PTM - CPLM Gene Name UniProt ID Type Position Code BARD1 Q99728 Acetylation 124 K BARD1 Q99728 Acetylation 371 K BARD1 Q99728 Ubiquitination 423 K BARD1 Q99728 Ubiquitination 160 K BARD1 Q99728 Ubiquitination 171 K BARD1 Q99728 Ubiquitination 110 K

PTM - dbPAF Gene Name UniProt ID Position Type Species BARD1 Q99728 148 S Homo sapiens(Human) BARD1 Q99728 184 S Homo sapiens(Human) BARD1 Q99728 186 S Homo sapiens(Human) BARD1 Q99728 192 S Homo sapiens(Human) BARD1 Q99728 244 S Homo sapiens(Human) BARD1 Q99728 251 S Homo sapiens(Human) BARD1 Q99728 288 S Homo sapiens(Human) BARD1 Q99728 299 T Homo sapiens(Human) BARD1 Q99728 307 Y Homo sapiens(Human) BARD1 Q99728 313 S Homo sapiens(Human) BARD1 Q99728 330 S Homo sapiens(Human) BARD1 Q99728 342 S Homo sapiens(Human) BARD1 Q99728 344 S Homo sapiens(Human) BARD1 Q99728 363 S Homo sapiens(Human) BARD1 Q99728 364 S Homo sapiens(Human) BARD1 Q99728 367 S Homo sapiens(Human) BARD1 Q99728 389 S Homo sapiens(Human) BARD1 Q99728 391 S Homo sapiens(Human) BARD1 Q99728 394 T Homo sapiens(Human) BARD1 Q99728 398 T Homo sapiens(Human) BARD1 Q99728 402 S Homo sapiens(Human) BARD1 Q99728 409 S Homo sapiens(Human) BARD1 Q99728 410 S Homo sapiens(Human) BARD1 Q99728 412 S Homo sapiens(Human) BARD1 Q99728 430 T Homo sapiens(Human) BARD1 Q99728 443 S Homo sapiens(Human) BARD1 Q99728 446 Y Homo sapiens(Human) BARD1 Q99728 496 S Homo sapiens(Human) BARD1 Q99728 538 S Homo sapiens(Human) BARD1 Q99728 586 S Homo sapiens(Human) BARD1 Q99728 704 S Homo sapiens(Human) BARD1 Q99728 714 T Homo sapiens(Human) BARD1 Q99728 719 T Homo sapiens(Human) BARD1 Q99728 734 T Homo sapiens(Human)

PTM - PhosSNP Gene Name dbSNP ID Gene Mutation AA Mutation Mutation Position Code Peptide Score Modification Type BARD1 rs16852741 AGT->GGT S->G 186 S SYEFVSPSPPADVSE 186 Phosphorylation TypeI- BARD1 rs13389423 TCT->TTT S->F 734 T DSDQRFCTQYIIYED 734 Phosphorylation TypeII- BARD1 rs16852741 AGT->GGT S->G 184 S QDSYEFVSPSPPADV 184 Phosphorylation TypeIII-

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q99728 K124-ac Acetylation DNELSDLkEDKPRKS Q99728 K152-ac Acetylation MWFsPRSkKVRYVVS Q99728 K371-ac Acetylation sPPsCKRkVGGTSGR Q99728 S148-p Phosphorylation NSIkMWFsPRSkKVR Q99728 S184-p Phosphorylation QDSYEFVsPsPPADV Q99728 S186-p Phosphorylation SYEFVsPsPPADVsE Q99728 S192-p Phosphorylation PsPPADVsERAKKAS Q99728 S244-p Phosphorylation QKLVSFCsQPSVISs Q99728 S251-p Phosphorylation sQPSVISsPQINGEI Q99728 S288-p Phosphorylation PLAEQIEsPDTKSRN Q99728 T299-p Phosphorylation KSRNEVVtPEKVCkN Q99728 Y307-p Phosphorylation PEKVCkNyLTSKKsL Q99728 S313-p Phosphorylation NyLTSKKsLPLENNG Q99728 S330-p Phosphorylation GHHNRLSsPISKRCR Q99728 S342-p Phosphorylation RCRTSILsTsGDFVK Q99728 S344-p Phosphorylation RTSILsTsGDFVKQT Q99728 S364-p Phosphorylation IPLPECSsPPsCKRk Q99728 S367-p Phosphorylation PECSsPPsCKRkVGG Q99728 S391-p Phosphorylation SDEFISLsPGtPPSt Q99728 T394-p Phosphorylation FISLsPGtPPStLSS Q99728 T398-p Phosphorylation sPGtPPStLSSsSYR Q99728 S402-p Phosphorylation PPStLSSsSYRRVMS Q99728 S410-p Phosphorylation SYRRVMSsPsAMKLL Q99728 S412-p Phosphorylation RRVMSsPsAMKLLPN Q99728 T430-p Phosphorylation kRNHRGEtLLHIASI Q99728 S443-p Phosphorylation SIKGDIPsVEyLLQN Q99728 Y446-p Phosphorylation GDIPsVEyLLQNGSD Q99728 S496-p Phosphorylation TTGYQNDsPLHDAAK Q99728 S586-p Phosphorylation SEQQKMLsELAVILK Q99728 S704-p Phosphorylation AGGGQILsRKPKPDS Q99728 T714-p Phosphorylation PKPDSDVtQTINtVA Q99728 T719-p Phosphorylation DVtQTINtVAYHARP Q99728 T734-p Phosphorylation DSDQRFCtQYIIYED Q99728 K46-sm Sumoylation AALDRLEkLLRCSRC Q99728 K144-sm Sumoylation GNKKNSIkMWFsPRS Q99728 K170-sm Sumoylation VQTQPAIkKDASAQQ Q99728 K217-sm Sumoylation TLAEINQkWNLEAEK Q99728 K305-sm Sumoylation VtPEKVCkNyLTSKK Q99728 K423-sm Sumoylation LLPNMAVkRNHRGEt Q99728 K548-sm Sumoylation SLLLLPEkNESSSAS Q99728 K160-ub Ubiquitination KVRYVVSkASVQTQP Q99728 K423-ub Ubiquitination LLPNMAVkRNHRGEt

PTM - dbPTM UniProt ID Position Code Type Resources References Q99728 148 S Phosphorylation Swiss-Prot 1010711 18669648 Q99728 186 S Phosphorylation Swiss-Prot 1010711 19690332 Q99728 364 S Phosphorylation Swiss-Prot 1010711 19413330 Q99728 391 S Phosphorylation Swiss-Prot 1010711 18669648;19690332 Q99728 394 T Phosphorylation Swiss-Prot 1010711 18669648;19690332 Q99728 423 K Ubiquitylation Swiss-Prot 1010711 17370265 Q99728 148 S Phosphorylation PhosphoELM.10011 18669648 Q99728 391 S Phosphorylation PhosphoELM.10011 18669648 Q99728 394 T Phosphorylation PhosphoELM.10011 18669648 Q99728 160 K Ubiquitylation Phosphositeplus.1010730 21890473 Q99728 423 K Ubiquitylation Phosphositeplus.1010730 17370265 Q99728 124 K Acetylation Phosphositeplus.1010730 20167786 Q99728 371 K Acetylation Phosphositeplus.1010730 20167786 Q99728 148 S Phosphorylation Phosphositeplus.1010730 15665273;15855157;18669648;20068231 Q99728 184 S Phosphorylation Phosphositeplus.1010730 15855157 Q99728 186 S Phosphorylation Phosphositeplus.1010730 15855157;19690332;20068231 Q99728 192 S Phosphorylation Phosphositeplus.1010730 19690332 Q99728 251 S Phosphorylation Phosphositeplus.1010730 15665273;15855157 Q99728 288 S Phosphorylation Phosphositeplus.1010730 15665273 Q99728 391 S Phosphorylation Phosphositeplus.1010730 15855157;18669648;19690332;20068231 Q99728 410 S Phosphorylation Phosphositeplus.1010730 22115753 Q99728 299 T Phosphorylation Phosphositeplus.1010730 15665273;15855157;22115753 Q99728 394 T Phosphorylation Phosphositeplus.1010730 15855157;18669648;19690332;20068231 Q99728 714 T Phosphorylation Phosphositeplus.1010730 16651405 Q99728 734 T Phosphorylation Phosphositeplus.1010730 16651405 Q99728 148 S Phosphorylation HPRD 9.0 15855157,18669648,20068231 Q99728 184 S Phosphorylation HPRD 9.0 15855157 Q99728 186 S Phosphorylation HPRD 9.0 15855157,20068231 Q99728 251 S Phosphorylation HPRD 9.0 15855157 Q99728 330 S Phosphorylation HPRD 9.0 20068231 Q99728 364 S Phosphorylation HPRD 9.0 19413330 Q99728 391 S Phosphorylation HPRD 9.0 15855157,18669648,20068231 Q99728 299 T Phosphorylation HPRD 9.0 15855157 Q99728 394 T Phosphorylation HPRD 9.0 15855157,18669648,20068231 Q99728 148 S Phosphorylation SysPTM 1.1 18669648 Q99728 391 S Phosphorylation SysPTM 1.1 18669648 Q99728 394 T Phosphorylation SysPTM 1.1 18669648

PTM - HPRD Symbol Position Code Type References BARD1 148 S Phosphorylation 15855157,18669648,20068231 BARD1 184 S Phosphorylation 15855157 BARD1 186 S Phosphorylation 15855157,20068231 BARD1 251 S Phosphorylation 15855157 BARD1 299 T Phosphorylation 15855157 BARD1 330 S Phosphorylation 20068231 BARD1 364 S Phosphorylation 19413330 BARD1 391 S Phosphorylation 15855157,18669648,20068231 BARD1 394 T Phosphorylation 15855157,18669648,20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q99728 391 S 18669648 HTP Phosphorylation Q99728 148 S 18669648 HTP Phosphorylation Q99728 394 T 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q99728 186 Phosphoserine 23186163 Q99728 299 Phosphothreonine 23186163 Q99728 391 Phosphoserine 18669648 Q99728 394 Phosphothreonine 18669648

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 580 107056 - K Ubiquitination 21890473 580 107056 - K Sumoylation 25391492 580 107056 - K Ubiquitination 11927591

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID BARD1 Homo sapiens (Human) 160 "160,VRYVVSKASVQTQ" 160:21890473 BARD1 Homo sapiens (Human) 160; 423 "160,VRYVVSKASVQTQ; 423,LPNMAVKRNHRGE" 160:21890473; 423:17370265 BARD1 Homo sapiens (Human) 16 "16,VRYVVSKASVQTQ" 16:21890473 BARD1 Homo sapiens (Human) 160 "160,VRYVVSKASVQTQ" 160:21890473 BARD1 Homo sapiens (Human) 160 "160,VRYVVSKASVQTQ" 160:21890473