Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 2 204213503 rs6435185 T C rs6435185 1.10E-04 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 2 204226003 rs12474416 G T rs12474416 3.80E-08 Butyrylcholinesterase levels HPOID:0001513 DOID:9970 G intron GWASdb_trait 2 204226331 rs12466364 A G rs12466364 3.80E-08 Butyrylcholinesterase levels HPOID:0001513 DOID:9970 A intron GWASdb_trait 2 204241639 rs11686036 A G rs11686036 9.10E-18 Butyrylcholinesterase levels HPOID:0001513 DOID:9970 A intron GWASdb_trait 2 204249399 rs11675251 A G rs11675251 4.00E-18 Butyrylcholinesterase levels HPOID:0001513 DOID:9970 A intron GWASdb_trait 2 204266343 rs3769676 T C rs3769676 3.70E-15 Butyrylcholinesterase levels HPOID:0001513 DOID:9970 T intron GWASdb_trait 2 204272090 rs1376877 C T rs1376877 4.00E-07 Subclinical atherosclerosis HPOID:0002621 DOID:1936 C intron GWASdb_trait 2 204272090 rs1376877 C T rs1376877 1.50E-17 Butyrylcholinesterase levels HPOID:0001513 DOID:9970 C intron GWASdb_trait 2 204276327 rs3769678 T C rs3769678 1.50E-17 Butyrylcholinesterase levels HPOID:0001513 DOID:9970 T intron GWASdb_trait 2 204287133 rs2255047 G A rs2255047 4.90E-04 Type 2 diabetes HPOID:0005978 DOID:9352 G intron GWASdb_trait 2 204292517 rs2469954 T C rs2469954 2.80E-15 Butyrylcholinesterase levels HPOID:0001513 DOID:9970 G UTR-3 GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs2255047 2 204287133 204287133 intronic 0.880227 0.0554053140607706 GWAS of prostate cancer rs3769676 2 204266343 204266343 intronic 0.634741 0.19740344827708

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000138443.15 ABI2 606442