PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RFWD2 GRWD1 17041588 intact exp G G G G G GP G G GP G G G G G G G GP G G G G G G G G G G G G YWHAB RFWD2 21135113 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G MVP RFWD2 25117710,15994960 biogrid,intact exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G CUL3 RFWD2 19295130 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G CCT4 RFWD2 24298020,16497536 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G TCEB2 RFWD2 19295130 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MDM4 RFWD2 20333547 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G ELAVL1 RFWD2 19322201 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 VPRBP 19295130 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G ATF6 RFWD2 25609649 intact exp G G G G G GP G G G G G G G G G G GP G G G GP G G G G G GP G G FOS RFWD2 26186194,26496610,25609649 biogrid,intact exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G HSPA8 RFWD2 16497536 biogrid exp P P P P P CUL2 RFWD2 19295130 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G DMC1 RFWD2 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G RFWD2 RFWD2 16931761,23289756,12615916,21135113 hprd,biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 BTBD2 19295130 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G ETS2 RFWD2 25117710,26496610 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G ETV4 RFWD2 20062082,25117710,21572435 biogrid,intact exp P P G P G G GP G P WDR5 RFWD2 17041588 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SFN RFWD2 21625211,20843328 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ETV5 RFWD2 20062082,25117710,26186194,21572435 biogrid,intact exp G G G G G GP G G P G G G G G G G GP G G G GP G G G G G GP G G JUNB RFWD2 25117710 biogrid,intact exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 COPS4 19295130 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 KLHL42 19295130 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G G G G RFWD2 SIPA1 11461903 hprd,biogrid exp G G G G P G G G G G G G G P G G G G G HSPA6 RFWD2 16497536 biogrid exp G G G G G P G G GP G G G G G G GP G G G GP G G G G G GP G G ETV1 RFWD2 20062082,25117710,26186194,21572435 biogrid,intact,dip exp G G G G G G G G G G G G G G G G G G G G G G G G G G G RFWD2 COPS7A 19295130 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G ZNF397 RFWD2 26186194 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 LRR1 19295130 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G FOSL2 RFWD2 26186194,26496610 biogrid,intact exp G G G G G GP G G GP G G G G G G GP G G G GP G G G G G GP G SKP1 RFWD2 19295130 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G COPS2 RFWD2 12466024,19295130 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G UBE2D2 RFWD2 16931761,21625211,15103385 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 PARP4 25117710 biogrid,intact exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G HSPA2 RFWD2 16497536 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 COPS7B 19295130 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 RB1CC1 23289756 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G YWHAZ RFWD2 20843328 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G STK40 RFWD2 26186194 biogrid exp G G G G G G G G G G GP G G G G G GP G G CCT8 RFWD2 16497536 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G PTPN1 RFWD2 23439647 biogrid exp G G G G G G G G GP G G G G G G G G G G G GP G G G G G GP G G UBE2D1 RFWD2 25117710,21625211 biogrid exp G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 TRIB3 25117710,26186194,21572435 biogrid,intact exp, ortho G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G PTPN11 RFWD2 23269672 biogrid exp, ortho G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G REG1A RFWD2 23269672 biogrid exp, ortho GP G G G GP G RFWD2 TRIB2 25311538 biogrid,intact exp, ortho G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 TRIB1 25117710 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CRTC2 RFWD2 17805301 biogrid exp, ortho G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RBX1 RFWD2 14739464,19295130, 25402006 biogrid exp, pred G G G G G GP G G G G G G G G G G GP G G G GP G G G G G G G G RFWD2 DDA1 19295130,25117710, 25402006 biogrid,intact exp, pred G G G G G GP G G GP G G G G G G GP G G GP G G G G G GP G G TP53 RFWD2 16931761,21625211,15103385,23736031, 25402006 hprd,biogrid,i2d,mint,intact exp, pred G G G G G G G G G G G G G G G G G G G G GP G G G G G G G G ERCC8 RFWD2 19295130, 25402006 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TCP1 RFWD2 16497536, 25402006 biogrid exp, pred P P P P P JUN RFWD2 14739464,25117710,12615916,15994960,25609649, 25402006 hprd,biogrid,i2d,mint,intact exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 COPS5 19295130, 25402006, 21836163 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G FOXO1 RFWD2 18815134, 21836163 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G MDM2 RFWD2 20333547, 25402006 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G CUL1 RFWD2 19295130, 25402006 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G DDB1 RFWD2 17041588,14739464,19295130,17079684,25117710,16949367, 25402006, 21836163 biogrid,intact exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G CUL4B RFWD2 17041588,19295130, 25402006 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G COPS6 RFWD2 19295130,21625211, 25402006 biogrid,intact exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G CCT6A RFWD2 16497536, 25402006 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G DET1 RFWD2 14739464,25117710,21572435,17452440, 25402006 hprd,biogrid,i2d,intact exp, pred G G G G G GP G G G G G G G G G G GP G G G GP G G G G G GP G G RFWD2 DDB2 19295130, 25402006 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G GP G G ETS1 RFWD2 25117710, 25402006 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RFWD2 DCAF11 19295130, 25402006 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G CCT2 RFWD2 16497536, 25402006 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 RCHY1 20333547, 25402006 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G G G G G G G GP G G CCT5 RFWD2 16497536, 25402006 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G CCT3 RFWD2 16497536, 25402006 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 CCT7 16497536, 25402006 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G CUL4A RFWD2 17041588,14739464,19295130,17079684,25117710,21145461, 25402006, 21836163 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G JUND RFWD2 23289756,12615916, 21836163 hprd,biogrid,mint,intact exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 COPS3 19295130, 25402006, 21836163 biogrid exp, pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 COPS8 12466024,19295130, 21836163 biogrid exp, pred G G G G G GP G G G G G G G G G G GP G G G G G G G G G G G G FASN RFWD2 ortho G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 UNC13A 21836163 pred G GP G P G GP G P P RFWD2 DDIT4 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G IQGAP1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G TXN RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G ARHGAP12 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 MAP3K3 25402006 pred G G G G G GP G G G G G G G G G G GP G G G GP G G G G G GP G G RFWD2 GOLPH3 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 HDAC2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G GOLGA2 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 TOPORS 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G ARFIP1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G SNAP29 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RGS6 RFWD2 21836163 pred G GP G P GP P P PACS1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G BCL2 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G G G G CDK2 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G PARP1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RABEP1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G ARFGAP1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G PIAS2 RFWD2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RFWD2 HCN2 21836163 pred G G G G G G CAND1 RFWD2 25402006 pred G G G G G G G G GP G G G G G G G G G G G G G G G G G G G G SNAP91 RFWD2 21836163 pred G GP G P G GP G G G G CHEK1 RFWD2 25402006 pred G G G G RAB11B RFWD2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GOLIM4 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RRM2 RFWD2 25402006 pred G G G G G G G G GP G G G G G G G G G G G G G G G G G G G G RFWD2 ARFGEF2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G WDTC1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G NF2 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 KAT2B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G ARHGAP24 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 CREBBP 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G GCC2 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RELA RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 PACSIN2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G ARF3 RFWD2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RFWD2 CD2AP 21836163 pred G G G G P G G GP G G G G G G GP G G G GP G G G G G GP G CDKN1B RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G UBE2I RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G SPINT2 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G GP G G RFWD2 SEC31B 21836163 pred G G G GP G GP G G G G G GP G P G G GP G TOP1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 ING2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G SEC24C RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G PIAS4 RFWD2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G STAT1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G G G G RFWD2 COG5 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G USO1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G DCAF12 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G G G G G G G GP G G CYTH1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G G G G G G G GP G G GOSR1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 RAB6B 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G GOLGA3 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G MAP4K3 RFWD2 21836163 pred G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G CCNH RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G G G G G G G GP G G MAPK8 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 SCYL1 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G S100A1 RFWD2 25402006 pred G G G GP G G GP G G G G G G GP G G G GP G G G G GP G G CDK1 RFWD2 25402006 pred G G G G GP G G G G GP G G GP G MAPK9 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G DCAF10 RFWD2 25402006 pred G G G G G GP G G G G G G G G G G GP G G G G G G G G G GP G G VPS26A RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 ARHGAP26 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G GPS1 RFWD2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SEC23B RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 EXOC2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G LMAN2 RFWD2 21836163 pred G G G G G GP G G G G G G G G G G GP G G G GP G G G G G GP G G RFWD2 SIRT1 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G NFKBIA RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G CDC25C RFWD2 25402006 pred G G P GP G P P G P G G SEC31A RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 SIN3A 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G EIF3E RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 EPS15L1 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 NRBP1 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 RACGAP1 21836163 pred G G G G G G G GP G G G G G G G G G G GP G G G G G GP G G KDELR1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G SEC61A1 RFWD2 21836163 pred G G G G G GP G G G G G G G G G G GP G G G GP G G G G G GP G G RFWD2 BARD1 25402006 pred G G P GP G G G P G P G G G GP G G RBM39 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G ARF4 RFWD2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DCAF8 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G PPP2R2B RFWD2 25402006 pred G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G TNFRSF1B RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G GP G G G G G GP G CSNK1A1 RFWD2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RFWD2 VPS29 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G YIF1A RFWD2 21836163 pred G G G G G G G G GP G G G G G G G G G G G GP G G G G G GP G G RBBP7 RFWD2 23023127 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 GGA1 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G ATR RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G G G G UBE3A RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G MEST RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G G G G G G G GP G G SEC24A RFWD2 21836163 pred G G G G G G G G GP G G G G G G G G G G G GP G G G G G GP G G PITPNA RFWD2 21836163 pred G G G G G G G G GP G G G G G G G G G G G GP G G G G G G G G NR3C1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G NFATC2 RFWD2 25402006 pred G G G P G GP G G G G G G G P G GP G G G G G GP G G HDAC1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G BNIP1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G GP G G TMED2 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G MAP3K1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G AGFG1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G GOLGB1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RBBP4 RFWD2 23023127 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G UBXN1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G COPE RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G EHBP1L1 RFWD2 21836163 pred G G G G P G G GP G G G G P G GP G G G G GP G SEC24B RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G SEC23A RFWD2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SEC24D RFWD2 21836163 pred G G G G P G G GP G G G G G G P G G G G G G G G GP G G SLC6A12 RFWD2 21836163 pred G G G G G GP G G P G G G G G G GP G G G GP G G G G P G G CTBP1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G ATF3 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G CDKN1A RFWD2 25402006 pred G G G G G G G G GP G G G G G G G G G G G GP G G G G G G G G GBP1 RFWD2 21836163 pred G G G G GP G G GP G G G G G G G GP G G G G G G G G G G SMAD2 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 YIPF5 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G VPS41 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G TP73 RFWD2 25402006 pred G G G G G CORO7 RFWD2 21836163 pred G G G GP GP G G G G GP GP G G P G CORO7 RFWD2 21836163 pred G G G GP GP G G G G GP GP G G P G RFWD2 SH3KBP1 21836163 pred G G G G G GP G G G G G G G G G G GP G G G GP G G G G G G G G TRIM23 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G MAPK1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G CNTRL RFWD2 21836163 pred G G G G G GP G G GP G G G G G G GP G G G P G G G G GP G CTNNB1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G EP300 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G MNAT1 RFWD2 25402006 pred G G G GP G G GP G G G G G G GP G G P G G G G G GP TBP RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 CDT1 25402006 pred G G P G GP G P G G G P G GP G FBXO11 RFWD2 25402006 pred G G G G G GP G G G G G G G G G G GP G G G GP G G G G G G G G DCAF6 RFWD2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G COPB2 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G ABL1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 TP63 25402006 pred G G G G G G G G G G G G G G G G G G G GP G G G G G G STX5 RFWD2 21836163 pred G G G G G GP G G G G G G G G G G GP G G G GP G G G G G GP G G ATM RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G TG RFWD2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G NEDD8 RFWD2 25402006, 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G MTA1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G SUMO1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 ING4 25402006 pred G G G G G GP G G G G G G G G G G GP G G GP G G G G G GP G G RFWD2 ARFGEF1 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G HSP90AA1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G G G G ACTR1A RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G CHSY1 RFWD2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G AP2A1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 VRK1 25402006 pred G G G G GP G G G G G G GP G G P G G G G GP G E2F1 RFWD2 25402006 pred G G G G GP G G GP G G G G G G GP G G G P G G GP G G LMAN1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 PHIP 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G MAN2A1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 DTL 25402006 pred G G P G G P G P G G G G RFWD2 TRPC4AP 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G PML RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G TMED10 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 ERGIC1 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G HUWE1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G COG2 RFWD2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLK1 RFWD2 25402006 pred G G G P G G GP G G GP G G G GP G G G P G RFWD2 DCAF4 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 CGN 21836163 pred G P GP G G G G G P G G P G G G GP G G RFWD2 MCFD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G PEX11B RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G OSBP RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 SYT11 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G G G G G G G G G COPA RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G SEC13 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G AMPH RFWD2 21836163 pred G G G G GP G G GP G G G G G GP G G G G G G G G G G G ARHGAP19 RFWD2 21836163 pred G G G G GP G G GP G G G G G G G GP G G G G G GP G G CDK7 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G GP G G G GP G G G G G GP G G RFWD2 ING1 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G SLC14A2 RFWD2 21836163 pred P G P G P P P BRCA1 RFWD2 25402006 pred G G P P G P P P G PLIN3 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 ING5 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G MTA2 RFWD2 25402006 pred P P G P P P ELL RFWD2 25402006 pred G G G G P P P G G G GP G G P G G PSME3 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RNF20 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G COPB1 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 DCAF5 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RBP2 RFWD2 21836163 pred G G G G G G G G G G G G G G RB1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 SAR1A 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G SP1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 GOLGA1 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G RFWD2 ARAP1 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G EXOC3 RFWD2 21836163 pred G G G G G GP G G G G G G G G G G GP G G GP G G G G G G G AR RFWD2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G CSNK2A1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G TGOLN2 RFWD2 21836163 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G PIAS1 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G PTK2 RFWD2 25402006 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G GP G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8NHY2 - 14739464 - C 5 Q8NHY2 P05412 - 14739464 - X 2 Q8NHY2 - 14739464 - C 4 Q8NHY2 Q7L5Y6-2 - 14739464 - X 2 Q8NHY2 Q7L5Y6-2 - 14739464 - X 2 Q8NHY2 - 15103385 - X 2 Q8NHY2 anti tag coimmunoprecipitation 14739464 association C 5 Q8NHY2 mass spectrometry studies of complexes 14739464 association C 5 Q8NHY2 anti tag coimmunoprecipitation 21572435 - C 6 Q8NHY2 Q8K4K2 anti tag coimmunoprecipitation 21572435 physical association X 2 Q8NHY2 P41164 anti tag coimmunoprecipitation 21572435 physical association X 2 Q8NHY2 P50549 anti bait coimmunoprecipitation 21572435 physical association X 2 Q8NHY2 P50549 anti bait coimmunoprecipitation 21572435 physical association X 2 Q8NHY2 P50549 anti tag coimmunoprecipitation 21572435 physical association X 2 Q8NHY2 P50549 anti tag coimmunoprecipitation 21572435 physical association X 2 Q8NHY2 Q9D0A0 anti tag coimmunoprecipitation 21572435 physical association X 2 Q8NHY2 P28322 anti tag coimmunoprecipitation 21572435 physical association X 2 Q8NHY2 Q9CXC9 anti tag coimmunoprecipitation 21572435 physical association X 2 Q8NHY2 anti bait coimmunoprecipitation 21625211 association C 3 Q8NHY2 anti bait coimmunoprecipitation 17041588 association C 14 Q8NHY2 tandem affinity purification 25117710 association C 13 Q8NHY2 P05412 coimmunoprecipitation 12615916 physical association X 2 Q8NHY2 P17535 coimmunoprecipitation 12615916 physical association X 2 Q8NHY2 K7PPA8 experimental interaction detection 15103385 ubiquitination reaction X 2 Q8NHY2 K7PPA8 anti tag coimmunoprecipitation 15103385 physical association X 2 Q8NHY2 K7PPA8 pull down 15103385 direct interaction X 2 Q8NHY2 K7PPA8 anti bait coimmunoprecipitation 15103385 physical association X 2 Q8NHY2 Q81R77 two hybrid pooling approach 20711500 physical association X 2 Q8NHY2 P31947 anti tag coimmunoprecipitation 20843328 physical association X 2 Q8NHY2 P31947 pull down 20843328 physical association X 2 Q8NHY2 Q7L5N1 anti tag coimmunoprecipitation 21625211 direct interaction X 2 Q8NHY2 P15036 anti tag coimmunoprecipitation 25117710 physical association X 2 Q8NHY2 anti tag coimmunoprecipitation 25117710 association C 7 Q8NHY2 anti tag coimmunoprecipitation 17041588 association C 3 Q8NHY2 anti bait coimmunoprecipitation 21625211 association C 3 Q8NHY2 molecular sieving 21625211 physical association C 3 Q8NHY2 molecular sieving 21625211 physical association C 3 Q8NHY2 anti bait coimmunoprecipitation 21625211 association C 3 Q8NHY2 anti bait coimmunoprecipitation 20843328 physical association C 3 Q8NHY2 Q5NET3 two hybrid pooling approach 20711500 physical association X 2 Q8NHY2 P14921 anti tag coimmunoprecipitation 25117710 physical association X 2 Q8NHY2 P14921 pull down 25117710 physical association X 2 Q8NHY2 P14921 anti bait coimmunoprecipitation 25117710 physical association X 2 Q8NHY2 P14921 anti tag coimmunoprecipitation 25117710 physical association X 2 Q8NHY2 Q92519 fluorescence microscopy 25311538 colocalization X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CUL3 RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_221730|BIOGRID_221292 prey|bait bait|prey RFWD2 DDB2 MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221736 bait prey CUL1 RFWD2 MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221673 prey bait RFWD2 COPS5 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_221708|BIOGRID_221667 prey|bait bait|prey CRTC2 RFWD2 MI:0004(affinity chromatography technology) 17805301 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_118733 prey bait RBX1 RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 14739464,19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_87095|BIOGRID_221672 prey|prey bait|bait DDB1 RFWD2 MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0401(biochemical)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation) 14739464,16949367,17041588,17079684,19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact) HPRD_39921|BIOGRID_122841|BIOGRID_200203|BIOGRID_221735|BIOGRID_87093|UniProt_87652 -|bait|bait|prey|prey|prey -|prey|prey|bait|bait|bait HSPA2 RFWD2 MI:0004(affinity chromatography technology) 16497536 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_124672 prey bait MDM2 RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20333547 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_153682|BIOGRID_153683 bait|prey prey|bait CCT4 RFWD2 MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down) 16497536,24298020 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_307581|BIOGRID_124679|BIOGRID_307584 prey|prey|prey bait|bait|bait CCT8 RFWD2 MI:0004(affinity chromatography technology) 16497536 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_124677 prey bait DET1 RFWD2 MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 14739464,21572435 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid) HPRD_14742|BIOGRID_87090|BIOGRID_87092|BIOGRID_164997 -|bait|prey|prey -|prey|bait|bait RFWD2 CCT7 MI:0004(affinity chromatography technology) 16497536 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_124678 bait prey RFWD2 COPS8 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12466024,19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_134297|BIOGRID_221671 bait|bait prey|prey RFWD2 COPS7A MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_221669|BIOGRID_221717 bait|prey prey|bait HSPA8 RFWD2 MI:0004(affinity chromatography technology) 16497536 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_124670 prey bait MDM4 RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20333547 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_153686|BIOGRID_153687 bait|prey prey|bait TCP1 RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16497536 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_124682|BIOGRID_124681|BIOGRID_124674 prey|prey|prey bait|bait|bait RFWD2 COPS3 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_221665|BIOGRID_221675 bait|prey prey|bait RFWD2 BTBD2 MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221731 bait prey RFWD2 COPS4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_221666|BIOGRID_221686 bait|prey prey|bait CCT2 RFWD2 MI:0004(affinity chromatography technology) 16497536 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_124680 prey bait RFWD2 DDA1 MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221637 prey bait YWHAZ RFWD2 MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0428(imaging technique) 20843328 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_153710|BIOGRID_153711|BIOGRID_153712|BIOGRID_153713 prey|prey|bait|bait bait|bait|prey|prey WDR5 RFWD2 MI:0004(affinity chromatography technology) 17041588 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_129032 prey bait COPS2 RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12466024,19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_134296|BIOGRID_221664 prey|prey bait|bait SKP1 RFWD2 MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221674 prey bait ELAVL1 RFWD2 MI:0096(pull down) 19322201 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_186374 bait prey RFWD2 SIPA1 MI:0018(two hybrid)|MI:0018(two hybrid) 11461903 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_10417|BIOGRID_77836 -|bait -|prey SFN RFWD2 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 20843328,21625211 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association) (intact)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_108292|BIOGRID_255263|UniProt_108294|UniProt_108293|UniProt_114022|UniProt_114021|UniProt_114017 bait|prey|bait|prey|neutral component|neutral component|bait prey|bait|prey|bait|neutral component|neutral component|prey UBE2D2 RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15103385,16931761,21625211 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_225882|BIOGRID_255265|BIOGRID_225703 prey|prey|prey bait|bait|bait RFWD2 LRR1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_221616|BIOGRID_221729 prey|bait bait|prey RFWD2 TRIB3 MI:0004(affinity chromatography technology) 21572435 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_164998 bait prey RFWD2 RCHY1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20333547 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_153691|BIOGRID_153690 prey|bait bait|prey UBC RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0428(imaging technique)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology) 12466024,16931761,20843328,21135113,21625211,21890473 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_174144|BIOGRID_134295|BIOGRID_153714|BIOGRID_255258|BIOGRID_153947|BIOGRID_122958 bait|prey|prey|prey|prey|prey prey|bait|bait|bait|bait|bait RFWD2 DCAF11 MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221739 bait prey RFWD2 RB1CC1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 23289756 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_248881|BIOGRID_248883|BIOGRID_248885 bait|prey|bait prey|bait|prey NRF1 RFWD2 MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_295322 bait prey HSPA6 RFWD2 MI:0004(affinity chromatography technology) 16497536 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_124671 prey bait TCEB2 RFWD2 MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221728 prey bait CUL4A RFWD2 MI:0006(anti bait coimmunoprecipitation)|MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0401(biochemical) 14739464,17041588,17079684,19295130,21145461,24298020 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) UniProt_87648|HPRD_39921|BIOGRID_221301|BIOGRID_129008|BIOGRID_202972|BIOGRID_221733|BIOGRID_87094|BIOGRID_307585|BIOGRID_200212 bait|-|bait|bait|bait|prey|prey|prey|bait prey|-|prey|prey|prey|bait|bait|bait|prey PTPN11 RFWD2 MI:0004(affinity chromatography technology) 23269672 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_247471 bait prey MVP RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15994960 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_199106|BIOGRID_199104 bait|prey prey|bait c-Jun RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0019(coimmunoprecipitation)|MI:0493(in vivo)|MI:0019(coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0019(coimmunoprecipitation) 12615916,14739464,15994960 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(biogrid)|(intact) BIOGRID_90216|BIOGRID_199107|MINT_49021|HPRD_332|MINT_80812|BIOGRID_87096|UniProt_73329 bait|prey|prey|-|prey|prey|prey prey|bait|bait|-|bait|bait|bait CCT3 RFWD2 MI:0004(affinity chromatography technology) 16497536 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_124673 prey bait FOXO1 RFWD2 MI:0004(affinity chromatography technology) 18815134 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_116421 prey bait CUL4B RFWD2 MI:0006(anti bait coimmunoprecipitation)|MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17041588,19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|-|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0468(hprd)|(biogrid)|(biogrid) UniProt_87648|HPRD_39921|BIOGRID_129020|BIOGRID_221734 bait|-|bait|prey prey|-|prey|bait RFWD2 KLHDC5 MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221732 bait prey p53 RFWD2 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0492(in vitro)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0045(experimental interaction detection)|MI:0045(experimental interaction detection)|MI:0045(experimental interaction detection)|MI:0045(experimental interaction detection)|MI:0006(anti bait coimmunoprecipitation) 15103385,16931761,21625211,23736031 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0220(ubiquitination reaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0220(ubiquitination reaction)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0220(ubiquitination reaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0914(association) (biogrid)|MI:0471(mint)|(biogrid)|MI:0471(mint)|(biogrid)|MI:0471(mint)|(biogrid)|(biogrid)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(biogrid)|MI:0471(mint)|(intact)|(intact)|(intact)|(intact)|(intact) BIOGRID_200782|MINT_55213|BIOGRID_200777|MINT_55212|BIOGRID_200775|MINT_55211|BIOGRID_200776|BIOGRID_281097|MINT_55214|BIOGRID_255254|MINT_57881|MINT_57882|HPRD_18298|MINT_57880|BIOGRID_122960|MINT_57879|UniProt_77504|UniProt_77503|UniProt_77506|UniProt_77505|UniProt_114023 prey|bait|bait|bait|bait|prey|prey|bait|unspecified role|prey|bait|unspecified role|-|bait|prey|prey|prey|unspecified role|bait|bait|prey bait|prey|prey|prey|prey|bait|bait|prey|unspecified role|bait|prey|unspecified role|-|prey|bait|bait|bait|unspecified role|prey|prey|bait YWHAB RFWD2 MI:0096(pull down)|MI:0096(pull down) 21135113 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_153944|BIOGRID_153946 bait|prey prey|bait CCT6A RFWD2 MI:0004(affinity chromatography technology) 16497536 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_124675 prey bait CUL2 RFWD2 MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221727 prey bait ERCC8 RFWD2 MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221737 prey bait ETV4 RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20062082,21572435 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_165000|BIOGRID_142641 prey|prey bait|bait COPS6 RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 19295130,21625211 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(intact) BIOGRID_255252|BIOGRID_255253|BIOGRID_221668|UniProt_114025|BIOGRID_221697|UniProt_114022|UniProt_114021|UniProt_114024|UniProt_114023 bait|prey|prey|prey|bait|neutral component|neutral component|bait|prey prey|bait|bait|bait|prey|neutral component|neutral component|prey|bait UBE2D1 RFWD2 MI:0004(affinity chromatography technology) 21625211 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_255264 prey bait RFWD2 COPS7B MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221670 bait prey RFWD2 VPRBP MI:0004(affinity chromatography technology) 19295130 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_221738 bait prey JUND RFWD2 MI:0018(two hybrid)|MI:0493(in vivo)|MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0004(affinity chromatography technology) 12615916,23289756 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0468(hprd)|MI:0471(mint)|MI:0471(mint)|(intact)|(biogrid) BIOGRID_248882|HPRD_376|MINT_49022|MINT_80813|UniProt_73330|BIOGRID_90217 prey|-|prey|prey|prey|bait bait|-|bait|bait|bait|prey ETV1 RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20062082,21572435 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_164996|BIOGRID_142640|BIOGRID_164999 prey|prey|prey bait|bait|bait REG1A RFWD2 MI:0004(affinity chromatography technology) 23269672 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_247472 bait prey ETV5 RFWD2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 20062082,21572435 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_142638|BIOGRID_142639|BIOGRID_165001 bait|prey|prey prey|bait|bait CCT5 RFWD2 MI:0004(affinity chromatography technology) 16497536 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_124676 prey bait

PPI - HINT Gene A Gene B PMID Method Quality FOS RFWD2 26496610,25609649,26186194,26496610,25609649 0007,0676,0004,0004,0004 HT TP53 RFWD2 15103385,15103385,15103385,21625211,15103385,15103385 0019,0007,0006,0006,0096,0045 LC JUN RFWD2 15994960,14739464,25117710,25609649,25609649,25609649,12615916,14739464,12615916,25117710 0004,0004,0004,0676,0004,0006,0004,0019,0019,0007 LC,HT ETS2 RFWD2 26496610,25117710,25117710,26496610,25117710,26871468,25117710 0004,0415,0676,0007,0004,0004,0007 HT,LC FOSL2 RFWD2 26496610,26186194,26496610 0007,0004,0004 HT ATF6 RFWD2 25609649,25609649 0676,0004 HT SFN RFWD2 21625211,21625211,20843328,20843328,20843328,21625211 0071,0006,0096,0007,0006,0415 LC ETV5 RFWD2 25117710,25117710,26186194,21572435,20062082,25117710 0004,0676,0004,0004,0004,0007 LC,HT ETV4 RFWD2 21572435,25117710,20062082,25117710 0004,0004,0004,0676 LC ETV1 RFWD2 21572435,21572435,25117710,25117710,26186194,21572435,20062082 0006,0007,0004,0676,0004,0004,0004 LC,HT CCT4 RFWD2 24298020,16497536,24298020 0004,0004,0415 LC UBE2D1 RFWD2 25117710,21625211 0096,0096 LC UBE2D2 RFWD2 21625211,15103385,16931761 0096,0096,0096 LC RBX1 RFWD2 19295130,14739464 0004,0004 LC CUL4A RFWD2 14739464,25117710,17041588,21145461,17041588,19295130,17079684,25117710 0004,0004,0004,0004,0006,0004,0004,0007 LC,HT CUL4B RFWD2 17041588,19295130 0004,0004 LC DMC1 RFWD2 26186194 0004 HT MVP RFWD2 25117710,15994960,25117710 0004,0004,0676 LC DDB1 RFWD2 25117710,25117710,14739464,17041588,19295130,16949367,17079684,25117710 0676,0004,0004,0007,0004,0004,0004,0007 LC Q53GA5 RFWD2 15103385,23736031,15103385,15103385,21625211,16931761 0004,0004,0415,0096,0004,0004 LC Q59EL2 RFWD2 12466024,19295130 0401,0004 LC COPS6 RFWD2 21625211,21625211,19295130,21625211,21625211 0401,0006,0004,0007,0004 LC DET1 RFWD2 17452440,25117710,25117710,14739464,14739464,21572435,25117710 0004,0676,0004,0004,0019,0004,0007 LC STK40 RFWD2 26186194 0004 HT ZNF397 RFWD2 26186194 0004 HT RFWD2 RFWD2 12615916,23289756,23289756 0004,0004,0090 LC RFWD2 TRIB3 21572435,25117710,26186194,25117710 0004,0004,0004,0676 LC,HT RFWD2 TRIB1 25117710,27041596,27041596,25117710 0004,0114,0004,0676 LC RFWD2 COPS8 12466024,19295130 0401,0004 LC RFWD2 DDA1 25117710,19295130,25117710 0004,0004,0676 LC FOS RFWD2 26496610,25609649,26186194,26496610,25609649 0007,0676,0004,0004,0004 HT JUN RFWD2 25609649,25609649,25609649 0676,0004,0006 HT ETS2 RFWD2 26496610,26496610 0004,0007 HT FOSL2 RFWD2 26496610,26186194,26496610 0007,0004,0004 HT ATF6 RFWD2 25609649,25609649 0676,0004 HT ETV5 RFWD2 26186194 0004 HT ETV1 RFWD2 26186194 0004 HT CUL4A RFWD2 21145461 0004 HT DMC1 RFWD2 26186194 0004 HT STK40 RFWD2 26186194 0004 HT ZNF397 RFWD2 26186194 0004 HT RFWD2 TRIB3 26186194 0004 HT TP53 RFWD2 15103385,15103385,15103385,21625211,15103385,15103385 0019,0007,0006,0006,0096,0045 LC JUN RFWD2 15994960,14739464,25117710,12615916,14739464,12615916,25117710 0004,0004,0004,0004,0019,0019,0007 LC ETS2 RFWD2 25117710,25117710,25117710,26871468,25117710 0415,0676,0004,0004,0007 LC SFN RFWD2 21625211,21625211,20843328,20843328,20843328,21625211 0071,0006,0096,0007,0006,0415 LC ETV5 RFWD2 25117710,25117710,21572435,20062082,25117710 0004,0676,0004,0004,0007 LC ETV4 RFWD2 21572435,25117710,20062082,25117710 0004,0004,0004,0676 LC ETV1 RFWD2 21572435,21572435,25117710,25117710,21572435,20062082 0006,0007,0004,0676,0004,0004 LC CCT4 RFWD2 24298020,16497536,24298020 0004,0004,0415 LC UBE2D1 RFWD2 25117710,21625211 0096,0096 LC UBE2D2 RFWD2 21625211,15103385,16931761 0096,0096,0096 LC RBX1 RFWD2 19295130,14739464 0004,0004 LC CUL4A RFWD2 14739464,25117710,17041588,17041588,19295130,17079684,25117710 0004,0004,0004,0006,0004,0004,0007 LC CUL4B RFWD2 17041588,19295130 0004,0004 LC MVP RFWD2 25117710,15994960,25117710 0004,0004,0676 LC DDB1 RFWD2 25117710,25117710,14739464,17041588,19295130,16949367,17079684,25117710 0676,0004,0004,0007,0004,0004,0004,0007 LC Q53GA5 RFWD2 15103385,23736031,15103385,15103385,21625211,16931761 0004,0004,0415,0096,0004,0004 LC Q59EL2 RFWD2 12466024,19295130 0401,0004 LC COPS6 RFWD2 21625211,21625211,19295130,21625211,21625211 0401,0006,0004,0007,0004 LC DET1 RFWD2 17452440,25117710,25117710,14739464,14739464,21572435,25117710 0004,0676,0004,0004,0019,0004,0007 LC RFWD2 RFWD2 12615916,23289756,23289756 0004,0004,0090 LC RFWD2 TRIB3 21572435,25117710,25117710 0004,0004,0676 LC RFWD2 TRIB1 25117710,27041596,27041596,25117710 0004,0114,0004,0676 LC RFWD2 COPS8 12466024,19295130 0401,0004 LC RFWD2 DDA1 25117710,19295130,25117710 0004,0004,0676 LC TP53 RFWD2 15103385,15103385,15103385,15103385,15103385 0019,0007,0006,0096,0045 LC JUN RFWD2 14739464,12615916,14739464,12615916 0004,0004,0019,0019 LC ETS1 RFWD2 25117710,25117710,25117710,25117710 0006,0096,0415,0007 LC ETS2 RFWD2 25117710,25117710,25117710,25117710 0415,0676,0004,0007 LC JUND RFWD2 12615916,12615916,23289756 0019,0004,0018 LC TCP1 RFWD2 16497536,16497536 0004,0401 LC SFN RFWD2 21625211,21625211,21625211 0071,0006,0415 LC CDKN1B RFWD2 26254224,26254224,26254224,26254224 0096,0415,0401,0004 LC CCT4 RFWD2 24298020,24298020 0004,0415 LC Q53GA5 RFWD2 15103385,15103385,15103385 0004,0415,0096 LC Q59EL2 RFWD2 12466024 0401 LC COPS6 RFWD2 21625211,21625211,21625211,21625211 0401,0006,0007,0004 LC DET1 RFWD2 14739464,14739464 0004,0019 LC RFWD2 RFWD2 21135113,16931761,23289756,23289756 0415,0415,0004,0090 LC RFWD2 RB1CC1 23289756,23289756,23289756 0096,0018,0090 LC RFWD2 TRIB2 25311538,25311538 0416,0004 LC RFWD2 SIPA1 11461903 0018 LC RFWD2 TRIB1 27041596,27041596 0114,0004 LC RFWD2 COPS8 12466024 0401 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8NHY2 O15151 RFWD2 MDM4 0.376 20333547 Q8NHY2 Q8N2I9 RFWD2 STK40 0.126 26186194 Q8NHY2 Q8NF99 RFWD2 ZNF397 0.126 26186194 Q8NHY2 P11142 RFWD2 HSPA8 0.21 16497536 Q8NHY2 P17066 RFWD2 HSPA6 0.21 16497536 Q8NHY2 P40227 RFWD2 CCT6A 0.21 16497536 Q8NHY2 P48643 RFWD2 CCT5 0.21 16497536 Q8NHY2 P49368 RFWD2 CCT3 0.21 16497536 Q8NHY2 P50990 RFWD2 CCT8 0.21 16497536 Q8NHY2 P54652 RFWD2 HSPA2 0.21 16497536 Q8NHY2 P61964 RFWD2 WDR5 0.126 17041588 Q8NHY2 P63208 RFWD2 SKP1 0.126 19295130 Q8NHY2 P78371 RFWD2 CCT2 0.21 16497536 Q8NHY2 Q12778 RFWD2 FOXO1 0.21 18815134 Q8NHY2 Q13216 RFWD2 ERCC8 0.126 19295130 Q8NHY2 Q13616 RFWD2 CUL1 0.126 19295130 Q8NHY2 Q13617 RFWD2 CUL2 0.126 19295130 Q8NHY2 Q15370 RFWD2 TCEB2 0.126 19295130 Q8NHY2 Q53ET0 RFWD2 CRTC2 0.21 17805301 Q8NHY2 Q5NET3 RFWD2 FADE 0.126 20711500 Q8NHY2 Q8K4K4 RFWD2 TRIB1 0.309 23884858 Q8TEB1 Q8NHY2 DCAF11 RFWD2 0.126 19295130 Q92466 Q8NHY2 DDB2 RFWD2 0.126 19295130 Q96FS4 Q8NHY2 SIPA1 RFWD2 0.309 11461903 Q99832 Q8NHY2 CCT7 RFWD2 0.21 16497536 Q9BQ67 Q8NHY2 GRWD1 RFWD2 0.126 17041588 Q9BX70 Q8NHY2 BTBD2 RFWD2 0.126 19295130 Q9H9Q2 Q8NHY2 COPS7B RFWD2 0.126 19295130 Q9P2K6 Q8NHY2 KLHL42 RFWD2 0.126 19295130 Q9Y4B6 Q8NHY2 VPRBP RFWD2 0.126 19295130 Q8TDY2 Q8NHY2 RB1CC1 RFWD2 0.671 23289756 Q8NHY2 Q7L5Y6 RFWD2 DET1 0.757 14739464,21572435,25117710 Q8NHY2 P05451 RFWD2 REG1A 0.21 23269672 Q8NHY2 P17987 RFWD2 TCP1 0.309 16497536 Q8NHY2 P17275 RFWD2 JUNB 0.376 25117710 Q8NHY2 Q7L5N1 RFWD2 COPS6 0.472 21625211,19295130 Q8NHY2 P51668 RFWD2 UBE2D1 0.523 21625211,25117710 Q8NHY2 P62877 RFWD2 RBX1 0.309 14739464,19295130 Q8NHY2 P61201 RFWD2 COPS2 0.236 19295130,12466024 Q8NHY2 P63104 RFWD2 YWHAZ 0.623 20843328 Q9UKK3 Q8NHY2 PARP4 RFWD2 0.376 25117710 Q99627 Q8NHY2 COPS8 RFWD2 0.236 19295130,12466024 Q8NHY2 P18850 RFWD2 ATF6 0.236 25609649 Q8NHY2 Q16531 RFWD2 DDB1 0.794 17079684,25117710,17041588,14739464,16949367,19295130 Q8NHY2 P46527 RFWD2 CDKN1B 0.74 26254224 Q8NHY2 P41161 RFWD2 ETV5 0.787 20062082,26186194,21572435,25117710 Q8NHY2 P50991 RFWD2 CCT4 0.569 16497536,24298020 Q8NHY2 P62837 RFWD2 UBE2D2 0.671 16931761,21625211,15103385 Q8NHY2 P15408 RFWD2 FOSL2 0.332 26496610,26186194 Q8NHY2 P05412 RFWD2 JUN 0.837 25609649,12615916,25117710,15994960,14739464 Q8NHY2 P43268 RFWD2 ETV4 0.61 20062082,21572435,25117710 Q8NHY2 Q13619 RFWD2 CUL4A 0.801 17079684,21145461,25117710,17041588,14739464,19295130 Q8NHY2 P15036 RFWD2 ETS2 0.872 26871468,25117710,26496610 Q8NHY2 Q8NHY2 RFWD2 RFWD2 0.826 21135113,12615916,23289756,16931761 Q8NHY2 P01100 RFWD2 FOS 0.49 25609649,26186194,26496610 Q8NHY2 P04637 RFWD2 TP53 0.939 21625211,15103385,16931761,23736031 Q92905 Q8NHY2 COPS5 RFWD2 0.236 19295130 Q8NHY2 P31946 RFWD2 YWHAB 0.454 21135113 Q92519 Q8NHY2 TRIB2 RFWD2 0.309 25311538 Q96L50 Q8NHY2 LRR1 RFWD2 0.236 19295130 Q96PM5 Q8NHY2 RCHY1 RFWD2 0.376 20333547 Q9BT78 Q8NHY2 COPS4 RFWD2 0.236 19295130 Q9BW61 Q8NHY2 DDA1 RFWD2 0.454 25117710,19295130 Q96RU7 Q8NHY2 TRIB3 RFWD2 0.569 26186194,21572435,25117710 Q96RU8 Q8NHY2 TRIB1 RFWD2 0.765 25117710,27041596 Q9UBW8 Q8NHY2 COPS7A RFWD2 0.236 19295130 Q9UNS2 Q8NHY2 COPS3 RFWD2 0.236 19295130 Q8NHY2 P17535 RFWD2 JUND 0.569 23289756,12615916 Q8NHY2 Q13618 RFWD2 CUL3 0.236 19295130 Q8NHY2 P18031 RFWD2 PTPN1 0.569 23439647 Q8NHY2 Q13620 RFWD2 CUL4B 0.236 17041588,19295130 Q8NHY2 Q14565 RFWD2 DMC1 0.126 26186194 Q8NHY2 Q14764 RFWD2 MVP 0.61 25117710,15994960 Q8NHY2 Q00987 RFWD2 MDM2 0.376 20333547 Q8NHY2 P50549 RFWD2 ETV1 0.659 20062082,26186194,21572435,25117710 Q8NHY2 P14921 RFWD2 ETS1 0.659 25117710 Q8NHY2 Q15717 RFWD2 ELAVL1 0.126 19322201 Q8NHY2 Q06124 RFWD2 PTPN11 0.21 23269672 Q8NHY2 A0A0F7REZ1 RFWD2 A0A0F7REZ1 0.126 20711500

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 MDM4 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database FOS RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database TP53 RFWD2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database JUN RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database REG1A RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database UBB RFWD2 MI:0362 inference MI:1106 pathways database UBC RFWD2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database HSPA8 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database ETS1 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database ETS2 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database FOSL2 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database HSPA6 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database JUNB RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database JUND RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database TCP1 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database PTPN1 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database ATF6 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database UBA1 RFWD2 MI:0362 inference MI:0461 interaction database YWHAB RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database SFN RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database CCT6A RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database ETV5 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database ETV4 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database CDKN1B RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database REG1B RFWD2 MI:0362 inference MI:0461 interaction database CCT5 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database FASN RFWD2 MI:0362 inference MI:0461 interaction database CCT3 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database ETV1 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database CCT8 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database CCT4 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D1 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database HSPA2 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database COPS2 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database WDR5 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database UBE2D2 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database RBX1 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database RPS27A RFWD2 MI:0362 inference MI:1106 pathways database UBA52 RFWD2 MI:0362 inference MI:1106 pathways database YWHAZ RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database SKP1 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database CCT2 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database MDM2 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database PTPN11 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database FOXO1 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database GPS1 RFWD2 MI:0362 inference MI:0461 interaction database ERCC8 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database ATM RFWD2 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database CUL1 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database CUL2 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database CUL3 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database CUL4A RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database CUL4B RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database DMC1 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database MVP RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database TCEB2 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database ELAVL1 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database DDB1 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database CRTC2 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database COPS6 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database DET1 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database STK40 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database ZNF397 RFWD2 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 RB1CC1 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 DCAF11 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 DDB2 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 TRIB2 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 COPS5 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 UBE2E3 MI:0362 inference MI:0461 interaction database RFWD2 SIPA1 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 LRR1 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 RCHY1 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 TRIB3 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 TRIB1 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 COPS8 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 CCT7 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 GRWD1 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 COPS4 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 DDA1 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 BTBD2 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 COPS7B MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 TM9SF3 MI:0362 inference MI:0461 interaction database RFWD2 KLHL42 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 COPS7A MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 PARP4 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 COPS3 MI:0045 experimental interaction detection MI:0461 interaction database RFWD2 NOSIP MI:0362 inference MI:0461 interaction database RFWD2 VPRBP MI:0045 experimental interaction detection MI:0461 interaction database