PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus MAK ANAPC11 21988832 biogrid,intact exp P P P P P P P P P P P P P P P P P P P GP PTTG1 ANAPC11 10922056,12956947,11739784 biogrid exp GP G G G GP G G G GP G G G G GP G GP G G G G GP G G G GP GP G GP G UBE2U ANAPC11 19690564 biogrid,intact exp P P P P P P P P P P P P P P P P P P P GP MLKL ANAPC11 21988832 biogrid,intact exp G G G G G G G GP G G GP G GP G G GP G G GP G G G G G GP G G GP G ANAPC11 CAPN11 21988832 biogrid,intact exp P G GP TRIM65 ANAPC11 22493164 biogrid,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G NKD2 ANAPC11 21988832 biogrid,intact exp G GP G P GP G GP GP G GP G G GP G GP GP G GP P GP GP GP GP G GP G G RNF111 ANAPC11 22493164 biogrid,intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G BIRC6 ANAPC11 24302728 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CCNA2 ANAPC11 24302728 biogrid exp G G G G GP G G G GP G G G G GP G GP G G G G G G G GP GP GP GP ZAP70 ANAPC11 21988832 biogrid,intact exp G G GP G G G GP G G GP G E2F1 ANAPC11 25368385 biogrid exp P GP G G GP GP G GP GP G GP G GP GP GP GP GP GP G P P GP P GP P GP GP G UBE2K ANAPC11 24930963,18662541,17632060 biogrid exp, ortho GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC11 ANAPC11 10922056,11739784 hprd,biogrid exp, ortho GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2C ANAPC11 25959309,25161877,23708605,25825779,23708001,17360335,23078409,21874044,23288039,22580460,23972993,25490258,23670162,17227951,22529100,16455800,18662541,25246557,23707760,25043029,11739784,19826003,20080579,22205987,22193957,20733055,23791783,21937719, 25402006, 23023127 hprd,biogrid exp, ortho, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC11 CDC23 24163370, 25402006, 21836163 biogrid exp, ortho, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CDC16 ANAPC11 24163370,11739784,20360068, 25402006, 21836163 hprd,biogrid,intact exp, ortho, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G UBE2D2 ANAPC11 25161877,24930963,15256223,12956947,11739784,20383333,19826003, 23023127 biogrid exp, ortho, pred GP G G G GP GP G G GP G GP G GP GP G G GP GP GP G GP GP G GP G GP GP GP G ANAPC11 FZR1 18662541,12956947, 25402006 biogrid exp, pred G GP G G G GP G GP GP G GP G GP G G GP GP G P G G GP G GP GP G GP GP G CUL5 ANAPC11 10230407, 23023127 biogrid exp, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CCNB1 ANAPC11 23708605, 25402006 biogrid exp, pred P G G GP G G G GP G P GP GP G G G G GP G P GP P GP GP CDC20 ANAPC11 25241761,18997788, 25402006, 21836163 biogrid,intact exp, pred P G GP G GP P P GP G G P GP P GP GP ANAPC11 ANAPC2 24163370,10230407,12956947,11739784, 25402006, 23023127 hprd,biogrid exp, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP GP GP GP G UBE2S ANAPC11 25490258,23708605,22529100,25825779,23708001,25043029,20080579,23288039,23972993, 25402006, 23023127 biogrid exp, pred G G G G G G G G GP G G G GP G G G G G G G G G G G GP G UBE2D1 ANAPC11 25825779,19475398,19826003,20080579, 25402006, 23023127 biogrid exp, pred GP G G G GP GP G G GP G GP G GP GP G G GP GP GP G GP GP G GP G GP GP GP G ANAPC11 FBXO5 16921029, 25402006 biogrid exp, pred P P G GP P P GP P P P GP P GP P P P P P GP GP P P ANAPC11 ANAPC10 11739784, 25402006, 23023127, 21836163 hprd,biogrid exp, pred GP G G G GP GP G GP GP G GP G GP GP G GP GP G GP G G GP GP GP GP GP GP GP G ANAPC11 ANAPC4 25490258,26083744,21926987,12956947,25043029,23078409, 25402006, 21836163 biogrid exp, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CDC27 ANAPC11 14657031,10922056,16364912,24163370,12956947, 25402006, 21836163 biogrid exp, pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HSPA9 ANAPC11 ortho GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HSPA4 ANAPC11 ortho GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PKM ANAPC11 ortho GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP GP GP GP G GMPS ANAPC11 ortho G G G G GP GP G G G G G G G G G G GP G G G G G G G G G G GP G HGS ANAPC11 ortho GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP GP GP G GP GP G CNBP ANAPC11 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FBXO43 ANAPC11 ortho P P G GP P P GP P P P P P P P P P GP PLK1 ANAPC11 23023127 ortho, pred P P G G GP P G GP GP P P GP GP GP GP GP G GP P GP GP GP P P GP PCBP2 ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CKS2 ANAPC11 23023127 pred GP GP G GP P G GP GP GP G GP GP G GP P GP P GP GP P P GP GP GP GP G UBE2L6 ANAPC11 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G PSMC1 ANAPC11 21836163 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G PSMA4 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G APC2 ANAPC11 25402006 pred G G G G G G G G G G G G G PSMB2 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G PSMB5 ANAPC11 21836163 pred G GP G G G GP G G GP G GP G G G G G GP G GP G G G GP G G G GP GP G CKS1B ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2NL ANAPC11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ANAPC1 ANAPC11 25402006 pred P P P P P P P P P P P P P P P P P P P ANAPC11 UBE2D4 25402006, 23023127 pred GP G G G GP GP G G GP G GP G GP GP G G GP GP GP G GP GP G GP G GP GP GP G UBE2G2 ANAPC11 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP G G GP GP GP GP G PSMB10 ANAPC11 21836163 pred GP G G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP G G GP GP GP G G PSMD8 ANAPC11 21836163 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMC2 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2H ANAPC11 23023127 pred GP GP G G GP GP G GP G G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CUL4A ANAPC11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CDH1 ANAPC11 25402006 pred GP G G G GP GP G GP G G GP G GP G GP GP GP GP G GP G CUL2 ANAPC11 23023127 pred GP GP G G G GP G G GP G GP G GP GP G G GP GP GP G GP GP GP G G G GP GP G RING1 ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2B ANAPC11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2F ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G UBE2V1 ANAPC11 23023127 pred ANAPC11 TRAF6 23023127 pred GP GP G G GP G G GP GP G GP G GP G G GP G GP G G GP GP GP G GP GP GP GP G RNF167 ANAPC11 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP GP GP G GP GP G G GP G GP GP G PSMA2 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G PSMC4 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC13 ANAPC11 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G SRP14 ANAPC11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CDC34 ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC11 ANAPC5 25402006, 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PIN1 ANAPC11 25402006 pred G GP G G GP GP G G GP G G G G GP G G GP G P G P GP G G G G GP GP G ANAPC11 PSMD13 23023127, 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G CUL4B ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G G GP G GP GP G GP G GP GP GP GP GP GP GP GP G RNFT1 ANAPC11 23023127 pred GP GP G GP P G GP GP P G GP GP G GP P GP P G P GP GP GP GP GP GP GP PSME3 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MAD2L1 ANAPC11 25402006 pred P G G P P GP P P GP G GP P G P P GP P GP GP GP GP PSMA5 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RAD18 ANAPC11 23023127 pred P P P GP P P G P P GP P UBE2I ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G SKP1 ANAPC11 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G PSMB1 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMD3 ANAPC11 23023127, 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMA6 ANAPC11 21836163 pred P P P P P P P P P P P P P P P P P P P ANAPC16 ANAPC11 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PLAT ANAPC11 23023127 pred G G G G GP GP G G G G GP G G GP G G GP G GP G GP G GP G G GP G G G UFD1L ANAPC11 23023127 pred G GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP GP G GP GP G G GP G UBE2D3 ANAPC11 25402006, 23023127 pred GP G G G GP GP G G GP G GP G GP GP G G GP GP GP G GP GP G GP G GP GP GP G UBE2L3 ANAPC11 23023127 pred GP G G G G GP G GP GP G GP G G G G GP GP G GP G G G GP GP GP G GP GP G PSMA7 ANAPC11 21836163 pred G GP G G G GP G G GP G GP G G G G GP GP G GP G GP G G G GP G GP GP G RBX1 ANAPC11 23023127 pred G G G G G GP G GP G G G G GP G G G GP G GP G GP GP G G G G G GP G PSMB8 ANAPC11 21836163 pred SUMO2 ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBE2N ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G RNF5 ANAPC11 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G TRIM21 ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMB6 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TIA1 ANAPC11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSMB4 ANAPC11 21836163 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP G G GP GP GP GP G BUB1B ANAPC11 25402006 pred P P G GP P GP GP P P GP GP P GP P GP P P P GP P GP GP G UBE2A ANAPC11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TGFB1I1 ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G UBE2E1 ANAPC11 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G CDC26 ANAPC11 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G G GP GP GP GP GP GP GP G PSMB3 ANAPC11 23023127, 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSMD1 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC11 MAD2L2 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G ANAPC11 PSME2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ANAPC11 HDAC6 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G BMI1 ANAPC11 23023127 pred P P P P P P P P P P P P P P P P P P P P P CAND1 ANAPC11 23023127 pred G GP G G G G G G GP G GP G G G G GP G GP G G G G GP GP GP G G GP G UBE2E3 ANAPC11 23023127 pred GP GP G G G GP G G GP G GP G G GP G GP GP GP G G GP G G GP GP G GP GP G UBE2M ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G BRCA1 ANAPC11 23023127 pred P P G GP P P P P P P GP P P P P P P P P P P GP RNF135 ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G UBE2E2 ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMD4 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP G GP GP G UBE2V2 ANAPC11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CUL3 ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RFWD3 ANAPC11 23023127 pred G G G G G G G G G G G G G G G G G G IGF2BP3 ANAPC11 23023127 pred P P P GP P P P P P P P P GP P P G P P P GP G RALA ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DTX3L ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G GP GP GP GP GP GP G UBE2T ANAPC11 23023127 pred G G G GP G GP P P P GP GP P GP P G GP P GP G PSMA1 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RAN ANAPC11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSMD9 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMA3 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP G GP G GP GP GP G GP G GP GP G UBE2G1 ANAPC11 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ANAPC11 ANAPC7 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G RNF4 ANAPC11 23023127 pred GP G G G G GP G GP GP G GP G G G G G GP GP G G GP GP GP GP G G GP GP G CUL1 ANAPC11 23023127 pred GP G G G G GP G GP GP G GP G GP G G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMD14 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP G G GP GP GP GP G GP G G GP GP G GP GP G PSMC3 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NEK2 ANAPC11 25402006 pred P G G P P GP P P GP P P P G P P GP P P GP CBX8 ANAPC11 23023127 pred P P P P P P P P P P P P P P P P P P P P CHFR ANAPC11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSMD11 ANAPC11 23023127, 21836163 pred G GP G G GP GP G GP GP G GP G GP G G G GP G G G GP G G G G G G GP G TRAF7 ANAPC11 23023127 pred GP GP G G G GP G GP GP G GP G GP G G GP GP G G G G G GP GP GP G GP GP G PSMB7 ANAPC11 21836163 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9UJX5 Q9NYG5 biochemical 23078409 association X 2 Q9UJX5 Q9NYG5 biochemical 25043029 association X 2 Q9UJX5 Q9NYG5 affinity chromatography technology 21926987 physical association X 2 Q9NYG5 two hybrid 21988832 direct interaction X 2 Q9NYG5 Q9NYG5 enzymatic study 10922056 direct interaction X 2 Q9NYG5 Q9NYG5 enzymatic study 11739784 direct interaction X 2 P62837 Q9NYG5 affinity chromatography technology 15256223 physical association X 2 P62837 Q9NYG5 pull down 19826003 direct interaction X 2 P62837 Q9NYG5 pull down 24930963 direct interaction X 2 P62837 Q9NYG5 pull down 20383333 direct interaction X 2 P62837 Q9NYG5 pull down 25161877 direct interaction X 2 P62837 Q9NYG5 pull down 11739784 direct interaction X 2 P62837 Q9NYG5 pull down 11739784 direct interaction X 2 Q8R349 Q9NYG5 affinity chromatography technology 20360068 physical association X 2 Q93034 Q9NYG5 two hybrid 10230407 direct interaction X 2 Q9NR09 Q9NYG5 affinity chromatography technology 24302728 physical association X 2 O00762 Q9NYG5 pull down 20080579 direct interaction X 2 O00762 Q9NYG5 pull down 17227951 direct interaction X 2 O00762 Q9NYG5 pull down 21937719 direct interaction X 2 O00762 Q9NYG5 pull down 17360335 direct interaction X 2 O00762 Q9NYG5 pull down 20733055 direct interaction X 2 O00762 Q9NYG5 pull down 16455800 direct interaction X 2 O00762 Q9NYG5 pull down 22580460 direct interaction X 2 O00762 Q9NYG5 pull down 19826003 direct interaction X 2 O00762 Q9NYG5 pull down 22529100 direct interaction X 2 O00762 Q9NYG5 pull down 21874044 direct interaction X 2 O00762 Q9NYG5 pull down 23078409 direct interaction X 2 O00762 Q9NYG5 pull down 18662541 direct interaction X 2 O00762 Q9NYG5 pull down 23708001 direct interaction X 2 O00762 Q9NYG5 pull down 23708605 direct interaction X 2 O00762 Q9NYG5 pull down 23791783 direct interaction X 2 O00762 Q9NYG5 pull down 25043029 direct interaction X 2 O00762 Q9NYG5 pull down 22193957 direct interaction X 2 O00762 Q9NYG5 pull down 25161877 direct interaction X 2 O00762 Q9NYG5 pull down 23707760 direct interaction X 2 O00762 Q9NYG5 pull down 23670162 direct interaction X 2 O00762 Q9NYG5 pull down 25246557 direct interaction X 2 O00762 Q9NYG5 pull down 23288039 direct interaction X 2 O00762 Q9NYG5 pull down 22205987 direct interaction X 2 O00762 Q9NYG5 pull down 11739784 direct interaction X 2 P61086 Q9NYG5 pull down 18662541 direct interaction X 2 P61086 Q9NYG5 pull down 17632060 direct interaction X 2 P61086 Q9NYG5 pull down 24930963 direct interaction X 2 Q9UJX6 Q9NYG5 biochemical 24163370 association X 2 Q9UJX6 Q9NYG5 pull down 11739784 direct interaction X 2 Q9UJX6 Q9NYG5 pull down 11739784 direct interaction X 2 Q9UJX6 Q9NYG5 two hybrid 10230407 direct interaction X 2 Q13042-2 Q9NYG5 biochemical 24163370 association X 2 K7N7S0 Q9NYG5 enzymatic study 12234927 direct interaction X 2 Q9H1A4 Q9NYG5 pull down 12956947 direct interaction X 2 Q9UJX2 Q9NYG5 biochemical 24163370 association X 2 Q969F2 Q9NYG5 two hybrid 21988832 direct interaction X 2 Q12834 Q9NYG5 affinity chromatography technology 18997788 physical association X 2 O95997 Q9NYG5 enzymatic study 10922056 direct interaction X 2 O95997 Q9NYG5 enzymatic study 22193957 direct interaction X 2 O95997 Q9NYG5 enzymatic study 20080579 direct interaction X 2 O95997 Q9NYG5 enzymatic study 25161877 direct interaction X 2 O95997 Q9NYG5 enzymatic study 11739784 direct interaction X 2 Q6PJ69 Q9NYG5 two hybrid 22493164 direct interaction X 2 Q9UMQ6 Q9NYG5 two hybrid 21988832 direct interaction X 2 P14635 Q9NYG5 enzymatic study 23007861 direct interaction X 2 P14635 Q9NYG5 enzymatic study 22014574 direct interaction X 2 P14635 Q9NYG5 pull down 23708605 direct interaction X 2 P14635 Q9NYG5 enzymatic study 24163370 direct interaction X 2 P14635 Q9NYG5 enzymatic study 23288039 direct interaction X 2 P14635 Q9NYG5 enzymatic study 22193957 direct interaction X 2 P14635 Q9NYG5 enzymatic study 20080579 direct interaction X 2 P14635 Q9NYG5 enzymatic study 25161877 direct interaction X 2 P20794 Q9NYG5 two hybrid 21988832 direct interaction X 2 A0A024R1Z1 Q9NYG5 enzymatic study 23972993 direct interaction X 2 O95996 Q9NYG5 affinity chromatography technology 12956947 physical association X 2 Q9NYG5 affinity chromatography technology 16364912 physical association X 2 Q9NYG5 biochemical 24163370 association X 2 Q9NYG5 affinity chromatography technology 10922056 physical association X 2 Q9NYG5 affinity chromatography technology 12956947 physical association X 2 Q9NYG5 affinity chromatography technology 10922056 physical association X 2 Q9NYG5 affinity chromatography technology 14657031 physical association X 2 Q9NYG5 Q9UKT4-2 pull down 16921029 direct interaction X 2 Q9NYG5 Q8NB16 two hybrid 21988832 direct interaction X 2 Q9NYG5 two hybrid 19690564 direct interaction X 2 Q9UM13 Q9NYG5 pull down 11739784 direct interaction X 2 A0A087WW00 Q9NYG5 pull down 20080579 direct interaction X 2 A0A087WW00 Q9NYG5 pull down 19826003 direct interaction X 2 A0A087WW00 Q9NYG5 enzymatic study 23972993 direct interaction X 2 A0A087WW00 Q9NYG5 pull down 19475398 direct interaction X 2 P34244 Q9NYG5 enzymatic study 23078409 direct interaction X 2 P12830 Q9NYG5 pull down 12956947 direct interaction X 2 Q9P2P5 Q9NYG5 enzymatic study 24163370 direct interaction X 2 Q01094 Q9NYG5 affinity chromatography technology 25368385 physical association X 2 A0A024R5T5 Q9NYG5 two hybrid 22493164 direct interaction X 2 Q16763 Q9NYG5 pull down 22529100 direct interaction X 2 Q16763 Q9NYG5 pull down 23708001 direct interaction X 2 Q16763 Q9NYG5 pull down 23708605 direct interaction X 2 Q16763 Q9NYG5 pull down 25043029 direct interaction X 2 Q16763 Q9NYG5 pull down 25306923 direct interaction X 2 Q16763 Q9NYG5 pull down 20080579 direct interaction X 2 Q16763 Q9NYG5 pull down 23288039 direct interaction X 2 Q9NYG5 affinity chromatography technology 24302728 physical association X 2 Q9UM11 Q9NYG5 affinity chromatography technology 18662541 physical association X 2 P0CG48 Q9NYG5 x-ray crystallography 25306923 association X 2 Q9NYG5 affinity chromatography technology 20360068 physical association X 2 Q8NI77 Q9NYG5 enzymatic study 23288039 direct interaction X 2 Q9NYG5 electron tomography 25043029 physical association C 13 Q9NYG5 electron tomography 25043029 physical association C 16 Q9NYG5 electron tomography 25043029 physical association C 14 Q9NYG5 tandem affinity purification 20360068 physical association C 22 Q9NYG5 tandem affinity purification 20360068 physical association C 23 P43403 Q9NYG5 two hybrid array 21988832 physical association X 2 Q5VVX9 Q9NYG5 two hybrid array 19690564 physical association X 2 Q12834 Q9NYG5 proximity ligation assay 25241761 physical association X 2 Q6PJ69 Q9NYG5 two hybrid array 22493164 physical association X 2 Q9UMQ6 Q9NYG5 two hybrid array 21988832 physical association X 2 Q9NYG5 tandem affinity purification 20360068 association C 20 P20794 Q9NYG5 two hybrid array 21988832 physical association X 2 Q9NYG5 Q8NB16 two hybrid array 21988832 physical association X 2 Q6ZNA4 Q9NYG5 two hybrid array 22493164 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B UBE2D1 ANAPC11 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19826003,20080579,23972993 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_289557|BIOGRID_225870|BIOGRID_222946 prey|prey|prey bait|bait|bait UBE2C ANAPC11 MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0492(in vitro)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology) 11739784,16455800,17227951,17360335,18662541,19475398,19826003,20080579,20733055,21874044,21937719,22529100,22580460,23078409,23708001,23708605,23791783 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|-|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_227275|BIOGRID_225654|BIOGRID_225952|BIOGRID_251745|BIOGRID_226101|BIOGRID_225838|BIOGRID_225906|BIOGRID_225871|HPRD_32226|BIOGRID_282686|BIOGRID_281013|BIOGRID_223177|BIOGRID_222933|BIOGRID_225733|BIOGRID_225715|BIOGRID_280994|BIOGRID_225731 prey|prey|prey|prey|prey|prey|prey|prey|-|prey|prey|prey|prey|prey|prey|prey|prey bait|bait|bait|bait|bait|bait|bait|bait|-|bait|bait|bait|bait|bait|bait|bait|bait ANAPC11 FZR1 MI:0004(affinity chromatography technology) 18662541 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_251739 prey bait ANAPC11 ANAPC10 MI:0493(in vivo)|MI:0096(pull down)|MI:0492(in vitro)|MI:0493(in vivo) 10922056,11739784,16648845 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|-|- MI:0468(hprd)|(biogrid)|MI:0468(hprd)|MI:0468(hprd) HPRD_39295|BIOGRID_101794|HPRD_32227|HPRD_39911 -|bait|-|- -|prey|-|- ANAPC11 FBXO5 MI:0004(affinity chromatography technology) 16921029 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_221081 prey bait ANAPC11 ANAPC2 MI:0493(in vivo)|MI:0492(in vitro)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0492(in vitro)|MI:0096(pull down)|MI:0018(two hybrid) 10230407,10922056,11739784,12956947,24163370 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0407(direct interaction)|MI:0914(association)|-|MI:0407(direct interaction)|MI:0407(direct interaction) MI:0468(hprd)|MI:0468(hprd)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)|(biogrid) HPRD_39295|HPRD_39948|BIOGRID_101796|BIOGRID_293802|HPRD_14716|BIOGRID_101797|BIOGRID_116779 -|-|bait|bait|-|prey|bait -|-|prey|prey|-|bait|prey ANAPC11 ANAPC4 MI:0493(in vivo)|MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 10922056,12956947,16648845,21926987 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0915(physical association)|- MI:0468(hprd)|MI:0468(hprd)|(biogrid)|MI:0468(hprd) HPRD_39295|HPRD_39948|BIOGRID_143453|HPRD_39911 -|-|prey|- -|-|bait|- ANAPC11 CDC23 MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 10922056,16648845,24163370 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0914(association)|- MI:0468(hprd)|(biogrid)|MI:0468(hprd) HPRD_39295|BIOGRID_293803|HPRD_39911 -|bait|- -|prey|- ANAPC11 CAPN11 MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_286206|UniProt_118255 bait|unspecified role prey|unspecified role UBE2K ANAPC11 MI:0004(affinity chromatography technology) 18662541 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_251744 prey bait ZAP70 ANAPC11 MI:0397(two hybrid array)|MI:0004(affinity chromatography technology) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_118027|BIOGRID_286205 unspecified role|prey unspecified role|bait CDH1 ANAPC11 MI:0096(pull down) 12956947 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_85246 bait prey UBE2D2 ANAPC11 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15256223,19826003 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_225869|BIOGRID_225842 prey|prey bait|bait UBE2U ANAPC11 MI:0018(two hybrid)|MI:0397(two hybrid array) 19690564 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_123639|UniProt_102628 bait|bait prey|prey MLKL ANAPC11 MI:0397(two hybrid array)|MI:0004(affinity chromatography technology) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_118484|BIOGRID_286208 unspecified role|prey unspecified role|bait CDC27 ANAPC11 MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 10922056,12956947,14657031,16364912,16648845,24163370 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|- MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) HPRD_39295|BIOGRID_293801|BIOGRID_132835|BIOGRID_199377|BIOGRID_85245|BIOGRID_114255|HPRD_39911 -|prey|bait|bait|bait|bait|- -|bait|prey|prey|prey|prey|- RNF111 ANAPC11 MI:0397(two hybrid array)|MI:0415(enzymatic study) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_122553|BIOGRID_284065 bait|prey prey|bait CDC34 ANAPC11 MI:0004(affinity chromatography technology) 23972993 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_289558 prey bait CDC25C ANAPC11 MI:0415(enzymatic study) 12234927 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_271546 prey bait APC2 ANAPC11 MI:0096(pull down)|MI:0493(in vivo) 12956947,16648845 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_85244|HPRD_39911 bait|- prey|- TRIM65 ANAPC11 MI:0397(two hybrid array)|MI:0415(enzymatic study) 22493164 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_122554|BIOGRID_284077 bait|prey prey|bait ANAPC1 ANAPC11 MI:0493(in vivo)|MI:0096(pull down)|MI:0492(in vitro)|MI:0493(in vivo) 10922056,12956947,16648845 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|-|- MI:0468(hprd)|(biogrid)|MI:0468(hprd)|MI:0468(hprd) HPRD_39295|BIOGRID_84791|HPRD_39948|HPRD_39911 -|bait|-|- -|prey|-|- NKD2 ANAPC11 MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_286207|UniProt_120166 prey|unspecified role bait|unspecified role ANAPC11 HECW2 MI:0004(affinity chromatography technology) 24163370 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_293800 bait prey NRF1 ANAPC11 MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_295606 bait prey UBE2S ANAPC11 MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0415(enzymatic study) 22529100,23708001,23708605 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_281014|BIOGRID_280995|BIOGRID_225905 prey|prey|prey bait|bait|bait ANAPC11 ANAPC11 MI:0493(in vivo) 10922056 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_16013 - - MAK ANAPC11 MI:0004(affinity chromatography technology)|MI:0397(two hybrid array) 21988832 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_285422|UniProt_117964 prey|unspecified role bait|unspecified role CCNB1 ANAPC11 MI:0004(affinity chromatography technology)|MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20080579,22014574,23007861,23708605,24163370 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_293799|BIOGRID_281015|BIOGRID_146766|BIOGRID_247781|BIOGRID_256172 prey|prey|prey|prey|prey bait|bait|bait|bait|bait CUL5 ANAPC11 MI:0018(two hybrid) 10230407 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_116778 prey bait PTTG1 ANAPC11 MI:0096(pull down)|MI:0004(affinity chromatography technology) 19475398,20080579 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_149656|BIOGRID_146753 prey|prey bait|bait CDC20 ANAPC11 MI:0004(affinity chromatography technology) 18997788 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_116329 bait prey CDC16 ANAPC11 MI:0493(in vivo)|MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0676(tandem affinity purification)|MI:0676(tandem affinity purification)|MI:0493(in vivo) 10922056,11739784,16648845,20360068,24163370 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0914(association)|MI:0914(association)|MI:0914(association)|- MI:0468(hprd)|MI:0468(hprd)|(biogrid)|(intact)|(intact)|MI:0468(hprd) HPRD_39295|HPRD_32225|BIOGRID_293804|UniProt_170231|UniProt_106540|HPRD_39911 -|-|prey|bait|bait|- -|-|bait|prey|prey|- UBC ANAPC11 MI:0096(pull down) 19475398 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_149654 prey bait

PPI - HINT Gene A Gene B PMID Method Quality B4DL80 ANAPC11 12956947,16364912,10922056,14657031 0004,0004,0004,0004 LC UBE2C ANAPC11 23708605,23972993,21937719,22580460,26329581,22529100,18662541,27114510,25825779,11739784,21700221,23791783,25161877,23670162,23078409,21874044,25490258,17360335,19826003,23707760,27120157,23708001,25306923,25043029,20733055,25959309,22193957,25246557,16455800,22205987,23288039,17227951,20080579 0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096 LC CDC27 ANAPC11 16364912,10922056,12956947,14657031,24163370,26811472 0004,0004,0004,0004,0401,0004 LC UBE2D1 ANAPC11 20080579,25825779,19826003,19475398,26329581 0096,0096,0096,0096,0096 LC UBE2K ANAPC11 24930963,17632060,18662541 0096,0096,0096 LC UBE2D2 ANAPC11 19826003,12956947,25306923,25161877,24930963,15256223,11739784,20383333 0096,0096,0096,0096,0096,0004,0096,0096 LC CDC20 ANAPC11 25241761,18997788,25241761,26387737 0813,0004,0428,0004 LC CDC16 ANAPC11 24163370,20360068 0401,0676 LC UBE2S ANAPC11 23708605,23972993,23708001,21700221,27120157,25825779,25306923,23288039,25306918,22529100,25043029,25490258,20080579,27114510,26811472 0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096 LC ANAPC11 ANAPC4 23078409,25043029,25490258,26083744,21926987,12956947 0401,0401,0004,0401,0004,0096 LC ANAPC11 ANAPC2 12956947,24163370,11739784 0004,0401,0096 LC ANAPC11 FZR1 12956947,18662541 0096,0004 LC B4DL80 ANAPC11 12956947,16364912,10922056,14657031 0004,0004,0004,0004 LC UBE2C ANAPC11 23708605,23972993,21937719,22580460,26329581,22529100,18662541,27114510,25825779,11739784,21700221,23791783,25161877,23670162,23078409,21874044,25490258,17360335,19826003,23707760,27120157,23708001,25306923,25043029,20733055,25959309,22193957,25246557,16455800,22205987,23288039,17227951,20080579 0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096 LC CDC27 ANAPC11 16364912,10922056,12956947,14657031,24163370,26811472 0004,0004,0004,0004,0401,0004 LC UBE2D1 ANAPC11 20080579,25825779,19826003,19475398,26329581 0096,0096,0096,0096,0096 LC UBE2K ANAPC11 24930963,17632060,18662541 0096,0096,0096 LC UBE2D2 ANAPC11 19826003,12956947,25306923,25161877,24930963,15256223,11739784,20383333 0096,0096,0096,0096,0096,0004,0096,0096 LC CDC20 ANAPC11 25241761,18997788,25241761,26387737 0813,0004,0428,0004 LC CDC16 ANAPC11 24163370,20360068 0401,0676 LC UBE2S ANAPC11 23708605,23972993,23708001,21700221,27120157,25825779,25306923,23288039,25306918,22529100,25043029,25490258,20080579,27114510,26811472 0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096,0096 LC ANAPC11 ANAPC4 23078409,25043029,25490258,26083744,21926987,12956947 0401,0401,0004,0401,0004,0096 LC ANAPC11 ANAPC2 12956947,24163370,11739784 0004,0401,0096 LC ANAPC11 FZR1 12956947,18662541 0096,0004 LC PTTG1 ANAPC11 20080579,10922056,19475398,12956947,11739784 0415,0415,0415,0415,0415 LC UBB ANAPC11 27259151 0114 LC UBC ANAPC11 25306923,19475398 0114,0415 LC CCNB1 ANAPC11 20080579 0415 LC MAK ANAPC11 21988832,21988832 0397,0018 HT CDC27 ANAPC11 24163370 0401 LC ZAP70 ANAPC11 21988832,21988832 0397,0018 HT CDC16 ANAPC11 24163370 0401 LC UBE2U ANAPC11 19690564,19690564 0397,0018 HT TRIM65 ANAPC11 22493164,22493164 0018,0397 HT RNF111 ANAPC11 22493164,22493164 0018,0397 HT MLKL ANAPC11 21988832,21988832 0397,0018 HT CUL5 ANAPC11 10230407 0018 LC NKD2 ANAPC11 21988832 0018 HT ANAPC11 ANAPC11 25306923,10922056,11739784 0114,0415,0415 LC ANAPC11 CDC23 24163370 0401 LC ANAPC11 ANAPC4 23078409,25043029,26083744 0401,0401,0401 LC ANAPC11 ANAPC2 24163370,10230407 0401,0018 LC ANAPC11 CAPN11 21988832,21988832 0397,0018 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9NYG5 Q9NR09 ANAPC11 BIRC6 0.21 24302728 Q9NYG5 P14635 ANAPC11 CCNB1 0.309 23708605 Q9NYG5 P20248 ANAPC11 CCNA2 0.21 24302728 Q9NYG5 P30260 ANAPC11 CDC27 0.623 16364912,10922056,26811472,12956947,24163370 Q9NYG5 Q01094 ANAPC11 E2F1 0.21 25368385 Q9NYG5 Q12834 ANAPC11 CDC20 0.498 18997788,25241761,26387737 Q9NYG5 Q5VVX9 ANAPC11 UBE2U 0.376 19690564 Q9NYG5 Q6PJ69 ANAPC11 TRIM65 0.286 22493164 Q9NYG5 Q6ZNA4 ANAPC11 RNF111 0.286 22493164 Q9NYG5 Q93034 ANAPC11 CUL5 0.309 10230407 Q9UJX2 Q9NYG5 CDC23 ANAPC11 0.126 24163370 Q9UM13 Q9NYG5 ANAPC10 ANAPC11 0.309 11739784 Q9NYG5 P0CG48 ANAPC11 UBC 0.309 25306923 Q9NYG5 Q02930 ANAPC11 CREB5 0.236 unassigned1304 Q9NYG5 B8A4K4 ANAPC11 CYSRT1 {ECO:0000313|ENSEMBL:ENSP00000386453} 0.236 unassigned1304 Q9NYG5 Q9NYG5 ANAPC11 ANAPC11 0.554 10922056,11739784 Q9NYG5 Q8IUC1 ANAPC11 KRTAP11-1 0.236 unassigned1304 Q9NYG5 Q08117 ANAPC11 AES 0.236 unassigned1304 Q9NYG5 Q499Y1 ANAPC11 LOC151121 {ECO:0000313|EMBL:AAH93715.1} 0.236 unassigned1304 Q9NYG5 Q3LI64 ANAPC11 KRTAP6-1 0.236 unassigned1304 Q9NYG5 Q3LI66 ANAPC11 KRTAP6-2 0.236 unassigned1304 Q9NYG5 Q9BYR8 ANAPC11 KRTAP3-1 0.236 unassigned1304 Q9NYG5 Q8TDS5 ANAPC11 OXER1 0.236 unassigned1304 Q9NYG5 Q8NB16 ANAPC11 MLKL 0.286 21988832 Q9NYG5 Q9BYR6 ANAPC11 KRTAP3-3 0.236 unassigned1304 Q9NYG5 Q93062 ANAPC11 RBPMS 0.236 unassigned1304 Q9NYG5 Q96LM6 ANAPC11 TEX37 0.236 unassigned1304 Q9UMQ6 Q9NYG5 CAPN11 ANAPC11 0.286 21988832 Q9NZC7 Q9NYG5 WWOX ANAPC11 0.236 unassigned1304 Q9UJX6 Q9NYG5 ANAPC2 ANAPC11 0.748 24163370,11739784,10230407,12956947 Q9NYG5 Q8R349 ANAPC11 CDC16 0.236 20360068 Q9NYG5 Q96NS8 ANAPC11 CLUHP3 0.236 unassigned1304 Q9NYG5 Q16763 ANAPC11 UBE2S 0.998 23708605,27120157,25825779,20080579,25043029,23288039,25306918,25306923,26811472,21700221,23972993,22529100,23708001,25490258,27114510 Q9NYG5 Q52LG2 ANAPC11 KRTAP13-2 0.236 unassigned1304 Q9NYG5 Q8BGZ4 ANAPC11 CDC23 0.236 20360068 Q9NYG5 P61086 ANAPC11 UBE2K 0.671 17632060,24930963,18662541 Q9NYG5 O95997 ANAPC11 PTTG1 0.61 10922056,12956947,11739784 Q9UM11 Q9NYG5 FZR1 ANAPC11 0.472 12956947,18662541 Q9NYG5 P51668 ANAPC11 UBE2D1 0.843 19475398,26329581,19826003,25825779,20080579 Q9UJX5 Q9NYG5 ANAPC4 ANAPC11 0.748 26083744,12956947,21926987,23078409,25043029,25490258 Q9NYG5 O00762 ANAPC11 UBE2C 1 23708605,19826003,27120157,23670162,20733055,25043029,26329581,18662541,23288039,21937719,25959309,25161877,16455800,17360335,25825779,25246557,22580460,22205987,23078409,20080579,23791783,22193957,25306923,21700221,11739784,23972993,17227951,22529100,23708001,25490258,27114510,23707760 Q9NYG5 Q969F2 ANAPC11 NKD2 0.332 21988832 Q9UKT4 Q9NYG5 FBXO5 ANAPC11 0.309 16921029 Q9NYG5 P43403 ANAPC11 ZAP70 0.286 21988832 Q9NYG5 P62837 ANAPC11 UBE2D2 0.952 25306923,19826003,11739784,24930963,12956947,15256223,20383333,25161877 Q9NYG5 Q13042 ANAPC11 CDC16 0.332 20360068,24163370 Q9NYG5 P20794 ANAPC11 MAK 0.286 21988832

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 UBE2C ANAPC11 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database AURKA ANAPC11 MI:0362 inference MI:1106 pathways database PLSCR1 ANAPC11 MI:0362 inference MI:0461 interaction database BUB3 ANAPC11 MI:0362 inference MI:1106 pathways database BUB1B ANAPC11 MI:0362 inference MI:1106 pathways database UGDH ANAPC11 MI:0362 inference MI:0461 interaction database CCNB2 ANAPC11 MI:0362 inference MI:0461 interaction database HSPA4L ANAPC11 MI:0362 inference MI:0461 interaction database APC2 ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database PTTG1 ANAPC11 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database CDK1 ANAPC11 MI:0362 inference MI:1106 pathways database HSP90AB1 ANAPC11 MI:0362 inference MI:0461 interaction database TPM1 ANAPC11 MI:0362 inference MI:0461 interaction database UBB ANAPC11 MI:0362 inference MI:1106 pathways database UBC ANAPC11 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database HSPA1A ANAPC11 MI:0362 inference MI:0461 interaction database HSPA1B ANAPC11 MI:0362 inference MI:0461 interaction database HSPA8 ANAPC11 MI:0362 inference MI:0461 interaction database CDH1 ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database CCNB1 ANAPC11 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database HSPA6 ANAPC11 MI:0362 inference MI:0461 interaction database CCNA2 ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database MAK ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database FBLN1 ANAPC11 MI:0362 inference MI:0461 interaction database CDK2 ANAPC11 MI:0362 inference MI:1106 pathways database CDC27 ANAPC11 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database CDC25A ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database CKS2 ANAPC11 MI:0362 inference MI:0461 interaction database HSPA1L ANAPC11 MI:0362 inference MI:0461 interaction database HSPA4 ANAPC11 MI:0362 inference MI:0461 interaction database HSPA9 ANAPC11 MI:0362 inference MI:0461 interaction database ZAP70 ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database CDC34 ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database PSMD7 ANAPC11 MI:0362 inference MI:0461 interaction database UBE2D1 ANAPC11 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database NEK2 ANAPC11 MI:0362 inference MI:1106 pathways database UBE2E1 ANAPC11 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database PLK1 ANAPC11 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database HSPA2 ANAPC11 MI:0362 inference MI:0461 interaction database ANAPC15 ANAPC11 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database CKS1B ANAPC11 MI:0362 inference MI:0461 interaction database UBE2K ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database CNBP ANAPC11 MI:0362 inference MI:0461 interaction database RPL23A ANAPC11 MI:0362 inference MI:0461 interaction database UBE2D2 ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database RPS27A ANAPC11 MI:0362 inference MI:1106 pathways database UBA52 ANAPC11 MI:0362 inference MI:1106 pathways database E2F1 ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database CDC20 ANAPC11 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database CDC16 ANAPC11 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database MAD2L1 ANAPC11 MI:0362 inference MI:1106 pathways database SKP2 ANAPC11 MI:0362 inference MI:1106 pathways database KCTD2 ANAPC11 MI:0362 inference MI:0461 interaction database UBE2S ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database FBXO43 ANAPC11 MI:0362 inference MI:0461 interaction database UBE2U ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database TRIM65 ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database RNF111 ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database FTMT ANAPC11 MI:0362 inference MI:0461 interaction database KCTD17 ANAPC11 MI:0362 inference MI:0461 interaction database MLKL ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database CDC26 ANAPC11 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database KIF18A ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database ZCCHC13 ANAPC11 MI:0362 inference MI:0461 interaction database HSPH1 ANAPC11 MI:0362 inference MI:0461 interaction database COPS5 ANAPC11 MI:0362 inference MI:0461 interaction database CUL5 ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database NKD2 ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database UBE2E3 ANAPC11 MI:0362 inference MI:0461 interaction database ISOC2 ANAPC11 MI:0362 inference MI:0461 interaction database ANAPC16 ANAPC11 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database AURKB ANAPC11 MI:0362 inference MI:1106 pathways database EHMT2 ANAPC11 MI:0362 inference MI:1106 pathways database UBE2E2 ANAPC11 MI:0362 inference MI:0461 interaction database WDFY2 ANAPC11 MI:0362 inference MI:0461 interaction database SRPK1 ANAPC11 MI:0362 inference MI:0461 interaction database ANAPC13 ANAPC11 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database FTHL17 ANAPC11 MI:0362 inference MI:0461 interaction database ANAPC1 ANAPC11 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PLK3 ANAPC11 MI:0362 inference MI:0461 interaction database EHMT1 ANAPC11 MI:0362 inference MI:1106 pathways database BIRC6 ANAPC11 MI:0045 experimental interaction detection MI:0461 interaction database KCTD5 ANAPC11 MI:0362 inference MI:0461 interaction database ANAPC11 PLK2 MI:0362 inference MI:0461 interaction database ANAPC11 HECW2 MI:0045 experimental interaction detection MI:0461 interaction database ANAPC11 CDC23 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC11 ANAPC7 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database ANAPC11 ANAPC5 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database ANAPC11 ANAPC4 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC11 ANAPC2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC11 FBXO5 MI:0045 experimental interaction detection MI:0461 interaction database ANAPC11 FZR1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC11 ANAPC10 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ANAPC11 CAPN11 MI:0045 experimental interaction detection MI:0461 interaction database ANAPC11 SRPK3 MI:0362 inference MI:0461 interaction database ANAPC11 UBE2D4 MI:0362 inference MI:0461 interaction database