PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBXN4 TMEM216 26638075 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G IP6K1 UBXN4 26186194 biogrid exp GP GP G G GP GP G GP GP G GP G GP G G GP GP G GP G GP GP GP P GP G GP GP G UBXN4 DERL2 22119785 biogrid exp G GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TOM1L1 UBXN4 16169070 hprd,biogrid,i2d,mint,intact exp GP GP P P G GP GP GP GP GP GP G GP P GP GP G P GP GP GP P GP GP G PSMA6 UBXN4 19822669 biogrid exp P P P P P P P P P P P P P P P P P P P P UBXN4 UBQLN1 25416956,19822669 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DPP8 UBXN4 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G EVC2 UBXN4 26638075 biogrid,intact exp GP P P P P GP P P GP GP G P P GP GP P GP GP P P P GP P G UBXN4 BCL11A 26186194 biogrid exp GP G G G GP GP G G G G G G GP GP G G G G GP GP GP G TMEM17 UBXN4 26638075 biogrid,intact exp P GP G P GP G P P G GP P P G G P GP P GP G P GP GP P P P P GP ACTA2 UBXN4 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G VPS13C UBXN4 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP G GP GP G GP GP G UBXN4 VPS13A 26186194 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G ELAVL1 UBXN4 19322201 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G FBXO11 UBXN4 26186194 biogrid exp G G G G G GP G G G G G GP GP G G GP GP G G G GP G G G GP G G G G TMEM67 UBXN4 26638075 biogrid,intact exp P P P P GP P GP P GP P P P GP GP G P P P P P P P GP ZNF24 UBXN4 20195357 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TCTN3 UBXN4 26638075 biogrid,intact exp G GP G G G GP G GP GP G G G G G G GP GP G GP G GP GP G GP GP G GP G G UBXN4 TCTN2 26638075 biogrid,intact exp GP G G G GP GP G GP GP G G G GP G G GP GP G GP G GP G G G GP GP GP GP G UBXN4 SEL1L 18711132 biogrid exp GP GP G G G GP G G GP G GP G GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G UBE4A UBXN4 26186194,22119785 biogrid exp GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G CANX UBXN4 16968747 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBXN4 AMFR 16968747, 25402006, 23023127 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBXN4 DERL1 16968747, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G VCP UBXN4 18775313,16968747,25078495,19822669, 25402006, 23023127, 21836163 biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBXN4 NSFL1C 26344197, 25402006 biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBXN4 UBQLN2 25402006 ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G TNFRSF1A UBXN4 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CD3D UBXN4 25402006, 21836163 pred GP G G GP G GP G GP GP G GP G G G G G G G G GP G GP G G G AXIN1 UBXN4 23023127 pred GP GP G GP GP G P GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SMARCA5 UBXN4 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBXN4 UBL7 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G TWF1 UBXN4 25402006 pred GP GP G G G G G GP GP G GP GP G GP G GP G G GP G GP GP G G GP G GP GP G PRPF40A UBXN4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBTD2 UBXN4 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G UBXN4 UBXN6 25402006 pred GP P G G GP GP G P P G GP P P P G GP GP GP GP G P P GP GP GP P GP GP G UBXN4 THUMPD1 25402006 pred GP GP G G GP GP G GP GP G GP G G GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBXN4 ZNF335 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN4 USP7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G LUC7L3 UBXN4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SVIP UBXN4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G P GP GP GP GP GP GP GP G USP8 UBXN4 25402006 pred G GP G G GP GP G G GP G GP G GP G G GP GP G GP G GP GP G GP GP G GP GP G COPB1 UBXN4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SRSF11 UBXN4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HSPB1 UBXN4 23023127 pred GP GP G G GP G G GP GP G GP GP GP G G GP G GP GP G GP GP GP GP GP G GP GP G UBXN4 ASPSCR1 25402006 pred GP GP G P GP G GP P G GP GP GP GP G GP GP P GP G GP GP GP GP GP G GP GP UBE2D2 UBXN4 23023127 pred GP G G G GP GP G G GP G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP GP G UBXN4 21836163 pred UBXN4 UBQLN3 23023127 pred G G G G G G GP G UBXN4 RNF19A 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBXN4 UBXN10 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP GP GP GP G GP GP GP GP GP G GP GP G UBXN4 NUB1 23023127 pred GP GP G G GP G G GP GP G GP GP GP GP G GP G GP GP G GP GP G GP GP GP GP GP G UBXN4 HDAC6 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G UBXN4 HERPUD2 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G KTN1 UBXN4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CFTR UBXN4 25402006 pred P P GP P P GP P GP P GP GP P UBXN4 SENP7 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G P GP GP GP GP GP GP P UBXN4 TLK1 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G USO1 UBXN4 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G UBE4B UBXN4 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G STX16 UBXN4 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G DNAJB1 UBXN4 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G HIF1A UBXN4 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP G GP G GP GP GP GP G UBXN4 MARCH7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G UBXN4 AUP1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SEC61G UBXN4 21836163 pred G G G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP G GP G GP GP GP GP G FCHSD2 UBXN4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP P GP GP GP GP G G NFX1 UBXN4 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G FRMD3 UBXN4 23023127 pred GP GP G G G GP G GP G G GP GP GP G GP GP GP GP G GP GP G G GP GP GP GP G LATS1 UBXN4 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP G GP GP G STXBP3 UBXN4 25402006 pred G GP G G GP GP G G GP G GP G GP G G GP GP G GP G GP GP GP GP GP G GP GP G UBXN7 UBXN4 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RBM39 UBXN4 25402006 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBXN4 EIF2AK4 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G G GP GP GP G GP GP GP GP G GP GP GP G EIF2AK2 UBXN4 23023127 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP G GP G GP GP GP G GP G GP GP G UBXN4 ERP44 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G UBXN4 FAF2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G BET1 UBXN4 16082366 pred G G G G G GP G GP GP G GP GP GP G G GP GP G G G G G G G GP G GP G G UBXN4 BAIAP2 23023127 pred P P G G GP GP G GP P G GP GP GP GP P GP GP GP G GP GP P P P P GP GP G UBXN4 GGA3 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP GP GP GP GP GP G UBXN4 G6PC2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G HERPUD1 UBXN4 25402006, 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G INSIG1 UBXN4 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN4 PHKB 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN4 SMC3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G IFI16 UBXN4 23023127 pred G G G G GP GP G G GP G GP G G GP G G GP GP G G G G G G G GP G G G DNAJB6 UBXN4 23023127 pred GP GP G G G GP G G G G G GP GP G G G GP G G G G G G G G G GP G UBC UBXN4 23023127 pred ABI1 UBXN4 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBQLNL UBXN4 23023127 pred P P P P P P P P G P P P P GP EPS8 UBXN4 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G LYN UBXN4 23023127 pred GP G G G GP GP G G GP G G G GP GP G GP GP G GP G GP GP GP GP GP GP G G CTTN UBXN4 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G MIDN UBXN4 23023127 pred GP GP G G GP GP G GP GP G GP G G G G GP GP G G G GP GP GP GP GP G GP GP G G2E3 UBXN4 21836163 pred G G G G G GP G G GP G GP G G G G G GP G G G G G G G G G G EP300 UBXN4 23023127 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G RHOQ UBXN4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UFL1 UBXN4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP G GP GP G DNAJC3 UBXN4 23023127 pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G PTPN3 UBXN4 25402006 pred GP GP G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP P GP GP G UBXN2B UBXN4 23023127 pred G GP G G G G G G GP G GP G GP G G GP G GP G G G GP G G GP G GP GP G UBXN4 RNF6 25402006 pred G GP G G GP GP G G GP G GP G GP G G GP GP G G G GP G G G GP GP GP GP G UBXN4 KBTBD4 23023127 pred GP GP GP G P G GP P P G GP GP G GP G P GP GP G GP G P GP BIRC2 UBXN4 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP G GP GP GP GP GP GP G DNAJA1 UBXN4 23023127 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G DEK UBXN4 23023127 pred GP G G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBXN4 SETD2 23023127 pred GP GP G G G GP G G GP G GP G GP GP G GP GP GP GP G GP G G GP GP G GP GP G UBXN4 SCAF11 25402006 pred GP G G G G GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP GP GP GP GP G UBXN4 VCPIP1 25402006 pred G G G G G G G GP GP G GP GP G GP G GP G G P G GP G G GP GP G GP G SYVN1 UBXN4 25402006 pred G GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G UBXN8 UBXN4 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBXN4 MIB2 21836163 pred P P G GP G GP P G GP P P P P GP GP GP G GP GP GP GP GP P P P G UBXN4 SORBS1 23023127 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G UBE2J2 UBXN4 23023127 pred G G G G G G G GP GP G G G GP G G GP G G G G GP G G GP GP G G G G WDFY3 UBXN4 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G NPHP1 UBXN4 23023127 pred P P G P P GP P P P P P G GP G P P P G P P GP UBXN4 BCLAF1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O75674 Q92575 two hybrid 16169070 direct interaction X 2 Q9GZP9 Q92575 affinity chromatography technology 22119785 physical association X 2 Q92575 Q9UBV2-2 affinity chromatography technology 18711132 physical association X 2 A0A024R284 Q92575 two hybrid 19822669 direct interaction X 2 A0A024R284 Q92575 pull down 19822669 direct interaction X 2 A0A024R284 Q92575 affinity chromatography technology 19822669 physical association X 2 A0A024R284 Q92575 two hybrid 25416956 direct interaction X 2 P55072 Q92575 affinity chromatography technology 19822669 physical association X 2 P55072 Q92575 affinity chromatography technology 16968747 physical association X 2 P55072 Q92575 affinity chromatography technology 18775313 physical association X 2 Q14139 Q92575 affinity chromatography technology 22119785 physical association X 2 P27824 Q92575 biochemical 16968747 colocalization X 2 P27824 Q92575 affinity chromatography technology 16968747 physical association X 2 Q9UKV5 Q92575 affinity chromatography technology 16968747 physical association X 2 P0CG48 Q92575 affinity chromatography technology 24816145 physical association X 2 P0CG48 Q92575 affinity chromatography technology 21139048 physical association X 2 P0CG48 Q92575 affinity chromatography technology 21906983 physical association X 2 Q9BUN8-2 Q92575 affinity chromatography technology 16968747 physical association X 2 O75674 Q92575 two hybrid 16169070 - X 2 O75674 Q92575 two hybrid 16169070 - X 2 O75674 Q92575 two hybrid pooling approach 16169070 physical association X 2 Q92575 Q5NIJ3 two hybrid pooling approach 20711500 physical association X 2 A0A024R284 Q92575 two hybrid prey pooling approach 25416956 physical association X 2 A0A024R284 Q92575 two hybrid array 25416956 physical association X 2 A0A024R284 Q92575 validated two hybrid 25416956 physical association X 2 P55072 Q92575 anti tag coimmunoprecipitation 18775313 association X 2 P55072 Q92575 anti tag coimmunoprecipitation 18775313 physical association X 2 Q92575 Q5NEU6 two hybrid pooling approach 20711500 physical association X 2 P17028 Q92575 display technology 20195357 physical association X 2 A0A024R258 Q92575 two hybrid prey pooling approach 25416956 physical association X 2 A0A024R258 Q92575 two hybrid array 25416956 physical association X 2 A0A024R258 Q92575 validated two hybrid 25416956 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CANX UBXN4 MI:0401(biochemical)|MI:0401(biochemical) 16968747 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0403(colocalization) (biogrid)|(biogrid) BIOGRID_196027|BIOGRID_196026 prey|prey bait|bait TOM1L1 UBXN4 MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|MI:0468(hprd)|MI:0471(mint)|(intact)|(biogrid) MINT_34510|HPRD_29434|MINT_63466|UniProt_156664|BIOGRID_94089 prey|-|prey|prey|prey bait|-|bait|bait|bait ZNF24 UBXN4 MI:0034(display technology) 20195357 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_104603 bait prey UBXN4 DERL1 MI:0401(biochemical) 16968747 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_196030 bait prey ELAVL1 UBXN4 MI:0096(pull down) 19322201 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_187271 bait prey UBXN4 UBQLN1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 19822669 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_190308|BIOGRID_190307|BIOGRID_190311 prey|prey|bait bait|bait|prey UBXN4 AMFR MI:0401(biochemical) 16968747 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_196029 bait prey VCP UBXN4 MI:0401(biochemical)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 16968747,18775313,19822669 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(biogrid) BIOGRID_196028|UniProt_97380|UniProt_183189|UniProt_97391|UniProt_168926|UniProt_183200|BIOGRID_148724|BIOGRID_190310 prey|prey|prey|prey|prey|prey|prey|prey bait|bait|bait|bait|bait|bait|bait|bait UBC UBXN4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21139048,21906983 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_177920|BIOGRID_168547 bait|bait prey|prey UBXN4 SEL1L MI:0004(affinity chromatography technology) 18711132 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_193752 prey bait

PPI - HINT Gene A Gene B PMID Method Quality VCP UBXN4 16968747,19822669,18775313,18775313 0004,0004,0004,0007 LC ACTA2 UBXN4 26186194 0004 HT UBE4A UBXN4 22119785,26186194,26389662 0004,0004,0004 LC,HT TMEM67 UBXN4 26638075,26638075 1314,1313 HT TCTN3 UBXN4 26638075,26638075 1314,1313 HT DPP8 UBXN4 26186194 0004 HT VPS13C UBXN4 26186194,26389662 0004,0004 HT,LC EVC2 UBXN4 26638075,26638075 1314,1313 HT TMEM17 UBXN4 26638075,26638075 1314,1313 HT FBXO11 UBXN4 26186194 0004 HT IP6K1 UBXN4 26186194,26389662 0004,0004 HT,LC UBXN4 TCTN2 26638075,26638075 1314,1313 HT UBXN4 VPS13A 26186194,26389662 0004,0004 HT,LC UBXN4 BCL11A 26186194 0004 HT UBXN4 TMEM216 26638075,26638075 1314,1313 HT UBXN4 NSFL1C 26344197 0401 HT UBXN4 HEL-S-70 26389662,19822669,18775313,16968747 0004,0004,0004,0004 LC ACTA2 UBXN4 26186194 0004 HT UBE4A UBXN4 26186194 0004 HT TMEM67 UBXN4 26638075,26638075 1314,1313 HT TCTN3 UBXN4 26638075,26638075 1314,1313 HT DPP8 UBXN4 26186194 0004 HT VPS13C UBXN4 26186194 0004 HT EVC2 UBXN4 26638075,26638075 1314,1313 HT TMEM17 UBXN4 26638075,26638075 1314,1313 HT FBXO11 UBXN4 26186194 0004 HT IP6K1 UBXN4 26186194 0004 HT UBXN4 TCTN2 26638075,26638075 1314,1313 HT UBXN4 VPS13A 26186194 0004 HT UBXN4 BCL11A 26186194 0004 HT UBXN4 TMEM216 26638075,26638075 1314,1313 HT UBXN4 NSFL1C 26344197 0401 HT VCP UBXN4 16968747,19822669,18775313,18775313 0004,0004,0004,0007 LC UBE4A UBXN4 22119785,26389662 0004,0004 LC VPS13C UBXN4 26389662 0004 LC IP6K1 UBXN4 26389662 0004 LC UBXN4 VPS13A 26389662 0004 LC UBXN4 HEL-S-70 26389662,19822669,18775313,16968747 0004,0004,0004,0004 LC TOM1L1 UBXN4 16169070,16169070 0018,0398 HT ZNF24 UBXN4 20195357 0034 LC CANX UBXN4 16968747,16968747 0401,0004 LC UBXN4 UBQLN1 19822669,25416956,25416956,19822669,25416956,25416956,19822669 0018,0397,1112,0004,0018,1356,0096 LC,HT UBXN4 NSFL1C 26344197 0401 LC UBXN4 HEL-S-70 25078495 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q92575 P17028 UBXN4 ZNF24 0.126 20195357 Q9GZP9 Q92575 DERL2 UBXN4 0.126 22119785 Q9P0N5 Q92575 TMEM216 UBXN4 0.236 26638075 Q92575 Q709C8 UBXN4 VPS13C 0.236 26389662,26186194 Q92575 Q92551 UBXN4 IP6K1 0.236 26389662,26186194 Q96RL7 Q92575 VPS13A UBXN4 0.236 26389662,26186194 Q92575 P27824 UBXN4 CANX 0.309 16968747 Q96GX1 Q92575 TCTN2 UBXN4 0.236 26638075 Q92575 Q5HYA8 UBXN4 TMEM67 0.236 26638075 Q92575 Q6NUS6 UBXN4 TCTN3 0.236 26638075 Q92575 Q86UK5 UBXN4 EVC2 0.236 26638075 Q92575 Q86X19 UBXN4 TMEM17 0.236 26638075 Q92575 P55072 UBXN4 VCP 0.801 19822669,25078495,16968747,18775313,26389662 Q9UMX0 Q92575 UBQLN1 UBXN4 0.905 25416956,19822669,unassigned1304 Q9BZV1 Q92575 UBXN6 UBXN4 0.126 26389662 Q9BUN8 Q92575 DERL1 UBXN4 0.21 16968747 Q9UKV5 Q92575 AMFR UBXN4 0.21 16968747 Q9H165 Q92575 BCL11A UBXN4 0.126 26186194 Q92575 Q86XK2 UBXN4 FBXO11 0.126 26186194 Q92575 Q5NIJ3 UBXN4 SDHA 0.126 20711500 Q92575 Q5SWX8 UBXN4 ODR4 0.126 26389662 Q92575 Q6V1X1 UBXN4 DPP8 0.126 26186194 Q92575 Q6P1M0 UBXN4 SLC27A4 0.126 26389662 Q92575 Q5NEU6 UBXN4 DNAJ2 0.126 20711500 Q92575 Q15435 UBXN4 PPP1R7 0.126 26389662 Q92575 P62736 UBXN4 ACTA2 0.126 26186194 Q92575 P60900 UBXN4 PSMA6 0.21 19822669 Q92575 O75674 UBXN4 TOM1L1 0.286 16169070 Q9UBV2 Q92575 SEL1L UBXN4 0.21 18711132 Q9UNZ2 Q92575 NSFL1C UBXN4 0.081 26344197 Q92575 Q14139 UBXN4 UBE4A 0.416 22119785,26186194,26389662 Q92575 Q15717 UBXN4 ELAVL1 0.126 19322201

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 TOM1L1 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database UBC UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database ZNF24 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database CANX UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database VCP UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database PSMA6 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database ACTA2 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database UBE4A UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database PPP1R7 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database ELAVL1 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database TMEM67 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database ODR4 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database TCTN3 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database SLC27A4 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database DPP8 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database VPS13C UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database EVC2 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database TMEM17 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database FBXO11 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database IP6K1 UBXN4 MI:0045 experimental interaction detection MI:0461 interaction database UBXN4 TCTN2 MI:0045 experimental interaction detection MI:0461 interaction database UBXN4 VPS13A MI:0045 experimental interaction detection MI:0461 interaction database UBXN4 DERL1 MI:0045 experimental interaction detection MI:0461 interaction database UBXN4 UBXN6 MI:0045 experimental interaction detection MI:0461 interaction database UBXN4 DERL2 MI:0045 experimental interaction detection MI:0461 interaction database UBXN4 BCL11A MI:0045 experimental interaction detection MI:0461 interaction database UBXN4 TMEM216 MI:0045 experimental interaction detection MI:0461 interaction database UBXN4 SEL1L MI:0045 experimental interaction detection MI:0461 interaction database UBXN4 AMFR MI:0045 experimental interaction detection MI:0461 interaction database UBXN4 UBQLN1 MI:0045 experimental interaction detection MI:0461 interaction database