PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus PLSCR1 ATG12 16189514 hprd,biogrid,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ATG12 SERBP1 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 OTUD4 17353931 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 EPB41L5 17353931 intact exp G GP G G GP GP G G G G GP GP G G G GP GP G GP G GP G G G GP P GP GP G ATG12 DDX6 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 MOV10 17353931 intact exp G G G G G G G G G G G G G G G G G G G G G G ATG12 SF3A1 17353931 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 HTT 20417604 intact exp GP GP G G GP GP G G GP G P GP P GP G GP GP GP P G GP GP GP G GP GP GP GP ATG12 MRPL23 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G ATG12 CCDC59 17353931 intact exp GP GP G G GP GP G GP GP G GP G GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G ATG12 EIF3A 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 CAV1 24727585 biogrid exp GP G G G G GP G GP GP G GP GP GP G G G GP GP G G GP GP G G G G G G G ATG12 BCL2 22152474 biogrid exp G G G G GP GP G G GP G GP G G GP G G GP GP G G GP GP G G G GP G G G ATG12 RPL36 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G SF3B1 ATG12 17353931 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 DHX36 17353931 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 EXOC4 21241894 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G ATG12 APP 21832049 biogrid exp G GP G G GP GP G G GP G G G G G G GP GP G GP G GP GP G G GP G G GP G ATG12 ATG12 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 PTK2 16189514 hprd,biogrid,mint exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 SUN2 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 MRPS23 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 KRTAP4-12 16189514 hprd,biogrid,mint,intact exp ATG12 EIF3E 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G ATG12 KRT31 17353931 intact exp G G G GP G P P P G P GP G P P GP G GP P G ATG12 CHTOP 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 LMNB1 17353931 intact exp GP P G GP P P GP P P GP GP G GP P GP GP GP P P P GP GP GP P ATG12 MAP1B 20562859 biogrid,intact exp G GP G G G GP G G GP G GP G G G G G GP G GP G GP GP G G G G G GP G ATG12 KRT82 17353931 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G ATG12 MCL1 22152474 biogrid exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 EPRS 17353931 intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 EBLN2 17353931 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G ATG12 ATG4B 20562859 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 CDC37 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 SNRPB2 17353931 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ATG12 RALB 21241894 intact exp GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP G G GP GP GP GP G ATG12 MDFI 16189514 hprd,biogrid,mint,intact exp G G G P G P P G G P G GP P G G G P GP P G ATG12 RNMTL1 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 HNRNPAB 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 WIPI2 24954904 biogrid exp G GP G G G GP G G GP G GP G G G G G GP GP GP G GP GP GP GP G G GP GP G ATG12 DOCK9 23414517 intact exp GP GP G P GP G GP GP G GP GP GP GP G GP GP G P G GP GP GP GP GP GP GP GP G ATG12 TGM3 17353931 intact exp G G G G GP G G G G GP G G G GP GP G G GP G G G GP G CLASP2 ATG12 17353931 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G CRX ATG12 25416956 biogrid,intact exp P P P P P P P P P P P P P P P P P P P P P P ATG12 HNRNPA0 17353931 intact exp GP G G G G GP G G GP G GP G GP G G GP GP G GP G GP GP G GP GP G GP GP G ATG12 AUP1 17353931 biogrid,intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 HNRNPA3 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 RPS29 17353931 intact exp GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G POP7 ATG12 17353931 intact exp GP GP G G G GP G G GP G GP G GP G G G GP G GP G GP G G GP G G GP GP G ATG12 HNRNPUL1 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 HIST1H2BC, HIST1H2BE, HIST1H2BF, HIST1H2BG, HIST1H2BI 17353931 intact exp GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 FADD 15778222, 25402006 biogrid exp, ortho, pred GP GP G G G GP G GP GP G GP G GP GP G GP GP G GP G GP G GP GP GP GP GP GP G ATG12 ATG7 20562859,12482611,11096062,11890701, 25402006, 21836163, 16082366 innatedb,hprd,biogrid,intact exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 ATG10 12482611,16963840,26186194,17353931, 25402006, 21836163 innatedb,hprd,biogrid,intact exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP P GP GP GP G GP GP GP GP GP P P P G ATG12 ATG3 12207896,23202584,24186333,20562859,20723759,11825910,17353931, 25402006, 21836163, 16082366 innatedb,hprd,biogrid,intact,dip exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP GP GP GP G ATG12 ATG5 22342342,12207896,23202584,12890687,20562859,12482611,11825910,17353931, 25402006, 21836163, 16082366 innatedb,hprd,biogrid,intact exp, ortho, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 ATG16L1 20562859,20639872,17353931, 25402006, 21836163 innatedb,biogrid,intact exp, ortho, pred GP G GP GP G G GP GP G G G GP G G G G G GP G G G ATG12 BECN1 20562859, 21836163 intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 IFIH1 17709747, 25402006 innatedb,dip exp, pred GP GP P P G GP GP GP GP GP G GP P G P G GP GP GP P GP GP GP P ATG12 WDFY3 20417604, 21836163 innatedb,biogrid exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 WIPI1 23088497, 21836163 intact exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 TECPR1 22342342,20562859,21575909, 25402006 innatedb,biogrid,intact exp, pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP GP GP G GP GP G ATG12 MAVS 17709747, 25402006 innatedb,dip exp, pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 DDX58 17709747, 25402006 innatedb,dip exp, pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G ATG12 GABARAP 20562859, 25402006 biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G XPO1 ATG12 26673895, 16082366 biogrid exp, pred GP GP G G GP GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 RB1CC1 17353931, 25402006 intact exp, pred G GP G G G GP G G GP G GP G GP G G GP GP GP GP G GP GP GP G GP G GP GP G ATG12 RAB33B ortho G GP G G GP G G GP GP G G G G G G G G G G G G G GP G G G GP GP G ATG12 PSMC4 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 GABARAPL1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G G G GP G GP GP GP G GP GP G ATG12 ATG14 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 MFN1 25402006 pred G GP G G G GP G G GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP G GP GP G ATG12 ATG16L2 25402006 pred GP G G G G GP G GP GP G GP G G G G G GP G P G GP G G G G G GP GP G ATG12 GART 16082366 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 TRIM25 25402006 pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G ATG12 FNBP1L 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G ATG12 GABARAPL2 25402006 pred G GP G G GP GP G GP GP G GP G G G G GP GP G GP G G GP GP G GP G GP GP G ATG12 DHX58 25402006 pred P P P P P P P P P P P P P P ATG12 SPNS1 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G P G GP GP G G GP GP GP GP G ATG12 EIF2S3 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G ATG12 AIMP1 25402006, 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 NXF1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 UBA7 25402006 pred P P P P P P P P P P P P P P P P P P ATG12 PSMA3 25402006 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP G GP G GP GP GP G GP G GP GP G ATG12 MMS19 16082366 pred GP GP G G G GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 UVRAG 21836163 pred G G G G G GP G GP G G GP G GP G G G GP G G G GP G G G G G GP GP G ATG12 PPTC7 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G ATG12 RAB7A 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG13 ATG12 25402006 pred GP G G G G GP G GP GP G GP G GP G G GP GP G GP G GP G G G GP GP GP GP G ATG12 MAP1LC3A 25402006, 21836163 pred G GP G G G GP G G GP G G GP G G G GP GP G GP G G G G G GP G G GP G ATG12 NAP1L1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 RGS19 21836163, 16082366 pred GP GP G G GP GP G G GP G GP GP GP GP G G GP G GP G GP GP GP GP G GP GP GP G ATG12 TP53 25402006 pred G G G G G G G G G G G G G G G GP G G G G GP G G G GP G G GP G HRK ATG12 21836163 pred P P G P GP P P P P P GP P P G P P P P P P BNIP3L ATG12 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G CFLAR ATG12 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 REXO2 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 PSMA2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G ATG12 HSPE1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 OAT 16082366 pred GP GP G G GP GP G GP G G GP GP GP G G GP GP G GP G G G GP GP GP G GP GP G ATG12 PRMT2 25402006 pred G GP G G GP GP G GP GP G GP G G GP G GP GP GP GP G GP GP GP GP GP G GP GP G PSMD3 ATG12 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 ATG9A 21836163 pred G GP G G G GP G GP GP G GP G G G G GP GP G GP G G G GP G GP G GP GP G ATG12 NUP98 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G ATG12 NSF 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 EEF1D 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 CYLD 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP ATG12 RAB33A 21836163 pred P G G GP GP G G P G P GP GP P GP G GP G G G P P P GP G ATG12 TMEM173 25402006 pred GP G G G GP GP G GP GP G G G GP GP G G GP G GP G GP GP GP G G GP GP GP G ATG12 TRAF6 25402006 pred GP GP G G GP G G GP GP G GP GP GP G G GP G GP G G GP GP GP G GP GP GP GP G ATG12 AZI2 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 PCSK9 16082366 pred G G G G G G GP P G P G G G ATG12 CLTC 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G ATG12 MAP1LC3B 25402006 pred G GP G G GP GP G GP GP G GP G G G G GP GP G G G G G G GP GP G GP GP G ATG12 PSMC2 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 MAP1LC3C 25402006, 21836163 pred G G G ATG12 ATG101 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP GP G ATG12 RNF125 25402006 pred GP GP G G GP GP G G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP P G ATG12 PSMD2 16082366 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP GP GP GP GP GP G PSMD14 ATG12 16082366 pred GP GP G G GP GP G GP GP G GP GP GP G G GP GP GP GP G GP G G GP GP G GP GP G ATG12 TP63 25402006 pred GP G G G G G G G G G G G G G G G G G G GP GP G G G G G UBE2L6 ATG12 25402006 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G ATG12 PSMD4 16082366 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G ATG12 BRD7 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G ATG12 HPRT1 25402006 pred GP GP G G G GP G G GP G GP GP GP GP G GP GP G GP G GP GP GP G GP GP GP GP G ATG12 VMP1 21836163 pred GP GP G GP P G GP GP GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G PRPF40A ATG12 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G ATG12 RNF135 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP G GP GP G ATG12 IKBKE 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DDX3X ATG12 25402006 pred G GP G G GP GP G G GP G G G GP GP G GP GP G GP G GP GP GP G GP GP GP GP G ATG12 RAB9A 21836163 pred GP GP G G GP GP G G GP G GP GP GP GP G GP GP GP GP G GP GP GP G GP GP GP GP G ATG12 NUP62 21836163 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP P G GP GP GP GP GP GP GP GP G ATG12 FGFR1 25402006 pred GP GP G G GP GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q13158 O94817 affinity chromatography technology 15778222 physical association X 2 O94817 Q9NT62 affinity chromatography technology 20723759 physical association X 2 O94817 Q9CPX6 affinity chromatography technology 20723759 physical association X 2 O94817 A9UGY9 affinity chromatography technology 22342342 physical association X 2 O94817 Q07820 affinity chromatography technology 22152474 physical association X 2 O94817 A9UGY9 x-ray crystallography 23202584 association X 2 O94817 Q9CPX6 affinity chromatography technology 23202584 physical association X 2 O94817 A9UGY9 affinity chromatography technology 12890687 physical association X 2 O94817 Q7Z4F3 affinity chromatography technology 24727585 physical association X 2 O94817 Q7Z4F3 affinity chromatography technology 24727585 physical association X 2 O94817 Q9NT62 pull down 24186333 direct interaction X 2 O94817 Q6NX51 affinity chromatography technology 21241894 physical association X 2 O94817 A9UGY9 affinity chromatography technology 17353931 physical association X 2 O94817 Q9NT62 affinity chromatography technology 11825910 physical association X 2 O94817 Q9Y4P1 affinity chromatography technology 20562859 physical association X 2 O94817 A9UGY9 affinity chromatography technology 20562859 physical association X 2 O94817 Q9NT62 affinity chromatography technology 20562859 physical association X 2 O94817 Q9NT62 affinity chromatography technology 20562859 physical association X 2 O94817 A9UGY9 affinity chromatography technology 20562859 physical association X 2 O94817 Q9BQ66 two hybrid 16189514 direct interaction X 2 O94817 two hybrid 16189514 direct interaction X 2 O94817 A0A024RCY2 two hybrid 16189514 direct interaction X 2 P0CG48 O94817 affinity chromatography technology 21139048 physical association X 2 P0CG48 O94817 affinity chromatography technology 21906983 physical association X 2 Q9Y679-2 O94817 affinity chromatography technology 17353931 physical association X 2 O94817 Q7Z6L1 affinity chromatography technology 22342342 physical association X 2 O94817 A0A024R2B3 affinity chromatography technology 22152474 physical association X 2 O94817 A0A024RDI0 affinity chromatography technology 20417604 physical association X 2 O94817 P05067-7 pull down 21832049 direct interaction X 2 O94817 E7EVC7 x-ray crystallography 23202584 association X 2 O94817 Q8R1P4 affinity chromatography technology 12890687 physical association X 2 O94817 affinity chromatography technology 24954904 physical association X 2 O94817 O43186 two hybrid 25416956 direct interaction X 2 O94817 Q9H2U1-2 affinity chromatography technology 17353931 physical association X 2 O94817 Q01804 affinity chromatography technology 17353931 physical association X 2 O94817 A0A024R1K8 affinity chromatography technology 17353931 physical association X 2 O94817 E7EVC7 affinity chromatography technology 17353931 physical association X 2 O94817 Q7Z497 affinity chromatography technology 17353931 physical association X 2 O94817 Q7Z6L1 affinity chromatography technology 20562859 physical association X 2 O94817 E7EVC7 affinity chromatography technology 20562859 physical association X 2 O94817 P46821 affinity chromatography technology 20562859 physical association X 2 O94817 O95352 affinity chromatography technology 20562859 physical association X 2 O94817 Q7Z6L1 affinity chromatography technology 20562859 physical association X 2 O94817 O95352 two hybrid 11096062 direct interaction X 2 O94817 O15162 two hybrid 16189514 direct interaction X 2 O95166 O94817 affinity chromatography technology 20562859 physical association X 2 Q9H0Y0 O94817 affinity chromatography technology 17353931 physical association X 2 O94817 anti tag coimmunoprecipitation 17709747 - C 3 O94817 anti tag coimmunoprecipitation 17709747 - C 3 O94817 O95786 anti tag coimmunoprecipitation 17709747 physical association X 2 O94817 O95786 anti tag coimmunoprecipitation 17709747 physical association X 2 O94817 Q9NT62 isothermal titration calorimetry 23202584 direct interaction X 2 O94817 Q9CPX6 anti tag coimmunoprecipitation 23202584 physical association X 2 O94817 anti tag coimmunoprecipitation 17709747 - C 3 O94817 anti tag coimmunoprecipitation 17709747 - C 4 O94817 Q9BYX4 anti tag coimmunoprecipitation 17709747 physical association X 2 Q7Z434 O94817 anti tag coimmunoprecipitation 17709747 physical association X 2 Q05397 O94817 two hybrid 16189514 - X 2 Q05397 O94817 two hybrid 16189514 - X 2 O94817 in vivo 12665549 - C 3 O94817 in vivo 12665549 - C 3 O94817 in vivo 12665549 - C 3 O94817 A0A024RCY2 two hybrid 16189514 - X 2 O94817 Q9NT62 in vivo 11825910 - X 2 O94817 A0A024RCY2 two hybrid 16189514 - X 2 O94817 Q9BQ66 two hybrid 16189514 - X 2 O94817 A9UGY9 in vitro 11825910,12482611 - X 2 O94817 A9UGY9 in vivo 11825910,12482611 - X 2 O94817 Q9NT62 in vivo 11825910 - X 2 O94817 Q9BQ66 two hybrid 16189514 - X 2 O94817 A9UGY9 in vitro 11825910,12482611 - X 2 O94817 A9UGY9 in vivo 11825910,12482611 - X 2 O95352-3 O94817 in vivo 11890701,12482611 - X 2 O95352-3 O94817 two hybrid 11890701,12482611 - X 2 O95352-3 O94817 in vivo 11890701,12482611 - X 2 O95352-3 O94817 two hybrid 11890701,12482611 - X 2 O94817 two hybrid 16189514 - X 2 O94817 two hybrid 16189514 - X 2 Q9H0Y0 O94817 in vitro 12482611 - X 2 Q9H0Y0 O94817 in vivo 12482611 - X 2 Q9H0Y0 O94817 in vitro 12482611 - X 2 Q9H0Y0 O94817 in vivo 12482611 - X 2 O94817 anti bait coimmunoprecipitation 21241894 association C 3 O94817 anti tag coimmunoprecipitation 20417604 association C 3 O94817 anti bait coimmunoprecipitation 21241894 association C 5 Q9BUJ2 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 anti tag coimmunoprecipitation 20562859 association C 12 O94817 anti tag coimmunoprecipitation 20562859 physical association C 9 O94817 anti tag coimmunoprecipitation 20562859 physical association C 11 A0A024RCB2 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9HCM4 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q9BQ66 two hybrid pooling approach 16189514 physical association X 2 O94817 A0A024RCY2 two hybrid pooling approach 16189514 physical association X 2 O94817 Q9NT62 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 A9UGY9 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 P60228 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 A0A024R7B7 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q9P031 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 A0A024R1P7 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q9Y3U8 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q9HCE1 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q6P2I7 anti bait coimmunoprecipitation 17353931 physical association X 2 Q8TDY2 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 Q08188 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 P08579 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 P07814 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 Q99729 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 anti tag coimmunoprecipitation 20562859 physical association C 6 O94817 anti tag coimmunoprecipitation 20562859 physical association C 12 Q9NSB4 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 O75817 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 Q5MNZ9 O94817 confocal microscopy 23088497 colocalization X 2 O94817 O15162 two hybrid pooling approach 16189514 physical association X 2 O94817 Q676U5 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q9HC36 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q9Y3Y2 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q9Y679 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q13151 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 A0A024R1K8 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 P51991 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q15323 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q96F87 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q01804 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 P26196 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 P20700 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 Q8NC51 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 P62273 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 O43186 two hybrid prey pooling approach 25416956 physical association X 2 O94817 O43186 two hybrid array 25416956 physical association X 2 O94817 O43186 validated two hybrid 25416956 physical association X 2 Q9Y3D9 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9H0Y0 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9H2U1 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 B2R4S9 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 O75533 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 Q14152 O94817 anti bait coimmunoprecipitation 17353931 physical association X 2 Q9BZ29 O94817 two hybrid fragment pooling approach 23414517 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B ATG12 DKFZp666O0110 MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_67369|MINT_38186 prey|prey bait|bait ATG12 TGM3 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149716 bait prey ATG12 EPRS MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_150957 bait prey ATG12 RPL36 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149169 bait prey ATG12 CHTOP MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_146475 bait prey ATG12 MRPS23 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_148945 bait prey ATG12 ATG4B MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124992|UniProt_106953 bait|bait prey|prey ATG12 AUP1 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_146576|BIOGRID_83115 bait|bait prey|prey ATG12 EPB41L5 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_146549 bait prey ATG12 MOV10 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_148770 bait prey ATG12 RNMTL1 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_146433 bait prey ATG12 LMNB1 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149218 bait prey ATG12 WDFY3 MI:0004(affinity chromatography technology) 20417604 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_227464 prey bait ATG12 SNRPB2 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149325 bait prey ATG12 ATG5 MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo) 12482611,12665549,12890687,17353931,17709747,20562859,22342342,23202584 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|-|-|-|MI:0915(physical association)|- (biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|MI:0465(dip)|MI:0465(dip)|MI:0465(dip)|MI:0465(dip)|(intact)|MI:0468(hprd) BIOGRID_125041|HPRD_14831|BIOGRID_258535|BIOGRID_309445|UniProt_147166|BIOGRID_124995|BIOGRID_208006|BIOGRID_82070|DIP_54560|DIP_54559|DIP_54557|DIP_54561|UniProt_106953|HPRD_39258 prey|-|bait|bait|bait|bait|prey|bait|-|-|-|-|bait|- bait|-|prey|prey|prey|prey|bait|prey|-|-|-|-|prey|- ATG12 ATG10 MI:0493(in vivo)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology) 12482611,17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(intact)|(biogrid) HPRD_14832|UniProt_146595|BIOGRID_82579 -|bait|bait -|prey|prey ATG12 DHX36 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_146674|BIOGRID_81764 bait|bait prey|prey ATG12 CCDC59 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_150073 bait prey ATG12 HNRNPA3 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149552 bait prey ATG12 GABARAP MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124998|UniProt_106953 bait|bait prey|prey ATG12 DDX58 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 17709747 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|- MI:0465(dip)|MI:0465(dip)|MI:0465(dip) DIP_54579|DIP_54557|DIP_54561 -|-|- -|-|- ATG12 ATG7 MI:0493(in vivo)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 11096062,12482611,20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(biogrid)|(intact) HPRD_14830|BIOGRID_137898|BIOGRID_124996|UniProt_106953 -|prey|bait|bait -|bait|prey|prey ATG12 EBLN2 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_151017 bait prey ATG12 APP MI:0096(pull down) 21832049 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_228804 bait prey ATG12 OTUD4 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_150202|BIOGRID_81999 bait|bait prey|prey SF3B1 ATG12 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_151100|BIOGRID_83710 prey|prey bait|bait ATG12 MAVS MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 17709747 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|- MI:0465(dip)|MI:0465(dip)|MI:0465(dip) DIP_54560|DIP_54582|DIP_54561 -|-|- -|-|- ATG12 CAV1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 24727585 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_310098|BIOGRID_310100 prey|bait bait|prey ATG12 RPS29 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_151024 bait prey POP7 ATG12 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_146513 prey bait ATG12 HIST1H2BC MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149391 bait prey ATG12 DDX6 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_148754 bait prey ATG12 SF3A1 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid) UniProt_149492|BIOGRID_83116 bait|bait prey|prey ATG12 KRT31 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149636 bait prey ATG12 MAP1B MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 20562859 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_124994|UniProt_106953 bait|bait prey|prey ATG12 HNRNPUL1 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_148931 bait prey ATG12 SERBP1 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_150964 bait prey ATG12 DOCK9 MI:0663(confocal microscopy) 23414517 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_126957 prey bait ATG12 IFIH1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 17709747 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0465(dip)|MI:0465(dip) DIP_54559|DIP_54581 -|- -|- ATG12 MDFI MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0468(hprd) BIOGRID_80354|UniProt_153196|MINT_68140|MINT_38897|HPRD_22946 prey|unspecified role|prey|prey|- bait|unspecified role|bait|bait|- ATG12 HNRNPAB MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149695 bait prey ATG12 HDAC6 MI:0004(affinity chromatography technology) 22318606 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0796(suppressive genetic interaction defined by inequality) (biogrid) BIOGRID_192986 prey bait ATG12 CDC37 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149775 bait prey ATG12 MRPL23 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149948 bait prey ATG12 ATG16L1 MI:0004(affinity chromatography technology)|MI:0114(x-ray crystallography)|MI:0004(affinity chromatography technology)|MI:0006(anti bait coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo) 12665549,17353931,20562859,23202584 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(biogrid)|(biogrid)|(intact)|(intact)|MI:0468(hprd) BIOGRID_83176|BIOGRID_258534|BIOGRID_124993|UniProt_147130|UniProt_106953|HPRD_39258 bait|bait|bait|bait|bait|- prey|prey|prey|prey|prey|- ATG12 KRTAP4-12 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|MI:0471(mint)|MI:0468(hprd)|(intact)|(biogrid) MINT_38032|MINT_67215|HPRD_23185|UniProt_152641|BIOGRID_79797 bait|bait|-|unspecified role|bait prey|prey|-|unspecified role|prey ATG12 SUN2 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_150102 bait prey ATG12 TECPR1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 20562859,22342342 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(intact)|(intact) BIOGRID_124991|BIOGRID_125645|BIOGRID_208008|UniProt_106945|UniProt_106953 bait|prey|prey|prey|bait prey|bait|bait|prey|prey ATG12 RB1CC1 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_150621 bait prey ATG12 PTK2 MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_79956|HPRD_21556 prey|- bait|- ATG12 KRT82 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_151127 bait prey ATG12 ATG3 MI:0007(anti tag coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 11825910,17353931,20562859,20723759,24186333 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid)|(biogrid)|(intact) UniProt_106894|UniProt_147127|BIOGRID_125016|BIOGRID_201093|BIOGRID_110358|HPRD_14828|BIOGRID_310407|BIOGRID_124997|UniProt_106953 prey|bait|prey|bait|prey|-|prey|bait|bait bait|prey|bait|prey|bait|-|bait|prey|prey ATG12 EIF3E MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149689 bait prey ATG12 WIPI1 MI:0663(confocal microscopy) 23088497 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (intact) UniProt_124296 neutral component neutral component ATG12 UBC MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21139048,21906983 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_180881|BIOGRID_171712 prey|prey bait|bait ATG12 HNRNPA0 MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149357 bait prey ATG12 uniprotkb:(gene name) MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149728 bait prey PLSCR1 ATG12 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0018(two hybrid)|MI:0018(two hybrid) 16189514 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(intact)|MI:0471(mint)|MI:0471(mint) HPRD_23184|BIOGRID_79551|UniProt_152395|MINT_66974|MINT_37792 -|bait|unspecified role|bait|bait -|prey|unspecified role|prey|prey ATG12 BCL2 MI:0004(affinity chromatography technology) 22152474 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_208737 bait prey ATG12 EIF3A MI:0006(anti bait coimmunoprecipitation) 17353931 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_149392 bait prey ATG12 MCL1 MI:0004(affinity chromatography technology) 22152474 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_208736 bait prey

PPI - HINT Gene A Gene B PMID Method Quality SF3B1 ATG12 17353931,17353931 0006,0004 HT POP7 ATG12 17353931 0006 HT ATG12 ATG7 20562859,20562859 0007,0004 HT ATG12 EPRS 17353931 0006 HT ATG12 SNRPB2 17353931 0006 HT ATG12 LMNB1 17353931 0006 HT ATG12 DDX6 17353931 0006 HT ATG12 MAP1B 20562859,20562859 0007,0004 HT ATG12 HNRNPA3 17353931 0006 HT ATG12 EIF3E 17353931 0006 HT ATG12 RPS29 17353931 0006 HT ATG12 HIST1H2BC|HIST1H2BE|HIST1H2BF|HIST1H2BG|HIST1H2BI 17353931 0006 HT ATG12 OTUD4 17353931,17353931 0006,0004 HT ATG12 TGM3 17353931 0006 HT ATG12 HNRNPA0 17353931 0006 HT ATG12 EIF3A 17353931 0006 HT ATG12 BECN1 20562859 0007 HT ATG12 KRT31 17353931 0006 HT ATG12 SF3A1 17353931,17353931 0006,0004 HT ATG12 MRPL23 17353931 0006 HT ATG12 CDC37 17353931 0006 HT ATG12 PCID2 20562859,20562859 0007,0004 HT ATG12 ATG16L1 17353931,20562859,20562859,17353931 0006,0007,0004,0004 HT ATG12 EBLN2 17353931 0006 HT ATG12 TECPR1 20562859,20562859,22342342 0007,0004,0004 HT,LC ATG12 SERBP1 17353931 0006 HT ATG12 RB1CC1 17353931 0006 HT ATG12 Q96F87 17353931 0006 HT ATG12 HNRNPAB 17353931 0006 HT ATG12 HNRNPUL1 17353931 0006 HT ATG12 ATG10 17353931,26186194,17353931 0006,0004,0004 HT ATG12 ATG5 22342342,20562859,20562859,12890687,17353931,12207896,17353931 0004,0007,0004,0004,0006,0007,0004 LC,HT ATG12 DHX36 17353931,17353931 0006,0004 HT ATG12 RNMTL1 17353931 0006 HT ATG12 MOV10 17353931 0006 HT ATG12 EPB41L5 17353931 0006 HT ATG12 KRT82 17353931 0006 HT ATG12 ATG3 24186333,11825910,20562859,20562859,17353931,12207896,20723759 0096,0004,0007,0004,0006,0007,0004 LC,HT ATG12 CCDC59 17353931 0006 HT ATG12 SUN2 17353931 0006 HT ATG12 MRPS23 17353931 0006 HT ATG12 RPL36 17353931 0006 HT ATG12 CHTOP 17353931 0006 HT ATG12 ATG4B 20562859,20562859 0007,0004 HT ATG12 AUP1 17353931,17353931 0006,0004 HT SF3B1 ATG12 17353931,17353931 0006,0004 HT POP7 ATG12 17353931 0006 HT ATG12 ATG7 20562859,20562859 0007,0004 HT ATG12 EPRS 17353931 0006 HT ATG12 SNRPB2 17353931 0006 HT ATG12 LMNB1 17353931 0006 HT ATG12 DDX6 17353931 0006 HT ATG12 MAP1B 20562859,20562859 0007,0004 HT ATG12 HNRNPA3 17353931 0006 HT ATG12 EIF3E 17353931 0006 HT ATG12 RPS29 17353931 0006 HT ATG12 HIST1H2BC|HIST1H2BE|HIST1H2BF|HIST1H2BG|HIST1H2BI 17353931 0006 HT ATG12 OTUD4 17353931,17353931 0006,0004 HT ATG12 TGM3 17353931 0006 HT ATG12 HNRNPA0 17353931 0006 HT ATG12 EIF3A 17353931 0006 HT ATG12 BECN1 20562859 0007 HT ATG12 KRT31 17353931 0006 HT ATG12 SF3A1 17353931,17353931 0006,0004 HT ATG12 MRPL23 17353931 0006 HT ATG12 CDC37 17353931 0006 HT ATG12 PCID2 20562859,20562859 0007,0004 HT ATG12 ATG16L1 17353931,20562859,20562859,17353931 0006,0007,0004,0004 HT ATG12 EBLN2 17353931 0006 HT ATG12 TECPR1 20562859,20562859 0007,0004 HT ATG12 SERBP1 17353931 0006 HT ATG12 RB1CC1 17353931 0006 HT ATG12 Q96F87 17353931 0006 HT ATG12 HNRNPAB 17353931 0006 HT ATG12 HNRNPUL1 17353931 0006 HT ATG12 ATG10 17353931,26186194,17353931 0006,0004,0004 HT ATG12 ATG5 20562859,20562859,17353931,17353931 0007,0004,0006,0004 HT ATG12 DHX36 17353931,17353931 0006,0004 HT ATG12 RNMTL1 17353931 0006 HT ATG12 MOV10 17353931 0006 HT ATG12 EPB41L5 17353931 0006 HT ATG12 KRT82 17353931 0006 HT ATG12 ATG3 20562859,20562859,17353931 0007,0004,0006 HT ATG12 CCDC59 17353931 0006 HT ATG12 SUN2 17353931 0006 HT ATG12 MRPS23 17353931 0006 HT ATG12 RPL36 17353931 0006 HT ATG12 CHTOP 17353931 0006 HT ATG12 ATG4B 20562859,20562859 0007,0004 HT ATG12 AUP1 17353931,17353931 0006,0004 HT ATG12 TECPR1 22342342 0004 LC ATG12 ATG5 22342342,12890687,12207896 0004,0004,0007 LC ATG12 ATG3 24186333,11825910,12207896,20723759 0096,0004,0007,0004 LC PLSCR1 ATG12 16189514,16189514 0398,0018 HT CRX ATG12 25416956,25416956,25416956,25416956 1112,0397,0018,1356 HT ATG12 ATG7 11096062,11890701,12482611 0018,0018,0018 LC ATG12 PTK2 16189514 0018 HT ATG12 DKFZP666O0110 16189514 0018 HT ATG12 MDFI 16189514,16189514 0398,0018 HT ATG12 KRTAP4-12 16189514,16189514 0398,0018 HT ATG12 DOCK9 23414517 0399 HT ATG12 ATG5 23202584 0114 LC ATG12 ATG3 23202584 0065 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P60228 O94817 EIF3E ATG12 0.236 17353931 O94817 O43186 ATG12 CRX 0.454 25416956 O94817 O15162 ATG12 PLSCR1 0.286 16189514 Q05397 O94817 PTK2 ATG12 0.183 16189514 Q8IZQ1 O94817 WDFY3 ATG12 0.21 20417604 P62273 O94817 RPS29 ATG12 0.236 17353931 Q9HC36 O94817 RNMTL1 ATG12 0.126 17353931 Q9HCE1 O94817 MOV10 ATG12 0.236 17353931 Q9HCM4 O94817 EPB41L5 ATG12 0.236 17353931 Q8NC51 O94817 SERBP1 ATG12 0.236 17353931 Q8R1P4 O94817 ATG10 ATG12 0.376 12890687 Q9NSB4 O94817 KRT82 ATG12 0.126 17353931 Q8TDY2 O94817 RB1CC1 ATG12 0.126 17353931 Q9H2U1 O94817 DHX36 ATG12 0.332 17353931 Q9P031 O94817 CCDC59 ATG12 0.236 17353931 Q9Y679 O94817 AUP1 ATG12 0.332 17353931 Q9Y4P8 O94817 WIPI2 ATG12 0.21 24954904 Q9Y3Y2 O94817 CHTOP ATG12 0.126 17353931 Q9Y3U8 O94817 RPL36 ATG12 0.126 17353931 Q9Y3D9 O94817 MRPS23 ATG12 0.236 17353931 O94817 O75533 ATG12 SF3B1 0.332 17353931 O94817 O75817 ATG12 POP7 0.126 17353931 Q676U5 O94817 ATG16L1 ATG12 0.416 20562859,17353931 P08579 O94817 SNRPB2 ATG12 0.126 17353931 O95786 O94817 DDX58 ATG12 0.033 17709747 P05067 O94817 APP ATG12 0.183 21832049 Q07820 O94817 MCL1 ATG12 0.21 22152474 Q7Z434 O94817 MAVS ATG12 0.033 17709747 Q9BYX4 O94817 IFIH1 ATG12 0.033 17709747 Q9BZ29 O94817 DOCK9 ATG12 0.126 23414517 Q6P2I7 O94817 EBLN2 ATG12 0.126 17353931 Q6P5F9 O94817 XPO1 ATG12 0.126 26673895 Q8C0J2 O94817 ATG16L1 ATG12 0.21 12665549 P11234 O94817 RALB ATG12 0.126 21241894 O95352 O94817 ATG7 ATG12 0.472 20562859,11096062 P07814 O94817 EPRS ATG12 0.126 17353931 Q96A65 O94817 EXOC4 ATG12 0.236 21241894 Q9H0Y0 O94817 ATG10 ATG12 0.416 17353931,26186194 O94817 A4D127 ATG12 MEOX2 {ECO:0000313|EMBL:EAL24289.1} 0.236 unassigned1304 Q9Y4P1 O94817 ATG4B ATG12 0.236 20562859 Q7Z6L1 O94817 TECPR1 ATG12 0.539 20562859,22342342 P46821 O94817 MAP1B ATG12 0.236 20562859 O95166 O94817 GABARAP ATG12 0.236 20562859 Q14140 O94817 SERTAD2 ATG12 0.236 unassigned1304 Q9UHV2 O94817 SERTAD1 ATG12 0.236 unassigned1304 Q9BTL4 O94817 IER2 ATG12 0.236 unassigned1304 Q9H1Y0 O94817 ATG5 ATG12 0.853 20562859,12890687,17353931,22342342,23202584 Q9NT62 O94817 ATG3 ATG12 0.853 20562859,24186333,unassigned1304,17353931,11825910,20723759 P26196 O94817 DDX6 ATG12 0.236 17353931 Q96F87 O94817 Q96F87 ATG12 0.126 17353931 Q9BQ66 O94817 KRTAP4-12 ATG12 0.286 16189514 Q9BUJ2 O94817 HNRNPUL1 ATG12 0.236 17353931 Q99J83 O94817 ATG5 ATG12 0.21 12665549 Q99729 O94817 HNRNPAB ATG12 0.236 17353931 Q99750 O94817 MDFI ATG12 0.286 16189514 Q9CPX6 O94817 ATG3 ATG12 0.569 23202584,20723759 Q9UH99 O94817 SUN2 ATG12 0.236 17353931 P62807 O94817 HIST1H2BI ATG12 0.126 17353931 Q14152 O94817 EIF3A ATG12 0.236 17353931 P42858 O94817 HTT ATG12 0.21 20417604 Q14457 O94817 BECN1 ATG12 0.126 20562859 Q15323 O94817 KRT31 ATG12 0.236 17353931 Q15459 O94817 SF3A1 ATG12 0.236 17353931 Q01804 O94817 OTUD4 ATG12 0.332 17353931 Q13151 O94817 HNRNPA0 ATG12 0.236 17353931 P51991 O94817 HNRNPA3 ATG12 0.126 17353931 Q13158 O94817 FADD ATG12 0.21 15778222 Q03135 O94817 CAV1 ATG12 0.376 24727585 Q16540 O94817 MRPL23 ATG12 0.126 17353931 Q16543 O94817 CDC37 ATG12 0.126 17353931 P20700 O94817 LMNB1 ATG12 0.236 17353931 Q08188 O94817 TGM3 ATG12 0.126 17353931

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 XPO1 ATG12 MI:0045 experimental interaction detection MI:0461 interaction database PLSCR1 ATG12 MI:0045 experimental interaction detection MI:0461 interaction database CRX ATG12 MI:0045 experimental interaction detection MI:0461 interaction database SF3B1 ATG12 MI:0045 experimental interaction detection MI:0461 interaction database POP7 ATG12 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 MFN2 MI:0362 inference MI:1106 pathways database ATG12 GABARAP MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ATG12 ATG7 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ATG12 DDX58 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database ATG12 MYC MI:0045 experimental interaction detection MI:0461 interaction database ATG12 APP MI:0045 experimental interaction detection MI:0461 interaction database ATG12 EPRS MI:0045 experimental interaction detection MI:0461 interaction database ATG12 SNRPB2 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 UBC MI:0045 experimental interaction detection MI:0461 interaction database ATG12 BCL2 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 RALB MI:0045 experimental interaction detection MI:0461 interaction database ATG12 LMNB1 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 TAF1 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 VDAC1 MI:0362 inference MI:1106 pathways database ATG12 DDX6 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 SNCA MI:0362 inference MI:0461 interaction database ATG12 HTT MI:0045 experimental interaction detection MI:0461 interaction database ATG12 MAP1B MI:0045 experimental interaction detection MI:0461 interaction database ATG12 HNRNPA3 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 EIF3E MI:0045 experimental interaction detection MI:0461 interaction database ATG12 GABARAPL2 MI:0362 inference MI:1106 pathways database ATG12 MAX MI:0045 experimental interaction detection MI:0461 interaction database ATG12 RPS29 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 HIST1H2BC MI:0045 experimental interaction detection MI:0461 interaction database ATG12 E2F1 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 OTUD4 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 CAV1 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 PTK2 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 MCL1 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 TGM3 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 HNRNPA0 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 FADD MI:0045 experimental interaction detection MI:0461 interaction database ATG12 SQSTM1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database ATG12 EIF3A MI:0045 experimental interaction detection MI:0461 interaction database ATG12 TRIM25 MI:0362 inference MI:1106 pathways database ATG12 BECN1 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 NBR1 MI:0362 inference MI:0461 interaction database ATG12 KRT31 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 SF3A1 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 MRPL23 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 CDC37 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 ATG16L1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ATG12 EBLN2 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 MAVS MI:0362 inference MI:0461,MI:1106 interaction database,pathways database ATG12 TECPR1 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 RNF135 MI:0362 inference MI:1106 pathways database ATG12 MFN1 MI:0362 inference MI:1106 pathways database ATG12 EXOC8 MI:0362 inference MI:0461 interaction database ATG12 WDFY3 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 SERBP1 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 RB1CC1 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 PDCD6IP MI:0362 inference MI:0461 interaction database ATG12 EXOC4 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 MTERF3 MI:0362 inference MI:1106 pathways database ATG12 EXOC2 MI:0362 inference MI:0461 interaction database ATG12 HNRNPAB MI:0045 experimental interaction detection MI:0461 interaction database ATG12 MDFI MI:0045 experimental interaction detection MI:0461 interaction database ATG12 KRTAP4-12 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 HNRNPUL1 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 MAP1LC3C MI:0362 inference MI:1106 pathways database ATG12 IFIH1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database ATG12 DOCK9 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 MAP1LC3B MI:0362 inference MI:0461,MI:1106 interaction database,pathways database ATG12 RAB33B MI:0362 inference MI:0461 interaction database ATG12 GABARAPL1 MI:0362 inference MI:1106 pathways database ATG12 ATG10 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ATG12 ATG5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ATG12 DHX36 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 MAP1LC3A MI:0362 inference MI:1106 pathways database ATG12 MRM3 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 MOV10 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 EPB41L5 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 KRT82 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 ATG3 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ATG12 CCDC59 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 SUN2 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 EXOC7 MI:0362 inference MI:0461 interaction database ATG12 MRPS23 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 RPL36 MI:0045 experimental interaction detection MI:0461 interaction database ATG12 CHTOP MI:0045 experimental interaction detection MI:0461 interaction database ATG12 ATG4B MI:0045 experimental interaction detection MI:0461 interaction database ATG12 WIPI2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ATG12 AUP1 MI:0045 experimental interaction detection MI:0461 interaction database