PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus OGT TOM1L1 22863883 biogrid exp GP GP P P G G GP GP GP GP GP G GP P GP GP G P GP GP GP GP GP G TOM1L1 SP100 22863883 biogrid exp GP GP P P G GP GP GP GP GP GP G GP P GP P G P GP GP GP P GP P G TOM1L1 COPS7A 16169070 hprd,biogrid,i2d,mint,intact exp GP GP P G GP GP GP G GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 TSG101 15611048 hprd,biogrid,mint,intact exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 VAV2 18654987 biogrid,intact exp GP GP P P G G GP GP GP GP G G GP P GP GP G P GP GP GP P GP GP G ZPR1 TOM1L1 22863883 biogrid exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 NIF3L1 22863883 biogrid exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 VCP 21900206 biogrid,mint,intact exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 ALAD 22863883 biogrid exp G GP P P G G GP GP GP G G G G P G GP G P GP GP G GP GP TOM1L1 HNRNPH2 16169070 i2d exp P P P P P P P P P P P P P P P P P P P P P TOM1L1 UBXN4 16169070 hprd,biogrid,i2d,mint,intact exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 MAP4K4 20936779 i2d exp G G P G GP G GP GP GP G G GP P G G G G G GP GP GP G TOM1L1 EEA1 19798056 mint,intact exp GP GP P P G G GP GP G GP G G GP P GP GP G P GP GP GP GP GP G TOM1L1 ARPC4 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G TOM1L1 UBC 15047686 biogrid exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 MAP3K3 21900206 biogrid,mint,intact exp G G P P G GP G GP G GP GP G GP P G G G P G G GP P GP G G TOM1L1 OPCML 16169070 i2d exp G G TOM1L1 AMFR 21900206 biogrid,mint,intact exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 CRTAP 22863883 biogrid exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 BAG1 22863883 biogrid exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G ARPC5 TOM1L1 22863883 biogrid exp G GP P P G GP GP GP GP GP G G GP P GP GP G P GP GP GP P GP GP G TOM1L1 NOMO1 16169070 hprd,biogrid,i2d,mint,intact exp P P P P P P P P P P P P P P P P TOM1L1 STAT5B 22863883 biogrid exp GP GP P P G GP GP GP GP GP GP G GP P G G G P GP GP GP P GP GP G TOM1L1 METTL1 22863883 biogrid exp GP GP P P G G GP GP GP GP GP G GP P GP GP G P GP G GP P GP GP G TOM1L1 PPME1 22863883 biogrid exp GP GP P P G G GP GP G GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 LEPRE1 22863883 biogrid exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 HSPBP1 22863883 biogrid exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 AARS 22863883 biogrid exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 SURF2 22863883 biogrid exp P P P P P P P P P P G P P P P P P P P GP TOM1L1 ACTR2 22863883 biogrid exp GP GP P P G G GP GP GP GP GP G GP P G GP G P GP GP GP P GP GP G TOM1L1 TUBA1B 21900206 biogrid,mint,intact exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G ARPC2 TOM1L1 22863883 biogrid exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 GLUD2 16169070 hprd,biogrid,mint,intact exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 GSN 16169070 hprd,biogrid,i2d,mint,intact exp GP GP P P G G GP GP G GP GP G G P GP GP G P G GP G P GP G G TOM1L1 PKN1 22939629 biogrid exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 PWP2 16169070 hprd,biogrid,i2d,mint,intact exp GP G P G G GP GP G G G G GP P G GP P GP P GP GP G G PHYH TOM1L1 16169070 hprd,biogrid,i2d,mint,intact exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 OSGEP 22863883 biogrid exp GP GP P G GP GP GP G GP G G GP P GP GP G GP GP GP GP GP G ARPC1B TOM1L1 22863883 biogrid exp G G P P G G GP GP G GP GP G G P G G G P G G G P GP GP G TOM1L1 RAB18 16169070 hprd,i2d,mint,intact exp GP GP P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 CWF19L1 16169070 hprd,biogrid,i2d,mint,intact exp GP P P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 CCDC47 16169070 hprd,biogrid,i2d,mint,intact exp GP GP P P G GP GP GP GP GP GP G GP P G GP G P GP GP GP P GP GP G TOM1L1 FAM208A 16169070 hprd,i2d,mint,intact exp G G P P G G GP GP GP GP GP G GP P G GP G P GP GP GP P GP GP G TOM1L1 DPP9 22863883 biogrid exp GP GP P P G GP GP GP G GP G G GP P GP GP G P GP GP GP P GP GP G TOM1L1 HNRNPH1 16169070 hprd,mint,intact exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 RPRD1B 22863883 biogrid exp G G G G G G G G G G G G G G G G G G G G TOM1L1 TP53RK 22863883 biogrid exp GP GP P P G GP GP P GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 PELP1 16169070 hprd,biogrid,i2d,mint,intact exp GP GP P P G GP GP GP GP GP GP G GP P GP P G P GP GP GP P GP GP G TOM1L1 GLUD1 16169070 i2d exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 PDPN 16169070 hprd,biogrid,i2d,mint,intact exp G P G G P GP G P GP G G G G G TOM1L1 CELF1 16169070 hprd,biogrid,i2d,mint,intact exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G NDC80 TOM1L1 16169070 hprd,biogrid,i2d,mint,intact exp G G TOM1L1 CLTC 16412388,19798056,17785434 biogrid,mint,intact exp, ortho GP GP P P G GP GP GP GP GP GP G GP P G GP G P GP GP GP P GP GP G TOM1L1 GRB2 12345679,11711534,19798056, 25402006, 21836163 hprd,biogrid,mint,intact exp, ortho, pred GP GP P P G G GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 FYN 11711534,20182632, 25402006, 21836163 hprd,biogrid exp, ortho, pred G GP P P G G GP GP GP G GP G G P G G G G G G P G G G TOM1L1 SRC 17785434, 21836163 biogrid exp, pred GP GP P GP G GP G G G G GP P G G G GP GP GP P GP GP G TOM1L1 PIK3R1 11711534, 21836163 hprd exp, pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 TOLLIP 21903422,21988832,20936779,16412388,15047686, 25402006, 21836163 innatedb,hprd,biogrid,i2d,intact exp, pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP GP GP G HGS TOM1L1 15611048, 23023127 hprd,biogrid,mint,intact exp, pred GP GP P P G GP GP GP G GP G G GP P GP GP G P GP GP GP GP GP G TOM1L1 EGFR 19798056,12577067, 25402006 biogrid,i2d,mint,intact exp, pred GP GP P G G GP GP GP G G G GP P G G G P GP G GP GP GP G TOM1 TOM1L1 19798056, 25402006, 23023127 mint,intact exp, pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 YWHAE ortho GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 CD2AP 25402006 pred GP GP P P G G GP GP GP GP GP G GP P G GP G P GP GP GP P GP GP TOM1L1 GGA1 23023127 pred GP GP P P G GP GP GP G GP GP G GP P GP GP G P GP GP GP P GP GP G SYNJ1 TOM1L1 25402006 pred GP P P P G G GP GP G GP GP G GP P GP P G P GP G GP P GP GP TOM1L1 LIN7B 23023127 pred G G P G G GP G GP G G GP P GP G G G GP GP GP G TOM1L1 STAM 25402006, 23023127 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP GP GP G TOM1L1 IGF2R 16082366 pred GP GP P G GP GP GP GP GP GP G GP P G GP G P GP GP GP P GP GP G TOM1L1 RCAN1 25402006 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 DNM3 25402006 pred G G G G G G G G G G G G G G G TOM1L1 IL1R1 25402006 pred GP GP P P G G GP GP GP GP GP G GP P G GP G P GP GP GP P GP GP G TOM1L1 STAM2 25402006, 23023127 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 ITSN2 16082366 pred G G P G G GP GP GP G G G GP P G GP G P GP G GP GP GP G TOM1L1 EPS15 25402006 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 REPS2 16082366 pred G G P P G GP GP GP GP GP GP P GP GP G P GP G GP P GP P TLR2 TOM1L1 25402006 pred G G G G G G G G G G G G G G G TOM1L1 DRD3 25402006 pred TOM1L1 DAZAP2 25402006 pred G G G G G G G G G G G G G G G G G G G G TOM1L1 ERBB2 25402006 pred GP G G G GP GP G G G G GP G G G P GP G GP G G G TOM1L1 RHOG 25402006 pred GP GP P P G G G GP G GP GP G G P G G G G G G P G G G TOM1L1 AP2S1 25402006 pred G G G G G G G G G G G G G G G G G G G G SPRY2 TOM1L1 25402006 pred GP GP P P G GP GP GP GP GP GP G GP P G GP G P GP GP GP GP GP G TOM1L1 IL1RAP 25402006 pred GP P P P P P G GP P G P P G G P P GP P G TOM1L1 ACTG2 25402006 pred G G G G GP GP GP GP GP G GP G GP G G G GP GP GP G TOM1L1 AP2B1 25402006 pred G GP P P G G GP GP G GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 HCN2 25402006 pred G G SYNJ2 TOM1L1 25402006 pred GP GP P P G GP GP GP GP P GP G GP P GP GP G P GP GP GP P GP P G TOM1L1 RPL31 25402006 pred G G G G G G G G G G G G G G G G G G G G INPPL1 TOM1L1 25402006 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 STX1A 23023127 pred G G P G G P G G G GP P GP G G G GP GP G G TOM1L1 CLINT1 23023127 pred GP GP P P G GP GP GP GP GP GP G GP P G GP G P GP GP GP P GP GP G TOM1L1 ANXA2 25402006 pred GP G P P G G GP GP GP GP GP G G P GP GP G P GP G G P GP GP G TOM1L1 SORL1 16082366 pred GP GP P P G GP GP GP GP GP G G GP P GP GP G P GP GP GP P GP GP G TOM1L1 DOCK1 25402006 pred GP G P P G GP GP GP GP GP G G GP P GP GP G P GP GP GP P GP GP G TOM1L1 COG2 16082366 pred G G G G G G G G G G G G G G G G G G G G TOM1L1 IRAK1 25402006 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 HSPA5 25402006 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 USP8 25402006 pred G GP P P G G GP GP G GP G G GP P G GP G P GP G GP GP GP G TOM1L1 GGA3 23023127 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P G GP GP P GP GP G TOM1L1 ERBB3 25402006 pred GP GP P P G GP GP GP GP GP GP G GP P P GP G P GP GP GP P GP GP G TOM1L1 GGA2 23023127 pred GP GP P G G GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 VAV3 25402006 pred GP GP P P G GP GP GP GP GP GP G GP P G GP G P GP GP GP P GP GP G TOM1L1 DAB2 25402006 pred G GP G G G GP G GP G G G G G G P G G G G G G TOM1L1 VAV1 25402006 pred GP GP P P G P P P GP GP GP G GP P G GP G P G GP P P GP GP G TOM1L1 LYST 16082366 pred G G G G G G G G G G G G G G G G G G G G TOM1L1 RPS25 25402006 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 NCKIPSD 25402006 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP G GP P GP GP G SPRY1 TOM1L1 25402006 pred GP GP P P G GP GP GP GP GP GP G GP P G GP G P GP GP GP P GP GP G TOM1L1 MAP4K3 25402006 pred G G P P G G GP GP G GP GP G GP P G GP G P G G GP GP GP G TOM1L1 M6PR 16082366 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G WDR1 TOM1L1 25402006 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 CBL 25402006 pred G GP P P G G GP GP G GP GP G G P GP G G G G G P G GP G TOM1L1 SYP 25402006 pred GP P G P P G P P GP G G P P TOM1L1 KRT18 25402006 pred GP GP G GP GP GP GP G G GP G GP G P GP GP GP GP G G TOM1L1 ITSN1 16082366 pred G GP P G GP GP GP GP GP GP G GP P G G G P G GP GP GP GP G TOM1L1 SYNRG 16082366 pred G G G G G G G G G G G G G G G G G G G G TOM1L1 KRT8 25402006 pred GP G G G GP GP GP GP G G GP GP GP G P GP GP GP GP G G TOM1L1 DARS 25402006 pred GP GP P P G G GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 KRT7 25402006 pred GP GP P GP G GP P GP GP G P STX16 TOM1L1 16082366 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G TOM1L1 NEK3 25402006 pred GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP GP GP G TOM1L1 LAT2 25402006 pred G G P G G G GP GP G G GP G G G G P G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P49448 O75674 two hybrid 16169070 direct interaction X 2 Q96A33 O75674 two hybrid 16169070 direct interaction X 2 O75674 O14964 two hybrid 15611048 direct interaction X 2 O75674 O14964 two hybrid 15611048 direct interaction X 2 O75674 P00533 affinity chromatography technology 19798056 physical association X 2 O75674 P00533 affinity chromatography technology 19798056 physical association X 2 O75674 A4D275 biochemical 22863883 colocalization X 2 O75674 O15511 biochemical 22863883 colocalization X 2 O75674 P61160-2 biochemical 22863883 colocalization X 2 O75674 Q9NZL4-2 biochemical 22863883 colocalization X 2 O75674 Q32P28-2 biochemical 22863883 colocalization X 2 O75674 biochemical 22863883 colocalization X 2 O75674 Q9Y570 biochemical 22863883 colocalization X 2 O75674 biochemical 22863883 colocalization X 2 O75674 Q15269 two hybrid 16169070 direct interaction X 2 O75674 Q86YL7-6 two hybrid 16169070 direct interaction X 2 O75674 Q92575 two hybrid 16169070 direct interaction X 2 O75674 two hybrid 16169070 direct interaction X 2 O75674 Q8IZL8 two hybrid 16169070 direct interaction X 2 O75674 Q9UBW8 two hybrid 16169070 direct interaction X 2 O75674 P62993-2 pull down 11711534 direct interaction X 2 O75674 P52735 two hybrid 18654987 direct interaction X 2 O75674 P52735 affinity chromatography technology 18654987 physical association X 2 Q9NQG5 O75674 biochemical 22863883 colocalization X 2 Q9UKV5 O75674 two hybrid 21900206 direct interaction X 2 P0CG48 O75674 affinity chromatography technology 22053931 physical association X 2 P0CG48 O75674 pull down 15047686 direct interaction X 2 P0CG48 O75674 affinity chromatography technology 21139048 physical association X 2 P0CG48 O75674 affinity chromatography technology 21890473 physical association X 2 P0CG48 O75674 affinity chromatography technology 21906983 physical association X 2 P55072 O75674 two hybrid 21900206 direct interaction X 2 Q15155 O75674 two hybrid 16169070 direct interaction X 2 P12931 O75674 affinity chromatography technology 17785434 physical association X 2 P12931 O75674 affinity chromatography technology 17785434 physical association X 2 P68363 O75674 two hybrid 21900206 direct interaction X 2 O75674 Q99816 two hybrid 15611048 direct interaction X 2 O75674 Q99816 two hybrid 15611048 direct interaction X 2 O75674 Q00610 affinity chromatography technology 16412388 physical association X 2 O75674 P06241-3 affinity chromatography technology 20182632 physical association X 2 O75674 P06241-3 affinity chromatography technology 20182632 physical association X 2 O75674 Q00610 pull down 19798056 direct interaction X 2 O75674 Q00610 pull down 17785434 direct interaction X 2 O75674 Q00610 affinity chromatography technology 17785434 physical association X 2 O75674 Q00610 imaging technique 17785434 colocalization X 2 O75674 Q00610 pull down 17785434 direct interaction X 2 O75674 Q00610 affinity chromatography technology 17785434 physical association X 2 O75674 Q00610 affinity chromatography technology 17785434 physical association X 2 O75674 Q16512-3 biochemical 22939629 colocalization X 2 O75674 P49588 biochemical 22863883 colocalization X 2 O75674 O15144 biochemical 22863883 colocalization X 2 O75674 Q9GZT8-3 biochemical 22863883 colocalization X 2 O75674 O15294-3 biochemical 22863883 colocalization X 2 O75674 P59998-4 biochemical 22863883 colocalization X 2 O75674 Q99933 biochemical 22863883 colocalization X 2 O75674 Q9NPF4 biochemical 22863883 colocalization X 2 O75674 P23497-7 biochemical 22863883 colocalization X 2 O75674 P51692 biochemical 22863883 colocalization X 2 O75674 Q96S44 biochemical 22863883 colocalization X 2 O75674 O75312 biochemical 22863883 colocalization X 2 O75674 Q69YN2 two hybrid 16169070 direct interaction X 2 O75674 O14832 two hybrid 16169070 direct interaction X 2 O75674 Q92879-4 two hybrid 16169070 direct interaction X 2 O75674 P06241-3 pull down 11711534 direct interaction X 2 O75674 Q99759 two hybrid 21900206 direct interaction X 2 Q6FIE9 O75674 affinity chromatography technology 16412388 physical association X 2 Q6FIE9 O75674 two hybrid 21988832 direct interaction X 2 Q6FIE9 O75674 pull down 15047686 direct interaction X 2 Q6FIE9 O75674 two hybrid 20936779 direct interaction X 2 Q6FIE9 O75674 affinity chromatography technology 21903422 physical association X 2 O75718 O75674 biochemical 22863883 colocalization X 2 P13716 O75674 biochemical 22863883 colocalization X 2 P0CH28 O75674 pull down 20150893 direct interaction X 2 A8K031 O75674 two hybrid 16169070 direct interaction X 2 Q86TI2-2 O75674 biochemical 22863883 colocalization X 2 P49448 O75674 two hybrid 16169070 - X 2 P49448 O75674 two hybrid 16169070 - X 2 Q96A33 O75674 two hybrid 16169070 - X 2 Q96A33 O75674 two hybrid 16169070 - X 2 O75674 P62993-2 in vitro 11711534,12345679 - X 2 O75674 P62993-2 in vivo 11711534,12345679 - X 2 O75674 two hybrid 16169070 - X 2 O75674 P27986 in vitro 11711534 - X 2 O75674 Q15269 two hybrid 16169070 - X 2 O75674 O14832-2 two hybrid 16169070 - X 2 O75674 O14964 two hybrid 15611048 - X 2 O75674 P27986 in vitro 11711534 - X 2 O75674 Q9UBW8 two hybrid 16169070 - X 2 O75674 O14964 two hybrid 15611048 - X 2 O75674 two hybrid 16169070 - X 2 O75674 Q15269 two hybrid 16169070 - X 2 O75674 O14832-2 two hybrid 16169070 - X 2 O75674 Q8IZL8 two hybrid 16169070 - X 2 O75674 P62993-2 in vitro 11711534,12345679 - X 2 O75674 P62993-2 in vivo 11711534,12345679 - X 2 O75674 Q86YL7-5 two hybrid 16169070 - X 2 O75674 Q92575 two hybrid 16169070 - X 2 O75674 Q8IZL8 two hybrid 16169070 - X 2 O75674 Q86YL7-5 two hybrid 16169070 - X 2 O75674 Q9UBW8 two hybrid 16169070 - X 2 O75674 Q92575 two hybrid 16169070 - X 2 Q15155 O75674 two hybrid 16169070 - X 2 Q15155 O75674 two hybrid 16169070 - X 2 Q9UK61-2 O75674 two hybrid 16169070 - X 2 Q9UK61-2 O75674 two hybrid 16169070 - X 2 O75674 two hybrid 11711534 - X 2 O75674 in vitro 11711534 - X 2 O75674 P31943 two hybrid 16169070 - X 2 O75674 Q92879-2 two hybrid 16169070 - X 2 O75674 Q99816 two hybrid 15611048 - X 2 O75674 Q9NP72 two hybrid 16169070 - X 2 O75674 P31943 two hybrid 16169070 - X 2 O75674 Q9NP72 two hybrid 16169070 - X 2 O75674 Q69YN2 two hybrid 16169070 - X 2 O75674 two hybrid 11711534 - X 2 O75674 in vitro 11711534 - X 2 O75674 Q99816 two hybrid 15611048 - X 2 O75674 Q92879-2 two hybrid 16169070 - X 2 O75674 Q69YN2 two hybrid 16169070 - X 2 Q6FIE9 O75674 in vitro 15047686 - X 2 Q6FIE9 O75674 in vitro 15047686 - X 2 A8K031 O75674 two hybrid 16169070 - X 2 A8K031 O75674 two hybrid 16169070 - X 2 O75674 anti tag coimmunoprecipitation 21903422 association C 19 P49448 O75674 two hybrid pooling approach 16169070 physical association X 2 Q96A33 O75674 two hybrid pooling approach 16169070 physical association X 2 O75674 O14964 two hybrid 15611048 physical association X 2 O75674 P06396 two hybrid pooling approach 16169070 physical association X 2 O75674 Q8IZL8 two hybrid pooling approach 16169070 physical association X 2 O75674 Q9UBW8 two hybrid pooling approach 16169070 physical association X 2 O75674 Q92879 two hybrid pooling approach 16169070 physical association X 2 O75674 Q92575 two hybrid pooling approach 16169070 physical association X 2 O75674 Q15269 two hybrid pooling approach 16169070 physical association X 2 O75674 P52735 anti tag coimmunoprecipitation 18654987 physical association X 2 O75674 P52735 two hybrid 18654987 physical association X 2 O75674 B0LPF3 pull down 19798056 physical association X 2 O75674 P00533 anti bait coimmunoprecipitation 19798056 physical association X 2 O75674 P00533 anti bait coimmunoprecipitation 19798056 physical association X 2 O75674 P00533 anti bait coimmunoprecipitation 19798056 physical association X 2 O75674 B0LPF3 anti bait coimmunoprecipitation 19798056 physical association X 2 O75674 P00533 fluorescence microscopy 19798056 colocalization X 2 O75674 P00533 anti tag coimmunoprecipitation 19798056 physical association X 2 O75674 P00533 anti tag coimmunoprecipitation 19798056 physical association X 2 O75674 P0CG53 surface plasmon resonance 20150893 direct interaction X 2 Q9UKV5 O75674 two hybrid 21900206 physical association X 2 P55072 O75674 two hybrid 21900206 physical association X 2 Q15155 O75674 two hybrid pooling approach 16169070 physical association X 2 Q9UK61 O75674 two hybrid pooling approach 16169070 physical association X 2 P68363 O75674 two hybrid 21900206 physical association X 2 O75674 Q99816 two hybrid 15611048 physical association X 2 O75674 Q69YN2 two hybrid pooling approach 16169070 physical association X 2 O75674 P31943 two hybrid pooling approach 16169070 physical association X 2 O75674 Q9NP72 two hybrid pooling approach 16169070 physical association X 2 O75674 O14832 two hybrid pooling approach 16169070 physical association X 2 O75674 Q86YL7 two hybrid pooling approach 16169070 physical association X 2 O75674 Q00610 pull down 19798056 direct interaction X 2 O75674 Q00610 pull down 19798056 direct interaction X 2 O75674 O60784 pull down 19798056 physical association X 2 O75674 Q15075 fluorescence microscopy 19798056 colocalization X 2 O75674 O60784 pull down 19798056 physical association X 2 O75674 Q00610 pull down 19798056 physical association X 2 O75674 Q00610 pull down 19798056 physical association X 2 O75674 Q99759 two hybrid 21900206 physical association X 2 Q6FIE9 O75674 two hybrid pooling approach 20936779 physical association X 2 Q6FIE9 O75674 two hybrid array 21988832 physical association X 2 A8K031 O75674 two hybrid pooling approach 16169070 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B TOM1L1 NIF3L1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_301378 bait prey TOM1L1 EGFR MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0096(pull down)|MI:0007(anti tag coimmunoprecipitation)|MI:0096(pull down)|MI:0096(pull down)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 10,19798056 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint) BIOGRID_218149|BIOGRID_218148|MINT_46814|MINT_46815|MINT_46816|MINT_46817|MINT_46812|MINT_46813|UniProt_103983|MINT_78549|UniProt_103985|UniProt_103986|MINT_78551|MINT_78550|UniProt_103980|UniProt_103981|UniProt_103982|MINT_78554|MINT_78553|MINT_78552 prey|bait|bait|prey|prey|neutral component|bait|bait|prey|bait|bait|bait|bait|bait|neutral component|bait|prey|neutral component|prey|prey bait|prey|prey|bait|bait|neutral component|prey|prey|bait|prey|prey|prey|prey|prey|neutral component|prey|bait|neutral component|bait|bait TOM1L1 PDPN MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0468(hprd)|MI:0471(mint)|MI:0471(mint) BIOGRID_94025|UniProt_156599|HPRD_29432|MINT_35035|MINT_64012 prey|prey|-|prey|prey bait|bait|-|bait|bait TOM1L1 TOLLIP MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0397(two hybrid array)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 15047686,16412388,20936779,21903422,21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0914(association)|MI:0914(association) (biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(intact)|(biogrid)|MI:0468(hprd)|(intact)|(intact) BIOGRID_195241|BIOGRID_155833|UniProt_118190|BIOGRID_194906|BIOGRID_288569|UniProt_110777|BIOGRID_126969|HPRD_13245|UniProt_172494|UniProt_115752 bait|prey|unspecified role|bait|prey|prey|prey|-|prey|prey prey|bait|unspecified role|prey|bait|bait|bait|-|bait|bait TOM1L1 SP100 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304400 prey bait TOM1L1 SRC MI:0096(pull down)|MI:0096(pull down) 17785434 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_220899|BIOGRID_220898 bait|prey prey|bait TOM1L1 DPP9 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304394 prey bait TOM1L1 ALAD MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304390 prey bait TOM1L1 CELF1 MI:0007(anti tag coimmunoprecipitation)|MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0468(hprd)|(biogrid)|MI:0471(mint)|MI:0471(mint) UniProt_154593|HPRD_21664|BIOGRID_95064|MINT_35430|MINT_64458 prey|-|prey|prey|prey bait|-|bait|bait|bait TOM1L1 CCDC47 MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0915(physical association) (intact)|(biogrid)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint) UniProt_156171|BIOGRID_93601|MINT_64499|HPRD_29433|MINT_35471 prey|prey|prey|-|prey bait|bait|bait|-|bait TOM1L1 UBXN4 MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(intact)|(biogrid) MINT_34510|HPRD_29434|MINT_63466|UniProt_156664|BIOGRID_94089 prey|-|prey|prey|prey bait|-|bait|bait|bait TOM1L1 TP53RK MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304403 prey bait ARPC2 TOM1L1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_298578 prey bait TOM1L1 GLUD2 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(intact) BIOGRID_93603|MINT_33941|HPRD_28570|MINT_62883|UniProt_156173 prey|prey|-|prey|prey bait|bait|-|bait|bait TOM1L1 AARS MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_298184 bait prey TOM1L1 VAV2 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 18654987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(intact)|(biogrid)|(biogrid) UniProt_96798|UniProt_96863|BIOGRID_184844|BIOGRID_184895 prey|prey|prey|prey bait|bait|bait|bait TOM1L1 GSN MI:0018(two hybrid)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_34665|MINT_63635 prey|prey bait|bait PHYH TOM1L1 MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|- MI:0471(mint)|(intact)|MI:0471(mint)|(biogrid)|MI:0468(hprd) MINT_62183|UniProt_156401|MINT_33242|BIOGRID_93828|HPRD_28976 bait|bait|bait|bait|- prey|prey|prey|prey|- TOM1L1 STAT5B MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304401 prey bait OGT TOM1L1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_301607 prey bait TOM1L1 ARPC4 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304391 prey bait TOM1L1 MAP3K3 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_158250|UniProt_158927|UniProt_179525 prey|prey|prey bait|bait|bait TOM1L1 BAG1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304392 prey bait TOM1L1 GSN MI:0492(in vitro)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(intact) HPRD_28194|BIOGRID_94402|UniProt_155332 -|prey|prey -|bait|bait TOM1L1 TSG101 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15611048 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(biogrid)|(biogrid) UniProt_81028|MINT_31200|HPRD_9035|MINT_59796|BIOGRID_192407|BIOGRID_192408 bait|bait|-|bait|prey|bait prey|prey|-|prey|bait|prey TOM1L1 FYN MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down) 11711534,20182632 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid) HPRD_34385|BIOGRID_210757|BIOGRID_210756|BIOGRID_110426 -|prey|bait|prey -|bait|prey|bait TOM1L1 PELP1 MI:0492(in vitro)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(intact)|(biogrid)|MI:0471(mint)|MI:0471(mint) HPRD_29428|UniProt_155566|BIOGRID_94629|MINT_62206|MINT_33265 -|prey|prey|prey|prey -|bait|bait|bait|bait TOM1L1 RAB18 MI:0018(two hybrid)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_63725|MINT_34755 prey|prey bait|bait TOM1L1 AMFR MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_178459|UniProt_157861|BIOGRID_158567 prey|prey|prey bait|bait|bait TOM1L1 FAM208A MI:0018(two hybrid)|MI:0492(in vitro)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0468(hprd)|(intact)|MI:0471(mint) MINT_65490|HPRD_29429|UniProt_157122|MINT_36374 prey|-|prey|prey bait|-|bait|bait ZNF259 TOM1L1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304404 bait prey ARPC5 TOM1L1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_298612 prey bait TOM1L1 GRB2 MI:0096(pull down)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0096(pull down)|MI:0492(in vitro)|MI:0096(pull down)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 10,11711534,19798056 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0468(hprd)|(intact)|MI:0471(mint)|MI:0471(mint) BIOGRID_110427|MINT_78557|MINT_78556|UniProt_103984|HPRD_4475|UniProt_103971|MINT_46819|MINT_46820 prey|prey|prey|prey|-|prey|prey|prey bait|bait|bait|bait|-|bait|bait|bait TOM1L1 UBC MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15047686,21139048,21890473,21906983,22053931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_171374|BIOGRID_180541|BIOGRID_176451|BIOGRID_222549|BIOGRID_195239 prey|prey|prey|prey|bait bait|bait|bait|bait|prey TOM1L1 COPS7A MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0468(hprd)|(biogrid)|MI:0471(mint)|(intact) MINT_65429|HPRD_22455|BIOGRID_95048|MINT_36313|UniProt_154576 prey|-|prey|prey|prey bait|-|bait|bait|bait TOM1L1 METTL1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304397 prey bait TOM1L1 PKN1 MI:0401(biochemical) 22939629 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_240239 prey bait TOM1L1 HNRNPH1 MI:0492(in vitro)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|MI:0471(mint)|(intact)|MI:0471(mint) HPRD_28815|MINT_34819|UniProt_156919|MINT_63789 -|prey|prey|prey -|bait|bait|bait TOM1L1 LEPRE1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304396 prey bait TOM1L1 CRTAP MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304393 prey bait HGS TOM1L1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15611048 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0468(hprd)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint) UniProt_81029|HPRD_27528|BIOGRID_192410|BIOGRID_192409|MINT_31201|MINT_59797 bait|-|bait|prey|bait|bait prey|-|prey|bait|prey|prey NDC80 TOM1L1 MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0468(hprd)|(biogrid)|MI:0471(mint)|(intact) MINT_33238|HPRD_29427|BIOGRID_94481|MINT_62179|UniProt_155413 bait|-|bait|bait|bait prey|-|prey|prey|prey TOM1L1 RPRD1B MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_303203 bait prey TOM1L1 RAB18 MI:0492(in vitro)|MI:0007(anti tag coimmunoprecipitation) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(intact) HPRD_29426|UniProt_157108 -|prey -|bait TOM1L1 OSGEP MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304398 prey bait TOM1L1 PIK3R1 MI:0492(in vitro) 11711534 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_776 - - TOM1L1 ACTR2 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304389 prey bait TOM1 TOM1L1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0096(pull down)|MI:0096(pull down) 10,19798056 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact) MINT_78559|MINT_78558|MINT_46822|MINT_46821|UniProt_103972|UniProt_103973 bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|prey ARPC1B TOM1L1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_298561 prey bait TOM1L1 TUBA1B MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_178339|UniProt_157741|BIOGRID_156294 prey|prey|prey bait|bait|bait TOM1L1 HSPBP1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304395 prey bait TOM1L1 PPME1 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304399 prey bait TOM1L1 VCP MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 21900206 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_157902|UniProt_157816|UniProt_178414 prey|prey|prey bait|bait|bait TOM1L1 PWP2 MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0468(hprd)|(biogrid)|MI:0471(mint) UniProt_156458|MINT_63375|HPRD_28881|BIOGRID_93885|MINT_34419 prey|prey|-|prey|prey bait|bait|-|bait|bait TOM1L1 CWF19L1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(biogrid)|MI:0468(hprd)|(intact)|MI:0471(mint) MINT_36138|BIOGRID_93468|HPRD_29431|UniProt_156032|MINT_65254 prey|prey|-|prey|prey bait|bait|-|bait|bait TOM1L1 NOMO1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0492(in vitro)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact)|MI:0468(hprd)|MI:0471(mint) BIOGRID_94657|MINT_63373|UniProt_155596|HPRD_29430|MINT_34417 prey|prey|prey|-|prey bait|bait|bait|-|bait TOM1L1 EEA1 MI:0096(pull down)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 10,19798056 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization) (intact)|MI:0471(mint)|MI:0471(mint) UniProt_103979|MINT_46818|MINT_78555 neutral component|neutral component|neutral component neutral component|neutral component|neutral component TOM1L1 SURF2 MI:0401(biochemical) 22863883 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_304402 prey bait TOM1L1 CLTC MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0096(pull down)|MI:0096(pull down)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology) 10,16412388,17785434,19798056 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0403(colocalization)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(biogrid)|(biogrid) MINT_46824|MINT_78563|MINT_78564|MINT_78561|MINT_46827|BIOGRID_220896|BIOGRID_220888|MINT_78562|MINT_46826|MINT_46825|BIOGRID_218150|BIOGRID_219162|BIOGRID_219163|UniProt_103976|UniProt_103977|UniProt_103974|UniProt_103975|BIOGRID_219160|BIOGRID_219161|BIOGRID_194909 bait|bait|bait|bait|bait|prey|bait|bait|bait|bait|bait|bait|prey|bait|bait|bait|bait|bait|bait|bait prey|prey|prey|prey|prey|bait|prey|prey|prey|prey|prey|prey|bait|prey|prey|prey|prey|prey|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality ARPC1B TOM1L1 22863883 0401 HT ARPC2 TOM1L1 22863883 0401 HT OGT TOM1L1 22863883 0401 HT ARPC5 TOM1L1 22863883 0401 HT ZPR1 TOM1L1 22863883 0401 HT TOM1L1 CRTAP 22863883 0401 HT TOM1L1 FYN 20182632,11711534,11711534 0004,0018,0096 LC TOM1L1 AARS 22863883 0401 HT TOM1L1 STAT5B 22863883 0401 HT TOM1L1 ARPC4 22863883 0401 HT TOM1L1 ACTR2 22863883 0401 HT TOM1L1 GRB2 19798056,11711534,19798056 0006,0096,0096 LC TOM1L1 CLTC 17785434,17785434,16412388,19798056,17785434 0428,0004,0004,0096,0096 LC TOM1L1 SURF2 22863883 0401 HT TOM1L1 PKN1 22939629 0401 HT TOM1L1 P3H1 22863883 0401 HT TOM1L1 FLJ00340 22863883 0401 HT TOM1L1 Q6ZMU0 22863883 0401 HT TOM1L1 DPP9 22863883 0401 HT TOM1L1 TP53RK 22863883 0401 HT TOM1L1 BAG1 22863883 0401 HT TOM1L1 NIF3L1 22863883 0401 HT TOM1L1 TOLLIP 15047686,21903422,15047686,16412388,21903422 0004,0007,0096,0004,0004 LC TOM1L1 OSGEP 22863883 0401 HT TOM1L1 RPRD1B 22863883 0401 HT TOM1L1 HSPBP1 22863883 0401 HT TOM1L1 METTL1 22863883 0401 HT TOM1L1 PPME1 22863883 0401 HT ARPC1B TOM1L1 22863883 0401 HT ARPC2 TOM1L1 22863883 0401 HT OGT TOM1L1 22863883 0401 HT ARPC5 TOM1L1 22863883 0401 HT ZPR1 TOM1L1 22863883 0401 HT TOM1L1 CRTAP 22863883 0401 HT TOM1L1 AARS 22863883 0401 HT TOM1L1 STAT5B 22863883 0401 HT TOM1L1 ARPC4 22863883 0401 HT TOM1L1 ACTR2 22863883 0401 HT TOM1L1 SURF2 22863883 0401 HT TOM1L1 PKN1 22939629 0401 HT TOM1L1 P3H1 22863883 0401 HT TOM1L1 FLJ00340 22863883 0401 HT TOM1L1 Q6ZMU0 22863883 0401 HT TOM1L1 DPP9 22863883 0401 HT TOM1L1 TP53RK 22863883 0401 HT TOM1L1 BAG1 22863883 0401 HT TOM1L1 NIF3L1 22863883 0401 HT TOM1L1 OSGEP 22863883 0401 HT TOM1L1 RPRD1B 22863883 0401 HT TOM1L1 HSPBP1 22863883 0401 HT TOM1L1 METTL1 22863883 0401 HT TOM1L1 PPME1 22863883 0401 HT TOM1L1 FYN 20182632,11711534,11711534 0004,0018,0096 LC TOM1L1 GRB2 19798056,11711534,19798056 0006,0096,0096 LC TOM1L1 CLTC 17785434,17785434,16412388,19798056,17785434 0428,0004,0004,0096,0096 LC TOM1L1 TOLLIP 15047686,21903422,15047686,16412388,21903422 0004,0007,0096,0004,0004 LC KNTC2 TOM1L1 16169070,16169070 0018,0398 HT NDC80 TOM1L1 16169070,16169070 0018,0398 HT PHYH TOM1L1 16169070,16169070 0018,0398 HT HGS TOM1L1 15611048 0018 LC ARPC1B TOM1L1 22863883 0401 LC ARPC2 TOM1L1 22863883 0401 LC OGT TOM1L1 22863883 0401 LC ARPC5 TOM1L1 22863883 0401 LC ZPR1 TOM1L1 22863883 0401 LC TOM1L1 TOM1L1 PDB_3RRU 0114 LC TOM1L1 CRTAP 22863883 0401 LC TOM1L1 EGFR 19798056,19798056,19798056,19798056 0004,0006,0416,0007 LC TOM1L1 FYN 11711534,11711534 0018,0096 LC TOM1L1 GSN 16169070,16169070 0018,0398 HT TOM1L1 HNRNPH1 16169070,16169070 0018,0398 HT TOM1L1 GLUD2 16169070,16169070 0018,0398 HT TOM1L1 AARS 22863883 0401 LC TOM1L1 STAT5B 22863883 0401 LC TOM1L1 VAV2 18654987,18654987,18654987 0007,0004,0018 HT TOM1L1 VCP 21900206 0018 HT TOM1L1 ARPC4 22863883 0401 LC TOM1L1 ACTR2 22863883 0401 LC TOM1L1 TUBA1B 21900206 0018 HT TOM1L1 EEA1 19798056 0416 LC TOM1L1 NOMO1 16169070,16169070 0018,0398 HT TOM1L1 PWP2 16169070,16169070 0018,0398 HT TOM1L1 SURF2 22863883 0401 LC TOM1L1 PKN1 22939629 0401 LC TOM1L1 P3H1 22863883 0401 LC TOM1L1 CWF19L1 16169070,16169070 0018,0398 HT TOM1L1 FLJ00340 22863883 0401 LC TOM1L1 Q6ZMU0 22863883 0401 LC TOM1L1 DPP9 22863883 0401 LC TOM1L1 PDPN 16169070,16169070 0018,0398 HT TOM1L1 PELP1 16169070,16169070 0018,0398 HT TOM1L1 UBXN4 16169070,16169070 0018,0398 HT TOM1L1 CELF1 16169070,16169070 0018,0398 HT TOM1L1 CCDC47 16169070,16169070 0018,0398 HT TOM1L1 TP53RK 22863883 0401 LC TOM1L1 MAP3K3 21900206 0018 HT TOM1L1 TSG101 15611048 0018 LC TOM1L1 BAG1 22863883 0401 LC TOM1L1 NIF3L1 22863883 0401 LC TOM1L1 TOLLIP 20936779,21988832,20936779,21988832 0398,0397,0018,0018 HT TOM1L1 RAB18 16169070,16169070 0018,0398 HT TOM1L1 OSGEP 22863883 0401 LC TOM1L1 RPRD1B 22863883 0401 LC TOM1L1 HSPBP1 22863883 0401 LC TOM1L1 METTL1 22863883 0401 LC TOM1L1 COPS7A 16169070,16169070 0018,0398 HT TOM1L1 FAM208A 16169070,16169070 0018,0398 HT TOM1L1 AMFR 21900206 0018 HT TOM1L1 PPME1 22863883 0401 LC TOM1L1 HEL-S-70 21900206 0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID O75674 O14777 TOM1L1 NDC80 0.286 16169070 P59998 O75674 ARPC4 TOM1L1 0.081 22863883 O75674 O14832 TOM1L1 PHYH 0.286 16169070 O75674 O14964 TOM1L1 HGS 0.671 15611048 P61160 O75674 ACTR2 TOM1L1 0.081 22863883 P23497 O75674 SP100 TOM1L1 0.081 22863883 Q8IZL8 O75674 PELP1 TOM1L1 0.286 16169070 Q9NPF4 O75674 OSGEP TOM1L1 0.081 22863883 O75674 O60784 TOM1L1 TOM1 0.376 19798056 Q9NZL4 O75674 HSPBP1 TOM1L1 0.081 22863883 O75674 O75312 TOM1L1 ZPR1 0.081 22863883 Q9Y570 O75674 PPME1 TOM1L1 0.081 22863883 O75674 O15143 TOM1L1 ARPC1B 0.081 22863883 O75674 O15144 TOM1L1 ARPC2 0.081 22863883 O75674 O15294 TOM1L1 OGT 0.081 22863883 O75674 O15511 TOM1L1 ARPC5 0.081 22863883 P06241 O75674 FYN TOM1L1 0.569 11711534,20182632 P06396 O75674 GSN TOM1L1 0.286 16169070 P0CH28 O75674 UBC TOM1L1 0.309 20150893 P12931 O75674 SRC TOM1L1 0.376 17785434 P31943 O75674 HNRNPH1 TOM1L1 0.126 16169070 P49588 O75674 AARS TOM1L1 0.081 22863883 P52735 O75674 VAV2 TOM1L1 0.554 18654987 Q69YN2 O75674 CWF19L1 TOM1L1 0.286 16169070 Q86YL7 O75674 PDPN TOM1L1 0.286 16169070 Q9NP72 O75674 RAB18 TOM1L1 0.126 16169070 Q9NQG5 O75674 RPRD1B TOM1L1 0.081 22863883 Q9UK61 O75674 FAM208A TOM1L1 0.126 16169070 O75718 O75674 CRTAP TOM1L1 0.081 22863883 P0CG53 O75674 UBB TOM1L1 0.309 20150893 Q86TI2 O75674 DPP9 TOM1L1 0.081 22863883 Q88489 O75674 Q88489 TOM1L1 0.126 22014111 P13716 O75674 ALAD TOM1L1 0.081 22863883 P00533 O75674 EGFR TOM1L1 0.659 19798056 Q99759 O75674 MAP3K3 TOM1L1 0.332 21900206 P68363 O75674 TUBA1B TOM1L1 0.332 21900206 P59910 O75674 DNAJB13 TOM1L1 0.236 unassigned1304 P62993 O75674 GRB2 TOM1L1 0.569 19798056,11711534 Q9H0E2 O75674 TOLLIP TOM1L1 0.765 20936779,16412388,unassigned1304,21903422,21988832 Q00610 O75674 CLTC TOM1L1 0.922 19798056,16412388,17785434 Q92879 O75674 CELF1 TOM1L1 0.286 16169070 Q96A33 O75674 CCDC47 TOM1L1 0.286 16169070 Q91NH1 O75674 Q91NH1 TOM1L1 0.126 22014111 Q92575 O75674 UBXN4 TOM1L1 0.286 16169070 Q96S44 O75674 TP53RK TOM1L1 0.081 22863883 Q99933 O75674 BAG1 TOM1L1 0.081 22863883 Q99816 O75674 TSG101 TOM1L1 0.671 15611048 Q9UBP6 O75674 METTL1 TOM1L1 0.081 22863883 Q9UBW8 O75674 COPS7A TOM1L1 0.286 16169070 Q9UKV5 O75674 AMFR TOM1L1 0.332 21900206 P49448 O75674 GLUD2 TOM1L1 0.286 16169070 Q15075 O75674 EEA1 TOM1L1 0.126 19798056 Q15155 O75674 NOMO1 TOM1L1 0.286 16169070 Q15269 O75674 PWP2 TOM1L1 0.286 16169070 Q15527 O75674 SURF2 TOM1L1 0.081 22863883 P51692 O75674 STAT5B TOM1L1 0.081 22863883 Q16512 O75674 PKN1 TOM1L1 0.081 22939629 Q32P28 O75674 LEPRE1 TOM1L1 0.081 22863883 P55072 O75674 VCP TOM1L1 0.332 21900206

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 NDC80 TOM1L1 MI:0045 experimental interaction detection MI:0461 interaction database PHYH TOM1L1 MI:0045 experimental interaction detection MI:0461 interaction database HGS TOM1L1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1 TOM1L1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 EGFR MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 FYN MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 GSN MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 UBB MI:0362 inference MI:0461 interaction database TOM1L1 UBC MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 SRC MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 HNRNPH1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 GLUD2 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 VAV2 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 VCP MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 GRB2 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 TUBA1B MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 CLTC MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 NOMO1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 PWP2 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 CWF19L1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 PDPN MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 PELP1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 CELF1 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 CCDC47 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 MAP3K3 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 TSG101 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 TOLLIP MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 RAB18 MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 COPS7A MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 FAM208A MI:0045 experimental interaction detection MI:0461 interaction database TOM1L1 AMFR MI:0045 experimental interaction detection MI:0461 interaction database