Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 15 84205679 rs17841192 C T rs17841192 4.22E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_drug 15 84235930 rs2562769 G T rs2562769 2.95E-04 ATORVASTATIN SERINE ENDOPEPTIDASES|PYRROLES|PCSK9 PROTEIN, HUMAN|HEPTANOIC ACIDS|APOLIPOPROTEINS E|PROPROTEIN CONVERTASES Response to statin treatment (atorvastatin), change in cholesterol levels HPOID:0001626 DOID:1287 A intron GWASdb_drug 15 84257351 rs7182482 G A rs7182482 3.06E-04 ATORVASTATIN SERINE ENDOPEPTIDASES|PYRROLES|PCSK9 PROTEIN, HUMAN|HEPTANOIC ACIDS|APOLIPOPROTEINS E|PROPROTEIN CONVERTASES Response to statin treatment (atorvastatin), change in cholesterol levels HPOID:0001626 DOID:1287 G intron GWASdb_drug 15 84129515 rs6602977 A G rs6602977 9.47E-05 Orofacial clefts HPOID:0000202 DOID:0050567 G intron GWASdb_trait 15 84135138 rs9920377 G A rs9920377 6.37E-04 Response to taxane treatment (placlitaxel) HPOID:0100526 DOID:1324 A intron GWASdb_trait 15 84173859 rs10906975 A G rs10906975 3.59E-04 Body mass index HPOID:0001507 DOID:9970 G intron GWASdb_trait 15 84173859 rs10906975 A G rs10906975 4.96E-04 Body mass index HPOID:0001507 DOID:9970 G intron GWASdb_trait 15 84178679 rs1491579 T C rs1491579 1.47E-05 Alcohol consumption HPOID:0000707 DOID:1574|DOID:0050741 T intron GWASdb_trait 15 84179115 rs12905964 C T rs12905964 8.63E-05 Alcohol consumption HPOID:0000707 DOID:1574|DOID:0050741 C intron GWASdb_trait 15 84201446 rs2732150 T C rs2732150 4.86E-04 Coronary Artery Disease HPOID:0001677 DOID:3393 T intron GWASdb_trait 15 84203402 rs2642820 A G rs2642820 6.10E-06 Urinary metabolites HPOID:0000079 DOID:557 A intron GWASdb_trait 15 84205565 rs2201101 G T rs2201101 8.73E-05 Blood Pressure HPOID:0011025 DOID:10763 T intron GWASdb_trait 15 84205679 rs17841192 C T rs17841192 4.22E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 C intron GWASdb_trait 15 84235930 rs2562769 G T rs2562769 2.95E-04 Response to statin treatment (atorvastatin), change in cholesterol levels HPOID:0001626 DOID:1287 A intron GWASdb_trait 15 84235930 rs2562769 G T rs2562769 1.10E-05 Urinary metabolites HPOID:0000079 DOID:557 A intron GWASdb_trait 15 84242585 rs12900490 T C rs12900490 2.90E-05 Urinary metabolites HPOID:0000079 DOID:557 T intron GWASdb_trait 15 84257351 rs7182482 G A rs7182482 3.06E-04 Response to statin treatment (atorvastatin), change in cholesterol levels HPOID:0001626 DOID:1287 G intron GWASdb_trait 15 84263750 rs2562764 C T rs2562764 4.57E-04 Multiple complex diseases HPOID:0000118 NA A intron GWASdb_trait 15 84273405 rs17158772 A G rs17158772 4.40E-07 Urinary metabolites HPOID:0000079 DOID:557 A intron GWASdb_trait 15 84274980 rs1896796 A G rs1896796 0.000171 Schizophrenia HPOID:0100753 DOID:5419 T intron GWASdb_trait 15 84286492 rs2562784 A G rs2562784 6.00E-08 Height HPOID:0000002 NA T intron GWASdb_trait

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000140600.16 SH3GL3 603362