iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

PPI - IID
Symbol 1	Symbol 2	PMID	DBs	Evidence Type	Adipose Tissue	Adrenal Gland	Amygdala	Bone	Bone Marrow	Brain	Dorsal Root Ganglia	Eye	Heart	Hindgut	Hypothalamus	Kidney	Liver	Lung	Lymph Nodes	Mammary Gland	Midgut	Neurons	Ovary	Pancreas	Pituitary Gland	Placenta	Prostate	Salivary Gland	Skeletal Muscle	Small Intestine	Spleen	Stomach	Testes	Uterus
TAX1BP3	DTX1	23395680	biogrid	exp	P					P				P			P	P			P	P		P		P	P	P		P		P	P
UBE2E1	DTX1	19690564	biogrid,intact	exp	GP	G	G	G	G	GP	G		G	GP	G	GP	G		G	G	GP	GP		G	G	P		G	G	GP	G	GP	GP	G
EGR2	DTX1	19592273	biogrid	exp	G	G				G	G		G	G					G	G	G	G			G				G	G	G	G	G	G
UBE2D1	DTX1	19690564	biogrid,intact	exp	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	G	GP		GP	G	P	P	G	G	G	G	GP	GP	G
MAP3K1	DTX1	15684388	biogrid	exp	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
CRK	DTX1	17474147	i2d,intact	exp	GP	G	G	G	G	G	G		G	GP	G	GP	GP		G	G	GP	G		GP	G	P	P	GP	G	GP	G	GP	G	G
UBE2U	DTX1	19690564	biogrid,intact	exp	P					P				P		P	P	P			P	P		P		P	P	P		P		P	GP
DEFA5	DTX1	21988832	biogrid,intact	exp		G	G	G	G	G	G		G	G	G		G				GP	G		G	G			G	G	GP		G	G	G
UBE2C	DTX1	19690564	biogrid,intact	exp	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
NOTCH2	DTX1	9244302	hprd	exp	G	G	G	G	G	G	G		G	GP	G	G	G		G	G	G	G		G	G			G	G	G	G	GP	G	G
GRB2	DTX1	9590294	hprd,biogrid	exp	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
UBE2D3	DTX1	19690564	biogrid,intact	exp	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	G	GP		GP	G	P	P	G	G	G	G	GP	GP	G
DTX1	DTX1	11564735,12670957	hprd,biogrid	exp	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
G3BP1	DTX1	21988832	biogrid,intact	exp	GP	G	G	G	G	GP	G		G	GP	G	GP	G	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
UBE2D2	DTX1	19690564	biogrid,intact	exp	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	G	GP		GP	G	P	P	G	G	G	G	GP	GP	G
UBE2N	DTX1	19690564	biogrid,intact	exp	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
UBC	DTX1	17028573	mint,intact	exp	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
EIF3F	DTX1	21124883	biogrid	exp	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
DTX1	UBE2D4	19690564	biogrid,intact	exp	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	G	GP		GP	G	P	P	G	G	G	G	GP	GP	G
NOTCH1	DTX1	11564735,20208568,11226752, 25402006, 23023127, 21836163	hprd,biogrid	exp, ortho, pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
DTX2	DTX1	11226752, 23023127	hprd	exp, pred	GP					P			G	GP		P	GP		G		GP	P		GP	G			GP	G	P	G	GP	GP	G
DTX1	DTX3	11226752, 23023127	hprd	exp, pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP		G	G	GP	GP		P	G			GP	G	GP	G	GP	GP	G
DTX1	ITCH	17028573,18628966, 25402006	hprd,biogrid,mint,intact	exp, pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
EP300	DTX1	11564735, 25402006	hprd,biogrid	exp, pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
DTX1	DTX3L	12670957, 21836163	hprd,biogrid	exp, pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		G	G	P		GP	G	GP	G	GP	GP	G
CBLB	DTX1			ortho	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	G	G	GP	G	GP	GP	G
PRKCQ	DTX1			ortho	G	G	G	G	G	G	G		G	G	G	G	G		G	G	G	G		G	G			G	G	G	G	G	G	G
NUDT21	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
DTX1	NOTCH4	23023127		pred	G	G	G	G	G	G	G		G	G	G	G	G		G	G	G	G		G	G			G	G	G	G	G	G	G
HIF1A	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	G	P	G	G	GP	GP		GP	G	P		GP	G	GP	G	GP	GP	G
DTX1	TP63	23023127		pred	GP	G	G	G	G	G	G		G	G	G	G	G		G	G		G		G	G	P	P	G	G	G			G	G
STAT3	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
TIAM1	DTX1	23023127		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP		GP	G	GP	GP	G
NFE2	DTX1	25402006		pred	P			G	G	P				P		P	P	P			P	P		P		P	P	P		P	G	P	P
GDF11	DTX1	23023127		pred	G	G	G			G	G		G	G	G	G	G		G	G	G	G			G			G		G	G	G		G
NOV	DTX1	25402006		pred	G	G	G	G	G	G	G		G	G	G	G	G		G	G	G	G		G	G			G	G	G		G	G	G
TP73	DTX1	25402006		pred	G								G							G					G				G
DTX1	SNX9	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
RB1	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
POLR2A	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
TCF3	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
KALRN	DTX1	23023127		pred	P		G			GP	G			P	G	P	P	P			P	GP		P		P	P	P		P	G	P	P
JUN	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	G	P	G	G	GP	GP		G	G	P		GP	G	GP	G	GP	G	G
DTX1	LMX1A	23023127		pred	P					P				P		P	P	P			P	P		P		P	P	P		P		P	P
DTX1	NOTCH3	23023127		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
DTX1	PRPF19	23023127		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
SMAD7	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	P	G
DTX1	DLL4	25402006		pred	G	G		G	G	P			G	GP	G	GP	GP	P		G	GP	P		GP		P	P			GP		G	P	G
NEDD9	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP		GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
NFKBIA	DTX1	25402006		pred	G	G	G	G	G	GP	G		G	GP	G	G	G	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
RUNX1	DTX1	25402006		pred	P					P				P		P		P			P	P		P		P	P	P		P		P	P
GSK3B	DTX1	25402006		pred	G	G	G	G	G	GP	G		G	GP	G	G	G		G	G	G	GP		G	G	P		G	G	G	G	G	G	G
MMP14	DTX1	23023127		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	G	G	GP	G	GP	GP	G
ARRB2	DTX1	25402006		pred	G	G	G	G	G	G	G		G	G	G	G	G		G	G	G	G		G	G			G		G	G	G		G
VCAN	DTX1	23023127		pred	GP	G	G	G	G	GP	G		G	G	G	GP	G		G	G	G	GP		G	G	P	P	G	G	G	G	GP	G	G
YY1	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	G	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
DTX1	MIB1	23023127		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP		G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
E2F5	DTX1	25402006		pred				G	G		G					G								G				G			G		G
SS18	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
AZU1	DTX1	23023127		pred				G	G	P				P							P	P		P		P		P		P		P	P	G
DTX1	MAML1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
RUNX3	DTX1	25402006		pred	G	G		G	G		G		G	G			G		G	G	G							G		G	G	G	G	G
FGF10	DTX1	23023127		pred	P					P				P		P	P	P			P	P		GP		P	P	P		P		P	P
DTX1	NANOG	23023127		pred						P				P		G		P		G		P			G								GP
CNTN1	DTX1	23023127		pred	G	G	G			GP	G			GP	G	G	G		G	G	GP	GP		G	G			G		GP	G	GP	G	G
DTX1	CBLC	25402006		pred	P					P						P	P				GP	P		P		P	P	P		P		P	P
RUNX2	DTX1	25402006		pred	GP	G		G	G	G	G			G	G	G			G	G	G	G			G			GP		G	G	G		G
NUMB	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
DTX1	CHRD	23023127		pred	GP	G	G			GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	P	G
DTX1	ISL2	23023127		pred							G																	G
ADAM17	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
DTX1	DTX4	23023127		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	G		G	G	G	GP		GP	G	P	P	GP	G	G	G	GP	G	G
EGFR	DTX1	23023127		pred	GP	G	G			GP	G		G	GP	G	GP	GP		G	G	GP	GP		G	G	P	P	G	G	GP	G	GP	GP	G
ERBB2	DTX1	23023127		pred	GP	G	G	G	G	G	G		G	GP	G	GP	G		G	G	GP	G		G	G	P	P	G	G	GP	G	G	G	G
DTX1	CNTN4	23023127		pred	GP		G			GP	G			G	G	G	P		G		G	GP		G	G		P	P		G		G		G
DTX1	DLL3	23023127		pred			G	G	G	GP	G			P	G	P					P	GP		GP	G	P	P		G	P		P	GP	G
DTX1	DNER	23023127		pred		G	G			GP	G		G	GP	G	G			G			GP		G	G			G				GP
DTX1	LFNG	25402006		pred	GP					P				GP		P	P	P	G	G	GP	P		P		P	P	GP		GP	G	GP	P	G
NEDD4	DTX1	25402006		pred	GP	G		G	G	P	G		G	GP		GP	G	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	P	G
BMP7	DTX1	23023127		pred	G	G	G	G	G	G	G		G	G	G	G			G	G	G	G		G	G			G	G	G		G	G	G
SKI	DTX1	23023127		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	G	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
ERBB4	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP		GP	GP	G
JAG1	DTX1	25402006, 23023127		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
DTX1	CITED4	25402006		pred	GP	G	G	G	G	GP			G	P	G	G	G	P		G	G	GP		G				G	G	G	G		GP	G
AGT	DTX1	23023127		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	G	GP		GP	G	P	P	G	G	G	G	GP	GP	G
DTX1	GCM1	23023127		pred														P								P						P
MFNG	DTX1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
ARHGEF7	DTX1	23023127		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	G	G	GP	G	GP	GP	G
DTX1	MIB2	23023127		pred	P		G			GP	G		G	P	G	GP	P	P			P	GP		GP	G	P	P	GP	G	GP		P	P	G
DTX1	CNTN6	23023127		pred		G	G			GP	G			P	G	P		P			P	GP		P	G	P	P	P		P		P	P
GATA4	DTX1	25402006		pred	P					P			G	P		P	GP	P			GP	P		GP		P	P	P		GP		GP	GP
DTX1	CALCOCO1	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G
DTX1	CDX2	25402006		pred										GP							GP									GP
KIT	DTX1	23023127		pred	G	G	G	G	G	GP	G		G	G	G	G		P	G	G	G	GP		G	G			G		G	G	G	G	G
DTX1	JMY	25402006		pred	GP	G	G	G	G	GP	G		G	GP	G	GP	GP	P	G	G	GP	GP		GP	G	P	P	GP	G	GP	G	GP	GP	G

PPI - iRefIndex
UniProt A	UniProt B	Method	PMID	Interaction Type	Edge type	Num Participants
Q96J02-2	Q86Y01	affinity chromatography technology	17028573	physical association	X	2
Q96J02-2	Q86Y01	affinity chromatography technology	17028573	physical association	X	2
Q96J02-2	Q86Y01	imaging technique	17028573	colocalization	X	2
Q96J02-2	Q86Y01	pull down	18628966	direct interaction	X	2
Q86Y01	O00303	affinity chromatography technology	21124883	physical association	X	2
Q86Y01	O00303	affinity chromatography technology	21124883	physical association	X	2
Q86Y01	O00303	imaging technique	21124883	colocalization	X	2
Q86Y01		affinity chromatography technology	19592273	physical association	X	2
Q86Y01	Q01523	two hybrid	21988832	direct interaction	X	2
Q86Y01	O14907	two hybrid	23395680	direct interaction	X	2
Q86Y01	O14907	fluorescent resonance energy transfer	23395680	direct interaction	X	2
Q86Y01	Q8TDB6	affinity chromatography technology	12670957	physical association	X	2
Q86Y01	Q86Y01	affinity chromatography technology	11564735	physical association	X	2
Q86Y01	P61077-3	two hybrid	19690564	direct interaction	X	2
Q86Y01	P61088	two hybrid	19690564	direct interaction	X	2
A0A087WW00	Q86Y01	two hybrid	19690564	direct interaction	X	2
Q09472	Q86Y01	affinity chromatography technology	11564735	physical association	X	2
Q09472	Q86Y01	two hybrid	11564735	direct interaction	X	2
Q13283	Q86Y01	two hybrid	21988832	direct interaction	X	2
P0CG48	Q86Y01	affinity chromatography technology	17028573	physical association	X	2
P0CG48	Q86Y01	affinity chromatography technology	17028573	physical association	X	2
P0CG48	Q86Y01	affinity chromatography technology	21139048	physical association	X	2
Q86Y01	P46531	affinity chromatography technology	11564735	physical association	X	2
Q86Y01	P62993-2	two hybrid	9590294	direct interaction	X	2
Q86Y01	O00762	two hybrid	19690564	direct interaction	X	2
Q86Y01	P62837	two hybrid	19690564	direct interaction	X	2
Q86Y01	A0A024RA90	two hybrid	19690564	direct interaction	X	2
Q86Y01	A0A024R2K3	two hybrid	19690564	direct interaction	X	2
Q86Y01		two hybrid	19690564	direct interaction	X	2
Q86Y01	Q13233	affinity chromatography technology	15684388	physical association	X	2
Q86Y01	Q13233	pull down	15684388	direct interaction	X	2
Q86Y01	P46531	affinity chromatography technology	20208568	physical association	X	2
	Q86Y01	anti tag coimmunoprecipitation	21124883	-	C	3
	Q86Y01	anti tag coimmunoprecipitation	21124883	-	C	3
	Q86Y01	anti tag coimmunoprecipitation	21124883	-	C	3
Q9DCH4	Q86Y01	anti tag coimmunoprecipitation	21124883	physical association	X	2
Q9DCH4	Q86Y01	anti tag coimmunoprecipitation	21124883	physical association	X	2
Q9DCH4	Q86Y01	anti tag coimmunoprecipitation	21124883	physical association	X	2
Q9DCH4	Q86Y01	anti tag coimmunoprecipitation	21124883	physical association	X	2
Q9DCH4	Q86Y01	anti tag coimmunoprecipitation	21124883	physical association	X	2
Q9DCH4	Q86Y01	anti tag coimmunoprecipitation	21124883	physical association	X	2
Q9DCH4	Q86Y01	anti tag coimmunoprecipitation	21124883	physical association	X	2
Q9DCH4	Q86Y01	anti tag coimmunoprecipitation	21124883	physical association	X	2
Q9DCH4	Q86Y01	anti tag coimmunoprecipitation	21124883	physical association	X	2
Q96J02-2	Q86Y01	in vivo	17028573	-	X	2
Q96J02-2	Q86Y01	in vivo	17028573	-	X	2
Q04721	Q86Y01	in vivo	9244302	-	X	2
Q04721	Q86Y01	in vivo	9244302	-	X	2
Q86Y01	Q8TDB6	in vitro	12670957	-	X	2
Q86Y01	Q8TDB6	in vivo	12670957	-	X	2
Q86Y01	Q86Y01	in vivo	12670957	-	X	2
Q86Y01	Q86Y01	in vitro	12670957	-	X	2
Q86Y01	Q8TDB6	in vitro	12670957	-	X	2
Q86Y01	Q8TDB6	in vivo	12670957	-	X	2
Q09472	Q86Y01	in vivo	11564735	-	X	2
Q09472	Q86Y01	in vivo	11564735	-	X	2
Q86UW9-2	Q86Y01	two hybrid	11226752	-	X	2
Q86UW9-2	Q86Y01	two hybrid	11226752	-	X	2
Q86Y01	P62993-2	in vitro	9590294	-	X	2
Q86Y01	P62993-2	two hybrid	9590294	-	X	2
Q86Y01	P46531	two hybrid	11226752	-	X	2
Q86Y01	P46531	two hybrid	11226752	-	X	2
Q86Y01	P62993-2	two hybrid	9590294	-	X	2
Q86Y01	P62993-2	in vitro	9590294	-	X	2
A0A024RB96	Q86Y01	two hybrid	11226752	-	X	2
A0A024RB96	Q86Y01	two hybrid	11226752	-	X	2
A0A024QZJ2	Q86Y01	two hybrid array	19690564	physical association	X	2
Q96J02	Q86Y01	anti tag coimmunoprecipitation	17028573	physical association	X	2
Q96J02	Q86Y01	imaging technique	17028573	colocalization	X	2
P11438	Q86Y01	imaging technique	17028573	colocalization	X	2
Q86Y01	L7RT18	peptide array	17474147	physical association	X	2
Q86Y01	A0A024RDH2	two hybrid array	19690564	physical association	X	2
Q86Y01	P61088	two hybrid array	19690564	physical association	X	2
Q86Y01	Q01523	two hybrid array	21988832	physical association	X	2
Q6P289	Q86Y01	anti tag coimmunoprecipitation	17028573	physical association	X	2
Q13283	Q86Y01	two hybrid array	21988832	physical association	X	2
P0CG48	Q86Y01	anti tag coimmunoprecipitation	17028573	physical association	X	2
P0CG48	Q86Y01	anti tag coimmunoprecipitation	17028573	physical association	X	2
Q86Y01	O00762	two hybrid array	19690564	physical association	X	2
Q86Y01	A0A024RA90	two hybrid array	19690564	physical association	X	2
Q86Y01	A0A024R2K3	two hybrid array	19690564	physical association	X	2
Q86Y01	Q5VVX9	two hybrid array	19690564	physical association	X	2
Q86Y01	P62837	two hybrid array	19690564	physical association	X	2

PPI - PINA
Gene A	Gene B	Method	Publications	Species A	Species B	Interaction Type	Source Database	Interaction Identidiers	Experimental Role(s) Interactor A	Experimental Role(s) Interactor B
UBE2U	DTX1	MI:0397(two hybrid array)\|MI:0018(two hybrid)	19690564	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0915(physical association)\|MI:0407(direct interaction)	(intact)\|(biogrid)	UniProt_102634\|BIOGRID_123645	bait\|bait	prey\|prey
DTX1	ITCH	MI:0004(affinity chromatography technology)\|MI:0007(anti tag coimmunoprecipitation)\|MI:0007(anti tag coimmunoprecipitation)\|MI:0493(in vivo)\|MI:0004(affinity chromatography technology)\|MI:0007(anti tag coimmunoprecipitation)\|MI:0007(anti tag coimmunoprecipitation)\|MI:0007(anti tag coimmunoprecipitation)\|MI:0004(affinity chromatography technology)\|MI:0007(anti tag coimmunoprecipitation)\|MI:0004(affinity chromatography technology)	17028573,18628966	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0915(physical association)\|MI:0403(colocalization)\|MI:0915(physical association)\|-\|MI:0407(direct interaction)\|MI:0403(colocalization)\|MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)\|MI:0403(colocalization)\|MI:0403(colocalization)	(biogrid)\|MI:0471(mint)\|MI:0471(mint)\|MI:0468(hprd)\|(biogrid)\|(intact)\|(intact)\|MI:0471(mint)\|(biogrid)\|MI:0471(mint)\|(biogrid)	BIOGRID_201243\|MINT_51773\|MINT_51771\|HPRD_31566\|BIOGRID_116796\|UniProt_89234\|UniProt_89230\|MINT_84185\|BIOGRID_201244\|MINT_84187\|BIOGRID_201245	bait\|neutral component\|prey\|-\|prey\|neutral component\|prey\|prey\|prey\|neutral component\|prey	prey\|neutral component\|bait\|-\|bait\|neutral component\|bait\|bait\|bait\|neutral component\|bait
G3BP1	DTX1	MI:0397(two hybrid array)\|MI:0004(affinity chromatography technology)	21988832	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0915(physical association)\|MI:0407(direct interaction)	(intact)\|(biogrid)	UniProt_117562\|BIOGRID_287915	unspecified role\|prey	unspecified role\|bait
UBE2N	DTX1	MI:0397(two hybrid array)\|MI:0018(two hybrid)	19690564	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0915(physical association)\|MI:0407(direct interaction)	(intact)\|(biogrid)	UniProt_102599\|BIOGRID_123610	bait\|bait	prey\|prey
CRK	DTX1	MI:0081(peptide array)\|MI:0096(pull down)\|MI:0081(peptide array)	17474147	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0407(direct interaction)\|MI:0915(physical association)\|MI:0407(direct interaction)	MI:0471(mint)\|(intact)\|MI:0471(mint)	MINT_73445\|UniProt_91351\|MINT_43402	prey\|prey\|prey	bait\|bait\|bait
NOTCH1	DTX1	MI:0018(two hybrid)\|MI:0004(affinity chromatography technology)\|MI:0004(affinity chromatography technology)	11226752,11564735,20208568	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	-\|MI:0915(physical association)\|MI:0915(physical association)	MI:0468(hprd)\|(biogrid)\|(biogrid)	HPRD_4277\|BIOGRID_143401\|BIOGRID_91980	-\|prey\|bait	-\|bait\|prey
MAP3K1	DTX1	MI:0004(affinity chromatography technology)\|MI:0004(affinity chromatography technology)	15684388	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0407(direct interaction)\|MI:0915(physical association)	(biogrid)\|(biogrid)	BIOGRID_129240\|BIOGRID_129239	prey\|prey	bait\|bait
DTX1	DTX3	MI:0018(two hybrid)	11226752	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	-	MI:0468(hprd)	HPRD_11096	-	-
UBE2D1	DTX1	MI:0397(two hybrid array)\|MI:0018(two hybrid)	19690564	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0915(physical association)\|MI:0407(direct interaction)	(intact)\|(biogrid)	UniProt_102405\|BIOGRID_123416	bait\|bait	prey\|prey
DTX1	UBE2D4	MI:0018(two hybrid)\|MI:0397(two hybrid array)	19690564	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0407(direct interaction)\|MI:0915(physical association)	(biogrid)\|(intact)	BIOGRID_123510\|UniProt_102498	prey\|prey	bait\|bait
UBE2E1	DTX1	MI:0397(two hybrid array)\|MI:0018(two hybrid)	19690564	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0915(physical association)\|MI:0407(direct interaction)	(intact)\|(biogrid)	UniProt_102530\|BIOGRID_123540	bait\|bait	prey\|prey
DEFA5	DTX1	MI:0397(two hybrid array)\|MI:0004(affinity chromatography technology)	21988832	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0915(physical association)\|MI:0407(direct interaction)	(intact)\|(biogrid)	UniProt_117017\|BIOGRID_287269	unspecified role\|bait	unspecified role\|prey
GRB2	DTX1	MI:0492(in vitro)\|MI:0018(two hybrid)	9590294	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	-\|MI:0407(direct interaction)	MI:0468(hprd)\|(biogrid)	HPRD_4312\|BIOGRID_110403	-\|prey	-\|bait
DTX1	DTX3L	MI:0493(in vivo)\|MI:0004(affinity chromatography technology)	12670957	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	-\|MI:0915(physical association)	MI:0468(hprd)\|(biogrid)	HPRD_11097\|BIOGRID_89771	-\|bait	-\|prey
UBE2C	DTX1	MI:0397(two hybrid array)\|MI:0018(two hybrid)	19690564	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0915(physical association)\|MI:0407(direct interaction)	(intact)\|(biogrid)	UniProt_102400\|BIOGRID_123411	bait\|bait	prey\|prey
UBE2D2	DTX1	MI:0018(two hybrid)\|MI:0397(two hybrid array)	19690564	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0407(direct interaction)\|MI:0915(physical association)	(biogrid)\|(intact)	BIOGRID_123444\|UniProt_102433	bait\|bait	prey\|prey
DTX2	DTX1	MI:0018(two hybrid)	11226752	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	-	MI:0468(hprd)	HPRD_11095	-	-
EIF3F	DTX1	MI:0004(affinity chromatography technology)\|MI:0004(affinity chromatography technology)\|MI:0004(affinity chromatography technology)	21124883	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0915(physical association)\|MI:0915(physical association)\|MI:0403(colocalization)	(biogrid)\|(biogrid)\|(biogrid)	BIOGRID_199115\|BIOGRID_199117\|BIOGRID_199118	bait\|prey\|bait	prey\|bait\|prey
UBE2D3	DTX1	MI:0018(two hybrid)\|MI:0397(two hybrid array)	19690564	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0407(direct interaction)\|MI:0915(physical association)	(biogrid)\|(intact)	BIOGRID_123478\|UniProt_102468	bait\|bait	prey\|prey
NOTCH2	DTX1	MI:0493(in vivo)	9244302	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	-	MI:0468(hprd)	HPRD_6673	-	-
EGR2	DTX1	MI:0004(affinity chromatography technology)	19592273	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0915(physical association)	(biogrid)	BIOGRID_220434	bait	prey
UBC	DTX1	MI:0007(anti tag coimmunoprecipitation)\|MI:0007(anti tag coimmunoprecipitation)\|MI:0007(anti tag coimmunoprecipitation)\|MI:0007(anti tag coimmunoprecipitation)\|MI:0007(anti tag coimmunoprecipitation)\|MI:0004(affinity chromatography technology)\|MI:0007(anti tag coimmunoprecipitation)\|MI:0004(affinity chromatography technology)\|MI:0004(affinity chromatography technology)	17028573,21139048	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)	MI:0471(mint)\|MI:0471(mint)\|(intact)\|MI:0471(mint)\|MI:0471(mint)\|(biogrid)\|(intact)\|(biogrid)\|(biogrid)	MINT_84189\|MINT_84190\|UniProt_89232\|MINT_51775\|MINT_51776\|BIOGRID_170807\|UniProt_89231\|BIOGRID_201246\|BIOGRID_201247	prey\|bait\|bait\|prey\|bait\|bait\|prey\|prey\|bait	bait\|prey\|prey\|bait\|prey\|prey\|bait\|bait\|prey
EP300	DTX1	MI:0004(affinity chromatography technology)\|MI:0004(affinity chromatography technology)\|MI:0493(in vivo)	11564735	taxid:9606(Homo sapiens)	taxid:9606(Homo sapiens)	MI:0407(direct interaction)\|MI:0915(physical association)\|-	(biogrid)\|(biogrid)\|MI:0468(hprd)	BIOGRID_91983\|BIOGRID_91982\|HPRD_11094	prey\|bait\|-	bait\|prey\|-

PPI - HINT
Gene A	Gene B	PMID	Method	Quality
NOTCH1	DTX1	20208568,11564735	0004,0004	LC
DTX1	ITCH	18628966,17028573,17028573,17028573	0096,0428,0004,0007	LC
NOTCH1	DTX1	20208568,11564735	0004,0004	LC
DTX1	ITCH	18628966,17028573,17028573,17028573	0096,0428,0004,0007	LC
UBE2C	DTX1	19690564,19690564	0397,0018	HT
TAX1BP3	DTX1	23395680,23395680	0018,0055	LC
CRK	DTX1	17474147	0081	HT
NOTCH1	DTX1	11226752	0018	LC
UBE2D1	DTX1	19690564,19690564	0397,0018	HT
UBE2E1	DTX1	19690564,19690564	0397,0018	HT
UBE2D3	DTX1	19690564,19690564	0397,0018	HT
UBE2N	DTX1	19690564,19690564	0397,0018	HT
UBE2D2	DTX1	19690564,19690564	0397,0018	HT
GRB2	DTX1	9590294	0018	LC
DEFA5	DTX1	21988832,21988832	0397,0018	HT
EP300	DTX1	11564735,11564735	0018,0004	LC
G3BP1	DTX1	21988832	0397	HT
UBE2U	DTX1	19690564,19690564	0397,0018	HT
Q6ZP53	DTX1	21988832	0018	HT
DTX2	DTX1	11226752	0018	LC
DTX1	DTX3	11226752	0018	LC
DTX1	UBE2D4	19690564,19690564	0397,0018	HT
DTX1	HEL-S-71	19690564	0018	HT

PPI - Mentha
Protein A	Protein B	Gene A	Gene B	Score	PMID
Q86Y01	Q09472	DTX1	EP300	0.454	11564735
Q86Y01	P0CG48	DTX1	UBC	0.21	17028573
Q86Y01	O00303	DTX1	EIF3F	0.454	21124883
Q86Y01	O00762	DTX1	UBE2C	0.376	19690564
Q86Y01	P46108	DTX1	CRK	0.126	17474147
Q86Y01	P51668	DTX1	UBE2D1	0.376	19690564
Q86Y01	P61077	DTX1	UBE2D3	0.376	19690564
Q86Y01	P61088	DTX1	UBE2N	0.376	19690564
Q86Y01	P62837	DTX1	UBE2D2	0.376	19690564
Q86Y01	P62993	DTX1	GRB2	0.309	9590294
Q86Y01	Q86Y01	DTX1	DTX1	0.236	11564735
Q8TDB6	Q86Y01	DTX3L	DTX1	0.21	12670957
Q96J02	Q86Y01	ITCH	DTX1	0.702	17028573,18628966
Q9Y2X8	Q86Y01	UBE2D4	DTX1	0.376	19690564
Q86Y01	Q6P289	DTX1	ITCH	0.21	17028573
Q86Y01	P11161	DTX1	EGR2	0.21	19592273
Q86Y01	P11438	DTX1	LAMP1	0.126	17028573
Q86Y01	Q01523	DTX1	DEFA5	0.286	21988832
Q86Y01	Q5VVX9	DTX1	UBE2U	0.286	19690564
Q86Y01	P51965	DTX1	UBE2E1	0.286	19690564
Q86Y01	O14907	DTX1	TAX1BP3	0.523	23395680
Q86Y01	Q13233	DTX1	MAP3K1	0.454	15684388
Q86Y01	Q13283	DTX1	G3BP1	0.286	21988832
Q86Y01	P46531	DTX1	NOTCH1	0.376	11564735,20208568

PPI - InWeb_IM
Gene A	Gene B	MI 1	Interaction 1	MI 2	Interaction 2
HIP1	DTX1	MI:0362	inference	MI:0461	interaction database
EIF3F	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
WWP2	DTX1	MI:0362	inference	MI:0461	interaction database
UBE2C	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
TAX1BP3	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
FOXD2	DTX1	MI:0362	inference	MI:0461	interaction database
ARIH2	DTX1	MI:0362	inference	MI:0461	interaction database
UBB	DTX1	MI:0362	inference	MI:1106	pathways database
UBC	DTX1	MI:0045	experimental interaction detection	MI:0461,MI:1106	interaction database,pathways database
EGR2	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
SRC	DTX1	MI:0362	inference	MI:0461	interaction database
CBL	DTX1	MI:0362	inference	MI:0461	interaction database
ARRB2	DTX1	MI:0362	inference	MI:0461,MI:1106	interaction database,pathways database
FRK	DTX1	MI:0362	inference	MI:0461	interaction database
CRK	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
NOTCH1	DTX1	MI:0045	experimental interaction detection	MI:0461,MI:1106	interaction database,pathways database
ARRB1	DTX1	MI:0362	inference	MI:0461,MI:1106	interaction database,pathways database
UBE2D1	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
CCNG1	DTX1	MI:0362	inference	MI:0461	interaction database
UBE2E1	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
UBE2D3	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
UBE2N	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
PPP2CB	DTX1	MI:0362	inference	MI:0461	interaction database
UBE2D2	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
RPS27A	DTX1	MI:0362	inference	MI:1106	pathways database
UBA52	DTX1	MI:0362	inference	MI:1106	pathways database
GRB2	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
PPP2CA	DTX1	MI:0362	inference	MI:0461	interaction database
CSNK2B	DTX1	MI:0362	inference	MI:0461	interaction database
ERH	DTX1	MI:0362	inference	MI:0461	interaction database
DEFA5	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
NOTCH2	DTX1	MI:0362	inference	MI:0461	interaction database
PRKCQ	DTX1	MI:0362	inference	MI:0461	interaction database
EP300	DTX1	MI:0045	experimental interaction detection	MI:0461,MI:1106	interaction database,pathways database
SMARCB1	DTX1	MI:0362	inference	MI:0461	interaction database
CNTN1	DTX1	MI:0362	inference	MI:1106	pathways database
FOXD4	DTX1	MI:0362	inference	MI:0461	interaction database
CBLB	DTX1	MI:0362	inference	MI:0461	interaction database
MAP3K1	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
G3BP1	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
RAB32	DTX1	MI:0362	inference	MI:0461	interaction database
EIF3A	DTX1	MI:0362	inference	MI:0461	interaction database
GIT2	DTX1	MI:0362	inference	MI:0461	interaction database
ACOX1	DTX1	MI:0362	inference	MI:0461	interaction database
FOXD4L6	DTX1	MI:0362	inference	MI:0461	interaction database
UBE2U	DTX1	MI:0045	experimental interaction detection	MI:0461	interaction database
ARHGAP17	DTX1	MI:0362	inference	MI:0461	interaction database
FOXD4L3	DTX1	MI:0362	inference	MI:0461	interaction database
DTX1	DTX3	MI:0362	inference	MI:0461	interaction database
DTX1	DNER	MI:0362	inference	MI:1106	pathways database
DTX1	DTX3L	MI:0045	experimental interaction detection	MI:0461	interaction database
DTX1	FOXD4L4	MI:0362	inference	MI:0461	interaction database
DTX1	ITCH	MI:0045	experimental interaction detection	MI:0461,MI:1106	interaction database,pathways database
DTX1	WWP1	MI:0362	inference	MI:0461	interaction database
DTX1	RIBC2	MI:0362	inference	MI:0461	interaction database
DTX1	DHX35	MI:0362	inference	MI:0461	interaction database
DTX1	HEYL	MI:0362	inference	MI:0461	interaction database
DTX1	IFT46	MI:0362	inference	MI:0461	interaction database
DTX1	FOXD4L1	MI:0362	inference	MI:0461	interaction database
DTX1	HEY2	MI:0362	inference	MI:0461	interaction database
DTX1	HMGXB4	MI:0362	inference	MI:0461	interaction database
DTX1	FOXD3	MI:0362	inference	MI:0461	interaction database
DTX1	NOTCH3	MI:0362	inference	MI:0461	interaction database
DTX1	EXO1	MI:0362	inference	MI:0461	interaction database
DTX1	GIT1	MI:0362	inference	MI:0461	interaction database
DTX1	UBE2D4	MI:0045	experimental interaction detection	MI:0461	interaction database
DTX1	HBS1L	MI:0362	inference	MI:0461	interaction database
DTX1	HEY1	MI:0362	inference	MI:0461	interaction database