DNA & RNA Element - UTRdb Gene Name Type ASPicDB UTRaspic Refseq ID Genome FBXO15 3'UTR 5e34f3fab3 BA039757 NM_001142958 chr18:69891585-69954079:- FBXO15 3'UTR dd92e8b1a5 BA039758 NM_001142958 chr18:69891568-69954079:- FBXO15 3'UTR 198347a6be NM_001142958 chr18:69941153-69944317:- FBXO15 3'UTR 40eab1ddba NM_001142958 chr18:69891568-69941645:- FBXO15 5'UTR 5e34f3fab3 CA061662 NM_001142958 chr18:69891677-69965929:- FBXO15 5'UTR dd92e8b1a5 CA061663 NM_001142958 chr18:69891677-69966080:- FBXO15 5'UTR ca867964ed NM_001142958 chr18:69944191-69966000:-

DNA & RNA Element - AREsite Gene Name Motif CDS Area ARE Area Evidence FBXO15; FBX15 ATTTA 404-1708 1734-1738

DNA & RNA Element - CircNet Circ ID GITPosition Express Symbol Entrez Category Strand Refered Name hsa-circ-FBXO15.1 NM_152676Tchr18:71793209-71807547 expressed FBXO15 201456 protein-coding - hsa_circ_0108873 hsa-circ-FBXO15.4 NM_001142958Tchr18:71749161-71803101 expressed FBXO15 201456 protein-coding - hsa_circ_0108872

DNA & RNA Element - microRNA Mirbase Acc miRNA Name Gene ID Gene Symbol miRNA Alignment Alignment Gene Alignment miRNA Start miRNA End Gene Start Gene End Genome Coordinates Conservation Align Score Seed Cat Energy mirSVR Score MIMAT0004494 hsa-miR-21* 201456 FBXO15 ugUCGGGUAGCUGACCACAAc :||:: : :||||||| cuGGCUUUGUUCUUGGUGUUg 2 20 46 66 [hg19:18:71740630-71740650:-] 0.5598 143 7 -17.92 -0.7362 MIMAT0004615 hsa-miR-195* 201456 FBXO15 ccUCGUCGUGUCGGUU-AUAACc ||:|| :::|| || ||||| -cAGUAG-GUGGCAAAUUAUUGu 2 21 1 21 [hg19:18:71740675-71740695:-] 0.5569 126 0 -11.43 -0.5344 MIMAT0002879 hsa-miR-507 201456 FBXO15 aagugagGUUUUCCA-CGUUUu ||: |||| ||||| -------CAGUAGGUGGCAAAu 2 15 1 15 [hg19:18:71740681-71740695:-] 0.5569 122 0 -11.10 -0.5428 MIMAT0003240 hsa-miR-575 201456 FBXO15 cgAGGACAGGUUGACCGAg |: | |:::||||||| guUUAUUUUUGACUGGCUu 2 18 34 52 [hg19:18:71740644-71740662:-] 0.5598 153 7 -14.87 -0.9752 MIMAT0003271 hsa-miR-603 201456 FBXO15 cgUUUUCAUUA-ACG--UCAC-ACAc |||: ||| ||| |||| ||| auAAAGCAAAUCUGCAGAGUGCUGUg 2 21 76 101 [hg19:18:71740595-71740620:-] 0.5873 122 0 -14.40 -0.9833 MIMAT0005893 hsa-miR-1305 201456 FBXO15 agAGAGGGUAAUCUCAACUUUu |:| :: ||:| ||||||| gcUUUGUUCUUGGUGUUGAAAa 2 21 49 70 [hg19:18:71740626-71740647:-] 0.5690 160 7 -17.15 -1.0630 MIMAT0005907 hsa-miR-1256 201456 FBXO15 ucgaUCACUCUUCA-GUUACGGa || | | || ||||||| cugcAGAGUGCUGUGCAAUGCC- 2 19 87 108 [hg19:18:71740588-71740609:-] 0.5873 149 7 -16.67 -0.5041 MIMAT0015378 hsa-miR-3065-3p 201456 FBXO15 gaggUUG-UUAUAGGAC-CACGACu |:| ||| | | | |||||| auaaAGCAAAUCUGCAGAGUGCUGu 2 20 76 100 [hg19:18:71740596-71740620:-] 0.5873 122 6 -15.75 -0.4122 MIMAT0016902 hsa-miR-4272 201456 FBXO15 uguuagugauCAACUUac |||||| uguucuugguGUUGAAaa 3 9 53 70 [hg19:18:71740626-71740643:-] 0.6088 120 0 -4.79 -0.1217 MIMAT0000081 hsa-miR-25 201456 FBXO15 agucUGGCUCUGUUCACGUUAc :| ||| ||||||| aucuGCAGAGUGCUGUGCAAUg 2 19 85 106 [hg19:18:71740590-71740611:-] 0.5873 146 7 -19.84 -0.1951 MIMAT0000090 hsa-miR-32 201456 FBXO15 acGUUGAAUCAUUACACGUUAu | :| |||: |||||||| auCUGCAGAGUGCUGUGCAAUg 2 21 85 106 [hg19:18:71740590-71740611:-] 0.5873 160 7 -20.05 -0.1970 MIMAT0000092 hsa-miR-92a 201456 FBXO15 ugucCGGCCCUGUUCACGUUAu || | | ||||||| aucuGCAGAGUGCUGUGCAAUg 2 19 85 106 [hg19:18:71740590-71740611:-] 0.5873 142 7 -13.83 -0.1988 MIMAT0000707 hsa-miR-363 201456 FBXO15 auGUCUACCUAUGGCACGUUAa | | | :|:|:||||||| auCUGCAGAGUGCUGUGCAAUg 2 21 85 106 [hg19:18:71740590-71740611:-] 0.5873 156 7 -20.69 -0.2007 MIMAT0000719 hsa-miR-367 201456 FBXO15 aguggUAACGAUUUCACGUUAa | |||| ||||||| ugcagAGUGCU---GUGCAAUg 2 18 88 106 [hg19:18:71740590-71740608:-] 0.5873 145 7 -13.07 -0.1798 MIMAT0003218 hsa-miR-92b 201456 FBXO15 ccucCGGCCCUGCUCACGUUAu || | | ||||||| aucuGCAGAGUGCUGUGCAAUg 2 19 85 106 [hg19:18:71740590-71740611:-] 0.5873 142 7 -14.28 -0.1988 MIMAT0003339 hsa-miR-421 201456 FBXO15 cgCGGGUUAAUUACAGACAACUa ||:: :|| || |||||| ugGCUUUGUUCUUG-GUGUUGAa 2 22 47 68 [hg19:18:71740628-71740649:-] 0.5598 123 6 -11.63 -0.1163

DNA & RNA Element - TRANSFAC Accession AS Description Species Entrez Pubmed Binding Info G021310 FBXO15 Homo sapiens 201456

DNA & RNA Element - RepTar Gene Name miRNA Begin End Profile FBXO15 hsa-miR-575 beg:38 end:53 pic:3' CGAGGACAGGTTGACCGAG 5'& |. |||||||. &5' -------TTTGACTGGCTT 3' FBXO15 hsa-miR-1305 beg:48 end:71 pic:3' AGAGAGGGTAATCTCAACTTTT 5'& ||.| . ||.| |||||||| &5' -CTTTGTTCTTGGTGTTGAAAA 3' FBXO15 hsa-miR-196astar beg:6 end:26 pic:3' GAGTCCGTCAAAGAACAACGGC 5'& |||| ||||||.. &5' ----GGCAAATTATTGTTGTT- 3' FBXO15 hsa-miR-29a beg:52 end:67 pic:3' ATTGGCTAAAGTCTACCACGAT 5'& ||| |||||.|. &5' --------TTCT--TGGTGTTG 3' FBXO15 hsa-miR-3065-3p beg:45 end:68 pic:3' GAGGTTGTTAT-AGGACCACGACT 5'& | .| |. ||.|||||.||| &5' --CTGGCTTTGTTCTTGGTGTTGA 3' FBXO15 hsa-miR-335 beg:44 end:62 pic:3' TGTAAAAAGCAATAACGAGAACT 5'& .| |||.|||||. &5' --------TGGCTTTGTTCTTGG 3' FBXO15 hsa-miR-549 beg:6 end:27 pic:3' TCTCGAGTAGGTATCAACAGT 5'& .|| ||. |||||.| &5' --GGCAAATTATT-GTTGTTA 3' FBXO15 hsa-miR-549 beg:18 end:37 pic:3' TCTCGAGTAGGT-ATCAACAGT 5'& | |. |||||||. &5' -----TTGTTATTTAGTTGTT- 3' FBXO15 hsa-miR-9star beg:35 end:56 pic:3' TGAAAGCCAATAGATCGAAATA 5'& |.|||.| ||.|||||.| &5' ATTTTTGA----CTGGCTTTGT 3' FBXO15 kshv-miR-K12-1star beg:46 end:67 pic:3' CCAACGTCCTTTGT-CCACGACG 5'& || ||||.|| &5' ----GCTTTGTTCTTGGTGTTG- 3'

DNA & RNA Element - miRcode Gene Name Type microRNA Seed Position Seed Type Total Cons% Tr Region FBXO15 High_conserved miR-132/212/212-3p chr18:71796746 7-mer-A1 13 CDS FBXO15 High_conserved miR-133abc chr18:71797662 7-mer-A1 27 CDS FBXO15 High_conserved miR-9/9ab chr18:71797660 8-mer 42 CDS FBXO15 High_conserved miR-139-5p chr18:71814894 7-mer-m8 7 5pUTR FBXO15 High_conserved miR-150/5127 chr18:71807471 7-mer-A1 11 CDS, 5pUTR FBXO15 High_conserved miR-183 chr18:71807495 7-mer-m8 9 CDS, 5pUTR FBXO15 High_conserved let-7/98/4458/4500 chr18:71749217 7-mer-m8 40 CDS FBXO15 High_conserved miR-196abc chr18:71790637 7-mer-A1 13 CDS FBXO15 High_conserved miR-214/761/3619-5p chr18:71807454 7-mer-m8 7 CDS, 5pUTR FBXO15 High_conserved miR-23abc/23b-3p chr18:71749262 7-mer-A1 33 CDS FBXO15 High_conserved miR-25/32/92abc/363/363-3p/367 chr18:71740590 7-mer-m8 0 3pUTR FBXO15 High_conserved miR-129-5p/129ab-5p chr18:71740724 7-mer-m8 27 CDS FBXO15 High_conserved miR-129-5p/129ab-5p chr18:71796729 8-mer 36 CDS FBXO15 Medium_conserved miR-544/544ab/544-3p chr18:71807545 8-mer 2 CDS FBXO15 Medium_conserved miR-590-3p chr18:71740623 7-mer-A1 0 3pUTR FBXO15 Medium_conserved miR-615-3p chr18:71791730 7-mer-m8 36 CDS FBXO15 Medium_conserved miR-615-3p chr18:71814976 7-mer-m8 9 CDS, 5pUTR FBXO15 Medium_conserved miR-758 chr18:71797744 7-mer-A1 16 CDS FBXO15 Medium_conserved miR-873 chr18:71807441 7-mer-m8 9 CDS, 5pUTR FBXO15 Medium_conserved miR-186 chr18:71793318 8-mer 40 CDS FBXO15 Medium_conserved miR-197 chr18:71815033 8-mer 9 5pUTR FBXO15 Medium_conserved miR-296-3p chr18:71797688 7-mer-m8 24 CDS FBXO15 Medium_conserved miR-299/299-3p/3563-3p chr18:71790723 7-mer-A1 13 CDS FBXO15 Medium_conserved miR-342-3p chr18:71803026 7-mer-m8 18 CDS FBXO15 Medium_conserved miR-370 chr18:71814948 7-mer-m8 9 CDS, 5pUTR FBXO15 Medium_conserved miR-376abd/376b-3p chr18:71790736 7-mer-A1 16 CDS FBXO15 Medium_conserved miR-376abd/376b-3p chr18:71797801 7-mer-m8 20 CDS FBXO15 Medium_conserved miR-377 chr18:71803027 7-mer-m8 60 CDS FBXO15 Medium_conserved miR-379/1193-5p/3529 chr18:71793278 7-mer-A1 16 CDS FBXO15 Medium_conserved miR-410/344de/344b-1-3p chr18:71796742 7-mer-m8 13 CDS FBXO15 Medium_conserved miR-421 chr18:71740628 7-mer-A1 11 3pUTR FBXO15 Medium_conserved miR-125a-3p/1554 chr18:71797852 7-mer-m8 2 CDS FBXO15 Medium_conserved miR-450a/451a chr18:71740726 8-mer 9 CDS FBXO15 Medium_conserved miR-494 chr18:71740905 7-mer-A1 47 CDS FBXO15 Medium_conserved miR-495/1192 chr18:71791782 7-mer-A1 33 CDS

DNA & RNA Element - RAID2 Gene Name RAID ID Interactor 1 Category 1 ID 1 Interactor 2 Category 2 ID 2 Methods Score FBXO15 RAID00113747 hsa-miR-92b-3p miRNA MIMAT0003218 FBXO15 mRNA 201456 Prediction 0.1828 FBXO15 RAID00630223 hsa-miR-25-3p miRNA MIMAT0000081 FBXO15 mRNA 201456 Prediction 0.1828 FBXO15 RAID02186226 hsa-miR-32-5p miRNA MIMAT0000090 FBXO15 mRNA 201456 Prediction 0.1828 FBXO15 RAID03085981 hsa-miR-92a-3p miRNA MIMAT0000092 FBXO15 mRNA 201456 Prediction 0.1828 FBXO15 RAID03390221 hsa-miR-363-3p miRNA MIMAT0000707 FBXO15 mRNA 201456 Prediction 0.1828 FBXO15 RAID03557557 hsa-miR-367-3p miRNA MIMAT0000719 FBXO15 mRNA 201456 Prediction 0.1828 FBXO15 RAID04026491 hsa-miR-421 miRNA MIMAT0003339 FBXO15 mRNA 201456 Prediction 0.1828