iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

PPI - IID
Symbol 1	Symbol 2	PMID	DBs	Evidence Type	Adipose Tissue	Adrenal Gland	Amygdala	Bone	Bone Marrow	Brain	Dorsal Root Ganglia	Eye	Heart	Hindgut	Hypothalamus	Kidney	Liver	Lung	Lymph Nodes	Mammary Gland	Midgut	Neurons	Ovary	Pancreas	Pituitary Gland	Placenta	Prostate	Salivary Gland	Skeletal Muscle	Small Intestine	Spleen	Stomach	Testes	Uterus
NF1	NOSIP	26344197	biogrid	exp	GP	GP	G	G	GP	GP	G		GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	GP	GP	GP	GP	G
TNNC2	NOSIP	26186194	biogrid	exp	G	GP	G	G	GP	G			P	GP	G		P	GP			G	G		G	G		G	G	GP	G	P		GP
BCAR3	NOSIP	17353931	intact	exp	GP	GP	G		P	GP	G		GP	GP	G	GP	GP	GP	GP	G	GP	GP	G	P	G	GP	GP	GP	GP	GP	G	GP	GP	G
HECW2	NOSIP	24163370	biogrid	exp	GP	GP	G	G	GP	GP	G		GP	GP	G	GP	G	GP	G	G	P	GP	P	GP	G	GP	GP	GP	GP	GP	G	GP	GP
HMCES	NOSIP	26344197	biogrid	exp	GP	GP	G	G	GP	GP	G		G	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	G	GP	GP	GP	GP	G
JUN	NOSIP	25609649	intact	exp	GP	GP	G	G	G	GP	G		G	GP	G	GP	G	GP	G	G	GP	GP	G	G	G	GP	G	GP	G	GP	G	GP	G	G
NOS1	NOSIP	15548660	hprd	exp		G	G	G	G	GP	G		G		G	G	G	G	G			GP	G	G	G	G	G	G	G	G			G	G
POLL	NOSIP	26186194	biogrid	exp																													G
ATR	NOSIP	26344197	biogrid	exp	G	GP	G	G	G	GP	G		GP	GP	G	GP	GP	GP	G	G	G	GP	G	GP	G	GP	G	G	G	G	G	G	GP	G
NOSIP	NEU2	26186194	biogrid	exp		P								P		P		P			P									P		P	P
KPNA1	NOSIP	16135813	biogrid	exp	GP	GP	G	G	G	GP	G		GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	G	GP	G	GP	GP	GP	G	GP	GP	G
WWOX	NOSIP	24550385	biogrid	exp	GP	GP	G	G	GP	GP	G		GP	GP	G	GP	GP	GP	GP	G	GP	GP	G	GP	G	GP	GP	GP	GP	GP	GP	GP	GP	G
DDX42	NOSIP	22939629	biogrid	exp	GP	GP	G	G	GP	GP	G		GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	GP	GP	GP	GP	G
DDX17	NOSIP	26344197	biogrid	exp	GP	GP	G	G	GP	GP	G		GP	G	G	GP	G	GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	GP	GP	GP	GP	G
EPOR	NOSIP	12746455	biogrid	exp	G	G	G	G	G	G	G		G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
FAM212B	NOSIP	26186194	biogrid	exp	G	P	G		P	GP	G		GP	P		GP	P	P	P	G	GP	GP	P	P	G	P	GP	P	G	GP	P	P	P
SLC25A21	NOSIP	26186194	biogrid	exp	P	P			P	P				P		P	P	P			P	P		P		P	P		P	P	P	P
CUL3	NOSIP	21145461	biogrid	exp	GP	GP	G	G	GP	GP	G		GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	GP	GP	GP	GP	G
OTUB1	NOSIP	unassigned1260	intact	exp	GP	GP	G	G	GP	GP	G		GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	GP	GP	GP	GP	G
NOS3	NOSIP	16135813,11149895, 21836163	hprd,biogrid	exp, pred									G	P		P	G									GP					G
LMLN	NOSIP			ortho	GP	GP	G	G	G	GP	G		GP	G	G	GP	GP	GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	GP	GP	GP	GP	G
FOXP3	NOSIP			ortho		G					G		G					P	P							G		G	G		P		P
SLC35B4	NOSIP	21836163		pred	GP	GP	G	G	GP	GP	G		GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	G	GP	GP	GP	GP	G
FUT8	NOSIP	21836163		pred	G	GP	G	G	GP	GP	G		G	GP	G	GP	P	GP	GP	G	GP	GP	G	GP	G	GP	GP	GP	P	GP	GP	GP	GP	G
SLC35A2	NOSIP	21836163		pred	GP	GP	G	G	GP	GP	G		GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	GP	GP	GP	GP	G
EDF1	NOSIP	21836163		pred	GP	GP	G	G	GP	GP	G		GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	G	GP	GP	GP	GP	G
GOLIM4	NOSIP	21836163		pred	GP	GP	G	G	GP	GP	G		GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	GP	GP	GP	GP	G
ATP2C1	NOSIP	21836163		pred	GP	GP	G	G	GP	GP	G		GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	G	GP	GP	GP	GP	GP	GP	GP	GP	G
CAV1	NOSIP	21836163		pred	GP	G	G	G	G	GP	G		GP	GP	G	GP	GP	GP	G	G	G	GP	GP	G	G	GP	GP	G	G	G	G	G	G	G

PPI - iRefIndex
UniProt A	UniProt B	Method	PMID	Interaction Type	Edge type	Num Participants
Q9P2P5	Q9Y314	affinity chromatography technology	24163370	physical association	X	2
P61956-2	Q9Y314	affinity chromatography technology	19471022	physical association	X	2
Q9Y314	A0A024R475	affinity chromatography technology	21145461	physical association	X	2
P52294	Q9Y314	pull down	16135813	direct interaction	X	2
Q86XP3	Q9Y314	biochemical	22939629	colocalization	X	2
	Q9Y314	affinity chromatography technology	15548660	physical association	X	2
	Q9Y314	affinity chromatography technology	15548660	physical association	X	2
P19235	Q9Y314	affinity chromatography technology	12746455	physical association	X	2
Q9Y314	Q9NZC7-5	affinity chromatography technology	24550385	physical association	X	2
A0A0A0MTA6	Q9Y314	affinity chromatography technology	16135813	physical association	X	2
A0A0A0MTA6	Q9Y314	two hybrid	11149895	direct interaction	X	2
A0A0A0MTA6	Q9Y314	affinity chromatography technology	11149895	physical association	X	2
A0A0A0MTA6	Q9Y314	pull down	11149895	direct interaction	X	2
A0A0A0MTA6	Q9Y314	affinity chromatography technology	11149895	physical association	X	2
A0A0A0MTA6	Q9Y314	pull down	11149895	direct interaction	X	2
P0CG48	Q9Y314	affinity chromatography technology	22505724	physical association	X	2
P0CG48	Q9Y314	affinity chromatography technology	23000965	physical association	X	2
P0CG48	Q9Y314	affinity chromatography technology	24816145	physical association	X	2
P0CG48	Q9Y314	affinity chromatography technology	21139048	physical association	X	2
P0CG48	Q9Y314	affinity chromatography technology	21890473	physical association	X	2
P0CG48	Q9Y314	affinity chromatography technology	21906983	physical association	X	2
	Q9Y314	in vivo	11149895	-	X	2
	Q9Y314	in vitro	11149895	-	X	2
	Q9Y314	two hybrid	11149895	-	X	2
	Q9Y314	in vivo	11149895	-	X	2
	Q9Y314	two hybrid	11149895	-	X	2
	Q9Y314	in vitro	11149895	-	X	2
B3VK56	Q9Y314	in vivo	15548660	-	X	2
B3VK56	Q9Y314	in vivo	15548660	-	X	2
O75815	Q9Y314	anti bait coimmunoprecipitation	17353931	physical association	X	2

PPI - HINT
Gene A	Gene B	PMID	Method	Quality
BCAR3	NOSIP	17353931	0006	HT
TNNC2	NOSIP	26186194	0004	HT
JUN	NOSIP	25609649	0006	HT
NF1	NOSIP	26344197	0401	HT
NOS3	NOSIP	11149895,11149895,16135813,11149895	0018,0004,0004,0096	LC
MCM2	NOSIP	25963833	0004	HT
ATR	NOSIP	26344197	0401	HT
CUL3	NOSIP	21145461	0004	HT
DDX42	NOSIP	22939629	0401	HT
DDX17	NOSIP	26344197	0401	HT
HMCES	NOSIP	26344197	0401	HT
SLC25A21	NOSIP	26186194	0004	HT
FAM212B	NOSIP	26186194	0004	HT
POLL	NOSIP	26186194	0004	HT
NOSIP	NEU2	26186194	0004	HT
BCAR3	NOSIP	17353931	0006	HT
TNNC2	NOSIP	26186194	0004	HT
JUN	NOSIP	25609649	0006	HT
NF1	NOSIP	26344197	0401	HT
MCM2	NOSIP	25963833	0004	HT
ATR	NOSIP	26344197	0401	HT
CUL3	NOSIP	21145461	0004	HT
DDX42	NOSIP	22939629	0401	HT
DDX17	NOSIP	26344197	0401	HT
HMCES	NOSIP	26344197	0401	HT
SLC25A21	NOSIP	26186194	0004	HT
FAM212B	NOSIP	26186194	0004	HT
POLL	NOSIP	26186194	0004	HT
NOSIP	NEU2	26186194	0004	HT
NOS3	NOSIP	11149895,11149895,16135813,11149895	0018,0004,0004,0096	LC
NF1	NOSIP	26344197	0401	LC
NOS3	NOSIP	11149895,11149895,11149895	0018,0004,0096	LC
PPP2CA	NOSIP	25546391,25546391,25546391	0004,0096,0415	LC
ATR	NOSIP	26344197	0401	LC
DDX42	NOSIP	22939629	0401	LC
DDX17	NOSIP	26344197	0401	LC
HMCES	NOSIP	26344197	0401	LC

PPI - Mentha
Protein A	Protein B	Gene A	Gene B	Score	PMID
Q9Y314	Q61097	NOSIP	KSR1	0.126	26549023
Q9Y314	Q9NTI7	NOSIP	FAM212B	0.126	26186194
Q9Y314	Q9NZC7	NOSIP	WWOX	0.126	24550385
Q9Y3R4	Q9Y314	NEU2	NOSIP	0.126	26186194
Q9Y314	Q96FZ2	NOSIP	HMCES	0.081	26344197
Q9Y314	P19235	NOSIP	EPOR	0.21	12746455
Q9Y314	P61077	NOSIP	UBE2D3	0.309	25546391
Q9Y314	P02585	NOSIP	TNNC2	0.126	26186194
Q9Y314	P62714	NOSIP	PPP2CB	0.21	25546391
Q9Y314	O75815	NOSIP	BCAR3	0.126	17353931
Q9Y314	P05412	NOSIP	JUN	0.126	25609649
Q9Y314	P30153	NOSIP	PPP2R1A	0.454	25546391
Q9Y314	P63151	NOSIP	PPP2R2A	0.454	25546391
Q9Y314	Q86VK4	NOSIP	ZNF410	0.236	unassigned1304
Q9Y314	Q96FW1	NOSIP	OTUB1	0.236	26752685
Q9Y314	P29474	NOSIP	NOS3	0.837	11149895,16135813
Q9Y314	P67775	NOSIP	PPP2CA	0.623	25546391
Q9Y314	Q92841	NOSIP	DDX17	0.081	26344197
Q9Y314	P29476	NOSIP	NOS1	0.376	15548660
Q9Y314	Q9BQT8	NOSIP	SLC25A21	0.126	26186194
Q9Y314	Q9UGP5	NOSIP	POLL	0.126	26186194
Q9Y314	Q9P2P5	NOSIP	HECW2	0.126	24163370
Q9Y314	Q13535	NOSIP	ATR	0.081	26344197
Q9Y314	Q13618	NOSIP	CUL3	0.126	21145461
Q9Y314	P49736	NOSIP	MCM2	0.126	25963833
Q9Y314	P52294	NOSIP	KPNA1	0.309	16135813
Q9Y314	P21359	NOSIP	NF1	0.081	26344197

PPI - InWeb_IM
Gene A	Gene B	MI 1	Interaction 1	MI 2	Interaction 2
BCAR3	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
TNNC2	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
JUN	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
UBC	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
EPOR	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
TAF1	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
NOS3	NOSIP	MI:0045	experimental interaction detection	MI:0461,MI:1106	interaction database,pathways database
NOS1	NOSIP	MI:0362	inference	MI:0461	interaction database
PPP2R1A	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
HNF4A	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
MCM2	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
KPNA1	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
UBE2D3	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
SUMO2	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
PPP2CB	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
PPP2R2A	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
PPP2CA	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
CUL3	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
KSR1	NOSIP	MI:0362	inference	MI:0461	interaction database
RFWD2	NOSIP	MI:0362	inference	MI:0461	interaction database
OTUB1	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
LMLN	NOSIP	MI:0362	inference	MI:0461	interaction database
SLC25A21	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
FOXP3	NOSIP	MI:0362	inference	MI:0461	interaction database
FAM212B	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
WWOX	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
HECW2	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
POLL	NOSIP	MI:0045	experimental interaction detection	MI:0461	interaction database
NOSIP	NEU2	MI:0045	experimental interaction detection	MI:0461	interaction database