PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus HSP90AA1 MARCH9 22939624 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MARCH9 ULBP1 20870941 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G MARCH9 MARCH9 17174307 hprd,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HSP90AB1 MARCH9 22939624 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CTSD MARCH9 17174307 mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q86YJ5 Q9BZM6 affinity chromatography technology 20870941 physical association X 2 Q86YJ5 P07900-2 affinity chromatography technology 22939624 physical association X 2 Q86YJ5 unspecified method 20467438 direct interaction X 2 Q86YJ5 Q86YJ5 in vivo 17174307 - X 2 Q86YJ5 P07339 imaging technique 17174307 colocalization X 2 Q86YJ5 Q86YJ5 anti tag coimmunoprecipitation 17174307 physical association X 2 Q86YJ5 P31016 peptide array 20467438 direct interaction X 2 Q86YJ5 A0A024RD80 luminescence based mammalian interactome mapping 22939624 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B MARCH9 ULBP1 MI:0004(affinity chromatography technology) 20870941 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_201597 prey bait HSP90AA1 MARCH9 MI:0004(affinity chromatography technology) 22939624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_255457 bait prey HSP90AB1 MARCH9 MI:0729(luminescence based mammalian interactome mapping) 22939624 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_125050 prey bait CTSD MARCH9 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 17174307 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization) (intact)|MI:0471(mint)|MI:0471(mint) UniProt_88720|MINT_84887|MINT_52400 neutral component|neutral component|neutral component neutral component|neutral component|neutral component

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q86YJ5 P07900 MARCH9 HSP90AA1 0.126 22939624 Q86YJ5 P07339 MARCH9 CTSD 0.126 17174307 Q86YJ5 P08238 MARCH9 HSP90AB1 0.126 22939624 Q86YJ5 P31016 MARCH9 DLG4 0.183 20467438 Q86YJ5 Q86YJ5 MARCH9 MARCH9 0.236 17174307 Q9BZM6 Q86YJ5 ULBP1 MARCH9 0.21 20870941

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 HSP90AA1 MARCH9 MI:0045 experimental interaction detection MI:0461 interaction database HSP90AB1 MARCH9 MI:0045 experimental interaction detection MI:0461 interaction database DLG4 MARCH9 MI:0362 inference MI:0461 interaction database MARCH9 ULBP1 MI:0045 experimental interaction detection MI:0461 interaction database