Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change BRCA 15 78580711 78580711 + Frame_Shift_Del DEL G G - TCGA-GM-A2DD-01A-11D-A17W-09 TCGA-GM-A2DD-10C-01D-A17W-09 g.chr15:78580711delG c.576delC c.(574-576)cccfs p.P192fs BRCA 15 78585121 78585121 + Missense_Mutation SNP C C G TCGA-D8-A27G-01A-11D-A16D-09 TCGA-D8-A27G-10A-01D-A16D-09 g.chr15:78585121C>G c.156G>C c.(154-156)gaG>gaC p.E52D CESC 15 78577611 78577611 + Nonsense_Mutation SNP G G A TCGA-IR-A3LK-01A-12D-A20U-09 TCGA-IR-A3LK-10A-01D-A20U-09 g.chr15:78577611G>A c.820C>T c.(820-822)Cag>Tag p.Q274* CHOL 15 78580718 78580718 + Missense_Mutation SNP G G T TCGA-W5-AA2Q-01A-11D-A417-09 TCGA-W5-AA2Q-10A-01D-A41A-09 g.chr15:78580718G>T c.569C>A c.(568-570)gCc>gAc p.A190D CHOL 15 78582401 78582401 + Silent SNP A A G TCGA-W5-AA39-01A-11D-A417-09 TCGA-W5-AA39-10A-01D-A41A-09 g.chr15:78582401A>G c.360T>C c.(358-360)taT>taC p.Y120Y COAD 15 78577679 78577679 + Missense_Mutation SNP G G A TCGA-AA-A00N-01A-02W-A00E-09 TCGA-AA-A00N-10A-01W-A00E-09 g.chr15:78577679G>A c.752C>T c.(751-753)tCg>tTg p.S251L COAD 15 78580639 78580639 + Silent SNP G G A TCGA-AA-3555-01A-01W-0831-10 TCGA-AA-3555-10A-01W-0831-10 g.chr15:78580639G>A c.648C>T c.(646-648)atC>atT p.I216I COAD 15 78580688 78580688 + Missense_Mutation SNP G G A TCGA-CM-6162-01A-11D-1650-10 TCGA-CM-6162-10A-01D-1650-10 g.chr15:78580688G>A c.599C>T c.(598-600)cCg>cTg p.P200L COAD 15 78580718 78580718 + Missense_Mutation SNP G G A TCGA-CM-4746-01A-01D-1408-10 TCGA-CM-4746-10A-01D-1408-10 g.chr15:78580718G>A c.569C>T c.(568-570)gCc>gTc p.A190V COAD 15 78581977 78581977 + Silent SNP A A T TCGA-CK-4952-01A-01D-1719-10 TCGA-CK-4952-10A-01D-1719-10 g.chr15:78581977A>T c.546T>A c.(544-546)ctT>ctA p.L182L COAD 15 78585066 78585067 + Missense_Mutation DNP CC CC AA TCGA-AA-3697-01A-01D-1719-10 TCGA-AA-3697-11A-01D-1719-10 g.chr15:78585066_78585067CC>AA c.210_211GG>TT c.(208-213)gtGGac>gtTTac p.D71Y COADREAD 15 78577679 78577679 + Missense_Mutation SNP G G A TCGA-AA-A00N-01A-02W-A00E-09 TCGA-AA-A00N-10A-01W-A00E-09 g.chr15:78577679G>A c.752C>T c.(751-753)tCg>tTg p.S251L COADREAD 15 78580639 78580639 + Silent SNP G G A TCGA-AA-3555-01A-01W-0831-10 TCGA-AA-3555-10A-01W-0831-10 g.chr15:78580639G>A c.648C>T c.(646-648)atC>atT p.I216I COADREAD 15 78580688 78580688 + Missense_Mutation SNP G G A TCGA-CM-6162-01A-11D-1650-10 TCGA-CM-6162-10A-01D-1650-10 g.chr15:78580688G>A c.599C>T c.(598-600)cCg>cTg p.P200L COADREAD 15 78580718 78580718 + Missense_Mutation SNP G G A TCGA-CM-4746-01A-01D-1408-10 TCGA-CM-4746-10A-01D-1408-10 g.chr15:78580718G>A c.569C>T c.(568-570)gCc>gTc p.A190V COADREAD 15 78581977 78581977 + Silent SNP A A T TCGA-CK-4952-01A-01D-1719-10 TCGA-CK-4952-10A-01D-1719-10 g.chr15:78581977A>T c.546T>A c.(544-546)ctT>ctA p.L182L COADREAD 15 78581978 78581978 + Missense_Mutation SNP A A G TCGA-F5-6465-01A-11D-1733-10 TCGA-F5-6465-10A-01D-1733-10 g.chr15:78581978A>G c.545T>C c.(544-546)cTt>cCt p.L182P COADREAD 15 78585066 78585067 + Missense_Mutation DNP CC CC AA TCGA-AA-3697-01A-01D-1719-10 TCGA-AA-3697-11A-01D-1719-10 g.chr15:78585066_78585067CC>AA c.210_211GG>TT c.(208-213)gtGGac>gtTTac p.D71Y ESCA 15 78580699 78580699 + Missense_Mutation SNP C C G TCGA-IG-A51D-01A-11D-A27G-09 TCGA-IG-A51D-10A-01D-A27G-09 g.chr15:78580699C>G c.588G>C c.(586-588)ttG>ttC p.L196F GBM 15 78578420 78578420 + Missense_Mutation SNP C C T TCGA-06-5858-01A-01D-1696-08 TCGA-06-5858-10A-01D-1696-08 g.chr15:78578420C>T c.712G>A c.(712-714)Gtt>Att p.V238I GBMLGG 15 78578420 78578420 + Missense_Mutation SNP C C T TCGA-06-5858-01A-01D-1696-08 TCGA-06-5858-10A-01D-1696-08 g.chr15:78578420C>T c.712G>A c.(712-714)Gtt>Att p.V238I LIHC 15 78582307 78582307 + Missense_Mutation SNP G G C TCGA-DD-AACZ-01A-11D-A40R-10 TCGA-DD-AACZ-10A-01D-A40U-10 g.chr15:78582307G>C c.454C>G c.(454-456)Ctt>Gtt p.L152V LUAD 15 78577629 78577629 + Missense_Mutation SNP G G A TCGA-44-7670-01A-11D-2063-08 TCGA-44-7670-10A-01D-2063-08 g.chr15:78577629G>A c.802C>T c.(802-804)Cac>Tac p.H268Y LUAD 15 78585583 78585583 + Missense_Mutation SNP C C A TCGA-95-7043-01A-11D-1945-08 TCGA-95-7043-10A-01D-1946-08 g.chr15:78585583C>A c.72G>T c.(70-72)tgG>tgT p.W24C OV 15 78575864 78575864 + Splice_Site SNP C C T TCGA-61-1895-01A-01W-0639-09 TCGA-61-1895-11A-01W-0639-09 g.chr15:78575864C>T c.e11-1 OV 15 78581979 78581979 + Missense_Mutation SNP G G A TCGA-13-0755-01A-01W-0372-09 TCGA-13-0755-10A-01W-0372-09 g.chr15:78581979G>A c.544C>T c.(544-546)Ctt>Ttt p.L182F PAAD 15 78585111 78585111 + Missense_Mutation SNP G G T TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr15:78585111G>T c.166C>A c.(166-168)Cta>Ata p.L56I READ 15 78581978 78581978 + Missense_Mutation SNP A A G TCGA-F5-6465-01A-11D-1733-10 TCGA-F5-6465-10A-01D-1733-10 g.chr15:78581978A>G c.545T>C c.(544-546)cTt>cCt p.L182P SKCM 15 78580681 78580681 + Silent SNP G G A TCGA-EE-A2MH-06A-11D-A197-08 TCGA-EE-A2MH-10A-01D-A199-08 g.chr15:78580681G>A c.606C>T c.(604-606)tcC>tcT p.S202S

Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-US 15 78566699 78566699 single base substitution C T downstream_gene_variant BOCA-FR 15 78580095 78580095 single base substitution T C downstream_gene_variant BOCA-FR 15 78580095 78580095 single base substitution T C intron_variant BOCA-FR 15 78580095 78580095 single base substitution T C upstream_gene_variant BRCA-EU 15 78566051 78566051 single base substitution C T downstream_gene_variant BRCA-EU 15 78566690 78566690 single base substitution C T downstream_gene_variant BRCA-EU 15 78570223 78570223 single base substitution C T 3_prime_UTR_variant BRCA-EU 15 78570700 78570700 single base substitution T C downstream_gene_variant BRCA-EU 15 78570700 78570700 single base substitution T C intron_variant BRCA-EU 15 78572358 78572363 multiple base substitution (>=2bp and <=200bp) TCCTTC TG downstream_gene_variant BRCA-EU 15 78572358 78572363 multiple base substitution (>=2bp and <=200bp) TCCTTC TG intron_variant BRCA-EU 15 78572730 78572730 single base substitution G A downstream_gene_variant BRCA-EU 15 78572730 78572730 single base substitution G A intron_variant BRCA-EU 15 78574349 78574349 single base substitution C G downstream_gene_variant BRCA-EU 15 78574349 78574349 single base substitution C G intron_variant BRCA-EU 15 78575218 78575218 single base substitution G A downstream_gene_variant BRCA-EU 15 78575218 78575218 single base substitution G A intron_variant BRCA-EU 15 78577434 78577434 single base substitution A C downstream_gene_variant BRCA-EU 15 78577434 78577434 single base substitution A C exon_variant BRCA-EU 15 78577434 78577434 single base substitution A C intron_variant BRCA-EU 15 78578176 78578176 single base substitution A G downstream_gene_variant BRCA-EU 15 78578176 78578176 single base substitution A G exon_variant BRCA-EU 15 78578176 78578176 single base substitution A G intron_variant BRCA-EU 15 78579821 78579821 single base substitution C G downstream_gene_variant BRCA-EU 15 78579821 78579821 single base substitution C G intron_variant BRCA-EU 15 78579821 78579821 single base substitution C G upstream_gene_variant BRCA-EU 15 78580463 78580463 single base substitution C T downstream_gene_variant BRCA-EU 15 78580463 78580463 single base substitution C T intron_variant BRCA-EU 15 78580463 78580463 single base substitution C T upstream_gene_variant BRCA-EU 15 78582010 78582010 single base substitution G T 3_prime_UTR_variant BRCA-EU 15 78582010 78582010 single base substitution G T downstream_gene_variant BRCA-EU 15 78582010 78582010 single base substitution G T exon_variant BRCA-EU 15 78582010 78582010 single base substitution G T synonymous_variant I171I 513C>A BRCA-EU 15 78582010 78582010 single base substitution G T synonymous_variant I41I 123C>A BRCA-EU 15 78582010 78582010 single base substitution G T synonymous_variant I78I 234C>A BRCA-EU 15 78582010 78582010 single base substitution G T upstream_gene_variant BRCA-EU 15 78582011 78582011 single base substitution A T 3_prime_UTR_variant BRCA-EU 15 78582011 78582011 single base substitution A T downstream_gene_variant BRCA-EU 15 78582011 78582011 single base substitution A T exon_variant BRCA-EU 15 78582011 78582011 single base substitution A T missense_variant I171N 512T>A BRCA-EU 15 78582011 78582011 single base substitution A T missense_variant I41N 122T>A BRCA-EU 15 78582011 78582011 single base substitution A T missense_variant I78N 233T>A BRCA-EU 15 78582011 78582011 single base substitution A T upstream_gene_variant BRCA-EU 15 78582880 78582880 single base substitution C G downstream_gene_variant BRCA-EU 15 78582880 78582880 single base substitution C G intron_variant BRCA-EU 15 78582880 78582880 single base substitution C G upstream_gene_variant BRCA-EU 15 78583176 78583176 single base substitution G A downstream_gene_variant BRCA-EU 15 78583176 78583176 single base substitution G A intron_variant BRCA-EU 15 78583176 78583176 single base substitution G A upstream_gene_variant BRCA-EU 15 78584338 78584338 single base substitution T G downstream_gene_variant BRCA-EU 15 78584338 78584338 single base substitution T G exon_variant BRCA-EU 15 78584338 78584338 single base substitution T G intron_variant BRCA-EU 15 78584338 78584338 single base substitution T G upstream_gene_variant BRCA-EU 15 78584485 78584485 single base substitution G A downstream_gene_variant BRCA-EU 15 78584485 78584485 single base substitution G A exon_variant BRCA-EU 15 78584485 78584485 single base substitution G A intron_variant BRCA-EU 15 78584485 78584485 single base substitution G A upstream_gene_variant BRCA-EU 15 78584507 78584507 single base substitution A G downstream_gene_variant BRCA-EU 15 78584507 78584507 single base substitution A G exon_variant BRCA-EU 15 78584507 78584507 single base substitution A G intron_variant BRCA-EU 15 78584507 78584507 single base substitution A G upstream_gene_variant BRCA-EU 15 78585382 78585386 deletion of <=200bp ATACC - downstream_gene_variant BRCA-EU 15 78585382 78585386 deletion of <=200bp ATACC - intron_variant BRCA-EU 15 78585382 78585386 deletion of <=200bp ATACC - upstream_gene_variant BRCA-EU 15 78588581 78588581 single base substitution C G intron_variant BRCA-EU 15 78588774 78588774 single base substitution A T intron_variant BRCA-EU 15 78590503 78590503 single base substitution C A intron_variant BRCA-EU 15 78591396 78591396 single base substitution G T intron_variant BRCA-EU 15 78591930 78591930 single base substitution A G 5_prime_UTR_variant BRCA-EU 15 78591930 78591930 single base substitution A G exon_variant BRCA-EU 15 78591930 78591930 single base substitution A G upstream_gene_variant BRCA-EU 15 78593097 78593097 single base substitution G C upstream_gene_variant BRCA-EU 15 78593226 78593226 single base substitution G A upstream_gene_variant BRCA-EU 15 78594352 78594352 insertion of <=200bp - T upstream_gene_variant BRCA-FR 15 78570223 78570223 single base substitution C T 3_prime_UTR_variant BRCA-FR 15 78571186 78571186 single base substitution T G downstream_gene_variant BRCA-FR 15 78571186 78571186 single base substitution T G intron_variant BRCA-FR 15 78572626 78572626 single base substitution C T downstream_gene_variant BRCA-FR 15 78572626 78572626 single base substitution C T intron_variant BRCA-FR 15 78577434 78577434 single base substitution A C downstream_gene_variant BRCA-FR 15 78577434 78577434 single base substitution A C exon_variant BRCA-FR 15 78577434 78577434 single base substitution A C intron_variant BRCA-FR 15 78583184 78583184 single base substitution C T downstream_gene_variant BRCA-FR 15 78583184 78583184 single base substitution C T intron_variant BRCA-FR 15 78583184 78583184 single base substitution C T upstream_gene_variant BRCA-FR 15 78584338 78584338 single base substitution T G downstream_gene_variant BRCA-FR 15 78584338 78584338 single base substitution T G exon_variant BRCA-FR 15 78584338 78584338 single base substitution T G intron_variant BRCA-FR 15 78584338 78584338 single base substitution T G upstream_gene_variant BRCA-FR 15 78590503 78590503 single base substitution C A intron_variant BRCA-UK 15 78575218 78575218 single base substitution G A downstream_gene_variant BRCA-UK 15 78575218 78575218 single base substitution G A intron_variant BRCA-US 15 78566657 78566657 single base substitution C T downstream_gene_variant BRCA-US 15 78568072 78568072 single base substitution T C downstream_gene_variant BRCA-US 15 78572663 78572666 deletion of <=200bp AAGT - downstream_gene_variant BRCA-US 15 78572663 78572666 deletion of <=200bp AAGT - intron_variant BRCA-US 15 78580711 78580711 deletion of <=200bp G - 3_prime_UTR_variant BRCA-US 15 78580711 78580711 deletion of <=200bp G - downstream_gene_variant BRCA-US 15 78580711 78580711 deletion of <=200bp G - frameshift_variant P11 BRCA-US 15 78580711 78580711 deletion of <=200bp G - frameshift_variant P192 BRCA-US 15 78580711 78580711 deletion of <=200bp G - frameshift_variant P62 BRCA-US 15 78580711 78580711 deletion of <=200bp G - frameshift_variant P99 BRCA-US 15 78580711 78580711 deletion of <=200bp G - upstream_gene_variant BRCA-US 15 78585121 78585121 single base substitution C G 3_prime_UTR_variant BRCA-US 15 78585121 78585121 single base substitution C G downstream_gene_variant BRCA-US 15 78585121 78585121 single base substitution C G exon_variant BRCA-US 15 78585121 78585121 single base substitution C G intron_variant BRCA-US 15 78585121 78585121 single base substitution C G missense_variant E52D 156G>C BRCA-US 15 78585121 78585121 single base substitution C G upstream_gene_variant BTCA-JP 15 78565414 78565414 single base substitution A G downstream_gene_variant BTCA-JP 15 78570462 78570462 single base substitution T C intron_variant BTCA-JP 15 78572811 78572811 single base substitution G A downstream_gene_variant BTCA-JP 15 78572811 78572811 single base substitution G A intron_variant BTCA-JP 15 78581212 78581212 single base substitution T C 3_prime_UTR_variant BTCA-JP 15 78581212 78581212 single base substitution T C downstream_gene_variant BTCA-JP 15 78581212 78581212 single base substitution T C intron_variant BTCA-JP 15 78581212 78581212 single base substitution T C upstream_gene_variant BTCA-JP 15 78582363 78582363 single base substitution A G 3_prime_UTR_variant BTCA-JP 15 78582363 78582363 single base substitution A G downstream_gene_variant BTCA-JP 15 78582363 78582363 single base substitution A G exon_variant BTCA-JP 15 78582363 78582363 single base substitution A G missense_variant F133S 398T>C BTCA-JP 15 78582363 78582363 single base substitution A G missense_variant F3S 8T>C BTCA-JP 15 78582363 78582363 single base substitution A G missense_variant F40S 119T>C BTCA-JP 15 78582363 78582363 single base substitution A G upstream_gene_variant CESC-US 15 78577611 78577611 single base substitution G A downstream_gene_variant CESC-US 15 78577611 78577611 single base substitution G A exon_variant CESC-US 15 78577611 78577611 single base substitution G A intron_variant CESC-US 15 78577611 78577611 single base substitution G A stop_gained Q144* 430C>T CESC-US 15 78577611 78577611 single base substitution G A stop_gained Q181* 541C>T CESC-US 15 78577611 78577611 single base substitution G A stop_gained Q274* 820C>T CLLE-ES 15 78565665 78565665 single base substitution C A downstream_gene_variant CLLE-ES 15 78570505 78570505 single base substitution T G intron_variant CLLE-ES 15 78583654 78583654 single base substitution G T downstream_gene_variant CLLE-ES 15 78583654 78583654 single base substitution G T intron_variant CLLE-ES 15 78583654 78583654 single base substitution G T upstream_gene_variant CLLE-ES 15 78591497 78591497 single base substitution G C intron_variant COAD-US 15 78566575 78566575 single base substitution C T downstream_gene_variant COAD-US 15 78566734 78566736 deletion of <=200bp AGA - downstream_gene_variant COAD-US 15 78567853 78567853 single base substitution G T downstream_gene_variant COAD-US 15 78568023 78568023 single base substitution C T downstream_gene_variant COAD-US 15 78568044 78568044 single base substitution G A downstream_gene_variant COAD-US 15 78580688 78580688 single base substitution G A 3_prime_UTR_variant COAD-US 15 78580688 78580688 single base substitution G A downstream_gene_variant COAD-US 15 78580688 78580688 single base substitution G A missense_variant P107L 320C>T COAD-US 15 78580688 78580688 single base substitution G A missense_variant P19L 56C>T COAD-US 15 78580688 78580688 single base substitution G A missense_variant P200L 599C>T COAD-US 15 78580688 78580688 single base substitution G A missense_variant P70L 209C>T COAD-US 15 78580688 78580688 single base substitution G A upstream_gene_variant COAD-US 15 78580718 78580718 single base substitution G A 3_prime_UTR_variant COAD-US 15 78580718 78580718 single base substitution G A downstream_gene_variant COAD-US 15 78580718 78580718 single base substitution G A missense_variant A190V 569C>T COAD-US 15 78580718 78580718 single base substitution G A missense_variant A60V 179C>T COAD-US 15 78580718 78580718 single base substitution G A missense_variant A97V 290C>T COAD-US 15 78580718 78580718 single base substitution G A missense_variant A9V 26C>T COAD-US 15 78580718 78580718 single base substitution G A upstream_gene_variant COAD-US 15 78582397 78582397 single base substitution C T 3_prime_UTR_variant COAD-US 15 78582397 78582397 single base substitution C T downstream_gene_variant COAD-US 15 78582397 78582397 single base substitution C T exon_variant COAD-US 15 78582397 78582397 single base substitution C T missense_variant A122T 364G>A COAD-US 15 78582397 78582397 single base substitution C T missense_variant A29T 85G>A COAD-US 15 78582397 78582397 single base substitution C T upstream_gene_variant COAD-US 15 78585066 78585066 single base substitution C A 3_prime_UTR_variant COAD-US 15 78585066 78585066 single base substitution C A downstream_gene_variant COAD-US 15 78585066 78585066 single base substitution C A exon_variant COAD-US 15 78585066 78585066 single base substitution C A intron_variant COAD-US 15 78585066 78585066 single base substitution C A missense_variant D71Y 211G>T COAD-US 15 78585066 78585066 single base substitution C A upstream_gene_variant COAD-US 15 78585067 78585067 single base substitution C A 3_prime_UTR_variant COAD-US 15 78585067 78585067 single base substitution C A downstream_gene_variant COAD-US 15 78585067 78585067 single base substitution C A exon_variant COAD-US 15 78585067 78585067 single base substitution C A intron_variant COAD-US 15 78585067 78585067 single base substitution C A synonymous_variant V70V 210G>T COAD-US 15 78585067 78585067 single base substitution C A upstream_gene_variant COCA-CN 15 78572760 78572760 single base substitution C T downstream_gene_variant COCA-CN 15 78572760 78572760 single base substitution C T intron_variant COCA-CN 15 78577709 78577709 single base substitution G A downstream_gene_variant COCA-CN 15 78577709 78577709 single base substitution G A exon_variant COCA-CN 15 78577709 78577709 single base substitution G A intron_variant COCA-CN 15 78578485 78578485 single base substitution G A downstream_gene_variant COCA-CN 15 78578485 78578485 single base substitution G A exon_variant COCA-CN 15 78578485 78578485 single base substitution G A intron_variant COCA-CN 15 78578485 78578485 single base substitution G A upstream_gene_variant COCA-CN 15 78581840 78581840 single base substitution T C downstream_gene_variant COCA-CN 15 78581840 78581840 single base substitution T C intron_variant COCA-CN 15 78581840 78581840 single base substitution T C upstream_gene_variant COCA-CN 15 78582308 78582308 single base substitution A G 3_prime_UTR_variant COCA-CN 15 78582308 78582308 single base substitution A G downstream_gene_variant COCA-CN 15 78582308 78582308 single base substitution A G exon_variant COCA-CN 15 78582308 78582308 single base substitution A G synonymous_variant I151I 453T>C COCA-CN 15 78582308 78582308 single base substitution A G synonymous_variant I21I 63T>C COCA-CN 15 78582308 78582308 single base substitution A G synonymous_variant I58I 174T>C COCA-CN 15 78582308 78582308 single base substitution A G upstream_gene_variant EOPC-DE 15 78572077 78572077 single base substitution G A downstream_gene_variant EOPC-DE 15 78572077 78572077 single base substitution G A intron_variant ESAD-UK 15 78565408 78565408 single base substitution G A downstream_gene_variant ESAD-UK 15 78566262 78566262 single base substitution C T downstream_gene_variant ESAD-UK 15 78566383 78566383 single base substitution C T downstream_gene_variant ESAD-UK 15 78570178 78570178 single base substitution C T 3_prime_UTR_variant ESAD-UK 15 78572060 78572060 single base substitution G A downstream_gene_variant ESAD-UK 15 78572060 78572060 single base substitution G A intron_variant ESAD-UK 15 78573472 78573472 single base substitution C T downstream_gene_variant ESAD-UK 15 78573472 78573472 single base substitution C T intron_variant ESAD-UK 15 78576294 78576294 single base substitution C T downstream_gene_variant ESAD-UK 15 78576294 78576294 single base substitution C T exon_variant ESAD-UK 15 78576294 78576294 single base substitution C T intron_variant ESAD-UK 15 78578877 78578877 single base substitution C T downstream_gene_variant ESAD-UK 15 78578877 78578877 single base substitution C T exon_variant ESAD-UK 15 78578877 78578877 single base substitution C T intron_variant ESAD-UK 15 78578877 78578877 single base substitution C T upstream_gene_variant ESAD-UK 15 78579133 78579133 single base substitution G A downstream_gene_variant ESAD-UK 15 78579133 78579133 single base substitution G A exon_variant ESAD-UK 15 78579133 78579133 single base substitution G A intron_variant ESAD-UK 15 78579133 78579133 single base substitution G A upstream_gene_variant ESAD-UK 15 78580169 78580169 single base substitution C T downstream_gene_variant ESAD-UK 15 78580169 78580169 single base substitution C T intron_variant ESAD-UK 15 78580169 78580169 single base substitution C T upstream_gene_variant ESAD-UK 15 78584926 78584926 single base substitution T G downstream_gene_variant ESAD-UK 15 78584926 78584926 single base substitution T G exon_variant ESAD-UK 15 78584926 78584926 single base substitution T G intron_variant ESAD-UK 15 78584926 78584926 single base substitution T G upstream_gene_variant ESAD-UK 15 78586116 78586116 single base substitution T C downstream_gene_variant ESAD-UK 15 78586116 78586116 single base substitution T C intron_variant ESAD-UK 15 78586116 78586116 single base substitution T C upstream_gene_variant ESAD-UK 15 78588467 78588467 single base substitution C T intron_variant ESAD-UK 15 78590158 78590158 single base substitution C A intron_variant ESAD-UK 15 78591159 78591159 single base substitution T A intron_variant ESAD-UK 15 78591387 78591387 single base substitution T G intron_variant ESAD-UK 15 78592249 78592249 single base substitution A T upstream_gene_variant ESAD-UK 15 78592794 78592794 single base substitution A G upstream_gene_variant ESAD-UK 15 78593341 78593341 single base substitution T G upstream_gene_variant ESAD-UK 15 78593345 78593345 single base substitution G T upstream_gene_variant ESAD-UK 15 78593676 78593676 single base substitution G T upstream_gene_variant ESAD-UK 15 78594096 78594096 single base substitution T C upstream_gene_variant ESAD-UK 15 78594222 78594222 single base substitution G A upstream_gene_variant ESAD-UK 15 78594537 78594537 single base substitution G A upstream_gene_variant ESAD-UK 15 78596801 78596801 single base substitution A T upstream_gene_variant ESCA-CN 15 78567973 78567973 single base substitution C A downstream_gene_variant ESCA-CN 15 78581840 78581840 single base substitution T C downstream_gene_variant ESCA-CN 15 78581840 78581840 single base substitution T C intron_variant ESCA-CN 15 78581840 78581840 single base substitution T C upstream_gene_variant ESCA-CN 15 78582018 78582018 single base substitution C T 3_prime_UTR_variant ESCA-CN 15 78582018 78582018 single base substitution C T downstream_gene_variant ESCA-CN 15 78582018 78582018 single base substitution C T exon_variant ESCA-CN 15 78582018 78582018 single base substitution C T missense_variant D169N 505G>A ESCA-CN 15 78582018 78582018 single base substitution C T missense_variant D39N 115G>A ESCA-CN 15 78582018 78582018 single base substitution C T missense_variant D76N 226G>A ESCA-CN 15 78582018 78582018 single base substitution C T upstream_gene_variant GBM-US 15 78567950 78567950 single base substitution C G downstream_gene_variant GBM-US 15 78578420 78578420 single base substitution C T downstream_gene_variant GBM-US 15 78578420 78578420 single base substitution C T exon_variant GBM-US 15 78578420 78578420 single base substitution C T intron_variant GBM-US 15 78578420 78578420 single base substitution C T missense_variant V108I 322G>A GBM-US 15 78578420 78578420 single base substitution C T missense_variant V145I 433G>A GBM-US 15 78578420 78578420 single base substitution C T missense_variant V238I 712G>A GBM-US 15 78578420 78578420 single base substitution C T upstream_gene_variant KIRC-US 15 78565450 78565450 single base substitution A G downstream_gene_variant LAML-KR 15 78592554 78592554 single base substitution A G upstream_gene_variant LICA-FR 15 78571806 78571806 single base substitution C A downstream_gene_variant LICA-FR 15 78571806 78571806 single base substitution C A intron_variant LICA-FR 15 78577281 78577281 single base substitution C A downstream_gene_variant LICA-FR 15 78577281 78577281 single base substitution C A exon_variant LICA-FR 15 78577281 78577281 single base substitution C A intron_variant LICA-FR 15 78583438 78583438 single base substitution T C downstream_gene_variant LICA-FR 15 78583438 78583438 single base substitution T C intron_variant LICA-FR 15 78583438 78583438 single base substitution T C upstream_gene_variant LICA-FR 15 78586099 78586099 single base substitution A T downstream_gene_variant LICA-FR 15 78586099 78586099 single base substitution A T intron_variant LICA-FR 15 78586099 78586099 single base substitution A T upstream_gene_variant LICA-FR 15 78592775 78592775 insertion of <=200bp - A upstream_gene_variant LICA-FR 15 78595379 78595379 single base substitution A T upstream_gene_variant LINC-JP 15 78570669 78570669 single base substitution A G downstream_gene_variant LINC-JP 15 78570669 78570669 single base substitution A G intron_variant LINC-JP 15 78570732 78570732 single base substitution T C downstream_gene_variant LINC-JP 15 78570732 78570732 single base substitution T C intron_variant LINC-JP 15 78572139 78572139 single base substitution C T downstream_gene_variant LINC-JP 15 78572139 78572139 single base substitution C T intron_variant LINC-JP 15 78575024 78575024 single base substitution T A downstream_gene_variant LINC-JP 15 78575024 78575024 single base substitution T A intron_variant LINC-JP 15 78583170 78583170 single base substitution G T downstream_gene_variant LINC-JP 15 78583170 78583170 single base substitution G T intron_variant LINC-JP 15 78583170 78583170 single base substitution G T upstream_gene_variant LINC-JP 15 78586633 78586633 single base substitution C T downstream_gene_variant LINC-JP 15 78586633 78586633 single base substitution C T intron_variant LINC-JP 15 78586633 78586633 single base substitution C T upstream_gene_variant LINC-JP 15 78587217 78587217 single base substitution A G exon_variant LINC-JP 15 78587217 78587217 single base substitution A G intron_variant LINC-JP 15 78587217 78587217 single base substitution A G upstream_gene_variant LINC-JP 15 78587761 78587761 single base substitution G T exon_variant LINC-JP 15 78587761 78587761 single base substitution G T intron_variant LIRI-JP 15 78567037 78567037 single base substitution A G downstream_gene_variant LIRI-JP 15 78567241 78567241 single base substitution T C downstream_gene_variant LIRI-JP 15 78569044 78569044 single base substitution C A downstream_gene_variant LIRI-JP 15 78570223 78570223 single base substitution C G 3_prime_UTR_variant LIRI-JP 15 78575171 78575171 single base substitution T C downstream_gene_variant LIRI-JP 15 78575171 78575171 single base substitution T C intron_variant LIRI-JP 15 78582331 78582331 single base substitution A G 3_prime_UTR_variant LIRI-JP 15 78582331 78582331 single base substitution A G downstream_gene_variant LIRI-JP 15 78582331 78582331 single base substitution A G exon_variant LIRI-JP 15 78582331 78582331 single base substitution A G synonymous_variant L144L 430T>C LIRI-JP 15 78582331 78582331 single base substitution A G synonymous_variant L14L 40T>C LIRI-JP 15 78582331 78582331 single base substitution A G synonymous_variant L51L 151T>C LIRI-JP 15 78582331 78582331 single base substitution A G upstream_gene_variant LIRI-JP 15 78582394 78582394 single base substitution T C 3_prime_UTR_variant LIRI-JP 15 78582394 78582394 single base substitution T C downstream_gene_variant LIRI-JP 15 78582394 78582394 single base substitution T C exon_variant LIRI-JP 15 78582394 78582394 single base substitution T C missense_variant T123A 367A>G LIRI-JP 15 78582394 78582394 single base substitution T C missense_variant T30A 88A>G LIRI-JP 15 78582394 78582394 single base substitution T C upstream_gene_variant LIRI-JP 15 78583008 78583008 single base substitution A T downstream_gene_variant LIRI-JP 15 78583008 78583008 single base substitution A T intron_variant LIRI-JP 15 78583008 78583008 single base substitution A T upstream_gene_variant LIRI-JP 15 78584925 78584925 single base substitution C T downstream_gene_variant LIRI-JP 15 78584925 78584925 single base substitution C T exon_variant LIRI-JP 15 78584925 78584925 single base substitution C T intron_variant LIRI-JP 15 78584925 78584925 single base substitution C T upstream_gene_variant LIRI-JP 15 78586179 78586179 single base substitution G A downstream_gene_variant LIRI-JP 15 78586179 78586179 single base substitution G A intron_variant LIRI-JP 15 78586179 78586179 single base substitution G A upstream_gene_variant LIRI-JP 15 78587954 78587954 single base substitution C G exon_variant LIRI-JP 15 78587954 78587954 single base substitution C G intron_variant LIRI-JP 15 78589336 78589336 single base substitution A T intron_variant LIRI-JP 15 78591412 78591412 single base substitution G A intron_variant LIRI-JP 15 78592173 78592173 single base substitution G T upstream_gene_variant LIRI-JP 15 78592182 78592182 single base substitution G C upstream_gene_variant LIRI-JP 15 78594678 78594678 single base substitution C G upstream_gene_variant LIRI-JP 15 78594795 78594795 single base substitution G A upstream_gene_variant LUSC-KR 15 78565478 78565478 single base substitution C T downstream_gene_variant LUSC-KR 15 78565616 78565616 single base substitution A G downstream_gene_variant LUSC-KR 15 78565804 78565804 single base substitution G C downstream_gene_variant LUSC-KR 15 78566840 78566840 single base substitution C G downstream_gene_variant LUSC-KR 15 78568525 78568525 single base substitution T G downstream_gene_variant LUSC-KR 15 78573745 78573745 single base substitution G C downstream_gene_variant LUSC-KR 15 78573745 78573745 single base substitution G C intron_variant LUSC-KR 15 78573976 78573976 single base substitution G T downstream_gene_variant LUSC-KR 15 78573976 78573976 single base substitution G T intron_variant LUSC-KR 15 78579280 78579280 single base substitution G A downstream_gene_variant LUSC-KR 15 78579280 78579280 single base substitution G A intron_variant LUSC-KR 15 78579280 78579280 single base substitution G A upstream_gene_variant LUSC-KR 15 78589817 78589817 single base substitution C G intron_variant MALY-DE 15 78583303 78583303 single base substitution A T downstream_gene_variant MALY-DE 15 78583303 78583303 single base substitution A T intron_variant MALY-DE 15 78583303 78583303 single base substitution A T upstream_gene_variant MALY-DE 15 78593343 78593343 single base substitution G T upstream_gene_variant MALY-DE 15 78594526 78594526 single base substitution T G upstream_gene_variant MELA-AU 15 78565899 78565899 single base substitution G T downstream_gene_variant MELA-AU 15 78566549 78566549 single base substitution G A downstream_gene_variant MELA-AU 15 78570398 78570398 single base substitution C T 3_prime_UTR_variant MELA-AU 15 78572205 78572205 single base substitution C T downstream_gene_variant MELA-AU 15 78572205 78572205 single base substitution C T intron_variant MELA-AU 15 78573617 78573617 single base substitution C A downstream_gene_variant MELA-AU 15 78573617 78573617 single base substitution C A intron_variant MELA-AU 15 78574437 78574437 single base substitution C T downstream_gene_variant MELA-AU 15 78574437 78574437 single base substitution C T intron_variant MELA-AU 15 78574615 78574615 single base substitution G T downstream_gene_variant MELA-AU 15 78574615 78574615 single base substitution G T intron_variant MELA-AU 15 78574628 78574628 single base substitution G T downstream_gene_variant MELA-AU 15 78574628 78574628 single base substitution G T intron_variant MELA-AU 15 78576711 78576711 single base substitution G A downstream_gene_variant MELA-AU 15 78576711 78576711 single base substitution G A exon_variant MELA-AU 15 78576711 78576711 single base substitution G A intron_variant MELA-AU 15 78578193 78578193 single base substitution G A downstream_gene_variant MELA-AU 15 78578193 78578193 single base substitution G A exon_variant MELA-AU 15 78578193 78578193 single base substitution G A intron_variant MELA-AU 15 78578774 78578774 single base substitution C T downstream_gene_variant MELA-AU 15 78578774 78578774 single base substitution C T exon_variant MELA-AU 15 78578774 78578774 single base substitution C T intron_variant MELA-AU 15 78578774 78578774 single base substitution C T upstream_gene_variant MELA-AU 15 78578872 78578872 single base substitution C T downstream_gene_variant MELA-AU 15 78578872 78578872 single base substitution C T exon_variant MELA-AU 15 78578872 78578872 single base substitution C T intron_variant MELA-AU 15 78578872 78578872 single base substitution C T upstream_gene_variant MELA-AU 15 78579466 78579466 single base substitution G A downstream_gene_variant MELA-AU 15 78579466 78579466 single base substitution G A intron_variant MELA-AU 15 78579466 78579466 single base substitution G A upstream_gene_variant MELA-AU 15 78579580 78579580 single base substitution C T downstream_gene_variant MELA-AU 15 78579580 78579580 single base substitution C T intron_variant MELA-AU 15 78579580 78579580 single base substitution C T upstream_gene_variant MELA-AU 15 78579952 78579952 single base substitution G C downstream_gene_variant MELA-AU 15 78579952 78579952 single base substitution G C intron_variant MELA-AU 15 78579952 78579952 single base substitution G C upstream_gene_variant MELA-AU 15 78580492 78580492 single base substitution G A downstream_gene_variant MELA-AU 15 78580492 78580492 single base substitution G A intron_variant MELA-AU 15 78580492 78580492 single base substitution G A upstream_gene_variant MELA-AU 15 78580681 78580681 single base substitution G A 3_prime_UTR_variant MELA-AU 15 78580681 78580681 single base substitution G A downstream_gene_variant MELA-AU 15 78580681 78580681 single base substitution G A synonymous_variant S109S 327C>T MELA-AU 15 78580681 78580681 single base substitution G A synonymous_variant S202S 606C>T MELA-AU 15 78580681 78580681 single base substitution G A synonymous_variant S21S 63C>T MELA-AU 15 78580681 78580681 single base substitution G A synonymous_variant S72S 216C>T MELA-AU 15 78580681 78580681 single base substitution G A upstream_gene_variant MELA-AU 15 78580857 78580857 single base substitution G A downstream_gene_variant MELA-AU 15 78580857 78580857 single base substitution G A intron_variant MELA-AU 15 78580857 78580857 single base substitution G A upstream_gene_variant MELA-AU 15 78582377 78582377 single base substitution C G 3_prime_UTR_variant MELA-AU 15 78582377 78582377 single base substitution C G downstream_gene_variant MELA-AU 15 78582377 78582377 single base substitution C G exon_variant MELA-AU 15 78582377 78582377 single base substitution C G synonymous_variant G128G 384G>C MELA-AU 15 78582377 78582377 single base substitution C G synonymous_variant G35G 105G>C MELA-AU 15 78582377 78582377 single base substitution C G upstream_gene_variant MELA-AU 15 78582538 78582538 single base substitution G A downstream_gene_variant MELA-AU 15 78582538 78582538 single base substitution G A intron_variant MELA-AU 15 78582538 78582538 single base substitution G A upstream_gene_variant MELA-AU 15 78582820 78582820 single base substitution G A downstream_gene_variant MELA-AU 15 78582820 78582820 single base substitution G A intron_variant MELA-AU 15 78582820 78582820 single base substitution G A upstream_gene_variant MELA-AU 15 78582869 78582870 multiple base substitution (>=2bp and <=200bp) GG AA downstream_gene_variant MELA-AU 15 78582869 78582870 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 15 78582869 78582870 multiple base substitution (>=2bp and <=200bp) GG AA upstream_gene_variant MELA-AU 15 78583425 78583425 single base substitution T A downstream_gene_variant MELA-AU 15 78583425 78583425 single base substitution T A intron_variant MELA-AU 15 78583425 78583425 single base substitution T A upstream_gene_variant MELA-AU 15 78584041 78584041 single base substitution G A downstream_gene_variant MELA-AU 15 78584041 78584041 single base substitution G A intron_variant MELA-AU 15 78584041 78584041 single base substitution G A upstream_gene_variant MELA-AU 15 78584156 78584156 single base substitution G A downstream_gene_variant MELA-AU 15 78584156 78584156 single base substitution G A exon_variant MELA-AU 15 78584156 78584156 single base substitution G A intron_variant MELA-AU 15 78584156 78584156 single base substitution G A upstream_gene_variant MELA-AU 15 78584501 78584501 single base substitution G A downstream_gene_variant MELA-AU 15 78584501 78584501 single base substitution G A exon_variant MELA-AU 15 78584501 78584501 single base substitution G A intron_variant MELA-AU 15 78584501 78584501 single base substitution G A upstream_gene_variant MELA-AU 15 78585094 78585094 single base substitution C T 3_prime_UTR_variant MELA-AU 15 78585094 78585094 single base substitution C T downstream_gene_variant MELA-AU 15 78585094 78585094 single base substitution C T exon_variant MELA-AU 15 78585094 78585094 single base substitution C T intron_variant MELA-AU 15 78585094 78585094 single base substitution C T synonymous_variant E61E 183G>A MELA-AU 15 78585094 78585094 single base substitution C T upstream_gene_variant MELA-AU 15 78585859 78585859 single base substitution A G downstream_gene_variant MELA-AU 15 78585859 78585859 single base substitution A G intron_variant MELA-AU 15 78585859 78585859 single base substitution A G upstream_gene_variant MELA-AU 15 78586684 78586684 single base substitution G A downstream_gene_variant MELA-AU 15 78586684 78586684 single base substitution G A intron_variant MELA-AU 15 78586684 78586684 single base substitution G A upstream_gene_variant MELA-AU 15 78586691 78586691 single base substitution G A downstream_gene_variant MELA-AU 15 78586691 78586691 single base substitution G A intron_variant MELA-AU 15 78586691 78586691 single base substitution G A upstream_gene_variant MELA-AU 15 78587499 78587499 single base substitution C A exon_variant MELA-AU 15 78587499 78587499 single base substitution C A intron_variant MELA-AU 15 78588928 78588928 single base substitution T C intron_variant MELA-AU 15 78588977 78588977 single base substitution G A intron_variant MELA-AU 15 78589281 78589282 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 15 78590532 78590532 single base substitution C T intron_variant MELA-AU 15 78590617 78590617 single base substitution A T intron_variant MELA-AU 15 78590846 78590846 single base substitution G A intron_variant MELA-AU 15 78591268 78591268 single base substitution G A intron_variant MELA-AU 15 78592813 78592813 single base substitution G A upstream_gene_variant MELA-AU 15 78592884 78592884 single base substitution G A upstream_gene_variant MELA-AU 15 78593368 78593368 single base substitution C T upstream_gene_variant MELA-AU 15 78593594 78593594 single base substitution G A upstream_gene_variant MELA-AU 15 78593745 78593745 single base substitution G A upstream_gene_variant MELA-AU 15 78593883 78593883 single base substitution C T upstream_gene_variant MELA-AU 15 78594025 78594025 single base substitution C A upstream_gene_variant MELA-AU 15 78594900 78594900 single base substitution A T upstream_gene_variant MELA-AU 15 78596430 78596430 single base substitution C T upstream_gene_variant MELA-AU 15 78596783 78596783 single base substitution C G upstream_gene_variant MELA-AU 15 78596853 78596853 single base substitution G A upstream_gene_variant MELA-AU 15 78596989 78596989 single base substitution G A upstream_gene_variant MELA-AU 15 78597125 78597125 single base substitution G A upstream_gene_variant OV-AU 15 78566734 78566736 deletion of <=200bp AGA - downstream_gene_variant OV-AU 15 78570477 78570477 single base substitution G A intron_variant OV-AU 15 78571409 78571409 single base substitution C A downstream_gene_variant OV-AU 15 78571409 78571409 single base substitution C A intron_variant OV-AU 15 78584010 78584010 single base substitution T G downstream_gene_variant OV-AU 15 78584010 78584010 single base substitution T G intron_variant OV-AU 15 78584010 78584010 single base substitution T G upstream_gene_variant OV-AU 15 78584013 78584013 single base substitution G A downstream_gene_variant OV-AU 15 78584013 78584013 single base substitution G A intron_variant OV-AU 15 78584013 78584013 single base substitution G A upstream_gene_variant OV-AU 15 78593873 78593873 single base substitution C T upstream_gene_variant OV-AU 15 78596581 78596581 single base substitution A T upstream_gene_variant OV-US 15 78581979 78581979 single base substitution G A 3_prime_UTR_variant OV-US 15 78581979 78581979 single base substitution G A downstream_gene_variant OV-US 15 78581979 78581979 single base substitution G A exon_variant OV-US 15 78581979 78581979 single base substitution G A missense_variant L182F 544C>T OV-US 15 78581979 78581979 single base substitution G A missense_variant L1F 1C>T OV-US 15 78581979 78581979 single base substitution G A missense_variant L52F 154C>T OV-US 15 78581979 78581979 single base substitution G A missense_variant L89F 265C>T OV-US 15 78581979 78581979 single base substitution G A upstream_gene_variant PACA-AU 15 78585926 78585926 single base substitution C T downstream_gene_variant PACA-AU 15 78585926 78585926 single base substitution C T intron_variant PACA-AU 15 78585926 78585926 single base substitution C T upstream_gene_variant PACA-AU 15 78590854 78590854 single base substitution A G intron_variant PACA-AU 15 78593341 78593341 single base substitution T G upstream_gene_variant PACA-CA 15 78566782 78566782 single base substitution G A downstream_gene_variant PACA-CA 15 78570357 78570357 single base substitution C G 3_prime_UTR_variant PACA-CA 15 78572205 78572205 single base substitution C A downstream_gene_variant PACA-CA 15 78572205 78572205 single base substitution C A intron_variant PACA-CA 15 78572463 78572463 single base substitution A G downstream_gene_variant PACA-CA 15 78572463 78572463 single base substitution A G intron_variant PACA-CA 15 78573077 78573077 single base substitution G A downstream_gene_variant PACA-CA 15 78573077 78573077 single base substitution G A intron_variant PACA-CA 15 78576946 78576946 single base substitution C A downstream_gene_variant PACA-CA 15 78576946 78576946 single base substitution C A exon_variant PACA-CA 15 78576946 78576946 single base substitution C A intron_variant PACA-CA 15 78585780 78585780 single base substitution A G downstream_gene_variant PACA-CA 15 78585780 78585780 single base substitution A G intron_variant PACA-CA 15 78585780 78585780 single base substitution A G upstream_gene_variant PACA-CA 15 78592521 78592521 single base substitution G A upstream_gene_variant PACA-CA 15 78593343 78593343 single base substitution G T upstream_gene_variant PACA-CA 15 78596401 78596401 single base substitution G A upstream_gene_variant PAEN-AU 15 78596590 78596590 single base substitution C A upstream_gene_variant PAEN-IT 15 78585710 78585710 single base substitution A T downstream_gene_variant PAEN-IT 15 78585710 78585710 single base substitution A T intron_variant PAEN-IT 15 78585710 78585710 single base substitution A T upstream_gene_variant PBCA-DE 15 78579023 78579023 single base substitution A C downstream_gene_variant PBCA-DE 15 78579023 78579023 single base substitution A C exon_variant PBCA-DE 15 78579023 78579023 single base substitution A C intron_variant PBCA-DE 15 78579023 78579023 single base substitution A C upstream_gene_variant PBCA-DE 15 78585630 78585630 single base substitution C A downstream_gene_variant PBCA-DE 15 78585630 78585630 single base substitution C A intron_variant PBCA-DE 15 78585630 78585630 single base substitution C A upstream_gene_variant PBCA-DE 15 78592421 78592421 single base substitution G C upstream_gene_variant PBCA-DE 15 78592702 78592702 single base substitution G A upstream_gene_variant PBCA-DE 15 78593656 78593656 single base substitution C T upstream_gene_variant PRAD-CA 15 78569339 78569339 single base substitution T C downstream_gene_variant PRAD-CA 15 78569460 78569460 single base substitution G A downstream_gene_variant PRAD-UK 15 78566698 78566698 single base substitution G C downstream_gene_variant PRAD-UK 15 78579373 78579375 deletion of <=200bp AAT - downstream_gene_variant PRAD-UK 15 78579373 78579375 deletion of <=200bp AAT - intron_variant PRAD-UK 15 78579373 78579375 deletion of <=200bp AAT - upstream_gene_variant PRAD-UK 15 78581382 78581382 single base substitution C T downstream_gene_variant PRAD-UK 15 78581382 78581382 single base substitution C T intron_variant PRAD-UK 15 78581382 78581382 single base substitution C T upstream_gene_variant PRAD-UK 15 78585152 78585152 single base substitution T G 3_prime_UTR_variant PRAD-UK 15 78585152 78585152 single base substitution T G downstream_gene_variant PRAD-UK 15 78585152 78585152 single base substitution T G exon_variant PRAD-UK 15 78585152 78585152 single base substitution T G intron_variant PRAD-UK 15 78585152 78585152 single base substitution T G upstream_gene_variant PRAD-UK 15 78585494 78585494 single base substitution G C downstream_gene_variant PRAD-UK 15 78585494 78585494 single base substitution G C intron_variant PRAD-UK 15 78585494 78585494 single base substitution G C upstream_gene_variant PRAD-UK 15 78590269 78590269 single base substitution T C intron_variant RECA-EU 15 78567077 78567077 single base substitution C T downstream_gene_variant RECA-EU 15 78575527 78575527 single base substitution C T downstream_gene_variant RECA-EU 15 78575527 78575527 single base substitution C T intron_variant RECA-EU 15 78585164 78585164 single base substitution C T 3_prime_UTR_variant RECA-EU 15 78585164 78585164 single base substitution C T downstream_gene_variant RECA-EU 15 78585164 78585164 single base substitution C T exon_variant RECA-EU 15 78585164 78585164 single base substitution C T intron_variant RECA-EU 15 78585164 78585164 single base substitution C T upstream_gene_variant RECA-EU 15 78592513 78592513 single base substitution T C upstream_gene_variant SKCA-BR 15 78570384 78570384 single base substitution T C 3_prime_UTR_variant SKCA-BR 15 78576072 78576073 deletion of <=200bp CA - downstream_gene_variant SKCA-BR 15 78576072 78576073 deletion of <=200bp CA - exon_variant SKCA-BR 15 78576072 78576073 deletion of <=200bp CA - intron_variant SKCA-BR 15 78576295 78576295 insertion of <=200bp - GC downstream_gene_variant SKCA-BR 15 78576295 78576295 insertion of <=200bp - GC exon_variant SKCA-BR 15 78576295 78576295 insertion of <=200bp - GC intron_variant SKCA-BR 15 78577897 78577897 single base substitution C T downstream_gene_variant SKCA-BR 15 78577897 78577897 single base substitution C T exon_variant SKCA-BR 15 78577897 78577897 single base substitution C T intron_variant SKCA-BR 15 78578071 78578071 single base substitution A T downstream_gene_variant SKCA-BR 15 78578071 78578071 single base substitution A T exon_variant SKCA-BR 15 78578071 78578071 single base substitution A T intron_variant SKCA-BR 15 78578071 78578071 single base substitution A T splice_region_variant SKCA-BR 15 78578185 78578185 single base substitution G A downstream_gene_variant SKCA-BR 15 78578185 78578185 single base substitution G A exon_variant SKCA-BR 15 78578185 78578185 single base substitution G A intron_variant SKCA-BR 15 78578483 78578483 single base substitution G T downstream_gene_variant SKCA-BR 15 78578483 78578483 single base substitution G T exon_variant SKCA-BR 15 78578483 78578483 single base substitution G T intron_variant SKCA-BR 15 78578483 78578483 single base substitution G T splice_region_variant SKCA-BR 15 78578483 78578483 single base substitution G T upstream_gene_variant SKCA-BR 15 78582994 78582994 single base substitution G A downstream_gene_variant SKCA-BR 15 78582994 78582994 single base substitution G A intron_variant SKCA-BR 15 78582994 78582994 single base substitution G A upstream_gene_variant SKCA-BR 15 78583158 78583158 insertion of <=200bp - CTT downstream_gene_variant SKCA-BR 15 78583158 78583158 insertion of <=200bp - CTT intron_variant SKCA-BR 15 78583158 78583158 insertion of <=200bp - CTT upstream_gene_variant SKCA-BR 15 78585012 78585012 single base substitution G A 3_prime_UTR_variant SKCA-BR 15 78585012 78585012 single base substitution G A downstream_gene_variant SKCA-BR 15 78585012 78585012 single base substitution G A exon_variant SKCA-BR 15 78585012 78585012 single base substitution G A intron_variant SKCA-BR 15 78585012 78585012 single base substitution G A missense_variant R89C 265C>T SKCA-BR 15 78585012 78585012 single base substitution G A upstream_gene_variant SKCA-BR 15 78586794 78586794 single base substitution T C downstream_gene_variant SKCA-BR 15 78586794 78586794 single base substitution T C intron_variant SKCA-BR 15 78586794 78586794 single base substitution T C upstream_gene_variant SKCA-BR 15 78589017 78589017 single base substitution T A intron_variant SKCA-BR 15 78590997 78590997 single base substitution T C intron_variant SKCA-BR 15 78592415 78592415 single base substitution T G upstream_gene_variant SKCA-BR 15 78595767 78595768 deletion of <=200bp CT - upstream_gene_variant SKCA-BR 15 78595930 78595930 single base substitution G A upstream_gene_variant SKCA-BR 15 78596441 78596441 single base substitution G A upstream_gene_variant SKCA-BR 15 78596442 78596442 single base substitution G A upstream_gene_variant SKCM-US 15 78567844 78567844 single base substitution G A downstream_gene_variant SKCM-US 15 78567973 78567973 single base substitution C T downstream_gene_variant SKCM-US 15 78580681 78580681 single base substitution G A 3_prime_UTR_variant SKCM-US 15 78580681 78580681 single base substitution G A downstream_gene_variant SKCM-US 15 78580681 78580681 single base substitution G A synonymous_variant S109S 327C>T SKCM-US 15 78580681 78580681 single base substitution G A synonymous_variant S202S 606C>T SKCM-US 15 78580681 78580681 single base substitution G A synonymous_variant S21S 63C>T SKCM-US 15 78580681 78580681 single base substitution G A synonymous_variant S72S 216C>T SKCM-US 15 78580681 78580681 single base substitution G A upstream_gene_variant STAD-US 15 78566640 78566640 single base substitution A G downstream_gene_variant STAD-US 15 78566648 78566648 single base substitution C T downstream_gene_variant STAD-US 15 78568044 78568044 single base substitution G A downstream_gene_variant STAD-US 15 78582013 78582013 single base substitution T C 3_prime_UTR_variant STAD-US 15 78582013 78582013 single base substitution T C downstream_gene_variant STAD-US 15 78582013 78582013 single base substitution T C exon_variant STAD-US 15 78582013 78582013 single base substitution T C synonymous_variant G170G 510A>G STAD-US 15 78582013 78582013 single base substitution T C synonymous_variant G40G 120A>G STAD-US 15 78582013 78582013 single base substitution T C synonymous_variant G77G 231A>G STAD-US 15 78582013 78582013 single base substitution T C upstream_gene_variant STAD-US 15 78582045 78582045 single base substitution C A 3_prime_UTR_variant STAD-US 15 78582045 78582045 single base substitution C A downstream_gene_variant STAD-US 15 78582045 78582045 single base substitution C A exon_variant STAD-US 15 78582045 78582045 single base substitution C A missense_variant G160W 478G>T STAD-US 15 78582045 78582045 single base substitution C A missense_variant G30W 88G>T STAD-US 15 78582045 78582045 single base substitution C A missense_variant G67W 199G>T STAD-US 15 78582045 78582045 single base substitution C A upstream_gene_variant THCA-SA 15 78573745 78573745 single base substitution G C downstream_gene_variant THCA-SA 15 78573745 78573745 single base substitution G C intron_variant THCA-SA 15 78585106 78585106 single base substitution C T 3_prime_UTR_variant THCA-SA 15 78585106 78585106 single base substitution C T downstream_gene_variant THCA-SA 15 78585106 78585106 single base substitution C T exon_variant THCA-SA 15 78585106 78585106 single base substitution C T intron_variant THCA-SA 15 78585106 78585106 single base substitution C T synonymous_variant Q57Q 171G>A THCA-SA 15 78585106 78585106 single base substitution C T upstream_gene_variant UCEC-US 15 78565441 78565441 single base substitution G A downstream_gene_variant UCEC-US 15 78566680 78566680 single base substitution G A downstream_gene_variant UCEC-US 15 78566744 78566744 single base substitution T C downstream_gene_variant UCEC-US 15 78568044 78568044 single base substitution G A downstream_gene_variant UCEC-US 15 78568052 78568052 single base substitution G A downstream_gene_variant UCEC-US 15 78572425 78572425 single base substitution G A downstream_gene_variant UCEC-US 15 78572425 78572425 single base substitution G A intron_variant UCEC-US 15 78577679 78577679 single base substitution G A downstream_gene_variant UCEC-US 15 78577679 78577679 single base substitution G A exon_variant UCEC-US 15 78577679 78577679 single base substitution G A intron_variant UCEC-US 15 78577679 78577679 single base substitution G A missense_variant S121L 362C>T UCEC-US 15 78577679 78577679 single base substitution G A missense_variant S158L 473C>T UCEC-US 15 78577679 78577679 single base substitution G A missense_variant S251L 752C>T UCEC-US 15 78578400 78578400 single base substitution G A downstream_gene_variant UCEC-US 15 78578400 78578400 single base substitution G A exon_variant UCEC-US 15 78578400 78578400 single base substitution G A intron_variant UCEC-US 15 78578400 78578400 single base substitution G A synonymous_variant D114D 342C>T UCEC-US 15 78578400 78578400 single base substitution G A synonymous_variant D151D 453C>T UCEC-US 15 78578400 78578400 single base substitution G A synonymous_variant D244D 732C>T UCEC-US 15 78578400 78578400 single base substitution G A upstream_gene_variant UCEC-US 15 78578445 78578445 single base substitution G A downstream_gene_variant UCEC-US 15 78578445 78578445 single base substitution G A exon_variant UCEC-US 15 78578445 78578445 single base substitution G A intron_variant UCEC-US 15 78578445 78578445 single base substitution G A synonymous_variant S136S 408C>T UCEC-US 15 78578445 78578445 single base substitution G A synonymous_variant S229S 687C>T UCEC-US 15 78578445 78578445 single base substitution G A synonymous_variant S99S 297C>T UCEC-US 15 78578445 78578445 single base substitution G A upstream_gene_variant UCEC-US 15 78580723 78580723 single base substitution G A downstream_gene_variant UCEC-US 15 78580723 78580723 single base substitution G A splice_region_variant UCEC-US 15 78580723 78580723 single base substitution G A upstream_gene_variant UCEC-US 15 78582307 78582307 single base substitution G T 3_prime_UTR_variant UCEC-US 15 78582307 78582307 single base substitution G T downstream_gene_variant UCEC-US 15 78582307 78582307 single base substitution G T exon_variant UCEC-US 15 78582307 78582307 single base substitution G T missense_variant L152I 454C>A UCEC-US 15 78582307 78582307 single base substitution G T missense_variant L22I 64C>A UCEC-US 15 78582307 78582307 single base substitution G T missense_variant L59I 175C>A UCEC-US 15 78582307 78582307 single base substitution G T upstream_gene_variant

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand I2L-P24Ta-Tumor-Biopsy COSM5363008 c.257C>T p.A86V Substitution - Missense 15:78292678-78292678 - ESCC_BICR_008T COSM5428827 c.505G>A p.D169N Substitution - Missense 15:78289676-78289676 - I2L-P24Tb-Tumor-Biopsy COSM5363008 c.257C>T p.A86V Substitution - Missense 15:78292678-78292678 - TCGA-B5-A0JY-01 COSM965350 c.454C>A p.L152I Substitution - Missense 15:78289965-78289965 - YUKAT COSM5383876 c.816T>A p.D272E Substitution - Missense 15:78285273-78285273 - TCGA-AA-3697-01 COSM1374775 c.211G>T p.D71Y Substitution - Missense 15:78292724-78292724 - LIM1899 COSM4640025 c.595T>C p.S199P Substitution - Missense 15:78288350-78288350 - TCGA-BR-6452-01 COSM4057131 c.510A>G p.G170G Substitution - coding silent 15:78289671-78289671 - TCGA-BR-6452-01 COSM4057132 c.478G>T p.G160W Substitution - Missense 15:78289703-78289703 - RK052_C01 COSM1629696 c.430T>C p.L144L Substitution - coding silent 15:78289989-78289989 - HDC87 COSM4636936 c.480G>T p.G160G Substitution - coding silent 15:78289701-78289701 - PD13755a COSM5777087 c.513C>A p.I171I Substitution - coding silent 15:78289668-78289668 - S00827 COSM316544 c.822_823GG>AT p.Q274>? Complex 15:78285266-78285267 - KM12 COSM2011048 c.554C>G p.T185S Substitution - Missense 15:78289627-78289627 - S00827 COSM316544 c.822_823GG>AT p.Q274>? Complex 15:78285266-78285267 - QGP1 COSM2011051 c.293A>G p.Q98R Substitution - Missense 15:78292642-78292642 - 24T COSM109469 c.243C>T p.S81S Substitution - coding silent 15:78292692-78292692 - TCGA-B5-A11E-01 COSM965347 c.732C>T p.D244D Substitution - coding silent 15:78286058-78286058 - sysucc-1171T COSM4254353 c.657-10C>T p.? Unknown 15:78286143-78286143 - TCGA-AA-A00N-01 COSM278127 c.752C>T p.S251L Substitution - Missense 15:78285337-78285337 - TCGA-D8-A27G-01 COSM3816824 c.156G>C p.E52D Substitution - Missense 15:78292779-78292779 - TCGA-06-5858-01 COSM3401943 c.712G>A p.V238I Substitution - Missense 15:78286078-78286078 - ESCC_76 COSM5635101 c.132G>A p.V44V Substitution - coding silent 15:78293181-78293181 - 2_PRE-TREATMENT COSM1722947 c.147-10C>T p.? Unknown 15:78292798-78292798 - TCGA-AP-A059-01 COSM965349 c.564C>T p.G188G Substitution - coding silent 15:78288381-78288381 - BZ20 COSM5758541 c.695C>T p.A232V Substitution - Missense 15:78286095-78286095 - Pat_59_A COSM5849854 c.469-1G>A p.? Unknown 15:78289713-78289713 - ESCC_109 COSM5638893 c.789G>A p.T263T Substitution - coding silent 15:78285300-78285300 - 046T COSM1729738 c.51T>A p.D17E Substitution - Missense 15:78293262-78293262 - CSCC-49-T COSM4449756 c.319+1G>A p.? Unknown 15:78292615-78292615 - CSCC-35-T COSM4495300 c.450C>T p.F150F Substitution - coding silent 15:78289969-78289969 - T2940 COSM4741018 c.476A>G p.D159G Substitution - Missense 15:78289705-78289705 - TCGA-AM-5820-01 COSM3690556 c.364G>A p.A122T Substitution - Missense 15:78290055-78290055 - I2L-P24Tb-Tumor-Organoid COSM5363008 c.257C>T p.A86V Substitution - Missense 15:78292678-78292678 - TCGA-D1-A17Q-01 COSM278127 c.752C>T p.S251L Substitution - Missense 15:78285337-78285337 - TC71 COSM4578529 c.580C>T p.R194C Substitution - Missense 15:78288365-78288365 - SE3 COSM1165813 c.797G>C p.C266S Substitution - Missense 15:78285292-78285292 - TCGA-CM-6162-01 COSM1374772 c.599C>T p.P200L Substitution - Missense 15:78288346-78288346 - TCGA-13-0755-01 COSM77012 c.544C>T p.L182F Substitution - Missense 15:78289637-78289637 - TCGA-EE-A2MH-06 COSM3504294 c.606C>T p.S202S Substitution - coding silent 15:78288339-78288339 - I2L-P24Ta-Tumor-Organoid COSM5363008 c.257C>T p.A86V Substitution - Missense 15:78292678-78292678 - TCGA-CM-4746-01 COSM1374773 c.569C>T p.A190V Substitution - Missense 15:78288376-78288376 - TCGA-IR-A3LK-01 COSM4816536 c.820C>T p.Q274* Substitution - Nonsense 15:78285269-78285269 - PT08_2 COSM5893857 c.698C>T p.S233F Substitution - Missense 15:78286092-78286092 - CLL125 COSM1290435 c.511A>G p.I171V Substitution - Missense 15:78289670-78289670 - PD13755a COSM5794729 c.512T>A p.I171N Substitution - Missense 15:78289669-78289669 - TCGA-BS-A0U8-01 COSM965348 c.687C>T p.S229S Substitution - coding silent 15:78286103-78286103 - PT08_1 COSM5893857 c.698C>T p.S233F Substitution - Missense 15:78286092-78286092 - 2_RESISTANT COSM1722947 c.147-10C>T p.? Unknown 15:78292798-78292798 - OLID13 COSM132786 c.568G>A p.A190T Substitution - Missense 15:78288377-78288377 - T44 COSM5342634 c.776G>A p.W259* Substitution - Nonsense 15:78285313-78285313 - TCGA-61-1895-01 COSM1323819 c.829-1G>A p.? Unknown 15:78283522-78283522 - PT21_2 COSM5901928 c.370G>A p.G124R Substitution - Missense 15:78290049-78290049 - TCGA-GM-A2DD-01 COSM5232540 c.576delC p.I193fs*4 Deletion - Frameshift 15:78288369-78288369 - BD117T COSM5507426 c.398T>C p.F133S Substitution - Missense 15:78290021-78290021 - sysucc-923T COSM4254353 c.657-10C>T p.? Unknown 15:78286143-78286143 - YUOTHO COSM5383877 c.344C>T p.S115F Substitution - Missense 15:78290075-78290075 - TCGA-AA-3697-01 COSM1374776 c.210G>T p.V70V Substitution - coding silent 15:78292725-78292725 - RK217_C01 COSM3741685 c.367A>G p.T123A Substitution - Missense 15:78290052-78290052 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.513055 15q25.1 609540

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A G IntronicSNV . c.1-50T>C 15 78588078 RCCC A T IntronicSNV . c.320-567T>A 15 78583008 HC C A IntronicSNV . c.41-16G>T 15 78585630 MB C A SpliceDonorSNV . c.319+1G>T 15 78584957 LUAD CC AT Missense p.D275Y c.822_823delinsAT 15 78577608 SCLC C G IntronicSNV . c.12+63G>C 15 78587954 HC G A IntronicSNV . c.1-99C>T 15 78588127 CM G A IntronicSNV . c.40+53C>T 15 78587235 CM G A Missense p.L182F c.544C>T 15 78581979 OV G A Synonymous p.S202S c.606C>T 15 78580681 CM G A Synonymous p.S229S c.687C>T 15 78578445 UCEC T C Missense p.I171V c.511A>G 15 78582012 CLL