 77758614 77758614 single base substitution A C intron_variant BRCA-EU 9 77758769 77758769 single base substitution C T intron_variant BRCA-EU 9 77758775 77758775 single base substitution C T intron_variant BRCA-EU 9 77758958 77758958 single base substitution A G intron_variant BRCA-EU 9 77759127 77759127 single base substitution A T intron_variant BRCA-EU 9 77759304 77759304 deletion of <=200bp A - intron_variant BRCA-EU 9 77759547 77759547 single base substitution C A intron_variant BRCA-EU 9 77759830 77759830 single base substitution C T intron_variant BRCA-EU 9 77760485 77760485 single base substitution A G intron_variant BRCA-EU 9 77760514 77760514 single base substitution G A intron_variant BRCA-EU 9 77761769 77761769 single base substitution C T 3_prime_UTR_variant BRCA-EU 9 77763335 77763335 single base substitution T C downstream_gene_variant BRCA-EU 9 77763911 77763911 single base substitution T A downstream_gene_variant BRCA-EU 9 77764331 77764331 single base substitution G C downstream_gene_variant BRCA-EU 9 77764469 77764469 single base substitution T C downstream_gene_variant BRCA-EU 9 77764857 77764857 single base substitution C G downstream_gene_variant BRCA-EU 9 77765367 77765367 single base substitution G A downstream_gene_variant BRCA-FR 9 77700758 77700758 single base substitution C T upstream_gene_variant BRCA-FR 9 77701815 77701815 single base substitution C T upstream_gene_variant BRCA-FR 9 77702394 77702394 single base substitution G C upstream_gene_variant BRCA-FR 9 77719940 77719940 single base substitution C T intron_variant BRCA-FR 9 77733106 77733106 single base substitution G C intron_variant BRCA-FR 9 77733107 77733107 single base substitution A T intron_variant BRCA-FR 9 77736175 77736175 single base substitution C G intron_variant BRCA-FR 9 77750692 77750692 single base substitution C A intron_variant BRCA-FR 9 77759547 77759547 single base substitution C A intron_variant BRCA-FR 9 77763911 77763911 single base substitution T A downstream_gene_variant BRCA-FR 9 77764331 77764331 single base substitution G C downstream_gene_variant BRCA-UK 9 77724418 77724418 single base substitution C A intron_variant BRCA-UK 9 77725371 77725371 single base substitution A T intron_variant BRCA-UK 9 77756893 77756893 single base substitution G T intron_variant BRCA-UK 9 77761769 77761769 single base substitution C T 3_prime_UTR_variant BTCA-JP 9 77745338 77745338 single base substitution C T intron_variant BTCA-JP 9 77749119 77749119 single base substitution C G intron_variant BTCA-JP 9 77752487 77752487 single base substitution G T missense_variant A148S 442G>T BTCA-JP 9 77761575 77761575 deletion of <=200bp T - intron_variant CLLE-ES 9 77723329 77723329 single base substitution A C intron_variant CLLE-ES 9 77757595 77757595 single base substitution C T intron_variant CLLE-ES 9 77760531 77760531 single base substitution G T intron_variant COAD-US 9 77752510 77752510 single base substitution C T synonymous_variant I155I 465C>T COAD-US 9 77755830 77755830 deletion of <=200bp A - frameshift_variant K190 COCA-CN 9 77720532 77720532 single base substitution C T intron_variant COCA-CN 9 77742498 77742498 single base substitution A G missense_variant Y32C 95A>G COCA-CN 9 77745481 77745481 single base substitution C A intron_variant COCA-CN 9 77745543 77745543 single base substitution T C missense_variant I61T 182T>C COCA-CN 9 77748175 77748175 single base substitution T G intron_variant COCA-CN 9 77748203 77748203 single base substitution C A splice_region_variant COCA-CN 9 77752322 77752322 single base substitution T G intron_variant COCA-CN 9 77761607 77761607 single base substitution C T stop_gained R199* 595C>T EOPC-DE 9 77699864 77699864 single base substitution C T upstream_gene_variant EOPC-DE 9 77722439 77722439 single base substitution A G intron_variant ESAD-UK 9 77701873 77701873 single base substitution G A upstream_gene_variant ESAD-UK 9 77703471 77703471 single base substitution C A 5_prime_UTR_variant ESAD-UK 9 77703850 77703850 insertion of <=200bp - AT intron_variant ESAD-UK 9 77704404 77704404 single base substitution G A intron_variant ESAD-UK 9 77707950 77707950 single base substitution C T intron_variant ESAD-UK 9 77713531 77713531 single base substitution C T intron_variant ESAD-UK 9 77714085 77714085 single base substitution C G intron_variant ESAD-UK 9 77715029 77715029 single base substitution C A intron_variant ESAD-UK 9 77715334 77715334 single base substitution A C intron_variant ESAD-UK 9 77717412 77717412 single base substitution C G intron_variant ESAD-UK 9 77719896 77719896 single base substitution T C intron_variant ESAD-UK 9 77721941 77721941 single base substitution G A intron_variant ESAD-UK 9 77725842 77725842 single base substitution C T intron_variant ESAD-UK 9 77726322 77726322 insertion of <=200bp - GC intron_variant ESAD-UK 9 77726324 77726324 insertion of <=200bp - AG intron_variant ESAD-UK 9 77728171 77728171 single base substitution G C intron_variant ESAD-UK 9 77729621 77729621 single base substitution C T intron_variant ESAD-UK 9 77729694 77729694 single base substitution T A intron_variant ESAD-UK 9 77731979 77731979 single base substitution T C intron_variant ESAD-UK 9 77732392 77732392 single base substitution C T intron_variant ESAD-UK 9 77733762 77733762 single base substitution C T intron_variant ESAD-UK 9 77735233 77735233 single base substitution T A intron_variant ESAD-UK 9 77738890 77738890 single base substitution C T intron_variant ESAD-UK 9 77740362 77740362 single base substitution C A intron_variant ESAD-UK 9 77742091 77742091 single base substitution G T intron_variant ESAD-UK 9 77744221 77744221 single base substitution C T intron_variant ESAD-UK 9 77745445 77745445 single base substitution G T intron_variant ESAD-UK 9 77747131 77747131 single base substitution G C intron_variant ESAD-UK 9 77747594 77747594 single base substitution C T intron_variant ESAD-UK 9 77748398 77748398 single base substitution G A intron_variant ESAD-UK 9 77749068 77749068 single base substitution G C intron_variant ESAD-UK 9 77758306 77758306 insertion of <=200bp - T intron_variant ESAD-UK 9 77759095 77759095 single base substitution C T intron_variant ESAD-UK 9 77760055 77760058 deletion of <=200bp CTAT - intron_variant ESAD-UK 9 77761795 77761795 single base substitution C T 3_prime_UTR_variant ESAD-UK 9 77762474 77762474 single base substitution T C downstream_gene_variant ESAD-UK 9 77762705 77762705 single base substitution G A downstream_gene_variant ESAD-UK 9 77765244 77765244 single base substitution G T downstream_gene_variant ESAD-UK 9 77766784 77766784 single base substitution G A downstream_gene_variant ESCA-CN 9 77755766 77755766 single base substitution A C missense_variant L168F 504A>C LAML-KR 9 77748047 77748047 single base substitution C A intron_variant LAML-KR 9 77748151 77748151 single base substitution G A intron_variant LGG-US 9 77752522 77752522 single base substitution T G synonymous_variant L159L 477T>G LICA-CN 9 77755803 77755803 single base substitution A T missense_variant T181S 541A>T LICA-FR 9 77745496 77745496 single base substitution C T splice_region_variant LICA-FR 9 77764032 77764032 deletion of <=200bp A - downstream_gene_variant LINC-JP 9 77703490 77703490 single base substitution C G 5_prime_UTR_variant LINC-JP 9 77740210 77740210 single base substitution A G intron_variant LINC-JP 9 77745317 77745317 single base substitution G T intron_variant LINC-JP 9 77761837 77761837 single base substitution A G 3_prime_UTR_variant LINC-JP 9 77761930 77761930 single base substitution T C 3_prime_UTR_variant LIRI-JP 9 77702310 77702310 single base substitution G T upstream_gene_variant LIRI-JP 9 77702761 77702761 single base substitution T C upstream_gene_variant LIRI-JP 9 77703515 77703515 single base substitution G A 5_prime_UTR_variant LIRI-JP 9 77704728 77704728 single base substitution T A intron_variant LIRI-JP 9 77704943 77704943 single base substitution T C intron_variant LIRI-JP 9 77706344 77706344 single base substitution C G intron_variant LIRI-JP 9 77708599 77708599 single base substitution A G intron_variant LIRI-JP 9 77709345 77709345 single base substitution T G intron_variant LIRI-JP 9 77711991 77711991 single base substitution A G intron_variant LIRI-JP 9 77715702 77715702 deletion of <=200bp G - intron_variant LIRI-JP 9 77715968 77715968 single base substitution A G intron_variant LIRI-JP 9 77718226 77718226 single base substitution A G intron_variant LIRI-JP 9 77718258 77718258 single base substitution G C intron_variant LIRI-JP 9 77721069 77721069 single base substitution A G intron_variant LIRI-JP 9 77722188 77722188 single base substitution A G intron_variant LIRI-JP 9 77722884 77722884 single base substitution G T intron_variant LIRI-JP 9 77723464 77723464 single base substitution A G intron_variant LIRI-JP 9 77723625 77723625 single base substitution T G intron_variant LIRI-JP 9 77723823 77723823 single base substitution A G intron_variant LIRI-JP 9 77724166 77724166 single base substitution G T intron_variant LIRI-JP 9 77724681 77724681 single base substitution G C intron_variant LIRI-JP 9 77725845 77725845 single base substitution A T intron_variant LIRI-JP 9 77726433 77726433 single base substitution C T intron_variant LIRI-JP 9 77729131 77729131 single base substitution A G intron_variant LIRI-JP 9 77729201 77729201 single base substitution G A intron_variant LIRI-JP 9 77730202 77730202 single base substitution T C intron_variant LIRI-JP 9 77731896 77731896 single base substitution G T intron_variant LIRI-JP 9 77737558 77737558 single base substitution G A intron_variant LIRI-JP 9 77739423 77739423 single base substitution A G intron_variant LIRI-JP 9 77740889 77740889 single base substitution A T intron_variant LIRI-JP 9 77744564 77744564 single base substitution T A intron_variant LIRI-JP 9 77745094 77745094 single base substitution C A intron_variant LIRI-JP 9 77745178 77745179 deletion of <=200bp TG - intron_variant LIRI-JP 9 77745642 77745642 single base substitution T C intron_variant LIRI-JP 9 77745907 77745907 single base substitution C T intron_variant LIRI-JP 9 77747704 77747714 deletion of <=200bp TAGTTATAGTT - intron_variant LIRI-JP 9 77749656 77749656 single base substitution A G intron_variant LIRI-JP 9 77749907 77749907 deletion of <=200bp C - intron_variant LIRI-JP 9 77750766 77750766 single base substitution T A intron_variant LIRI-JP 9 77755799 77755799 single base substitution G A missense_variant M179I 537G>A LIRI-JP 9 77756316 77756316 single base substitution C T intron_variant LIRI-JP 9 77759764 77759764 single base substitution T C intron_variant LIRI-JP 9 77762093 77762093 single base substitution A G 3_prime_UTR_variant LIRI-JP 9 77762732 77762732 single base substitution A G downstream_gene_variant LIRI-JP 9 77763317 77763317 single base substitution A T downstream_gene_variant LIRI-JP 9 77764012 77764012 single base substitution G A downstream_gene_variant LUSC-KR 9 77698797 77698797 single base substitution T C upstream_gene_variant LUSC-KR 9 77705006 77705006 single base substitution G T intron_variant LUSC-KR 9 77706101 77706101 single base substitution A T intron_variant LUSC-KR 9 77708261 77708261 single base substitution A T intron_variant LUSC-KR 9 77711346 77711346 single base substitution C G intron_variant LUSC-KR 9 77711470 77711470 single base substitution G A intron_variant LUSC-KR 9 77713673 77713673 single base substitution A G intron_variant LUSC-KR 9 77719846 77719846 single base substitution C T intron_variant LUSC-KR 9 77723956 77723956 single base substitution G T intron_variant LUSC-KR 9 77726809 77726809 single base substitution G T intron_variant LUSC-KR 9 77730216 77730216 single base substitution A G intron_variant LUSC-KR 9 77730634 77730634 single base substitution A C intron_variant LUSC-KR 9 77732182 77732182 single base substitution C G intron_variant LUSC-KR 9 77732949 77732949 single base substitution G T intron_variant LUSC-KR 9 77742701 77742701 single base substitution A T intron_variant LUSC-KR 9 77742924 77742924 single base substitution C G intron_variant LUSC-KR 9 77748742 77748742 single base substitution A T intron_variant LUSC-KR 9 77748879 77748879 single base substitution A C intron_variant LUSC-KR 9 77753317 77753317 single base substitution G T intron_variant LUSC-KR 9 77761862 77761862 single base substitution C T 3_prime_UTR_variant LUSC-KR 9 77766940 77766940 single base substitution G T downstream_gene_variant MALY-DE 9 77706250 77706250 single base substitution C G intron_variant MALY-DE 9 77714218 77714218 single base substitution C T intron_variant MALY-DE 9 77720286 77720286 single base substitution T C intron_variant MALY-DE 9 77723157 77723157 single base substitution A T intron_variant MALY-DE 9 77723165 77723165 single base substitution T A intron_variant MALY-DE 9 77724648 77724648 single base substitution A C intron_variant MALY-DE 9 77731690 77731690 single base substitution A G intron_variant MALY-DE 9 77735509 77735509 single base substitution C T intron_variant MALY-DE 9 77741308 77741308 single base substitution A G intron_variant MALY-DE 9 77741886 77741886 single base substitution C T intron_variant MALY-DE 9 77741949 77741949 single base substitution G T intron_variant MALY-DE 9 77744719 77744719 single base substitution A G intron_variant MALY-DE 9 77751873 77751873 single base substitution C T intron_variant MALY-DE 9 77753992 77753992 single base substitution T G intron_variant MALY-DE 9 77764296 77764296 single base substitution G A downstream_gene_variant MALY-DE 9 77766673 77766673 single base substitution T A downstream_gene_variant MELA-AU 9 77700098 77700098 single base substitution G A upstream_gene_variant MELA-AU 9 77701209 77701209 single base substitution G C upstream_gene_variant MELA-AU 9 77702850 77702850 single base substitution G A upstream_gene_variant MELA-AU 9 77703952 77703952 single base substitution C T intron_variant MELA-AU 9 77704089 77704089 single base substitution C T intron_variant MELA-AU 9 77705938 77705938 single base substitution A T intron_variant MELA-AU 9 77709213 77709213 single base substitution C T intron_variant MELA-AU 9 77710814 77710814 single base substitution T C intron_variant MELA-AU 9 77711118 77711118 single base substitution C G intron_variant MELA-AU 9 77712090 77712090 single base substitution C T intron_variant MELA-AU 9 77712607 77712607 single base substitution C T intron_variant MELA-AU 9 77712842 77712842 single base substitution G T intron_variant MELA-AU 9 77713209 77713209 single base substitution C T intron_variant MELA-AU 9 77713216 77713216 single base substitution C T intron_variant MELA-AU 9 77713837 77713837 single base substitution C T intron_variant MELA-AU 9 77714598 77714598 single base substitution A T intron_variant MELA-AU 9 77714637 77714637 single base substitution C T intron_variant MELA-AU 9 77715561 77715561 single base substitution C T intron_variant MELA-AU 9 77715682 77715682 single base substitution C T intron_variant MELA-AU 9 77715779 77715779 single base substitution G A intron_variant MELA-AU 9 77715849 77715849 single base substitution C T intron_variant MELA-AU 9 77716063 77716063 single base substitution C T intron_variant MELA-AU 9 77716792 77716792 single base substitution C T intron_variant MELA-AU 9 77717218 77717218 single base substitution C T intron_variant MELA-AU 9 77718051 77718051 single base substitution A G intron_variant MELA-AU 9 77718401 77718401 single base substitution C T intron_variant MELA-AU 9 77719314 77719314 single base substitution T C intron_variant MELA-AU 9 77719375 77719375 single base substitution G A intron_variant MELA-AU 9 77719501 77719501 single base substitution G A intron_variant MELA-AU 9 77720575 77720575 single base substitution G A intron_variant MELA-AU 9 77720667 77720667 single base substitution T C intron_variant MELA-AU 9 77720737 77720737 single base substitution C T intron_variant MELA-AU 9 77721146 77721146 single base substitution C T intron_variant MELA-AU 9 77721642 77721642 single base substitution C T intron_variant MELA-AU 9 77721904 77721904 single base substitution A C intron_variant MELA-AU 9 77722803 77722803 single base substitution T A intron_variant MELA-AU 9 77723157 77723157 single base substitution A T intron_variant MELA-AU 9 77724147 77724147 single base substitution C T intron_variant MELA-AU 9 77724187 77724187 single base substitution C T intron_variant MELA-AU 9 77724645 77724646 multiple base substitution (>=2bp and <=200bp) CC TT intron_variant MELA-AU 9 77725664 77725664 single base substitution T C intron_variant MELA-AU 9 77725983 77725983 single base substitution C T intron_variant MELA-AU 9 77727485 77727485 single base substitution C T intron_variant MELA-AU 9 77727617 77727617 single base substitution C T intron_variant MELA-AU 9 77727978 77727978 single base substitution T C intron_variant MELA-AU 9 77728540 77728540 single base substitution T C intron_variant MELA-AU 9 77730535 77730535 single base substitution A G intron_variant MELA-AU 9 77731544 77731544 single base substitution C A intron_variant MELA-AU 9 77732240 77732240 single base substitution C T intron_variant MELA-AU 9 77732781 77732781 single base substitution C T intron_variant MELA-AU 9 77733445 77733445 single base substitution C T intron_variant MELA-AU 9 77734043 77734043 single base substitution C T intron_variant MELA-AU 9 77735405 77735405 single base substitution C G intron_variant MELA-AU 9 77735871 77735871 single base substitution G A intron_variant MELA-AU 9 77736090 77736090 single base substitution T A intron_variant MELA-AU 9 77736705 77736705 single base substitution C T intron_variant MELA-AU 9 77736988 77736988 single base substitution C T intron_variant MELA-AU 9 77737079 77737079 single base substitution G T intron_variant MELA-AU 9 77737121 77737121 single base substitution G A intron_variant MELA-AU 9 77738059 77738059 single base substitution C T intron_variant MELA-AU 9 77738134 77738134 single base substitution G A intron_variant MELA-AU 9 77738432 77738432 single base substitution C T intron_variant MELA-AU 9 77739328 77739328 single base substitution C T intron_variant MELA-AU 9 77739697 77739697 single base substitution C T intron_variant MELA-AU 9 77739949 77739949 single base substitution C A intron_variant MELA-AU 9 77741550 77741550 single base substitution C T intron_variant MELA-AU 9 77742351 77742351 single base substitution T C intron_variant MELA-AU 9 77742423 77742424 deletion of <=200bp TA - intron_variant MELA-AU 9 77743877 77743877 single base substitution C T intron_variant MELA-AU 9 77747324 77747324 single base substitution C T intron_variant MELA-AU 9 77747713 77747713 single base substitution T C intron_variant MELA-AU 9 77748634 77748634 single base substitution G A intron_variant MELA-AU 9 77749108 77749108 single base substitution C T intron_variant MELA-AU 9 77749207 77749207 single base substitution T G intron_variant MELA-AU 9 77749489 77749489 single base substitution C T intron_variant MELA-AU 9 77749521 77749521 single base substitution C T intron_variant MELA-AU 9 77749668 77749668 single base substitution C T intron_variant MELA-AU 9 77750640 77750640 single base substitution C T intron_variant MELA-AU 9 77750755 77750755 single base substitution A G intron_variant MELA-AU 9 77751131 77751131 single base substitution C T intron_variant MELA-AU 9 77751618 77751618 single base substitution C T intron_variant MELA-AU 9 77752082 77752082 single base substitution T C intron_variant MELA-AU 9 77752184 77752184 single base substitution C T intron_variant MELA-AU 9 77752510 77752510 single base substitution C T synonymous_variant I155I 465C>T MELA-AU 9 77752650 77752650 single base substitution C T intron_variant MELA-AU 9 77753145 77753145 single base substitution C T intron_variant MELA-AU 9 77753615 77753615 single base substitution T C intron_variant MELA-AU 9 77754347 77754347 single base substitution G A intron_variant MELA-AU 9 77754503 77754503 single base substitution C T intron_variant MELA-AU 9 77756568 77756568 single base substitution C T intron_variant MELA-AU 9 77756674 77756674 single base substitution T C intron_variant MELA-AU 9 77757602 77757602 single base substitution C T intron_variant MELA-AU 9 77758145 77758145 single base substitution A G intron_variant MELA-AU 9 77759985 77759985 single base substitution T G intron_variant MELA-AU 9 77760082 77760082 single base substitution T C intron_variant MELA-AU 9 77760118 77760118 single base substitution T C intron_variant MELA-AU 9 77760165 77760165 single base substitution C T intron_variant MELA-AU 9 77760449 77760449 single base substitution C A intron_variant MELA-AU 9 77760720 77760720 single base substitution C T intron_variant MELA-AU 9 77761130 77761130 single base substitution T A intron_variant MELA-AU 9 77762125 77762125 single base substitution C T 3_prime_UTR_variant MELA-AU 9 77762316 77762316 single base substitution C G downstream_gene_variant MELA-AU 9 77763623 77763623 single base substitution C T downstream_gene_variant MELA-AU 9 77764094 77764094 single base substitution G A downstream_gene_variant MELA-AU 9 77764398 77764398 single base substitution T C downstream_gene_variant ORCA-IN 9 77705235 77705235 single base substitution G A intron_variant ORCA-IN 9 77705241 77705241 single base substitution G A intron_variant ORCA-IN 9 77707970 77707970 single base substitution T C intron_variant ORCA-IN 9 77708724 77708724 single base substitution A G intron_variant ORCA-IN 9 77747238 77747246 deletion of <=200bp TGGGGAAGA - intron_variant OV-AU 9 77714909 77714909 single base substitution C A intron_variant OV-AU 9 77715936 77715936 single base substitution C T intron_variant OV-AU 9 77716982 77716982 single base substitution C T intron_variant OV-AU 9 77722187 77722187 single base substitution A G intron_variant OV-AU 9 77735695 77735695 single base substitution T C intron_variant OV-AU 9 77737287 77737287 single base substitution T C intron_variant OV-AU 9 77749816 77749816 single base substitution T C intron_variant OV-AU 9 77760684 77760684 single base substitution A G intron_variant PACA-AU 9 77698812 77698812 single base substitution T A upstream_gene_variant PACA-AU 9 77700599 77700599 deletion of <=200bp A - upstream_gene_variant PACA-AU 9 77702331 77702331 single base substitution C A upstream_gene_variant PACA-AU 9 77706219 77706219 single base substitution C A intron_variant PACA-AU 9 77712338 77712338 single base substitution A G intron_variant PACA-AU 9 77715349 77715349 single base substitution T A intron_variant PACA-AU 9 77720674 77720674 single base substitution C G intron_variant PACA-AU 9 77724034 77724034 deletion of <=200bp T - intron_variant PACA-AU 9 77727280 77727280 single base substitution T G intron_variant PACA-AU 9 77733319 77733319 single base substitution G T intron_variant PACA-AU 9 77734884 77734884 single base substitution A T intron_variant PACA-AU 9 77742611 77742612 deletion of <=200bp AT - intron_variant PACA-AU 9 77743462 77743462 single base substitution T A intron_variant PACA-AU 9 77747043 77747043 single base substitution G A intron_variant PACA-AU 9 77756951 77756951 single base substitution G A intron_variant PACA-AU 9 77766534 77766534 single base substitution C T downstream_gene_variant PACA-CA 9 77705882 77705882 single base substitution G A intron_variant PACA-CA 9 77707462 77707462 single base substitution T A intron_variant PACA-CA 9 77707488 77707488 insertion of <=200bp - T intron_variant PACA-CA 9 77710192 77710192 single base substitution T A intron_variant PACA-CA 9 77716166 77716166 single base substitution G A intron_variant PACA-CA 9 77716554 77716554 single base substitution C A intron_variant PACA-CA 9 77721950 77721950 single base substitution G C intron_variant PACA-CA 9 77725808 77725808 insertion of <=200bp - T intron_variant PACA-CA 9 77734772 77734772 single base substitution C G intron_variant PACA-CA 9 77736094 77736094 single base substitution G C intron_variant PACA-CA 9 77739983 77739983 deletion of <=200bp A - intron_variant PACA-CA 9 77740605 77740605 single base substitution C T intron_variant PACA-CA 9 77741055 77741055 single base substitution G A intron_variant PACA-CA 9 77742640 77742640 single base substitution C T intron_variant PACA-CA 9 77743544 77743544 single base substitution G C intron_variant PACA-CA 9 77744781 77744781 single base substitution C G intron_variant PACA-CA 9 77745587 77745587 single base substitution C G intron_variant PACA-CA 9 77746168 77746168 single base substitution G A intron_variant PACA-CA 9 77752938 77752938 single base substitution C T intron_variant PACA-CA 9 77754229 77754229 single base substitution C T intron_variant PACA-CA 9 77754264 77754264 single base substitution T C intron_variant PACA-CA 9 77755071 77755071 single base substitution T C intron_variant PACA-CA 9 77758222 77758222 single base substitution G A intron_variant PACA-CA 9 77760088 77760088 insertion of <=200bp - A intron_variant PACA-CA 9 77760543 77760543 single base substitution G A intron_variant PACA-CA 9 77764857 77764857 single base substitution C G downstream_gene_variant PACA-CA 9 77766857 77766857 single base substitution A G downstream_gene_variant PAEN-AU 9 77722824 77722824 single base substitution C T intron_variant PAEN-AU 9 77760053 77760053 single base substitution G A intron_variant PAEN-IT 9 77702522 77702522 single base substitution T A upstream_gene_variant PAEN-IT 9 77713323 77713323 single base substitution C T intron_variant PAEN-IT 9 77733445 77733445 single base substitution C T intron_variant PBCA-DE 9 77702953 77702953 deletion of <=200bp A - upstream_gene_variant PBCA-DE 9 77707455 77707455 insertion of <=200bp - T intron_variant PBCA-DE 9 77708289 77708289 single base substitution A T intron_variant PBCA-DE 9 77710848 77710848 deletion of <=200bp C - intron_variant PBCA-DE 9 77735253 77735253 single base substitution C T intron_variant PBCA-DE 9 77742331 77742331 insertion of <=200bp - GA intron_variant PBCA-DE 9 77742768 77742768 single base substitution G T intron_variant PBCA-DE 9 77753957 77753957 single base substitution T G intron_variant PBCA-DE 9 77760078 77760078 single base substitution C T intron_variant PBCA-DE 9 77760086 77760086 single base substitution T C intron_variant PBCA-DE 9 77760513 77760513 single base substitution C T intron_variant PRAD-CA 9 77699249 77699249 single base substitution T A upstream_gene_variant PRAD-CA 9 77703488 77703488 single base substitution T G 5_prime_UTR_variant PRAD-CA 9 77712785 77712785 single base substitution C T intron_variant PRAD-CA 9 77721903 77721903 single base substitution G A intron_variant PRAD-CA 9 77723161 77723161 single base substitution T A intron_variant PRAD-CA 9 77753970 77753970 single base substitution C T intron_variant PRAD-CA 9 77766322 77766322 single base substitution A G downstream_gene_variant PRAD-UK 9 77703893 77703893 single base substitution T A intron_variant PRAD-UK 9 77704015 77704015 single base substitution C G intron_variant PRAD-UK 9 77706312 77706312 single base substitution T G intron_variant PRAD-UK 9 77707463 77707463 single base substitution A T intron_variant PRAD-UK 9 77730098 77730098 single base substitution C T intron_variant PRAD-UK 9 77733063 77733063 single base substitution G A intron_variant PRAD-UK 9 77757424 77757424 single base substitution G T intron_variant PRAD-UK 9 77765923 77765923 deletion of <=200bp C - downstream_gene_variant RECA-EU 9 77700652 77700652 single base substitution T G upstream_gene_variant RECA-EU 9 77700735 77700735 single base substitution G A upstream_gene_variant RECA-EU 9 77709830 77709830 single base substitution T G intron_variant RECA-EU 9 77713487 77713487 single base substitution T A intron_variant RECA-EU 9 77722143 77722143 single base substitution A G intron_variant RECA-EU 9 77727081 77727081 single base substitution A C intron_variant RECA-EU 9 77734983 77734983 single base substitution A G intron_variant RECA-EU 9 77753974 77753974 single base substitution T C intron_variant RECA-EU 9 77753977 77753977 single base substitution T C intron_variant RECA-EU 9 77753978 77753978 single base substitution T C intron_variant RECA-EU 9 77756412 77756412 single base substitution A G intron_variant SKCA-BR 9 77701657 77701657 single base substitution T C upstream_gene_variant SKCA-BR 9 77701824 77701824 insertion of <=200bp - GTT upstream_gene_variant SKCA-BR 9 77703132 77703132 insertion of <=200bp - TGGGGC upstream_gene_variant SKCA-BR 9 77703929 77703929 single base substitution T A intron_variant SKCA-BR 9 77705210 77705214 deletion of <=200bp GGTGT - intron_variant SKCA-BR 9 77709321 77709321 single base substitution T G intron_variant SKCA-BR 9 77714272 77714272 single base substitution A C intron_variant SKCA-BR 9 77714568 77714568 single base substitution A C intron_variant SKCA-BR 9 77714981 77714981 single base substitution G A intron_variant SKCA-BR 9 77715415 77715415 single base substitution G A intron_variant SKCA-BR 9 77717463 77717463 single base substitution C T intron_variant SKCA-BR 9 77717967 77717967 single base substitution C T intron_variant SKCA-BR 9 77719539 77719539 single base substitution A G intron_variant SKCA-BR 9 77721562 77721562 insertion of <=200bp - GA intron_variant SKCA-BR 9 77727037 77727038 deletion of <=200bp CT - intron_variant SKCA-BR 9 77727974 77727974 single base substitution T G intron_variant SKCA-BR 9 77731521 77731522 deletion of <=200bp CT - intron_variant SKCA-BR 9 77732888 77732888 single base substitution T A intron_variant SKCA-BR 9 77733870 77733870 single base substitution A G intron_variant SKCA-BR 9 77734731 77734731 single base substitution T A intron_variant SKCA-BR 9 77735940 77735940 single base substitution G A intron_variant SKCA-BR 9 77738664 77738664 single base substitution T C intron_variant SKCA-BR 9 77743484 77743497 deletion of <=200bp TATATATTTTGTCC - intron_variant SKCA-BR 9 77743486 77743497 deletion of <=200bp TATATTTTGTCC - intron_variant SKCA-BR 9 77743788 77743788 single base substitution T A intron_variant SKCA-BR 9 77747888 77747910 deletion of <=200bp TACACACACACACACACACACAC - intron_variant SKCA-BR 9 77747977 77747977 single base substitution G A intron_variant SKCA-BR 9 77749226 77749226 single base substitution C T intron_variant SKCA-BR 9 77750671 77750671 single base substitution G A intron_variant SKCA-BR 9 77751407 77751407 single base substitution C T intron_variant SKCA-BR 9 77751688 77751688 single base substitution T G intron_variant SKCA-BR 9 77753943 77753943 insertion of <=200bp - CTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTT intron_variant SKCA-BR 9 77753953 77753953 single base substitution T G intron_variant SKCA-BR 9 77753969 77753969 single base substitution T G intron_variant SKCA-BR 9 77754894 77754894 single base substitution C T intron_variant SKCA-BR 9 77757858 77757858 insertion of <=200bp - CTT intron_variant SKCA-BR 9 77760955 77760955 single base substitution C T intron_variant SKCA-BR 9 77761919 77761920 deletion of <=200bp AT - 3_prime_UTR_variant SKCA-BR 9 77764318 77764318 single base substitution A G downstream_gene_variant STAD-US 9 77703615 77703615 single base substitution A T stop_gained K3* 7A>T STAD-US 9 77755767 77755767 single base substitution A G missense_variant R169G 505A>G STAD-US 9 77755814 77755814 single base substitution C T synonymous_variant A184A 552C>T THCA-SA 9 77748256 77748256 insertion of <=200bp - A frameshift_variant V99V? UCEC-US 9 77732462 77732462 single base substitution G T missense_variant R26I 77G>T

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand HCC066T COSM5821330 c.541A>T p.T181S Substitution - Missense 9:75140887-75140887 + BD96T COSM5520608 c.442G>T p.A148S Substitution - Missense 9:75137571-75137571 + TCGA-BR-6452-01 COSM3908027 c.505A>G p.R169G Substitution - Missense 9:75140851-75140851 + HCC2998 COSM1674561 c.596G>A p.R199Q Substitution - Missense 9:75146692-75146692 + PTC_285 COSM5958937 c.297_298insA p.N100fs*33 Insertion - Frameshift 9:75133340-75133341 + TCGA-D1-A174-01 COSM1110077 c.345C>T p.H115H Substitution - coding silent 9:75133388-75133388 + HT115 COSM3217272 c.395A>C p.E132A Substitution - Missense 9:75134382-75134382 + 234 COSM3730686 c.35-8delT p.? Unknown 9:75117496-75117496 + CHEWS028 COSM4588936 c.356A>G p.K119R Substitution - Missense 9:75133399-75133399 + 587376 COSM1218968 c.184C>T p.P62S Substitution - Missense 9:75130629-75130629 + C32 COSM4619353 c.412A>T p.K138* Substitution - Nonsense 9:75137541-75137541 + 07-P8041 COSM3217265 c.66G>A p.T22T Substitution - coding silent 9:75117535-75117535 + RDES COSM4588937 c.597A>G p.R199R Substitution - coding silent 9:75146693-75146693 + HCT15 COSM3217269 c.293G>A p.G98D Substitution - Missense 9:75133336-75133336 + 587362 COSM1218967 c.463A>G p.I155V Substitution - Missense 9:75137592-75137592 + YUQUEST COSM5411282 c.147G>A p.W49* Substitution - Nonsense 9:75130592-75130592 + TCGA-DK-A1AC-01 COSM1314913 c.65C>T p.T22M Substitution - Missense 9:75117534-75117534 + HCT8 COSM3217269 c.293G>A p.G98D Substitution - Missense 9:75133336-75133336 + 18T COSM106870 c.397C>T p.L133L Substitution - coding silent 9:75134384-75134384 + TCGA-AM-5821-01 COSM3763993 c.465C>T p.I155I Substitution - coding silent 9:75137594-75137594 + TCGA-A6-5665-01 COSM1462977 c.568delA p.K191fs*11 Deletion - Frameshift 9:75140914-75140914 + TCGA-AP-A0LM-01 COSM1110076 c.77G>T p.R26I Substitution - Missense 9:75117546-75117546 + PM-3 COSM5620047 c.222C>G p.D74E Substitution - Missense 9:75131795-75131795 + CHC794T COSM4954067 c.135C>T p.S45S Substitution - coding silent 9:75130580-75130580 + DLD1 COSM3217269 c.293G>A p.G98D Substitution - Missense 9:75133336-75133336 + NCI-H322M COSM1674560 c.358G>A p.D120N Substitution - Missense 9:75133401-75133401 + ESCC_BICR_007T COSM5434227 c.504A>C p.L168F Substitution - Missense 9:75140850-75140850 + RK195_C01 COSM3746046 c.537G>A p.M179I Substitution - Missense 9:75140883-75140883 + ESCC_103 COSM5638331 c.267_270delGAGA p.R90fs*12 Deletion - Frameshift 9:75133310-75133313 + 721LT COSM4382879 c.46G>C p.V16L Substitution - Missense 9:75117515-75117515 + PT37 COSM3217278 c.595C>T p.R199* Substitution - Nonsense 9:75146691-75146691 + CCK81 COSM3217271 c.377T>C p.F126S Substitution - Missense 9:75134364-75134364 + TCGA-BR-A4PD-01 COSM3908026 c.7A>T p.K3* Substitution - Nonsense 9:75088699-75088699 + Au1 COSM5597288 c.185C>T p.P62L Substitution - Missense 9:75130630-75130630 + HCC2998 COSM1674561 c.596G>A p.R199Q Substitution - Missense 9:75146692-75146692 + TCGA-FG-5965-01 COSM3930124 c.477T>G p.L159L Substitution - coding silent 9:75137606-75137606 + TCGA-CG-5721-01 COSM3908028 c.552C>T p.A184A Substitution - coding silent 9:75140898-75140898 + ccRCC-42 COSM1663292 c.112A>T p.I38F Substitution - Missense 9:75127599-75127599 + HT55 COSM3217276 c.511A>T p.I171F Substitution - Missense 9:75140857-75140857 + CHC794T COSM4954067 c.135C>T p.S45S Substitution - coding silent 9:75130580-75130580 + SNUH_G16_S1 COSM3763993 c.465C>T p.I155I Substitution - coding silent 9:75137594-75137594 + sysucc-882T COSM5447861 c.182T>C p.I61T Substitution - Missense 9:75130627-75130627 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.494192 9q13-q21.2 610180 2416638|CGAP|BC007459|C/T|coding|Ile158Ile|581|Validated

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C Missense p.T142P c.424A>C 9 77752469 BRCA A T Nonsense p.R26* c.76A>T 9 77732461 LUAD C T 3-UTRSNV . c.642+32C>T 9 77761686 CM C T IntronicSNV . c.586+1747C>T 9 77757595 CLL T G Synonymous p.L159L c.477T>G 9 77752522 LGG