Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 2 203745885 rs6725887 T C rs6725887 1.00E-08 Myocardial infarction (early onset) HPOID:0001658 DOID:5844 C intron GWASdb_trait 2 203745885 rs6725887 T C rs6725887 3.36E-05 Cardiovascular disease risk factors HPOID:0001626 DOID:1287 C intron GWASdb_trait 2 203745885 rs6725887 T C rs6725887 1.00E-08 Coronary heart disease HPOID:0001677 DOID:3393 C intron GWASdb_trait 2 203745885 rs6725887 T C rs6725887 1.00E-09 Coronary heart disease HPOID:0001677 DOID:3393 C intron GWASdb_trait 2 203745885 rs6725887 T C rs6725887 1.12E-09 Pericardial fat HPOID:0001717|HPOID:0001658 DOID:5844 C intron GWASdb_trait 2 203745885 rs6725887 T C rs6725887 0.000000148 Coronary artery disease (CAD) age >50 NA NA C intron GWASdb_trait 2 203745885 rs6725887 T C rs6725887 0.000000188 Coronary artery disease (CAD) (males) NA NA C intron GWASdb_trait 2 203745885 rs6725887 T C rs6725887 0.00017 Coronary artery disease (CAD) age <=50 NA NA C intron GWASdb_trait 2 203745885 rs6725887 T C rs6725887 5.51E-10 Coronary artery disease with myocardial infarction HPOID:0001677|HPOID:0001658 DOID:3393|DOID:5844 C intron GWASdb_trait 2 203745885 rs6725887 T C rs6725887 6.55E-08 Coronary artery disease (CAD) (females) NA NA C intron GWASdb_trait 2 203745885 rs6725887 T C rs6725887 2.00E-08 Coronary artery disease HPOID:0001677 DOID:3393 C intron GWASdb_trait 2 203753072 rs7582720 T C rs7582720 3.00E-08 Coronary artery disease or large artery stroke HPOID:0001677|HPOID:0002140 DOID:3393|DOID:6713 C intron GWASdb_trait 2 203753072 rs7582720 T C rs7582720 4.00E-09 Coronary artery disease or ischemic stroke HPOID:0001677|HPOID:0002140 DOID:3393|DOID:6713 C intron GWASdb_trait 2 203766367 rs3933629 T C rs3933629 3.30E-11 Butyrylcholinesterase levels HPOID:0001513 DOID:9970 T intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs6725887 2 203745885 203745885 intronic 0.676645 0.169639123010035 GWAS of prostate cancer rs7582720 2 203753072 203753072 intronic 0.657982 0.18178598694470702

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000138442.9 WDR12 616620