PTM - CPLM Gene Name UniProt ID Type Position Code LYST; CHS; CHS1 Q99698 Acetylation 1703 K LYST; CHS; CHS1 Q99698 Acetylation 1710 K LYST; CHS; CHS1 Q99698 Ubiquitination 1305 K LYST; CHS; CHS1 Q99698 Ubiquitination 3191 K

PTM - dbPAF Gene Name UniProt ID Position Type Species LYST; CHS; CHS1 Q99698 1017 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 1061 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 1119 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 1194 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 1195 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 1489 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 1490 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 1491 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 1509 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 1510 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 161 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 164 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 166 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 193 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2103 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2105 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2111 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2122 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2124 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2128 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2138 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2139 Y Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2149 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2152 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2153 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2155 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2166 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2167 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2170 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2213 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2217 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2239 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2242 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2264 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2270 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2358 Y Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2612 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2627 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2632 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2676 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2707 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 2708 Y Homo sapiens(Human) LYST; CHS; CHS1 Q99698 316 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 3204 Y Homo sapiens(Human) LYST; CHS; CHS1 Q99698 3207 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 3208 Y Homo sapiens(Human) LYST; CHS; CHS1 Q99698 3210 Y Homo sapiens(Human) LYST; CHS; CHS1 Q99698 3215 Y Homo sapiens(Human) LYST; CHS; CHS1 Q99698 3299 Y Homo sapiens(Human) LYST; CHS; CHS1 Q99698 3457 Y Homo sapiens(Human) LYST; CHS; CHS1 Q99698 3659 S Homo sapiens(Human) LYST; CHS; CHS1 Q99698 3662 T Homo sapiens(Human) LYST; CHS; CHS1 Q99698 517 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q99698 K351-ac Acetylation MMPENLRkNLTELLR Q99698 K1622-ac Acetylation IWVSGQRkPDVTLDF Q99698 K1703-ac Acetylation VMPCKYGkPVNDYSk Q99698 K1710-ac Acetylation kPVNDYSkYINKEIL Q99698 K2731-ac Acetylation GSKQQWTkILWSCKE Q99698 K3749-ac Acetylation VREITFPkSNKPIIS Q99698 K979-m1 Methylation MLSSVFQkQFYRLGG Q99698 S154-p Phosphorylation RKITHRYsVRDARKt Q99698 T161-p Phosphorylation sVRDARKtQLstsDS Q99698 S164-p Phosphorylation DARKtQLstsDSEAN Q99698 T165-p Phosphorylation ARKtQLstsDSEANs Q99698 S166-p Phosphorylation RKtQLstsDSEANsD Q99698 S172-p Phosphorylation tsDSEANsDEKGIAM Q99698 T193-p Phosphorylation HLLHHFLtSFPKQDH Q99698 S263-p Phosphorylation DLCHVLLsLLEKVCK Q99698 T316-p Phosphorylation RVVSAGWtEEPVALI Q99698 S494-p Phosphorylation KSEQLHHsMCTRKRH Q99698 S517-p Phosphorylation MHHHRDLsGLLVSAF Q99698 S1054-p Phosphorylation PIPSELGsLKKSADs Q99698 S1061-p Phosphorylation sLKKSADsLGKLELQ Q99698 T1119-p Phosphorylation ICLHGARtSQQKMEL Q99698 S1194-p Phosphorylation HQSAEELssQPGDFS Q99698 S1195-p Phosphorylation QSAEELssQPGDFSE Q99698 S1225-p Phosphorylation EEGYEADsEsNPEDG Q99698 S1227-p Phosphorylation GYEADsEsNPEDGET Q99698 S1489-p Phosphorylation ECIHEAEsttEKGKK Q99698 T1490-p Phosphorylation CIHEAEsttEKGKKI Q99698 T1491-p Phosphorylation IHEAEsttEKGKKIK Q99698 S1503-p Phosphorylation KIKKRNKsLILPDss Q99698 S1509-p Phosphorylation KsLILPDssFDGTES Q99698 S1510-p Phosphorylation sLILPDssFDGTESD Q99698 T1982-p Phosphorylation EYKEGQLtPMPREVC Q99698 S2103-p Phosphorylation MAAHMLRsRsLPAFP Q99698 S2105-p Phosphorylation AHMLRsRsLPAFPtS Q99698 T2111-p Phosphorylation RsLPAFPtSSLLTQS Q99698 T2122-p Phosphorylation LTQSQKLtGsLGCsI Q99698 S2124-p Phosphorylation QSQKLtGsLGCsIDR Q99698 S2128-p Phosphorylation LtGsLGCsIDRLQNI Q99698 T2138-p Phosphorylation RLQNIADtyVAtQSK Q99698 Y2139-p Phosphorylation LQNIADtyVAtQSKK Q99698 T2142-p Phosphorylation IADtyVAtQSKKQNs Q99698 S2149-p Phosphorylation tQSKKQNsLGsSDtL Q99698 S2152-p Phosphorylation KKQNsLGsSDtLKKG Q99698 T2155-p Phosphorylation NsLGsSDtLKKGKED Q99698 S2166-p Phosphorylation GKEDAFIssCEsAKT Q99698 S2167-p Phosphorylation KEDAFIssCEsAKTV Q99698 S2170-p Phosphorylation AFIssCEsAKTVCEM Q99698 S2186-p Phosphorylation AVLSAQVsVSDVPKG Q99698 S2213-p Phosphorylation QLGAEPRsEDDsPGD Q99698 S2217-p Phosphorylation EPRsEDDsPGDESCP Q99698 S2235-p Phosphorylation DYLKGLAsFQRsHSt Q99698 S2239-p Phosphorylation GLAsFQRsHStIASL Q99698 T2242-p Phosphorylation sFQRsHStIASLGLA Q99698 S2264-p Phosphorylation AAVGRWPsLVDRNtD Q99698 T2270-p Phosphorylation PsLVDRNtDDWENFA Q99698 Y2358-p Phosphorylation VIKLLDAyFARASKE Q99698 S2591-p Phosphorylation AVVQKRKsIAGPRKF Q99698 S2612-p Phosphorylation SLLMKMRsVANDELH Q99698 S2627-p Phosphorylation VMMQRRMsQENPsQA Q99698 S2632-p Phosphorylation RMsQENPsQATETEL Q99698 S2676-p Phosphorylation TPENVTQsKTSVFQT Q99698 T2707-p Phosphorylation PFQKEIFtyLVEGFK Q99698 Y2708-p Phosphorylation FQKEIFtyLVEGFKV Q99698 S3022-p Phosphorylation RVNRRCIsVAPsRET Q99698 S3026-p Phosphorylation RCIsVAPsRETAGEL Q99698 Y3208-p Phosphorylation EDRYVDTyKyLEEEy Q99698 Y3210-p Phosphorylation RYVDTyKyLEEEyRK Q99698 Y3215-p Phosphorylation yKyLEEEyRKGARED Q99698 Y3299-p Phosphorylation ELIPEFFyLPEFLVN Q99698 Y3457-p Phosphorylation EQVKEITyPSPLSWI Q99698 S3659-p Phosphorylation QSLAGHKsPVtAVSA Q99698 T3662-p Phosphorylation AGHKsPVtAVSASET Q99698 K1305-ub Ubiquitination KIIRQKEkNVFLLMQ Q99698 K3191-ub Ubiquitination LIYRNLSkPIAVQYK

PTM - dbPTM UniProt ID Position Code Type Resources References Q99698 2103 S Phosphorylation Swiss-Prot 1010711 19369195 Q99698 2105 S Phosphorylation Swiss-Prot 1010711 19369195 Q99698 2124 S Phosphorylation Swiss-Prot 1010711 19369195 Q99698 2105 S Phosphorylation PhosphoELM.10011 18669648 Q99698 1305 K Ubiquitylation Phosphositeplus.1010730 21890473 Q99698 3191 K Ubiquitylation Phosphositeplus.1010730 21890473 Q99698 1703 K Acetylation Phosphositeplus.1010730 20167786 Q99698 1710 K Acetylation Phosphositeplus.1010730 20167786 Q99698 2105 S Phosphorylation Phosphositeplus.1010730 19369195;20058876 Q99698 2124 S Phosphorylation Phosphositeplus.1010730 19369195;20058876;21659604 Q99698 2122 T Phosphorylation Phosphositeplus.1010730 20058876 Q99698 3204 Y Phosphorylation Phosphositeplus.1010730 18083107 Q99698 2105 S Phosphorylation HPRD 9.0 18669648,20058876 Q99698 2124 S Phosphorylation HPRD 9.0 20058876 Q99698 2122 T Phosphorylation HPRD 9.0 20058876

PTM - HPRD Symbol Position Code Type References LYST 2105 S Phosphorylation 18669648,20058876 LYST 2122 T Phosphorylation 20058876 LYST 2124 S Phosphorylation 20058876

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q99698 2105 S 18669648 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q99698 2105 Phosphoserine 19369195;23186163 Q99698 2124 Phosphoserine 24275569

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 1130 107552 - K Ubiquitination 21139048 1130 107552 - K Ubiquitination 21890473

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID LYST Homo sapiens (Human) 1305; 3191 "1305,IIRQKEKNVFLLM; 3191,IYRNLSKPIAVQY" 1305:21890473; 3191:21890473 LYST Homo sapiens (Human) 1305; 3191 "1305,IIRQKEKNVFLLM; 3191,IYRNLSKPIAVQY" 1305:21890473; 3191:21890473 LYST Homo sapiens (Human) 1305 "1305,IIRQKEKNVFLLM" 1305:21890473 LYST Homo sapiens (Human) 1305 "1305,IIRQKEKNVFLLM" 1305:21890473