PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus OASL MBD1 14728690 hprd,bci exp GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G GP G OASL SIRT7 22586326 biogrid exp GP G G G GP GP G G GP G G G G GP G G GP G G G GP G G GP G G G GP G THRA OASL 7776974 hprd exp GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G GP G OASL SEZ6L2 21988832 biogrid,intact exp P G G GP G G P G G G G G GP G G G GP G G G G GP G OASL SORT1 26496610 biogrid,intact exp G G G G GP GP G G GP G G G GP G G G GP G G G GP G G GP G G G GP G OASL TMEM63B 26496610 biogrid,intact exp G G G G G GP G G G G G G G GP G G GP G G G G G G G G G G G G CD14 OASL 26496610 biogrid,intact exp G G G G GP G G G G G G G GP GP G G G G G G G G G G G G G G G OASL TM9SF4 26496610 biogrid,intact exp GP G G G G GP G G GP G G G GP G G G GP G G G GP G G GP G G G GP G UBC OASL ortho GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G GP G ISG15 OASL 25402006, 23023127 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G GP G OASL TOLLIP 23023127 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G GP G MX1 OASL 25402006 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G G G G G GP G UBE2B OASL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G OASL CUEDC1 23023127 pred GP G G G GP GP G G GP G G G GP GP G G GP G G GP G G GP G G G P G UBE2L6 OASL 25402006 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G G G G G GP G IFI27 OASL 25402006 pred GP G G G GP GP G G GP G G G G GP G G GP G G G GP G G GP G G G G G IRF9 OASL 25402006 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G GP G OASL TRIM22 23023127 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G GP G OASL UBA2 23023127 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G G G G GP G G G GP G CXCL10 OASL 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G OASL UBQLN3 23023127 pred G G G G G G GP G CXCL11 OASL 25402006 pred P P P P P P P G P P P OASL MIDN 23023127 pred GP G G G GP GP G G GP G G G G G G G GP G G G GP G G GP G G G GP G UBE2D3 OASL 23023127 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G GP G IFIT1 OASL 25402006 pred G G G GP G G GP G G G GP GP G G GP G G G G G GP G G G GP OASL OAS3 25402006 pred GP G G G G G G G GP G G G GP GP G G G G G G GP G G G G G G GP G UBE2N OASL 23023127 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G GP G NCF2 OASL 23023127 pred G G GP G G G GP GP G G G G G G G G G G G OASL XAF1 25402006 pred G G G G GP GP G G GP G G G G G G G GP G G GP G G G G G G GP G OASL HERC5 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G GP G G G GP G OASL ESR2 25402006 pred GP G G GP GP G G GP G G GP GP G GP G G G GP G GP G G G GP IFIT2 OASL 25402006 pred G G G G GP G G G G G G G G GP G G G G G G G G G G G G G G G OAS2 OASL 25402006 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G GP G OASL IRF7 25402006 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G GP G OASL AUP1 23023127 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G GP G OAS1 OASL 25402006 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G G G P G IFI35 OASL 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HLA-F OASL 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2A OASL 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G STAT1 OASL 25402006 pred G G G G GP GP G G GP G G G GP GP G G GP G G G GP G G G G G G GP G OASL IFI44L 25402006 pred GP G G G GP GP G G GP G G G G G G G GP G G P G G GP G G G GP IFIT3 OASL 25402006 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G G G G G GP G NCF4 OASL 23023127 pred G G G GP G GP GP G G G G G G NCF4 OASL 23023127 pred G G G GP G GP GP G G G G G G OASL IFI44 25402006 pred G G G G GP GP G G GP G G G GP G G G GP G G G GP G G GP G G G GP G BCL6 OASL 23023127 pred G G G G GP G G G G G G G G GP G G G G G G GP G G G G G G G G OASL SMURF1 25402006 pred G G G G GP GP G G GP G G G GP G G G GP G G G GP G G G G G G GP G MX2 OASL 25402006 pred GP G G G GP GP G G GP G G G GP GP G G GP G G G GP G G G G G G GP G OASL RSAD2 25402006 pred G G G G GP GP G G GP G G G GP G G GP G G G GP G G GP G G G P G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q15646 Q6UXD5 two hybrid array 21988832 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B OASL SIRT7 MI:0004(affinity chromatography technology) 22586326 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_189484 prey bait THRA OASL MI:0018(two hybrid) 7776974 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_12214 - - OASL SEZ6L2 MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_286378|UniProt_117870 bait|unspecified role prey|unspecified role UBC OASL MI:0004(affinity chromatography technology)|MI:0415(enzymatic study) 21963094,21987572 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_265902|BIOGRID_162998 bait|bait prey|prey OASL MBD1 MI:0493(in vivo) 14728690 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_20059 - -

PPI - HINT Gene A Gene B PMID Method Quality CD14 OASL 26496610,26496610 0007,0004 HT OASL TMEM63B 26496610,26496610 0007,0004 HT OASL TM9SF4 26496610,26496610 0007,0004 HT OASL SORT1 26496610,26496610 0007,0004 HT CD14 OASL 26496610,26496610 0007,0004 HT OASL TMEM63B 26496610,26496610 0007,0004 HT OASL TM9SF4 26496610,26496610 0007,0004 HT OASL SORT1 26496610,26496610 0007,0004 HT THRA OASL 7776974 0018 LC OASL SEZ6L2 21988832,21988832 0397,0018 HT OASL MBD1 14728690 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q5T3F8 Q15646 TMEM63B OASL 0.126 26496610 Q9NRC8 Q15646 SIRT7 OASL 0.126 22586326 Q15646 P08571 OASL CD14 0.126 26496610 Q8K1S6 Q15646 SPIRE2 OASL 0.236 26496610 Q91W40 Q15646 KLC3 OASL 0.236 26496610 Q6UXD5 Q15646 SEZ6L2 OASL 0.286 21988832 Q3TRR0 Q15646 MAP9 OASL 0.236 26496610 Q92544 Q15646 TM9SF4 OASL 0.126 26496610 Q99523 Q15646 SORT1 OASL 0.126 26496610

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 CD14 OASL MI:0045 experimental interaction detection MI:0461 interaction database UBC OASL MI:0045 experimental interaction detection MI:0461 interaction database RAD23B OASL MI:0362 inference MI:0461 interaction database PSMD4 OASL MI:0362 inference MI:0461 interaction database SPIRE1 OASL MI:0362 inference MI:0461 interaction database SQSTM1 OASL MI:0362 inference MI:0461 interaction database NBR1 OASL MI:0362 inference MI:0461 interaction database OASL MAP9 MI:0362 inference MI:0461 interaction database OASL TMEM63B MI:0045 experimental interaction detection MI:0461 interaction database OASL KLC3 MI:0362 inference MI:0461 interaction database OASL SEZ6L2 MI:0045 experimental interaction detection MI:0461 interaction database OASL UBQLNL MI:0362 inference MI:0461 interaction database OASL SPIRE2 MI:0362 inference MI:0461 interaction database OASL TM9SF4 MI:0045 experimental interaction detection MI:0461 interaction database OASL SORT1 MI:0045 experimental interaction detection MI:0461 interaction database OASL SIRT7 MI:0045 experimental interaction detection MI:0461 interaction database OASL UBQLN4 MI:0362 inference MI:0461 interaction database OASL UBQLN2 MI:0362 inference MI:0461 interaction database OASL UBQLN1 MI:0362 inference MI:0461 interaction database OASL NUB1 MI:0362 inference MI:0461 interaction database