PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus PRMT6 MTF2 23455924 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G JAK3 MTF2 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PIK3R3 MTF2 25814554 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CREB1 MTF2 20211142 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SUV39H2 MTF2 23455924 biogrid,intact exp G G G G G G G G G G G G G G PRKD2 MTF2 15231748 biogrid,i2d,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TMED9 MTF2 21988832 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KIF2A MTF2 26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SUV39H1 MTF2 23455924 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RBBP7 MTF2 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SMAD3 MTF2 15231748 hprd,biogrid,i2d,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G VOPP1 MTF2 16169070 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GSK3B MTF2 21900206 biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ELAVL1 MTF2 19322201 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GPRASP1 MTF2 16169070 hprd,i2d exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM1A MTF2 23455924 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G EZH2 MTF2 24457600,20123894, 25402006 innatedb,biogrid exp, ortho, pred G G G G G G G G G G G G JARID2 MTF2 20123894, 25402006 biogrid exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G EED MTF2 26496610, 25402006 biogrid,intact exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SUZ12 MTF2 24457600,20123894, 25402006 innatedb,biogrid exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ICE1 MTF2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C17orf96 MTF2 ortho G G G G G NAP1L2 MTF2 ortho G G G G G G G G G G G G G G G G G G G G G G G RBBP4 MTF2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G EZH1 MTF2 25402006 ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM35 MTF2 25402006 ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G ELL MTF2 25402006 ortho, pred G G G G G G G G G G G G STK38 MTF2 25402006 ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RIMBP3B MTF2 23023127 pred FXR2 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KIF1A MTF2 23023127 pred G G G G G G G G G G G G G G G G RUSC1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KIF13B MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CLIP4 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G GRAP2 MTF2 23023127 pred MAGI3 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIM46 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SASH3 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CLIP1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RASA1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CLIP2 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G CLIP3 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G SH3RF2 MTF2 23023127 pred G G SH3GL2 MTF2 23023127 pred G G G G G G G G G DNTT MTF2 25402006 pred G G G G G G G G G G G G G G G G G G G ABL2 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SNRPF MTF2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G KDM4C MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PHF20 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TRIO MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TP53BP1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SMN1, SMN2 MTF2 23023127 pred CNKSR2 MTF2 23023127 pred G G G G G G G G G G G G G G STAC2 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G ARID4B MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RIMBP3C MTF2 23023127 pred SH3KBP1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G STK31 MTF2 23023127 pred G RIMBP2 MTF2 23023127 pred G G G G G G G G G G G G G KMT2A MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RBBP6 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSIP1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PYGO1 MTF2 23023127 pred G G G G G BZRAP1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G RIMBP3 MTF2 23023127 pred CBX6 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NGEF MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G HDGF MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HDAC1 MTF2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HDAC2 MTF2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLEKHA1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RNF17 MTF2 23023127 pred G G G G G G G G G G G G G G SH3PXD2A MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SRGAP2 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G SMNDC1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MED13L MTF2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BAIAP2L2 MTF2 23023127 pred G G G G G G PHF3 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GRB2 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ZNF91 MTF2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SRGAP3 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G TDRD3 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G ARID4A MTF2 23023127 pred G G G G G G G G G G G G G G G G G G TDRD1 MTF2 23023127 pred G ARHGEF7 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NCK1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MTF2 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RERE MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DCTN1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TDRD5 MTF2 23023127 pred G HDGFL1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PKN2 MTF2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SNRPN MTF2 23023127 pred G G G G SETDB1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BPTF MTF2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BIN1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G AHI1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PHF20L1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MBD5 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MAPK8IP2 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WHSC1 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G EPS8L3 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G DNMT3B MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G CEP350 MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TDRKH MTF2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G MIB2 MTF2 23023127 pred G G G G G G G G G G G G G G G G BSN MTF2 23023127 pred G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9BZL6 Q9Y483 two hybrid 15231748 physical association X 2 Q9Y483 Q9BVK6 two hybrid array 21988832 physical association X 2 Q9Y483 Q9H5I1 two hybrid 23455924 physical association X 2 P49841 Q9Y483 two hybrid 21900206 physical association X 2 Q9Y483 O60341 two hybrid 23455924 physical association X 2 Q96LA8 Q9Y483 two hybrid 23455924 physical association X 2 A0A024R5Z3 Q9Y483 two hybrid 15231748 physical association X 2 Q96AW1 Q9Y483 two hybrid pooling approach 16169070 physical association X 2 O43463 Q9Y483 two hybrid 23455924 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9Y483 O43463 MTF2 SUV39H1 0.332 23455924 Q9Y483 Q8N655 MTF2 C10ORF12 0.236 27705803 Q9Y483 P16220 MTF2 CREB1 0.183 20211142 Q9Y483 O60341 MTF2 KDM1A 0.332 23455924 Q9Y483 Q9H5I1 MTF2 SUV39H2 0.332 23455924 Q9Y483 O75530 MTF2 EED 0.416 26496610,27705803 Q9Y483 Q96EA4 MTF2 SPDL1 0.126 27705803 Q9Y483 Q16576 MTF2 RBBP7 0.332 27705803,26186194 Q9Y483 Q9BVK6 MTF2 TMED9 0.286 21988832 Q9Y483 Q15910 MTF2 EZH2 0.583 20123894,27705803,24457600 Q9Y483 Q96LA8 MTF2 PRMT6 0.332 23455924 Q9Y483 Q92569 MTF2 PIK3R3 0.286 25814554 Q9Y483 Q9BZL6 MTF2 PRKD2 0.332 15231748 Q9Y483 Q9DCX1 MTF2 MAD2L1BP 0.236 26496610 Q9Y483 O00139 MTF2 KIF2A 0.236 26496610 Q9Y483 P49841 MTF2 GSK3B 0.332 21900206 Q9Y483 P52333 MTF2 JAK3 0.236 26496610 Q9Y483 Q92800 MTF2 EZH1 0.236 27705803 Q9Y483 Q92833 MTF2 JARID2 0.309 20123894,27705803 Q9Y483 Q96AW1 MTF2 VOPP1 0.126 16169070 Q9Y483 P84022 MTF2 SMAD3 0.332 15231748 Q9Y483 Q15022 MTF2 SUZ12 0.396 20123894,27705803 Q9Y483 A6NHQ4 MTF2 C17ORF96 0.236 27705803 Q9Y483 Q15717 MTF2 ELAVL1 0.126 19322201 Q9Y483 Q09028 MTF2 RBBP4 0.236 27705803