Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 1 223970745 rs1153942 T G rs1153942 2.74E-04 GEMCITABINE|CYTARABINE MANNOSYLTRANSFERASES|PIGB PROTEIN, HUMAN|RNA, SMALL INTERFERING|DEOXYCYTIDINE Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 C intron GWASdb_drug 1 223970745 rs1153942 T G rs1153942 2.74E-04 Response to cytidine analogues (gemcitabine) HPOID:0002664 DOID:162 C intron GWASdb_trait 1 224020068 rs41345146 G T rs41345146 3.07E-05 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs6698919 1 224015397 224015397 intronic 0.840321 0.0755547831065846 GWAS of prostate cancer rs1153942 1 223970745 223970745 intronic 0.042274 1.37392665693231

Disease associated variation - OMIM Ensembl_gene_ID Approved Gene Symbol MIM Number ENSG00000143514.16 TP53BP2 602143