PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus TRIM28 SENP7 24018422 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P SUMO2 SENP7 24018422 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P BCL6 SENP7 16147992 biogrid,intact exp G G G G GP G G G G G G G G GP G G G G G P G G G G GP G CBX5 SENP7 24018422,20562864 biogrid,intact exp, ortho GP GP G G GP GP G G GP G GP G GP GP G GP GP GP P G P GP GP G GP GP GP P CBX1 SENP7 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P CBX3 SENP7 ortho GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P WRNIP1 SENP7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P SENP7 CBX8 21836163 pred P P P P P P P P P P P P P P P P P P P P MED6 SENP7 21836163 pred GP GP P P P GP GP GP GP GP G GP P GP P G P G P G P GP GP P SENP7 DCSTAMP 21836163 pred P G GP G G P P G G P G G G P P P SUMO1 SENP7 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP P G P GP GP GP GP GP GP P SENP7 SMURF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G SMC5 SENP7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G P GP GP GP GP GP GP P SENP7 PHAX 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G SENP7 MTG2 21836163 pred GP GP G G GP GP G GP GP G GP G G GP G GP GP GP P G GP G G GP G GP P UBE2D1 SENP7 21836163 pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP P G P GP G GP G GP GP P SENP7 CPSF2 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P LEO1 SENP7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P SENP7 UBA2 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP P G2E3 SENP7 21836163 pred G G G G G GP G G GP G GP G G G G G GP G G G G G G G G CPSF3L SENP7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P UBXN4 SENP7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P ZBTB14 SENP7 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP P G P GP GP G GP G GP P SENP7 INTS9 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G TNIP3 SENP7 21836163 pred P P P P P P P P P P P P P P P P P P P CALCOCO2 SENP7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP G GP P UBE2E1 SENP7 21836163 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G P G G GP GP G GP P SENP7 GEMIN8 21836163 pred GP GP G G GP GP G GP GP G GP P GP P G P GP G P G P GP GP GP GP GP GP P UBE2L3 SENP7 21836163 pred GP G G G G GP G GP GP G GP G G G G GP GP G P G G GP GP GP G GP P SENP7 RBCK1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P SP100 SENP7 21836163 pred GP GP G GP P G GP GP GP GP GP GP G GP P GP P G P GP GP GP GP GP GP P MIB2 SENP7 21836163 pred P P G GP G GP P G GP P P P P GP GP P G P GP GP GP GP P P P NEDD8 SENP7 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P SENP7 DAXX 21836163, 21836163, 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P MORC3 SENP7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P DEAF1 SENP7 21836163 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P GEMIN6 SENP7 21836163 pred GP GP G GP P G GP GP GP GP GP GP G GP P G P G P GP GP GP GP GP GP P USP7 SENP7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P SENP7 WBP11 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P SENP7 SAP30L 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G SENP7 21836163 pred GTPBP10 SENP7 21836163 pred GP GP G G G GP G G GP G GP G GP GP G GP GP G P G P GP GP GP GP GP GP P SKIV2L2 SENP7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9BQF6 anti tag coimmunoprecipitation 20562864 association C 84 Q9BQF6 anti bait coimmunoprecipitation 16147992 association C 64 Q13263 Q9BQF6 anti tag coimmunoprecipitation 24018422 physical association X 2 Q13263 Q9BQF6 anti tag coimmunoprecipitation 24018422 physical association X 2 Q9BQF6 P45973 anti tag coimmunoprecipitation 24018422 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality CBX5 SENP7 20562864,24018422 0007,0007 LC SENP7 HEL25 24018422,20562864 0004,0004 LC CBX5 SENP7 20562864,24018422 0007,0007 LC SENP7 HEL25 24018422,20562864 0004,0004 LC TRIM28 SENP7 24018422,24018422,24018422 0004,0415,0007 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9BQF6 P41182 SENP7 BCL6 0.236 16147992 Q9BQF6 P45973 SENP7 CBX5 0.671 27705803,24018422,20562864 Q9BQF6 O14950 SENP7 MYL12B 0.126 27705803 Q9BQF6 P01040 SENP7 CSTA 0.126 27705803 Q9BQF6 P61956 SENP7 SUMO2 0.309 24018422 Q9BQF6 Q09028 SENP7 RBBP4 0.126 27705803 Q9BQF6 Q13185 SENP7 CBX3 0.236 27705803 Q9BQF6 Q5TGY3 SENP7 AHDC1 0.126 27705803 Q9BQF6 Q96JM3 SENP7 CHAMP1 0.126 27705803 Q9BQF6 Q13263 SENP7 TRIM28 0.623 24018422,27705803