PTM - CPLM Gene Name UniProt ID Type Position Code USP37; KIAA1594 Q86T82 Ubiquitination 327 K USP37; KIAA1594 Q86T82 Ubiquitination 540 K USP37; KIAA1594 Q86T82 Ubiquitination 635 K USP37; KIAA1594 Q86T82 Ubiquitination 544 K USP37; KIAA1594 Q86T82 Ubiquitination 973 K USP37; KIAA1594 Q86T82 Ubiquitination 916 K USP37; KIAA1594 Q86T82 Ubiquitination 68 K USP37; KIAA1594 Q86T82 Ubiquitination 147 K USP37; KIAA1594 Q86T82 Ubiquitination 315 K USP37; KIAA1594 Q86T82 Ubiquitination 452 K USP37; KIAA1594 Q86T82 Ubiquitination 915 K USP37; KIAA1594 Q86T82 Ubiquitination 962 K USP37; KIAA1594 Q86T82 Ubiquitination 378 K USP37; KIAA1594 Q86T82 Ubiquitination 785 K USP37; KIAA1594 Q86T82 Ubiquitination 717 K

PTM - dbPAF Gene Name UniProt ID Position Type Species USP37; KIAA1594 Q86T82 114 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 138 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 170 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 191 T Homo sapiens(Human) USP37; KIAA1594 Q86T82 2 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 210 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 211 T Homo sapiens(Human) USP37; KIAA1594 Q86T82 213 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 219 Y Homo sapiens(Human) USP37; KIAA1594 Q86T82 227 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 268 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 301 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 312 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 415 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 417 T Homo sapiens(Human) USP37; KIAA1594 Q86T82 457 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 462 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 573 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 624 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 627 T Homo sapiens(Human) USP37; KIAA1594 Q86T82 628 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 630 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 631 T Homo sapiens(Human) USP37; KIAA1594 Q86T82 633 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 643 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 650 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 652 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 683 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 698 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 770 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 80 S Homo sapiens(Human) USP37; KIAA1594 Q86T82 83 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q86T82 K446-ac Acetylation QLKEDMEkLNKTWkT Q86T82 R168-m1 Methylation KVLGNPGrGsIKTVA Q86T82 R288-m1 Methylation SGGTNLDrTNVSSQT Q86T82 S2-p Phosphorylation ______MsPLKIHGP Q86T82 S80-p Phosphorylation MLTLQDNsFLsIDKV Q86T82 S83-p Phosphorylation LQDNsFLsIDKVPSK Q86T82 S114-p Phosphorylation LPAAMKPsQGSGSFG Q86T82 S138-p Phosphorylation KETSRQLsYSDNQAS Q86T82 S150-p Phosphorylation QASAKRGsLETKDDI Q86T82 S170-p Phosphorylation LGNPGrGsIKTVAGS Q86T82 T191-p Phosphorylation PSLTSTStPLRSGLL Q86T82 S210-p Phosphorylation EKRKRMIstGsELNE Q86T82 T211-p Phosphorylation KRKRMIstGsELNED Q86T82 S213-p Phosphorylation KRMIstGsELNEDyP Q86T82 Y219-p Phosphorylation GsELNEDyPKENDSS Q86T82 S227-p Phosphorylation PKENDSSsNNKAMTD Q86T82 S268-p Phosphorylation LLPLQSSsFYGSRAG Q86T82 S301-p Phosphorylation QTPSAKRsLGFLPQP Q86T82 S312-p Phosphorylation LPQPVPLsVKKLRCN Q86T82 S415-p Phosphorylation KKVKNAIsAtAERFS Q86T82 T417-p Phosphorylation VKNAIsAtAERFSGY Q86T82 S457-p Phosphorylation TWkTEPVsGEENsPD Q86T82 S462-p Phosphorylation PVsGEENsPDISATR Q86T82 S573-p Phosphorylation YSFNVALsLNNKIGQ Q86T82 S624-p Phosphorylation KASQMVNsCItsPSt Q86T82 T627-p Phosphorylation QMVNsCItsPStPSK Q86T82 S628-p Phosphorylation MVNsCItsPStPSKK Q86T82 T631-p Phosphorylation sCItsPStPSKKFTF Q86T82 S650-p Phosphorylation SLALCLDsDsEDELK Q86T82 S652-p Phosphorylation ALCLDsDsEDELKRS Q86T82 S683-p Phosphorylation QEDLEKDsKLCPIEP Q86T82 S698-p Phosphorylation DKSELENsGFDRMSE Q86T82 S770-p Phosphorylation ITELDPAsFTEITKD Q86T82 K452-sm Sumoylation EkLNKTWkTEPVsGE Q86T82 K327-ub Ubiquitination QDYTGWNkPRVPLSS Q86T82 K452-ub Ubiquitination EkLNKTWkTEPVsGE Q86T82 K962-ub Ubiquitination DELLETEkNSQSLST Q86T82 K973-ub Ubiquitination SLSTEVGkTTRQAL_

PTM - dbPTM UniProt ID Position Code Type Resources References Q86T82 628 S Phosphorylation Swiss-Prot 1010711 21596315 Q86T82 650 S Phosphorylation Swiss-Prot 1010711 17081983;18669648;19413330 Q86T82 652 S Phosphorylation Swiss-Prot 1010711 17081983;18187866;18669648 Q86T82 650 S Phosphorylation PhosphoELM.10011 18669648 Q86T82 652 S Phosphorylation PhosphoELM.10011 18669648 Q86T82 452 K Ubiquitylation Phosphositeplus.1010730 21906983 Q86T82 962 K Ubiquitylation Phosphositeplus.1010730 21906983 Q86T82 973 K Ubiquitylation Phosphositeplus.1010730 21906983 Q86T82 628 S Phosphorylation Phosphositeplus.1010730 21596315 Q86T82 650 S Phosphorylation Phosphositeplus.1010730 18669648;21659604 Q86T82 652 S Phosphorylation Phosphositeplus.1010730 18187866;18669648;21659604 Q86T82 650 S Phosphorylation HPRD 9.0 17081983,18669648,19413330 Q86T82 652 S Phosphorylation HPRD 9.0 17081983,18669648 Q86T82 650 S Phosphorylation SysPTM 1.1 18669648;17081983 Q86T82 652 S Phosphorylation SysPTM 1.1 18669648;17081983

PTM - HPRD Symbol Position Code Type References USP37 650 S Phosphorylation 17081983,18669648,19413330 USP37 652 S Phosphorylation 17081983,18669648

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q86T82 650 S 18669648 HTP Phosphorylation Q86T82 652 S 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q86T82 170 Phosphoserine 23186163 Q86T82 210 Phosphoserine 23186163 Q86T82 628 Phosphoserine; by CDK2 21596315;27296872 Q86T82 650 Phosphoserine 18669648 Q86T82 652 Phosphoserine 18669648 Q86T82 770 Phosphoserine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type USP37 IPI00472977 S 650 LALCLDpSDSEDEL phosphorylation USP37 IPI00472977 S 652 LCLDSDpSEDELKR phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 57695 121720 - K Ubiquitination 22118674 57695 121720 - K Ubiquitination 21139048 57695 121720 - K Ubiquitination 21906983 57695 121720 - K Ubiquitination 21596315 57695 121720 - K Ubiquitination 23027877 57695 121720 - K Ubiquitination 24324262 57695 121720 - K Sumoylation 25391492 57695 121720 - K Ubiquitination 25347529

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID USP37 Homo sapiens (Human) 973; 962; 452 "973,LSTEVGKTTRQAS; 962,ELLETEKNSQSLS; 452,KLNKTWKTEPVSG" 973:21906983; 962:21906983; 452:21906983